Mus musculus

0 known processes

Psmc2

proteasome (prosome, macropain) 26S subunit, ATPase 2

Psmc2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
proteasomal protein catabolic processGO:0010498980.954
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.926
ubiquitin dependent protein catabolic processGO:00065111290.877
Human Yeast
modification dependent macromolecule catabolic processGO:00436321330.872
Human Yeast
protein catabolic processGO:00301632210.864
Human Yeast
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.860
Yeast
modification dependent protein catabolic processGO:00199411330.840
Human Yeast
proteolysis involved in cellular protein catabolic processGO:00516031470.838
Human Yeast
spindle assembly involved in mitosisGO:009030740.838
proteasome assemblyGO:004324810.825
Yeast
microtubule cytoskeleton organization involved in mitosisGO:190285040.772
cellular macromolecule catabolic processGO:00442652060.726
Human Yeast
macromolecule catabolic processGO:00090572810.696
Human Yeast
cellular protein catabolic processGO:00442571550.682
Human Yeast
mitotic cell cycleGO:00002781950.613
mitotic cell cycle processGO:19030471590.591
cellular response to dna damage stimulusGO:00069742070.580
Fly
dna templated transcriptional preinitiation complex assemblyGO:007089740.574
Yeast
dna metabolic processGO:00062593030.523
sperm egg recognitionGO:0035036370.404
proteasomal ubiquitin independent protein catabolic processGO:001049910.380
fertilizationGO:00095661270.373
gonad developmentGO:00084061410.270
mitotic nuclear divisionGO:0007067480.233
protein modification by small protein removalGO:0070646210.194
positive regulation of hydrolase activityGO:00513451480.193
organelle fissionGO:00482851700.191
nuclear divisionGO:00002801580.175
protein modification by small protein conjugation or removalGO:00706472070.164
cellular protein complex assemblyGO:00436231160.148
Yeast
protein modification by small protein conjugationGO:00324461870.148
negative regulation of protein metabolic processGO:00512482820.147
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.141
camera type eye developmentGO:00430102660.140
ribonucleoside monophosphate catabolic processGO:0009158570.139
Human
positive regulation of dna templated transcription elongationGO:003278620.128
dna templated transcription initiationGO:0006352130.127
Yeast
regulation of protein maturationGO:1903317960.120
regulation of proteolysisGO:00301621640.120
regulation of cellular catabolic processGO:00313292420.117
binding of sperm to zona pellucidaGO:0007339340.113
spindle organizationGO:0007051280.113
purine ribonucleotide metabolic processGO:00091502900.109
Human
regulation of hydrolase activityGO:00513362460.108
single fertilizationGO:0007338820.108
organelle assemblyGO:00709251770.101
dna repairGO:00062811070.101
protein refoldingGO:004202610.099
protein importGO:00170381010.097
regulation of peptidase activityGO:0052547960.096
regulation of cell cycle processGO:00105641600.095
regulation of endopeptidase activityGO:0052548890.095
ribonucleoside triphosphate catabolic processGO:00092031990.095
Human
positive regulation of proteolysisGO:0045862850.094
purine nucleoside catabolic processGO:00061522050.090
Human
negative regulation of cellular protein metabolic processGO:00322692470.090
posttranscriptional regulation of gene expressionGO:00106081550.086
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.085
Yeast
maternal determination of anterior posterior axis embryoGO:000835820.084
protein deubiquitinationGO:0016579190.081
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435150.081
protein ubiquitinationGO:00165671710.080
purine nucleotide catabolic processGO:00061952110.080
Human
negative regulation of protein maturationGO:1903318790.079
purine ribonucleoside triphosphate metabolic processGO:00092052200.077
Human
positive regulation of transcription initiation from rna polymerase ii promoterGO:006026150.077
Yeast
protein import into nucleusGO:0006606950.076
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.075
pore complex assemblyGO:004693130.074
negative regulation of cell proliferationGO:00082852960.073
spermatogenesisGO:00072832840.073
purine ribonucleoside metabolic processGO:00461282410.073
Human
organophosphate catabolic processGO:00464342320.073
Human
protein localization to nucleusGO:00345041210.071
regulation of mitotic cell cycle phase transitionGO:1901990730.067
chromatin organizationGO:00063252060.067
cellular nitrogen compound catabolic processGO:00442702800.066
Human
regulation of protein processingGO:0070613960.062
oocyte constructionGO:000730820.061
spermatid differentiationGO:00485151150.060
nucleotide catabolic processGO:00091662170.060
Human
protein processingGO:00164851630.059
nuclear importGO:0051170950.059
cell divisionGO:00513011200.056
transcription elongation from rna polymerase ii promoterGO:000636890.056
development of primary sexual characteristicsGO:00451371430.055
regulation of proteasomal protein catabolic processGO:0061136460.054
positive regulation of endopeptidase activityGO:0010950430.053
negative regulation of protein catabolic processGO:0042177360.053
protein acylationGO:0043543640.051
regulation of protein modification by small protein conjugation or removalGO:1903320570.051
regulation of cellular protein catabolic processGO:1903362610.051
regulation of protein catabolic processGO:00421761080.051
Yeast
negative regulation of proteolysisGO:0045861740.050
intracellular protein transportGO:00068862040.048
oocyte anterior posterior axis specificationGO:000731420.048
regulation of protein targetingGO:1903533610.048
rna interferenceGO:001624620.048
toxin transportGO:1901998380.048
male gamete generationGO:00482322850.048
cell cell recognitionGO:0009988440.046
protein stabilizationGO:0050821250.046
negative regulation of cellular protein catabolic processGO:1903363220.045
nuclear transportGO:00511691390.045
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.045
histone acetylationGO:0016573410.044
double strand break repairGO:0006302480.044
genitalia developmentGO:0048806370.044
heterocycle catabolic processGO:00467002800.043
Human
regulation of inclusion body assemblyGO:009008310.043
regulation of protein stabilityGO:0031647520.041
protein polymerizationGO:0051258570.041
negative regulation of cell developmentGO:00107211690.041
positive regulation of peptidase activityGO:0010952490.041
chromatin modificationGO:00165681870.040
protein maturationGO:00516041760.039
nucleoside triphosphate catabolic processGO:00091432050.039
Human
purine nucleoside monophosphate catabolic processGO:0009128580.038
Human
nucleobase containing small molecule metabolic processGO:00550863520.038
Human
transcription initiation from rna polymerase ii promoterGO:000636780.038
Yeast
microtubule cytoskeleton organizationGO:00002261570.038
regulation of cell cycleGO:00517262810.038
mitotic cytokinesisGO:000028140.038
spindle assemblyGO:0051225130.038
protein targetingGO:00066051430.037
regulation of mitotic cell cycleGO:00073461260.037
glycosyl compound metabolic processGO:19016572460.036
Human
mitotic spindle organizationGO:0007052100.036
regulation of ion transmembrane transportGO:00347651190.036
dna recombinationGO:0006310920.035
embryonic organ morphogenesisGO:00485622760.035
mapk cascadeGO:00001652810.035
synaptic transmissionGO:00072683290.034
establishment of protein localization to organelleGO:00725941180.034
regulation of transmembrane transportGO:00347621280.034
nucleoside monophosphate catabolic processGO:0009125590.034
Human
protein localization to organelleGO:00333651850.034
negative regulation of molecular functionGO:00440922580.034
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.034
atp catabolic processGO:0006200550.033
Human
protein dna complex subunit organizationGO:0071824280.033
Yeast
molting cycleGO:0042303900.033
purine containing compound catabolic processGO:00725232130.032
Human
ribonucleoside triphosphate metabolic processGO:00091992200.032
Human
positive regulation of cell deathGO:00109422240.031
organic cyclic compound catabolic processGO:19013612950.031
Human
purine nucleoside triphosphate catabolic processGO:00091462030.030
Human
oocyte axis specificationGO:000730920.030
transmembrane transportGO:00550854120.029
regulation of ion transportGO:00432692150.029
regulation of receptor activityGO:0010469410.029
regulation of intracellular transportGO:00323861590.028
microtubule based processGO:00070172360.028
chromosome segregationGO:0007059480.028
positive regulation of apoptotic processGO:00430652170.028
oocyte differentiationGO:0009994350.027
purine containing compound metabolic processGO:00725213110.026
Human
ribonucleotide catabolic processGO:00092612080.026
Human
regulation of cellular component biogenesisGO:00440871810.026
Yeast
nucleoside catabolic processGO:00091642060.026
Human
multicellular organismal agingGO:0010259240.026
Worm
positive regulation of cellular component biogenesisGO:0044089940.026
Yeast
response to organonitrogen compoundGO:00102432460.025
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.025
sensory organ morphogenesisGO:00905962420.025
organic acid biosynthetic processGO:0016053860.025
purine nucleotide metabolic processGO:00061633020.025
Human
regulation of transcription initiation from rna polymerase ii promoterGO:006026060.025
Yeast
positive regulation of protein modification processGO:00314012990.025
positive regulation of protein catabolic processGO:0045732600.024
Yeast
peptidyl amino acid modificationGO:00181933360.024
positive regulation of cellular amino acid metabolic processGO:004576430.024
regulation of chromosome organizationGO:0033044830.024
regulation of establishment of protein localizationGO:00702011810.024
sperm individualizationGO:000729110.024
determination of adult lifespanGO:0008340110.023
Worm
negative regulation of cellular catabolic processGO:0031330470.023
cell recognitionGO:0008037830.023
internal protein amino acid acetylationGO:0006475420.023
ribonucleoside monophosphate metabolic processGO:0009161800.023
Human
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.023
regulation of cell cycle phase transitionGO:1901987770.022
posttranscriptional gene silencingGO:0016441100.022
internal peptidyl lysine acetylationGO:0018393420.022
single organism nuclear importGO:1902593950.022
regulation of stem cell differentiationGO:2000736500.022
regulation of cysteine type endopeptidase activityGO:2000116650.022
blastocyst developmentGO:0001824800.022
cell maturationGO:00484691270.022
ribonucleoside metabolic processGO:00091192450.021
Human
regulation of anion transportGO:0044070270.021
photoreceptor cell developmentGO:0042461400.021
nucleoside phosphate metabolic processGO:00067533380.021
Human
carboxylic acid biosynthetic processGO:0046394860.020
positive regulation of protein phosphorylationGO:00019342420.020
negative regulation of protein processingGO:0010955790.020
inorganic cation transmembrane transportGO:00986622070.020
regulation of organ morphogenesisGO:20000271440.020
regulation of kinase activityGO:00435492490.020
single organism cell adhesionGO:00986021560.019
positive regulation of transferase activityGO:00513471670.019
negative regulation of cell cycle phase transitionGO:1901988480.019
ribonucleotide metabolic processGO:00092592910.019
Human
regulation of protein complex assemblyGO:0043254830.019
Yeast
nucleotide metabolic processGO:00091173320.019
Human
protein methylationGO:0006479810.019
positive regulation of cellular catabolic processGO:00313311480.019
single organismal cell cell adhesionGO:00163371310.019
regulation of protein ubiquitinationGO:0031396520.019
aromatic compound catabolic processGO:00194392860.019
Human
purine ribonucleoside catabolic processGO:00461302050.019
Human
positive regulation of cellular protein catabolic processGO:1903364340.018
stem cell differentiationGO:00488632680.018
protein foldingGO:0006457280.018
cation transmembrane transportGO:00986552660.018
positive regulation of programmed cell deathGO:00430682180.018
purine ribonucleoside monophosphate catabolic processGO:0009169570.018
Human
dna integrity checkpointGO:0031570280.017
negative regulation of mitotic cell cycle phase transitionGO:1901991450.017
peptidyl lysine modificationGO:0018205770.017
nucleoside triphosphate metabolic processGO:00091412300.017
Human
nucleoside phosphate catabolic processGO:19012922220.017
Human
ion transmembrane transportGO:00342203610.017
regulation of mitosisGO:0007088290.017
spermatid developmentGO:00072861080.017
regulation of phosphatidylcholine biosynthetic processGO:200124520.017
embryonic axis specificationGO:0000578300.017
regulation of cell divisionGO:0051302760.017
regulation of transferase activityGO:00513382630.017
regulation of protein kinase activityGO:00458592320.017
positive regulation of mapk cascadeGO:00434101700.016
leukocyte migrationGO:00509001240.016
stress activated mapk cascadeGO:0051403800.016
purine ribonucleotide catabolic processGO:00091542080.016
Human
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.016
palate developmentGO:0060021760.016
purine ribonucleoside triphosphate catabolic processGO:00092071990.015
Human
carbohydrate derivative catabolic processGO:19011362310.015
Human
leukocyte proliferationGO:00706611720.015
locomotory behaviorGO:00076261950.015
regulation of cellular amino acid metabolic processGO:000652150.015
regulation of nuclear divisionGO:0051783560.015
developmental programmed cell deathGO:0010623410.015
methylationGO:00322591340.015
axonogenesisGO:00074092740.015
negative regulation of phosphorylationGO:00423261660.015
negative regulation of mitotic cell cycleGO:0045930580.015
regulation of protein transportGO:00512231630.015
anion transportGO:00068201770.015
macromolecule methylationGO:00434141200.015
cytoplasmic transportGO:00164822340.014
negative regulation of endopeptidase activityGO:0010951440.014
regulation of sequence specific dna binding transcription factor activityGO:00510901060.014
germ cell developmentGO:00072811850.014
neural tube formationGO:00018411080.014
t cell proliferationGO:00420981200.014
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.014
Yeast
peptidyl lysine acetylationGO:0018394450.014
negative regulation of cell cycleGO:00457861230.014
oogenesisGO:0048477560.014
regulation of protein localization to nucleusGO:1900180600.014
negative regulation of phosphorus metabolic processGO:00105631840.013
recombinational repairGO:0000725210.013
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051220.013
purine nucleoside monophosphate metabolic processGO:0009126810.013
Human
lateral inhibitionGO:004633110.013
nucleotide excision repairGO:0006289130.013
positive regulation of protein complex assemblyGO:0031334450.013
Yeast
regulation of nucleocytoplasmic transportGO:0046822730.013
respiratory system developmentGO:00605411900.013
regulation of cell growthGO:0001558910.013
hematopoietic progenitor cell differentiationGO:00022441430.013
extracellular structure organizationGO:00430621480.013
reactive oxygen species biosynthetic processGO:190340980.013
regulation of intracellular protein transportGO:0033157820.013
oocyte developmentGO:0048599330.013
regulation of cytoplasmic transportGO:19036491120.013
chromosome separationGO:0051304140.013
gene silencingGO:0016458380.012
negative regulation of cellular component organizationGO:00511291940.012
regulation of transporter activityGO:0032409570.012
cell cycle checkpointGO:0000075470.012
glycosyl compound catabolic processGO:19016582060.012
Human
calcium ion transportGO:00068161590.012
regulation of body fluid levelsGO:00508781620.012
regulation of inflammatory responseGO:00507271470.012
dna damage checkpointGO:0000077260.012
purine nucleoside triphosphate metabolic processGO:00091442260.012
Human
negative regulation of intracellular signal transductionGO:19025321670.012
positive regulation of cellular amine metabolic processGO:003324050.012
protein alkylationGO:0008213810.012
rna splicingGO:0008380540.012
positive regulation of protein localization to nucleusGO:1900182300.012
organonitrogen compound catabolic processGO:19015652640.012
Human
regulation of dna templated transcription initiationGO:200014270.012
Yeast
cytokinesisGO:0000910170.012
monocarboxylic acid biosynthetic processGO:0072330610.011
dephosphorylationGO:00163111290.011
double strand break repair via homologous recombinationGO:0000724210.011
t cell activationGO:00421102890.011
cytoplasmic microtubule organizationGO:0031122140.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
regulation of membrane potentialGO:00423911920.011
regulation of epithelial cell proliferationGO:00506781410.011
cell fate commitmentGO:00451652100.011
cellular response to organonitrogen compoundGO:00714171450.011
forebrain developmentGO:00309003020.011
regulation of cellular ketone metabolic processGO:0010565660.011
cellular amine metabolic processGO:0044106440.011
regulation of protein bindingGO:0043393600.011
gene silencing by rnaGO:0031047190.011
er associated ubiquitin dependent protein catabolic processGO:0030433100.011
negative regulation of retinal cell programmed cell deathGO:004667120.011
dna templated transcription elongationGO:0006354130.011
negative regulation of cell cycle processGO:0010948690.011
epithelial cell proliferationGO:00506731740.011
positive regulation of dna templated transcription initiationGO:200014450.011
Yeast
regulation of organelle organizationGO:00330432890.011
embryonic eye morphogenesisGO:0048048290.010
cellular response to hormone stimulusGO:00328701500.010
inorganic ion transmembrane transportGO:00986602340.010
epithelial tube morphogenesisGO:00605623030.010
female gamete generationGO:0007292740.010
regionalizationGO:00030023370.010
response to peptide hormoneGO:00434341270.010
negative regulation of protein phosphorylationGO:00019331260.010
negative regulation of alcohol biosynthetic processGO:190293140.010

Psmc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.045
neuromuscular diseaseDOID:44000.045
disease of anatomical entityDOID:700.045
neuropathyDOID:87000.045