| response to radiation | GO:0009314 | 165 | 0.947 | |
| response to light stimulus | GO:0009416 | 135 | 0.941 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 73 | 0.901 | Human |
| regulation of intracellular transport | GO:0032386 | 159 | 0.899 | Human |
| regulation of defense response | GO:0031347 | 233 | 0.894 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.893 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.880 | |
| response to uv | GO:0009411 | 44 | 0.859 | |
| immune effector process | GO:0002252 | 321 | 0.854 | |
| adaptive immune response | GO:0002250 | 155 | 0.852 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.847 | |
| toll like receptor signaling pathway | GO:0002224 | 38 | 0.829 | |
| nuclear transport | GO:0051169 | 139 | 0.825 | Human |
| autophagy | GO:0006914 | 45 | 0.814 | |
| regulation of lymphocyte proliferation | GO:0050670 | 117 | 0.810 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.806 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 85 | 0.805 | Human |
| regulation of protein import into nucleus | GO:0042306 | 52 | 0.798 | Human |
| macromolecule catabolic process | GO:0009057 | 281 | 0.794 | |
| defense response to other organism | GO:0098542 | 197 | 0.784 | Fly |
| ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway | GO:0043162 | 3 | 0.767 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.759 | |
| protein maturation | GO:0051604 | 176 | 0.733 | |
| protein modification by small protein removal | GO:0070646 | 21 | 0.719 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.718 | |
| regulation of protein localization | GO:0032880 | 231 | 0.708 | Human |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.707 | Human |
| regulation of leukocyte proliferation | GO:0070663 | 121 | 0.698 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.693 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.687 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.670 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.666 | |
| positive regulation of t cell anergy | GO:0002669 | 4 | 0.663 | |
| regulation of response to biotic stimulus | GO:0002831 | 38 | 0.654 | |
| regulation of t cell anergy | GO:0002667 | 4 | 0.653 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.645 | Human |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 40 | 0.635 | |
| amine metabolic process | GO:0009308 | 45 | 0.623 | |
| defense response to bacterium | GO:0042742 | 119 | 0.619 | Fly |
| signal transduction by p53 class mediator | GO:0072331 | 51 | 0.618 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.612 | |
| t cell proliferation | GO:0042098 | 120 | 0.611 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.607 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.603 | |
| t cell activation | GO:0042110 | 289 | 0.601 | |
| intracellular receptor signaling pathway | GO:0030522 | 74 | 0.598 | |
| mapk cascade | GO:0000165 | 281 | 0.596 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.594 | Human |
| cytoplasmic transport | GO:0016482 | 234 | 0.590 | Human |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.589 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.585 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.584 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.583 | Human |
| coenzyme biosynthetic process | GO:0009108 | 23 | 0.579 | |
| cellular response to lipid | GO:0071396 | 145 | 0.572 | |
| response to osmotic stress | GO:0006970 | 21 | 0.572 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.570 | Human |
| regulation of protein targeting | GO:1903533 | 61 | 0.569 | Human |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.556 | |
| protein polyubiquitination | GO:0000209 | 33 | 0.554 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.553 | |
| cellular amide metabolic process | GO:0043603 | 58 | 0.553 | |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.548 | |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.546 | |
| negative regulation of cell activation | GO:0050866 | 111 | 0.540 | |
| cellular response to molecule of bacterial origin | GO:0071219 | 83 | 0.538 | |
| cellular response to lipopolysaccharide | GO:0071222 | 77 | 0.531 | |
| immune response activating signal transduction | GO:0002757 | 116 | 0.522 | |
| ossification | GO:0001503 | 216 | 0.517 | |
| skin development | GO:0043588 | 220 | 0.510 | |
| spleen development | GO:0048536 | 39 | 0.507 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.507 | Human |
| regulation of myeloid cell differentiation | GO:0045637 | 96 | 0.504 | |
| negative regulation of t cell proliferation | GO:0042130 | 38 | 0.503 | |
| response to growth factor | GO:0070848 | 198 | 0.502 | |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.500 | |
| protein import into nucleus | GO:0006606 | 95 | 0.496 | Human |
| regulation of t cell proliferation | GO:0042129 | 92 | 0.493 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.485 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.484 | Human |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.477 | |
| positive regulation of fatty acid biosynthetic process | GO:0045723 | 3 | 0.475 | |
| b cell mediated immunity | GO:0019724 | 71 | 0.468 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.468 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.467 | |
| ripoptosome assembly involved in necroptotic process | GO:1901026 | 6 | 0.464 | |
| cellular response to radiation | GO:0071478 | 28 | 0.456 | |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 145 | 0.455 | |
| regulation of notch signaling pathway | GO:0008593 | 35 | 0.452 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.445 | |
| regulation of lipid metabolic process | GO:0019216 | 118 | 0.438 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 57 | 0.434 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.433 | |
| lipid biosynthetic process | GO:0008610 | 179 | 0.429 | |
| b cell differentiation | GO:0030183 | 78 | 0.428 | |
| regulation of metal ion transport | GO:0010959 | 106 | 0.426 | |
| peptide metabolic process | GO:0006518 | 46 | 0.425 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.424 | |
| protein ubiquitination | GO:0016567 | 171 | 0.424 | |
| t cell anergy | GO:0002870 | 4 | 0.422 | |
| necrotic cell death | GO:0070265 | 30 | 0.414 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.412 | |
| regulation of transcription factor import into nucleus | GO:0042990 | 24 | 0.410 | Human |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.407 | |
| positive regulation of ion transport | GO:0043270 | 65 | 0.405 | |
| stress activated protein kinase signaling cascade | GO:0031098 | 81 | 0.405 | Fly |
| alpha beta t cell activation | GO:0046631 | 91 | 0.405 | |
| interleukin 8 production | GO:0032637 | 4 | 0.401 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.401 | |
| regulation of nitrogen utilization | GO:0006808 | 2 | 0.398 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.396 | |
| jnk cascade | GO:0007254 | 72 | 0.392 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.392 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.390 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.385 | |
| protein catabolic process | GO:0030163 | 221 | 0.380 | |
| regulation of ion transport | GO:0043269 | 215 | 0.380 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.379 | |
| negative regulation of necroptotic process | GO:0060546 | 9 | 0.376 | |
| dendrite development | GO:0016358 | 115 | 0.374 | |
| cellular alcohol biosynthetic process | GO:0044108 | 3 | 0.372 | |
| positive regulation of antimicrobial peptide biosynthetic process | GO:0002807 | 1 | 0.369 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.367 | |
| regulation of cell morphogenesis involved in differentiation | GO:0010769 | 151 | 0.366 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.364 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.359 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.357 | |
| marginal zone b cell differentiation | GO:0002315 | 2 | 0.355 | |
| regulation of tight junction assembly | GO:2000810 | 2 | 0.355 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.353 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.350 | |
| immune response regulating signaling pathway | GO:0002764 | 125 | 0.348 | |
| leukocyte activation involved in immune response | GO:0002366 | 126 | 0.344 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.344 | |
| regulation of interleukin 8 production | GO:0032677 | 3 | 0.343 | |
| t cell differentiation | GO:0030217 | 174 | 0.341 | |
| response to oxidative stress | GO:0006979 | 123 | 0.341 | Fly |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.334 | Human |
| regulation of binding | GO:0051098 | 111 | 0.333 | |
| circulatory system process | GO:0003013 | 197 | 0.331 | |
| pattern recognition receptor signaling pathway | GO:0002221 | 47 | 0.329 | |
| regulation of antimicrobial peptide biosynthetic process | GO:0002805 | 1 | 0.329 | |
| response to drug | GO:0042493 | 75 | 0.326 | |
| notch signaling pathway | GO:0007219 | 71 | 0.325 | |
| positive regulation of antimicrobial humoral response | GO:0002760 | 2 | 0.323 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.322 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.320 | |
| gland development | GO:0048732 | 330 | 0.317 | |
| cation transport | GO:0006812 | 399 | 0.315 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.311 | |
| negative regulation of vascular endothelial growth factor receptor signaling pathway | GO:0030948 | 6 | 0.311 | |
| regulation of protein localization to nucleus | GO:1900180 | 60 | 0.310 | Human |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.308 | |
| positive regulation of myeloid leukocyte differentiation | GO:0002763 | 26 | 0.308 | |
| leukocyte homeostasis | GO:0001776 | 79 | 0.307 | |
| negative regulation of ossification | GO:0030279 | 49 | 0.307 | |
| lymphocyte activation involved in immune response | GO:0002285 | 93 | 0.305 | |
| negative regulation of extrinsic apoptotic signaling pathway | GO:2001237 | 45 | 0.304 | |
| cellular calcium ion homeostasis | GO:0006874 | 119 | 0.300 | |
| regulation of cell motility | GO:2000145 | 236 | 0.298 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.297 | |
| negative regulation of alpha beta t cell activation | GO:0046636 | 18 | 0.296 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.296 | |
| extracellular matrix organization | GO:0030198 | 147 | 0.295 | |
| negative regulation of mapk cascade | GO:0043409 | 65 | 0.292 | |
| negative regulation of notch signaling pathway | GO:0045746 | 14 | 0.291 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.290 | |
| negative regulation of interleukin 8 production | GO:0032717 | 1 | 0.290 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.290 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.289 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.288 | |
| positive regulation of map kinase activity | GO:0043406 | 84 | 0.286 | |
| regulation of antimicrobial humoral response | GO:0002759 | 3 | 0.284 | |
| regulation of jnk cascade | GO:0046328 | 62 | 0.284 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.284 | |
| response to reactive oxygen species | GO:0000302 | 56 | 0.278 | |
| protein import | GO:0017038 | 101 | 0.277 | Human |
| regulation of endopeptidase activity | GO:0052548 | 89 | 0.276 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.276 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.276 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.272 | |
| organelle localization | GO:0051640 | 179 | 0.271 | |
| cytokine production | GO:0001816 | 319 | 0.269 | |
| positive regulation of defense response | GO:0031349 | 124 | 0.268 | |
| positive regulation of leukocyte proliferation | GO:0070665 | 73 | 0.268 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 68 | 0.265 | |
| endocytosis | GO:0006897 | 168 | 0.263 | |
| protein processing | GO:0016485 | 163 | 0.262 | |
| regulation of translation | GO:0006417 | 71 | 0.261 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.260 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.260 | |
| lymphocyte anergy | GO:0002249 | 4 | 0.257 | |
| lipid localization | GO:0010876 | 126 | 0.256 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.255 | |
| positive regulation of antimicrobial peptide production | GO:0002225 | 1 | 0.254 | |
| cellular homeostasis | GO:0019725 | 240 | 0.254 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.254 | |
| regulation of ossification | GO:0030278 | 112 | 0.248 | |
| regulation of innate immune response | GO:0045088 | 91 | 0.248 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.246 | |
| intracellular protein transport | GO:0006886 | 204 | 0.243 | Human |
| antimicrobial peptide biosynthetic process | GO:0002777 | 2 | 0.240 | |
| lymphocyte homeostasis | GO:0002260 | 64 | 0.240 | |
| negative regulation of leukocyte proliferation | GO:0070664 | 46 | 0.236 | |
| single organism nuclear import | GO:1902593 | 95 | 0.236 | Human |
| b cell activation | GO:0042113 | 161 | 0.235 | |
| cellular response to light stimulus | GO:0071482 | 19 | 0.235 | |
| regionalization | GO:0003002 | 337 | 0.235 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.234 | Human |
| negative regulation of cellular response to growth factor stimulus | GO:0090288 | 46 | 0.234 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.232 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.232 | |
| positive regulation of cytokine production | GO:0001819 | 174 | 0.229 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.229 | |
| regulation of defense response to virus | GO:0050688 | 18 | 0.228 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 0.226 | Human |
| fatty acid biosynthetic process | GO:0006633 | 41 | 0.226 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.225 | |
| transmembrane transport | GO:0055085 | 412 | 0.223 | |
| positive regulation of immune effector process | GO:0002699 | 107 | 0.222 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.221 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.220 | |
| activation of immune response | GO:0002253 | 138 | 0.219 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.217 | |
| b cell activation involved in immune response | GO:0002312 | 50 | 0.216 | |
| regulation of myeloid leukocyte differentiation | GO:0002761 | 58 | 0.215 | |
| extracellular structure organization | GO:0043062 | 148 | 0.214 | |
| positive regulation of leukocyte differentiation | GO:1902107 | 86 | 0.213 | |
| negative regulation of necrotic cell death | GO:0060547 | 11 | 0.212 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.211 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.209 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.208 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.208 | Human |
| negative regulation of proteolysis | GO:0045861 | 74 | 0.208 | |
| negative regulation of systemic arterial blood pressure | GO:0003085 | 15 | 0.208 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.206 | |
| cellular response to starvation | GO:0009267 | 57 | 0.206 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 143 | 0.203 | |
| negative regulation of protein maturation | GO:1903318 | 79 | 0.202 | |
| maintenance of location | GO:0051235 | 89 | 0.201 | |
| negative regulation of lymphocyte proliferation | GO:0050672 | 45 | 0.201 | |
| negative regulation of lymphocyte activation | GO:0051250 | 91 | 0.201 | |
| regulation of cell activation | GO:0050865 | 289 | 0.200 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.200 | |
| regulation of adaptive immune response | GO:0002819 | 90 | 0.197 | |
| lipid storage | GO:0019915 | 36 | 0.195 | |
| regulation of alpha beta t cell activation | GO:0046634 | 53 | 0.194 | |
| antimicrobial peptide production | GO:0002775 | 2 | 0.191 | |
| regulation of lymphocyte anergy | GO:0002911 | 4 | 0.189 | |
| leukocyte migration | GO:0050900 | 124 | 0.189 | |
| regulation of necroptotic process | GO:0060544 | 10 | 0.187 | |
| chromatin organization | GO:0006325 | 206 | 0.187 | |
| cellular response to abiotic stimulus | GO:0071214 | 56 | 0.185 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.184 | Human |
| regulation of proteasomal protein catabolic process | GO:0061136 | 46 | 0.183 | |
| positive regulation of sodium ion transport | GO:0010765 | 13 | 0.183 | |
| regulation of cd4 positive alpha beta t cell activation | GO:2000514 | 24 | 0.183 | |
| regulation of tumor necrosis factor superfamily cytokine production | GO:1903555 | 50 | 0.181 | |
| mesenchyme development | GO:0060485 | 152 | 0.181 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.178 | |
| intrinsic apoptotic signaling pathway by p53 class mediator | GO:0072332 | 35 | 0.178 | |
| female gamete generation | GO:0007292 | 74 | 0.177 | |
| histone modification | GO:0016570 | 159 | 0.177 | |
| cellular alcohol metabolic process | GO:0044107 | 3 | 0.177 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.176 | |
| positive regulation of innate immune response | GO:0045089 | 80 | 0.175 | |
| production of molecular mediator of immune response | GO:0002440 | 103 | 0.175 | |
| positive regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032436 | 23 | 0.175 | |
| cellular response to biotic stimulus | GO:0071216 | 92 | 0.175 | |
| regulation of protein processing | GO:0070613 | 96 | 0.174 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.172 | |
| protein deacetylation | GO:0006476 | 32 | 0.172 | |
| leukocyte apoptotic process | GO:0071887 | 71 | 0.171 | |
| peptidyl tyrosine modification | GO:0018212 | 145 | 0.171 | |
| positive regulation of lymphocyte anergy | GO:0002913 | 4 | 0.170 | |
| regulation of transporter activity | GO:0032409 | 57 | 0.170 | |
| response to decreased oxygen levels | GO:0036293 | 59 | 0.169 | |
| regulation of antimicrobial peptide production | GO:0002784 | 1 | 0.169 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 127 | 0.169 | |
| extrinsic apoptotic signaling pathway via death domain receptors | GO:0008625 | 34 | 0.167 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.167 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 71 | 0.167 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 56 | 0.166 | |
| positive regulation of production of molecular mediator of immune response | GO:0002702 | 45 | 0.163 | |
| activation of innate immune response | GO:0002218 | 56 | 0.162 | |
| regulation of ketone biosynthetic process | GO:0010566 | 2 | 0.162 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.160 | |
| regulation of ion transmembrane transporter activity | GO:0032412 | 54 | 0.160 | |
| cation homeostasis | GO:0055080 | 212 | 0.159 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.159 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.158 | |
| somatic diversification of immunoglobulins | GO:0016445 | 43 | 0.156 | |
| skeletal system development | GO:0001501 | 356 | 0.156 | |
| positive regulation of protein catabolic process | GO:0045732 | 60 | 0.156 | |
| sterol metabolic process | GO:0016125 | 58 | 0.155 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 61 | 0.154 | Human |
| regulation of organelle organization | GO:0033043 | 289 | 0.153 | Human |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.152 | Human |
| macroautophagy | GO:0016236 | 21 | 0.152 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.151 | |
| regulation of production of molecular mediator of immune response | GO:0002700 | 65 | 0.150 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.150 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.150 | |
| positive regulation of lymphocyte proliferation | GO:0050671 | 70 | 0.149 | |
| response to peptide | GO:1901652 | 136 | 0.149 | |
| humoral immune response | GO:0006959 | 57 | 0.148 | |
| peptidyl serine phosphorylation | GO:0018105 | 74 | 0.147 | |
| regulation of tumor necrosis factor production | GO:0032680 | 49 | 0.146 | |
| placenta development | GO:0001890 | 140 | 0.145 | |
| developmental maturation | GO:0021700 | 193 | 0.145 | |
| necroptotic process | GO:0070266 | 21 | 0.145 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.144 | |
| response to starvation | GO:0042594 | 65 | 0.143 | |
| defense response to virus | GO:0051607 | 68 | 0.142 | |
| steroid metabolic process | GO:0008202 | 119 | 0.142 | |
| cell activation involved in immune response | GO:0002263 | 126 | 0.140 | |
| isoprenoid biosynthetic process | GO:0008299 | 9 | 0.140 | |
| regulation of cell migration | GO:0030334 | 219 | 0.140 | |
| stem cell development | GO:0048864 | 219 | 0.140 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.140 | |
| phagocytosis | GO:0006909 | 66 | 0.139 | |
| regulation of cellular response to growth factor stimulus | GO:0090287 | 82 | 0.138 | |
| regulation of b cell activation | GO:0050864 | 81 | 0.138 | |
| regulation of lipid biosynthetic process | GO:0046890 | 54 | 0.138 | |
| regulation of fat cell differentiation | GO:0045598 | 81 | 0.138 | |
| negative regulation of multi organism process | GO:0043901 | 68 | 0.137 | |
| cellular response to external stimulus | GO:0071496 | 88 | 0.137 | |
| positive regulation of peptidyl tyrosine phosphorylation | GO:0050731 | 61 | 0.137 | |
| cell junction organization | GO:0034330 | 77 | 0.137 | |
| positive regulation of adaptive immune response | GO:0002821 | 61 | 0.137 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.137 | |
| quinone biosynthetic process | GO:1901663 | 4 | 0.136 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.136 | |
| interferon gamma production | GO:0032609 | 67 | 0.135 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.135 | Human |
| positive regulation of cellular protein catabolic process | GO:1903364 | 34 | 0.134 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.134 | |
| immunoglobulin mediated immune response | GO:0016064 | 69 | 0.133 | |
| interleukin 11 mediated signaling pathway | GO:0038154 | 2 | 0.133 | |
| cytokine biosynthetic process | GO:0042089 | 68 | 0.132 | |
| regulation of leukocyte mediated immunity | GO:0002703 | 104 | 0.130 | |
| anatomical structure homeostasis | GO:0060249 | 145 | 0.130 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.129 | Human |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.128 | |
| regulation of sodium ion transport | GO:0002028 | 29 | 0.128 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.126 | |
| positive regulation of proteolysis involved in cellular protein catabolic process | GO:1903052 | 31 | 0.126 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.126 | |
| sensory perception | GO:0007600 | 245 | 0.126 | |
| macromolecule deacylation | GO:0098732 | 37 | 0.125 | |
| cd4 positive alpha beta t cell activation | GO:0035710 | 45 | 0.125 | |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 106 | 0.123 | |
| regulation of cyclin dependent protein serine threonine kinase activity | GO:0000079 | 16 | 0.122 | |
| regulation of rna export from nucleus | GO:0046831 | 4 | 0.121 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.121 | |
| t helper cell differentiation | GO:0042093 | 28 | 0.120 | |
| regulation of dna binding | GO:0051101 | 39 | 0.120 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.120 | |
| positive regulation of neuron apoptotic process | GO:0043525 | 25 | 0.119 | |
| response to endoplasmic reticulum stress | GO:0034976 | 53 | 0.119 | |
| amide transport | GO:0042886 | 138 | 0.118 | Human |
| positive regulation of ion transmembrane transporter activity | GO:0032414 | 15 | 0.118 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.116 | |
| response to oxygen levels | GO:0070482 | 62 | 0.116 | |
| heart morphogenesis | GO:0003007 | 178 | 0.116 | |
| sodium ion transport | GO:0006814 | 73 | 0.115 | |
| alpha beta t cell proliferation | GO:0046633 | 21 | 0.114 | |
| translation | GO:0006412 | 93 | 0.113 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.113 | |
| regulation of organ morphogenesis | GO:2000027 | 144 | 0.113 | |
| protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:0042787 | 25 | 0.113 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.112 | |
| camera type eye development | GO:0043010 | 266 | 0.112 | |
| somatic cell dna recombination | GO:0016444 | 51 | 0.112 | |
| trna processing | GO:0008033 | 11 | 0.111 | |
| ribonucleoprotein complex localization | GO:0071166 | 1 | 0.111 | |
| response to nutrient levels | GO:0031667 | 109 | 0.110 | |
| innate immune response | GO:0045087 | 157 | 0.110 | |
| glycerolipid metabolic process | GO:0046486 | 122 | 0.109 | |
| cytokine mediated signaling pathway | GO:0019221 | 115 | 0.109 | |
| regulation of neuron death | GO:1901214 | 134 | 0.109 | |
| regulation of cellular response to oxidative stress | GO:1900407 | 19 | 0.109 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.107 | |
| negative regulation of protein processing | GO:0010955 | 79 | 0.107 | |
| tumor necrosis factor production | GO:0032640 | 50 | 0.107 | |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 0.106 | |
| blood circulation | GO:0008015 | 195 | 0.106 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.106 | |
| release of cytochrome c from mitochondria | GO:0001836 | 23 | 0.106 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.105 | |
| axonal fasciculation | GO:0007413 | 15 | 0.105 | |
| ubiquinone metabolic process | GO:0006743 | 4 | 0.105 | |
| cofactor biosynthetic process | GO:0051188 | 41 | 0.104 | |
| positive regulation of endocytosis | GO:0045807 | 42 | 0.104 | |
| signal transduction in absence of ligand | GO:0038034 | 55 | 0.103 | |
| innate immune response activating signal transduction | GO:0002758 | 50 | 0.102 | |
| regulation of necrotic cell death | GO:0010939 | 13 | 0.102 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.102 | Human |
| dna metabolic process | GO:0006259 | 303 | 0.102 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.101 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.101 | |
| myeloid cell homeostasis | GO:0002262 | 114 | 0.101 | |
| small molecule biosynthetic process | GO:0044283 | 132 | 0.100 | |
| positive regulation of cytokine biosynthetic process | GO:0042108 | 40 | 0.100 | |
| negative regulation of immune effector process | GO:0002698 | 55 | 0.099 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.099 | |
| morphogenesis of a branching epithelium | GO:0061138 | 193 | 0.099 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.099 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.098 | |
| negative regulation of leukocyte differentiation | GO:1902106 | 51 | 0.098 | |
| regulation of neuron apoptotic process | GO:0043523 | 122 | 0.098 | |
| regulation of humoral immune response | GO:0002920 | 22 | 0.098 | |
| regulation of isoprenoid metabolic process | GO:0019747 | 1 | 0.097 | |
| regulation of endocytosis | GO:0030100 | 69 | 0.097 | |
| peptide biosynthetic process | GO:0043043 | 11 | 0.097 | |
| multicellular organism growth | GO:0035264 | 161 | 0.097 | |
| regulation of tyrosine phosphorylation of stat1 protein | GO:0042510 | 2 | 0.096 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.096 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 77 | 0.096 | Human |
| covalent chromatin modification | GO:0016569 | 163 | 0.095 | |
| gliogenesis | GO:0042063 | 141 | 0.095 | |
| organic acid biosynthetic process | GO:0016053 | 86 | 0.095 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.094 | Human |
| negative regulation of blood pressure | GO:0045776 | 22 | 0.094 | |
| embryonic placenta development | GO:0001892 | 98 | 0.094 | |
| erk1 and erk2 cascade | GO:0070371 | 77 | 0.094 | |
| regulation of leukocyte apoptotic process | GO:2000106 | 56 | 0.093 | |
| cell recognition | GO:0008037 | 83 | 0.093 | |
| regulation of immunoglobulin mediated immune response | GO:0002889 | 37 | 0.093 | |
| locomotory behavior | GO:0007626 | 195 | 0.092 | |
| cellular response to organic cyclic compound | GO:0071407 | 87 | 0.092 | |
| positive regulation of myeloid cell differentiation | GO:0045639 | 43 | 0.091 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.091 | Human |
| regulation of cofactor metabolic process | GO:0051193 | 5 | 0.091 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.091 | |
| antibacterial peptide production | GO:0002778 | 2 | 0.091 | |
| alpha beta t cell differentiation | GO:0046632 | 69 | 0.091 | |
| tolerance induction | GO:0002507 | 14 | 0.090 | |
| regulation of systemic arterial blood pressure | GO:0003073 | 61 | 0.090 | |
| type 2 immune response | GO:0042092 | 23 | 0.090 | |
| protein localization to organelle | GO:0033365 | 185 | 0.090 | Human |
| response to extracellular stimulus | GO:0009991 | 127 | 0.089 | |
| oxidation reduction process | GO:0055114 | 342 | 0.089 | |
| regulation of peptide transport | GO:0090087 | 91 | 0.089 | Human |
| lipopolysaccharide mediated signaling pathway | GO:0031663 | 25 | 0.089 | |
| defense response to gram negative bacterium | GO:0050829 | 28 | 0.088 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.088 | |
| positive regulation of erk1 and erk2 cascade | GO:0070374 | 47 | 0.087 | |
| immunoglobulin production | GO:0002377 | 73 | 0.087 | |
| synapse organization | GO:0050808 | 125 | 0.084 | |
| wound healing | GO:0042060 | 157 | 0.084 | |
| response to topologically incorrect protein | GO:0035966 | 25 | 0.084 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.083 | |
| positive regulation of smooth muscle cell migration | GO:0014911 | 4 | 0.083 | |
| regulation of lymphocyte mediated immunity | GO:0002706 | 84 | 0.083 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.082 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.082 | |
| regulation of osteoblast differentiation | GO:0045667 | 67 | 0.082 | |
| dna damage response signal transduction by p53 class mediator | GO:0030330 | 19 | 0.082 | |
| positive regulation of lymphocyte activation | GO:0051251 | 140 | 0.082 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.082 | Human |
| t cell differentiation in thymus | GO:0033077 | 77 | 0.081 | |
| placenta blood vessel development | GO:0060674 | 31 | 0.081 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.080 | |
| cell division | GO:0051301 | 120 | 0.080 | |
| regulation of blood pressure | GO:0008217 | 93 | 0.080 | |
| response to inorganic substance | GO:0010035 | 96 | 0.080 | |
| positive regulation of endopeptidase activity | GO:0010950 | 43 | 0.080 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.079 | |
| regulation of coenzyme metabolic process | GO:0051196 | 4 | 0.079 | |
| regulation of actin filament based process | GO:0032970 | 99 | 0.079 | |
| gonad development | GO:0008406 | 141 | 0.079 | |
| regulation of peptidyl tyrosine phosphorylation | GO:0050730 | 93 | 0.079 | |
| rna processing | GO:0006396 | 105 | 0.078 | |
| cell junction assembly | GO:0034329 | 52 | 0.078 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.078 | |
| regulation of protein transport | GO:0051223 | 163 | 0.078 | Human |
| germ cell development | GO:0007281 | 185 | 0.078 | |
| regulation of actin cytoskeleton organization | GO:0032956 | 84 | 0.077 | |
| t cell differentiation involved in immune response | GO:0002292 | 30 | 0.077 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.077 | Human |
| organic hydroxy compound biosynthetic process | GO:1901617 | 77 | 0.077 | |
| inflammatory response | GO:0006954 | 244 | 0.077 | |
| coenzyme metabolic process | GO:0006732 | 52 | 0.077 | |
| regulation of secretion | GO:0051046 | 274 | 0.077 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.076 | |
| protein autophosphorylation | GO:0046777 | 61 | 0.076 | |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.076 | |
| cofactor metabolic process | GO:0051186 | 80 | 0.076 | |
| positive regulation of nf kappab transcription factor activity | GO:0051092 | 30 | 0.075 | |
| regulation of interferon gamma production | GO:0032649 | 57 | 0.075 | |
| cellular response to misfolded protein | GO:0071218 | 5 | 0.075 | |
