IMP: Integrative Multi-species Prediction

Mus musculus

51 known processes

Add1

adducin 1 (alpha)

(Aliases: AI256389)

Entrez: 11518
Ensembl: ENSMUSG00000029106
UniProtKB: E9Q1K3
UniProtKB: F8WHZ9
UniProtKB: Q9QYC0
UniProtKB: F8WGR0

Process Predictions
Disease Predictions

Add1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
ras protein signal transduction	GO:0007265	77	0.725
membrane organization	GO:0061024	245	0.636
modification dependent protein catabolic process	GO:0019941	133	0.620
macromolecule catabolic process	GO:0009057	281	0.617
gtp metabolic process	GO:0046039	144	0.615
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.599
regulation of cell cycle	GO:0051726	281	0.593
gtp catabolic process	GO:0006184	143	0.555
nucleotide catabolic process	GO:0009166	217	0.540
regulation of cellular ketone metabolic process	GO:0010565	66	0.528
ubiquitin dependent protein catabolic process	GO:0006511	129	0.522
regulation of protein localization	GO:0032880	231	0.497
small gtpase mediated signal transduction	GO:0007264	97	0.456
modification dependent macromolecule catabolic process	GO:0043632	133	0.454
cellular amino acid metabolic process	GO:0006520	103	0.448
actomyosin structure organization	GO:0031032	56	0.424	Fly
cellular amine metabolic process	GO:0044106	44	0.395
negative regulation of cell cycle	GO:0045786	123	0.389
plasma membrane organization	GO:0007009	90	0.384
regulation of transmembrane transport	GO:0034762	128	0.373
purine containing compound metabolic process	GO:0072521	311	0.373
cellular macromolecule catabolic process	GO:0044265	206	0.366
regulation of cellular amino acid metabolic process	GO:0006521	5	0.358
regulation of proteolysis	GO:0030162	164	0.347
engulfment of apoptotic cell	GO:0043652	3	0.346
intracellular protein transport	GO:0006886	204	0.344
cellular ketone metabolic process	GO:0042180	84	0.343
protein processing	GO:0016485	163	0.339
protein localization to membrane	GO:0072657	108	0.334
purine ribonucleoside metabolic process	GO:0046128	241	0.334
nucleoside triphosphate metabolic process	GO:0009141	230	0.331
purine containing compound catabolic process	GO:0072523	213	0.330
regulation of nucleotide metabolic process	GO:0006140	169	0.323
establishment of melanosome localization	GO:0032401	11	0.321
glial cell differentiation	GO:0010001	131	0.320
regulation of hydrolase activity	GO:0051336	246	0.320
nucleobase containing small molecule metabolic process	GO:0055086	352	0.317
microtubule cytoskeleton organization	GO:0000226	157	0.315	Fly
mapk cascade	GO:0000165	281	0.309
ribose phosphate metabolic process	GO:0019693	291	0.305
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.304
cellular protein catabolic process	GO:0044257	155	0.296
purine nucleotide metabolic process	GO:0006163	302	0.293
regulation of protein kinase activity	GO:0045859	232	0.292
regulation of ion transport	GO:0043269	215	0.289
actin cytoskeleton organization	GO:0030036	220	0.287	Human Worm Fly
ribonucleoside catabolic process	GO:0042454	206	0.285
regulation of cellular catabolic process	GO:0031329	242	0.284
purine ribonucleotide metabolic process	GO:0009150	290	0.283
glycosyl compound metabolic process	GO:1901657	246	0.279
myelination in peripheral nervous system	GO:0022011	19	0.273
asymmetric neuroblast division	GO:0055059	1	0.260
regulation of intracellular transport	GO:0032386	159	0.260
circulatory system process	GO:0003013	197	0.256
apoptotic signaling pathway	GO:0097190	306	0.253
transmission of nerve impulse	GO:0019226	76	0.253
regulation of cell projection organization	GO:0031344	206	0.251
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.250
chemotaxis	GO:0006935	247	0.246	Fly
oocyte maturation	GO:0001556	18	0.244
organophosphate catabolic process	GO:0046434	232	0.242
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.241
positive regulation of apoptotic process	GO:0043065	217	0.240
protein modification by small protein conjugation or removal	GO:0070647	207	0.238
endomembrane system organization	GO:0010256	147	0.237
establishment of organelle localization	GO:0051656	122	0.237
negative regulation of cellular component organization	GO:0051129	194	0.236	Human
amine metabolic process	GO:0009308	45	0.235
negative regulation of molecular function	GO:0044092	258	0.228
positive regulation of gtp catabolic process	GO:0033126	85	0.228
protein ubiquitination	GO:0016567	171	0.216
regulation of establishment of protein localization	GO:0070201	181	0.215
regulation of cellular amine metabolic process	GO:0033238	20	0.212
negative regulation of phosphorylation	GO:0042326	166	0.212
ribonucleotide catabolic process	GO:0009261	208	0.210
nucleoside phosphate metabolic process	GO:0006753	338	0.209
protein localization to plasma membrane	GO:0072659	57	0.209
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.206
aromatic compound catabolic process	GO:0019439	286	0.205
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.205
synapse assembly	GO:0007416	56	0.204
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.201
positive regulation of hydrolase activity	GO:0051345	148	0.200
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.198
regulation of ras protein signal transduction	GO:0046578	114	0.197
developmental maturation	GO:0021700	193	0.194
guanosine containing compound catabolic process	GO:1901069	144	0.194
protein targeting	GO:0006605	143	0.193
regulation of actin cytoskeleton organization	GO:0032956	84	0.193	Human Worm
regulation of protein targeting to membrane	GO:0090313	9	0.192
neuron projection extension	GO:1990138	64	0.189
regulation of nucleotide catabolic process	GO:0030811	122	0.187
positive regulation of cellular catabolic process	GO:0031331	148	0.186
rho protein signal transduction	GO:0007266	32	0.186
response to organic cyclic compound	GO:0014070	198	0.186
microtubule based process	GO:0007017	236	0.186	Fly
regulation of gtp catabolic process	GO:0033124	113	0.181
histone modification	GO:0016570	159	0.175
protein maturation	GO:0051604	176	0.169
nucleoside catabolic process	GO:0009164	206	0.167
ensheathment of neurons	GO:0007272	76	0.167
regulation of cell cycle process	GO:0010564	160	0.167
regulation of membrane potential	GO:0042391	192	0.166
regulation of purine nucleotide metabolic process	GO:1900542	169	0.164
adherens junction maintenance	GO:0034334	1	0.163
cell growth	GO:0016049	130	0.161
regulation of neuron differentiation	GO:0045664	281	0.160
mitotic cell cycle	GO:0000278	195	0.160
cellular homeostasis	GO:0019725	240	0.160
regulation of protein maturation	GO:1903317	96	0.159
nucleoside triphosphate catabolic process	GO:0009143	205	0.159
skin development	GO:0043588	220	0.158
regulation of protein transport	GO:0051223	163	0.158
regulation of transferase activity	GO:0051338	263	0.157
negative regulation of synapse assembly	GO:0051964	3	0.156
regulation of purine nucleotide catabolic process	GO:0033121	122	0.156
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.155
protein catabolic process	GO:0030163	221	0.155
protein polyubiquitination	GO:0000209	33	0.155
glycosyl compound catabolic process	GO:1901658	206	0.153
negative regulation of organelle organization	GO:0010639	90	0.153	Human
ribonucleoside metabolic process	GO:0009119	245	0.149
positive regulation of cell development	GO:0010720	237	0.148
positive regulation of cellular amine metabolic process	GO:0033240	5	0.146
glial cell development	GO:0021782	54	0.146
protein autophosphorylation	GO:0046777	61	0.145
developmental growth involved in morphogenesis	GO:0060560	138	0.145
negative regulation of phosphate metabolic process	GO:0045936	184	0.144
multicellular organismal signaling	GO:0035637	91	0.143
cellular nitrogen compound catabolic process	GO:0044270	280	0.142
organonitrogen compound catabolic process	GO:1901565	264	0.141
cellular response to organonitrogen compound	GO:0071417	145	0.139
nucleoside phosphate catabolic process	GO:1901292	222	0.139
peptidyl threonine modification	GO:0018210	31	0.138
regulation of cellular component biogenesis	GO:0044087	181	0.138	Human
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	40	0.136
negative regulation of nervous system development	GO:0051961	156	0.136
ribonucleotide metabolic process	GO:0009259	291	0.135
retrograde transport endosome to golgi	GO:0042147	2	0.135
regulation of neuron projection development	GO:0010975	169	0.134
axon guidance	GO:0007411	141	0.133	Fly
proteasomal protein catabolic process	GO:0010498	98	0.132
guanosine containing compound metabolic process	GO:1901068	144	0.132
positive regulation of protein phosphorylation	GO:0001934	242	0.132
regulation of cell size	GO:0008361	72	0.131
synaptic transmission	GO:0007268	329	0.131
cell adhesion	GO:0007155	329	0.130
innate immune response	GO:0045087	157	0.130
negative regulation of protein phosphorylation	GO:0001933	126	0.128
negative regulation of cell proliferation	GO:0008285	296	0.128
response to insulin	GO:0032868	100	0.127
peptidyl amino acid modification	GO:0018193	336	0.127
positive regulation of proteolysis	GO:0045862	85	0.127
carbohydrate derivative catabolic process	GO:1901136	231	0.126
neuronal action potential	GO:0019228	54	0.126
cellular response to peptide	GO:1901653	92	0.126
maintenance of location	GO:0051235	89	0.125
positive regulation of nucleotide catabolic process	GO:0030813	88	0.125
viral process	GO:0016032	41	0.125
dendrite development	GO:0016358	115	0.124
response to inactivity	GO:0014854	4	0.123
regulation of protein binding	GO:0043393	60	0.121	Human
positive regulation of nervous system development	GO:0051962	221	0.119
meiotic cell cycle	GO:0051321	122	0.118	Fly
regulation of anatomical structure size	GO:0090066	178	0.117	Human
positive regulation of gtpase activity	GO:0043547	85	0.114
regulation of cellular protein catabolic process	GO:1903362	61	0.112
organic cyclic compound catabolic process	GO:1901361	295	0.111
regulation of t cell activation	GO:0050863	170	0.111
regulation of apoptotic signaling pathway	GO:2001233	197	0.110
regulation of cell substrate adhesion	GO:0010810	73	0.110
establishment of protein localization to membrane	GO:0090150	54	0.109
melanosome localization	GO:0032400	12	0.109
peptidyl tyrosine phosphorylation	GO:0018108	143	0.109
cation transport	GO:0006812	399	0.109
axonogenesis	GO:0007409	274	0.108	Fly
heterocycle catabolic process	GO:0046700	280	0.108
blood circulation	GO:0008015	195	0.107
neuron projection guidance	GO:0097485	141	0.107	Fly
protein localization to organelle	GO:0033365	185	0.106
response to peptide	GO:1901652	136	0.105
lymphocyte homeostasis	GO:0002260	64	0.105
purine nucleoside metabolic process	GO:0042278	241	0.104
gland development	GO:0048732	330	0.104
cellular response to salt stress	GO:0071472	1	0.103
response to organonitrogen compound	GO:0010243	246	0.102
asymmetric stem cell division	GO:0098722	3	0.102
regulation of peptidase activity	GO:0052547	96	0.102
organelle assembly	GO:0070925	177	0.101	Fly
schwann cell differentiation	GO:0014037	26	0.101
organelle localization	GO:0051640	179	0.100
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.100
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.100
peptidyl serine phosphorylation	GO:0018105	74	0.100
establishment of protein localization to plasma membrane	GO:0090002	34	0.100
nucleoside metabolic process	GO:0009116	246	0.099
regulation of leukocyte differentiation	GO:1902105	159	0.099
cellular response to growth factor stimulus	GO:0071363	197	0.099
melanosome transport	GO:0032402	11	0.099
positive regulation of kinase activity	GO:0033674	155	0.099
negative regulation of multi organism process	GO:0043901	68	0.098
regulation of ral gtpase activity	GO:0032315	4	0.097
action potential	GO:0001508	78	0.096
regulation of mapk cascade	GO:0043408	248	0.096
regulation of cell motility	GO:2000145	236	0.095
positive regulation of programmed cell death	GO:0043068	218	0.095
positive regulation of cellular protein catabolic process	GO:1903364	34	0.094
negative regulation of protein metabolic process	GO:0051248	282	0.094
mitotic cell cycle process	GO:1903047	159	0.094
male gamete generation	GO:0048232	285	0.093	Fly
glucose transport	GO:0015758	56	0.093
cellular carbohydrate metabolic process	GO:0044262	119	0.092
positive regulation of cell cycle	GO:0045787	92	0.092
cellular response to hormone stimulus	GO:0032870	150	0.090
synapse organization	GO:0050808	125	0.090
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	40	0.090
t cell proliferation	GO:0042098	120	0.089
purine nucleoside catabolic process	GO:0006152	205	0.088
retina development in camera type eye	GO:0060041	119	0.088
regulation of endopeptidase activity	GO:0052548	89	0.088
positive regulation of nucleoside metabolic process	GO:0045979	91	0.088
regulation of lymphocyte proliferation	GO:0050670	117	0.088
cell type specific apoptotic process	GO:0097285	268	0.087
heart contraction	GO:0060047	93	0.087
regulation of mitotic cell cycle	GO:0007346	126	0.086
positive regulation of mapk cascade	GO:0043410	170	0.086
pigment granule localization	GO:0051875	13	0.085
cellular response to abiotic stimulus	GO:0071214	56	0.085
schwann cell development	GO:0014044	22	0.085
chromatin organization	GO:0006325	206	0.084
protein modification by small protein conjugation	GO:0032446	187	0.084
actin filament organization	GO:0007015	113	0.084	Human Fly
negative regulation of protein modification process	GO:0031400	163	0.083
regulation of lipid metabolic process	GO:0019216	118	0.083
positive regulation of nucleotide metabolic process	GO:0045981	114	0.083
g protein coupled receptor signaling pathway	GO:0007186	243	0.083
defense response to other organism	GO:0098542	197	0.082
pole plasm assembly	GO:0007315	2	0.082
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.082
regulation of nucleoside metabolic process	GO:0009118	130	0.082
regulation of protein processing	GO:0070613	96	0.081
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.080
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	62	0.080
regulation of endocytosis	GO:0030100	69	0.080
negative regulation of cellular amine metabolic process	GO:0033239	1	0.080
regulation of cell growth	GO:0001558	91	0.080
peptidyl serine modification	GO:0018209	83	0.080
peripheral nervous system development	GO:0007422	53	0.079
regulation of metal ion transport	GO:0010959	106	0.079
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	1	0.078
carbohydrate homeostasis	GO:0033500	128	0.078
regulation of intracellular protein transport	GO:0033157	82	0.078
negative regulation of cell projection organization	GO:0031345	56	0.078
ion transmembrane transport	GO:0034220	361	0.078
regulation of cell adhesion	GO:0030155	154	0.078
positive regulation of intracellular transport	GO:0032388	70	0.078
regulation of leukocyte proliferation	GO:0070663	121	0.078
regulation of lymphocyte activation	GO:0051249	240	0.077
meiotic cell cycle process	GO:1903046	77	0.077	Fly
response to growth factor	GO:0070848	198	0.077
regulation of system process	GO:0044057	200	0.076
peptidyl tyrosine modification	GO:0018212	145	0.076
gliogenesis	GO:0042063	141	0.075
negative regulation of phosphorus metabolic process	GO:0010563	184	0.075
alcohol metabolic process	GO:0006066	116	0.074
cellular response to dna damage stimulus	GO:0006974	207	0.073
cellular lipid metabolic process	GO:0044255	323	0.073
regulation of organelle organization	GO:0033043	289	0.073	Human Worm
sequestering of calcium ion	GO:0051208	18	0.073
purine ribonucleoside catabolic process	GO:0046130	205	0.073
chromatin modification	GO:0016568	187	0.073
circadian rhythm	GO:0007623	114	0.072
positive regulation of leukocyte differentiation	GO:1902107	86	0.072
sterol metabolic process	GO:0016125	58	0.071
camera type eye development	GO:0043010	266	0.071
regulation of hormone levels	GO:0010817	211	0.071
central nervous system neuron differentiation	GO:0021953	162	0.071
regulation of symbiosis encompassing mutualism through parasitism	GO:0043903	52	0.071
mitochondrion organization	GO:0007005	134	0.069
pigmentation	GO:0043473	71	0.069
establishment of glial blood brain barrier	GO:0060857	2	0.068
rhythmic process	GO:0048511	174	0.068
heart process	GO:0003015	94	0.067
protein localization to synapse	GO:0035418	11	0.067	Worm
dna alkylation	GO:0006305	43	0.067
cellular response to cytokine stimulus	GO:0071345	189	0.067
memory	GO:0007613	58	0.067	Worm
phospholipid metabolic process	GO:0006644	87	0.067
regulation of ion transmembrane transport	GO:0034765	119	0.067
regulation of proteasomal protein catabolic process	GO:0061136	46	0.067
cell fate commitment	GO:0045165	210	0.066
nucleotide metabolic process	GO:0009117	332	0.066
tissue homeostasis	GO:0001894	115	0.065
regulation of polyamine transmembrane transport	GO:1902267	5	0.065
regulation of ras gtpase activity	GO:0032318	88	0.065
positive regulation of protein transport	GO:0051222	93	0.064
regulation of binding	GO:0051098	111	0.063	Human
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.062
myelination	GO:0042552	74	0.062
carbohydrate derivative biosynthetic process	GO:1901137	183	0.062
leukocyte proliferation	GO:0070661	172	0.062
regulation of myeloid cell differentiation	GO:0045637	96	0.062
carbohydrate transport	GO:0008643	62	0.062
response to molecule of bacterial origin	GO:0002237	143	0.062
response to peptide hormone	GO:0043434	127	0.061
regulation of protein targeting	GO:1903533	61	0.061
regulation of body fluid levels	GO:0050878	162	0.061
response to lipopolysaccharide	GO:0032496	128	0.059
regulation of tight junction assembly	GO:2000810	2	0.059
regulation of defense response	GO:0031347	233	0.059
learning or memory	GO:0007611	148	0.058	Worm
cytoplasmic transport	GO:0016482	234	0.058
regulation of ral protein signal transduction	GO:0032485	4	0.057
mesoderm formation	GO:0001707	62	0.057
myeloid cell differentiation	GO:0030099	233	0.057
regulation of synaptic plasticity	GO:0048167	87	0.057
purine nucleotide catabolic process	GO:0006195	211	0.057
dna metabolic process	GO:0006259	303	0.057
regulation of cellular component size	GO:0032535	121	0.057	Human
cellular component assembly involved in morphogenesis	GO:0010927	139	0.057	Fly
leukocyte homeostasis	GO:0001776	79	0.057
establishment of spindle localization	GO:0051293	19	0.057
regulation of myeloid leukocyte differentiation	GO:0002761	58	0.056
actin filament bundle assembly	GO:0051017	40	0.056	Human
positive regulation of protein catabolic process	GO:0045732	60	0.056
lipid localization	GO:0010876	126	0.056
b cell activation	GO:0042113	161	0.056
response to granulocyte macrophage colony stimulating factor	GO:0097012	3	0.056
multi organism behavior	GO:0051705	62	0.056
regulation of t cell proliferation	GO:0042129	92	0.056
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.055
epidermis development	GO:0008544	187	0.055
generation of precursor metabolites and energy	GO:0006091	103	0.055
positive regulation of proteolysis involved in cellular protein catabolic process	GO:1903052	31	0.055
regulation of actin filament based process	GO:0032970	99	0.054	Human Worm
anion transport	GO:0006820	177	0.054
lipid modification	GO:0030258	65	0.054
cellular response to insulin stimulus	GO:0032869	78	0.054
peptidyl threonine phosphorylation	GO:0018107	31	0.054
positive regulation of growth	GO:0045927	104	0.054
jnk cascade	GO:0007254	72	0.054
calcium ion transport	GO:0006816	159	0.054
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.053
positive regulation of cell motility	GO:2000147	116	0.053
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.053
mesoderm morphogenesis	GO:0048332	64	0.053
embryonic skeletal system development	GO:0048706	120	0.052
cytosolic calcium ion homeostasis	GO:0051480	70	0.052
interspecies interaction between organisms	GO:0044419	83	0.052
positive regulation of cell cycle process	GO:0090068	61	0.052
gastrulation	GO:0007369	116	0.052
heart morphogenesis	GO:0003007	178	0.052
sequestering of metal ion	GO:0051238	19	0.052
extrinsic apoptotic signaling pathway	GO:0097191	126	0.052
endocytosis	GO:0006897	168	0.051
oxidation reduction process	GO:0055114	342	0.051
cell maturation	GO:0048469	127	0.051
regulation of cytoplasmic transport	GO:1903649	112	0.051
positive regulation of secretion by cell	GO:1903532	114	0.051
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.051
pigment granule transport	GO:0051904	12	0.051
actin filament based movement	GO:0030048	23	0.050
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.050
positive regulation of cell activation	GO:0050867	158	0.050
negative regulation of protein transport	GO:0051224	46	0.049
negative regulation of mitotic cell cycle	GO:0045930	58	0.049
response to light stimulus	GO:0009416	135	0.049
positive regulation of cell death	GO:0010942	224	0.048
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	56	0.048
positive regulation of ras gtpase activity	GO:0032320	65	0.048
attachment of spindle microtubules to kinetochore	GO:0008608	4	0.048
positive regulation of interleukin 5 secretion	GO:2000664	1	0.048
regulation of kinase activity	GO:0043549	249	0.048
positive regulation of protein export from nucleus	GO:0046827	4	0.047
cellular response to organic cyclic compound	GO:0071407	87	0.047
lymphocyte proliferation	GO:0046651	164	0.047
establishment or maintenance of cell polarity	GO:0007163	86	0.047
dna methylation	GO:0006306	43	0.046
positive regulation of leukocyte proliferation	GO:0070665	73	0.046
glucose import	GO:0046323	32	0.046
divalent inorganic cation homeostasis	GO:0072507	138	0.046
sulfur compound biosynthetic process	GO:0044272	37	0.046
organelle fission	GO:0048285	170	0.046
axon ensheathment	GO:0008366	76	0.045
negative regulation of cell development	GO:0010721	169	0.045
skeletal system development	GO:0001501	356	0.045
establishment of protein localization to organelle	GO:0072594	118	0.045
glucose homeostasis	GO:0042593	128	0.045
leukocyte differentiation	GO:0002521	342	0.045
digestive tract morphogenesis	GO:0048546	147	0.045
response to inorganic substance	GO:0010035	96	0.044
positive regulation of protein kinase activity	GO:0045860	144	0.044
regulation of cell migration	GO:0030334	219	0.044
cation homeostasis	GO:0055080	212	0.044
homeostasis of number of cells	GO:0048872	210	0.044
establishment of vesicle localization	GO:0051650	81	0.044
negative regulation of protein processing	GO:0010955	79	0.044
positive regulation of peptide hormone secretion	GO:0090277	31	0.044
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	1	0.043
regulation of cellular response to stress	GO:0080135	159	0.043
nitrogen compound transport	GO:0071705	271	0.043
positive regulation of cell projection organization	GO:0031346	95	0.043
regulation of chromatin modification	GO:1903308	57	0.043
multi organism reproductive behavior	GO:0044705	29	0.043
monosaccharide transport	GO:0015749	58	0.043
positive regulation of secretion	GO:0051047	130	0.042
sensory perception	GO:0007600	245	0.042
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.042
negative regulation of insulin receptor signaling pathway	GO:0046627	14	0.042
regulation of rho protein signal transduction	GO:0035023	71	0.042
positive regulation of neuron differentiation	GO:0045666	141	0.042
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.042
regulation of insulin receptor signaling pathway	GO:0046626	21	0.041
neural precursor cell proliferation	GO:0061351	121	0.041
positive regulation of neuron projection development	GO:0010976	79	0.041
regulation of secretion	GO:0051046	274	0.041
single organism cell adhesion	GO:0098602	156	0.041
wound healing	GO:0042060	157	0.041
digestive system development	GO:0055123	200	0.041
protein targeting to membrane	GO:0006612	20	0.041
cell junction maintenance	GO:0034331	4	0.040
calcium ion homeostasis	GO:0055074	127	0.040
regulation of cysteine type endopeptidase activity	GO:2000116	65	0.040
photoreceptor cell differentiation	GO:0046530	52	0.040
negative regulation of stress fiber assembly	GO:0051497	4	0.040
multi multicellular organism process	GO:0044706	109	0.040
positive regulation of lymphocyte activation	GO:0051251	140	0.040
glycogen metabolic process	GO:0005977	32	0.039
oocyte anterior posterior axis specification	GO:0007314	2	0.039
single fertilization	GO:0007338	82	0.039
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	68	0.039
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.039
myeloid leukocyte differentiation	GO:0002573	119	0.039
regulation of multi organism process	GO:0043900	111	0.039
protein import	GO:0017038	101	0.039
negative regulation of protein maturation	GO:1903318	79	0.039
polysaccharide metabolic process	GO:0005976	39	0.039
organic hydroxy compound metabolic process	GO:1901615	203	0.038
regulation of t helper 2 cell cytokine production	GO:2000551	3	0.038
cell division	GO:0051301	120	0.038	Fly
positive regulation of fibroblast growth factor receptor signaling pathway	GO:0045743	3	0.038
negative regulation of transposition	GO:0010529	2	0.038
regulation of protein catabolic process	GO:0042176	108	0.038
cell cell junction organization	GO:0045216	72	0.038
zymogen activation	GO:0031638	41	0.038
regulation of glucose transport	GO:0010827	32	0.037
positive regulation of protein modification process	GO:0031401	299	0.037
cellular response to granulocyte macrophage colony stimulating factor stimulus	GO:0097011	3	0.037
spindle localization	GO:0051653	22	0.037
insulin receptor signaling pathway	GO:0008286	49	0.037
positive regulation of oocyte development	GO:0060282	4	0.037
response to alkaloid	GO:0043279	34	0.037
negative regulation of kinase activity	GO:0033673	81	0.037
inorganic cation transmembrane transport	GO:0098662	207	0.037
regulation of extent of cell growth	GO:0061387	52	0.036
carboxylic acid biosynthetic process	GO:0046394	86	0.036
reactive oxygen species biosynthetic process	GO:1903409	8	0.036
positive regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032436	23	0.036
positive regulation of t helper 2 cell activation	GO:2000570	2	0.036
spermatogenesis	GO:0007283	284	0.036	Fly
body morphogenesis	GO:0010171	45	0.036
positive regulation of reactive oxygen species biosynthetic process	GO:1903428	2	0.036
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.036
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.036
fatty acid metabolic process	GO:0006631	121	0.036
nucleus localization	GO:0051647	20	0.036
cellular response to parathyroid hormone stimulus	GO:0071374	2	0.036
divalent inorganic cation transport	GO:0072511	178	0.035
t helper 2 cell activation	GO:0035712	2	0.035
carbohydrate metabolic process	GO:0005975	230	0.035
microtubule based movement	GO:0007018	84	0.035
digestive tract development	GO:0048565	190	0.035
axon cargo transport	GO:0008088	33	0.035
ossification	GO:0001503	216	0.035
regulation of calcium ion transport	GO:0051924	69	0.035
leukocyte migration	GO:0050900	124	0.035
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.035
metal ion homeostasis	GO:0055065	189	0.034
production of molecular mediator of immune response	GO:0002440	103	0.034
cellular polysaccharide metabolic process	GO:0044264	38	0.034
phagocytosis	GO:0006909	66	0.034
multicellular organism growth	GO:0035264	161	0.034
cd4 positive alpha beta t cell cytokine production	GO:0035743	4	0.033
protein deubiquitination	GO:0016579	19	0.033
dna methylation on cytosine	GO:0032776	5	0.033
epithelial cell proliferation	GO:0050673	174	0.033
single organismal cell cell adhesion	GO:0016337	131	0.033
purine ribonucleotide catabolic process	GO:0009154	208	0.033
protein dna complex disassembly	GO:0032986	1	0.033
protein localization to nucleus	GO:0034504	121	0.033
sensory organ morphogenesis	GO:0090596	242	0.033
regulation of peptidyl serine phosphorylation	GO:0033135	39	0.033
response to epidermal growth factor	GO:0070849	4	0.033
dna modification	GO:0006304	50	0.032
macromolecule methylation	GO:0043414	120	0.032
negative regulation of lipid metabolic process	GO:0045833	30	0.032
cellular metal ion homeostasis	GO:0006875	151	0.032

Add1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.043	Human
	nervous system disease	DOID:863	0	0.043

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