Mus musculus

135 known processes

Mcph1

microcephaly, primary autosomal recessive 1

(Aliases: MCT,D030046N04Rik,BRIT1,MGC66518,5430437K10Rik)

Mcph1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.199
cellular response to dna damage stimulusGO:00069742070.188
dna repairGO:00062811070.117
male gamete generationGO:00482322850.117
amine metabolic processGO:0009308450.101
dna recombinationGO:0006310920.097
cellular amino acid metabolic processGO:00065201030.087
spermatogenesisGO:00072832840.084
cellular amine metabolic processGO:0044106440.082
regulation of cellular amine metabolic processGO:0033238200.081
cellular ketone metabolic processGO:0042180840.069
meiotic cell cycle processGO:1903046770.067
organelle fissionGO:00482851700.066
positive regulation of cellular amino acid metabolic processGO:004576430.064
microtubule based processGO:00070172360.061
peptidyl amino acid modificationGO:00181933360.060
positive regulation of cellular amine metabolic processGO:003324050.059
regulation of cellular ketone metabolic processGO:0010565660.057
regulation of cellular amino acid metabolic processGO:000652150.056
nuclear divisionGO:00002801580.054
double strand break repairGO:0006302480.054
protein modification by small protein conjugation or removalGO:00706472070.051
meiotic nuclear divisionGO:00071261150.049
apoptotic signaling pathwayGO:00971903060.048
protein processingGO:00164851630.046
organic cyclic compound catabolic processGO:19013612950.044
macromolecule catabolic processGO:00090572810.042
positive regulation of protein modification processGO:00314012990.042
mitotic cell cycleGO:00002781950.042
chromatin organizationGO:00063252060.041
regulation of organelle organizationGO:00330432890.040
negative regulation of cellular protein metabolic processGO:00322692470.039
response to organonitrogen compoundGO:00102432460.039
meiotic cell cycleGO:00513211220.038
immune effector processGO:00022523210.037
protein modification by small protein conjugationGO:00324461870.037
microtubule cytoskeleton organizationGO:00002261570.037
positive regulation of programmed cell deathGO:00430682180.037
positive regulation of cell deathGO:00109422240.036
histone modificationGO:00165701590.036
regulation of transferase activityGO:00513382630.036
protein maturationGO:00516041760.035
cellular macromolecule catabolic processGO:00442652060.034
cellular response to organonitrogen compoundGO:00714171450.034
intracellular protein transportGO:00068862040.033
reactive oxygen species metabolic processGO:0072593840.033
nitrogen compound transportGO:00717052710.032
regulation of apoptotic signaling pathwayGO:20012331970.032
positive regulation of protein phosphorylationGO:00019342420.031
chromatin modificationGO:00165681870.031
negative regulation of cell proliferationGO:00082852960.031
leukocyte differentiationGO:00025213420.031
protein ubiquitinationGO:00165671710.031
mitotic cell cycle processGO:19030471590.031
regulation of cell activationGO:00508652890.030
cytoplasmic transportGO:00164822340.030
small gtpase mediated signal transductionGO:0007264970.030
nucleobase containing small molecule metabolic processGO:00550863520.029
cellular nitrogen compound catabolic processGO:00442702800.029
cilium morphogenesisGO:00602711020.029
ribonucleotide metabolic processGO:00092592910.029
transmembrane transportGO:00550854120.028
regulation of lymphocyte activationGO:00512492400.028
skeletal system developmentGO:00015013560.028
regulation of cellular catabolic processGO:00313292420.028
purine containing compound metabolic processGO:00725213110.028
positive regulation of apoptotic processGO:00430652170.028
negative regulation of protein metabolic processGO:00512482820.028
cation transportGO:00068123990.027
germ cell developmentGO:00072811850.027
nuclear transportGO:00511691390.027
leukocyte mediated immunityGO:00024431740.027
regulation of establishment of protein localizationGO:00702011810.027
covalent chromatin modificationGO:00165691630.027
ras protein signal transductionGO:0007265770.026
heterocycle catabolic processGO:00467002800.026
meiosis iGO:0007127600.026
regulation of protein localizationGO:00328802310.026
cellular homeostasisGO:00197252400.026
membrane organizationGO:00610242450.026
lateral inhibitionGO:004633110.025
lymphocyte differentiationGO:00300982420.025
posttranscriptional regulation of gene expressionGO:00106081550.025
methylationGO:00322591340.025
cell type specific apoptotic processGO:00972852680.025
anatomical structure homeostasisGO:00602491450.025
gland developmentGO:00487323300.025
muscle tissue developmentGO:00605373080.024
ribose phosphate metabolic processGO:00196932910.024
striated muscle tissue developmentGO:00147062930.024
negative regulation of cellular component organizationGO:00511291940.024
cellular protein catabolic processGO:00442571550.023
regulation of proteolysisGO:00301621640.023
regulation of kinase activityGO:00435492490.023
t cell activationGO:00421102890.023
negative regulation of cellular amino acid metabolic processGO:004576300.023
nucleoside phosphate metabolic processGO:00067533380.023
organonitrogen compound biosynthetic processGO:19015661920.023
regulation of cellular response to stressGO:00801351590.023
cytokine productionGO:00018163190.022
response to acid chemicalGO:00011011110.022
nucleotide metabolic processGO:00091173320.022
regulation of secretion by cellGO:19035302490.022
purine ribonucleotide metabolic processGO:00091502900.022
cellular response to cytokine stimulusGO:00713451890.022
ion transmembrane transportGO:00342203610.022
negative regulation of cell cycle processGO:0010948690.022
b cell activationGO:00421131610.021
purine containing compound catabolic processGO:00725232130.021
response to radiationGO:00093141650.021
protein targetingGO:00066051430.021
protein methylationGO:0006479810.021
regulation of anatomical structure sizeGO:00900661780.021
multicellular organismal homeostasisGO:00488711640.021
regulation of protein transportGO:00512231630.021
macromolecule methylationGO:00434141200.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.020
mapk cascadeGO:00001652810.020
regulation of membrane potentialGO:00423911920.020
aromatic compound catabolic processGO:00194392860.020
carbohydrate derivative catabolic processGO:19011362310.020
homeostasis of number of cellsGO:00488722100.020
muscle cell differentiationGO:00426922610.020
establishment of protein localization to organelleGO:00725941180.020
leukocyte activation involved in immune responseGO:00023661260.020
intrinsic apoptotic signaling pathwayGO:00971931320.020
myeloid cell differentiationGO:00300992330.019
regulation of protein processingGO:0070613960.019
organophosphate catabolic processGO:00464342320.019
regulation of cell cycleGO:00517262810.019
stem cell differentiationGO:00488632680.019
purine nucleoside triphosphate catabolic processGO:00091462030.019
histone methylationGO:0016571710.019
positive regulation of organelle organizationGO:00106381280.019
nucleoside phosphate catabolic processGO:19012922220.019
regulation of cell projection organizationGO:00313442060.019
regulation of secretionGO:00510462740.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.019
lymphocyte mediated immunityGO:00024491390.019
inorganic ion transmembrane transportGO:00986602340.018
negative regulation of cellular amine metabolic processGO:003323910.018
negative regulation of phosphorylationGO:00423261660.018
purine ribonucleoside metabolic processGO:00461282410.018
metal ion homeostasisGO:00550651890.018
divalent metal ion transportGO:00708381720.018
regulation of protein kinase activityGO:00458592320.018
maintenance of locationGO:0051235890.018
protein importGO:00170381010.018
male meiosisGO:0007140370.018
regulation of defense responseGO:00313472330.018
regulation of cytokine productionGO:00018172660.018
respiratory system developmentGO:00605411900.018
divalent inorganic cation transportGO:00725111780.018
regulation of protein catabolic processGO:00421761080.018
cellular protein complex assemblyGO:00436231160.018
double strand break repair via homologous recombinationGO:0000724210.018
regulation of cell cycle processGO:00105641600.018
nucleoside triphosphate metabolic processGO:00091412300.018
nucleocytoplasmic transportGO:00069131390.018
ubiquitin dependent protein catabolic processGO:00065111290.018
cell activation involved in immune responseGO:00022631260.018
negative regulation of phosphorus metabolic processGO:00105631840.018
blood vessel morphogenesisGO:00485142850.018
proteolysis involved in cellular protein catabolic processGO:00516031470.018
spermatid developmentGO:00072861080.018
carbohydrate metabolic processGO:00059752300.018
cellular chemical homeostasisGO:00550822150.018
cellular lipid metabolic processGO:00442553230.018
telomere maintenanceGO:0000723190.017
regulation of hydrolase activityGO:00513362460.017
purine nucleoside triphosphate metabolic processGO:00091442260.017
sensory organ morphogenesisGO:00905962420.017
response to oxidative stressGO:00069791230.017
epithelial cell proliferationGO:00506731740.017
purine ribonucleoside triphosphate metabolic processGO:00092052200.017
protein secretionGO:00093061110.017
chemotaxisGO:00069352470.017
neuron apoptotic processGO:00514021420.017
somatic cell dna recombinationGO:0016444510.017
carbohydrate derivative biosynthetic processGO:19011371830.017
oxidation reduction processGO:00551143420.017
purine ribonucleoside triphosphate catabolic processGO:00092071990.017
regulation of chromosome organizationGO:0033044830.017
multicellular organism growthGO:00352641610.017
glycosyl compound metabolic processGO:19016572460.017
response to inorganic substanceGO:0010035960.017
sensory perceptionGO:00076002450.016
adaptive immune responseGO:00022501550.016
regulation of intracellular transportGO:00323861590.016
regulation of cellular protein catabolic processGO:1903362610.016
placenta developmentGO:00018901400.016
response to peptideGO:19016521360.016
spermatid differentiationGO:00485151150.016
regulation of cellular component biogenesisGO:00440871810.016
negative regulation of immune system processGO:00026832090.016
regulation of neuron differentiationGO:00456642810.016
protein localization to nucleusGO:00345041210.016
negative regulation of molecular functionGO:00440922580.016
action potentialGO:0001508780.016
cation homeostasisGO:00550802120.016
histone lysine methylationGO:0034968500.016
negative regulation of intracellular signal transductionGO:19025321670.016
organonitrogen compound catabolic processGO:19015652640.016
sister chromatid segregationGO:0000819200.016
regulation of reactive oxygen species metabolic processGO:2000377400.016
regulation of inflammatory responseGO:00507271470.016
regulation of ion transportGO:00432692150.016
regulation of leukocyte differentiationGO:19021051590.016
translationGO:0006412930.016
purine ribonucleoside catabolic processGO:00461302050.016
peptidyl tyrosine modificationGO:00182121450.015
divalent inorganic cation homeostasisGO:00725071380.015
purine nucleotide catabolic processGO:00061952110.015
regulation of leukocyte mediated immunityGO:00027031040.015
negative regulation of protein maturationGO:1903318790.015
positive regulation of cell activationGO:00508671580.015
response to molecule of bacterial originGO:00022371430.015
multicellular organismal signalingGO:0035637910.015
purine ribonucleotide catabolic processGO:00091542080.015
cellular response to growth factor stimulusGO:00713631970.015
single organism nuclear importGO:1902593950.015
ribonucleotide catabolic processGO:00092612080.015
production of molecular mediator of immune responseGO:00024401030.015
regulation of homeostatic processGO:00328441820.015
engulfment of apoptotic cellGO:004365230.015
positive regulation of transferase activityGO:00513471670.015
modification dependent protein catabolic processGO:00199411330.015
negative regulation of apoptotic signaling pathwayGO:20012341040.015
chromosome segregationGO:0007059480.015
nucleoside metabolic processGO:00091162460.015
cellular response to lipidGO:00713961450.015
positive regulation of lymphocyte activationGO:00512511400.015
peptide transportGO:00158331330.015
g protein coupled receptor signaling pathwayGO:00071862430.015
protein localization to organelleGO:00333651850.015
circulatory system processGO:00030131970.015
cell fate commitmentGO:00451652100.015
purine nucleoside catabolic processGO:00061522050.015
female gamete generationGO:0007292740.015
synaptic transmissionGO:00072683290.015
ossificationGO:00015032160.015
purine nucleoside metabolic processGO:00422782410.014
protein alkylationGO:0008213810.014
negative regulation of organelle organizationGO:0010639900.014
peptidyl lysine modificationGO:0018205770.014
regulation of adaptive immune responseGO:0002819900.014
regulation of mitotic cell cycleGO:00073461260.014
leukocyte proliferationGO:00706611720.014
protein catabolic processGO:00301632210.014
glycosyl compound catabolic processGO:19016582060.014
negative regulation of phosphate metabolic processGO:00459361840.014
negative regulation of cell cycleGO:00457861230.014
regulation of protein maturationGO:1903317960.014
regulation of cell motilityGO:20001452360.014
peptide hormone secretionGO:00300721090.014
negative regulation of cellular catabolic processGO:0031330470.014
calcium ion transportGO:00068161590.014
sequestering of calcium ionGO:0051208180.014
inorganic cation transmembrane transportGO:00986622070.014
nucleoside catabolic processGO:00091642060.014
transmission of nerve impulseGO:0019226760.014
regulation of t cell activationGO:00508631700.014
organelle localizationGO:00516401790.014
lymphocyte activation involved in immune responseGO:0002285930.014
wnt signaling pathwayGO:00160551880.014
ribonucleoside metabolic processGO:00091192450.014
regulation of hormone levelsGO:00108172110.014
cilium assemblyGO:0042384810.014
cation transmembrane transportGO:00986552660.014
t cell differentiationGO:00302171740.014
ribonucleoside catabolic processGO:00424542060.014
mitochondrion organizationGO:00070051340.014
nucleoside triphosphate catabolic processGO:00091432050.014
fat cell differentiationGO:00454441600.014
amide transportGO:00428861380.013
regulation of cytoskeleton organizationGO:00514931220.013
organic anion transportGO:00157111370.013
tissue homeostasisGO:00018941150.013
connective tissue developmentGO:00614481790.013
regulation of cell migrationGO:00303342190.013
dephosphorylationGO:00163111290.013
extrinsic apoptotic signaling pathwayGO:00971911260.013
nuclear importGO:0051170950.013
heart morphogenesisGO:00030071780.013
nucleotide catabolic processGO:00091662170.013
synapsisGO:0007129340.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.013
innate immune responseGO:00450871570.013
response to organic cyclic compoundGO:00140701980.013
rhythmic processGO:00485111740.013
regulation of mapk cascadeGO:00434082480.013
regionalizationGO:00030023370.013
positive regulation of apoptotic signaling pathwayGO:2001235950.013
regulation of multi organism processGO:00439001110.013
morphogenesis of embryonic epitheliumGO:00163311590.013
response to extracellular stimulusGO:00099911270.013
inflammatory responseGO:00069542440.013
purine nucleotide metabolic processGO:00061633020.013
cellular metal ion homeostasisGO:00068751510.013
response to lipopolysaccharideGO:00324961280.013
peptidyl tyrosine phosphorylationGO:00181081430.013
lymphocyte proliferationGO:00466511640.013
negative regulation of proteolysisGO:0045861740.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
regulation of lymphocyte mediated immunityGO:0002706840.013
ribonucleoside triphosphate catabolic processGO:00092031990.013
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.013
anion transportGO:00068201770.013
angiogenesisGO:00015252010.013
cell adhesionGO:00071553290.013
immunoglobulin productionGO:0002377730.013
lipid biosynthetic processGO:00086101790.013
response to peptide hormoneGO:00434341270.013
regulation of mitotic cell cycle phase transitionGO:1901990730.013
negative regulation of protein modification processGO:00314001630.013
epithelial tube morphogenesisGO:00605623030.013
response to growth factorGO:00708481980.013
protein import into nucleusGO:0006606950.013
proteasomal protein catabolic processGO:0010498980.013
cellular response to hormone stimulusGO:00328701500.013
negative regulation of protein processingGO:0010955790.013
fertilizationGO:00095661270.013
cellular ion homeostasisGO:00068731650.013
glucose homeostasisGO:00425931280.013
regulation of system processGO:00440572000.012
cytokine mediated signaling pathwayGO:00192211150.012
dna replicationGO:0006260520.012
carbohydrate homeostasisGO:00335001280.012
regulation of neuron projection developmentGO:00109751690.012
developmental maturationGO:00217001930.012
regulation of neuron deathGO:19012141340.012
activation of immune responseGO:00022531380.012
positive regulation of cellular catabolic processGO:00313311480.012
locomotory behaviorGO:00076261950.012
positive regulation of immune effector processGO:00026991070.012
b cell differentiationGO:0030183780.012
positive regulation of secretionGO:00510471300.012
negative regulation of neuron apoptotic processGO:0043524920.012
embryonic placenta developmentGO:0001892980.012
leukocyte migrationGO:00509001240.012
regulation of response to woundingGO:19030341890.012
cellular component assembly involved in morphogenesisGO:00109271390.012
organic hydroxy compound metabolic processGO:19016152030.012
peptidyl serine phosphorylationGO:0018105740.012
regulation of lymphocyte differentiationGO:00456191070.012
myeloid leukocyte differentiationGO:00025731190.012
organophosphate biosynthetic processGO:00904071220.012
cellular response to oxidative stressGO:0034599760.012
regulation of translationGO:0006417710.012
dna endoreduplicationGO:004202340.012
modification dependent macromolecule catabolic processGO:00436321330.012
hexose metabolic processGO:0019318980.012
hematopoietic progenitor cell differentiationGO:00022441430.012
protein polymerizationGO:0051258570.012
response to light stimulusGO:00094161350.012
response to reactive oxygen speciesGO:0000302560.011
endocytosisGO:00068971680.011
dna dependent dna replicationGO:0006261240.011
cellular response to peptide hormone stimulusGO:0071375920.011
regulation of cytoplasmic transportGO:19036491120.011
organelle assemblyGO:00709251770.011
neuron deathGO:00709971540.011
axonogenesisGO:00074092740.011
somatic diversification of immune receptorsGO:0002200530.011
cognitionGO:00508901490.011
blastocyst developmentGO:0001824800.011
positive regulation of hydrolase activityGO:00513451480.011
protein autophosphorylationGO:0046777610.011
single organism cell adhesionGO:00986021560.011
negative regulation of dna replicationGO:000815640.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
regulation of proteasomal protein catabolic processGO:0061136460.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.011
compound eye developmentGO:004874910.011
chromosome separationGO:0051304140.011
stem cell developmentGO:00488642190.011
positive regulation of nervous system developmentGO:00519622210.011
digestive system developmentGO:00551232000.011
cellular response to acid chemicalGO:0071229680.011
nucleic acid phosphodiester bond hydrolysisGO:0090305490.011
sequestering of metal ionGO:0051238190.011
gene silencingGO:0016458380.011
calcium ion homeostasisGO:00550741270.011
hormone secretionGO:00468791280.011
positive regulation of cell developmentGO:00107202370.011
protein kinase b signalingGO:0043491740.011
skeletal muscle organ developmentGO:00605381630.011
positive regulation of kinase activityGO:00336741550.011
endomembrane system organizationGO:00102561470.011
regulation of transmembrane transportGO:00347621280.011
learning or memoryGO:00076111480.011
regulation of protein serine threonine kinase activityGO:00719001570.011
regulation of leukocyte proliferationGO:00706631210.011
rho protein signal transductionGO:0007266320.011
respiratory tube developmentGO:00303231670.011
cellular response to external stimulusGO:0071496880.011
mitotic sister chromatid segregationGO:0000070140.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
glycerolipid metabolic processGO:00464861220.011
tube formationGO:00351481400.011
cellular calcium ion homeostasisGO:00068741190.010
response to nutrient levelsGO:00316671090.010
regulation of production of molecular mediator of immune responseGO:0002700650.010
dendrite developmentGO:00163581150.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.010
positive regulation of cytokine productionGO:00018191740.010
regulation of cell sizeGO:0008361720.010
mitotic recombinationGO:000631230.010
camera type eye developmentGO:00430102660.010
lung developmentGO:00303241640.010
chromosome organization involved in meiosisGO:0070192390.010
reactive nitrogen species metabolic processGO:200105700.010
telencephalon developmentGO:00215371860.010
protein localization to membraneGO:00726571080.010
sulfur compound metabolic processGO:00067901000.010
neural tube developmentGO:00219151600.010
forebrain developmentGO:00309003020.010
blood circulationGO:00080151950.010
male sex differentiationGO:00466611090.010
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.010
positive regulation of cellular component biogenesisGO:0044089940.010
positive regulation of defense responseGO:00313491240.010
regulation of intracellular protein transportGO:0033157820.010
carboxylic acid transportGO:00469421000.010
urogenital system developmentGO:00016552610.010
t cell proliferationGO:00420981200.010
response to insulinGO:00328681000.010

Mcph1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
immune system diseaseDOID:291400.034
cancerDOID:16200.032
organ system cancerDOID:005068600.032
disease of cellular proliferationDOID:1456600.032
hematopoietic system diseaseDOID:7400.029
nervous system diseaseDOID:86300.024
central nervous system diseaseDOID:33100.022
congenital hypoplastic anemiaDOID:134200.018
aplastic anemiaDOID:1244900.018
bone marrow diseaseDOID:496100.018
anemiaDOID:235500.018
neurodegenerative diseaseDOID:128900.013
musculoskeletal system diseaseDOID:1700.011
disease of metabolismDOID:001466700.011
cardiovascular system diseaseDOID:128700.010