Mus musculus

139 known processes

Piwil2

piwi-like homolog 2 (Drosophila)

(Aliases: Piwil1l,mili)

Piwil2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna methylation involved in gamete generationGO:0043046150.995
pirna metabolic processGO:0034587120.830
male meiosisGO:0007140370.602
spermatogenesisGO:00072832840.317
pole plasm assemblyGO:000731520.183
Fly
regulation of transpositionGO:001052820.166
Fly
oocyte axis specificationGO:000730920.157
Fly
dna modificationGO:0006304500.132
positive regulation of meiosis iGO:006090350.122
male gamete generationGO:00482322850.121
intracellular mrna localizationGO:000829840.119
Fly
nuclear divisionGO:00002801580.118
macromolecule methylationGO:00434141200.116
meiosis iGO:0007127600.115
regulation of cellular catabolic processGO:00313292420.108
Fly
meiotic cell cycleGO:00513211220.108
macromolecule catabolic processGO:00090572810.106
Fly
dna metabolic processGO:00062593030.105
fertilizationGO:00095661270.104
dna methylationGO:0006306430.102
negative regulation of transpositionGO:001052920.102
Fly
cellular amino acid metabolic processGO:00065201030.098
ion transmembrane transportGO:00342203610.095
transmembrane transportGO:00550854120.092
methylationGO:00322591340.087
synapsisGO:0007129340.087
oocyte anterior posterior axis specificationGO:000731420.087
Fly
meiotic cell cycle processGO:1903046770.084
cellular macromolecule catabolic processGO:00442652060.084
Fly
aromatic compound catabolic processGO:00194392860.082
Fly
germ cell developmentGO:00072811850.082
glycosyl compound metabolic processGO:19016572460.082
gene silencing by rnaGO:0031047190.082
cation transmembrane transportGO:00986552660.080
inorganic cation transmembrane transportGO:00986622070.078
heterocycle catabolic processGO:00467002800.078
Fly
asymmetric stem cell divisionGO:009872230.073
Fly
posttranscriptional gene silencingGO:0016441100.070
Fly
oocyte constructionGO:000730820.069
Fly
nucleotide catabolic processGO:00091662170.069
purine nucleoside metabolic processGO:00422782410.066
inorganic ion transmembrane transportGO:00986602340.065
meiotic nuclear divisionGO:00071261150.063
nucleoside phosphate metabolic processGO:00067533380.061
male germ line stem cell asymmetric divisionGO:004813320.060
Fly
nucleobase containing small molecule metabolic processGO:00550863520.060
protein catabolic processGO:00301632210.056
purine ribonucleotide metabolic processGO:00091502900.056
cellular nitrogen compound catabolic processGO:00442702800.056
Fly
spermatid developmentGO:00072861080.054
Mouse
chromosome organization involved in meiosisGO:0070192390.054
organic cyclic compound catabolic processGO:19013612950.051
Fly
organelle fissionGO:00482851700.051
posttranscriptional gene silencing by rnaGO:0035194100.048
Fly
dna recombinationGO:0006310920.046
Fly
cellular response to lipidGO:00713961450.046
cellular ion homeostasisGO:00068731650.045
purine nucleoside catabolic processGO:00061522050.043
ribose phosphate metabolic processGO:00196932910.043
regulation of membrane potentialGO:00423911920.043
purine containing compound catabolic processGO:00725232130.043
purine ribonucleoside metabolic processGO:00461282410.043
purine ribonucleoside triphosphate metabolic processGO:00092052200.042
nucleotide metabolic processGO:00091173320.042
regulation of cell cycleGO:00517262810.042
cell divisionGO:00513011200.041
purine containing compound metabolic processGO:00725213110.040
ribonucleotide metabolic processGO:00092592910.040
ribonucleoside metabolic processGO:00091192450.040
regulation of secretion by cellGO:19035302490.040
muscle system processGO:00030121410.039
negative regulation of cellular protein metabolic processGO:00322692470.039
purine nucleoside triphosphate metabolic processGO:00091442260.039
apoptotic signaling pathwayGO:00971903060.038
purine nucleotide metabolic processGO:00061633020.038
cation transportGO:00068123990.038
mitotic cell cycle processGO:19030471590.037
Fly
sensory perceptionGO:00076002450.036
anion transportGO:00068201770.036
negative regulation of protein metabolic processGO:00512482820.036
nucleoside metabolic processGO:00091162460.035
germ line stem cell divisionGO:004207820.035
Fly
ribonucleotide catabolic processGO:00092612080.035
cellular homeostasisGO:00197252400.035
regulation of multi organism processGO:00439001110.035
Fly
ribonucleoside catabolic processGO:00424542060.035
regulation of organelle organizationGO:00330432890.034
regulation of cell cycle processGO:00105641600.034
cellular protein catabolic processGO:00442571550.033
cellular response to cytokine stimulusGO:00713451890.033
cation homeostasisGO:00550802120.033
nucleoside triphosphate catabolic processGO:00091432050.033
positive regulation of programmed cell deathGO:00430682180.033
negative regulation of phosphate metabolic processGO:00459361840.033
cellular response to molecule of bacterial originGO:0071219830.033
regulation of translationGO:0006417710.033
negative regulation of cellular component organizationGO:00511291940.032
Zebrafish
protein processingGO:00164851630.032
regulation of reproductive processGO:2000241660.032
Fly
regulation of transferase activityGO:00513382630.032
cellular response to lipopolysaccharideGO:0071222770.031
chromatin organizationGO:00063252060.031
Fly
regulation of system processGO:00440572000.031
positive regulation of cell deathGO:00109422240.031
metal ion homeostasisGO:00550651890.031
purine nucleotide catabolic processGO:00061952110.031
mrna metabolic processGO:0016071840.031
Fly
regulation of secretionGO:00510462740.030
cytoplasmic transportGO:00164822340.030
carbohydrate derivative catabolic processGO:19011362310.030
cellular chemical homeostasisGO:00550822150.030
purine nucleoside triphosphate catabolic processGO:00091462030.030
dna alkylationGO:0006305430.029
peptidyl amino acid modificationGO:00181933360.029
nucleoside catabolic processGO:00091642060.029
purine ribonucleoside triphosphate catabolic processGO:00092071990.029
negative regulation of cell cycleGO:00457861230.028
synaptic transmissionGO:00072683290.028
heterochromatin organizationGO:007082840.028
Fly
response to molecule of bacterial originGO:00022371430.028
regulation of ion transportGO:00432692150.028
exocytosisGO:00068871210.028
nucleoside triphosphate metabolic processGO:00091412300.028
mitotic cell cycleGO:00002781950.027
Fly
gene silencingGO:0016458380.027
mitotic chromosome condensationGO:000707610.027
Fly
ras protein signal transductionGO:0007265770.027
mrna 3 end processingGO:0031124160.027
Fly
rna processingGO:00063961050.027
glycosyl compound catabolic processGO:19016582060.026
male meiosis iGO:0007141160.026
calcium ion transportGO:00068161590.026
purine ribonucleotide catabolic processGO:00091542080.026
cellular ketone metabolic processGO:0042180840.026
intrinsic apoptotic signaling pathwayGO:00971931320.025
ribonucleoside triphosphate metabolic processGO:00091992200.025
protein maturationGO:00516041760.025
steroid metabolic processGO:00082021190.025
intracellular protein transportGO:00068862040.025
negative regulation of phosphorus metabolic processGO:00105631840.025
developmental maturationGO:00217001930.024
Fly
response to lipopolysaccharideGO:00324961280.024
ribonucleoside triphosphate catabolic processGO:00092031990.024
regulation of mitotic cell cycleGO:00073461260.024
reactive oxygen species metabolic processGO:0072593840.024
positive regulation of apoptotic processGO:00430652170.024
posttranscriptional regulation of gene expressionGO:00106081550.024
cellular divalent inorganic cation homeostasisGO:00725031270.024
translationGO:0006412930.024
myeloid leukocyte differentiationGO:00025731190.024
dephosphorylationGO:00163111290.023
mapk cascadeGO:00001652810.023
regulation of transmembrane transportGO:00347621280.023
kidney developmentGO:00018222130.023
modification dependent macromolecule catabolic processGO:00436321330.023
proteolysis involved in cellular protein catabolic processGO:00516031470.023
transmission of nerve impulseGO:0019226760.023
positive regulation of cellular amino acid metabolic processGO:004576430.023
membrane organizationGO:00610242450.022
sodium ion transportGO:0006814730.022
negative regulation of cell proliferationGO:00082852960.022
purine ribonucleoside catabolic processGO:00461302050.022
chromosome segregationGO:0007059480.022
Fly
cellular metal ion homeostasisGO:00068751510.022
regulation of cellular ketone metabolic processGO:0010565660.022
oxidation reduction processGO:00551143420.022
regulation of cell activationGO:00508652890.022
potassium ion transportGO:0006813520.022
action potentialGO:0001508780.022
nucleoside phosphate catabolic processGO:19012922220.022
negative regulation of molecular functionGO:00440922580.022
cellular response to organonitrogen compoundGO:00714171450.021
reactive nitrogen species metabolic processGO:200105700.021
regulation of purine nucleotide metabolic processGO:19005421690.021
regulation of nucleotide metabolic processGO:00061401690.021
organic hydroxy compound metabolic processGO:19016152030.021
organonitrogen compound catabolic processGO:19015652640.021
microtubule based processGO:00070172360.021
glycerophospholipid metabolic processGO:0006650710.021
sperm motilityGO:0030317470.021
male anatomical structure morphogenesisGO:009059840.020
neuronal action potentialGO:0019228540.020
regulation of proteolysisGO:00301621640.020
calcium ion homeostasisGO:00550741270.020
cellular amine metabolic processGO:0044106440.020
regulation of anatomical structure sizeGO:00900661780.020
extrinsic apoptotic signaling pathwayGO:00971911260.020
regulation of protein maturationGO:1903317960.020
ubiquitin dependent protein catabolic processGO:00065111290.020
positive regulation of protein modification processGO:00314012990.020
maternal determination of anterior posterior axis embryoGO:000835820.020
Fly
organophosphate catabolic processGO:00464342320.019
calcium ion transmembrane transportGO:0070588850.019
positive regulation of defense responseGO:00313491240.019
Fly
sulfur compound metabolic processGO:00067901000.019
regulation of ion transmembrane transportGO:00347651190.019
striated muscle contractionGO:0006941450.019
cellular response to biotic stimulusGO:0071216920.019
nucleocytoplasmic transportGO:00069131390.019
regulation of peptide transportGO:0090087910.019
regulation of hydrolase activityGO:00513362460.019
regulation of protein processingGO:0070613960.019
sodium ion transmembrane transportGO:0035725490.019
mitotic sister chromatid segregationGO:0000070140.019
Fly
carbohydrate derivative biosynthetic processGO:19011371830.019
positive regulation of innate immune responseGO:0045089800.018
Fly
multi multicellular organism processGO:00447061090.018
skeletal system developmentGO:00015013560.018
regulation of protein localizationGO:00328802310.018
cellular lipid metabolic processGO:00442553230.018
lipid biosynthetic processGO:00086101790.018
regulation of innate immune responseGO:0045088910.018
Fly
carboxylic acid transportGO:00469421000.018
chromatin modificationGO:00165681870.018
multicellular organismal signalingGO:0035637910.018
regulation of vesicle mediated transportGO:00606271390.018
skin developmentGO:00435882200.018
hormone secretionGO:00468791280.018
defense response to other organismGO:00985421970.018
Fly
regulation of apoptotic signaling pathwayGO:20012331970.018
mesodermal cell migrationGO:000807840.018
mrna processingGO:0006397630.018
Fly
striated muscle tissue developmentGO:00147062930.017
ribonucleoside monophosphate metabolic processGO:0009161800.017
sequestering of metal ionGO:0051238190.017
glycerolipid metabolic processGO:00464861220.017
guanosine containing compound metabolic processGO:19010681440.017
amine metabolic processGO:0009308450.017
circulatory system processGO:00030131970.017
rna 5 end processingGO:000096610.017
t cell activationGO:00421102890.017
regulation of intracellular transportGO:00323861590.017
cellular modified amino acid metabolic processGO:0006575630.017
stem cell developmentGO:00488642190.017
protein modification by small protein conjugation or removalGO:00706472070.017
small gtpase mediated signal transductionGO:0007264970.017
immune effector processGO:00022523210.017
positive regulation of meiosisGO:0045836140.017
cellularizationGO:000734910.016
Fly
innate immune responseGO:00450871570.016
Fly
camera type eye developmentGO:00430102660.016
regulation of cellular amino acid metabolic processGO:000652150.016
negative regulation of protein processingGO:0010955790.016
response to extracellular stimulusGO:00099911270.016
regulation of nucleoside metabolic processGO:00091181300.016
long chain fatty acid importGO:004453920.016
microtubule cytoskeleton organizationGO:00002261570.016
renal system developmentGO:00720012250.016
sequestering of calcium ionGO:0051208180.016
regulation of cell motilityGO:20001452360.016
rna 3 end processingGO:0031123200.016
Fly
potassium ion transmembrane transportGO:0071805430.016
response to inorganic substanceGO:0010035960.016
spermatid differentiationGO:00485151150.016
Mouse
nuclear transportGO:00511691390.016
positive regulation of hydrolase activityGO:00513451480.016
regulation of hormone levelsGO:00108172110.016
response to radiationGO:00093141650.015
negative regulation of proteolysisGO:0045861740.015
rna interferenceGO:001624620.015
Fly
carbohydrate metabolic processGO:00059752300.015
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.015
skeletal muscle organ developmentGO:00605381630.015
regulation of establishment of protein localizationGO:00702011810.015
gene silencing by mirnaGO:0035195100.015
organic acid transportGO:00158491010.015
protein targetingGO:00066051430.015
purine ribonucleoside monophosphate metabolic processGO:0009167800.015
divalent inorganic cation transportGO:00725111780.015
cell type specific apoptotic processGO:00972852680.015
cellular calcium ion homeostasisGO:00068741190.015
organic anion transportGO:00157111370.015
positive regulation of cellular amine metabolic processGO:003324050.015
placenta developmentGO:00018901400.015
mitotic nuclear divisionGO:0007067480.015
Fly
adult locomotory behaviorGO:0008344910.015
maintenance of locationGO:0051235890.015
segmentationGO:0035282930.015
Fly
adult behaviorGO:00305341350.015
regulation of cellular amine metabolic processGO:0033238200.015
amide transportGO:00428861380.015
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decayGO:190015350.015
Fly
modification dependent protein catabolic processGO:00199411330.015
negative regulation of nik nf kappab signalingGO:190122320.015
divalent inorganic cation homeostasisGO:00725071380.014
cellular potassium ion transportGO:0071804430.014
regulation of lymphocyte activationGO:00512492400.014
negative regulation of cellular catabolic processGO:0031330470.014
response to organic cyclic compoundGO:00140701980.014
sister chromatid segregationGO:0000819200.014
Fly
negative regulation of phosphorylationGO:00423261660.014
protein ubiquitinationGO:00165671710.014
leukocyte migrationGO:00509001240.014
positive regulation of nucleotide metabolic processGO:00459811140.014
regulation of reactive oxygen species metabolic processGO:2000377400.014
regulation of lipid metabolic processGO:00192161180.014
nucleoside monophosphate metabolic processGO:0009123850.014
purine nucleoside monophosphate metabolic processGO:0009126810.014
regulation of tube sizeGO:0035150570.014
blood circulationGO:00080151950.014
regulation of homeostatic processGO:00328441820.014
regulation of cellular protein catabolic processGO:1903362610.014
muscle contractionGO:00069361010.014
regulation of feeding behaviorGO:006025930.014
atp metabolic processGO:0046034750.014
reactive oxygen species biosynthetic processGO:190340980.014
regulation of defense responseGO:00313472330.014
Fly
nitrogen compound transportGO:00717052710.014
negative regulation of organelle organizationGO:0010639900.014
regulation of phospholipid biosynthetic processGO:007107130.013
oocyte maturationGO:0001556180.013
Fly
protein modification by small protein conjugationGO:00324461870.013
regulation of cytoplasmic transportGO:19036491120.013
inflammatory responseGO:00069542440.013
negative regulation of protein maturationGO:1903318790.013
regulation of leukocyte differentiationGO:19021051590.013
negative regulation of hydrolase activityGO:0051346710.013
positive regulation of kinase activityGO:00336741550.013
organonitrogen compound biosynthetic processGO:19015661920.013
response to acid chemicalGO:00011011110.013
divalent metal ion transportGO:00708381720.013
positive regulation of purine nucleotide metabolic processGO:19005441140.013
locomotory behaviorGO:00076261950.013
regulation of leukocyte proliferationGO:00706631210.013
cytosolic calcium ion homeostasisGO:0051480700.013
negative regulation of cell cycle processGO:0010948690.013
response to organonitrogen compoundGO:00102432460.013
sensory organ morphogenesisGO:00905962420.013
protein oligomerizationGO:0051259670.013
protein citrullinationGO:001810120.013
regulation of thyroid hormone generationGO:200060940.013
stem cell differentiationGO:00488632680.013
proteasomal protein catabolic processGO:0010498980.013
positive regulation of mrna metabolic processGO:1903313170.013
Fly
ribonucleoprotein complex subunit organizationGO:0071826280.013
Fly
regulation of mapk cascadeGO:00434082480.013
telencephalon developmentGO:00215371860.013
alpha beta t cell activationGO:0046631910.013
vesicle localizationGO:0051648860.013
positive regulation of mrna processingGO:0050685160.012
Fly
alpha amino acid metabolic processGO:1901605590.012
multicellular organismal homeostasisGO:00488711640.012
regulation of peptide secretionGO:0002791770.012
positive regulation of cellular catabolic processGO:00313311480.012
Fly
organic hydroxy compound transportGO:0015850930.012
regulation of nucleotide catabolic processGO:00308111220.012
rho protein signal transductionGO:0007266320.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
cellular response to dna damage stimulusGO:00069742070.012
regulation of metal ion transportGO:00109591060.012
negative regulation of protein modification processGO:00314001630.012
lipid transportGO:0006869980.012
urogenital system developmentGO:00016552610.012
leukocyte activation involved in immune responseGO:00023661260.012
endomembrane system organizationGO:00102561470.012
synaptic vesicle localizationGO:0097479590.012
positive regulation of monocyte chemotaxisGO:009002620.012
connective tissue developmentGO:00614481790.012
monocarboxylic acid metabolic processGO:00327871910.012
response to light stimulusGO:00094161350.012
muscle fiber developmentGO:0048747760.012
striated muscle cell developmentGO:00550021250.012
germline stem cell asymmetric divisionGO:009872820.012
Fly
negative regulation of nuclear divisionGO:0051784190.012
hematopoietic progenitor cell differentiationGO:00022441430.012
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.012
sa node cell action potentialGO:008601540.012
covalent chromatin modificationGO:00165691630.012
negative regulation of hormone metabolic processGO:003235140.012
leukocyte differentiationGO:00025213420.012
regulation of protein catabolic processGO:00421761080.012
organ growthGO:00352651170.012
positive regulation of reactive oxygen species metabolic processGO:2000379110.012
gtp metabolic processGO:00460391440.012
positive regulation of transferase activityGO:00513471670.012
leukocyte proliferationGO:00706611720.012
anatomical structure homeostasisGO:00602491450.012
attachment of spindle microtubules to kinetochoreGO:000860840.012
negative regulation of gene expression epigeneticGO:0045814150.012
Fly
protein localization to nucleusGO:00345041210.012
detection of abiotic stimulusGO:0009582600.012
regionalizationGO:00030023370.012
Fly
monocarboxylic acid transportGO:0015718440.012
regulation of mitotic cell cycle phase transitionGO:1901990730.011
gtp catabolic processGO:00061841430.011
regulation of blood vessel sizeGO:0050880560.011
regulation of t cell activationGO:00508631700.011
cell activation involved in immune responseGO:00022631260.011
myeloid cell differentiationGO:00300992330.011
muscle tissue developmentGO:00605373080.011
response to amino acidGO:0043200370.011
oocyte differentiationGO:0009994350.011
Fly
negative regulation of cell divisionGO:0051782240.011
regulation of protein kinase activityGO:00458592320.011
oogenesisGO:0048477560.011
regulation of neurotransmitter levelsGO:0001505870.011
establishment of protein localization to organelleGO:00725941180.011
female gamete generationGO:0007292740.011
regulation of fat cell differentiationGO:0045598810.011
regulation of nucleocytoplasmic transportGO:0046822730.011
sensory perception of mechanical stimulusGO:00509541070.011
organic acid biosynthetic processGO:0016053860.011
lymphocyte activation involved in immune responseGO:0002285930.011
regulation of purine nucleotide catabolic processGO:00331211220.011
negative regulation of gene silencingGO:006096920.011
positive regulation of t cell activationGO:00508701010.011
organophosphate biosynthetic processGO:00904071220.011
positive regulation of cell activationGO:00508671580.011
cell maturationGO:00484691270.011
Fly
negative regulation of apoptotic signaling pathwayGO:20012341040.011
epidermis developmentGO:00085441870.011
regulation of transcription by chromatin organizationGO:003440100.011
respiratory system developmentGO:00605411900.011
respiratory tube developmentGO:00303231670.011
regulation of monocyte chemotaxisGO:009002530.011
response to vitamin aGO:003318910.011
cellular response to acid chemicalGO:0071229680.011
endocytosisGO:00068971680.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.011
regulation of protein bindingGO:0043393600.011
response to drugGO:0042493750.011
positive regulation of protein phosphorylationGO:00019342420.011
negative regulation of transferase activityGO:0051348850.010
smooth muscle contractionGO:0006939440.010
positive regulation of cell cycle processGO:0090068610.010
oocyte developmentGO:0048599330.010
Fly
male genitalia morphogenesisGO:004880840.010
glycoprotein metabolic processGO:00091001160.010
establishment of vesicle localizationGO:0051650810.010
rap protein signal transductionGO:003248630.010
development of primary sexual characteristicsGO:00451371430.010
guanosine containing compound catabolic processGO:19010691440.010
peptide transportGO:00158331330.010
alcohol metabolic processGO:00060661160.010
leukocyte mediated immunityGO:00024431740.010
cardiac muscle contractionGO:0060048320.010
regulation of chromosome organizationGO:0033044830.010
positive regulation of nucleotide catabolic processGO:0030813880.010
positive regulation of lymphocyte activationGO:00512511400.010
protein localization to organelleGO:00333651850.010
nucleoside monophosphate catabolic processGO:0009125590.010
alpha beta t cell differentiationGO:0046632690.010
small molecule biosynthetic processGO:00442831320.010
muscle adaptationGO:0043500390.010
regulation of nuclear divisionGO:0051783560.010
positive regulation of purine nucleotide catabolic processGO:0033123880.010
engulfment of apoptotic cellGO:004365230.010
memoryGO:0007613580.010
chromatin silencingGO:0006342150.010
Fly
regulation of organ growthGO:0046620610.010
positive regulation of immune effector processGO:00026991070.010

Piwil2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.029
disease of anatomical entityDOID:700.029
sensory system diseaseDOID:005015500.019
musculoskeletal system diseaseDOID:1700.015
retinal diseaseDOID:567900.013
eye and adnexa diseaseDOID:149200.013
eye diseaseDOID:561400.013