Mus musculus

171 known processes

Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

(Aliases: D330028K02Rik,Sha1,FLJ10518,MCPH5,Calmbp1)

Aspm biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
microtubule polymerization or depolymerizationGO:0031109260.555
Fly
organelle fissionGO:00482851700.538
microtubule cytoskeleton organizationGO:00002261570.505
female meiosis chromosome segregationGO:001632110.462
negative regulation of organelle organizationGO:0010639900.430
spindle assembly involved in mitosisGO:009030740.380
regulation of cytoskeleton organizationGO:00514931220.350
microtubule based processGO:00070172360.348
establishment of meiotic spindle orientationGO:005129610.338
Worm
negative regulation of cell cycle phase transitionGO:1901988480.338
microtubule cytoskeleton organization involved in mitosisGO:190285040.305
regulation of organelle organizationGO:00330432890.269
negative regulation of cellular component organizationGO:00511291940.263
mitotic cell cycle processGO:19030471590.256
Fly
mitotic cell cycleGO:00002781950.251
Fly
cleavage furrow formationGO:003608920.244
cellular protein catabolic processGO:00442571550.239
cell divisionGO:00513011200.226
meiotic cell cycle processGO:1903046770.222
negative regulation of microtubule polymerization or depolymerizationGO:0031111150.215
centrosome separationGO:005129940.214
heterocycle catabolic processGO:00467002800.208
regulation of cell cycleGO:00517262810.204
meiotic nuclear divisionGO:00071261150.191
nuclear divisionGO:00002801580.185
mitotic sister chromatid cohesionGO:000706410.185
mitotic cytokinesisGO:000028140.173
centrosome cycleGO:0007098230.171
mitotic chromosome condensationGO:000707610.171
regulation of microtubule based processGO:0032886520.162
metaphase plate congressionGO:005131020.161
mitotic sister chromatid segregationGO:0000070140.160
meiosis iGO:0007127600.156
regulation of cell divisionGO:0051302760.151
regulation of mitosisGO:0007088290.147
maintenance of locationGO:0051235890.137
regulation of microtubule cytoskeleton organizationGO:0070507370.137
sister chromatid segregationGO:0000819200.136
male meiosisGO:0007140370.134
macromolecule catabolic processGO:00090572810.121
microtubule polymerizationGO:0046785120.116
Fly
centrosome duplicationGO:0051298160.115
chromosome segregationGO:0007059480.111
organelle assemblyGO:00709251770.111
establishment of organelle localizationGO:00516561220.111
Worm Fly
positive regulation of chromosome segregationGO:005198440.108
protein catabolic processGO:00301632210.106
astral microtubule organizationGO:003095330.105
Fly
organonitrogen compound catabolic processGO:19015652640.105
negative regulation of cell cycleGO:00457861230.104
dna metabolic processGO:00062593030.102
spindle assembly involved in female meiosisGO:000705630.101
meiotic cell cycleGO:00513211220.100
regulation of microtubule depolymerizationGO:0031114130.100
female meiotic divisionGO:0007143210.100
protein depolymerizationGO:0051261340.099
nucleoside phosphate catabolic processGO:19012922220.099
cellular protein complex disassemblyGO:0043624360.098
glycosyl compound catabolic processGO:19016582060.097
ribonucleoside metabolic processGO:00091192450.094
regulation of protein complex disassemblyGO:0043244280.093
cellular response to dna damage stimulusGO:00069742070.092
organic cyclic compound catabolic processGO:19013612950.090
negative regulation of cytoskeleton organizationGO:0051494360.087
organelle localizationGO:00516401790.086
spindle assembly involved in meiosisGO:009030640.082
dna repairGO:00062811070.082
purine nucleotide metabolic processGO:00061633020.082
purine ribonucleoside triphosphate catabolic processGO:00092071990.079
microtubule organizing center organizationGO:0031023280.077
Fly
regulation of protein localizationGO:00328802310.077
Worm
regulation of cell cycle processGO:00105641600.077
nucleoside catabolic processGO:00091642060.076
microtubule depolymerizationGO:0007019150.073
regulation of cell cycle phase transitionGO:1901987770.073
negative regulation of microtubule depolymerizationGO:0007026130.071
cellularizationGO:000734910.069
negative regulation of nuclear divisionGO:0051784190.065
ribonucleoside catabolic processGO:00424542060.065
cellular macromolecule catabolic processGO:00442652060.064
regulation of cellular amine metabolic processGO:0033238200.064
histone threonine phosphorylationGO:003540510.062
positive regulation of mitotic sister chromatid separationGO:190197020.062
glycosyl compound metabolic processGO:19016572460.062
purine nucleoside catabolic processGO:00061522050.061
nucleoside metabolic processGO:00091162460.060
nucleoside triphosphate catabolic processGO:00091432050.060
nucleic acid phosphodiester bond hydrolysisGO:0090305490.060
ribose phosphate metabolic processGO:00196932910.059
endomembrane system organizationGO:00102561470.059
cellular ketone metabolic processGO:0042180840.059
purine nucleotide catabolic processGO:00061952110.058
ribonucleotide catabolic processGO:00092612080.058
meiotic chromosome segregationGO:0045132190.058
nucleoside phosphate metabolic processGO:00067533380.054
male gamete generationGO:00482322850.054
rho protein signal transductionGO:0007266320.051
regulation of cellular ketone metabolic processGO:0010565660.051
ribonucleoside triphosphate metabolic processGO:00091992200.051
regulation of cellular amino acid metabolic processGO:000652150.050
negative regulation of cellular catabolic processGO:0031330470.049
establishment or maintenance of cytoskeleton polarityGO:003095220.049
microtubule nucleationGO:000702020.049
Fly
cellular amino acid metabolic processGO:00065201030.048
regulation of mitotic cell cycleGO:00073461260.048
attachment of spindle microtubules to kinetochoreGO:000860840.048
positive regulation of protein modification processGO:00314012990.048
purine ribonucleotide metabolic processGO:00091502900.047
negative regulation of protein depolymerizationGO:1901880210.047
purine nucleoside metabolic processGO:00422782410.047
maintenance of location in cellGO:0051651240.046
meiotic cytokinesisGO:003320650.046
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.046
nucleotide metabolic processGO:00091173320.045
regulation of chromosome organizationGO:0033044830.044
cellular nitrogen compound catabolic processGO:00442702800.043
cellular amine metabolic processGO:0044106440.043
nucleoside triphosphate metabolic processGO:00091412300.043
regulation of meiosis iGO:006063170.043
regulation of mitotic cell cycle phase transitionGO:1901990730.043
carbohydrate derivative catabolic processGO:19011362310.043
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.042
purine ribonucleoside triphosphate metabolic processGO:00092052200.042
apoptotic signaling pathwayGO:00971903060.042
regulation of cytokine productionGO:00018172660.042
modification dependent macromolecule catabolic processGO:00436321330.042
protein complex disassemblyGO:0043241400.041
cytokinesisGO:0000910170.041
cytokinetic processGO:003250620.041
purine nucleoside monophosphate catabolic processGO:0009128580.041
amine metabolic processGO:0009308450.039
fertilizationGO:00095661270.039
nucleotide catabolic processGO:00091662170.039
mitotic spindle assembly checkpointGO:000709470.039
ubiquitin dependent protein catabolic processGO:00065111290.039
organophosphate catabolic processGO:00464342320.038
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.038
negative regulation of cell cycle processGO:0010948690.038
spindle organizationGO:0007051280.037
regulation of cellular component sizeGO:00325351210.037
regulation of microtubule polymerization or depolymerizationGO:0031110200.036
protein polymerizationGO:0051258570.036
Fly
negative regulation of meiotic cell cycle phase transitionGO:190199430.036
protein modification by small protein conjugationGO:00324461870.036
nucleobase containing small molecule metabolic processGO:00550863520.036
regulation of attachment of spindle microtubules to kinetochoreGO:005198830.035
nucleus localizationGO:0051647200.035
Fly
purine ribonucleotide catabolic processGO:00091542080.035
microtubule based movementGO:0007018840.035
positive regulation of cell divisionGO:0051781310.035
establishment of spindle orientationGO:0051294150.035
Worm Fly
protein localization to organelleGO:00333651850.035
purine nucleoside monophosphate metabolic processGO:0009126810.034
atp metabolic processGO:0046034750.034
regulation of protein maturationGO:1903317960.033
mitotic spindle organizationGO:0007052100.033
Fly
purine ribonucleoside monophosphate metabolic processGO:0009167800.033
spindle assemblyGO:0051225130.033
negative regulation of protein metabolic processGO:00512482820.033
membrane organizationGO:00610242450.032
establishment of spindle localizationGO:0051293190.032
Worm Fly
positive regulation of cellular amino acid metabolic processGO:004576430.032
positive regulation of transferase activityGO:00513471670.032
positive regulation of protein kinase activityGO:00458601440.031
actin filament polymerizationGO:0030041440.030
positive regulation of kinase activityGO:00336741550.030
ribonucleoside triphosphate catabolic processGO:00092031990.030
ribonucleotide metabolic processGO:00092592910.030
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435150.030
regulation of proteolysisGO:00301621640.030
purine nucleoside triphosphate catabolic processGO:00091462030.029
purine ribonucleoside catabolic processGO:00461302050.029
purine containing compound metabolic processGO:00725213110.029
positive regulation of organelle organizationGO:00106381280.029
striated muscle tissue developmentGO:00147062930.029
regulation of protein kinase activityGO:00458592320.028
regulation of cell cycle g2 m phase transitionGO:1902749100.028
single fertilizationGO:0007338820.028
regulation of apoptotic signaling pathwayGO:20012331970.028
purine nucleoside triphosphate metabolic processGO:00091442260.027
regulation of protein depolymerizationGO:1901879260.027
protein maturationGO:00516041760.027
regulation of cellular catabolic processGO:00313292420.027
multicellular organism growthGO:00352641610.027
synapsisGO:0007129340.027
positive regulation of cellular amine metabolic processGO:003324050.027
mitotic nuclear divisionGO:0007067480.026
regulation of protein complex assemblyGO:0043254830.026
negative regulation of protein processingGO:0010955790.026
regulation of dendritic cell cytokine productionGO:000273020.026
protein secretionGO:00093061110.026
neural tube formationGO:00018411080.026
purine ribonucleoside monophosphate catabolic processGO:0009169570.026
negative regulation of mitotic cell cycle phase transitionGO:1901991450.026
atp catabolic processGO:0006200550.026
response to radiationGO:00093141650.025
regulation of protein serine threonine kinase activityGO:00719001570.025
regulation of intracellular transportGO:00323861590.025
meiosis iiGO:000713570.025
positive regulation of mitotic metaphase anaphase transitionGO:004584220.025
blood vessel morphogenesisGO:00485142850.025
purine containing compound catabolic processGO:00725232130.024
negative regulation of mitotic cell cycleGO:0045930580.024
establishment of protein localization to organelleGO:00725941180.024
regulation of protein processingGO:0070613960.024
wnt signaling pathwayGO:00160551880.024
mitotic spindle checkpointGO:007117490.024
aromatic compound catabolic processGO:00194392860.024
embryonic epithelial tube formationGO:00018381300.024
negative regulation of protein complex disassemblyGO:0043242220.024
gonad developmentGO:00084061410.023
leukocyte mediated immunityGO:00024431740.023
vesicle transport along microtubuleGO:004749690.023
regulation of myeloid dendritic cell activationGO:003088550.023
cellular protein complex assemblyGO:00436231160.023
Fly
response to cell cycle checkpoint signalingGO:007239610.023
macromolecular complex disassemblyGO:0032984430.022
regulation of lymphocyte activationGO:00512492400.022
cell fate commitmentGO:00451652100.022
positive regulation of cell cycleGO:0045787920.022
epithelial tube formationGO:00721751300.022
purine ribonucleoside metabolic processGO:00461282410.021
gene silencingGO:0016458380.021
proteolysis involved in cellular protein catabolic processGO:00516031470.021
ras protein signal transductionGO:0007265770.021
female meiosis iGO:000714470.021
regulation of t cell activationGO:00508631700.021
regulation of cell activationGO:00508652890.021
negative regulation of cellular protein catabolic processGO:1903363220.020
intracellular protein transportGO:00068862040.020
regulation of transferase activityGO:00513382630.020
proteasomal protein catabolic processGO:0010498980.020
spindle localizationGO:0051653220.020
Worm Fly
establishment or maintenance of cell polarityGO:0007163860.020
Worm Fly
regulation of nuclear divisionGO:0051783560.020
positive regulation of protein phosphorylationGO:00019342420.020
modification dependent protein catabolic processGO:00199411330.019
immune effector processGO:00022523210.019
metaphase anaphase transition of mitotic cell cycleGO:000709190.019
regulation of anatomical structure sizeGO:00900661780.019
regulation of cell migrationGO:00303342190.019
macromolecule methylationGO:00434141200.019
placenta developmentGO:00018901400.019
development of primary sexual characteristicsGO:00451371430.019
regulation of neuron differentiationGO:00456642810.019
negative regulation of phosphorus metabolic processGO:00105631840.019
response to organic cyclic compoundGO:00140701980.019
mitotic centrosome separationGO:000710040.018
protein ubiquitinationGO:00165671710.018
actin filament organizationGO:00070151130.018
Fly
nucleoside monophosphate metabolic processGO:0009123850.018
regulation of mitotic spindle organizationGO:006023620.018
regulation of cell motilityGO:20001452360.018
developmental maturationGO:00217001930.018
regulation of chromosome segregationGO:0051983210.018
translesion synthesisGO:001998510.018
ribonucleoside monophosphate catabolic processGO:0009158570.018
protein modification by small protein conjugation or removalGO:00706472070.018
centrosome organizationGO:0051297260.017
Fly
regulation of actin filament based processGO:0032970990.017
endocytosisGO:00068971680.017
microtubule anchoringGO:003445390.017
posttranscriptional regulation of gene expressionGO:00106081550.017
spermatogenesisGO:00072832840.017
maintenance of protein location in cellGO:0032507200.017
cytokine productionGO:00018163190.017
regulation of protein catabolic processGO:00421761080.017
heterochromatin assemblyGO:003150720.017
dna biosynthetic processGO:0071897220.017
positive regulation of cellular catabolic processGO:00313311480.017
regulation of spindle organizationGO:009022420.017
actin polymerization or depolymerizationGO:0008154540.017
dephosphorylationGO:00163111290.017
dna packagingGO:0006323300.016
regulation of cellular component biogenesisGO:00440871810.016
innate immune responseGO:00450871570.016
response to organonitrogen compoundGO:00102432460.016
neural tube developmentGO:00219151600.016
positive regulation of hydrolase activityGO:00513451480.016
sensory perceptionGO:00076002450.016
negative regulation of cell sizeGO:004579230.016
negative regulation of cellular protein metabolic processGO:00322692470.016
muscle tissue developmentGO:00605373080.016
somatic diversification of immune receptors via somatic mutationGO:000256680.016
axonogenesisGO:00074092740.016
myeloid leukocyte activationGO:0002274830.016
actin cytoskeleton organizationGO:00300362200.016
Fly
negative regulation of molecular functionGO:00440922580.015
negative regulation of proteolysisGO:0045861740.015
negative regulation of mitosisGO:0045839100.015
response to light stimulusGO:00094161350.015
cation transportGO:00068123990.015
positive regulation of proteolysisGO:0045862850.015
morphogenesis of embryonic epitheliumGO:00163311590.015
t cell activationGO:00421102890.015
microtubule based transportGO:0010970500.015
lymphocyte mediated immunityGO:00024491390.015
negative regulation of protein maturationGO:1903318790.014
regulation of nucleotide metabolic processGO:00061401690.014
negative regulation of cell proliferationGO:00082852960.014
forebrain developmentGO:00309003020.014
regulation of kinase activityGO:00435492490.014
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.014
neural tube closureGO:0001843900.014
double strand break repairGO:0006302480.014
negative regulation of meiotic cell cycleGO:0051447140.014
peptidyl amino acid modificationGO:00181933360.014
meiotic dna repair synthesisGO:000071140.014
intrinsic apoptotic signaling pathwayGO:00971931320.014
single organism nuclear importGO:1902593950.014
chromatin modificationGO:00165681870.014
protein processingGO:00164851630.014
positive regulation of metaphase anaphase transition of cell cycleGO:190210120.014
small gtpase mediated signal transductionGO:0007264970.014
mapk cascadeGO:00001652810.014
dna catabolic process exonucleolyticGO:000073830.014
regulation of homeostatic processGO:00328441820.014
lateral inhibitionGO:004633110.013
cell type specific apoptotic processGO:00972852680.013
cytoskeleton dependent intracellular transportGO:0030705500.013
spindle midzone assemblyGO:005125510.013
tube closureGO:0060606910.013
regulation of nucleoside metabolic processGO:00091181300.013
membrane disassemblyGO:003039710.013
lymphocyte differentiationGO:00300982420.013
leukocyte proliferationGO:00706611720.013
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.013
negative regulation of intracellular signal transductionGO:19025321670.013
negative regulation of mitotic sister chromatid segregationGO:003304870.013
regulation of hydrolase activityGO:00513362460.013
cellular response to organonitrogen compoundGO:00714171450.013
small molecule biosynthetic processGO:00442831320.013
dna catabolic process endonucleolyticGO:0000737150.013
regulation of chromatin silencingGO:003193520.013
heterochromatin organizationGO:007082840.013
nucleoside monophosphate catabolic processGO:0009125590.012
regulation of proteasomal protein catabolic processGO:0061136460.012
regulation of cellular response to stressGO:00801351590.012
mitotic recombinationGO:000631230.012
smoothened signaling pathwayGO:00072241050.012
microtubule slidingGO:005101210.012
positive regulation of protein catabolic processGO:0045732600.012
cytoplasmic transportGO:00164822340.012
negative regulation of apoptotic signaling pathwayGO:20012341040.012
stem cell developmentGO:00488642190.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
positive regulation of cellular protein catabolic processGO:1903364340.012
oxidation reduction processGO:00551143420.012
response to fibroblast growth factorGO:0071774470.012
membrane tubulationGO:009732040.012
production of molecular mediator of immune responseGO:00024401030.012
regulation of cell projection organizationGO:00313442060.012
cellular homeostasisGO:00197252400.012
ribonucleoside monophosphate metabolic processGO:0009161800.012
negative regulation of cellular amine metabolic processGO:003323910.012
muscle cell differentiationGO:00426922610.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.011
cell maturationGO:00484691270.011
regulation of purine nucleotide catabolic processGO:00331211220.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
leukocyte differentiationGO:00025213420.011
positive regulation of nucleotide metabolic processGO:00459811140.011
mitochondrion organizationGO:00070051340.011
epithelial tube morphogenesisGO:00605623030.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
multicellular organismal signalingGO:0035637910.011
genitalia developmentGO:0048806370.011
Worm
cellular response to cytokine stimulusGO:00713451890.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.011
regulation of meiotic cell cycleGO:0051445340.011
male meiosis chromosome segregationGO:000706030.011
establishment of vesicle localizationGO:0051650810.011
cell cycle checkpointGO:0000075470.011
reactive oxygen species metabolic processGO:0072593840.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
regulation of actin cytoskeleton organizationGO:0032956840.011
positive regulation of synaptic plasticityGO:003191540.011
tube formationGO:00351481400.011
regulation of cohesin localization to chromatinGO:007192210.011
spermatid developmentGO:00072861080.011
regulation of epithelial cell proliferationGO:00506781410.011
negative regulation of sister chromatid segregationGO:003304670.011
positive regulation of nuclear divisionGO:0051785270.010
regulation of purine nucleotide metabolic processGO:19005421690.010
regulation of adaptive immune responseGO:0002819900.010
regulation of response to woundingGO:19030341890.010
chromosome separationGO:0051304140.010
regulation of sister chromatid segregationGO:0033045130.010
stem cell fate specificationGO:004886630.010
response to growth factorGO:00708481980.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.010
cell adhesionGO:00071553290.010
spermatid differentiationGO:00485151150.010
primary neural tube formationGO:0014020950.010
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051220.010
embryonic organ morphogenesisGO:00485622760.010
cellular response to biotic stimulusGO:0071216920.010
positive regulation of mitotic cell cycleGO:0045931410.010

Aspm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.127
immune system diseaseDOID:291400.127
hematopoietic system diseaseDOID:7400.127
blood coagulation diseaseDOID:124700.061
hemorrhagic diseaseDOID:221300.054
aplastic anemiaDOID:1244900.024
bone marrow diseaseDOID:496100.024
anemiaDOID:235500.024
congenital hypoplastic anemiaDOID:134200.024
fanconi s anemiaDOID:1363600.024
physical disorderDOID:008001500.017
Human
congenital nervous system abnormalityDOID:249000.017
Human
blood platelet diseaseDOID:221800.015
thoracic cancerDOID:509300.011
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
organ system cancerDOID:005068600.011