| rna splicing | GO:0008380 | 54 | 0.658 | |
| mrna splicing via spliceosome | GO:0000398 | 43 | 0.636 | |
| regulation of mrna metabolic process | GO:1903311 | 43 | 0.463 | |
| regulation of rna splicing | GO:0043484 | 37 | 0.369 | |
| rna splicing via transesterification reactions | GO:0000375 | 43 | 0.345 | |
| rna splicing via transesterification reactions with bulged adenosine as nucleophile | GO:0000377 | 43 | 0.287 | |
| regulation of mrna processing | GO:0050684 | 41 | 0.253 | |
| mrna metabolic process | GO:0016071 | 84 | 0.234 | |
| mrna processing | GO:0006397 | 63 | 0.217 | |
| rna processing | GO:0006396 | 105 | 0.205 | |
| alternative mrna splicing via spliceosome | GO:0000380 | 12 | 0.201 | |
| regulation of mrna splicing via spliceosome | GO:0048024 | 32 | 0.181 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.150 | |
| regulation of alternative mrna splicing via spliceosome | GO:0000381 | 8 | 0.105 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.087 | |
| nuclear division | GO:0000280 | 158 | 0.086 | |
| amine metabolic process | GO:0009308 | 45 | 0.086 | |
| organelle fission | GO:0048285 | 170 | 0.085 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.080 | |
| endocytosis | GO:0006897 | 168 | 0.079 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.079 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.074 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.074 | |
| chromatin organization | GO:0006325 | 206 | 0.070 | |
| transcription from rna polymerase iii promoter | GO:0006383 | 3 | 0.069 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.066 | |
| receptor mediated endocytosis | GO:0006898 | 51 | 0.060 | |
| hormone metabolic process | GO:0042445 | 86 | 0.060 | |
| regulation of transcription from rna polymerase iii promoter | GO:0006359 | 2 | 0.058 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.056 | |
| chromatin modification | GO:0016568 | 187 | 0.055 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.054 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.053 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.052 | |
| rna interference | GO:0016246 | 2 | 0.050 | |
| cdp choline pathway | GO:0006657 | 2 | 0.049 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.048 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.048 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.047 | |
| glucose metabolic process | GO:0006006 | 92 | 0.046 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.044 | |
| methylation | GO:0032259 | 134 | 0.044 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.043 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.043 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.042 | |
| male meiosis i | GO:0007141 | 16 | 0.041 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.041 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.040 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.039 | |
| gonad development | GO:0008406 | 141 | 0.039 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.038 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.038 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.036 | |
| male gamete generation | GO:0048232 | 285 | 0.036 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.035 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.035 | |
| nuclear transport | GO:0051169 | 139 | 0.035 | |
| gene silencing | GO:0016458 | 38 | 0.035 | |
| digestive tract development | GO:0048565 | 190 | 0.035 | |
| dna metabolic process | GO:0006259 | 303 | 0.035 | |
| epithelial cell development | GO:0002064 | 159 | 0.034 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.034 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.034 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.034 | |
| stem cell fate specification | GO:0048866 | 3 | 0.033 | |
| negative regulation of kinase activity | GO:0033673 | 81 | 0.032 | |
| canonical wnt signaling pathway | GO:0060070 | 130 | 0.032 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.030 | |
| monosaccharide metabolic process | GO:0005996 | 106 | 0.029 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.029 | |
| spermatogenesis | GO:0007283 | 284 | 0.028 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.027 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.027 | |
| peripheral nervous system neuron axonogenesis | GO:0048936 | 3 | 0.027 | |
| negative regulation of cell activation | GO:0050866 | 111 | 0.027 | |
| placenta development | GO:0001890 | 140 | 0.027 | |
| circadian regulation of gene expression | GO:0032922 | 48 | 0.027 | |
| cell maturation | GO:0048469 | 127 | 0.027 | |
| chromosome segregation | GO:0007059 | 48 | 0.027 | |
| negative regulation of transferase activity | GO:0051348 | 85 | 0.026 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 85 | 0.026 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.026 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.026 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.026 | |
| regulation of defense response | GO:0031347 | 233 | 0.025 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.024 | |
| peptidyl threonine modification | GO:0018210 | 31 | 0.024 | |
| cellular response to abiotic stimulus | GO:0071214 | 56 | 0.024 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.024 | |
| cation transport | GO:0006812 | 399 | 0.024 | |
| negative regulation of protein serine threonine kinase activity | GO:0071901 | 49 | 0.024 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.023 | |
| histone lysine demethylation | GO:0070076 | 13 | 0.023 | |
| c4 dicarboxylate transport | GO:0015740 | 3 | 0.023 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.023 | |
| histone lysine methylation | GO:0034968 | 50 | 0.023 | |
| cellular response to organic cyclic compound | GO:0071407 | 87 | 0.021 | |
| regulation of transcription by chromatin organization | GO:0034401 | 0 | 0.021 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.021 | |
| positive regulation of cytokine production | GO:0001819 | 174 | 0.021 | |
| histidine transport | GO:0015817 | 2 | 0.020 | |
| negative regulation of protein processing | GO:0010955 | 79 | 0.020 | |
| pigmentation | GO:0043473 | 71 | 0.020 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.020 | |
| peptidyl tyrosine modification | GO:0018212 | 145 | 0.020 | |
| neural tube development | GO:0021915 | 160 | 0.020 | |
| protein autophosphorylation | GO:0046777 | 61 | 0.020 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.020 | |
| neuroepithelial cell differentiation | GO:0060563 | 37 | 0.020 | |
| protein maturation | GO:0051604 | 176 | 0.020 | |
| nuclear export | GO:0051168 | 34 | 0.019 | |
| synaptic transmission | GO:0007268 | 329 | 0.019 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.019 | |
| mitotic nuclear division | GO:0007067 | 48 | 0.019 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.019 | |
| chromosome organization involved in meiosis | GO:0070192 | 39 | 0.019 | |
| fat cell differentiation | GO:0045444 | 160 | 0.019 | |
| digestive system development | GO:0055123 | 200 | 0.019 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.018 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.018 | |
| hexose metabolic process | GO:0019318 | 98 | 0.018 | |
| response to acid chemical | GO:0001101 | 111 | 0.018 | |
| apical constriction | GO:0003383 | 4 | 0.018 | |
| posttranscriptional gene silencing | GO:0016441 | 10 | 0.018 | |
| mesenchymal cell development | GO:0014031 | 93 | 0.018 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.018 | |
| negative regulation of protein maturation | GO:1903318 | 79 | 0.018 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.018 | |
| regulation of leukocyte apoptotic process | GO:2000106 | 56 | 0.017 | |
| regulation of meiotic cell cycle | GO:0051445 | 34 | 0.017 | |
| neural tube closure | GO:0001843 | 90 | 0.017 | |
| synaptic vesicle localization | GO:0097479 | 59 | 0.017 | |
| carbohydrate biosynthetic process | GO:0016051 | 74 | 0.017 | |
| myotube differentiation | GO:0014902 | 105 | 0.017 | |
| pole plasm assembly | GO:0007315 | 2 | 0.017 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.017 | |
| skeletal muscle cell differentiation | GO:0035914 | 66 | 0.017 | |
| muscle system process | GO:0003012 | 141 | 0.017 | |
| regulation of chromatin organization | GO:1902275 | 57 | 0.016 | |
| oogenesis | GO:0048477 | 56 | 0.016 | |
| gluconeogenesis | GO:0006094 | 39 | 0.016 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.016 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.016 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.016 | |
| wound healing | GO:0042060 | 157 | 0.016 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.016 | |
| translation | GO:0006412 | 93 | 0.016 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.016 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.016 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.016 | |
| histone modification | GO:0016570 | 159 | 0.015 | |
| chromatin silencing at rdna | GO:0000183 | 3 | 0.015 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.015 | |
| immune effector process | GO:0002252 | 321 | 0.015 | |
| peptidyl serine modification | GO:0018209 | 83 | 0.015 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.015 | |
| sequestering of metal ion | GO:0051238 | 19 | 0.015 | |
| regulation of nuclear division | GO:0051783 | 56 | 0.015 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.015 | |
| asymmetric stem cell division | GO:0098722 | 3 | 0.015 | |
| small molecule biosynthetic process | GO:0044283 | 132 | 0.015 | |
| activation of immune response | GO:0002253 | 138 | 0.015 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.015 | |
| multinuclear osteoclast differentiation | GO:0072674 | 4 | 0.015 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.015 | |
| epithelial cell morphogenesis | GO:0003382 | 41 | 0.014 | |
| regulation of carbohydrate metabolic process | GO:0006109 | 75 | 0.014 | |
| stem cell development | GO:0048864 | 219 | 0.014 | |
| stem cell differentiation | GO:0048863 | 268 | 0.014 | |
| central nervous system neuron development | GO:0021954 | 67 | 0.014 | |
| innate immune response | GO:0045087 | 157 | 0.014 | |
| negative regulation of hydrolase activity | GO:0051346 | 71 | 0.014 | |
| embryonic limb morphogenesis | GO:0030326 | 126 | 0.014 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.014 | |
| regulation of cell migration | GO:0030334 | 219 | 0.014 | |
| phosphatidylethanolamine metabolic process | GO:0046337 | 2 | 0.014 | |
| regulation of system process | GO:0044057 | 200 | 0.014 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.014 | |
| methionine transport | GO:0015821 | 1 | 0.014 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.014 | |
| alanine transport | GO:0032328 | 4 | 0.013 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.013 | |
| positive regulation of toll like receptor 4 signaling pathway | GO:0034145 | 1 | 0.013 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.013 | |
| cellular homeostasis | GO:0019725 | 240 | 0.013 | |
| ear development | GO:0043583 | 200 | 0.013 | |
| hexose biosynthetic process | GO:0019319 | 39 | 0.013 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.013 | |
| angiogenesis | GO:0001525 | 201 | 0.013 | |
| negative regulation of ripoptosome assembly involved in necroptotic process | GO:1902443 | 3 | 0.013 | |
| organelle localization | GO:0051640 | 179 | 0.013 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.013 | |
| blood circulation | GO:0008015 | 195 | 0.013 | |
| meiotic cell cycle process | GO:1903046 | 77 | 0.013 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.013 | |
| blastocyst development | GO:0001824 | 80 | 0.013 | |
| regulation of protein localization | GO:0032880 | 231 | 0.013 | |
| negative regulation of gluconeogenesis | GO:0045721 | 9 | 0.013 | |
| peptidyl serine phosphorylation | GO:0018105 | 74 | 0.013 | |
| regulation of t cell proliferation | GO:0042129 | 92 | 0.013 | |
| trabecula morphogenesis | GO:0061383 | 40 | 0.013 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.013 | |
| protein methylation | GO:0006479 | 81 | 0.013 | |
| monosaccharide biosynthetic process | GO:0046364 | 44 | 0.013 | |
| negative regulation of cellular carbohydrate metabolic process | GO:0010677 | 19 | 0.013 | |
| protein processing | GO:0016485 | 163 | 0.013 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.013 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.012 | |
| dna methylation | GO:0006306 | 43 | 0.012 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.012 | |
| gene silencing by rna | GO:0031047 | 19 | 0.012 | |
| cellular response to topologically incorrect protein | GO:0035967 | 25 | 0.012 | |
| sensory perception | GO:0007600 | 245 | 0.012 | |
| skeletal system development | GO:0001501 | 356 | 0.012 | |
| branched chain amino acid transport | GO:0015803 | 2 | 0.012 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.012 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.012 | |
| transmission of nerve impulse | GO:0019226 | 76 | 0.012 | |
| myoblast proliferation | GO:0051450 | 11 | 0.012 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.012 | |
| maintenance of location | GO:0051235 | 89 | 0.012 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.012 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.012 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.012 | |
| pharynx development | GO:0060465 | 1 | 0.012 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.012 | |
| heart morphogenesis | GO:0003007 | 178 | 0.012 | |
| establishment of synaptic vesicle localization | GO:0097480 | 57 | 0.012 | |
| embryonic appendage morphogenesis | GO:0035113 | 126 | 0.012 | |
| oxidation reduction process | GO:0055114 | 342 | 0.012 | |
| circulatory system process | GO:0003013 | 197 | 0.012 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.012 | |
| male meiosis | GO:0007140 | 37 | 0.011 | |
| histone h3 k9 methylation | GO:0051567 | 17 | 0.011 | |
| mesenchyme development | GO:0060485 | 152 | 0.011 | |
| protein deacylation | GO:0035601 | 36 | 0.011 | |
| skeletal system morphogenesis | GO:0048705 | 203 | 0.011 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.011 | |
| sequestering of calcium ion | GO:0051208 | 18 | 0.011 | |
| muscle adaptation | GO:0043500 | 39 | 0.011 | |
| regulation of glucose metabolic process | GO:0010906 | 60 | 0.011 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.011 | |
| developmental pigmentation | GO:0048066 | 40 | 0.011 | |
| l histidine transport | GO:1902024 | 2 | 0.011 | |
| regulation of calcium ion transport | GO:0051924 | 69 | 0.011 | |
| axonogenesis | GO:0007409 | 274 | 0.011 | |
| uterus morphogenesis | GO:0061038 | 2 | 0.011 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.011 | |
| spermatid development | GO:0007286 | 108 | 0.011 | |
| columnar cuboidal epithelial cell differentiation | GO:0002065 | 82 | 0.011 | |
| sister chromatid segregation | GO:0000819 | 20 | 0.011 | |
| 3 utr mediated mrna stabilization | GO:0070935 | 2 | 0.011 | |
| rhythmic process | GO:0048511 | 174 | 0.011 | |
| genitalia development | GO:0048806 | 37 | 0.011 | |
| protein dealkylation | GO:0008214 | 13 | 0.011 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.011 | |
| t cell proliferation | GO:0042098 | 120 | 0.011 | |
| cellular response to lipid | GO:0071396 | 145 | 0.011 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.011 | |
| regulation of myotube differentiation | GO:0010830 | 62 | 0.011 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.011 | |
| cellular carbohydrate metabolic process | GO:0044262 | 119 | 0.010 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.010 | |
| spermatid differentiation | GO:0048515 | 115 | 0.010 | |
| male sex differentiation | GO:0046661 | 109 | 0.010 | |
| embryonic skeletal system morphogenesis | GO:0048704 | 91 | 0.010 | |
| peptidyl threonine phosphorylation | GO:0018107 | 31 | 0.010 | |
| response to retinoic acid | GO:0032526 | 56 | 0.010 | |
| development of primary male sexual characteristics | GO:0046546 | 88 | 0.010 | |
| l histidine transmembrane transport | GO:0089709 | 2 | 0.010 | |
| mapk cascade | GO:0000165 | 281 | 0.010 | |
| histone h3 k9 trimethylation | GO:0036124 | 6 | 0.010 | |
| meiosis i | GO:0007127 | 60 | 0.010 | |
| regulation of adaptive immune response | GO:0002819 | 90 | 0.010 | |
| cell adhesion | GO:0007155 | 329 | 0.010 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.010 | |
| necrotic cell death | GO:0070265 | 30 | 0.010 | |
| regulation of leukocyte mediated immunity | GO:0002703 | 104 | 0.010 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.010 | |
| epithelial tube formation | GO:0072175 | 130 | 0.010 | |
| negative regulation of t cell activation | GO:0050868 | 65 | 0.010 | |
