Mus musculus

0 known processes

Polr2b

polymerase (RNA) II (DNA directed) polypeptide B

(Aliases: MGC47046,Rpb140,Rpb2,Pol2rb)

Polr2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.151
rna processingGO:00063961050.124
dna repairGO:00062811070.099
organelle fissionGO:00482851700.093
somatic diversification of immunoglobulinsGO:0016445430.090
stem cell developmentGO:00488642190.081
gene silencing by rnaGO:0031047190.067
axonogenesisGO:00074092740.066
ncrna 3 end processingGO:004362820.065
stem cell differentiationGO:00488632680.061
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.061
rna splicing via transesterification reactionsGO:0000375430.061
mitotic nuclear divisionGO:0007067480.061
nucleoside metabolic processGO:00091162460.061
cellular nitrogen compound catabolic processGO:00442702800.060
posttranscriptional regulation of gene expressionGO:00106081550.057
cellular amino acid metabolic processGO:00065201030.055
rna splicingGO:0008380540.054
endocytosisGO:00068971680.053
aromatic compound catabolic processGO:00194392860.051
mitotic cell cycle processGO:19030471590.051
atp catabolic processGO:0006200550.049
nuclear divisionGO:00002801580.049
regulation of cellular response to stressGO:00801351590.048
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.045
mitotic cell cycleGO:00002781950.045
chromatin organizationGO:00063252060.045
organelle assemblyGO:00709251770.045
ras protein signal transductionGO:0007265770.044
microtubule based processGO:00070172360.043
peptidyl amino acid modificationGO:00181933360.041
cell type specific apoptotic processGO:00972852680.040
defense response to other organismGO:00985421970.040
atp metabolic processGO:0046034750.040
purine ribonucleoside monophosphate metabolic processGO:0009167800.039
purine nucleoside monophosphate catabolic processGO:0009128580.038
regulation of organelle organizationGO:00330432890.038
purine nucleotide metabolic processGO:00061633020.038
nucleobase containing small molecule metabolic processGO:00550863520.038
ribose phosphate metabolic processGO:00196932910.038
organophosphate catabolic processGO:00464342320.036
organic cyclic compound catabolic processGO:19013612950.036
purine nucleotide catabolic processGO:00061952110.035
nucleoside monophosphate catabolic processGO:0009125590.035
apoptotic signaling pathwayGO:00971903060.035
histone modificationGO:00165701590.035
purine ribonucleoside metabolic processGO:00461282410.034
glycosyl compound metabolic processGO:19016572460.034
nucleoside phosphate catabolic processGO:19012922220.034
histone lysine methylationGO:0034968500.033
negative regulation of histone h3 k9 methylationGO:005157340.032
ribonucleoside monophosphate catabolic processGO:0009158570.032
ribonucleotide catabolic processGO:00092612080.032
posttranscriptional gene silencingGO:0016441100.031
heterocycle catabolic processGO:00467002800.031
germ cell developmentGO:00072811850.031
microtubule cytoskeleton organizationGO:00002261570.030
regulation of chromosome organizationGO:0033044830.030
double strand break repairGO:0006302480.030
double strand break repair via nonhomologous end joiningGO:0006303100.029
mrna metabolic processGO:0016071840.029
somatic diversification of immune receptorsGO:0002200530.028
production of molecular mediator of immune responseGO:00024401030.028
nucleic acid phosphodiester bond hydrolysisGO:0090305490.028
lymphocyte mediated immunityGO:00024491390.027
purine nucleoside metabolic processGO:00422782410.027
regulation of chromatin modificationGO:1903308570.027
axon guidanceGO:00074111410.026
immune effector processGO:00022523210.026
purine containing compound catabolic processGO:00725232130.026
posttranscriptional gene silencing by rnaGO:0035194100.026
ribonucleoside catabolic processGO:00424542060.025
small gtpase mediated signal transductionGO:0007264970.025
purine nucleoside monophosphate metabolic processGO:0009126810.025
ribonucleoside triphosphate catabolic processGO:00092031990.025
purine ribonucleoside triphosphate metabolic processGO:00092052200.025
intracellular protein transportGO:00068862040.025
chemotaxisGO:00069352470.025
development of primary sexual characteristicsGO:00451371430.025
purine containing compound metabolic processGO:00725213110.024
snrna metabolic processGO:001607310.024
protein localization to nucleusGO:00345041210.024
dna templated transcription terminationGO:000635340.024
placenta developmentGO:00018901400.024
nucleotide metabolic processGO:00091173320.023
dna recombinationGO:0006310920.023
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.023
nucleotide catabolic processGO:00091662170.023
gonad developmentGO:00084061410.023
regulation of cellular ketone metabolic processGO:0010565660.023
ribonucleotide metabolic processGO:00092592910.023
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.023
locomotory behaviorGO:00076261950.022
extrinsic apoptotic signaling pathwayGO:00971911260.022
neuron deathGO:00709971540.022
dna templated transcriptional preinitiation complex assemblyGO:007089740.022
lateral inhibitionGO:004633110.022
purine nucleoside triphosphate catabolic processGO:00091462030.022
mesenchymal cell differentiationGO:00487621070.022
response to organic cyclic compoundGO:00140701980.021
leukocyte activation involved in immune responseGO:00023661260.020
nucleoside phosphate metabolic processGO:00067533380.020
cellular response to dna damage stimulusGO:00069742070.020
methylationGO:00322591340.020
cytoplasmic transportGO:00164822340.020
purine ribonucleoside catabolic processGO:00461302050.020
purine ribonucleoside monophosphate catabolic processGO:0009169570.020
positive regulation of cell deathGO:00109422240.020
neuron projection guidanceGO:00974851410.020
rna phosphodiester bond hydrolysisGO:0090501190.019
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.019
regulation of cellular component biogenesisGO:00440871810.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
ameboidal type cell migrationGO:00016671280.019
negative regulation of cell proliferationGO:00082852960.018
mrna splicing via spliceosomeGO:0000398430.018
purine nucleoside catabolic processGO:00061522050.018
trna wobble uridine modificationGO:000209820.018
interspecies interaction between organismsGO:0044419830.018
positive regulation of cellular amino acid metabolic processGO:004576430.018
action potentialGO:0001508780.018
gene silencingGO:0016458380.017
response to extracellular stimulusGO:00099911270.017
regulation of actin filament based processGO:0032970990.017
rna interferenceGO:001624620.017
trna aminoacylationGO:004303910.017
snrna 3 end processingGO:003447210.017
trna metabolic processGO:0006399110.017
immunoglobulin productionGO:0002377730.017
positive regulation of growthGO:00459271040.017
adult behaviorGO:00305341350.017
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.017
cell cycle checkpointGO:0000075470.017
ribonucleoside triphosphate metabolic processGO:00091992200.017
receptor mediated endocytosisGO:0006898510.017
protein acylationGO:0043543640.017
establishment of protein localization to organelleGO:00725941180.016
nucleotide excision repairGO:0006289130.016
trna aminoacylation for protein translationGO:000641810.016
regulation of response to dna damage stimulusGO:2001020340.016
cell activation involved in immune responseGO:00022631260.016
neuron apoptotic processGO:00514021420.015
purine ribonucleotide metabolic processGO:00091502900.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.015
olfactory learningGO:000835520.015
ncrna processingGO:0034470260.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.015
regulation of intracellular transportGO:00323861590.015
positive regulation of apoptotic processGO:00430652170.015
nucleoside monophosphate metabolic processGO:0009123850.015
stem cell maintenanceGO:00198271300.015
nucleocytoplasmic transportGO:00069131390.015
macromolecule methylationGO:00434141200.015
mrna processingGO:0006397630.014
protein localization to organelleGO:00333651850.014
single fertilizationGO:0007338820.014
gland developmentGO:00487323300.014
glycosyl compound catabolic processGO:19016582060.014
chromatin modificationGO:00165681870.014
fertilizationGO:00095661270.014
maintenance of locationGO:0051235890.014
multicellular organismal agingGO:0010259240.013
response to transforming growth factor betaGO:0071559880.013
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.013
leukocyte mediated immunityGO:00024431740.013
maturation of ssu rrnaGO:003049010.013
regulation of cellular amino acid metabolic processGO:000652150.013
purine ribonucleoside triphosphate catabolic processGO:00092071990.013
ribonucleoside monophosphate metabolic processGO:0009161800.013
cellular protein complex assemblyGO:00436231160.013
protein processingGO:00164851630.013
macromolecule catabolic processGO:00090572810.013
multicellular organismal signalingGO:0035637910.013
ribonucleoside metabolic processGO:00091192450.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.013
nuclear transcribed mrna catabolic processGO:0000956160.013
cellular macromolecule catabolic processGO:00442652060.013
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046210.013
maturation of 5 8s rrnaGO:000046010.013
symbiosis encompassing mutualism through parasitismGO:0044403830.013
regulation of cell cycle phase transitionGO:1901987770.012
maternal determination of anterior posterior axis embryoGO:000835820.012
cell recognitionGO:0008037830.012
positive regulation of programmed cell deathGO:00430682180.012
response to insulinGO:00328681000.012
carbohydrate derivative catabolic processGO:19011362310.012
somatic recombination of immunoglobulin gene segmentsGO:0016447420.012
regulation of hormone levelsGO:00108172110.012
male gamete generationGO:00482322850.012
snrna processingGO:001618010.012
cation transmembrane transportGO:00986552660.012
molting cycleGO:0042303900.012
maintenance of protein location in nucleusGO:005145720.012
leukocyte apoptotic processGO:0071887710.012
multicellular organismal homeostasisGO:00488711640.012
regulation of histone modificationGO:0031056560.012
regulation of protein stabilityGO:0031647520.012
amine metabolic processGO:0009308450.012
positive regulation of nervous system developmentGO:00519622210.012
divalent metal ion transportGO:00708381720.012
trna wobble base modificationGO:000209720.012
regulation of cell cycle processGO:00105641600.012
regulation of chromatin silencingGO:003193520.012
response to organonitrogen compoundGO:00102432460.012
protein deacetylationGO:0006476320.011
cellular response to growth factor stimulusGO:00713631970.011
positive regulation of intracellular transportGO:0032388700.011
regulation of cell growthGO:0001558910.011
tubulin deacetylationGO:009004240.011
tissue homeostasisGO:00018941150.011
negative regulation of molecular functionGO:00440922580.011
regulation of dna damage checkpointGO:200000130.011
protein targetingGO:00066051430.011
inorganic cation transmembrane transportGO:00986622070.011
lipid biosynthetic processGO:00086101790.011
regulation of multi organism processGO:00439001110.011
dna conformation changeGO:0071103370.011
negative regulation of protein phosphorylationGO:00019331260.011
meiotic cell cycleGO:00513211220.011
negative regulation of cellular protein metabolic processGO:00322692470.011
cell adhesionGO:00071553290.011
positive regulation of protein modification processGO:00314012990.011
non recombinational repairGO:0000726100.011
cell cell recognitionGO:0009988440.011
response to peptideGO:19016521360.011
b cell activation involved in immune responseGO:0002312500.011
forebrain developmentGO:00309003020.011
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046610.011
sperm egg recognitionGO:0035036370.010
response to light stimulusGO:00094161350.010
trna processingGO:0008033110.010
b cell activationGO:00421131610.010
nucleoside triphosphate catabolic processGO:00091432050.010
nitrogen compound transportGO:00717052710.010
dendrite developmentGO:00163581150.010
ribosomal small subunit biogenesisGO:004227440.010

Polr2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.107
disease of anatomical entityDOID:700.107
central nervous system diseaseDOID:33100.014
neurodegenerative diseaseDOID:128900.013
sensory system diseaseDOID:005015500.011
eye and adnexa diseaseDOID:149200.011