Mus musculus

21 known processes

Prlhr

prolactin releasing hormone receptor

(Aliases: Gm339,Prrpr,Gr3,Gpr10)

Prlhr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cation transmembrane transportGO:00986552660.131
reactive nitrogen species metabolic processGO:200105700.115
negative regulation of camp mediated signalingGO:004395130.115
reactive oxygen species metabolic processGO:0072593840.108
ion transmembrane transportGO:00342203610.108
regulation of cellular amine metabolic processGO:0033238200.105
neuropeptide signaling pathwayGO:0007218190.101
Mouse
transmembrane transportGO:00550854120.099
reactive oxygen species biosynthetic processGO:190340980.097
regulation of reactive oxygen species metabolic processGO:2000377400.097
amine metabolic processGO:0009308450.096
positive regulation of cellular amine metabolic processGO:003324050.093
cellular ketone metabolic processGO:0042180840.089
regulation of saliva secretionGO:004687720.089
sensory perceptionGO:00076002450.087
Mouse
purine containing compound metabolic processGO:00725213110.085
negative regulation of cell migrationGO:0030336590.084
inorganic cation transmembrane transportGO:00986622070.082
nucleobase containing small molecule metabolic processGO:00550863520.081
glucose homeostasisGO:00425931280.081
nucleotide metabolic processGO:00091173320.080
inorganic ion transmembrane transportGO:00986602340.078
regulation of reactive oxygen species biosynthetic processGO:190342620.076
positive regulation of nervous system developmentGO:00519622210.076
nucleoside phosphate metabolic processGO:00067533380.075
positive regulation of reactive oxygen species biosynthetic processGO:190342820.073
synaptic transmissionGO:00072683290.072
Mouse
positive regulation of cell developmentGO:00107202370.070
purine nucleotide metabolic processGO:00061633020.068
negative regulation of purine nucleotide metabolic processGO:1900543160.068
negative regulation of molecular functionGO:00440922580.067
cation transportGO:00068123990.063
purine ribonucleotide metabolic processGO:00091502900.063
regulation of membrane potentialGO:00423911920.062
nucleoside phosphate biosynthetic processGO:1901293790.062
cellular amine metabolic processGO:0044106440.061
g protein coupled receptor signaling pathwayGO:00071862430.060
organophosphate biosynthetic processGO:00904071220.060
regulation of cyclic nucleotide metabolic processGO:0030799400.059
camp metabolic processGO:0046058400.058
positive regulation of protein modification processGO:00314012990.057
purine containing compound biosynthetic processGO:0072522700.056
negative regulation of phosphate metabolic processGO:00459361840.056
carbohydrate derivative biosynthetic processGO:19011371830.056
ribose phosphate metabolic processGO:00196932910.055
carbohydrate homeostasisGO:00335001280.054
purine nucleotide biosynthetic processGO:0006164650.054
cellular response to organonitrogen compoundGO:00714171450.053
cyclic nucleotide metabolic processGO:0009187590.053
negative regulation of cell motilityGO:2000146610.052
response to organonitrogen compoundGO:00102432460.052
opioid receptor signaling pathwayGO:003800350.051
negative regulation of cell proliferationGO:00082852960.051
response to lipopolysaccharideGO:00324961280.051
regulation of cell cycleGO:00517262810.050
male gamete generationGO:00482322850.050
cellular amino acid metabolic processGO:00065201030.049
negative regulation of lyase activityGO:005135010.049
negative regulation of nucleotide metabolic processGO:0045980160.048
positive regulation of mapk cascadeGO:00434101700.048
nucleotide biosynthetic processGO:0009165780.048
mapk cascadeGO:00001652810.048
positive regulation of reactive oxygen species metabolic processGO:2000379110.048
regulation of cellular amino acid metabolic processGO:000652150.048
angiogenesisGO:00015252010.047
cellular calcium ion homeostasisGO:00068741190.046
ribonucleotide metabolic processGO:00092592910.046
regulation of nucleotide metabolic processGO:00061401690.044
nitrogen compound transportGO:00717052710.044
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.044
Mouse
negative regulation of intracellular signal transductionGO:19025321670.044
regulation of cellular ketone metabolic processGO:0010565660.042
response to growth factorGO:00708481980.042
positive regulation of cellular amino acid metabolic processGO:004576430.042
cellular lipid metabolic processGO:00442553230.042
regulation of camp biosynthetic processGO:0030817250.042
ribonucleotide biosynthetic processGO:0009260590.041
ribose phosphate biosynthetic processGO:0046390590.041
wound healingGO:00420601570.040
regulation of ion transmembrane transportGO:00347651190.040
organonitrogen compound biosynthetic processGO:19015661920.040
regulation of body fluid levelsGO:00508781620.040
cyclic purine nucleotide metabolic processGO:0052652430.039
regulation of purine nucleotide metabolic processGO:19005421690.039
calcium ion transmembrane transportGO:0070588850.038
positive regulation of camp mediated signalingGO:004395030.038
macromolecule catabolic processGO:00090572810.038
dopamine receptor signaling pathwayGO:0007212160.038
cyclic nucleotide biosynthetic processGO:0009190440.038
regulation of ion transportGO:00432692150.038
positive regulation of protein phosphorylationGO:00019342420.038
regulation of transmembrane transportGO:00347621280.038
spermatogenesisGO:00072832840.037
regulation of nucleotide biosynthetic processGO:0030808340.037
locomotory behaviorGO:00076261950.036
Mouse
regulation of cell migrationGO:00303342190.036
regulation of protein localizationGO:00328802310.035
regulation of camp metabolic processGO:0030814300.034
regulation of kinase activityGO:00435492490.034
divalent inorganic cation homeostasisGO:00725071380.034
regulation of protein kinase activityGO:00458592320.033
calcium ion homeostasisGO:00550741270.033
oxidation reduction processGO:00551143420.033
regulation of cell motilityGO:20001452360.033
glutamate receptor signaling pathwayGO:0007215350.033
inflammatory responseGO:00069542440.033
immune effector processGO:00022523210.033
cellular nitrogen compound catabolic processGO:00442702800.033
regulation of protein transportGO:00512231630.033
response to molecule of bacterial originGO:00022371430.032
regulation of cyclic nucleotide biosynthetic processGO:0030802310.032
regulation of cell activationGO:00508652890.032
cellular response to ammonium ionGO:007124220.032
regulation of mapk cascadeGO:00434082480.032
divalent inorganic cation transportGO:00725111780.032
cellular ion homeostasisGO:00068731650.032
peptide transportGO:00158331330.031
regulation of purine nucleotide biosynthetic processGO:1900371340.031
organic cyclic compound catabolic processGO:19013612950.031
blood vessel morphogenesisGO:00485142850.031
negative regulation of cyclase activityGO:003128010.030
cation homeostasisGO:00550802120.030
regulation of secretionGO:00510462740.030
purine ribonucleotide biosynthetic processGO:0009152590.030
negative regulation of adenylate cyclase activityGO:000719410.030
cellular chemical homeostasisGO:00550822150.030
regulation of feeding behaviorGO:006025930.029
negative regulation of phosphorus metabolic processGO:00105631840.029
regulation of establishment of protein localizationGO:00702011810.029
cellular macromolecule catabolic processGO:00442652060.029
adenylate cyclase activating g protein coupled receptor signaling pathwayGO:0007189300.029
response to organic cyclic compoundGO:00140701980.029
Mouse
regulation of hormone levelsGO:00108172110.029
negative regulation of immune system processGO:00026832090.029
peptide secretionGO:00027901140.029
positive regulation of erk1 and erk2 cascadeGO:0070374470.029
regulation of secretion by cellGO:19035302490.028
cellular response to hormone stimulusGO:00328701500.028
cellular divalent inorganic cation homeostasisGO:00725031270.028
regulation of mitotic cell cycleGO:00073461260.028
blood circulationGO:00080151950.027
Mouse
hormone secretionGO:00468791280.027
peptide hormone secretionGO:00300721090.026
adult behaviorGO:00305341350.026
gland developmentGO:00487323300.026
Mouse
developmental maturationGO:00217001930.026
heterocycle catabolic processGO:00467002800.026
muscle tissue developmentGO:00605373080.026
protein catabolic processGO:00301632210.025
regulation of cell projection organizationGO:00313442060.025
regulation of cell cycle processGO:00105641600.025
camp biosynthetic processGO:0006171310.025
regulation of erk1 and erk2 cascadeGO:0070372710.024
cellular metal ion homeostasisGO:00068751510.024
negative regulation of protein metabolic processGO:00512482820.024
regulation of hydrolase activityGO:00513362460.024
defense response to other organismGO:00985421970.024
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.024
Mouse
metal ion homeostasisGO:00550651890.024
regulation of defense responseGO:00313472330.024
cell adhesionGO:00071553290.024
erk1 and erk2 cascadeGO:0070371770.024
divalent metal ion transportGO:00708381720.024
positive regulation of cell deathGO:00109422240.024
regulation of peptide secretionGO:0002791770.024
stem cell developmentGO:00488642190.024
amide transportGO:00428861380.023
negative regulation of cyclic nucleotide metabolic processGO:003080050.023
sensory organ morphogenesisGO:00905962420.023
lipid biosynthetic processGO:00086101790.023
camera type eye developmentGO:00430102660.023
protein secretionGO:00093061110.023
cell fate commitmentGO:00451652100.023
cellular homeostasisGO:00197252400.023
regulation of peptide hormone secretionGO:0090276750.023
circulatory system processGO:00030131970.023
Mouse
cytoplasmic transportGO:00164822340.022
morphogenesis of a branching structureGO:00017632030.022
b cell activationGO:00421131610.022
regulation of neuron projection developmentGO:00109751690.022
striated muscle tissue developmentGO:00147062930.022
negative regulation of purine nucleotide biosynthetic processGO:190037260.022
multicellular organism growthGO:00352641610.022
Mouse
regulation of hormone secretionGO:0046883880.021
positive regulation of secretion by cellGO:19035321140.021
regulation of neuron differentiationGO:00456642810.021
insulin secretionGO:0030073890.021
lymphocyte differentiationGO:00300982420.021
regulation of system processGO:00440572000.021
regulation of organelle organizationGO:00330432890.021
skeletal muscle organ developmentGO:00605381630.020
axonogenesisGO:00074092740.020
Mouse
cytokine productionGO:00018163190.020
aromatic compound catabolic processGO:00194392860.020
leukocyte differentiationGO:00025213420.020
stem cell differentiationGO:00488632680.020
response to foodGO:0032094170.020
posttranscriptional regulation of gene expressionGO:00106081550.020
peptidyl amino acid modificationGO:00181933360.020
regulation of anatomical structure sizeGO:00900661780.020
regulation of transporter activityGO:0032409570.019
regulation of ion transmembrane transporter activityGO:0032412540.019
response to extracellular stimulusGO:00099911270.019
cell maturationGO:00484691270.019
organic hydroxy compound metabolic processGO:19016152030.019
organic hydroxy compound transportGO:0015850930.019
cellular response to organic cyclic compoundGO:0071407870.019
potassium ion transportGO:0006813520.019
positive regulation of cytosolic calcium ion concentrationGO:0007204650.019
positive regulation of programmed cell deathGO:00430682180.019
protein processingGO:00164851630.019
negative regulation of cell developmentGO:00107211690.019
protein maturationGO:00516041760.019
organic anion transportGO:00157111370.019
neuron migrationGO:00017641220.019
Mouse
muscle system processGO:00030121410.018
heart processGO:0003015940.018
regulation of cyclase activityGO:0031279130.018
lymphocyte activation involved in immune responseGO:0002285930.018
cell activation involved in immune responseGO:00022631260.018
negative regulation of cellular protein metabolic processGO:00322692470.018
regulation of transferase activityGO:00513382630.018
skeletal system developmentGO:00015013560.018
regulation of circadian sleep wake cycleGO:004274930.018
small gtpase mediated signal transductionGO:0007264970.018
cellular response to molecule of bacterial originGO:0071219830.018
regulation of excitatory postsynaptic membrane potentialGO:0060079410.018
lymphocyte proliferationGO:00466511640.017
regulation of cytokine productionGO:00018172660.017
response to oxidative stressGO:00069791230.017
adaptive immune responseGO:00022501550.017
modification dependent protein catabolic processGO:00199411330.017
second messenger mediated signalingGO:0019932730.017
cytosolic calcium ion homeostasisGO:0051480700.017
body fluid secretionGO:0007589530.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.017
response to radiationGO:00093141650.017
cellular response to dna damage stimulusGO:00069742070.017
regulation of action potentialGO:009890040.017
microtubule based processGO:00070172360.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.017
lung developmentGO:00303241640.017
regulation of homeostatic processGO:00328441820.017
nitric oxide biosynthetic processGO:0006809250.017
regulation of protein processingGO:0070613960.017
sequestering of metal ionGO:0051238190.017
protein ubiquitinationGO:00165671710.017
cell divisionGO:00513011200.016
tissue remodelingGO:00487711020.016
myotube differentiationGO:00149021050.016
positive regulation of growthGO:00459271040.016
nitric oxide metabolic processGO:0046209250.016
regulation of camp mediated signalingGO:004394970.016
negative regulation of protein transportGO:0051224460.016
positive regulation of apoptotic processGO:00430652170.016
germ cell developmentGO:00072811850.016
response to nutrient levelsGO:00316671090.016
response to inorganic substanceGO:0010035960.016
regulation of lyase activityGO:0051339130.016
rhythmic processGO:00485111740.016
Mouse
pigmentationGO:0043473710.016
negative regulation of cellular amine metabolic processGO:003323910.015
spermatid differentiationGO:00485151150.015
negative regulation of phosphorylationGO:00423261660.015
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200260.015
Mouse
mitotic cell cycleGO:00002781950.015
dna metabolic processGO:00062593030.015
regulation of lymphocyte activationGO:00512492400.015
kidney developmentGO:00018222130.015
mitotic cell cycle processGO:19030471590.015
anion transportGO:00068201770.015
positive regulation of secretionGO:00510471300.015
calcium ion transportGO:00068161590.015
maintenance of locationGO:0051235890.015
leukocyte mediated immunityGO:00024431740.015
regulation of g protein coupled receptor protein signaling pathwayGO:0008277370.015
regulation of proteolysisGO:00301621640.015
organelle fissionGO:00482851700.015
positive regulation of cytokine productionGO:00018191740.015
response to light stimulusGO:00094161350.015
smoothened signaling pathwayGO:00072241050.015
wnt signaling pathwayGO:00160551880.015
proteolysis involved in cellular protein catabolic processGO:00516031470.015
respiratory system developmentGO:00605411900.015
response to acid chemicalGO:00011011110.015
skin developmentGO:00435882200.015
lipid transportGO:0006869980.014
intracellular protein transportGO:00068862040.014
negative regulation of protein modification processGO:00314001630.014
positive regulation of neuron differentiationGO:00456661410.014
negative regulation of transferase activityGO:0051348850.014
meiotic nuclear divisionGO:00071261150.014
response to alkaloidGO:0043279340.014
leukocyte proliferationGO:00706611720.014
regulation of response to woundingGO:19030341890.014
cellular protein catabolic processGO:00442571550.014
positive regulation of immune effector processGO:00026991070.014
sensory perception of painGO:0019233470.014
Mouse
sensory perception of mechanical stimulusGO:00509541070.014
actin cytoskeleton organizationGO:00300362200.014
adult locomotory behaviorGO:0008344910.014
developmental growth involved in morphogenesisGO:00605601380.014
ras protein signal transductionGO:0007265770.014
inflammatory response to antigenic stimulusGO:0002437300.014
somatostatin signaling pathwayGO:003817020.014
regulation of receptor activityGO:0010469410.014
rho protein signal transductionGO:0007266320.014
protein modification by small protein conjugation or removalGO:00706472070.014
lymphocyte mediated immunityGO:00024491390.014
forebrain developmentGO:00309003020.014
Mouse
chromatin organizationGO:00063252060.014
positive regulation of cell projection organizationGO:0031346950.014
endocytosisGO:00068971680.014
organelle localizationGO:00516401790.014
lateral inhibitionGO:004633110.013
regionalizationGO:00030023370.013
glycerolipid metabolic processGO:00464861220.013
nucleotide catabolic processGO:00091662170.013
defense response to bacteriumGO:00427421190.013
response to oxygen levelsGO:0070482620.013
regulation of apoptotic signaling pathwayGO:20012331970.013
cellular response to growth factor stimulusGO:00713631970.013
heart contractionGO:0060047930.013
adenylate cyclase activating dopamine receptor signaling pathwayGO:000719170.013
positive regulation of defense responseGO:00313491240.013
regulation of bindingGO:00510981110.013
mrna metabolic processGO:0016071840.013
regulation of postsynaptic membrane potentialGO:0060078480.013
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathwayGO:005148240.013
regulation of circadian sleep wake cycle sleepGO:004518730.013
negative regulation of secretionGO:0051048610.013
t cell activationGO:00421102890.013
negative regulation of cell cycleGO:00457861230.013
compound eye developmentGO:004874910.013
potassium ion transmembrane transportGO:0071805430.013
action potentialGO:0001508780.013
cellular response to oxidative stressGO:0034599760.013
modification dependent macromolecule catabolic processGO:00436321330.013
regulation of muscle system processGO:0090257800.013
ameboidal type cell migrationGO:00016671280.013
negative regulation of cytosolic calcium ion concentrationGO:005148120.013
negative regulation of nervous system developmentGO:00519611560.013
purine nucleoside triphosphate metabolic processGO:00091442260.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
innate immune responseGO:00450871570.012
negative regulation of cyclic nucleotide biosynthetic processGO:003080350.012
protein localization to organelleGO:00333651850.012
negative regulation of secretion by cellGO:1903531540.012
regulation of nitric oxide biosynthetic processGO:0045428180.012
fatty acid metabolic processGO:00066311210.012
purine ribonucleoside metabolic processGO:00461282410.012
membrane depolarizationGO:0051899640.012
cellular response to biotic stimulusGO:0071216920.012
respiratory tube developmentGO:00303231670.012
fat cell differentiationGO:00454441600.012
rna processingGO:00063961050.012
engulfment of apoptotic cellGO:004365230.012
regulation of smoothened signaling pathwayGO:0008589580.012
organ growthGO:00352651170.012
apoptotic signaling pathwayGO:00971903060.012
sperm motilityGO:0030317470.012
mesenchyme developmentGO:00604851520.012
sequestering of calcium ionGO:0051208180.012
leukocyte activation involved in immune responseGO:00023661260.012
ossificationGO:00015032160.012
extracellular matrix organizationGO:00301981470.012
regulation of lymphocyte differentiationGO:00456191070.012
nuclear divisionGO:00002801580.012
regulation of blood pressureGO:0008217930.012
Mouse
tissue homeostasisGO:00018941150.012
negative regulation of hydrolase activityGO:0051346710.012
protein modification by small protein conjugationGO:00324461870.012
covalent chromatin modificationGO:00165691630.012
negative regulation of cell activationGO:00508661110.012
ubiquitin dependent protein catabolic processGO:00065111290.012
negative regulation of protein secretionGO:0050709200.012
branching morphogenesis of an epithelial tubeGO:00487541590.012
cell type specific apoptotic processGO:00972852680.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
t cell differentiationGO:00302171740.012
microtubule cytoskeleton organizationGO:00002261570.012
multicellular organismal homeostasisGO:00488711640.012
ear developmentGO:00435832000.012
sensory perception of chemical stimulusGO:0007606510.012
regulation of cell adhesionGO:00301551540.012
meiotic cell cycleGO:00513211220.012
small molecule biosynthetic processGO:00442831320.012
detection of stimulusGO:0051606840.012
muscle cell differentiationGO:00426922610.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
regulation of synaptic transmission gabaergicGO:0032228170.011
spermatid developmentGO:00072861080.011
homeostasis of number of cellsGO:00488722100.011
nucleoside phosphate catabolic processGO:19012922220.011
activation of immune responseGO:00022531380.011
regulation of cell morphogenesis involved in differentiationGO:00107691510.011
regulation of cellular response to stressGO:00801351590.011
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.011
alcohol metabolic processGO:00060661160.011
chromatin modificationGO:00165681870.011
cofactor metabolic processGO:0051186800.011
peptidyl tyrosine modificationGO:00182121450.011
embryonic organ morphogenesisGO:00485622760.011
positive regulation of nucleotide metabolic processGO:00459811140.011
cell substrate adhesionGO:00315891300.011
stem cell maintenanceGO:00198271300.011
regulation of protein serine threonine kinase activityGO:00719001570.011
negative regulation of t cell activationGO:0050868650.011
regulation of multi organism processGO:00439001110.011
cellular response to amino acid stimulusGO:0071230290.011
single organism cell adhesionGO:00986021560.011
regulation of leukocyte proliferationGO:00706631210.011
proteasomal protein catabolic processGO:0010498980.011
immune response regulating signaling pathwayGO:00027641250.011
cellular response to lipidGO:00713961450.011
protein importGO:00170381010.011
cellular response to lipopolysaccharideGO:0071222770.011
carbohydrate metabolic processGO:00059752300.011
Mouse
saliva secretionGO:004654160.011
nuclear transportGO:00511691390.011
regulation of neural precursor cell proliferationGO:2000177700.011
negative regulation of reactive oxygen species biosynthetic processGO:190342700.011
epithelial tube morphogenesisGO:00605623030.011
histone modificationGO:00165701590.011
hindbrain developmentGO:00309021280.011
nucleoside catabolic processGO:00091642060.011
regulation of cellular catabolic processGO:00313292420.011
cell growthGO:00160491300.011
digestionGO:0007586400.011
Mouse
leukocyte migrationGO:00509001240.011
transmission of nerve impulseGO:0019226760.011
anatomical structure homeostasisGO:00602491450.011
regulation of metal ion transportGO:00109591060.011
regulation of b cell activationGO:0050864810.011
negative regulation of protein phosphorylationGO:00019331260.011
regulation of adaptive immune responseGO:0002819900.011
protein targetingGO:00066051430.011
interspecies interaction between organismsGO:0044419830.011
response to steroid hormoneGO:0048545560.011
Mouse
nucleoside metabolic processGO:00091162460.011
ribonucleoside metabolic processGO:00091192450.011
pharynx developmentGO:006046510.011
positive regulation of cellular catabolic processGO:00313311480.010
renal system developmentGO:00720012250.010
negative regulation of mapk cascadeGO:0043409650.010
negative regulation of multi organism processGO:0043901680.010
connective tissue developmentGO:00614481790.010
positive regulation of neuron projection developmentGO:0010976790.010
multicellular organismal signalingGO:0035637910.010
cognitionGO:00508901490.010
b cell differentiationGO:0030183780.010
digestive system developmentGO:00551232000.010
Mouse
glycosyl compound metabolic processGO:19016572460.010
positive regulation of transferase activityGO:00513471670.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
nucleocytoplasmic transportGO:00069131390.010
positive regulation of organelle organizationGO:00106381280.010
hormone mediated signaling pathwayGO:0009755230.010
epithelial cell developmentGO:00020641590.010
defense response to virusGO:0051607680.010
regulation of adenylate cyclase activityGO:0045761100.010
purine nucleoside triphosphate catabolic processGO:00091462030.010
telencephalon developmentGO:00215371860.010
positive regulation of cell cycle processGO:0090068610.010
glycoprotein metabolic processGO:00091001160.010
regulation of translationGO:0006417710.010
camp mediated signalingGO:0019933150.010

Prlhr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
nervous system diseaseDOID:86300.030
central nervous system diseaseDOID:33100.018
disease of metabolismDOID:001466700.017
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
sensory system diseaseDOID:005015500.014
organ system cancerDOID:005068600.014
musculoskeletal system diseaseDOID:1700.013
acquired metabolic diseaseDOID:006015800.011
neurodegenerative diseaseDOID:128900.010