Mus musculus

72 known processes

Mre11a

meiotic recombination 11 homolog A (S. cerevisiae)

(Aliases: Mre11b,Mre11)

Mre11a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.769
dna repairGO:00062811070.451
double strand break repairGO:0006302480.392
telomere cappingGO:001623340.359
Fly
meiotic cell cycle processGO:1903046770.285
nuclear divisionGO:00002801580.228
mitotic cell cycle processGO:19030471590.175
meiotic cell cycleGO:00513211220.172
regulation of protein autophosphorylationGO:003195280.163
Human
telomere maintenanceGO:0000723190.159
Fly
organelle fissionGO:00482851700.155
dna replicationGO:0006260520.149
Human
mitotic recombinationGO:000631230.148
microtubule based processGO:00070172360.138
chromosome organization involved in meiosisGO:0070192390.136
dna conformation changeGO:0071103370.126
Human
synapsisGO:0007129340.125
anatomical structure homeostasisGO:00602491450.115
Fly
cellular hyperosmotic salinity responseGO:007147500.115
dna recombinationGO:0006310920.110
Yeast
heterocycle catabolic processGO:00467002800.095
Human Yeast
negative regulation of cell cycleGO:00457861230.093
aromatic compound catabolic processGO:00194392860.090
Human Yeast
microtubule organizing center organizationGO:0031023280.084
somatic recombination of immunoglobulin gene segmentsGO:0016447420.078
positive regulation of protein phosphorylationGO:00019342420.073
Human
microtubule cytoskeleton organizationGO:00002261570.071
chromosome segregationGO:0007059480.067
Human Worm
positive regulation of protein modification processGO:00314012990.066
Human
rna dependent dna replicationGO:000627830.065
organic cyclic compound catabolic processGO:19013612950.063
Human Yeast
dna duplex unwindingGO:003250870.060
Human
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.058
cellular amino acid metabolic processGO:00065201030.056
cellular macromolecule catabolic processGO:00442652060.055
Yeast
regulation of transferase activityGO:00513382630.055
Human
organelle assemblyGO:00709251770.055
regulation of mitotic cell cycleGO:00073461260.053
cellular nitrogen compound catabolic processGO:00442702800.050
Human Yeast
cellular response to dna damage stimulusGO:00069742070.047
nuclear transportGO:00511691390.046
mitotic cell cycleGO:00002781950.045
negative regulation of cell cycle processGO:0010948690.044
cytoplasmic transportGO:00164822340.042
nucleic acid phosphodiester bond hydrolysisGO:0090305490.040
Yeast
somatic cell dna recombinationGO:0016444510.039
meiotic nuclear divisionGO:00071261150.039
nuclear dna replicationGO:003326030.039
regulation of cell cycleGO:00517262810.038
gene silencingGO:0016458380.038
establishment of organelle localizationGO:00516561220.038
chromatin organizationGO:00063252060.038
negative regulation of mitotic cell cycleGO:0045930580.037
mitotic nuclear divisionGO:0007067480.036
regulation of cell cycle processGO:00105641600.035
meiosis iGO:0007127600.035
apoptotic signaling pathwayGO:00971903060.034
organelle localizationGO:00516401790.033
peptidyl amino acid modificationGO:00181933360.033
blastocyst developmentGO:0001824800.032
regulation of organelle organizationGO:00330432890.032
regulation of cellular ketone metabolic processGO:0010565660.032
response to x rayGO:0010165110.032
reciprocal dna recombinationGO:0035825160.032
Yeast
cellular ketone metabolic processGO:0042180840.032
nucleocytoplasmic transportGO:00069131390.031
positive regulation of protein autophosphorylationGO:003195440.030
Human
intracellular protein transportGO:00068862040.030
ribose phosphate metabolic processGO:00196932910.029
Human
telomere maintenance via telomeraseGO:000700410.029
organonitrogen compound catabolic processGO:19015652640.028
Human
negative regulation of cellular component organizationGO:00511291940.028
cellular amine metabolic processGO:0044106440.027
cell cycle checkpointGO:0000075470.026
dna geometric changeGO:003239270.026
Human
positive regulation of hydrolase activityGO:00513451480.026
endocytosisGO:00068971680.026
nucleobase containing small molecule metabolic processGO:00550863520.025
Human Yeast
glycosyl compound metabolic processGO:19016572460.025
Human
somatic diversification of immunoglobulinsGO:0016445430.025
cell activation involved in immune responseGO:00022631260.025
purine ribonucleoside triphosphate catabolic processGO:00092071990.024
Human
regulation of protein localizationGO:00328802310.024
synaptonemal complex assemblyGO:0007130130.024
regulation of mitotic cell cycle phase transitionGO:1901990730.024
posttranscriptional regulation of gene expressionGO:00106081550.024
regulation of cellular amino acid metabolic processGO:000652150.024
macromolecule catabolic processGO:00090572810.023
Yeast
regulation of cytoskeleton organizationGO:00514931220.023
spindle assembly involved in mitosisGO:009030740.023
protein autophosphorylationGO:0046777610.023
Human
chemotaxisGO:00069352470.023
positive regulation of cellular amino acid metabolic processGO:004576430.022
positive regulation of kinase activityGO:00336741550.022
Human
ribonucleotide metabolic processGO:00092592910.022
Human
amine metabolic processGO:0009308450.022
positive regulation of transferase activityGO:00513471670.022
Human
regulation of dna recombinationGO:0000018340.021
immunoglobulin productionGO:0002377730.021
carbohydrate derivative biosynthetic processGO:19011371830.021
regulation of cell cycle phase transitionGO:1901987770.021
positive regulation of cellular amine metabolic processGO:003324050.021
intrinsic apoptotic signaling pathwayGO:00971931320.021
immune effector processGO:00022523210.021
organophosphate catabolic processGO:00464342320.020
Human
methylationGO:00322591340.020
non recombinational repairGO:0000726100.020
Yeast
establishment of protein localization to organelleGO:00725941180.020
dna catabolic process endonucleolyticGO:0000737150.020
Yeast
protein importGO:00170381010.020
mrna processingGO:0006397630.020
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.020
nitrogen compound transportGO:00717052710.020
purine ribonucleotide metabolic processGO:00091502900.019
Human
ribonucleoside catabolic processGO:00424542060.019
Human
leukocyte mediated immunityGO:00024431740.019
carbohydrate derivative catabolic processGO:19011362310.019
Human
regulation of kinase activityGO:00435492490.019
Human
receptor mediated endocytosisGO:0006898510.019
chromatin modificationGO:00165681870.019
ras protein signal transductionGO:0007265770.018
protein targetingGO:00066051430.018
dendrite developmentGO:00163581150.018
centrosome cycleGO:0007098230.018
response to radiationGO:00093141650.018
protein localization to nucleusGO:00345041210.017
nucleoside phosphate metabolic processGO:00067533380.017
Human Yeast
protein alkylationGO:0008213810.017
mitotic cell cycle checkpointGO:0007093310.017
nuclear importGO:0051170950.017
purine nucleoside triphosphate metabolic processGO:00091442260.017
Human
negative regulation of cell proliferationGO:00082852960.017
gonad developmentGO:00084061410.017
regulation of hydrolase activityGO:00513362460.017
double strand break repair via nonhomologous end joiningGO:0006303100.017
Yeast
lymphocyte mediated immunityGO:00024491390.017
purine nucleotide metabolic processGO:00061633020.017
Human
cellular response to organonitrogen compoundGO:00714171450.017
negative regulation of dna replicationGO:000815640.016
Human
purine nucleoside catabolic processGO:00061522050.016
Human
negative regulation of cellular protein metabolic processGO:00322692470.016
protein methylationGO:0006479810.016
spindle organizationGO:0007051280.016
maintenance of locationGO:0051235890.016
Worm
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.016
nucleotide metabolic processGO:00091173320.016
Human Yeast
b cell mediated immunityGO:0019724710.016
positive regulation of nervous system developmentGO:00519622210.016
negative regulation of cell cycle phase transitionGO:1901988480.015
response to inorganic substanceGO:0010035960.015
ribonucleoside triphosphate metabolic processGO:00091992200.015
Human
male meiosisGO:0007140370.015
fertilizationGO:00095661270.015
metaphase plate congressionGO:005131020.015
neuromuscular process controlling balanceGO:0050885590.015
small gtpase mediated signal transductionGO:0007264970.015
dephosphorylationGO:00163111290.015
purine containing compound metabolic processGO:00725213110.015
Human
regulation of protein transportGO:00512231630.015
somatic diversification of immune receptorsGO:0002200530.015
glycosyl compound catabolic processGO:19016582060.014
Human
symbiosis encompassing mutualism through parasitismGO:0044403830.014
peptidyl serine modificationGO:0018209830.014
dna packagingGO:0006323300.014
protein import into nucleusGO:0006606950.014
skeletal system developmentGO:00015013560.014
immunoglobulin mediated immune responseGO:0016064690.014
cellular protein complex assemblyGO:00436231160.014
ribonucleoprotein complex localizationGO:007116610.014
lymphocyte activation involved in immune responseGO:0002285930.014
regulation of cell activationGO:00508652890.014
chromosome separationGO:0051304140.014
response to organic cyclic compoundGO:00140701980.014
g2 dna damage checkpointGO:003157280.014
positive regulation of cell cycleGO:0045787920.013
Worm
negative regulation of cellular amine metabolic processGO:003323910.013
regulation of cytoplasmic transportGO:19036491120.013
neuron migrationGO:00017641220.013
regulation of cell divisionGO:0051302760.013
locomotory behaviorGO:00076261950.013
regulation of protein targetingGO:1903533610.013
cellular response to oxidative stressGO:0034599760.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.013
regulation of establishment of protein localizationGO:00702011810.013
nucleoside catabolic processGO:00091642060.013
Human
skin developmentGO:00435882200.013
reciprocal meiotic recombinationGO:0007131160.013
Yeast
organophosphate biosynthetic processGO:00904071220.013
b cell activation involved in immune responseGO:0002312500.013
positive regulation of apoptotic processGO:00430652170.013
oxidation reduction processGO:00551143420.013
mrna metabolic processGO:0016071840.013
purine nucleoside metabolic processGO:00422782410.013
Human
embryonic organ morphogenesisGO:00485622760.013
ribonucleoside triphosphate catabolic processGO:00092031990.012
Human
muscle tissue developmentGO:00605373080.012
protein maturationGO:00516041760.012
endomembrane system organizationGO:00102561470.012
purine nucleotide catabolic processGO:00061952110.012
Human
nucleoside metabolic processGO:00091162460.012
Human
production of molecular mediator of immune responseGO:00024401030.012
cell fate commitmentGO:00451652100.012
ribonucleotide catabolic processGO:00092612080.012
Human
glycerophospholipid metabolic processGO:0006650710.012
regulation of centriole replicationGO:004659910.012
leukocyte proliferationGO:00706611720.012
sister chromatid segregationGO:0000819200.012
positive regulation of protein transportGO:0051222930.012
carbohydrate metabolic processGO:00059752300.012
response to organonitrogen compoundGO:00102432460.012
nucleoside triphosphate metabolic processGO:00091412300.012
Human
negative regulation of organelle organizationGO:0010639900.012
nuclear exportGO:0051168340.012
purine ribonucleoside metabolic processGO:00461282410.012
Human
purine ribonucleotide catabolic processGO:00091542080.012
Human
mitotic g2 dna damage checkpointGO:000709580.012
negative regulation of phosphate metabolic processGO:00459361840.011
viral processGO:0016032410.011
single organism nuclear importGO:1902593950.011
regulation of protein stabilityGO:0031647520.011
muscle cell differentiationGO:00426922610.011
dna modificationGO:0006304500.011
protein dna complex subunit organizationGO:0071824280.011
protein catabolic processGO:00301632210.011
hematopoietic progenitor cell differentiationGO:00022441430.011
blastocyst growthGO:0001832230.011
regulation of cellular catabolic processGO:00313292420.011
regulation of intracellular protein transportGO:0033157820.011
lipid biosynthetic processGO:00086101790.011
positive regulation of organelle organizationGO:00106381280.011
regulation of intracellular transportGO:00323861590.011
organonitrogen compound biosynthetic processGO:19015661920.011
cellular chemical homeostasisGO:00550822150.011
protein localization to organelleGO:00333651850.011
regulation of nucleocytoplasmic transportGO:0046822730.011
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.011
cellular response to inorganic substanceGO:0071241370.011
negative regulation of phosphorylationGO:00423261660.011
cation transportGO:00068123990.010
response to light stimulusGO:00094161350.010
purine ribonucleoside triphosphate metabolic processGO:00092052200.010
Human
ribonucleoside metabolic processGO:00091192450.010
Human
covalent chromatin modificationGO:00165691630.010
positive regulation of cell developmentGO:00107202370.010
spermatogenesisGO:00072832840.010
rhythmic processGO:00485111740.010
forebrain developmentGO:00309003020.010
regulation of cellular amine metabolic processGO:0033238200.010
response to drugGO:0042493750.010
striated muscle tissue developmentGO:00147062930.010
cellular response to hormone stimulusGO:00328701500.010
regulation of lipid metabolic processGO:00192161180.010

Mre11a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.044
disease of cellular proliferationDOID:1456600.044
hematopoietic system diseaseDOID:7400.030
bone marrow diseaseDOID:496100.030
disease of anatomical entityDOID:700.030
immune system diseaseDOID:291400.030
organ system cancerDOID:005068600.028
immune system cancerDOID:006008300.028
hematologic cancerDOID:253100.028
anemiaDOID:235500.019
aplastic anemiaDOID:1244900.019
leukemiaDOID:124000.016
nervous system diseaseDOID:86300.012