Mus musculus

0 known processes

Lrrc8e

leucine rich repeat containing 8 family, member E

(Aliases: C87354,MGC91131,1810049O03Rik)

Lrrc8e biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201030.077
mapk cascadeGO:00001652810.056
ras protein signal transductionGO:0007265770.054
regulation of transferase activityGO:00513382630.053
regulation of mapk cascadeGO:00434082480.053
amine metabolic processGO:0009308450.053
cell adhesionGO:00071553290.053
cellular amine metabolic processGO:0044106440.053
small gtpase mediated signal transductionGO:0007264970.050
regulation of cellular amino acid metabolic processGO:000652150.050
regulation of cellular amine metabolic processGO:0033238200.048
regulation of cellular ketone metabolic processGO:0010565660.046
regulation of membrane potentialGO:00423911920.045
cellular ketone metabolic processGO:0042180840.042
cation transportGO:00068123990.042
urogenital system developmentGO:00016552610.038
nucleotide metabolic processGO:00091173320.037
ribose phosphate metabolic processGO:00196932910.037
heterocycle catabolic processGO:00467002800.037
nucleobase containing small molecule metabolic processGO:00550863520.037
positive regulation of protein modification processGO:00314012990.036
aromatic compound catabolic processGO:00194392860.036
microtubule based processGO:00070172360.035
positive regulation of cellular amino acid metabolic processGO:004576430.035
purine containing compound metabolic processGO:00725213110.034
cellular homeostasisGO:00197252400.033
stem cell differentiationGO:00488632680.032
renal system developmentGO:00720012250.031
regionalizationGO:00030023370.031
positive regulation of mapk cascadeGO:00434101700.031
oocyte constructionGO:000730820.031
respiratory tube developmentGO:00303231670.031
developmental growth involved in morphogenesisGO:00605601380.030
muscle cell differentiationGO:00426922610.030
developmental maturationGO:00217001930.030
gland developmentGO:00487323300.029
purine nucleotide metabolic processGO:00061633020.029
epidermis developmentGO:00085441870.029
respiratory system developmentGO:00605411900.029
organic cyclic compound catabolic processGO:19013612950.028
membrane organizationGO:00610242450.028
rho protein signal transductionGO:0007266320.028
regulation of cellular catabolic processGO:00313292420.028
positive regulation of cellular amine metabolic processGO:003324050.028
nucleoside phosphate metabolic processGO:00067533380.028
male gamete generationGO:00482322850.028
cellular nitrogen compound catabolic processGO:00442702800.028
regulation of kinase activityGO:00435492490.028
kidney developmentGO:00018222130.027
cellular lipid metabolic processGO:00442553230.027
positive regulation of neuron differentiationGO:00456661410.027
leukocyte differentiationGO:00025213420.027
Mouse
digestive system developmentGO:00551232000.027
regulation of cell cycleGO:00517262810.027
divalent inorganic cation transportGO:00725111780.026
regulation of protein kinase activityGO:00458592320.026
positive regulation of cell developmentGO:00107202370.026
nucleoside metabolic processGO:00091162460.026
negative regulation of cell proliferationGO:00082852960.026
ribonucleoside catabolic processGO:00424542060.026
purine ribonucleoside metabolic processGO:00461282410.025
regulation of cell projection organizationGO:00313442060.025
macromolecule catabolic processGO:00090572810.025
epithelial tube morphogenesisGO:00605623030.025
regulation of protein localizationGO:00328802310.025
apoptotic signaling pathwayGO:00971903060.025
synaptic transmissionGO:00072683290.025
positive regulation of protein phosphorylationGO:00019342420.024
negative regulation of nervous system developmentGO:00519611560.024
positive regulation of nervous system developmentGO:00519622210.024
regulation of lymphocyte activationGO:00512492400.024
ribonucleotide metabolic processGO:00092592910.023
oocyte axis specificationGO:000730920.023
cellular macromolecule catabolic processGO:00442652060.023
microtubule cytoskeleton organizationGO:00002261570.023
camera type eye developmentGO:00430102660.023
digestive tract developmentGO:00485651900.023
regulation of cell migrationGO:00303342190.023
striated muscle tissue developmentGO:00147062930.023
regulation of organelle organizationGO:00330432890.023
skin developmentGO:00435882200.023
purine ribonucleotide metabolic processGO:00091502900.023
tube formationGO:00351481400.023
regulation of protein serine threonine kinase activityGO:00719001570.022
g protein coupled receptor signaling pathwayGO:00071862430.022
forebrain developmentGO:00309003020.022
peptidyl amino acid modificationGO:00181933360.022
transmembrane transportGO:00550854120.022
dna metabolic processGO:00062593030.022
endomembrane system organizationGO:00102561470.022
ossificationGO:00015032160.022
oxidation reduction processGO:00551143420.021
cell fate commitmentGO:00451652100.021
adult behaviorGO:00305341350.021
purine ribonucleoside triphosphate catabolic processGO:00092071990.021
regulation of hydrolase activityGO:00513362460.021
purine nucleotide catabolic processGO:00061952110.021
regulation of cell activationGO:00508652890.021
axonogenesisGO:00074092740.021
regulation of cytoskeleton organizationGO:00514931220.021
negative regulation of cellular component organizationGO:00511291940.021
extracellular structure organizationGO:00430621480.021
regulation of purine nucleotide metabolic processGO:19005421690.021
lung developmentGO:00303241640.021
epithelial cell developmentGO:00020641590.020
stem cell developmentGO:00488642190.020
regulation of establishment of protein localizationGO:00702011810.020
regulation of nucleotide metabolic processGO:00061401690.020
guanosine containing compound metabolic processGO:19010681440.020
purine ribonucleotide catabolic processGO:00091542080.020
mitotic cell cycleGO:00002781950.020
nucleoside phosphate catabolic processGO:19012922220.020
protein localization to membraneGO:00726571080.020
morphogenesis of a branching structureGO:00017632030.020
morphogenesis of a branching epitheliumGO:00611381930.020
purine nucleoside triphosphate metabolic processGO:00091442260.020
purine nucleoside metabolic processGO:00422782410.020
purine nucleoside triphosphate catabolic processGO:00091462030.020
positive regulation of transferase activityGO:00513471670.020
kidney epithelium developmentGO:00720731210.020
regulation of neuron differentiationGO:00456642810.020
organophosphate catabolic processGO:00464342320.020
nucleoside catabolic processGO:00091642060.020
skeletal muscle organ developmentGO:00605381630.020
carbohydrate metabolic processGO:00059752300.020
regulation of organ morphogenesisGO:20000271440.019
sensory perceptionGO:00076002450.019
negative regulation of protein metabolic processGO:00512482820.019
leukocyte proliferationGO:00706611720.019
guanosine containing compound catabolic processGO:19010691440.019
cellular chemical homeostasisGO:00550822150.019
ribonucleoside triphosphate metabolic processGO:00091992200.019
purine ribonucleoside catabolic processGO:00461302050.019
chemotaxisGO:00069352470.019
anion transportGO:00068201770.019
positive regulation of apoptotic processGO:00430652170.019
organonitrogen compound catabolic processGO:19015652640.019
regulation of anatomical structure sizeGO:00900661780.019
spermatogenesisGO:00072832840.019
extrinsic apoptotic signaling pathwayGO:00971911260.019
morphogenesis of embryonic epitheliumGO:00163311590.019
blood circulationGO:00080151950.019
action potentialGO:0001508780.018
regulation of apoptotic signaling pathwayGO:20012331970.018
glycosyl compound catabolic processGO:19016582060.018
regulation of cellular response to stressGO:00801351590.018
gtp metabolic processGO:00460391440.018
response to organonitrogen compoundGO:00102432460.018
wnt signaling pathwayGO:00160551880.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.018
cytoplasmic transportGO:00164822340.018
compound eye developmentGO:004874910.018
regulation of ras protein signal transductionGO:00465781140.018
nephron developmentGO:00720061090.018
ribonucleoside metabolic processGO:00091192450.018
organelle fissionGO:00482851700.018
negative regulation of molecular functionGO:00440922580.018
branching morphogenesis of an epithelial tubeGO:00487541590.018
response to extracellular stimulusGO:00099911270.018
regulation of hormone levelsGO:00108172110.017
carbohydrate derivative catabolic processGO:19011362310.017
transmission of nerve impulseGO:0019226760.017
regulation of response to woundingGO:19030341890.017
regulation of transcription from rna polymerase iii promoterGO:000635920.017
multicellular organismal homeostasisGO:00488711640.017
skeletal system developmentGO:00015013560.017
extracellular matrix organizationGO:00301981470.017
mitotic cell cycle processGO:19030471590.017
negative regulation of cell developmentGO:00107211690.017
immune effector processGO:00022523210.017
regulation of cell adhesionGO:00301551540.017
embryonic organ morphogenesisGO:00485622760.017
inorganic cation transmembrane transportGO:00986622070.017
stem cell proliferationGO:00720891170.017
epithelial cell proliferationGO:00506731740.017
muscle tissue developmentGO:00605373080.017
cation transmembrane transportGO:00986552660.017
regulation of cell motilityGO:20001452360.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.017
nucleotide catabolic processGO:00091662170.017
cytokine productionGO:00018163190.017
positive regulation of kinase activityGO:00336741550.016
myeloid leukocyte differentiationGO:00025731190.016
organonitrogen compound biosynthetic processGO:19015661920.016
regulation of secretionGO:00510462740.016
glycosyl compound metabolic processGO:19016572460.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.016
negative regulation of phosphorylationGO:00423261660.016
positive regulation of cell activationGO:00508671580.016
nitrogen compound transportGO:00717052710.016
cellular response to organonitrogen compoundGO:00714171450.016
protein maturationGO:00516041760.016
inorganic ion transmembrane transportGO:00986602340.016
gtp catabolic processGO:00061841430.016
pole plasm assemblyGO:000731520.016
response to organic cyclic compoundGO:00140701980.016
nephrogenic mesenchyme developmentGO:007207630.016
placenta developmentGO:00018901400.016
germ cell developmentGO:00072811850.016
nuclear divisionGO:00002801580.016
regulation of secretion by cellGO:19035302490.016
oocyte anterior posterior axis specificationGO:000731420.016
purine ribonucleoside triphosphate metabolic processGO:00092052200.016
intracellular protein transportGO:00068862040.016
cell maturationGO:00484691270.016
muscle system processGO:00030121410.016
positive regulation of protein kinase activityGO:00458601440.016
intracellular mrna localizationGO:000829840.016
negative regulation of cell cycleGO:00457861230.015
nucleoside triphosphate metabolic processGO:00091412300.015
anatomical structure homeostasisGO:00602491450.015
positive regulation of cellular catabolic processGO:00313311480.015
skeletal system morphogenesisGO:00487052030.015
metanephros developmentGO:0001656790.015
angiogenesisGO:00015252010.015
sequestering of metal ionGO:0051238190.015
regulation of synaptic growth at neuromuscular junctionGO:000858240.015
regulation of interleukin 8 productionGO:003267730.015
multicellular organism growthGO:00352641610.015
circulatory system processGO:00030131970.015
bone developmentGO:00603481200.015
response to growth factorGO:00708481980.015
organic hydroxy compound metabolic processGO:19016152030.015
carbohydrate homeostasisGO:00335001280.015
lateral inhibitionGO:004633110.015
cell substrate adhesionGO:00315891300.015
cell type specific apoptotic processGO:00972852680.015
canonical wnt signaling pathwayGO:00600701300.015
regulation of gtp catabolic processGO:00331241130.015
single organismal cell cell adhesionGO:00163371310.015
ameboidal type cell migrationGO:00016671280.015
regulation of cytokine productionGO:00018172660.015
negative regulation of apoptotic signaling pathwayGO:20012341040.015
organelle localizationGO:00516401790.015
embryonic placenta developmentGO:0001892980.015
posttranscriptional regulation of gene expressionGO:00106081550.014
negative regulation of phosphate metabolic processGO:00459361840.014
meiotic cell cycleGO:00513211220.014
t cell activationGO:00421102890.014
phospholipid metabolic processGO:0006644870.014
purine nucleoside catabolic processGO:00061522050.014
regulation of homeostatic processGO:00328441820.014
sensory organ morphogenesisGO:00905962420.014
maintenance of locationGO:0051235890.014
nephron epithelium developmentGO:0072009920.014
nucleoside triphosphate catabolic processGO:00091432050.014
single organism cell adhesionGO:00986021560.014
regulation of wnt signaling pathwayGO:00301111230.014
calcium ion transportGO:00068161590.014
t cell proliferationGO:00420981200.014
regulation of system processGO:00440572000.014
blastocyst developmentGO:0001824800.014
reactive oxygen species metabolic processGO:0072593840.014
endocytosisGO:00068971680.014
response to nutrient levelsGO:00316671090.014
telencephalon developmentGO:00215371860.014
digestive tract morphogenesisGO:00485461470.014
pharynx developmentGO:006046510.014
fat cell differentiationGO:00454441600.014
Mouse
divalent metal ion transportGO:00708381720.014
regulation of map kinase activityGO:00434051200.013
actin cytoskeleton organizationGO:00300362200.013
cellular response to hormone stimulusGO:00328701500.013
inflammatory responseGO:00069542440.013
maternal determination of anterior posterior axis embryoGO:000835820.013
cell activation involved in immune responseGO:00022631260.013
protein localization to organelleGO:00333651850.013
regulation of epithelial cell proliferationGO:00506781410.013
amide transportGO:00428861380.013
positive regulation of protein serine threonine kinase activityGO:00719021060.013
response to lipopolysaccharideGO:00324961280.013
organic anion transportGO:00157111370.013
epithelial tube formationGO:00721751300.013
protein ubiquitinationGO:00165671710.013
regulation of cellular component biogenesisGO:00440871810.013
sequestering of calcium ionGO:0051208180.013
cell growthGO:00160491300.013
negative regulation of organelle organizationGO:0010639900.013
cellular response to lipidGO:00713961450.013
retina development in camera type eyeGO:00600411190.013
purine containing compound catabolic processGO:00725232130.013
regulation of body fluid levelsGO:00508781620.013
carbohydrate derivative biosynthetic processGO:19011371830.013
regulation of protein transportGO:00512231630.013
alcohol metabolic processGO:00060661160.013
innate immune responseGO:00450871570.013
lipid transportGO:0006869980.013
actin filament organizationGO:00070151130.013
positive regulation of apoptotic signaling pathwayGO:2001235950.013
positive regulation of immature t cell proliferationGO:003309140.013
ribonucleotide catabolic processGO:00092612080.013
transcription from rna polymerase iii promoterGO:000638330.013
cellular response to growth factor stimulusGO:00713631970.013
synapse organizationGO:00508081250.013
neural precursor cell proliferationGO:00613511210.013
lateral line system developmentGO:004892510.013
regulation of t cell activationGO:00508631700.013
tissue remodelingGO:00487711020.013
rna interferenceGO:001624620.013
blood vessel morphogenesisGO:00485142850.012
meiotic nuclear divisionGO:00071261150.012
regulation of nucleoside metabolic processGO:00091181300.012
appendage developmentGO:00487361660.012
positive regulation of programmed cell deathGO:00430682180.012
negative regulation of transferase activityGO:0051348850.012
cellular ion homeostasisGO:00068731650.012
axon guidanceGO:00074111410.012
regulation of embryonic developmentGO:0045995710.012
multicellular organismal signalingGO:0035637910.012
regulation of defense responseGO:00313472330.012
neuronal action potentialGO:0019228540.012
cellular protein complex assemblyGO:00436231160.012
kidney morphogenesisGO:0060993830.012
sensory system developmentGO:004888030.012
protein catabolic processGO:00301632210.012
metal ion homeostasisGO:00550651890.012
ear developmentGO:00435832000.012
positive regulation of nucleotide metabolic processGO:00459811140.012
regulation of cell cycle processGO:00105641600.012
fertilizationGO:00095661270.012
positive regulation of lymphocyte activationGO:00512511400.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
organ growthGO:00352651170.012
protein targetingGO:00066051430.012
appendage morphogenesisGO:00351071490.012
regulation of nucleotide catabolic processGO:00308111220.012
gonad developmentGO:00084061410.012
pattern specification involved in metanephros developmentGO:007226840.012
regulation of vascular wound healingGO:006104320.012
lymphocyte proliferationGO:00466511640.012
cation homeostasisGO:00550802120.012
mesonephric tubule developmentGO:0072164940.012
plasma membrane organizationGO:0007009900.012
positive regulation of hydrolase activityGO:00513451480.012
neuron projection guidanceGO:00974851410.012
positive regulation of protein transportGO:0051222930.012
homeostasis of number of cellsGO:00488722100.012
lipid biosynthetic processGO:00086101790.012
formation of organ boundaryGO:001016010.012
mesangial cell differentiationGO:007200740.012
smoothened signaling pathwayGO:00072241050.011
negative regulation of cellular amino acid metabolic processGO:004576300.011
steroid metabolic processGO:00082021190.011
positive regulation of growthGO:00459271040.011
neural tube formationGO:00018411080.011
rhythmic processGO:00485111740.011
heart morphogenesisGO:00030071780.011
cellular metal ion homeostasisGO:00068751510.011
regulation of neural precursor cell proliferationGO:2000177700.011
mesonephros developmentGO:0001823970.011
regulation of ion transportGO:00432692150.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.011
glucose metabolic processGO:0006006920.011
regulation of neuron projection developmentGO:00109751690.011
monocarboxylic acid metabolic processGO:00327871910.011
single fertilizationGO:0007338820.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
negative regulation of cellular amine metabolic processGO:003323910.011
positive regulation of cell adhesionGO:0045785800.011
regulation of microtubule based processGO:0032886520.011
mesodermal cell migrationGO:000807840.011
carbon catabolite activation of transcriptionGO:004599140.011
female sex determinationGO:003023710.011
protein modification by small protein conjugation or removalGO:00706472070.011
positive regulation of cell projection organizationGO:0031346950.011
regulation of intracellular transportGO:00323861590.011
positive regulation of gtpase activityGO:0043547850.011
regulation of muscle tissue developmentGO:1901861970.011
female sex differentiationGO:0046660840.011
development of primary sexual characteristicsGO:00451371430.011
peptidyl serine modificationGO:0018209830.011
nephron epithelium morphogenesisGO:0072088680.011
regulation of ras gtpase activityGO:0032318880.011
segmentationGO:0035282930.011
cell divisionGO:00513011200.011
muscle cell developmentGO:00550011330.011
interleukin 8 productionGO:003263740.011
regulation of lipid metabolic processGO:00192161180.011
negative regulation of neuron differentiationGO:00456651010.011
regulation of purine nucleotide catabolic processGO:00331211220.011
stress activated protein kinase signaling cascadeGO:0031098810.011
positive regulation of cell deathGO:00109422240.011
stress activated mapk cascadeGO:0051403800.011
exocytosisGO:00068871210.011
positive regulation of t cell activationGO:00508701010.011
myeloid cell differentiationGO:00300992330.011
establishment or maintenance of cell polarityGO:0007163860.010
meiotic cell cycle processGO:1903046770.010
regulation of cell substrate adhesionGO:0010810730.010
cellular protein catabolic processGO:00442571550.010
midgut developmentGO:000749440.010
wound healingGO:00420601570.010
positive regulation of ras gtpase activityGO:0032320650.010
adult locomotory behaviorGO:0008344910.010
cell junction assemblyGO:0034329520.010
positive regulation of gtp catabolic processGO:0033126850.010
hindbrain developmentGO:00309021280.010
gastrulationGO:00073691160.010
neural tube developmentGO:00219151600.010
lung morphogenesisGO:0060425500.010
regulation of leukocyte differentiationGO:19021051590.010
locomotory behaviorGO:00076261950.010
cell killingGO:0001906670.010
reactive nitrogen species metabolic processGO:200105700.010
positive regulation of defense responseGO:00313491240.010
positive regulation of ion transportGO:0043270650.010
glycoprotein metabolic processGO:00091001160.010
ureteric bud developmentGO:0001657940.010
regulation of erk1 and erk2 cascadeGO:0070372710.010
negative regulation of cellular protein metabolic processGO:00322692470.010
peptide hormone secretionGO:00300721090.010
lipid homeostasisGO:0055088630.010
positive regulation of cell cycleGO:0045787920.010
stem cell maintenanceGO:00198271300.010
negative regulation of kinase activityGO:0033673810.010
ion transmembrane transportGO:00342203610.010
interleukin 8 secretionGO:007260630.010
connective tissue developmentGO:00614481790.010
peptidyl serine phosphorylationGO:0018105740.010
mesonephric epithelium developmentGO:0072163940.010
leukocyte mediated immunityGO:00024431740.010
cellular response to biotic stimulusGO:0071216920.010

Lrrc8e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.013
nervous system diseaseDOID:86300.013
sensory system diseaseDOID:005015500.013
disease of cellular proliferationDOID:1456600.012
disease of metabolismDOID:001466700.012
organ system cancerDOID:005068600.011
cancerDOID:16200.011