| histone modification | GO:0016570 | 159 | 0.210 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.176 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.171 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.156 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.140 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.138 | |
| axon target recognition | GO:0007412 | 4 | 0.127 | |
| chromatin modification | GO:0016568 | 187 | 0.126 | |
| dna metabolic process | GO:0006259 | 303 | 0.109 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.105 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.105 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.102 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.102 | |
| protein ubiquitination | GO:0016567 | 171 | 0.097 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.096 | |
| negative regulation of transferase activity | GO:0051348 | 85 | 0.094 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.087 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.085 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.084 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.082 | |
| cajal body organization | GO:0030576 | 1 | 0.078 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.072 | |
| rhythmic process | GO:0048511 | 174 | 0.070 | |
| microtubule based process | GO:0007017 | 236 | 0.070 | |
| male gamete generation | GO:0048232 | 285 | 0.065 | |
| gland development | GO:0048732 | 330 | 0.064 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.059 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.057 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.055 | |
| multicellular organism growth | GO:0035264 | 161 | 0.055 | |
| myeloid cell homeostasis | GO:0002262 | 114 | 0.055 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.054 | |
| amine metabolic process | GO:0009308 | 45 | 0.054 | |
| negative regulation of myeloid cell differentiation | GO:0045638 | 38 | 0.053 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.052 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.051 | |
| natural killer cell activation | GO:0030101 | 44 | 0.051 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.051 | |
| neural tube development | GO:0021915 | 160 | 0.050 | |
| chromatin organization | GO:0006325 | 206 | 0.049 | |
| female gamete generation | GO:0007292 | 74 | 0.048 | |
| dna packaging | GO:0006323 | 30 | 0.047 | |
| digestive system development | GO:0055123 | 200 | 0.045 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.044 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.043 | |
| ossification | GO:0001503 | 216 | 0.043 | |
| cytokine production | GO:0001816 | 319 | 0.043 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.042 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.042 | |
| spermatogenesis | GO:0007283 | 284 | 0.039 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.039 | |
| blastocyst development | GO:0001824 | 80 | 0.039 | |
| megakaryocyte differentiation | GO:0030219 | 26 | 0.039 | |
| male sex differentiation | GO:0046661 | 109 | 0.039 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.038 | |
| regulation of chromosome organization | GO:0033044 | 83 | 0.037 | |
| erythrocyte differentiation | GO:0030218 | 88 | 0.036 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.035 | |
| regulation of chromatin modification | GO:1903308 | 57 | 0.035 | |
| cell fate commitment | GO:0045165 | 210 | 0.034 | |
| fat cell differentiation | GO:0045444 | 160 | 0.034 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.034 | |
| epithelial cell development | GO:0002064 | 159 | 0.034 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.033 | |
| mitotic chromosome condensation | GO:0007076 | 1 | 0.033 | |
| signal transduction by p53 class mediator | GO:0072331 | 51 | 0.032 | |
| spermatid development | GO:0007286 | 108 | 0.032 | |
| meiotic cell cycle process | GO:1903046 | 77 | 0.032 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.031 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.031 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.031 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.031 | |
| skeletal system development | GO:0001501 | 356 | 0.031 | |
| oocyte construction | GO:0007308 | 2 | 0.030 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.030 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.030 | |
| respiratory system development | GO:0060541 | 190 | 0.030 | |
| t cell activation | GO:0042110 | 289 | 0.030 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.030 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.029 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.029 | |
| camera type eye development | GO:0043010 | 266 | 0.029 | |
| circulatory system process | GO:0003013 | 197 | 0.028 | |
| regulation of cell activation | GO:0050865 | 289 | 0.028 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.028 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.028 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.027 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.027 | |
| male gonad development | GO:0008584 | 88 | 0.026 | |
| embryonic placenta development | GO:0001892 | 98 | 0.026 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.026 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.026 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.026 | |
| development of primary male sexual characteristics | GO:0046546 | 88 | 0.026 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.026 | |
| protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:0042787 | 25 | 0.026 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.026 | |
| meiosis i | GO:0007127 | 60 | 0.026 | |
| stem cell differentiation | GO:0048863 | 268 | 0.026 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.025 | |
| regulation of system process | GO:0044057 | 200 | 0.025 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.025 | |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.025 | |
| morphogenesis of a branching epithelium | GO:0061138 | 193 | 0.024 | |
| morphogenesis of a branching structure | GO:0001763 | 203 | 0.024 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.024 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.024 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.024 | |
| placenta development | GO:0001890 | 140 | 0.024 | |
| germ cell development | GO:0007281 | 185 | 0.023 | |
| cellular response to lipopolysaccharide | GO:0071222 | 77 | 0.023 | |
| regulation of cell morphogenesis involved in differentiation | GO:0010769 | 151 | 0.023 | |
| chromosome segregation | GO:0007059 | 48 | 0.023 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.022 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.022 | |
| microtubule nucleation | GO:0007020 | 2 | 0.022 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.022 | |
| compound eye development | GO:0048749 | 1 | 0.022 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.022 | |
| natural killer cell differentiation | GO:0001779 | 21 | 0.022 | |
| mrna processing | GO:0006397 | 63 | 0.022 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.022 | |
| dendrite development | GO:0016358 | 115 | 0.022 | |
| endocytosis | GO:0006897 | 168 | 0.021 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.021 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.021 | |
| digestive tract development | GO:0048565 | 190 | 0.021 | |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.021 | |
| mrna metabolic process | GO:0016071 | 84 | 0.021 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.021 | |
| phagocytosis | GO:0006909 | 66 | 0.021 | |
| neuron projection guidance | GO:0097485 | 141 | 0.020 | |
| regulation of defense response | GO:0031347 | 233 | 0.020 | |
| lateral inhibition | GO:0046331 | 1 | 0.020 | |
| respiratory tube development | GO:0030323 | 167 | 0.020 | |
| microtubule polymerization or depolymerization | GO:0031109 | 26 | 0.020 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.020 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.020 | |
| regulation of inflammatory response | GO:0050727 | 147 | 0.020 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.020 | |
| microtubule organizing center organization | GO:0031023 | 28 | 0.020 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.019 | |
| negative regulation of nervous system development | GO:0051961 | 156 | 0.019 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.019 | |
| rna interference | GO:0016246 | 2 | 0.019 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.019 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 48 | 0.019 | |
| nuclear division | GO:0000280 | 158 | 0.019 | |
| canonical wnt signaling pathway | GO:0060070 | 130 | 0.018 | |
| retina development in camera type eye | GO:0060041 | 119 | 0.018 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.018 | |
| regulation of actin cytoskeleton organization | GO:0032956 | 84 | 0.018 | |
| maintenance of location | GO:0051235 | 89 | 0.018 | |
| positive regulation of cell cycle process | GO:0090068 | 61 | 0.018 | |
| chromatin assembly or disassembly | GO:0006333 | 16 | 0.018 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.018 | |
| regulation of neuron death | GO:1901214 | 134 | 0.018 | |
| cellular response to biotic stimulus | GO:0071216 | 92 | 0.018 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.018 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.018 | |
| b cell differentiation | GO:0030183 | 78 | 0.017 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.017 | |
| heart contraction | GO:0060047 | 93 | 0.017 | |
| protein acylation | GO:0043543 | 64 | 0.017 | |
| cellular response to molecule of bacterial origin | GO:0071219 | 83 | 0.017 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.017 | |
| response to peptide | GO:1901652 | 136 | 0.017 | |
| chromatin remodeling at centromere | GO:0031055 | 2 | 0.017 | |
| regulation of secretion | GO:0051046 | 274 | 0.017 | |
| chemotaxis | GO:0006935 | 247 | 0.017 | |
| developmental growth involved in morphogenesis | GO:0060560 | 138 | 0.017 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.017 | |
| inflammatory response | GO:0006954 | 244 | 0.016 | |
| oocyte axis specification | GO:0007309 | 2 | 0.016 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.016 | |
| protein polyubiquitination | GO:0000209 | 33 | 0.016 | |
| spindle assembly involved in female meiosis i | GO:0007057 | 2 | 0.016 | |
| regulation of neuron apoptotic process | GO:0043523 | 122 | 0.016 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 80 | 0.016 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.016 | |
| dna templated transcription termination | GO:0006353 | 4 | 0.016 | |
| innate immune response | GO:0045087 | 157 | 0.016 | |
| activation of immune response | GO:0002253 | 138 | 0.016 | |
| bone development | GO:0060348 | 120 | 0.016 | |
| protein dna complex subunit organization | GO:0071824 | 28 | 0.016 | |
| positive regulation of cytokine production | GO:0001819 | 174 | 0.016 | |
| response to radiation | GO:0009314 | 165 | 0.016 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.015 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.015 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.015 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.015 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.015 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.015 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.015 | |
| spindle assembly involved in meiosis | GO:0090306 | 4 | 0.015 | |
| wound healing | GO:0042060 | 157 | 0.015 | |
| definitive hemopoiesis | GO:0060216 | 20 | 0.015 | |
| leukocyte tethering or rolling | GO:0050901 | 3 | 0.015 | |
| regulation of transforming growth factor beta2 production | GO:0032909 | 2 | 0.015 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.015 | |
| negative regulation of mesenchymal cell proliferation | GO:0072201 | 3 | 0.015 | |
| cellular response to lipid | GO:0071396 | 145 | 0.015 | |
| regulation of osteoblast differentiation | GO:0045667 | 67 | 0.015 | |
| protein methylation | GO:0006479 | 81 | 0.015 | |
| establishment of meiotic spindle orientation | GO:0051296 | 1 | 0.015 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.014 | |
| cellularization | GO:0007349 | 1 | 0.014 | |
| b cell activation | GO:0042113 | 161 | 0.014 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.014 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.014 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.014 | |
| retina morphogenesis in camera type eye | GO:0060042 | 45 | 0.014 | |
| mitotic nuclear division | GO:0007067 | 48 | 0.014 | |
| regulation of myeloid cell differentiation | GO:0045637 | 96 | 0.014 | |
| circadian rhythm | GO:0007623 | 114 | 0.014 | |
| protein secretion | GO:0009306 | 111 | 0.014 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.014 | |
| cell substrate adhesion | GO:0031589 | 130 | 0.014 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.014 | |
| developmental maturation | GO:0021700 | 193 | 0.014 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.014 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.013 | |
| regulation of protein ubiquitination | GO:0031396 | 52 | 0.013 | |
| gonad development | GO:0008406 | 141 | 0.013 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.013 | |
| negative regulation of cell activation | GO:0050866 | 111 | 0.013 | |
| stem cell development | GO:0048864 | 219 | 0.013 | |
| cell division | GO:0051301 | 120 | 0.013 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.013 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 57 | 0.013 | |
| spermatid differentiation | GO:0048515 | 115 | 0.013 | |
| lung development | GO:0030324 | 164 | 0.013 | |
| peptidyl tyrosine modification | GO:0018212 | 145 | 0.013 | |
| skin development | GO:0043588 | 220 | 0.013 | |
| protein catabolic process | GO:0030163 | 221 | 0.013 | |
| blood circulation | GO:0008015 | 195 | 0.013 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.013 | |
| positive regulation of ossification | GO:0045778 | 47 | 0.013 | |
| columnar cuboidal epithelial cell differentiation | GO:0002065 | 82 | 0.013 | |
| regulation of neural precursor cell proliferation | GO:2000177 | 70 | 0.013 | |
| protein polymerization | GO:0051258 | 57 | 0.013 | |
| regulation of hepatocyte proliferation | GO:2000345 | 6 | 0.013 | |
| positive regulation of t cell activation | GO:0050870 | 101 | 0.012 | |
| regulation of ossification | GO:0030278 | 112 | 0.012 | |
| centrosome separation | GO:0051299 | 4 | 0.012 | |
| muscle tissue development | GO:0060537 | 308 | 0.012 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.012 | |
| centrosome organization | GO:0051297 | 26 | 0.012 | |
| mitotic sister chromatid segregation | GO:0000070 | 14 | 0.012 | |
| cell growth | GO:0016049 | 130 | 0.012 | |
| histone acetylation | GO:0016573 | 41 | 0.012 | |
| hindbrain development | GO:0030902 | 128 | 0.012 | |
| defecation | GO:0030421 | 1 | 0.012 | |
| b cell proliferation | GO:0042100 | 53 | 0.012 | |
| response to acid chemical | GO:0001101 | 111 | 0.011 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.011 | |
| regulation of hematopoietic progenitor cell differentiation | GO:1901532 | 18 | 0.011 | |
| cell matrix adhesion | GO:0007160 | 68 | 0.011 | |
| response to insulin | GO:0032868 | 100 | 0.011 | |
| regulation of planar cell polarity pathway involved in axis elongation | GO:2000040 | 3 | 0.011 | |
| regulation of synapse structural plasticity | GO:0051823 | 4 | 0.011 | |
| cellular response to interferon gamma | GO:0071346 | 25 | 0.011 | |
| regulation of leukocyte proliferation | GO:0070663 | 121 | 0.011 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 85 | 0.011 | |
| microtubule polymerization | GO:0046785 | 12 | 0.011 | |
| regulation of chromatin organization | GO:1902275 | 57 | 0.011 | |
| response to peptide hormone | GO:0043434 | 127 | 0.011 | |
| negative regulation of fat cell differentiation | GO:0045599 | 36 | 0.011 | |
| urogenital system development | GO:0001655 | 261 | 0.011 | |
| positive regulation of defense response | GO:0031349 | 124 | 0.011 | |
| gene silencing by rna | GO:0031047 | 19 | 0.011 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.011 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.011 | |
| internal peptidyl lysine acetylation | GO:0018393 | 42 | 0.011 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.011 | |
| maintenance of protein location in nucleus | GO:0051457 | 2 | 0.011 | |
| chromatin assembly | GO:0031497 | 13 | 0.011 | |
| limb development | GO:0060173 | 166 | 0.011 | |
| cytokine mediated signaling pathway | GO:0019221 | 115 | 0.010 | |
| t cell differentiation | GO:0030217 | 174 | 0.010 | |
| positive regulation of cell cycle | GO:0045787 | 92 | 0.010 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.010 | |
| cellular response to insulin stimulus | GO:0032869 | 78 | 0.010 | |
| positive regulation of lymphocyte activation | GO:0051251 | 140 | 0.010 | |
| sertoli cell development | GO:0060009 | 15 | 0.010 | |
| dna recombination | GO:0006310 | 92 | 0.010 | |
| regulation of protein secretion | GO:0050708 | 82 | 0.010 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.010 | |
| negative regulation of response to wounding | GO:1903035 | 77 | 0.010 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.010 | |
| positive regulation of cell activation | GO:0050867 | 158 | 0.010 | |
