Mus musculus

41 known processes

Mid1

midline 1

(Aliases: MGC60591,DXHXS1141,Fxy,61B3-R,Trim18)

Mid1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
fertilizationGO:00095661270.182
negative regulation of fibroblast migrationGO:001076420.176
negative regulation of synaptic vesicle transportGO:190280430.135
cellular amino acid metabolic processGO:00065201030.134
regulation of cellular ketone metabolic processGO:0010565660.126
positive regulation of mapk cascadeGO:00434101700.126
Human
membrane organizationGO:00610242450.125
regulation of response to drugGO:200102320.109
positive regulation of neuron differentiationGO:00456661410.106
regulation of cellular amine metabolic processGO:0033238200.102
cell fate commitmentGO:00451652100.098
response to organonitrogen compoundGO:00102432460.098
spermatogenesisGO:00072832840.088
striated muscle tissue developmentGO:00147062930.086
regulation of synaptic vesicle exocytosisGO:2000300110.085
regulation of cell motilityGO:20001452360.085
positive regulation of cell developmentGO:00107202370.083
neuron apoptotic processGO:00514021420.081
g protein coupled receptor signaling pathwayGO:00071862430.078
regulation of neuron apoptotic processGO:00435231220.074
regulation of secretion by cellGO:19035302490.074
apoptotic signaling pathwayGO:00971903060.074
cytokine productionGO:00018163190.072
telencephalon developmentGO:00215371860.066
oxidation reduction processGO:00551143420.065
amine metabolic processGO:0009308450.063
positive regulation of programmed cell deathGO:00430682180.061
carbohydrate metabolic processGO:00059752300.061
negative regulation of neuron apoptotic processGO:0043524920.059
leukocyte differentiationGO:00025213420.059
cellular ketone metabolic processGO:0042180840.056
regulation of cell migrationGO:00303342190.055
regulation of cell cycleGO:00517262810.055
negative regulation of neuron deathGO:1901215980.055
cellular lipid metabolic processGO:00442553230.054
forebrain developmentGO:00309003020.054
embryonic organ morphogenesisGO:00485622760.053
neuroblast fate determinationGO:000740010.053
positive regulation of cell migrationGO:00303351090.052
appendage developmentGO:00487361660.050
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.049
organic cyclic compound catabolic processGO:19013612950.049
positive regulation of cellular amino acid metabolic processGO:004576430.049
positive regulation of cell deathGO:00109422240.049
mapk cascadeGO:00001652810.048
Human
stem cell fate determinationGO:004886720.048
regulation of organelle organizationGO:00330432890.048
stem cell differentiationGO:00488632680.045
muscle tissue developmentGO:00605373080.045
protein maturationGO:00516041760.044
neuroblast fate commitmentGO:001401710.044
purine nucleotide metabolic processGO:00061633020.044
axonogenesisGO:00074092740.044
glial cell differentiationGO:00100011310.043
ribonucleotide metabolic processGO:00092592910.043
reactive oxygen species metabolic processGO:0072593840.043
myeloid cell differentiationGO:00300992330.042
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.042
neural tube developmentGO:00219151600.041
mesodermal cell migrationGO:000807840.041
hematopoietic progenitor cell differentiationGO:00022441430.040
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.040
synaptic transmission glycinergicGO:006001220.040
compound eye developmentGO:004874910.039
neuroblast differentiationGO:001401620.039
lymphocyte differentiationGO:00300982420.038
midbrain hindbrain boundary morphogenesisGO:002155540.038
neural tube formationGO:00018411080.038
positive regulation of protein phosphorylationGO:00019342420.038
exocytosisGO:00068871210.037
peptidyl amino acid modificationGO:00181933360.037
camera type eye developmentGO:00430102660.037
gamma aminobutyric acid signaling pathwayGO:000721480.037
positive regulation of apoptotic signaling pathwayGO:2001235950.037
positive regulation of neuron projection regenerationGO:007057220.037
regulation of cellular amino acid metabolic processGO:000652150.037
learningGO:0007612980.036
multicellular organism growthGO:00352641610.036
monocarboxylic acid metabolic processGO:00327871910.036
action potentialGO:0001508780.036
regulation of neuron differentiationGO:00456642810.036
organic acid biosynthetic processGO:0016053860.036
male gamete generationGO:00482322850.035
cellular response to histamineGO:007142010.034
connective tissue developmentGO:00614481790.034
regulation of exocytosisGO:0017157610.034
positive regulation of cellular amine metabolic processGO:003324050.034
neuron deathGO:00709971540.034
purine containing compound metabolic processGO:00725213110.034
glycoprotein metabolic processGO:00091001160.033
b cell activationGO:00421131610.033
cerebellum developmentGO:0021549770.033
negative regulation of cellular amino acid metabolic processGO:004576300.033
photoreceptor cell differentiationGO:0046530520.033
cellular response to ammonium ionGO:007124220.033
negative regulation of apoptotic signaling pathwayGO:20012341040.033
glycosylationGO:0070085620.033
development of primary sexual characteristicsGO:00451371430.032
asymmetric neuroblast divisionGO:005505910.032
nucleobase containing small molecule metabolic processGO:00550863520.032
response to histamineGO:003477610.032
erk1 and erk2 cascadeGO:0070371770.032
regulation of protein processingGO:0070613960.031
cell type specific apoptotic processGO:00972852680.031
macromolecule catabolic processGO:00090572810.031
cellular component assembly involved in morphogenesisGO:00109271390.031
homeostasis of number of cellsGO:00488722100.031
renal system developmentGO:00720012250.031
nucleoside metabolic processGO:00091162460.031
embryonic epithelial tube formationGO:00018381300.030
cerebral cortex developmentGO:0021987860.030
aromatic compound catabolic processGO:00194392860.030
regulation of transferase activityGO:00513382630.030
lipid localizationGO:00108761260.030
peptidyl serine phosphorylationGO:0018105740.029
rho protein signal transductionGO:0007266320.029
limb developmentGO:00601731660.029
autonomic nervous system developmentGO:0048483430.029
negative regulation of phosphorylationGO:00423261660.029
regulation of cellular response to stressGO:00801351590.029
Human
regulation of protein localizationGO:00328802310.029
protein glycosylationGO:0006486550.028
bone developmentGO:00603481200.028
axon guidanceGO:00074111410.028
chemotaxisGO:00069352470.028
regionalizationGO:00030023370.028
positive regulation of protein modification processGO:00314012990.027
cellular amine metabolic processGO:0044106440.027
pigmentationGO:0043473710.027
regulation of kinase activityGO:00435492490.027
response to oxidative stressGO:00069791230.027
regulation of secretionGO:00510462740.027
cognitionGO:00508901490.027
fatty acid metabolic processGO:00066311210.027
negative regulation of protein metabolic processGO:00512482820.027
ameboidal type cell migrationGO:00016671280.027
central nervous system neuron differentiationGO:00219531620.026
kidney epithelium developmentGO:00720731210.026
defense response to other organismGO:00985421970.026
response to inorganic substanceGO:0010035960.026
limb morphogenesisGO:00351081490.026
keratinocyte migrationGO:005154630.026
response to light stimulusGO:00094161350.025
circadian regulation of gene expressionGO:0032922480.025
neuroblast proliferationGO:0007405490.025
heterocycle catabolic processGO:00467002800.025
positive regulation of nervous system developmentGO:00519622210.025
cell recognitionGO:0008037830.025
response to growth factorGO:00708481980.025
regulation of apoptotic signaling pathwayGO:20012331970.025
photoreceptor cell developmentGO:0042461400.025
negative regulation of cellular amine metabolic processGO:003323910.025
positive regulation of cell projection organizationGO:0031346950.025
regulation of fatty acid metabolic processGO:0019217280.025
hindbrain developmentGO:00309021280.025
regulation of respiratory system processGO:0044065130.025
organonitrogen compound biosynthetic processGO:19015661920.024
transmembrane transportGO:00550854120.024
palate developmentGO:0060021760.024
regulation of protein serine threonine kinase activityGO:00719001570.024
nucleoside phosphate metabolic processGO:00067533380.024
positive regulation of erk1 and erk2 cascadeGO:0070374470.024
skeletal system developmentGO:00015013560.024
regulation of organ morphogenesisGO:20000271440.024
regulation of cytoskeleton organizationGO:00514931220.024
positive regulation of cell motilityGO:20001471160.024
endocrine system developmentGO:0035270980.024
regulation of hydrolase activityGO:00513362460.024
small gtpase mediated signal transductionGO:0007264970.024
small molecule biosynthetic processGO:00442831320.024
immune response activating signal transductionGO:00027571160.023
regulation of cell adhesionGO:00301551540.023
antimicrobial peptide productionGO:000277520.023
multicellular organismal response to stressGO:0033555620.023
stem cell developmentGO:00488642190.023
negative regulation of cell migrationGO:0030336590.023
primary neural tube formationGO:0014020950.023
inner ear receptor cell differentiationGO:0060113610.023
hexose metabolic processGO:0019318980.022
rhodopsin mediated signaling pathwayGO:001605640.022
microtubule based processGO:00070172360.022
microtubule cytoskeleton organizationGO:00002261570.022
positive regulation of cytokine productionGO:00018191740.022
multicellular organismal signalingGO:0035637910.022
response to radiationGO:00093141650.022
protein processingGO:00164851630.022
glucose homeostasisGO:00425931280.022
protein kinase b signalingGO:0043491740.022
gland developmentGO:00487323300.022
urogenital system developmentGO:00016552610.022
cation transportGO:00068123990.022
fibroblast migrationGO:0010761210.022
positive regulation of phospholipase c activityGO:001086320.022
appendage morphogenesisGO:00351071490.021
regulation of erk1 and erk2 cascadeGO:0070372710.021
regulation of protein kinase activityGO:00458592320.021
embryonic appendage morphogenesisGO:00351131260.021
epithelial cell developmentGO:00020641590.021
epithelial cell proliferationGO:00506731740.021
maintenance of locationGO:0051235890.021
regulation of sequence specific dna binding transcription factor activityGO:00510901060.021
negative regulation of synapse maturationGO:200029720.021
kidney morphogenesisGO:0060993830.021
peptidyl tyrosine phosphorylationGO:00181081430.021
cell activation involved in immune responseGO:00022631260.021
neural precursor cell proliferationGO:00613511210.021
defense response to bacteriumGO:00427421190.021
respiratory system developmentGO:00605411900.021
regulation of map kinase activityGO:00434051200.020
nuclear importGO:0051170950.020
single fertilizationGO:0007338820.020
engulfment of apoptotic cellGO:004365230.020
regulation of neuron projection developmentGO:00109751690.020
positive regulation of protein kinase activityGO:00458601440.020
fear responseGO:0042596330.020
epithelial tube morphogenesisGO:00605623030.020
central nervous system projection neuron axonogenesisGO:0021952210.020
negative regulation of cellular protein metabolic processGO:00322692470.020
negative regulation of intracellular signal transductionGO:19025321670.020
organelle assemblyGO:00709251770.020
gonad developmentGO:00084061410.020
positive regulation of fatty acid biosynthetic processGO:004572330.020
epithelial tube formationGO:00721751300.020
purine nucleoside triphosphate metabolic processGO:00091442260.019
blood circulationGO:00080151950.019
purine ribonucleotide metabolic processGO:00091502900.019
fat cell differentiationGO:00454441600.019
anatomical structure homeostasisGO:00602491450.019
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.019
negative regulation of cell fate specificationGO:000999640.019
antibacterial peptide productionGO:000277820.019
regulation of fat cell differentiationGO:0045598810.019
organelle localizationGO:00516401790.019
regulation of phospholipase c activityGO:190027430.019
sensory perceptionGO:00076002450.019
nucleoside phosphate catabolic processGO:19012922220.019
cell fate specificationGO:0001708720.019
antibacterial peptide biosynthetic processGO:000278020.018
response to molecule of bacterial originGO:00022371430.018
regulation of fatty acid biosynthetic processGO:0042304120.018
angiogenesisGO:00015252010.018
protein modification by small protein conjugation or removalGO:00706472070.018
neural tube closureGO:0001843900.018
stress activated mapk cascadeGO:0051403800.018
Human
myeloid cell homeostasisGO:00022621140.018
non canonical wnt signaling pathwayGO:0035567330.018
ribose phosphate metabolic processGO:00196932910.018
negative regulation of cellular component organizationGO:00511291940.018
carboxylic acid biosynthetic processGO:0046394860.018
inner ear receptor cell developmentGO:0060119390.018
posttranscriptional regulation of gene expressionGO:00106081550.018
kidney developmentGO:00018222130.018
amide transportGO:00428861380.018
locomotory behaviorGO:00076261950.018
regulation of striated muscle cell differentiationGO:0051153810.018
glucose metabolic processGO:0006006920.018
rhythmic processGO:00485111740.018
skeletal system morphogenesisGO:00487052030.018
cellular nitrogen compound catabolic processGO:00442702800.018
regulation of protein maturationGO:1903317960.018
regulation of membrane potentialGO:00423911920.018
regulation of cell shapeGO:0008360390.017
smoothened signaling pathwayGO:00072241050.017
chloride transportGO:0006821320.017
regulation of cellular catabolic processGO:00313292420.017
nucleotide catabolic processGO:00091662170.017
cell adhesionGO:00071553290.017
regulation of chemotaxisGO:0050920530.017
positive regulation of neuron projection developmentGO:0010976790.017
response to insulinGO:00328681000.017
regulation of eosinophil migrationGO:200041620.017
spinal cord developmentGO:0021510810.017
positive regulation of hydrolase activityGO:00513451480.017
regulation of cell projection organizationGO:00313442060.017
mechanoreceptor differentiationGO:0042490670.017
learning or memoryGO:00076111480.017
production of molecular mediator of immune responseGO:00024401030.017
regulation of mapk cascadeGO:00434082480.017
Human
positive regulation of lymphocyte activationGO:00512511400.017
negative regulation of molecular functionGO:00440922580.017
digestive system developmentGO:00551232000.017
brain derived neurotrophic factor receptor signaling pathwayGO:003154730.017
skeletal muscle cell differentiationGO:0035914660.017
adult locomotory behaviorGO:0008344910.017
trunk neural crest cell migrationGO:003648440.017
neurotransmitter transportGO:0006836760.017
antimicrobial peptide biosynthetic processGO:000277720.017
skin developmentGO:00435882200.017
cation homeostasisGO:00550802120.016
regulation of protein kinase b signalingGO:0051896560.016
leukocyte migrationGO:00509001240.016
regulation of intracellular transportGO:00323861590.016
tube closureGO:0060606910.016
cellular response to dna damage stimulusGO:00069742070.016
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
dna metabolic processGO:00062593030.016
defense response to fungusGO:0050832120.016
synaptic vesicle transportGO:0048489570.016
regulation of multi organism processGO:00439001110.016
negative regulation of hydrolase activityGO:0051346710.016
cell fate determination involved in pattern specificationGO:006058210.016
negative regulation of growthGO:0045926990.016
response to starvationGO:0042594650.016
multi multicellular organism processGO:00447061090.016
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.016
protein catabolic processGO:00301632210.016
response to uvGO:0009411440.016
synaptic transmissionGO:00072683290.016
regulation of anoikisGO:200020920.016
carbohydrate derivative biosynthetic processGO:19011371830.016
cellular ion homeostasisGO:00068731650.016
cellular response to growth factor stimulusGO:00713631970.016
innate immune responseGO:00450871570.015
macromolecule glycosylationGO:0043413550.015
regulation of intracellular protein transportGO:0033157820.015
organelle fissionGO:00482851700.015
canonical wnt signaling pathwayGO:00600701300.015
regulation of neuron deathGO:19012141340.015
peptide secretionGO:00027901140.015
ras protein signal transductionGO:0007265770.015
cellular response to inorganic substanceGO:0071241370.015
asymmetric stem cell divisionGO:009872230.015
nephron epithelium developmentGO:0072009920.015
purine nucleotide catabolic processGO:00061952110.015
cellular response to oxidative stressGO:0034599760.015
regulation of bmp signaling pathwayGO:0030510600.015
formation of organ boundaryGO:001016010.015
skeletal muscle organ developmentGO:00605381630.015
blastocyst developmentGO:0001824800.015
negative regulation of cell cycleGO:00457861230.015
gonadotrophin releasing hormone neuronal migration to the hypothalamusGO:002182830.015
metencephalon developmentGO:0022037890.015
myotube differentiationGO:00149021050.015
neural tube patterningGO:0021532430.015
regulation of antimicrobial peptide biosynthetic processGO:000280510.015
i kappab kinase nf kappab signalingGO:0007249850.015
response to ionizing radiationGO:0010212420.015
negative regulation of phosphorus metabolic processGO:00105631840.015
embryonic placenta developmentGO:0001892980.014
cellular homeostasisGO:00197252400.014
cellular response to cytokine stimulusGO:00713451890.014
nucleoside triphosphate metabolic processGO:00091412300.014
hypothalamic tangential migration using cell axon interactionsGO:002185630.014
glycosyl compound catabolic processGO:19016582060.014
cellular metal ion homeostasisGO:00068751510.014
regulation of cellular component sizeGO:00325351210.014
cartilage developmentGO:00512161400.014
endodermal cell fate specificationGO:000171440.014
positive regulation of cellular catabolic processGO:00313311480.014
protein complex disassemblyGO:0043241400.014
lipid biosynthetic processGO:00086101790.014
neurotrophin signaling pathwayGO:0038179120.014
mitotic cell cycleGO:00002781950.014
regulation of protein depolymerizationGO:1901879260.014
regulation of neural retina developmentGO:006107430.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.014
carbohydrate derivative catabolic processGO:19011362310.014
extracellular matrix organizationGO:00301981470.014
peptidyl serine modificationGO:0018209830.014
dna repairGO:00062811070.014
defense response to gram positive bacteriumGO:0050830500.014
glycoprotein biosynthetic processGO:0009101890.014
transforming growth factor beta receptor signaling pathwayGO:0007179710.014
positive regulation of protein serine threonine kinase activityGO:00719021060.014
sequestering of calcium ionGO:0051208180.014
t cell activationGO:00421102890.014
regulation of cellular response to growth factor stimulusGO:0090287820.014
embryonic limb morphogenesisGO:00303261260.014
lung developmentGO:00303241640.014
inorganic anion transportGO:0015698430.014
tissue homeostasisGO:00018941150.014
spermatid differentiationGO:00485151150.014
calcium mediated signaling using intracellular calcium sourceGO:003558430.014
regulation of myeloid cell differentiationGO:0045637960.014
sympathetic neuron projection guidanceGO:009749140.014
reflexGO:0060004220.014
protein importGO:00170381010.014
organic anion transportGO:00157111370.014
peptide transportGO:00158331330.014
actin cytoskeleton organizationGO:00300362200.013
organ regenerationGO:003110020.013
interleukin 8 productionGO:003263740.013
lipid homeostasisGO:0055088630.013
regulation of membrane protein ectodomain proteolysisGO:005104330.013
protein targetingGO:00066051430.013
synaptic vesicle localizationGO:0097479590.013
regulation of respiratory gaseous exchangeGO:0043576180.013
negative regulation of organelle organizationGO:0010639900.013
membrane hyperpolarizationGO:0060081210.013
regulation of bindingGO:00510981110.013
regulation of body fluid levelsGO:00508781620.013
macromolecular complex disassemblyGO:0032984430.013
positive regulation of keratinocyte proliferationGO:001083840.013
activation of mapk activityGO:0000187590.013
regulation of lipid metabolic processGO:00192161180.013
regulation of antimicrobial peptide productionGO:000278410.013
protein polymerizationGO:0051258570.013
divalent inorganic cation homeostasisGO:00725071380.013
tube formationGO:00351481400.013
interleukin 12 secretionGO:007261030.013
membrane fusionGO:0061025380.013
transmission of nerve impulseGO:0019226760.013
ribonucleoside catabolic processGO:00424542060.013
phagocytosisGO:0006909660.013
immune response regulating signaling pathwayGO:00027641250.013
cellular carbohydrate metabolic processGO:00442621190.013
nucleoside triphosphate catabolic processGO:00091432050.013
trunk segmentationGO:003529040.013
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.013
positive regulation of cell activationGO:00508671580.013
establishment of synaptic vesicle localizationGO:0097480570.013
ribonucleoside triphosphate catabolic processGO:00092031990.013
ventral trunk neural crest cell migrationGO:003648640.013
somitogenesisGO:0001756690.013
response to drugGO:0042493750.013
skeletal muscle fiber developmentGO:0048741580.013
pallium developmentGO:00215431200.013
neuron migrationGO:00017641220.012
positive regulation of organelle organizationGO:00106381280.012
dephosphorylationGO:00163111290.012
mesenchymal cell developmentGO:0014031930.012
regulation of peptidyl serine phosphorylationGO:0033135390.012
cellular response to hormone stimulusGO:00328701500.012
neuromuscular processGO:0050905990.012
myeloid leukocyte differentiationGO:00025731190.012
negative regulation of anoikisGO:200081120.012
cellular chemical homeostasisGO:00550822150.012
calcium ion dependent exocytosisGO:0017156350.012
embryonic skeletal system developmentGO:00487061200.012
regulation of transporter activityGO:0032409570.012
sensory organ morphogenesisGO:00905962420.012
anion transportGO:00068201770.012
purine ribonucleotide catabolic processGO:00091542080.012
cellular protein complex assemblyGO:00436231160.012
fatty acid biosynthetic processGO:0006633410.012
protein modification by small protein conjugationGO:00324461870.012
regulation of muscle tissue developmentGO:1901861970.012
leukocyte activation involved in immune responseGO:00023661260.012
regulation of ion transmembrane transportGO:00347651190.012
cilium morphogenesisGO:00602711020.012
regulation of wnt signaling pathwayGO:00301111230.012
monocarboxylic acid biosynthetic processGO:0072330610.012
hindbrain morphogenesisGO:0021575460.012
positive regulation of wnt signaling pathwayGO:0030177450.012
muscle cell developmentGO:00550011330.012
cellular macromolecule catabolic processGO:00442652060.012
intracellular receptor signaling pathwayGO:0030522740.012
regulation of antimicrobial humoral responseGO:000275930.012
negative regulation of cell cycle phase transitionGO:1901988480.012
regulation of peptidase activityGO:0052547960.012
mesenchymal cell proliferationGO:0010463440.012
single organism cell adhesionGO:00986021560.012
dendrite developmentGO:00163581150.012
negative regulation of synaptic vesicle exocytosisGO:200030130.012
regulation of cytokine productionGO:00018172660.012
regulation of reproductive processGO:2000241660.012
organonitrogen compound catabolic processGO:19015652640.012
morphogenesis of embryonic epitheliumGO:00163311590.012
positive regulation of endopeptidase activityGO:0010950430.012
positive regulation of antimicrobial peptide productionGO:000222510.012
spermatid developmentGO:00072861080.012
gastrulationGO:00073691160.012
regulation of anatomical structure sizeGO:00900661780.012
negative regulation of phagocytosisGO:005076540.011
nucleocytoplasmic transportGO:00069131390.011
eye photoreceptor cell developmentGO:0042462310.011
regulation of interleukin 8 productionGO:003267730.011
stem cell proliferationGO:00720891170.011
bmp signaling pathwayGO:0030509930.011
regulation of microvillus assemblyGO:003253430.011
eosinophil migrationGO:007267730.011
vegf activated neuropilin signaling pathwayGO:003819020.011
b cell activation involved in immune responseGO:0002312500.011
embryonic heart tube developmentGO:0035050650.011
cytokine biosynthetic processGO:0042089680.011
regulation of nucleotide metabolic processGO:00061401690.011
axon ensheathmentGO:0008366760.011
regulation of cell activationGO:00508652890.011
divalent inorganic cation transportGO:00725111780.011

Mid1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.043
disease of cellular proliferationDOID:1456600.043
organ system cancerDOID:005068600.041
nervous system diseaseDOID:86300.027
disease of anatomical entityDOID:700.027
immune system diseaseDOID:291400.020
hematopoietic system diseaseDOID:7400.020
musculoskeletal system diseaseDOID:1700.019
connective tissue diseaseDOID:6500.017
bone diseaseDOID:008000100.016
central nervous system diseaseDOID:33100.015
lysosomal storage diseaseDOID:321100.012
disease of metabolismDOID:001466700.012
inherited metabolic disorderDOID:65500.012
sensory system diseaseDOID:005015500.012
eye diseaseDOID:561400.012
eye and adnexa diseaseDOID:149200.012