Mus musculus

48 known processes

Tyrp1

tyrosinase-related protein 1

(Aliases: brown,Tyrp,b,isa,TRP1,TRP-1)

Tyrp1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
secondary metabolite biosynthetic processGO:0044550111.000
Mouse
phenol containing compound biosynthetic processGO:0046189211.000
Mouse
pigment biosynthetic processGO:0046148260.999
Mouse
melanocyte differentiationGO:0030318250.996
melanin biosynthetic processGO:0042438100.995
Mouse
melanosome organizationGO:003243880.994
pigment cell differentiationGO:0050931270.992
developmental pigmentationGO:0048066400.992
pigment granule localizationGO:0051875130.991
pigmentationGO:0043473710.984
secondary metabolic processGO:0019748180.982
organic hydroxy compound metabolic processGO:19016152030.943
pigment metabolic processGO:0042440320.933
tyrosine metabolic processGO:000657040.859
Mouse
neuroepithelial cell differentiationGO:0060563370.811
melanosome localizationGO:0032400120.773
pigment granule organizationGO:004875390.763
columnar cuboidal epithelial cell differentiationGO:0002065820.751
establishment of melanosome localizationGO:0032401110.718
cellular pigmentationGO:0033059200.681
regulation of phGO:0006885260.651
melanin metabolic processGO:0006582120.630
short chain fatty acid metabolic processGO:004645960.607
melanosome transportGO:0032402110.590
phenol containing compound metabolic processGO:0018958600.524
aromatic amino acid family metabolic processGO:000907290.514
Mouse
rhodopsin mediated signaling pathwayGO:001605640.491
fatty acid metabolic processGO:00066311210.411
monocarboxylic acid metabolic processGO:00327871910.367
catecholamine metabolic processGO:0006584300.352
ketone body metabolic processGO:190222430.301
pigment granule transportGO:0051904120.298
synaptic transmissionGO:00072683290.261
organic hydroxy compound biosynthetic processGO:1901617770.259
Mouse
spermatogenesisGO:00072832840.247
retina development in camera type eyeGO:00600411190.241
transmembrane transportGO:00550854120.205
alpha amino acid metabolic processGO:1901605590.182
Mouse
camera type eye developmentGO:00430102660.175
cellular amine metabolic processGO:0044106440.172
vesicle organizationGO:0016050600.172
positive regulation of urine volumeGO:003581060.167
regulation of urine volumeGO:003580960.160
response to organonitrogen compoundGO:00102432460.158
amine metabolic processGO:0009308450.135
g protein coupled receptor signaling pathwayGO:00071862430.133
cellular amino acid metabolic processGO:00065201030.131
Mouse
sensory organ morphogenesisGO:00905962420.130
cell adhesionGO:00071553290.125
locomotory behaviorGO:00076261950.124
vesicle localizationGO:0051648860.124
developmental maturationGO:00217001930.123
forebrain ventricular zone progenitor cell divisionGO:002186960.122
Mouse
secretory granule organizationGO:0033363200.122
phototransductionGO:0007602170.119
multicellular organismal homeostasisGO:00488711640.119
amide transportGO:00428861380.118
organelle localizationGO:00516401790.117
keratinocyte differentiationGO:0030216480.108
establishment of pigment granule localizationGO:0051905120.106
leukocyte mediated immunityGO:00024431740.101
positive regulation of renal sodium excretionGO:003581520.094
regulation of renal sodium excretionGO:003581330.094
regulation of neuroblast proliferationGO:1902692270.094
Mouse
circulatory system processGO:00030131970.093
amino acid transmembrane transportGO:0003333370.090
placenta developmentGO:00018901400.087
organic acid biosynthetic processGO:0016053860.087
cellular component assembly involved in morphogenesisGO:00109271390.086
lipid localizationGO:00108761260.077
spermatid developmentGO:00072861080.077
regulation of body fluid levelsGO:00508781620.076
organonitrogen compound biosynthetic processGO:19015661920.075
nucleobase containing small molecule metabolic processGO:00550863520.074
cellular lipid metabolic processGO:00442553230.074
detection of stimulusGO:0051606840.074
male gamete generationGO:00482322850.073
nucleoside phosphate biosynthetic processGO:1901293790.072
detection of external stimulusGO:0009581610.071
dopamine biosynthetic processGO:004241660.071
skeletal system morphogenesisGO:00487052030.070
cellular ion homeostasisGO:00068731650.070
visual perceptionGO:0007601520.069
anion transportGO:00068201770.069
anion transmembrane transportGO:0098656710.069
purine nucleotide biosynthetic processGO:0006164650.065
hair follicle developmentGO:0001942850.065
regulation of homeostatic processGO:00328441820.065
negative regulation of molecular functionGO:00440922580.065
carbohydrate derivative biosynthetic processGO:19011371830.063
cyclic nucleotide biosynthetic processGO:0009190440.062
cyclic purine nucleotide metabolic processGO:0052652430.061
blood vessel morphogenesisGO:00485142850.060
connective tissue developmentGO:00614481790.060
dopamine metabolic processGO:0042417230.060
retinal cone cell developmentGO:004654980.060
positive regulation of kinase activityGO:00336741550.058
organophosphate biosynthetic processGO:00904071220.057
defecationGO:003042110.056
photoreceptor cell developmentGO:0042461400.055
oligopeptide transmembrane transportGO:003567240.054
camp biosynthetic processGO:0006171310.054
learningGO:0007612980.054
negative regulation of protein metabolic processGO:00512482820.053
cyclic nucleotide metabolic processGO:0009187590.052
cation homeostasisGO:00550802120.052
positive regulation of neuroblast proliferationGO:0002052190.050
Mouse
small molecule biosynthetic processGO:00442831320.050
regulation of system processGO:00440572000.050
regulation of metal ion transportGO:00109591060.049
cellular response to organonitrogen compoundGO:00714171450.049
epithelial cell developmentGO:00020641590.049
ventricular zone neuroblast divisionGO:002184730.048
Mouse
stem cell proliferationGO:00720891170.048
Mouse
cellular chemical homeostasisGO:00550822150.047
nucleotide metabolic processGO:00091173320.047
regulation of neural precursor cell proliferationGO:2000177700.047
Mouse
lipid homeostasisGO:0055088630.047
positive regulation of growthGO:00459271040.046
ion transmembrane transportGO:00342203610.046
regulation of protein localizationGO:00328802310.046
cell divisionGO:00513011200.045
Mouse
response to drugGO:0042493750.045
regulation of camp biosynthetic processGO:0030817250.043
neuron maturationGO:0042551290.043
nitrogen compound transportGO:00717052710.043
response to light stimulusGO:00094161350.043
nucleoside metabolic processGO:00091162460.043
purine containing compound biosynthetic processGO:0072522700.042
response to hypoxiaGO:0001666580.042
cation transportGO:00068123990.041
phototransduction visible lightGO:000760360.041
regulation of response to woundingGO:19030341890.040
regulation of cyclic nucleotide metabolic processGO:0030799400.039
regulation of feeding behaviorGO:006025930.039
intermediate filament cytoskeleton organizationGO:0045104260.039
dopamine biosynthetic process from tyrosineGO:000658510.038
cytoplasmic transportGO:00164822340.038
negative regulation of cell proliferationGO:00082852960.038
second messenger mediated signalingGO:0019932730.038
response to oxidative stressGO:00069791230.038
eye photoreceptor cell developmentGO:0042462310.037
response to hydrogen peroxideGO:0042542320.037
intermediate filament organizationGO:0045109150.037
midgut developmentGO:000749440.037
chloride transportGO:0006821320.037
cell proliferation in forebrainGO:0021846300.036
Mouse
respiratory gaseous exchangeGO:0007585430.036
activation of adenylate cyclase activityGO:000719040.036
reactive oxygen species metabolic processGO:0072593840.035
sensory perceptionGO:00076002450.035
carbohydrate transportGO:0008643620.035
negative regulation of peptidase activityGO:0010466460.035
response to peptideGO:19016521360.035
negative regulation of cellular protein metabolic processGO:00322692470.035
positive regulation of synaptic plasticityGO:003191540.034
detection of light stimulusGO:0009583250.034
cellular response to acid chemicalGO:0071229680.034
fatty acid biosynthetic processGO:0006633410.034
forebrain developmentGO:00309003020.034
Mouse
nucleotide biosynthetic processGO:0009165780.034
establishment of organelle localizationGO:00516561220.033
regulation of smoothened signaling pathwayGO:0008589580.033
adult behaviorGO:00305341350.033
skin developmentGO:00435882200.033
positive regulation of keratinocyte proliferationGO:001083840.032
steroid metabolic processGO:00082021190.032
cellular response to inorganic substanceGO:0071241370.032
negative regulation of intracellular signal transductionGO:19025321670.031
photoreceptor cell differentiationGO:0046530520.031
regulation of protein maturationGO:1903317960.031
carboxylic acid biosynthetic processGO:0046394860.031
negative regulation of phosphate metabolic processGO:00459361840.030
lipid biosynthetic processGO:00086101790.030
cellular response to lipidGO:00713961450.030
regulation of cellular ketone metabolic processGO:0010565660.030
negative regulation of kinase activityGO:0033673810.030
microtubule based movementGO:0007018840.030
magnesium ion homeostasisGO:001096060.030
ribose phosphate biosynthetic processGO:0046390590.029
negative regulation of phosphorus metabolic processGO:00105631840.028
limb morphogenesisGO:00351081490.028
calcium ion transportGO:00068161590.027
circadian rhythmGO:00076231140.027
regulation of inflammatory responseGO:00507271470.027
wound healingGO:00420601570.027
organic acid transportGO:00158491010.027
regulation of bmp signaling pathwayGO:0030510600.026
temperature homeostasisGO:0001659260.026
blood circulationGO:00080151950.026
regulation of purine nucleotide biosynthetic processGO:1900371340.026
cellular response to molecule of bacterial originGO:0071219830.026
sensory perception of light stimulusGO:0050953540.025
stem cell differentiationGO:00488632680.025
digestive system developmentGO:00551232000.025
regulation of protein secretionGO:0050708820.025
monosaccharide transportGO:0015749580.025
catecholamine biosynthetic processGO:0042423110.025
protein targetingGO:00066051430.025
microtubule based processGO:00070172360.025
regulation of cellular amine metabolic processGO:0033238200.025
cellular response to lipopolysaccharideGO:0071222770.025
regulation of response to drugGO:200102320.024
cell differentiation involved in embryonic placenta developmentGO:0060706260.024
cellular homeostasisGO:00197252400.024
negative regulation of protein maturationGO:1903318790.024
semaphorin plexin signaling pathway involved in outflow tract morphogenesisGO:007152710.024
regulation of nucleotide biosynthetic processGO:0030808340.024
negative regulation of response to oxidative stressGO:1902883100.024
positive regulation of neural precursor cell proliferationGO:2000179420.024
Mouse
negative regulation of lymphocyte activationGO:0051250910.024
negative regulation of camp metabolic processGO:003081550.024
protein maturationGO:00516041760.024
cellular divalent inorganic cation homeostasisGO:00725031270.024
regulation of secretion by cellGO:19035302490.023
maintenance of locationGO:0051235890.023
response to molecule of bacterial originGO:00022371430.023
t helper 2 cell cytokine productionGO:003574540.023
cellular response to calcium ionGO:0071277140.023
regulation of penile erectionGO:006040510.022
organic anion transportGO:00157111370.022
monocarboxylic acid transportGO:0015718440.022
inorganic anion transmembrane transportGO:0098661290.022
response to acid chemicalGO:00011011110.022
blood coagulationGO:0007596760.022
retinal cone cell differentiationGO:004267080.022
regulation of nucleotide metabolic processGO:00061401690.022
response to coldGO:0009409190.022
response to reactive oxygen speciesGO:0000302560.022
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.022
hair follicle morphogenesisGO:0031069290.022
response to inorganic substanceGO:0010035960.022
positive regulation of cell developmentGO:00107202370.022
Mouse
ribonucleotide biosynthetic processGO:0009260590.022
canonical wnt signaling pathway involved in negative regulation of apoptotic processGO:004433640.021
regulation of muscle contractionGO:0006937490.021
response to organic cyclic compoundGO:00140701980.021
respiratory tube developmentGO:00303231670.021
defense response to gram positive bacteriumGO:0050830500.021
muscle contractionGO:00069361010.021
membrane organizationGO:00610242450.021
regulation of blood pressureGO:0008217930.020
cation transmembrane transportGO:00986552660.020
epithelial tube morphogenesisGO:00605623030.020
cellular response to light stimulusGO:0071482190.020
purine nucleotide metabolic processGO:00061633020.020
regulation of cell activationGO:00508652890.020
regulation of developmental pigmentationGO:0048070140.020
cell chemotaxisGO:0060326810.020
regulation of kinase activityGO:00435492490.020
positive regulation of protein modification processGO:00314012990.020
organic hydroxy compound transportGO:0015850930.020
ribonucleotide metabolic processGO:00092592910.019
regulation of endocytosisGO:0030100690.019
lysosome organizationGO:0007040210.019
calcium ion homeostasisGO:00550741270.019
renal sodium excretionGO:003581230.019
cellular response to metal ionGO:0071248310.019
regulation of protein processingGO:0070613960.019
cellular response to carbohydrate stimulusGO:0071322500.019
stem cell developmentGO:00488642190.019
innate immune responseGO:00450871570.018
regulation of secretionGO:00510462740.018
thymus developmentGO:0048538410.018
Mouse
glucose homeostasisGO:00425931280.018
smoothened signaling pathwayGO:00072241050.018
intermediate filament based processGO:0045103270.018
regulation of protein transportGO:00512231630.018
purine containing compound metabolic processGO:00725213110.018
monocarboxylic acid biosynthetic processGO:0072330610.018
cellular response to biotic stimulusGO:0071216920.018
monovalent inorganic cation homeostasisGO:0055067330.018
regulation of hormone levelsGO:00108172110.018
i kappab kinase nf kappab signalingGO:0007249850.018
positive regulation of secretionGO:00510471300.018
detection of abiotic stimulusGO:0009582600.018
negative regulation of protein phosphorylationGO:00019331260.017
protein localization to membraneGO:00726571080.017
peptide transportGO:00158331330.017
divalent inorganic cation homeostasisGO:00725071380.017
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formationGO:200080210.017
retina morphogenesis in camera type eyeGO:0060042450.017
chloride transmembrane transportGO:1902476240.017
positive regulation of cellular amino acid metabolic processGO:004576430.017
protein secretionGO:00093061110.017
carboxylic acid transportGO:00469421000.017
cell communication by electrical coupling involved in cardiac conductionGO:008606420.017
inorganic ion transmembrane transportGO:00986602340.017
cellular ketone metabolic processGO:0042180840.017
lipid transportGO:0006869980.017
regulation of lipid metabolic processGO:00192161180.017
eye pigmentationGO:004806930.016
positive regulation of nervous system developmentGO:00519622210.016
Mouse
lymphocyte mediated immunityGO:00024491390.016
natural killer cell activationGO:0030101440.016
embryonic placenta developmentGO:0001892980.016
enteric smooth muscle cell differentiationGO:003564510.016
cellular response to organic cyclic compoundGO:0071407870.016
response to temperature stimulusGO:0009266550.016
atrial ventricular junction remodelingGO:000329420.016
vascular process in circulatory systemGO:0003018620.016
ear developmentGO:00435832000.016
purine ribonucleoside metabolic processGO:00461282410.016
epithelial cell proliferationGO:00506731740.016
bone remodelingGO:0046849530.015
response to lipopolysaccharideGO:00324961280.015
regulation of transcription from rna polymerase iii promoterGO:000635920.015
smooth muscle contractionGO:0006939440.015
leukocyte chemotaxisGO:0030595690.015
cartilage developmentGO:00512161400.015
negative regulation of immune system processGO:00026832090.015
neuron neuron synaptic transmissionGO:0007270690.015
regulation of protein serine threonine kinase activityGO:00719001570.015
neural precursor cell proliferationGO:00613511210.015
Mouse
muscle cell differentiationGO:00426922610.015
positive regulation of catecholamine metabolic processGO:004591520.015
somatic stem cell divisionGO:0048103190.015
Mouse
oculomotor nerve morphogenesisGO:002162220.015
membrane hyperpolarizationGO:0060081210.015
sensory perception of smellGO:0007608260.015
regulation of reactive oxygen species metabolic processGO:2000377400.015
myeloid cell differentiationGO:00300992330.015
megakaryocyte differentiationGO:0030219260.015
negative regulation of nucleotide biosynthetic processGO:003080960.015
negative regulation of inflammatory responseGO:0050728610.014
ensheathment of neuronsGO:0007272760.014
cell maturationGO:00484691270.014
response to radiationGO:00093141650.014
peptide hormone secretionGO:00300721090.014
negative regulation of oxidative phosphorylation uncoupler activityGO:200027620.014
tumor necrosis factor productionGO:0032640500.014
transcription from rna polymerase iii promoterGO:000638330.014
stem cell divisionGO:0017145300.014
Mouse
response to iron ionGO:001003940.014
defense response to bacteriumGO:00427421190.014
response to nutrient levelsGO:00316671090.014
positive regulation of immune effector processGO:00026991070.014
anatomical structure homeostasisGO:00602491450.014
negative regulation of protein modification processGO:00314001630.014
negative regulation of proteolysisGO:0045861740.014
positive regulation of secretion by cellGO:19035321140.014
carbohydrate biosynthetic processGO:0016051740.014
posttranscriptional regulation of gene expressionGO:00106081550.014
molting cycleGO:0042303900.014
organelle assemblyGO:00709251770.014
endothelial cell differentiationGO:0045446410.014
cellular response to oxidative stressGO:0034599760.014
regulation of cellular carbohydrate metabolic processGO:0010675750.014
regulation of ion transportGO:00432692150.014
pallium developmentGO:00215431200.014
hair cycleGO:0042633900.014
bmp signaling pathwayGO:0030509930.014
gliogenesisGO:00420631410.014
cellular metal ion homeostasisGO:00068751510.014
positive regulation of cellular amine metabolic processGO:003324050.014
chemotaxisGO:00069352470.014
regulation of myoblast differentiationGO:0045661290.013
auditory receptor cell fate specificationGO:004266710.013
tube formationGO:00351481400.013
sensory perception of chemical stimulusGO:0007606510.013
positive regulation of inner ear receptor cell differentiationGO:200098210.013
excretionGO:0007588220.013
mesenchymal cell developmentGO:0014031930.013
regulation of chloride transportGO:200122520.013
positive regulation of epidermis developmentGO:0045684130.013
digestionGO:0007586400.013
regulation of cell cycle processGO:00105641600.013
lung developmentGO:00303241640.013
cerebellar granule cell precursor proliferationGO:0021930100.013
limb developmentGO:00601731660.013
positive regulation of leukocyte mediated immunityGO:0002705700.013
adult feeding behaviorGO:000834390.013
regulation of myotube differentiationGO:0010830620.013
rhythmic processGO:00485111740.013
glial cell differentiationGO:00100011310.013
response to histamineGO:003477610.013
neuroblast proliferationGO:0007405490.013
Mouse
negative regulation of purine nucleotide metabolic processGO:1900543160.013
regulation of multi organism processGO:00439001110.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
lung epithelial cell differentiationGO:0060487290.012
establishment of vesicle localizationGO:0051650810.012
ossificationGO:00015032160.012
neural retina developmentGO:0003407410.012
regulation of oxidative phosphorylation uncoupler activityGO:200027530.012
cellular response to hormone stimulusGO:00328701500.012
muscle system processGO:00030121410.012
nucleoside phosphate metabolic processGO:00067533380.012
cytokine productionGO:00018163190.012
detection of visible lightGO:0009584140.012
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic processGO:200076310.012
gastrulationGO:00073691160.012
regulation of dopamine secretionGO:001405990.012
adaptive immune responseGO:00022501550.012
hexose transportGO:0008645560.012
retinal bipolar neuron differentiationGO:006004050.011
dipeptide transportGO:004293820.011
regulation of endocardial cushion to mesenchymal transition involved in heart valve formationGO:200080010.011
multicellular organism growthGO:00352641610.011
tendon cell differentiationGO:003599040.011
apoptotic signaling pathwayGO:00971903060.011
fatty acid derivative metabolic processGO:1901568330.011
regulation of peptidase activityGO:0052547960.011
hematopoietic progenitor cell differentiationGO:00022441430.011
negative regulation of hydrolase activityGO:0051346710.011
cellular response to prostaglandin stimulusGO:007137920.011
transforming growth factor beta secretionGO:003804410.011
regulation of cell shapeGO:0008360390.011
endocrine processGO:0050886390.011
inorganic cation transmembrane transportGO:00986622070.011
regulation of protein kinase activityGO:00458592320.011
epithelial fluid transportGO:004204510.011
immune response regulating signaling pathwayGO:00027641250.011
cellular response to prostaglandin e stimulusGO:007138010.011
cognitionGO:00508901490.011
regulation of g protein coupled receptor protein signaling pathwayGO:0008277370.011
regulation of cellular amino acid metabolic processGO:000652150.011
adaptation of rhodopsin mediated signalingGO:001606220.011
regulation of pigment cell differentiationGO:005093270.011
regulation of myeloid cell differentiationGO:0045637960.011
actin filament based movementGO:0030048230.011
response to monosaccharideGO:0034284670.011
regulation of cytokine secretionGO:0050707610.011
l alpha amino acid transmembrane transportGO:1902475230.011
response to metal ionGO:0010038470.011
regulation of satellite cell activation involved in skeletal muscle regenerationGO:001471730.011
potassium ion homeostasisGO:005507540.011
synaptic transmission gabaergicGO:0051932190.011
purine containing compound catabolic processGO:00725232130.011
regulation of blood vessel sizeGO:0050880560.011
feeding behaviorGO:0007631620.010
learning or memoryGO:00076111480.010
hexose biosynthetic processGO:0019319390.010
positive regulation of cytokine secretionGO:0050715410.010
transmission of nerve impulseGO:0019226760.010
cardiac neural crest cell migration involved in outflow tract morphogenesisGO:000325330.010
nuclear divisionGO:00002801580.010
regulation of epithelial cell proliferationGO:00506781410.010
tendon formationGO:003599240.010
regulation of stem cell proliferationGO:0072091780.010
Mouse
cell proliferation in hindbrainGO:0021534100.010
purine ribonucleotide biosynthetic processGO:0009152590.010
neuronal action potentialGO:0019228540.010
respiratory system developmentGO:00605411900.010

Tyrp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
retinal diseaseDOID:567900.168
sensory system diseaseDOID:005015500.168
disease of anatomical entityDOID:700.168
eye diseaseDOID:561400.168
nervous system diseaseDOID:86300.168
eye and adnexa diseaseDOID:149200.168
night blindnessDOID:849900.138
retinal degenerationDOID:846600.095
retinitis pigmentosaDOID:1058400.095
gastrointestinal system diseaseDOID:7700.027
waardenburg s syndromeDOID:925800.024