Mus musculus

107 known processes

Lta

lymphotoxin A

(Aliases: MGC117668,LTalpha,TNF-beta,Ltx,Tnfsf1b,LT,LT-[a],Tnfb,LT[a],TNFSF1,LT-alpha,hlb382)

Lta biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lymph node developmentGO:0048535180.998
positive regulation of chronic inflammatory responseGO:000267840.995
positive regulation of icosanoid secretionGO:003230570.994
Mouse
icosanoid secretionGO:0032309120.994
Mouse
interleukin 5 secretionGO:007260320.993
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.993
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.993
immunoglobulin secretionGO:0048305170.992
Mouse
regulation of corticotropin releasing hormone secretionGO:004339720.992
Mouse
interleukin 10 secretionGO:007260840.991
prostaglandin transportGO:001573270.990
Mouse
lymphocyte differentiationGO:00300982420.988
Mouse
positive regulation of translational initiation by ironGO:004599420.988
Mouse
regulation of translational initiation by ironGO:000644720.987
Mouse
i kappab kinase nf kappab signalingGO:0007249850.985
Mouse
somatic diversification of immunoglobulinsGO:0016445430.984
Mouse
positive regulation of adaptive immune responseGO:0002821610.982
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.982
regulation of fever generation by regulation of prostaglandin secretionGO:007181020.982
Mouse
positive regulation of translational initiationGO:004594840.981
Mouse
regulation of b cell proliferationGO:0030888390.979
positive regulation of leukocyte proliferationGO:0070665730.977
regulation of b cell activationGO:0050864810.977
cytokine mediated signaling pathwayGO:00192211150.975
Mouse
regulation of interleukin 6 productionGO:0032675550.972
Mouse
regulation of cell activationGO:00508652890.967
Mouse
regulation of t cell activationGO:00508631700.965
Mouse
positive regulation of fever generation by positive regulation of prostaglandin secretionGO:007181220.964
Mouse
extracellular structure organizationGO:00430621480.962
Mouse
regulation of leukocyte proliferationGO:00706631210.952
cellular response to amino acid stimulusGO:0071230290.950
Mouse
interleukin 13 secretionGO:007261120.949
positive regulation of osteoclast developmentGO:200120630.945
Mouse
growth of symbiont involved in interaction with hostGO:0044116230.941
regulation of inflammatory response to antigenic stimulusGO:0002861210.937
tumor necrosis factor mediated signaling pathwayGO:0033209130.935
Mouse
positive regulation of cell activationGO:00508671580.932
Mouse
fatty acid derivative transportGO:1901571140.931
Mouse
lymphocyte mediated immunityGO:00024491390.931
heat generationGO:0031649130.927
Mouse
lymphocyte migrationGO:0072676260.924
Mouse
pigment metabolic processGO:0042440320.924
Fly
negative regulation of growth of symbiont in hostGO:0044130190.924
b cell activationGO:00421131610.923
Mouse
regulation of fatty acid transportGO:2000191100.923
Mouse
corticotropin releasing hormone secretionGO:004339620.920
Mouse
leukocyte mediated immunityGO:00024431740.919
necroptotic signaling pathwayGO:009752730.918
Mouse
acid secretionGO:0046717330.918
Mouse
regulation of chronic inflammatory response to antigenic stimulusGO:000287430.911
ensheathment of neuronsGO:0007272760.911
immunoglobulin mediated immune responseGO:0016064690.910
alpha beta t cell proliferationGO:0046633210.906
positive regulation of b cell activationGO:0050871490.906
positive regulation of fever generationGO:003162260.903
Mouse
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.903
Mouse
regulation of interleukin 13 secretionGO:200066520.901
positive regulation of isotype switching to igg isotypesGO:004830470.899
positive regulation of interleukin 12 productionGO:0032735210.899
negative regulation of interleukin 10 secretionGO:200118020.898
t cell migrationGO:0072678190.898
Mouse
immune response activating cell surface receptor signaling pathwayGO:0002429720.895
interleukin 12 productionGO:0032615320.895
positive regulation of lymphocyte activationGO:00512511400.894
Mouse
regulation of cytokine productionGO:00018172660.892
regulation of response to woundingGO:19030341890.892
negative regulation of interleukin 13 productionGO:003269620.890
defense response to bacteriumGO:00427421190.885
negative regulation of multi organism processGO:0043901680.884
metal ion homeostasisGO:00550651890.883
Mouse
regulation of anion transportGO:0044070270.878
Mouse
dna recombinationGO:0006310920.876
Mouse
positive regulation of b cell proliferationGO:0030890240.876
regulation of interleukin 10 secretionGO:200117940.875
carboxylic acid transportGO:00469421000.873
Mouse
positive regulation of t cell activationGO:00508701010.870
Mouse
cytokine production involved in immune responseGO:0002367340.870
leukocyte proliferationGO:00706611720.869
Mouse
t cell receptor signaling pathwayGO:0050852460.869
leukocyte differentiationGO:00025213420.868
Mouse
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.866
Mouse
regulation of adaptive immune responseGO:0002819900.861
response to tumor necrosis factorGO:0034612260.860
Mouse
positive regulation of myoblast differentiationGO:004566380.859
Mouse
extrinsic apoptotic signaling pathwayGO:00971911260.854
Mouse Fly
positive regulation of immunoglobulin mediated immune responseGO:0002891260.850
positive regulation of immune effector processGO:00026991070.849
growth of symbiont in hostGO:0044117230.848
positive regulation of lymphocyte proliferationGO:0050671700.848
t cell proliferationGO:00420981200.844
fever generationGO:000166070.841
Mouse
positive regulation of organic acid transportGO:0032892110.840
Mouse
negative regulation of growth of symbiont involved in interaction with hostGO:0044146190.839
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.838
Mouse
positive regulation of humoral immune response mediated by circulating immunoglobulinGO:000292560.838
positive regulation of inflammatory response to antigenic stimulusGO:0002863110.833
lymphocyte costimulationGO:0031294150.828
Mouse
programmed necrotic cell deathGO:0097300280.826
Mouse
negative regulation of interleukin 5 productionGO:003271440.823
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.822
Mouse
positive regulation of leukocyte mediated immunityGO:0002705700.817
positive regulation of heat generationGO:003165270.813
Mouse
t cell chemotaxisGO:001081860.808
Mouse
humoral immune responseGO:0006959570.800
skeletal muscle fiber developmentGO:0048741580.799
Mouse
cytokine productionGO:00018163190.797
positive regulation of lipid transportGO:0032370220.795
Mouse
somatic cell dna recombinationGO:0016444510.792
Mouse
regulation of leukocyte mediated immunityGO:00027031040.788
dephosphorylationGO:00163111290.784
Mouse
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.782
regulation of lymphocyte mediated immunityGO:0002706840.775
axon ensheathmentGO:0008366760.771
dendritic cell differentiationGO:0097028260.769
acute phase responseGO:0006953100.765
Mouse
regulation of lymphocyte differentiationGO:00456191070.763
regulation of lymphocyte activationGO:00512492400.763
Mouse
action potentialGO:0001508780.762
regulation of establishment of protein localizationGO:00702011810.759
Mouse
regulation of t cell proliferationGO:0042129920.757
regulation of acute inflammatory responseGO:0002673270.751
Mouse
regulation of skeletal muscle fiber developmentGO:0048742360.750
Mouse
positive regulation of lymphocyte mediated immunityGO:0002708620.749
positive regulation of corticotropin releasing hormone secretionGO:005146610.748
Mouse
regulation of cytokine secretionGO:0050707610.748
regulation of lipid transportGO:0032368360.746
Mouse
regulation of fever generationGO:003162060.745
Mouse
regulation of lymphocyte proliferationGO:00506701170.740
adaptive immune responseGO:00022501550.737
regulation of cytokine biosynthetic processGO:0042035590.736
regulation of immunoglobulin secretionGO:0051023120.730
Mouse
cellular response to tumor necrosis factorGO:0071356210.724
Mouse
cytokine biosynthetic processGO:0042089680.722
glial cell apoptotic processGO:003434930.722
multicellular organismal signalingGO:0035637910.719
organic acid transportGO:00158491010.718
Mouse
positive regulation of b cell mediated immunityGO:0002714260.718
production of molecular mediator of immune responseGO:00024401030.714
Mouse
lipid transportGO:0006869980.710
Mouse
regulation of immunoglobulin mediated immune responseGO:0002889370.709
cell chemotaxisGO:0060326810.708
Mouse
t cell activationGO:00421102890.708
Mouse
regulation of cytokine secretion involved in immune responseGO:000273940.707
positive regulation of interferon gamma productionGO:0032729390.707
b cell mediated immunityGO:0019724710.702
regulation of interleukin 5 secretionGO:200066220.696
positive regulation of cytokine productionGO:00018191740.685
regulation of lymphocyte migrationGO:2000401140.673
Mouse
positive regulation of response to woundingGO:1903036660.673
regulation of homeostatic processGO:00328441820.668
Mouse
positive regulation of hair follicle developmentGO:005179860.666
Mouse
positive regulation of lymphocyte migrationGO:2000403110.665
Mouse
regulation of growth of symbiont in hostGO:0044126190.657
regulation of prostaglandin secretionGO:003230650.654
Mouse
positive regulation of fatty acid transportGO:200019380.651
Mouse
b cell activation involved in immune responseGO:0002312500.650
Mouse
t cell selectionGO:0045058340.650
protein localization to nucleusGO:00345041210.648
Mouse
negative regulation of interleukin 13 secretionGO:200066610.641
defense response to other organismGO:00985421970.640
isotype switchingGO:0045190360.632
Mouse
chronic inflammatory responseGO:000254490.628
regulation of alpha beta t cell proliferationGO:0046640180.628
negative regulation of t cell activationGO:0050868650.626
protein kinase b signalingGO:0043491740.617
Mouse
negative regulation of odontogenesis of dentin containing toothGO:004248910.612
positive regulation of defense responseGO:00313491240.612
necroptotic processGO:0070266210.609
Mouse
activation of cysteine type endopeptidase activityGO:0097202270.605
Mouse
zymogen activationGO:0031638410.597
Mouse
growth involved in symbiotic interactionGO:0044110230.597
lymphocyte chemotaxisGO:0048247100.595
Mouse
neuronal action potentialGO:0019228540.594
regulation of protein transportGO:00512231630.592
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.591
positive regulation of cytokine secretionGO:0050715410.584
immune response activating signal transductionGO:00027571160.583
negative regulation of myoblast differentiationGO:0045662180.581
Mouse
monocarboxylic acid transportGO:0015718440.580
Mouse
t cell differentiation in thymusGO:0033077770.580
cellular divalent inorganic cation homeostasisGO:00725031270.579
alpha beta t cell activationGO:0046631910.565
epithelial cell proliferationGO:00506731740.564
Mouse
negative regulation of osteoblast differentiationGO:0045668300.562
Mouse
regulation of branching involved in salivary gland morphogenesisGO:0060693110.556
Mouse
activation of jun kinase activityGO:0007257150.555
Mouse
immune effector processGO:00022523210.553
t cell costimulationGO:0031295140.552
Mouse
apoptotic signaling pathwayGO:00971903060.550
Mouse Fly
positive regulation of peptide hormone secretionGO:0090277310.546
Mouse
positive regulation of prostaglandin secretionGO:003230850.543
Mouse
positive regulation of secretionGO:00510471300.542
Mouse
positive regulation of peptide secretionGO:0002793330.541
Mouse
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.537
Mouse
muscle cell developmentGO:00550011330.535
Mouse
skin developmentGO:00435882200.535
Mouse
alpha beta t cell differentiationGO:0046632690.534
positive regulation of cytokine biosynthetic processGO:0042108400.533
icosanoid transportGO:0071715140.528
Mouse
b cell differentiationGO:0030183780.527
Mouse
regulation of interleukin 2 productionGO:0032663280.527
positive regulation of jun kinase activityGO:0043507300.522
Mouse
regulation of b cell mediated immunityGO:0002712370.522
regulation of protein secretionGO:0050708820.519
Mouse
positive regulation of jnk cascadeGO:0046330460.512
Mouse
protein homooligomerizationGO:0051260430.510
Mouse
translational initiationGO:0006413240.502
Mouse
negative regulation of interleukin 5 secretionGO:200066310.497
mammary gland alveolus developmentGO:0060749220.496
Mouse
regulation of reactive oxygen species metabolic processGO:2000377400.493
Mouse
positive regulation of t cell costimulationGO:200052520.482
stress activated protein kinase signaling cascadeGO:0031098810.479
Mouse Fly
regulation of peptide hormone secretionGO:0090276750.477
Mouse
regulation of translational initiationGO:0006446150.475
Mouse
defense response to virusGO:0051607680.468
regulation of gliogenesisGO:0014013500.468
Rat
osteoclast proliferationGO:000215840.467
Mouse
lymphocyte proliferationGO:00466511640.466
cellular homeostasisGO:00197252400.465
Fly
interspecies interaction between organismsGO:0044419830.464
protein secretionGO:00093061110.462
Mouse
positive regulation of secretion by cellGO:19035321140.461
Mouse
alpha beta t cell activation involved in immune responseGO:0002287310.461
leukocyte activation involved in immune responseGO:00023661260.456
Mouse
hair follicle developmentGO:0001942850.454
Mouse
prostaglandin secretionGO:003231050.453
Mouse
regulation of lymphocyte chemotaxisGO:190162360.453
Mouse
positive regulation of intracellular transportGO:0032388700.452
Mouse
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.447
Mouse
somatic diversification of immune receptorsGO:0002200530.446
Mouse
transmission of nerve impulseGO:0019226760.444
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.443
dna metabolic processGO:00062593030.441
Mouse
myeloid cell differentiationGO:00300992330.436
Mouse
positive regulation of t cell differentiationGO:0045582520.433
temperature homeostasisGO:0001659260.432
Mouse
positive regulation of peptidase activityGO:0010952490.426
Mouse
regulation of alpha beta t cell activationGO:0046634530.425
cytokine secretion involved in immune responseGO:000237460.423
cellular calcium ion homeostasisGO:00068741190.421
cellular response to lipidGO:00713961450.420
Mouse
skeletal muscle organ developmentGO:00605381630.404
Mouse
odontogenesisGO:0042476780.403
circadian rhythmGO:00076231140.403
regulation of defense responseGO:00313472330.402
defense response to gram positive bacteriumGO:0050830500.400
regulation of humoral immune responseGO:0002920220.396
inflammatory responseGO:00069542440.395
calcium ion homeostasisGO:00550741270.394
Mouse
cellular metal ion homeostasisGO:00068751510.393
b cell apoptotic processGO:0001783190.393
regulation of sequence specific dna binding transcription factor activityGO:00510901060.389
Mouse
immune complex clearanceGO:000243420.387
positive regulation of cellular amine metabolic processGO:003324050.386
response to molecule of bacterial originGO:00022371430.383
Zebrafish Mouse Rat
regulation of protein serine threonine kinase activityGO:00719001570.383
Mouse
divalent inorganic cation homeostasisGO:00725071380.382
Mouse
lymphocyte activation involved in immune responseGO:0002285930.381
Mouse
regulation of immunoglobulin productionGO:0002637420.379
Mouse
negative regulation of alkaline phosphatase activityGO:001069330.378
Mouse
immune response regulating cell surface receptor signaling pathwayGO:0002768800.378
t cell differentiationGO:00302171740.377
positive regulation of inflammatory responseGO:0050729470.370
fatty acid transportGO:0015908280.366
Mouse
eosinophil degranulationGO:004330810.361
positive regulation of map kinase activityGO:0043406840.359
Mouse
cytokine metabolic processGO:0042107710.357
mammary gland lobule developmentGO:0061377220.352
Mouse
muscle tissue developmentGO:00605373080.351
Mouse
regulation of oligodendrocyte differentiationGO:0048713230.347
syncytium formation by plasma membrane fusionGO:0000768420.345
Mouse
protein maturationGO:00516041760.343
Mouse
regulation of ion transportGO:00432692150.343
Mouse
epidermis developmentGO:00085441870.338
Mouse
antigen receptor mediated signaling pathwayGO:0050851640.337
positive regulation of cytokine production involved in immune responseGO:0002720190.333
cellular response to cytokine stimulusGO:00713451890.328
Mouse
regulation of membrane potentialGO:00423911920.322
positive regulation of homeostatic processGO:0032846640.320
Mouse
myelinationGO:0042552740.320
defense response to gram negative bacteriumGO:0050829280.319
Fly
engulfment of apoptotic cellGO:004365230.318
Fly
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.318
regulation of peptide transportGO:0090087910.316
Mouse
cytoplasmic transportGO:00164822340.315
Mouse
positive regulation of monocyte chemotaxisGO:009002620.315
positive regulation of ion transportGO:0043270650.315
Mouse
regulation of cytokine production involved in immune responseGO:0002718260.313
positive regulation of hormone secretionGO:0046887380.312
Mouse
positive regulation of gliogenesisGO:0014015270.311
Rat
b cell proliferationGO:0042100530.310
amide transportGO:00428861380.309
Mouse
regulation of proteolysisGO:00301621640.304
Mouse
mature dendritic cell differentiationGO:009702930.302
cytokine secretionGO:0050663720.301
positive regulation of protein kinase b signalingGO:0051897320.299
Mouse
gliogenesisGO:00420631410.298
Rat
positive regulation of acute inflammatory responseGO:0002675160.298
Mouse
gland developmentGO:00487323300.298
Zebrafish Mouse
negative regulation of glucose transportGO:001082990.298
Mouse
positive regulation of t cell migrationGO:2000406100.297
Mouse
transcription factor import into nucleusGO:0042991260.297
Mouse
cell type specific apoptotic processGO:00972852680.295
striated muscle cell developmentGO:00550021250.295
Mouse
regulation of monocyte chemotaxisGO:009002530.295
regulation of intracellular transportGO:00323861590.294
Mouse
regulation of glucose importGO:0046324260.292
Mouse
t helper 2 cell cytokine productionGO:003574540.292
regulation of t cell costimulationGO:200052320.289
cell cell recognitionGO:0009988440.285
regulation of protein localizationGO:00328802310.284
Mouse
positive regulation of interleukin 6 productionGO:0032755370.281
Mouse
cellular chemical homeostasisGO:00550822150.280
regulation of inflammatory responseGO:00507271470.280
negative regulation of alpha beta t cell activationGO:0046636180.277
regulation of interleukin 12 productionGO:0032655300.270
regulation of eosinophil degranulationGO:004330910.270
establishment of protein localization to organelleGO:00725941180.270
Mouse
t cell extravasationGO:007268340.267
somatic recombination of immunoglobulin gene segmentsGO:0016447420.265
Mouse
regulation of monocyte extravasationGO:200043720.263
positive regulation of cytokine secretion involved in immune responseGO:000274120.263
regulation of hair follicle developmentGO:005179790.262
Mouse
muscle fiber developmentGO:0048747760.261
Mouse
positive regulation of stress activated mapk cascadeGO:0032874480.259
Mouse
modulation of growth of symbiont involved in interaction with hostGO:0044144190.259
positive regulation of monocyte extravasationGO:200043910.258
negative regulation of response to woundingGO:1903035770.258
regulation of type 2 immune responseGO:0002828180.255
cellular ion homeostasisGO:00068731650.254
anatomical structure homeostasisGO:00602491450.252
Mouse Fly
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.249
acute inflammatory responseGO:0002526410.247
Mouse
regulation of jnk cascadeGO:0046328620.243
Mouse
oligodendrocyte differentiationGO:0048709530.243
positive regulation of cell deathGO:00109422240.243
Mouse Rat
isotype switching to igg isotypesGO:0048291100.240
regulation of stress activated mapk cascadeGO:0032872690.240
Mouse
regulation of myoblast differentiationGO:0045661290.236
Mouse
epithelial cell proliferation involved in salivary gland morphogenesisGO:006066470.232
Mouse
regulation of cellular amino acid metabolic processGO:000652150.230
cellular amino acid metabolic processGO:00065201030.230
cation homeostasisGO:00550802120.225
Mouse
positive regulation of cell developmentGO:00107202370.224
Mouse Rat
positive regulation of chronic inflammatory response to antigenic stimulusGO:000287620.224
eosinophil activationGO:004330710.221
regulation of interferon gamma productionGO:0032649570.218
extracellular matrix organizationGO:00301981470.216
Mouse
negative regulation of b cell proliferationGO:0030889130.215
circadian temperature homeostasisGO:006008620.214
response to amino acidGO:0043200370.214
Mouse
cellular response to lipopolysaccharideGO:0071222770.214
Mouse
myeloid dendritic cell differentiationGO:0043011160.214
regulation of vasculature developmentGO:1901342880.214
antibacterial peptide productionGO:000277820.214
regulation of t cell extravasationGO:200040730.212
mammary gland epithelial cell proliferationGO:0033598240.212
Mouse
eosinophil mediated immunityGO:000244710.210
multicellular organismal homeostasisGO:00488711640.210
Mouse
positive regulation of interleukin 2 productionGO:0032743190.207
negative regulation of b cell activationGO:0050869270.205
positive regulation of translationGO:0045727190.205
Mouse
negative regulation of ossificationGO:0030279490.202
Mouse
regulation of dna recombinationGO:0000018340.201
leukocyte migrationGO:00509001240.201
Mouse
chronic inflammatory response to antigenic stimulusGO:000243930.201
negative regulation of defense responseGO:0031348770.201
activation of immune responseGO:00022531380.200
posttranscriptional regulation of gene expressionGO:00106081550.200
Mouse
regulation of secretionGO:00510462740.199
Mouse
positive regulation of leukocyte differentiationGO:1902107860.199
Mouse
regulation of secretion by cellGO:19035302490.199
Mouse
cd8 positive alpha beta t cell extravasationGO:003569730.198
regulation of multi organism processGO:00439001110.198
regulation of protein kinase activityGO:00458592320.198
Mouse
helper t cell chemotaxisGO:003570410.197
regulation of glial cell differentiationGO:0045685410.196
immune response regulating signaling pathwayGO:00027641250.196
regulation of isotype switching to igg isotypesGO:0048302100.196
positive regulation of humoral immune responseGO:0002922110.195
anion transportGO:00068201770.192
Mouse
neuromuscular synaptic transmissionGO:0007274160.190
Fly
striated muscle tissue developmentGO:00147062930.189
Mouse
positive regulation of protein transportGO:0051222930.189
Mouse
positive regulation of programmed cell deathGO:00430682180.188
Mouse Rat
eosinophil activation involved in immune responseGO:000227810.188
cytosolic calcium ion homeostasisGO:0051480700.186
regulation of epithelial cell proliferationGO:00506781410.185
cell fate commitmentGO:00451652100.183
Fly
exocrine system developmentGO:0035272450.179
Mouse
negative regulation of macrophage apoptotic processGO:200011030.178
response to acid chemicalGO:00011011110.177
Mouse
positive regulation of antibacterial peptide biosynthetic processGO:000696310.176
cellular response to dna damage stimulusGO:00069742070.175
Mouse
hexose transportGO:0008645560.171
Mouse
regulation of t helper 1 type immune responseGO:0002825170.171
t cell activation involved in immune responseGO:0002286430.167
regulation of peptide secretionGO:0002791770.166
Mouse
neuron apoptotic processGO:00514021420.165
positive regulation of chemotaxisGO:0050921380.165
Mouse
regulation of dendritic cell chemotaxisGO:200050810.164
regulation of interleukin 6 biosynthetic processGO:0045408110.163
cell activation involved in immune responseGO:00022631260.163
Mouse
gtp metabolic processGO:00460391440.161
tissue remodelingGO:00487711020.160
Mouse
stress activated mapk cascadeGO:0051403800.160
Mouse Fly
thymic t cell selectionGO:0045061220.159
positive regulation of osteoclast differentiationGO:0045672150.159
Mouse
protein importGO:00170381010.159
Mouse
t cell differentiation involved in immune responseGO:0002292300.159
positive regulation of kinase activityGO:00336741550.158
Mouse
calcium ion transportGO:00068161590.157
response to organonitrogen compoundGO:00102432460.156
Mouse
regulation of t cell chemotaxisGO:001081950.156
Mouse
positive regulation of protein secretionGO:0050714520.156
syncytium formationGO:0006949430.156
Mouse
cd4 positive alpha beta t cell differentiationGO:0043367410.154
regulation of protein localization to nucleusGO:1900180600.153
Mouse
cdc42 protein signal transductionGO:003248800.153
microglial cell activation involved in immune responseGO:000228210.153
molting cycleGO:0042303900.153
Mouse
jnk cascadeGO:0007254720.152
Mouse Fly
regulation of b cell differentiationGO:0045577230.152
regulation of hydrolase activityGO:00513362460.152
Mouse
positive regulation of t cell receptor signaling pathwayGO:005086240.151
regulation of myotube differentiationGO:0010830620.150
Mouse
interferon gamma productionGO:0032609670.149
negative regulation of muscle cell differentiationGO:0051148330.149
Mouse
negative regulation of dephosphorylationGO:003530590.147
Mouse
negative regulation of cell activationGO:00508661110.143
positive regulation of reactive oxygen species biosynthetic processGO:190342820.143
intracellular protein transportGO:00068862040.140
Mouse
purine nucleoside catabolic processGO:00061522050.140
regulation of cd4 positive alpha beta t cell activationGO:2000514240.139
positive regulation of cytosolic calcium ion concentrationGO:0007204650.138
regulation of endothelial cell chemotaxisGO:200102610.138
retinal cell programmed cell deathGO:004666680.137
Mouse
regulation of organic acid transportGO:0032890160.136
Mouse
cellular response to external stimulusGO:0071496880.133
negative regulation of lymphocyte activationGO:0051250910.132
negative regulation of immune effector processGO:0002698550.132
positive regulation of alpha beta t cell activationGO:0046635390.130
protein processingGO:00164851630.130
Mouse
glucose metabolic processGO:0006006920.129
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.127
Mouse
reactive oxygen species metabolic processGO:0072593840.127
Mouse
organophosphate catabolic processGO:00464342320.126
peptide transportGO:00158331330.125
Mouse
t cell mediated immunityGO:0002456500.124
positive regulation of hydrolase activityGO:00513451480.124
Mouse
guanosine containing compound metabolic processGO:19010681440.124
myotube cell developmentGO:0014904600.123
Mouse
regulation of cytoplasmic transportGO:19036491120.122
Mouse
telencephalon developmentGO:00215371860.122
interleukin 6 productionGO:0032635580.121
Mouse
regulation of neutrophil chemotaxisGO:0090022140.121
regulation of cell motilityGO:20001452360.121
Mouse
positive regulation of t cell proliferationGO:0042102520.119
myeloid leukocyte activationGO:0002274830.117
positive regulation of alpha beta t cell differentiationGO:0046638280.117
negative regulation of molecular functionGO:00440922580.117
Mouse
response to lipopolysaccharideGO:00324961280.116
Zebrafish Mouse Rat
positive regulation of hair cycleGO:004263570.116
Mouse
regulation of dephosphorylationGO:0035303180.116
Mouse
single organism cell adhesionGO:00986021560.116
regulation of apoptotic signaling pathwayGO:20012331970.115
cellular response to molecule of bacterial originGO:0071219830.115
Mouse
positive regulation of t cell chemotaxisGO:001082050.115
Mouse
natural killer cell activationGO:0030101440.115
protein complex localizationGO:0031503190.114
Mouse
asymmetric protein localizationGO:0008105110.114
Fly
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.114
negative regulation of eosinophil degranulationGO:004331010.113
regulation of cd4 positive alpha beta t cell differentiationGO:0043370210.113
glial cell differentiationGO:00100011310.112
positive regulation of cytoplasmic transportGO:1903651400.111
Mouse
positive regulation of oligodendrocyte differentiationGO:004871490.111
cytosolic calcium ion transportGO:0060401480.111
ossificationGO:00015032160.110
Mouse
regulation of jun kinase activityGO:0043506400.110
Mouse
leukocyte apoptotic processGO:0071887710.110
negative regulation of odontogenesisGO:004248330.109
regulation of cellular response to stressGO:00801351590.109
Mouse
regulation of nucleocytoplasmic transportGO:0046822730.108
Mouse
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.107
bone resorptionGO:0045453380.107
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.107
regulation of glucose transportGO:0010827320.106
Mouse
cd4 positive alpha beta t cell cytokine productionGO:003574340.106
regulation of alpha beta t cell differentiationGO:0046637350.105
positive regulation of antigen processing and presentationGO:0002579100.105
osteoclast developmentGO:003603590.105
Mouse
interleukin 1 secretionGO:0050701160.105
regulation of t helper 2 cell cytokine productionGO:200055130.104
b cell receptor signaling pathwayGO:0050853200.104

Lta disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
bone diseaseDOID:008000100.122
disease of anatomical entityDOID:700.122
musculoskeletal system diseaseDOID:1700.122
connective tissue diseaseDOID:6500.122