Mus musculus

0 known processes

H2-M2

histocompatibility 2, M region locus 2

(Aliases: H-2M2,Thy19.4)

H2-M2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immune effector processGO:00022523210.156
Mouse
innate immune responseGO:00450871570.133
regulation of defense responseGO:00313472330.099
regulation of leukocyte mediated immunityGO:00027031040.095
Mouse
cation homeostasisGO:00550802120.080
cytokine productionGO:00018163190.075
Mouse
regulation of leukocyte mediated cytotoxicityGO:0001910380.066
Mouse
positive regulation of defense responseGO:00313491240.065
metal ion homeostasisGO:00550651890.062
positive regulation of reactive oxygen species metabolic processGO:2000379110.061
g protein coupled receptor signaling pathwayGO:00071862430.059
regulation of ion transmembrane transportGO:00347651190.055
response to organonitrogen compoundGO:00102432460.055
positive regulation of protein modification processGO:00314012990.054
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.054
Mouse
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.054
Mouse
reactive oxygen species metabolic processGO:0072593840.053
positive regulation of cell killingGO:0031343330.053
Mouse
positive regulation of leukocyte mediated immunityGO:0002705700.052
Mouse
regulation of inflammatory responseGO:00507271470.048
cellular calcium ion homeostasisGO:00068741190.048
leukocyte mediated immunityGO:00024431740.047
Mouse
cellular response to lipidGO:00713961450.046
regulation of secretionGO:00510462740.045
detection of stimulusGO:0051606840.045
negative regulation of immune system processGO:00026832090.044
calcium ion transportGO:00068161590.044
muscle tissue developmentGO:00605373080.043
transmembrane transportGO:00550854120.043
regulation of cellular amine metabolic processGO:0033238200.043
lymphocyte mediated immunityGO:00024491390.043
Mouse
cellular ion homeostasisGO:00068731650.042
cellular ketone metabolic processGO:0042180840.042
divalent inorganic cation transportGO:00725111780.042
ion transmembrane transportGO:00342203610.042
second messenger mediated signalingGO:0019932730.040
multicellular organismal homeostasisGO:00488711640.040
positive regulation of lymphocyte mediated immunityGO:0002708620.040
Mouse
reactive nitrogen species metabolic processGO:200105700.040
regulation of reactive oxygen species biosynthetic processGO:190342620.039
leukocyte differentiationGO:00025213420.039
blood circulationGO:00080151950.038
activation of immune responseGO:00022531380.038
cellular homeostasisGO:00197252400.038
inorganic cation transmembrane transportGO:00986622070.038
regulation of lymphocyte mediated immunityGO:0002706840.037
Mouse
regulation of mapk cascadeGO:00434082480.037
sequestering of calcium ionGO:0051208180.037
negative regulation of protein modification processGO:00314001630.037
skeletal muscle organ developmentGO:00605381630.037
response to radiationGO:00093141650.037
immune response activating cell surface receptor signaling pathwayGO:0002429720.036
regulation of establishment of protein localizationGO:00702011810.036
cation transportGO:00068123990.035
inflammatory responseGO:00069542440.035
response to organic cyclic compoundGO:00140701980.035
positive regulation of immune effector processGO:00026991070.034
Mouse
regulation of cellular amino acid metabolic processGO:000652150.034
calcium mediated signalingGO:0019722460.034
regulation of reactive oxygen species metabolic processGO:2000377400.034
regulation of kinase activityGO:00435492490.034
nitrogen compound transportGO:00717052710.033
myeloid cell differentiationGO:00300992330.033
regulation of cell killingGO:0031341400.033
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.033
cytosolic calcium ion homeostasisGO:0051480700.032
detection of yeastGO:000187920.032
positive regulation of cellular amine metabolic processGO:003324050.032
response to peptideGO:19016521360.032
blood vessel morphogenesisGO:00485142850.032
lipid transportGO:0006869980.031
bone resorptionGO:0045453380.031
cellular amino acid metabolic processGO:00065201030.031
cellular amine metabolic processGO:0044106440.031
positive regulation of mapk cascadeGO:00434101700.031
cellular metal ion homeostasisGO:00068751510.031
divalent inorganic cation homeostasisGO:00725071380.030
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.030
Mouse
tumor necrosis factor superfamily cytokine productionGO:0071706510.030
regulation of ion transportGO:00432692150.030
sensory perceptionGO:00076002450.030
divalent metal ion transportGO:00708381720.029
regulation of hormone levelsGO:00108172110.029
defense response to other organismGO:00985421970.029
Mouse
adult behaviorGO:00305341350.028
natural killer cell activationGO:0030101440.028
defense response to bacteriumGO:00427421190.028
positive regulation of protein phosphorylationGO:00019342420.028
response to lipopolysaccharideGO:00324961280.028
regulation of response to woundingGO:19030341890.028
membrane organizationGO:00610242450.028
regulation of cytokine productionGO:00018172660.027
Mouse
positive regulation of kinase activityGO:00336741550.027
regulation of metal ion transportGO:00109591060.027
sequestering of metal ionGO:0051238190.027
negative regulation of protein metabolic processGO:00512482820.027
cytoplasmic transportGO:00164822340.027
calcium ion homeostasisGO:00550741270.027
regulation of membrane potentialGO:00423911920.027
regulation of transmembrane transportGO:00347621280.026
lymphocyte differentiationGO:00300982420.026
mapk cascadeGO:00001652810.026
regulation of blood pressureGO:0008217930.026
fat soluble vitamin biosynthetic processGO:004236240.026
regulation of neuron deathGO:19012141340.025
organic hydroxy compound metabolic processGO:19016152030.025
tumor necrosis factor productionGO:0032640500.025
synaptic transmissionGO:00072683290.025
positive regulation of cell developmentGO:00107202370.025
production of molecular mediator of immune responseGO:00024401030.025
response to light stimulusGO:00094161350.025
protein kinase b signalingGO:0043491740.024
regulation of protein kinase b signalingGO:0051896560.024
leukocyte activation involved in immune responseGO:00023661260.024
positive regulation of innate immune responseGO:0045089800.024
multicellular organismal signalingGO:0035637910.024
immune response regulating cell surface receptor signaling pathwayGO:0002768800.024
compound eye developmentGO:004874910.023
protein catabolic processGO:00301632210.023
response to drugGO:0042493750.023
regulation of cellular ketone metabolic processGO:0010565660.023
reactive oxygen species biosynthetic processGO:190340980.023
nucleobase containing small molecule metabolic processGO:00550863520.023
regulation of t cell mediated immunityGO:0002709340.023
Mouse
positive regulation of erk1 and erk2 cascadeGO:0070374470.023
response to molecule of bacterial originGO:00022371430.023
regulation of t cell activationGO:00508631700.023
glial cell differentiationGO:00100011310.023
positive regulation of nervous system developmentGO:00519622210.023
cellular response to acid chemicalGO:0071229680.023
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.023
regulation of erk1 and erk2 cascadeGO:0070372710.022
regulation of protein localizationGO:00328802310.022
cellular response to cytokine stimulusGO:00713451890.022
amine metabolic processGO:0009308450.022
extrinsic apoptotic signaling pathwayGO:00971911260.022
positive regulation of programmed cell deathGO:00430682180.022
positive regulation of homeostatic processGO:0032846640.022
response to testosteroneGO:003357430.022
cellular chemical homeostasisGO:00550822150.022
positive regulation of ion transportGO:0043270650.021
meiotic cell cycle processGO:1903046770.021
gland developmentGO:00487323300.021
regulation of striated muscle cell differentiationGO:0051153810.021
defense response to virusGO:0051607680.021
Mouse
adaptive immune responseGO:00022501550.021
Mouse
microtubule based processGO:00070172360.021
regulation of natural killer cell mediated immunityGO:0002715190.021
negative regulation of intracellular signal transductionGO:19025321670.021
fat cell differentiationGO:00454441600.021
negative regulation of phosphorus metabolic processGO:00105631840.021
regulation of protein serine threonine kinase activityGO:00719001570.021
locomotory behaviorGO:00076261950.021
cation transmembrane transportGO:00986552660.021
circulatory system processGO:00030131970.021
immunoglobulin productionGO:0002377730.021
mature dendritic cell differentiationGO:009702930.020
macromolecule catabolic processGO:00090572810.020
positive regulation of transferase activityGO:00513471670.020
regulation of cell activationGO:00508652890.020
positive regulation of reactive oxygen species biosynthetic processGO:190342820.020
positive regulation of protein kinase b signalingGO:0051897320.020
positive regulation of chemotaxisGO:0050921380.020
myeloid leukocyte differentiationGO:00025731190.020
regulation of protein transportGO:00512231630.020
regulation of ossificationGO:00302781120.020
dephosphorylationGO:00163111290.020
regulation of tumor necrosis factor productionGO:0032680490.019
positive regulation of secretion by cellGO:19035321140.019
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.019
regulation of anatomical structure sizeGO:00900661780.019
positive regulation of cellular amino acid metabolic processGO:004576430.019
regulation of ion transmembrane transporter activityGO:0032412540.019
positive regulation of natural killer cell mediated immunityGO:0002717160.019
negative regulation of macrophage apoptotic processGO:200011030.019
positive regulation of inflammatory responseGO:0050729470.019
positive regulation of tumor necrosis factor productionGO:0032760300.019
inorganic ion transmembrane transportGO:00986602340.019
positive regulation of cell deathGO:00109422240.019
regulation of systemic arterial blood pressureGO:0003073610.019
maintenance of locationGO:0051235890.019
peptide transportGO:00158331330.019
immune response activating signal transductionGO:00027571160.019
regulation of protein kinase activityGO:00458592320.019
mitotic cell cycleGO:00002781950.019
stimulatory c type lectin receptor signaling pathwayGO:000222320.018
male gamete generationGO:00482322850.018
cellular divalent inorganic cation homeostasisGO:00725031270.018
amide transportGO:00428861380.018
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.018
anatomical structure homeostasisGO:00602491450.018
protein processingGO:00164851630.018
organonitrogen compound biosynthetic processGO:19015661920.018
oxidation reduction processGO:00551143420.018
cellular response to lipopolysaccharideGO:0071222770.018
protein localization to nucleusGO:00345041210.018
cell type specific apoptotic processGO:00972852680.018
cytokine mediated signaling pathwayGO:00192211150.018
posttranscriptional regulation of gene expressionGO:00106081550.018
rhythmic processGO:00485111740.018
antigen processing and presentationGO:0019882470.018
Mouse
cyclic nucleotide metabolic processGO:0009187590.018
regulation of secretion by cellGO:19035302490.018
ossificationGO:00015032160.018
positive regulation of cell activationGO:00508671580.018
potassium ion transportGO:0006813520.018
cell cell recognitionGO:0009988440.018
natural killer cell inhibitory signaling pathwayGO:000276920.018
pole plasm assemblyGO:000731520.017
sodium ion transportGO:0006814730.017
myeloid leukocyte migrationGO:0097529570.017
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.017
t cell activationGO:00421102890.017
positive regulation of adaptive immune responseGO:0002821610.017
Mouse
leukocyte chemotaxisGO:0030595690.017
signal transduction in absence of ligandGO:0038034550.017
fertilizationGO:00095661270.017
carbohydrate derivative biosynthetic processGO:19011371830.017
erk1 and erk2 cascadeGO:0070371770.017
muscle cell differentiationGO:00426922610.017
regulation of monocyte chemotaxisGO:009002530.017
negative regulation of t cell activationGO:0050868650.016
leukocyte migrationGO:00509001240.016
regulation of transferase activityGO:00513382630.016
regulation of natural killer cell mediated cytotoxicityGO:0042269190.016
cellular response to organonitrogen compoundGO:00714171450.016
detection of abiotic stimulusGO:0009582600.016
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.016
Mouse
negative regulation of homeostatic processGO:0032845710.016
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
cell killingGO:0001906670.016
Mouse
hormone secretionGO:00468791280.016
cd4 positive alpha beta t cell cytokine productionGO:003574340.016
cellular alcohol biosynthetic processGO:004410830.016
response to alcoholGO:0097305480.016
axon ensheathmentGO:0008366760.016
response to oxygen levelsGO:0070482620.016
regulation of body fluid levelsGO:00508781620.016
immune response regulating signaling pathwayGO:00027641250.016
positive regulation of behaviorGO:0048520400.016
cellular response to growth factor stimulusGO:00713631970.016
chemotaxisGO:00069352470.016
dna metabolic processGO:00062593030.016
bone remodelingGO:0046849530.015
myotube differentiationGO:00149021050.015
positive regulation of bone remodelingGO:0046852130.015
action potentialGO:0001508780.015
regulation of system processGO:00440572000.015
response to steroid hormoneGO:0048545560.015
neuron migrationGO:00017641220.015
eosinophil activationGO:004330710.015
myeloid leukocyte activationGO:0002274830.015
positive regulation of t cell activationGO:00508701010.015
negative regulation of serotonin secretionGO:001406320.015
gliogenesisGO:00420631410.015
positive regulation of t cell mediated cytotoxicityGO:0001916150.015
Mouse
positive regulation of response to woundingGO:1903036660.015
lipid localizationGO:00108761260.015
organelle fissionGO:00482851700.015
positive regulation of cell motilityGO:20001471160.015
regulation of multi organism processGO:00439001110.015
regulation of peptide transportGO:0090087910.015
hexose metabolic processGO:0019318980.015
negative regulation of apoptotic signaling pathwayGO:20012341040.015
homeostasis of number of cellsGO:00488722100.015
regulation of lymphocyte activationGO:00512492400.015
negative regulation of phosphate metabolic processGO:00459361840.015
negative regulation of protein phosphorylationGO:00019331260.014
regulation of calcium ion transportGO:0051924690.014
regulation of vasculature developmentGO:1901342880.014
tissue homeostasisGO:00018941150.014
negative regulation of cell proliferationGO:00082852960.014
developmental growth involved in morphogenesisGO:00605601380.014
cellular response to molecule of bacterial originGO:0071219830.014
striated muscle tissue developmentGO:00147062930.014
regulation of g protein coupled receptor protein signaling pathwayGO:0008277370.014
t cell differentiationGO:00302171740.014
defense response to gram positive bacteriumGO:0050830500.014
intracellular protein transportGO:00068862040.014
positive regulation of cytokine productionGO:00018191740.014
Mouse
calcium ion transmembrane transportGO:0070588850.014
protein localization to organelleGO:00333651850.014
circadian rhythmGO:00076231140.014
natural killer cell mediated immunityGO:0002228290.014
positive regulation of dendritic cell chemotaxisGO:200051010.014
endocytosisGO:00068971680.014
cell chemotaxisGO:0060326810.014
carbohydrate metabolic processGO:00059752300.014
negative regulation of cell migrationGO:0030336590.014
ribonucleotide metabolic processGO:00092592910.014
keratinocyte migrationGO:005154630.014
transmission of nerve impulseGO:0019226760.014
response to insulinGO:00328681000.014
regulation of intracellular transportGO:00323861590.013
secondary alcohol metabolic processGO:190265230.013
regulation of neuron differentiationGO:00456642810.013
meiotic nuclear divisionGO:00071261150.013
epithelial cell proliferationGO:00506731740.013
regulation of map kinase activityGO:00434051200.013
lateral inhibitionGO:004633110.013
interleukin 12 productionGO:0032615320.013
small gtpase mediated signal transductionGO:0007264970.013
regulation of interleukin 12 productionGO:0032655300.013
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193200.013
cognitionGO:00508901490.013
establishment of protein localization to organelleGO:00725941180.013
negative regulation of phosphorylationGO:00423261660.013
regulation of homeostatic processGO:00328441820.013
regulation of transporter activityGO:0032409570.013
intrinsic apoptotic signaling pathwayGO:00971931320.013
immunoglobulin mediated immune responseGO:0016064690.013
vascular process in circulatory systemGO:0003018620.013
organ regenerationGO:003110020.013
female sex differentiationGO:0046660840.013
coenzyme metabolic processGO:0006732520.013
helper t cell chemotaxisGO:003570410.013
cell recognitionGO:0008037830.013
cytokine biosynthetic processGO:0042089680.013
cytokine metabolic processGO:0042107710.013
apoptotic signaling pathwayGO:00971903060.013
ras protein signal transductionGO:0007265770.013
ameboidal type cell migrationGO:00016671280.013
positive regulation of apoptotic processGO:00430652170.013
regulation of bone remodelingGO:0046850280.013
angiogenesisGO:00015252010.012
organic hydroxy compound transportGO:0015850930.012
nucleoside phosphate metabolic processGO:00067533380.012
negative regulation of cell sizeGO:004579230.012
hormone metabolic processGO:0042445860.012
cell maturationGO:00484691270.012
antigen processing and presentation of endogenous peptide antigen via mhc class ibGO:000247640.012
Mouse
lung developmentGO:00303241640.012
t cell mediated immunityGO:0002456500.012
Mouse
tissue remodelingGO:00487711020.012
peptide hormone secretionGO:00300721090.012
glucose homeostasisGO:00425931280.012
protein targetingGO:00066051430.012
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200260.012
digestionGO:0007586400.012
striated muscle cell developmentGO:00550021250.012
cellular lipid metabolic processGO:00442553230.012
meiosis iGO:0007127600.012
organelle localizationGO:00516401790.012
establishment of organelle localizationGO:00516561220.012
neutrophil chemotaxisGO:0030593360.012
regulation of cell motilityGO:20001452360.012
regulation of proteolysisGO:00301621640.012
positive regulation of proteolysisGO:0045862850.012
fatty acid metabolic processGO:00066311210.012
regulation of cell cycle processGO:00105641600.012
meiotic cell cycleGO:00513211220.012
intracellular mrna localizationGO:000829840.012
cytosolic calcium ion transportGO:0060401480.012
histone modificationGO:00165701590.012
negative regulation of defense responseGO:0031348770.012
response to oxidative stressGO:00069791230.012
regulation of organelle organizationGO:00330432890.012
camera type eye developmentGO:00430102660.012
regulation of protein secretionGO:0050708820.012
regulation of endocytosisGO:0030100690.012
protein modification by small protein conjugation or removalGO:00706472070.012
carboxylic acid biosynthetic processGO:0046394860.012
regulation of cytokine biosynthetic processGO:0042035590.012
positive regulation of natural killer cell mediated cytotoxicityGO:0045954160.012
protein secretionGO:00093061110.012
natural killer cell mediated cytotoxicityGO:0042267290.012
cellularizationGO:000734910.012
nuclear divisionGO:00002801580.011
regulation of epithelial cell proliferationGO:00506781410.011
organophosphate biosynthetic processGO:00904071220.011
response to growth factorGO:00708481980.011
male meiosis iGO:0007141160.011
positive regulation of angiogenesisGO:0045766460.011
developmental maturationGO:00217001930.011
response to decreased oxygen levelsGO:0036293590.011
positive regulation of secretionGO:00510471300.011
regulation of hormone secretionGO:0046883880.011
memoryGO:0007613580.011
nucleoside phosphate biosynthetic processGO:1901293790.011
macromolecule glycosylationGO:0043413550.011
skeletal system developmentGO:00015013560.011
regulation of adaptive immune responseGO:0002819900.011
Mouse
purine containing compound metabolic processGO:00725213110.011
negative regulation of cell activationGO:00508661110.011
cellular response to dna damage stimulusGO:00069742070.011
epithelial tube morphogenesisGO:00605623030.011
energy derivation by oxidation of organic compoundsGO:0015980770.011
positive regulation of cell migrationGO:00303351090.011
unsaturated fatty acid metabolic processGO:0033559310.011
alcohol metabolic processGO:00060661160.011
morphogenesis of a branching epitheliumGO:00611381930.011
nucleotide metabolic processGO:00091173320.011
regulation of acute inflammatory responseGO:0002673270.011
negative regulation of molecular functionGO:00440922580.011
neuron deathGO:00709971540.011
positive regulation of hormone secretionGO:0046887380.011
response to molecule of fungal originGO:000223840.011
regulation of tissue remodelingGO:0034103380.011
oocyte axis specificationGO:000730920.011
positive regulation of cytokine biosynthetic processGO:0042108400.011
small molecule biosynthetic processGO:00442831320.011
leukocyte mediated cytotoxicityGO:0001909620.011
Mouse
regulation of t cell differentiationGO:0045580830.011
neuron projection guidanceGO:00974851410.011
regulation of acute inflammatory response to non antigenic stimulusGO:000287720.011
nucleocytoplasmic transportGO:00069131390.011
regulation of apoptotic signaling pathwayGO:20012331970.011
regulation of angiogenesisGO:0045765810.011
interspecies interaction between organismsGO:0044419830.011
protein maturationGO:00516041760.011
nitric oxide biosynthetic processGO:0006809250.011
retina development in camera type eyeGO:00600411190.011
cytokine production involved in immune responseGO:0002367340.011
chromatin modificationGO:00165681870.011
purine ribonucleotide biosynthetic processGO:0009152590.011
innate immune response activating cell surface receptor signaling pathwayGO:000222040.011
positive regulation of cytosolic calcium ion concentrationGO:0007204650.011
cd8 positive alpha beta t cell extravasationGO:003569730.011
protein ubiquitinationGO:00165671710.011
purine nucleotide metabolic processGO:00061633020.011
purine containing compound biosynthetic processGO:0072522700.011
satellite cell activation involved in skeletal muscle regenerationGO:001490130.011
regulation of peptide secretionGO:0002791770.011
cellular alcohol metabolic processGO:004410730.011
cartilage developmentGO:00512161400.010
regulation of production of molecular mediator of immune responseGO:0002700650.010
microtubule cytoskeleton organizationGO:00002261570.010
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.010
regulation of alpha beta t cell activationGO:0046634530.010
cellular macromolecule catabolic processGO:00442652060.010
regulation of leukocyte differentiationGO:19021051590.010
cellular response to abiotic stimulusGO:0071214560.010
regulation of action potentialGO:009890040.010
monocarboxylic acid metabolic processGO:00327871910.010
stem cell developmentGO:00488642190.010
glycoprotein metabolic processGO:00091001160.010
cellular response to biotic stimulusGO:0071216920.010
cell surface pattern recognition receptor signaling pathwayGO:000275220.010
odontogenesisGO:0042476780.010
regulation of cytokine secretionGO:0050707610.010
osteoclast differentiationGO:0030316620.010
response to inorganic substanceGO:0010035960.010
nuclear importGO:0051170950.010
calcium ion transport into cytosolGO:0060402480.010
carbohydrate homeostasisGO:00335001280.010

H2-M2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.029
nervous system diseaseDOID:86300.025
sensory system diseaseDOID:005015500.025
disease of anatomical entityDOID:700.025
eye diseaseDOID:561400.025
eye and adnexa diseaseDOID:149200.025
retinal diseaseDOID:567900.025
musculoskeletal system diseaseDOID:1700.023
connective tissue diseaseDOID:6500.023
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
central nervous system diseaseDOID:33100.017
organ system cancerDOID:005068600.014
inherited metabolic disorderDOID:65500.014
immune system diseaseDOID:291400.013
retinal degenerationDOID:846600.013
neurodegenerative diseaseDOID:128900.012
disease of mental healthDOID:15000.011
bone diseaseDOID:008000100.011