IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Stt3b

STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)

(Aliases: 1300006C19Rik,Simp)

Entrez: 68292
Ensembl: ENSMUSG00000032437
UniProtKB: Q3TDQ1

Process Predictions
Disease Predictions

Stt3b biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
protein glycosylation	GO:0006486	55	0.227	Human
macromolecule glycosylation	GO:0043413	55	0.164	Human
glycoprotein biosynthetic process	GO:0009101	89	0.101	Human
cellular macromolecule catabolic process	GO:0044265	206	0.087	Human
spermatogenesis	GO:0007283	284	0.086
ubiquitin dependent protein catabolic process	GO:0006511	129	0.076	Human
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.075	Human
lateral inhibition	GO:0046331	1	0.072
male gamete generation	GO:0048232	285	0.072
cation transmembrane transport	GO:0098655	266	0.068
glycoprotein metabolic process	GO:0009100	116	0.065	Human
transmembrane transport	GO:0055085	412	0.062
modification dependent macromolecule catabolic process	GO:0043632	133	0.062	Human
cellular protein catabolic process	GO:0044257	155	0.058	Human
cation transport	GO:0006812	399	0.057
spermatid development	GO:0007286	108	0.057
carbohydrate metabolic process	GO:0005975	230	0.056	Human
negative regulation of cellular protein metabolic process	GO:0032269	247	0.056
ion transmembrane transport	GO:0034220	361	0.054
intrinsic apoptotic signaling pathway	GO:0097193	132	0.051
proteasomal protein catabolic process	GO:0010498	98	0.048	Human
small gtpase mediated signal transduction	GO:0007264	97	0.046
inorganic ion transmembrane transport	GO:0098660	234	0.045
glycosylation	GO:0070085	62	0.044	Human
cellular amino acid metabolic process	GO:0006520	103	0.044
protein catabolic process	GO:0030163	221	0.042	Human
carbohydrate derivative biosynthetic process	GO:1901137	183	0.042	Human
spermatid differentiation	GO:0048515	115	0.041
macromolecule catabolic process	GO:0009057	281	0.040	Human
divalent metal ion transport	GO:0070838	172	0.036
cation homeostasis	GO:0055080	212	0.036
inorganic cation transmembrane transport	GO:0098662	207	0.035
metal ion homeostasis	GO:0055065	189	0.034
protein n linked glycosylation	GO:0006487	12	0.033	Human
regulation of organelle organization	GO:0033043	289	0.033
mrna metabolic process	GO:0016071	84	0.033
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.032	Human
apoptotic signaling pathway	GO:0097190	306	0.031
translation	GO:0006412	93	0.031
epidermis development	GO:0008544	187	0.030
amine metabolic process	GO:0009308	45	0.029
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.029
purine nucleotide metabolic process	GO:0006163	302	0.029
cellular amine metabolic process	GO:0044106	44	0.029
divalent inorganic cation transport	GO:0072511	178	0.028
regulation of cellular catabolic process	GO:0031329	242	0.028
regulation of translation	GO:0006417	71	0.028
organic hydroxy compound metabolic process	GO:1901615	203	0.028
skin development	GO:0043588	220	0.027
germ cell development	GO:0007281	185	0.027
oocyte axis specification	GO:0007309	2	0.026
dna repair	GO:0006281	107	0.026
negative regulation of protein metabolic process	GO:0051248	282	0.025
fertilization	GO:0009566	127	0.025
protein modification by small protein conjugation or removal	GO:0070647	207	0.025
mitotic cell cycle	GO:0000278	195	0.025
metencephalon development	GO:0022037	89	0.025
cell division	GO:0051301	120	0.025
ribonucleotide metabolic process	GO:0009259	291	0.024
cellular ion homeostasis	GO:0006873	165	0.024
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.024
posttranscriptional regulation of gene expression	GO:0010608	155	0.023
purine containing compound metabolic process	GO:0072521	311	0.023
nucleoside phosphate catabolic process	GO:1901292	222	0.023
ras protein signal transduction	GO:0007265	77	0.022
homeostasis of number of cells	GO:0048872	210	0.022
purine ribonucleotide metabolic process	GO:0009150	290	0.022
cellular response to cytokine stimulus	GO:0071345	189	0.022
cellular chemical homeostasis	GO:0055082	215	0.022
divalent inorganic cation homeostasis	GO:0072507	138	0.022
modification dependent protein catabolic process	GO:0019941	133	0.022	Human
meiotic cell cycle	GO:0051321	122	0.021
oocyte construction	GO:0007308	2	0.021
organelle fission	GO:0048285	170	0.021
cellular lipid metabolic process	GO:0044255	323	0.021
intrinsic apoptotic signaling pathway in response to dna damage	GO:0008630	57	0.021
nitrogen compound transport	GO:0071705	271	0.021
maintenance of location	GO:0051235	89	0.021
cell adhesion	GO:0007155	329	0.020
cellular response to lipid	GO:0071396	145	0.020
cellular metal ion homeostasis	GO:0006875	151	0.020
transition metal ion transport	GO:0000041	38	0.020
nucleobase containing small molecule metabolic process	GO:0055086	352	0.020
regulation of cellular amine metabolic process	GO:0033238	20	0.020
developmental maturation	GO:0021700	193	0.020
mitotic cell cycle process	GO:1903047	159	0.020
compound eye development	GO:0048749	1	0.019
negative regulation of cell cycle	GO:0045786	123	0.019
cellular response to dna damage stimulus	GO:0006974	207	0.019
cellular homeostasis	GO:0019725	240	0.019
endocytosis	GO:0006897	168	0.019
chemotaxis	GO:0006935	247	0.019
ribose phosphate metabolic process	GO:0019693	291	0.019
nucleotide metabolic process	GO:0009117	332	0.019
purine nucleotide catabolic process	GO:0006195	211	0.019
nucleotide catabolic process	GO:0009166	217	0.018
myeloid cell homeostasis	GO:0002262	114	0.018
response to radiation	GO:0009314	165	0.018
positive regulation of cellular catabolic process	GO:0031331	148	0.018
locomotory behavior	GO:0007626	195	0.018
protein ubiquitination	GO:0016567	171	0.018
response to nutrient levels	GO:0031667	109	0.018
lipoprotein metabolic process	GO:0042157	43	0.018
multicellular organism growth	GO:0035264	161	0.018
negative regulation of protein modification process	GO:0031400	163	0.018
cerebellar cortex development	GO:0021695	48	0.018
sequestering of metal ion	GO:0051238	19	0.018
cellular nitrogen compound catabolic process	GO:0044270	280	0.018
endomembrane system organization	GO:0010256	147	0.018
transmission of nerve impulse	GO:0019226	76	0.018
negative regulation of cellular amine metabolic process	GO:0033239	1	0.018
dephosphorylation	GO:0016311	129	0.018
purine nucleoside catabolic process	GO:0006152	205	0.018
cytoplasmic transport	GO:0016482	234	0.017
cellular ketone metabolic process	GO:0042180	84	0.017
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.017
response to oxidative stress	GO:0006979	123	0.017
male genitalia morphogenesis	GO:0048808	4	0.017
regulation of mitotic cell cycle	GO:0007346	126	0.017
purine nucleoside metabolic process	GO:0042278	241	0.017
lipid biosynthetic process	GO:0008610	179	0.017
ribonucleoside catabolic process	GO:0042454	206	0.017
lung development	GO:0030324	164	0.017
regulation of intrinsic apoptotic signaling pathway	GO:2001242	61	0.017
regulation of multi organism process	GO:0043900	111	0.016
ribonucleoside metabolic process	GO:0009119	245	0.016
anatomical structure homeostasis	GO:0060249	145	0.016
nuclear division	GO:0000280	158	0.016
regulation of cellular ketone metabolic process	GO:0010565	66	0.016
positive regulation of hydrolase activity	GO:0051345	148	0.016
regulation of nucleoside metabolic process	GO:0009118	130	0.016
nucleoside metabolic process	GO:0009116	246	0.016
gland development	GO:0048732	330	0.016
cellular response to hormone stimulus	GO:0032870	150	0.016
purine ribonucleoside metabolic process	GO:0046128	241	0.016
aromatic compound catabolic process	GO:0019439	286	0.015
regulation of purine nucleotide catabolic process	GO:0033121	122	0.015
regulation of cell cycle	GO:0051726	281	0.015
regulation of cytoplasmic transport	GO:1903649	112	0.015
organonitrogen compound catabolic process	GO:1901565	264	0.015
regulation of protein catabolic process	GO:0042176	108	0.015
respiratory tube development	GO:0030323	167	0.015
regulation of apoptotic signaling pathway	GO:2001233	197	0.015
calcium ion homeostasis	GO:0055074	127	0.015
multicellular organismal homeostasis	GO:0048871	164	0.015
protein modification by small protein conjugation	GO:0032446	187	0.015
regulation of protein localization	GO:0032880	231	0.014
response to topologically incorrect protein	GO:0035966	25	0.014	Human
regulation of homeostatic process	GO:0032844	182	0.014
adult behavior	GO:0030534	135	0.014
hindbrain development	GO:0030902	128	0.014
regulation of hydrolase activity	GO:0051336	246	0.014
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.014
cell substrate adhesion	GO:0031589	130	0.014
organophosphate catabolic process	GO:0046434	232	0.014
response to unfolded protein	GO:0006986	21	0.014	Human
respiratory system development	GO:0060541	190	0.014
extracellular structure organization	GO:0043062	148	0.014
protein polymerization	GO:0051258	57	0.014
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.014
negative regulation of growth	GO:0045926	99	0.014
cellular response to biotic stimulus	GO:0071216	92	0.014
cellularization	GO:0007349	1	0.014
actin polymerization or depolymerization	GO:0008154	54	0.014
axonogenesis	GO:0007409	274	0.014
microtubule based process	GO:0007017	236	0.014
cerebellum development	GO:0021549	77	0.014
protein maturation	GO:0051604	176	0.014
protein localization to organelle	GO:0033365	185	0.014
regulation of cellular amino acid metabolic process	GO:0006521	5	0.014
regulation of protein complex assembly	GO:0043254	83	0.014
regionalization	GO:0003002	337	0.013
kidney development	GO:0001822	213	0.013
organophosphate biosynthetic process	GO:0090407	122	0.013
regulation of cellular component biogenesis	GO:0044087	181	0.013
cell growth	GO:0016049	130	0.013
regulation of purine nucleotide metabolic process	GO:1900542	169	0.013
immune effector process	GO:0002252	321	0.013
negative regulation of nervous system development	GO:0051961	156	0.013
renal system development	GO:0072001	225	0.013
anion transport	GO:0006820	177	0.013
urogenital system development	GO:0001655	261	0.013
purine ribonucleotide catabolic process	GO:0009154	208	0.013
circulatory system process	GO:0003013	197	0.013
placenta development	GO:0001890	140	0.013
regulation of nucleotide metabolic process	GO:0006140	169	0.013
cellular response to organonitrogen compound	GO:0071417	145	0.013
cellular response to growth factor stimulus	GO:0071363	197	0.013
nucleoside phosphate metabolic process	GO:0006753	338	0.012
actin filament organization	GO:0007015	113	0.012
carbohydrate derivative catabolic process	GO:1901136	231	0.012	Human
intracellular mrna localization	GO:0008298	4	0.012
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.012
multi multicellular organism process	GO:0044706	109	0.012
male anatomical structure morphogenesis	GO:0090598	4	0.012
regulation of establishment of protein localization	GO:0070201	181	0.012
negative regulation of intracellular signal transduction	GO:1902532	167	0.012
regulation of hormone levels	GO:0010817	211	0.012
forebrain development	GO:0030900	302	0.012
intracellular protein transport	GO:0006886	204	0.012
oocyte anterior posterior axis specification	GO:0007314	2	0.012
lipid transport	GO:0006869	98	0.012
positive regulation of programmed cell death	GO:0043068	218	0.012
ossification	GO:0001503	216	0.012
cell fate commitment	GO:0045165	210	0.012
heterocycle catabolic process	GO:0046700	280	0.012
negative regulation of transferase activity	GO:0051348	85	0.012
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.012
response to organonitrogen compound	GO:0010243	246	0.012
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.012
negative regulation of synapse assembly	GO:0051964	3	0.012
response to acid chemical	GO:0001101	111	0.012
ribonucleotide catabolic process	GO:0009261	208	0.012
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.012
male sex differentiation	GO:0046661	109	0.012
adult locomotory behavior	GO:0008344	91	0.012
response to growth factor	GO:0070848	198	0.011
regulation of actin filament based process	GO:0032970	99	0.011
innate immune response	GO:0045087	157	0.011
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	56	0.011
peptidyl amino acid modification	GO:0018193	336	0.011	Human
purine containing compound catabolic process	GO:0072523	213	0.011
calcium ion transport	GO:0006816	159	0.011
tissue homeostasis	GO:0001894	115	0.011
regulation of anatomical structure size	GO:0090066	178	0.011
regulation of ion transport	GO:0043269	215	0.011
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.011
carbohydrate homeostasis	GO:0033500	128	0.011
mitotic nuclear division	GO:0007067	48	0.011
actin cytoskeleton organization	GO:0030036	220	0.011
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.011
cellular protein complex assembly	GO:0043623	116	0.011
regulation of membrane potential	GO:0042391	192	0.011
negative regulation of cellular component organization	GO:0051129	194	0.011
nucleoside triphosphate metabolic process	GO:0009141	230	0.011
meiotic nuclear division	GO:0007126	115	0.011
cellular response to organic cyclic compound	GO:0071407	87	0.011
positive regulation of protein transport	GO:0051222	93	0.011
regulation of cell activation	GO:0050865	289	0.011
formation of organ boundary	GO:0010160	1	0.011
phospholipid metabolic process	GO:0006644	87	0.011
oxidation reduction process	GO:0055114	342	0.011
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.011
regulation of protein stability	GO:0031647	52	0.011
negative regulation of translation	GO:0017148	22	0.011
epithelial cell proliferation	GO:0050673	174	0.011
sequestering of calcium ion	GO:0051208	18	0.011
cellular amide metabolic process	GO:0043603	58	0.010
positive regulation of nucleoside metabolic process	GO:0045979	91	0.010
fat cell differentiation	GO:0045444	160	0.010
telencephalon development	GO:0021537	186	0.010
positive regulation of cell death	GO:0010942	224	0.010
protein secretion	GO:0009306	111	0.010
regulation of gtp catabolic process	GO:0033124	113	0.010
cellular calcium ion homeostasis	GO:0006874	119	0.010
sensory organ morphogenesis	GO:0090596	242	0.010
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.010
regulation of proteolysis	GO:0030162	164	0.010
intracellular receptor signaling pathway	GO:0030522	74	0.010
regulation of cell growth	GO:0001558	91	0.010
endoplasmic reticulum unfolded protein response	GO:0030968	19	0.010
anion transmembrane transport	GO:0098656	71	0.010
digestive tract development	GO:0048565	190	0.010
protein processing	GO:0016485	163	0.010

Stt3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.041
nervous system disease	DOID:863	0.041
central nervous system disease	DOID:331	0.024
neurodegenerative disease	DOID:1289	0.023
disease of metabolism	DOID:0014667	0.014
inherited metabolic disorder	DOID:655	0.014
disease of cellular proliferation	DOID:14566	0.014
cancer	DOID:162	0.012
organ system cancer	DOID:0050686	0.012

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