Mus musculus

29 known processes

Postn

periostin, osteoblast specific factor

(Aliases: Osf2,OSF-2,peri,PLF,AI747096,A630052E07Rik,PN)

Postn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
proteoglycan metabolic processGO:0006029380.843
cell adhesionGO:00071553290.831
cell substrate adhesionGO:00315891300.783
extracellular matrix organizationGO:00301981470.735
regulation of cell substrate adhesionGO:0010810730.647
ras protein signal transductionGO:0007265770.592
regulation of cell adhesionGO:00301551540.567
extracellular structure organizationGO:00430621480.514
response to growth factorGO:00708481980.434
rho protein signal transductionGO:0007266320.432
regulation of cell migrationGO:00303342190.428
regulation of tooth mineralizationGO:007017020.398
negative regulation of tooth mineralizationGO:007017110.358
telencephalon developmentGO:00215371860.349
glycoprotein metabolic processGO:00091001160.338
negative regulation of cell adhesionGO:0007162450.313
negative regulation of vasculature developmentGO:1901343260.300
pallium developmentGO:00215431200.282
cellular response to growth factor stimulusGO:00713631970.274
negative regulation of blood vessel morphogenesisGO:2000181250.266
cell matrix adhesionGO:0007160680.255
response to transforming growth factor betaGO:0071559880.251
negative regulation of cell substrate adhesionGO:0010812160.247
signal transduction in absence of ligandGO:0038034550.245
forebrain developmentGO:00309003020.241
heart morphogenesisGO:00030071780.240
blood vessel morphogenesisGO:00485142850.236
mineralocorticoid biosynthetic processGO:000670510.232
extrinsic apoptotic signaling pathwayGO:00971911260.219
transforming growth factor beta receptor signaling pathwayGO:0007179710.216
response to organonitrogen compoundGO:00102432460.207
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.204
response to amino acidGO:0043200370.200
regulation of apoptotic signaling pathwayGO:20012331970.200
regulation of angiogenesisGO:0045765810.192
skeletal system developmentGO:00015013560.191
small gtpase mediated signal transductionGO:0007264970.190
regulation of body fluid levelsGO:00508781620.187
negative regulation of apoptotic signaling pathwayGO:20012341040.180
cartilage condensationGO:0001502180.176
sensory perceptionGO:00076002450.168
aminoglycan metabolic processGO:0006022340.166
cerebral cortex developmentGO:0021987860.162
limb developmentGO:00601731660.144
connective tissue developmentGO:00614481790.138
angiogenesisGO:00015252010.133
cardiac muscle tissue developmentGO:00487381300.132
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.131
sensory perception of mechanical stimulusGO:00509541070.130
regulation of cell motilityGO:20001452360.126
negative regulation of cell developmentGO:00107211690.124
negative regulation of hydrolase activityGO:0051346710.123
cellular response to amino acid stimulusGO:0071230290.120
peptide cross linkingGO:0018149100.112
cardiac chamber morphogenesisGO:0003206930.111
regulation of hydrolase activityGO:00513362460.108
sensory perception of soundGO:0007605970.107
limb bud formationGO:0060174100.106
positive regulation of cellular amino acid metabolic processGO:004576430.103
inner ear morphogenesisGO:00424721010.102
regulation of ras protein signal transductionGO:00465781140.102
gastrulationGO:00073691160.101
digestive tract developmentGO:00485651900.097
negative regulation of cell motilityGO:2000146610.096
sensory organ morphogenesisGO:00905962420.094
regulation of rho protein signal transductionGO:0035023710.094
peptidyl amino acid modificationGO:00181933360.093
embryonic organ morphogenesisGO:00485622760.093
cellular response to external stimulusGO:0071496880.089
anatomical structure homeostasisGO:00602491450.088
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.088
tissue homeostasisGO:00018941150.085
protein heterooligomerizationGO:0051291140.085
response to organic cyclic compoundGO:00140701980.084
multicellular organismal homeostasisGO:00488711640.084
regulation of peptidase activityGO:0052547960.082
trabecula formationGO:0060343240.082
negative regulation of cell proliferationGO:00082852960.082
ear morphogenesisGO:00424711180.081
extracellular fibril organizationGO:004320620.080
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.079
response to acid chemicalGO:00011011110.078
positive regulation of cell substrate adhesionGO:0010811470.078
fibril organizationGO:009743520.078
cardiac chamber developmentGO:00032051080.077
negative regulation of nervous system developmentGO:00519611560.076
single organism cell adhesionGO:00986021560.075
positive regulation of cell adhesionGO:0045785800.075
apoptotic signaling pathwayGO:00971903060.073
negative regulation of signal transduction in absence of ligandGO:1901099160.070
regulation of actin cytoskeleton organizationGO:0032956840.068
ear developmentGO:00435832000.068
aorta morphogenesisGO:0035909220.067
blood circulationGO:00080151950.066
negative regulation of angiogenesisGO:0016525250.066
regulation of organ morphogenesisGO:20000271440.065
positive regulation of cell migrationGO:00303351090.065
skeletal system morphogenesisGO:00487052030.064
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.064
chondrocyte differentiationGO:0002062720.063
cardiac ventricle developmentGO:0003231830.063
chondroitin sulfate metabolic processGO:0030204170.062
bone trabecula formationGO:006034690.062
response to radiationGO:00093141650.062
bone trabecula morphogenesisGO:0061430120.061
renal system developmentGO:00720012250.060
regulation of protein kinase activityGO:00458592320.060
artery developmentGO:0060840530.059
asymmetric stem cell divisionGO:009872230.059
cartilage development involved in endochondral bone morphogenesisGO:0060351240.058
neuron migrationGO:00017641220.058
hair cycleGO:0042633900.057
aorta smooth muscle tissue morphogenesisGO:006041420.057
embryonic skeletal system morphogenesisGO:0048704910.057
protein oligomerizationGO:0051259670.057
muscle tissue developmentGO:00605373080.057
cellular response to organonitrogen compoundGO:00714171450.056
chondrocyte developmentGO:0002063240.056
bone developmentGO:00603481200.056
chondroitin sulfate proteoglycan metabolic processGO:0050654200.056
wound healingGO:00420601570.055
cellular amine metabolic processGO:0044106440.054
regulation of cellular ketone metabolic processGO:0010565660.053
cardiac ventricle morphogenesisGO:0003208500.053
skin developmentGO:00435882200.053
retinal blood vessel morphogenesisGO:006130430.051
positive regulation of hydrolase activityGO:00513451480.051
regulation of neuron projection developmentGO:00109751690.051
head morphogenesisGO:0060323340.049
glycosaminoglycan metabolic processGO:0030203340.048
embryonic skeletal system developmentGO:00487061200.048
peptidyl serine modificationGO:0018209830.048
positive regulation of ras protein signal transductionGO:0046579130.047
regulation of extent of cell growthGO:0061387520.047
neuromuscular processGO:0050905990.047
sulfur compound metabolic processGO:00067901000.047
circulatory system processGO:00030131970.046
jnk cascadeGO:0007254720.046
regulation of neuron migrationGO:2001222220.046
regulation of map kinase activityGO:00434051200.045
striated muscle tissue developmentGO:00147062930.044
single organismal cell cell adhesionGO:00163371310.044
regulation of proteolysisGO:00301621640.044
negative regulation of odontogenesisGO:004248330.043
negative regulation of phospholipase activityGO:001051940.042
peptide cross linking via chondroitin 4 sulfate glycosaminoglycanGO:001980080.042
nephron developmentGO:00720061090.042
cellular chemical homeostasisGO:00550822150.042
response to peptide hormoneGO:00434341270.042
digestive tract morphogenesisGO:00485461470.041
digestive system developmentGO:00551232000.040
ameboidal type cell migrationGO:00016671280.040
cellular amino acid metabolic processGO:00065201030.039
cellular response to transforming growth factor beta stimulusGO:0071560880.039
palate developmentGO:0060021760.039
protein trimerizationGO:0070206130.038
regulation of macrophage migration inhibitory factor signaling pathwayGO:200044610.038
monocarboxylic acid metabolic processGO:00327871910.038
notochord developmentGO:0030903200.038
generation of precursor metabolites and energyGO:00060911030.038
positive regulation of cell projection organizationGO:0031346950.038
substrate adhesion dependent cell spreadingGO:0034446300.037
ventricular cardiac muscle tissue morphogenesisGO:0055010320.037
oxidation reduction processGO:00551143420.037
trabecula morphogenesisGO:0061383400.036
clathrin coat assemblyGO:004826820.036
positive regulation of dna templated transcription elongationGO:003278620.035
negative regulation of cellular component organizationGO:00511291940.035
organonitrogen compound biosynthetic processGO:19015661920.035
cartilage developmentGO:00512161400.035
cellular response to hormone stimulusGO:00328701500.034
regulation of cellular component biogenesisGO:00440871810.034
stress activated protein kinase signaling cascadeGO:0031098810.033
negative regulation of epithelial cell proliferationGO:0050680640.032
negative regulation of molecular functionGO:00440922580.032
protein processingGO:00164851630.032
regulation of protein bindingGO:0043393600.032
endomembrane system organizationGO:00102561470.031
cell aggregationGO:0098743180.031
response to lipopolysaccharideGO:00324961280.031
mucopolysaccharide metabolic processGO:1903510250.031
establishment or maintenance of cell polarityGO:0007163860.031
forebrain cell migrationGO:0021885580.031
negative regulation of cell migrationGO:0030336590.030
response to monosaccharideGO:0034284670.030
cellular ketone metabolic processGO:0042180840.030
cardiac muscle tissue morphogenesisGO:0055008440.030
lipid localizationGO:00108761260.030
aorta developmentGO:0035904230.029
camera type eye developmentGO:00430102660.029
acylglycerol metabolic processGO:0006639550.029
epithelial cell proliferationGO:00506731740.029
wnt signaling pathwayGO:00160551880.028
endoderm formationGO:0001706200.028
appendage developmentGO:00487361660.028
tooth mineralizationGO:003450590.028
response to catecholamineGO:007186940.028
regionalizationGO:00030023370.028
regulation of cellular amino acid metabolic processGO:000652150.028
protein heterotrimerizationGO:007020880.028
response to molecule of bacterial originGO:00022371430.027
hair follicle morphogenesisGO:0031069290.027
muscle tissue morphogenesisGO:0060415530.027
epithelium migrationGO:0090132630.027
fat cell differentiationGO:00454441600.027
cytoplasmic transportGO:00164822340.026
innate immune responseGO:00450871570.026
kidney developmentGO:00018222130.026
amine metabolic processGO:0009308450.026
positive regulation of proteolysisGO:0045862850.026
negative regulation of protein activation cascadeGO:200025830.026
glucose homeostasisGO:00425931280.026
microtubule cytoskeleton organizationGO:00002261570.026
actin cytoskeleton organizationGO:00300362200.025
positive regulation of cellular amine metabolic processGO:003324050.025
nuclear transportGO:00511691390.025
regulation of cellular amine metabolic processGO:0033238200.025
heart processGO:0003015940.025
positive regulation of protein phosphorylationGO:00019342420.025
face morphogenesisGO:0060325290.024
plasma membrane organizationGO:0007009900.024
response to nutrient levelsGO:00316671090.024
physiological cardiac muscle hypertrophyGO:000330130.024
regulation of cell growth involved in cardiac muscle cell developmentGO:006105030.024
retina development in camera type eyeGO:00600411190.024
engulfment of apoptotic cellGO:004365230.024
myeloid leukocyte migrationGO:0097529570.023
positive regulation of endothelial cell migrationGO:0010595120.023
response to inorganic substanceGO:0010035960.023
lipid homeostasisGO:0055088630.023
positive regulation of rho protein signal transductionGO:003502570.023
odontogenesisGO:0042476780.023
smooth muscle tissue developmentGO:0048745220.023
regulation of neuron apoptotic processGO:00435231220.023
nucleoside phosphate metabolic processGO:00067533380.023
cellular homeostasisGO:00197252400.023
cellular lipid metabolic processGO:00442553230.023
ossificationGO:00015032160.022
regulation of mapk cascadeGO:00434082480.022
regulation of cell sizeGO:0008361720.022
cellular nitrogen compound catabolic processGO:00442702800.022
alcohol metabolic processGO:00060661160.022
positive regulation of cellular component biogenesisGO:0044089940.022
response to extracellular stimulusGO:00099911270.021
regulation of system processGO:00440572000.021
organophosphate biosynthetic processGO:00904071220.021
regulation of cytoplasmic transportGO:19036491120.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.021
glucan metabolic processGO:0044042320.021
regulation of inflammatory responseGO:00507271470.021
mapk cascadeGO:00001652810.021
regulation of cysteine type endopeptidase activityGO:2000116650.021
vascular process in circulatory systemGO:0003018620.021
hair follicle developmentGO:0001942850.020
cellular response to organic cyclic compoundGO:0071407870.020
energy derivation by oxidation of organic compoundsGO:0015980770.020
developmental cell growthGO:0048588840.020
negative regulation of neuron migrationGO:200122360.020
ventricular cardiac muscle tissue developmentGO:0003229380.020
regulation of epithelial cell migrationGO:0010632350.020
integrin mediated signaling pathwayGO:0007229270.020
calcium ion transportGO:00068161590.020
cellular response to abiotic stimulusGO:0071214560.020
regulation of lipid transportGO:0032368360.020
reactive oxygen species biosynthetic processGO:190340980.020
telencephalon cell migrationGO:0022029550.020
cellular response to acid chemicalGO:0071229680.019
positive regulation of cell motilityGO:20001471160.019
vesicle organizationGO:0016050600.019
g protein coupled receptor signaling pathwayGO:00071862430.019
respiratory tube developmentGO:00303231670.019
protein localization to plasma membraneGO:0072659570.019
regulation of endodermal cell differentiationGO:190322420.019
mesenchymal cell developmentGO:0014031930.018
protein maturationGO:00516041760.018
response to peptideGO:19016521360.018
negative regulation of protein localization to plasma membraneGO:190307750.018
carbohydrate metabolic processGO:00059752300.018
formation of primary germ layerGO:0001704770.018
replacement ossificationGO:0036075260.018
membrane organizationGO:00610242450.018
tissue remodelingGO:00487711020.018
developmental growth involved in morphogenesisGO:00605601380.018
cellular response to cytokine stimulusGO:00713451890.017
positive regulation of protein modification processGO:00314012990.017
regulation of bindingGO:00510981110.017
immune effector processGO:00022523210.017
organic hydroxy compound metabolic processGO:19016152030.017
muscle system processGO:00030121410.017
regulation of cytokine secretion involved in immune responseGO:000273940.017
response to alcoholGO:0097305480.017
maintenance of locationGO:0051235890.017
negative regulation of complement activationGO:004591630.017
heart contractionGO:0060047930.016
regulation of cellular response to growth factor stimulusGO:0090287820.016
collagen fibril organizationGO:0030199320.016
regulation of peptidyl tyrosine phosphorylationGO:0050730930.016
canonical wnt signaling pathwayGO:00600701300.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.016
regulation of endopeptidase activityGO:0052548890.016
metal ion homeostasisGO:00550651890.016
cellular response to lipidGO:00713961450.016
cell growth involved in cardiac muscle cell developmentGO:006104930.016
skeletal muscle organ developmentGO:00605381630.016
Zebrafish
negative regulation of proteolysisGO:0045861740.016
negative regulation of phosphorylationGO:00423261660.016
endocytosisGO:00068971680.016
protein targetingGO:00066051430.016
regulation of cytokine productionGO:00018172660.016
cell type specific apoptotic processGO:00972852680.016
regulation of vasculature developmentGO:1901342880.016
cellular divalent inorganic cation homeostasisGO:00725031270.015
neurotransmitter catabolic processGO:004213530.015
response to epidermal growth factorGO:007084940.015
regulation of protein transportGO:00512231630.015
hormone metabolic processGO:0042445860.015
positive regulation of growthGO:00459271040.015
nuclear importGO:0051170950.015
cellular response to vitaminGO:007129520.015
negative regulation of neuron projection developmentGO:0010977500.015
regulation of cell growthGO:0001558910.015
regulation of odontogenesisGO:0042481180.015
limb morphogenesisGO:00351081490.015
synapse organizationGO:00508081250.015
positive regulation of cell growthGO:0030307330.015
cardiac cell developmentGO:0055006410.014
positive regulation of kinase activityGO:00336741550.014
nitrogen compound transportGO:00717052710.014
regulation of secretion by cellGO:19035302490.014
nucleocytoplasmic transportGO:00069131390.014
divalent inorganic cation homeostasisGO:00725071380.014
negative regulation of endothelial cell proliferationGO:000193780.014
appendage morphogenesisGO:00351071490.014
branching morphogenesis of an epithelial tubeGO:00487541590.014
notochord cell differentiationGO:006003410.014
ribose phosphate metabolic processGO:00196932910.014
positive regulation of apoptotic signaling pathwayGO:2001235950.014
endochondral bone morphogenesisGO:0060350500.014
regulation of neuron differentiationGO:00456642810.014
regulation of establishment of protein localizationGO:00702011810.014
negative regulation of cell proliferation involved in contact inhibitionGO:006024430.014
peptidyl tyrosine phosphorylationGO:00181081430.014
cellular glucan metabolic processGO:0006073320.014
positive regulation of neuron projection developmentGO:0010976790.013
positive regulation of cell deathGO:00109422240.013
neuron deathGO:00709971540.013
small molecule biosynthetic processGO:00442831320.013
cellular carbohydrate metabolic processGO:00442621190.013
neuromuscular process controlling balanceGO:0050885590.013
response to defense related host nitric oxide productionGO:005256520.013
protein import into nucleusGO:0006606950.013
synaptic transmission cholinergicGO:000727170.013
positive regulation of cardiac muscle contractionGO:006045220.013
cell adhesion mediated by integrinGO:0033627180.013
lung developmentGO:00303241640.013
regulation of intracellular transportGO:00323861590.013
regulation of wnt signaling pathwayGO:00301111230.012
endoderm developmentGO:0007492450.012
regulation of protein localizationGO:00328802310.012
glycogen metabolic processGO:0005977320.012
cellular calcium ion homeostasisGO:00068741190.012
positive regulation of cytosolic calcium ion concentrationGO:0007204650.012
regulation of purine nucleotide metabolic processGO:19005421690.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
regulation of jnk cascadeGO:0046328620.012
granulocyte migrationGO:0097530430.012
developmental maturationGO:00217001930.012
posttranscriptional regulation of gene expressionGO:00106081550.012
positive regulation of hormone metabolic processGO:003235230.012
negative regulation of phosphorus metabolic processGO:00105631840.012
positive regulation of programmed cell deathGO:00430682180.012
regulation of sphingolipid biosynthetic processGO:009015310.012
molting cycleGO:0042303900.012
morphogenesis of a branching epitheliumGO:00611381930.012
cytokine productionGO:00018163190.012
protein catabolic processGO:00301632210.012
negative regulation of lipase activityGO:006019270.012
negative regulation of cellular protein metabolic processGO:00322692470.012
regulation of nucleocytoplasmic transportGO:0046822730.012
physiological muscle hypertrophyGO:000329830.012
regulation of organelle organizationGO:00330432890.012
sequestering of calcium ionGO:0051208180.012
negative regulation of camp mediated signalingGO:004395130.012
regulation of biomineral tissue developmentGO:0070167330.012
cellularizationGO:000734910.012
positive regulation of camp mediated signalingGO:004395030.011
respiratory system developmentGO:00605411900.011
negative regulation of embryonic developmentGO:0045992220.011
compound eye developmentGO:004874910.011
regulation of ceramide biosynthetic processGO:200030310.011
macromolecule catabolic processGO:00090572810.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
sensory system developmentGO:004888030.011
cardiocyte differentiationGO:0035051870.011
response to thyroid hormoneGO:009706620.011
trunk segmentationGO:003529040.011
response to starvationGO:0042594650.011
positive regulation of cytokine productionGO:00018191740.011
regulation of lipase activityGO:0060191150.011
regulation of cell projection organizationGO:00313442060.011
regulation of stress activated mapk cascadeGO:0032872690.011
regulation of hormone levelsGO:00108172110.011
carbohydrate derivative biosynthetic processGO:19011371830.011
cardiac muscle cell differentiationGO:0055007690.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.011
organelle localizationGO:00516401790.011
regulation of protein secretionGO:0050708820.011
phagocytosisGO:0006909660.011
peptidyl tyrosine modificationGO:00182121450.011
homeostasis of number of cellsGO:00488722100.011
negative regulation of cell morphogenesis involved in differentiationGO:0010771480.011
endothelial cell migrationGO:0043542440.011
multicellular organismal signalingGO:0035637910.011
regulation of intracellular protein transportGO:0033157820.011
endodermal cell differentiationGO:0035987140.011
hormone secretionGO:00468791280.011
purine containing compound metabolic processGO:00725213110.011
response to endoplasmic reticulum stressGO:0034976530.011
otic vesicle developmentGO:0071599140.011
tissue migrationGO:0090130680.011
single organism nuclear importGO:1902593950.010
response to reactive oxygen speciesGO:0000302560.010
purine nucleotide metabolic processGO:00061633020.010
regulation of blood pressureGO:0008217930.010
cellular component assembly involved in morphogenesisGO:00109271390.010
placenta developmentGO:00018901400.010
regulation of cell cycleGO:00517262810.010
cation transportGO:00068123990.010
mesenchyme developmentGO:00604851520.010
myeloid leukocyte differentiationGO:00025731190.010
positive regulation of vesicle fusionGO:003134020.010
dna metabolic processGO:00062593030.010
anion transportGO:00068201770.010
long chain fatty acid importGO:004453920.010
cell growthGO:00160491300.010
cardiac muscle contractionGO:0060048320.010
trunk neural crest cell migrationGO:003648440.010
fibrinolysisGO:004273030.010
skin morphogenesisGO:0043589380.010
positive regulation of lipid metabolic processGO:0045834400.010
positive regulation of peptidyl serine phosphorylationGO:0033138250.010
protein localization to nucleusGO:00345041210.010
synaptic transmissionGO:00072683290.010
otolith morphogenesisGO:003247430.010
regulation of protein serine threonine kinase activityGO:00719001570.010

Postn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
connective tissue diseaseDOID:6500.368
musculoskeletal system diseaseDOID:1700.368
disease of anatomical entityDOID:700.368
myopathyDOID:42300.253
muscular diseaseDOID:008000000.253
muscle tissue diseaseDOID:6600.253
collagen diseaseDOID:85400.132
ehlers danlos syndromeDOID:1335900.058
muscular dystrophyDOID:988400.058
congenital muscular dystrophyDOID:005055700.058
nervous system diseaseDOID:86300.031
immune system diseaseDOID:291400.022
bone diseaseDOID:008000100.020
osteochondrodysplasiaDOID:225600.020
bone development diseaseDOID:008000600.020
osteoporosisDOID:1147600.011
bone remodeling diseaseDOID:008000500.011
bone resorption diseaseDOID:008001100.011
cardiomyopathyDOID:005070000.011
intrinsic cardiomyopathyDOID:006003600.011
heart diseaseDOID:11400.011
cardiovascular system diseaseDOID:128700.011