Mus musculus

288 known processes

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

(Aliases: me,hcp,Ptp1C,Hcph,SHP-1,motheaten)

Ptpn6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
amine metabolic processGO:0009308450.987
leukocyte proliferationGO:00706611720.973
b cell receptor signaling pathwayGO:0050853200.960
immune response activating cell surface receptor signaling pathwayGO:0002429720.920
lymphocyte proliferationGO:00466511640.916
actin cytoskeleton organizationGO:00300362200.902
leukocyte differentiationGO:00025213420.879
regulation of hydrolase activityGO:00513362460.780
peptidyl amino acid modificationGO:00181933360.777
peptidyl tyrosine phosphorylationGO:00181081430.755
t cell proliferationGO:00420981200.743
antigen receptor mediated signaling pathwayGO:0050851640.736
regulation of lymphocyte proliferationGO:00506701170.717
positive regulation of hydrolase activityGO:00513451480.709
positive regulation of gamma delta t cell differentiationGO:004558860.695
regulation of actin polymerization or depolymerizationGO:0008064450.684
b cell activation involved in immune responseGO:0002312500.679
ras protein signal transductionGO:0007265770.678
lymphocyte differentiationGO:00300982420.670
immune response regulating signaling pathwayGO:00027641250.647
cellular lipid metabolic processGO:00442553230.632
Mouse
t cell activationGO:00421102890.608
activation of immune responseGO:00022531380.603
regulation of apoptotic signaling pathwayGO:20012331970.598
regulation of cell migrationGO:00303342190.593
cytokine biosynthetic processGO:0042089680.582
positive regulation of apoptotic processGO:00430652170.573
response to molecule of bacterial originGO:00022371430.564
regulation of vesicle mediated transportGO:00606271390.558
positive regulation of protein modification processGO:00314012990.551
Mouse
organonitrogen compound catabolic processGO:19015652640.538
cellular ketone metabolic processGO:0042180840.533
immune response regulating cell surface receptor signaling pathwayGO:0002768800.514
hemostasisGO:0007599780.502
response to peptideGO:19016521360.500
b cell activationGO:00421131610.495
axonogenesisGO:00074092740.475
Mouse
regulation of cell cycleGO:00517262810.473
Human Mouse
leukocyte activation involved in immune responseGO:00023661260.465
b cell differentiationGO:0030183780.463
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.455
multicellular organismal homeostasisGO:00488711640.442
regulation of cellular amine metabolic processGO:0033238200.433
actin polymerization or depolymerizationGO:0008154540.432
cellular amino acid metabolic processGO:00065201030.426
guanosine containing compound metabolic processGO:19010681440.396
defense response to other organismGO:00985421970.388
regulation of cell adhesionGO:00301551540.386
positive regulation of cell developmentGO:00107202370.376
adaptive immune responseGO:00022501550.372
positive regulation of nucleotide metabolic processGO:00459811140.371
regulation of cellular catabolic processGO:00313292420.367
positive regulation of programmed cell deathGO:00430682180.365
nucleoside catabolic processGO:00091642060.351
regulation of organelle organizationGO:00330432890.349
cellular amine metabolic processGO:0044106440.340
positive t cell selectionGO:0043368230.328
positive regulation of cytokine biosynthetic processGO:0042108400.327
b cell proliferationGO:0042100530.320
mast cell proliferationGO:007066240.319
immune response activating signal transductionGO:00027571160.315
regulation of lymphocyte activationGO:00512492400.315
reactive oxygen species metabolic processGO:0072593840.310
negative regulation of protein metabolic processGO:00512482820.307
regulation of myeloid leukocyte differentiationGO:0002761580.307
regulation of t cell activationGO:00508631700.303
positive regulation of cellular amino acid metabolic processGO:004576430.301
ribonucleoside catabolic processGO:00424542060.300
positive regulation of cell deathGO:00109422240.293
purine ribonucleotide metabolic processGO:00091502900.290
muscle cell differentiationGO:00426922610.289
positive regulation of gtp catabolic processGO:0033126850.274
ribonucleoside triphosphate metabolic processGO:00091992200.271
ion transmembrane transportGO:00342203610.269
response to lipopolysaccharideGO:00324961280.268
regulation of cell activationGO:00508652890.268
platelet activationGO:0030168400.262
gland developmentGO:00487323300.259
purine nucleoside triphosphate metabolic processGO:00091442260.255
glycosyl compound catabolic processGO:19016582060.253
nucleoside triphosphate catabolic processGO:00091432050.252
telencephalon developmentGO:00215371860.251
lipid localizationGO:00108761260.248
Mouse
regulation of mast cell proliferationGO:007066640.248
cellular response to lipopolysaccharideGO:0071222770.247
positive regulation of myeloid leukocyte differentiationGO:0002763260.246
protein processingGO:00164851630.246
regulation of actin filament based processGO:0032970990.244
regulation of cell shapeGO:0008360390.241
regulation of cell motilityGO:20001452360.239
t cell selectionGO:0045058340.237
myeloid dendritic cell activationGO:0001773250.235
histamine production involved in inflammatory responseGO:000234910.234
negative regulation of protein serine threonine kinase activityGO:0071901490.230
morphogenesis of a branching structureGO:00017632030.230
purine nucleoside metabolic processGO:00422782410.227
positive regulation of protein phosphorylationGO:00019342420.226
Mouse
macromolecule catabolic processGO:00090572810.226
maintenance of locationGO:0051235890.222
organelle assemblyGO:00709251770.222
positive regulation of cellular catabolic processGO:00313311480.221
regulation of cellular ketone metabolic processGO:0010565660.218
small gtpase mediated signal transductionGO:0007264970.216
activation of rac gtpase activityGO:003286320.216
phagocytosisGO:0006909660.215
Fly
regulation of intracellular transportGO:00323861590.214
regulation of purine nucleotide metabolic processGO:19005421690.213
rho protein signal transductionGO:0007266320.206
negative regulation of cellular amino acid metabolic processGO:004576300.204
neuron projection guidanceGO:00974851410.202
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.201
negative regulation of molecular functionGO:00440922580.200
positive regulation of myeloid cell differentiationGO:0045639430.200
cell type specific apoptotic processGO:00972852680.199
cellular response to biotic stimulusGO:0071216920.197
positive regulation of gamma delta t cell activationGO:004664560.195
interferon beta biosynthetic processGO:004535040.193
apoptotic signaling pathwayGO:00971903060.193
ribonucleotide catabolic processGO:00092612080.191
skeletal muscle organ developmentGO:00605381630.190
regulation of body fluid levelsGO:00508781620.188
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.188
nuclear divisionGO:00002801580.186
gtp catabolic processGO:00061841430.184
regulation of myeloid cell differentiationGO:0045637960.182
regulation of gamma delta t cell differentiationGO:004558690.182
glycosyl compound metabolic processGO:19016572460.181
nucleotide metabolic processGO:00091173320.181
regulation of antigen receptor mediated signaling pathwayGO:0050854290.181
positive regulation of t cell activationGO:00508701010.181
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.178
extrinsic apoptotic signaling pathwayGO:00971911260.178
regulation of endopeptidase activityGO:0052548890.176
regulation of erythrocyte differentiationGO:0045646230.171
syncytium formation by plasma membrane fusionGO:0000768420.171
dna recombinationGO:0006310920.166
regulation of t cell proliferationGO:0042129920.165
calcium ion transportGO:00068161590.165
alpha beta t cell differentiationGO:0046632690.164
aromatic compound catabolic processGO:00194392860.162
t cell apoptotic processGO:0070231390.162
cd8 positive alpha beta t cell proliferationGO:003574010.159
leukocyte apoptotic processGO:0071887710.157
ribonucleoside triphosphate catabolic processGO:00092031990.157
lymphocyte homeostasisGO:0002260640.155
negative regulation of homeostatic processGO:0032845710.155
cell adhesionGO:00071553290.154
purine ribonucleoside triphosphate metabolic processGO:00092052200.152
regulation of nucleotide catabolic processGO:00308111220.150
heterocycle catabolic processGO:00467002800.150
regulation of neuron projection developmentGO:00109751690.149
regulation of peptidyl tyrosine phosphorylationGO:0050730930.148
negative regulation of cell activationGO:00508661110.148
regulation of proteolysisGO:00301621640.148
regulation of mast cell differentiationGO:006037530.148
axon guidanceGO:00074111410.145
endocytosisGO:00068971680.145
Fly
leukocyte chemotaxisGO:0030595690.144
regulation of cellular amino acid metabolic processGO:000652150.144
cation homeostasisGO:00550802120.143
substrate dependent cell migration cell extensionGO:000693040.142
positive regulation of b cell differentiationGO:0045579130.142
positive regulation of adaptive immune responseGO:0002821610.142
nucleotide catabolic processGO:00091662170.142
lymphocyte activation involved in immune responseGO:0002285930.141
negative regulation of b cell receptor signaling pathwayGO:005085940.140
chemotaxisGO:00069352470.140
regulation of b cell activationGO:0050864810.140
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.139
regulation of nucleoside metabolic processGO:00091181300.138
ribose phosphate metabolic processGO:00196932910.138
cellular response to dna damage stimulusGO:00069742070.137
Mouse
meiotic cell cycleGO:00513211220.137
regulation of myeloid dendritic cell activationGO:003088550.136
negative regulation of immune system processGO:00026832090.136
regulation of ion transmembrane transportGO:00347651190.135
regulation of actin filament lengthGO:0030832450.134
purine nucleotide catabolic processGO:00061952110.134
positive regulation of cellular amine metabolic processGO:003324050.132
organelle fissionGO:00482851700.132
actin filament organizationGO:00070151130.131
skin developmentGO:00435882200.130
digestive tract developmentGO:00485651900.129
sensory perceptionGO:00076002450.129
ribonucleotide metabolic processGO:00092592910.129
macromolecule methylationGO:00434141200.129
cell activation involved in immune responseGO:00022631260.128
stem cell developmentGO:00488642190.126
cell divisionGO:00513011200.126
histamine secretion by mast cellGO:000255310.126
morphogenesis of embryonic epitheliumGO:00163311590.126
regulation of b cell differentiationGO:0045577230.126
neutrophil differentiationGO:003022330.125
protein import into nucleusGO:0006606950.124
negative regulation of cellular component organizationGO:00511291940.123
regulation of toll like receptor signaling pathwayGO:0034121200.123
leukocyte cell cell adhesionGO:0007159140.123
negative regulation of intracellular signal transductionGO:19025321670.122
regulation of gamma delta t cell activationGO:004664390.122
purine ribonucleotide catabolic processGO:00091542080.122
gtp metabolic processGO:00460391440.122
positive regulation of gtpase activityGO:0043547850.121
cation transportGO:00068123990.119
regulation of actin filament polymerizationGO:0030833380.118
regulation of actin nucleationGO:005112540.117
somatic recombination of immunoglobulin gene segmentsGO:0016447420.117
regulation of toll like receptor 2 signaling pathwayGO:003413530.116
regulation of protein complex assemblyGO:0043254830.116
regulation of neutrophil differentiationGO:004565820.116
organic anion transportGO:00157111370.114
positive regulation of lipid kinase activityGO:0090218110.114
negative regulation of leukocyte differentiationGO:1902106510.114
negative regulation of cellular amine metabolic processGO:003323910.113
regulation of myd88 independent toll like receptor signaling pathwayGO:003412710.113
positive regulation of rho gtpase activityGO:0032321410.113
regulation of peptidase activityGO:0052547960.113
regulation of ion transportGO:00432692150.113
negative regulation of synapse assemblyGO:005196430.112
multicellular organism growthGO:00352641610.111
Mouse
dna metabolic processGO:00062593030.111
negative regulation of toll like receptor signaling pathwayGO:0034122140.110
regulation of phosphatidylinositol 3 kinase activityGO:0043551140.110
t helper cell lineage commitmentGO:000229560.109
gamma delta t cell differentiationGO:0042492110.108
t cell differentiationGO:00302171740.108
regulation of neuron differentiationGO:00456642810.107
Fly
membrane organizationGO:00610242450.107
Fly
negative regulation of organelle organizationGO:0010639900.106
neuron migrationGO:00017641220.105
positive regulation of interferon alpha productionGO:003272740.105
microtubule cytoskeleton organizationGO:00002261570.105
regulation of lipid metabolic processGO:00192161180.105
peptidyl tyrosine modificationGO:00182121450.104
cytosolic calcium ion transportGO:0060401480.104
phospholipid metabolic processGO:0006644870.103
mitotic cell cycleGO:00002781950.103
cell chemotaxisGO:0060326810.103
digestive system developmentGO:00551232000.102
regulation of actin cytoskeleton organizationGO:0032956840.102
lipopolysaccharide mediated signaling pathwayGO:0031663250.102
regulation of metal ion transportGO:00109591060.100
actin filament polymerizationGO:0030041440.099
myeloid leukocyte differentiationGO:00025731190.098
positive regulation of map kinase activityGO:0043406840.098
Mouse
angiogenesisGO:00015252010.098
negative regulation of phosphate metabolic processGO:00459361840.098
negative regulation of regulatory t cell differentiationGO:004559020.097
positive regulation of purine nucleotide metabolic processGO:19005441140.096
wound healingGO:00420601570.096
regulation of cd8 positive alpha beta t cell proliferationGO:200056410.096
tyrosine phosphorylation of stat proteinGO:0007260230.096
muscle cell developmentGO:00550011330.095
regulation of nucleotide metabolic processGO:00061401690.095
nucleoside metabolic processGO:00091162460.095
negative regulation of toll like receptor 2 signaling pathwayGO:003413630.095
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.095
gamma delta t cell activationGO:0046629130.094
microtubule based processGO:00070172360.094
cytokine metabolic processGO:0042107710.093
regulation of jak stat cascadeGO:0046425340.093
positive regulation of cell cycleGO:0045787920.093
Mouse
regulation of cytoskeleton organizationGO:00514931220.093
arp2 3 complex mediated actin nucleationGO:003431430.093
myotube differentiationGO:00149021050.092
exocytosisGO:00068871210.092
positive regulation of podosome assemblyGO:007180330.092
protein polymerizationGO:0051258570.091
stem cell differentiationGO:00488632680.091
dendrite developmentGO:00163581150.090
regulation of cellular component sizeGO:00325351210.090
positive regulation of type i interferon mediated signaling pathwayGO:006034040.089
coagulationGO:0050817780.089
negative regulation of hydrolase activityGO:0051346710.089
g protein coupled receptor signaling pathwayGO:00071862430.089
protein autophosphorylationGO:0046777610.088
regulation of protein bindingGO:0043393600.087
ribonucleoside metabolic processGO:00091192450.087
syncytium formationGO:0006949430.087
regulation of monocyte extravasationGO:200043720.087
regulation of nuclear divisionGO:0051783560.086
regulation of interleukin 2 biosynthetic processGO:0045076130.086
pallium developmentGO:00215431200.086
spermatogenesisGO:00072832840.085
vesicle fusionGO:0006906160.085
somatic diversification of immune receptorsGO:0002200530.085
response to peptide hormoneGO:00434341270.085
organic cyclic compound catabolic processGO:19013612950.085
protein catabolic processGO:00301632210.084
purine nucleoside triphosphate catabolic processGO:00091462030.084
organic hydroxy compound metabolic processGO:19016152030.084
positive regulation of actin nucleationGO:005112730.083
immunoglobulin mediated immune responseGO:0016064690.083
endoderm developmentGO:0007492450.083
epidermis developmentGO:00085441870.083
production of molecular mediator involved in inflammatory responseGO:0002532210.082
gliogenesisGO:00420631410.081
regulation of leukocyte differentiationGO:19021051590.081
positive regulation of proteolysisGO:0045862850.080
cellular ion homeostasisGO:00068731650.080
regulation of mitotic cell cycleGO:00073461260.079
Human Mouse
epithelial cell proliferationGO:00506731740.079
positive regulation of bindingGO:0051099490.079
positive regulation of b cell receptor signaling pathwayGO:005086140.078
erythrocyte differentiationGO:0030218880.078
mammary gland epithelium developmentGO:0061180650.077
cellular metal ion homeostasisGO:00068751510.076
negative regulation of phosphorus metabolic processGO:00105631840.076
immune response inhibiting cell surface receptor signaling pathwayGO:000276730.076
negative regulation of erythrocyte differentiationGO:004564750.076
positive regulation of mitotic cell cycleGO:0045931410.075
Mouse
myeloid leukocyte activationGO:0002274830.075
neutrophil migrationGO:1990266370.075
nucleoside phosphate metabolic processGO:00067533380.075
keratinocyte differentiationGO:0030216480.075
meiotic nuclear divisionGO:00071261150.075
somatic cell dna recombinationGO:0016444510.074
cd24 biosynthetic processGO:003572410.073
myd88 independent toll like receptor signaling pathwayGO:000275630.073
methylationGO:00322591340.073
dna methylationGO:0006306430.073
zymogen activationGO:0031638410.073
cd4 positive alpha beta t cell lineage commitmentGO:004337360.073
regulation of phospholipase c activityGO:190027430.073
regulation of gtp catabolic processGO:00331241130.072
mast cell activationGO:0045576270.072
myeloid dendritic cell differentiationGO:0043011160.072
positive regulation of rac gtpase activityGO:0032855140.072
purine ribonucleoside catabolic processGO:00461302050.072
histone acetylationGO:0016573410.072
lipid transportGO:0006869980.071
Mouse
male gamete generationGO:00482322850.071
vesicle organizationGO:0016050600.070
purine containing compound catabolic processGO:00725232130.070
activation of meiosis involved in egg activationGO:006046620.070
positive regulation of glial cell proliferationGO:006025240.070
forebrain developmentGO:00309003020.070
regulation of cytokine biosynthetic processGO:0042035590.070
regulation of rho gtpase activityGO:0032319580.069
homeostasis of number of cellsGO:00488722100.069
regulation of ras protein signal transductionGO:00465781140.069
nucleoside triphosphate metabolic processGO:00091412300.069
positive regulation of purine nucleotide catabolic processGO:0033123880.069
organelle fusionGO:0048284280.068
granulocyte chemotaxisGO:0071621390.068
jak stat cascadeGO:0007259420.068
regulation of defense response to virusGO:0050688180.068
nucleoside phosphate catabolic processGO:19012922220.068
cellular nitrogen compound catabolic processGO:00442702800.067
anatomical structure homeostasisGO:00602491450.066
regulation of homotypic cell cell adhesionGO:0034110130.066
regulation of transferase activityGO:00513382630.066
oxidation reduction processGO:00551143420.065
negative regulation of cell proliferationGO:00082852960.065
nucleobase containing small molecule metabolic processGO:00550863520.065
protein maturationGO:00516041760.065
striated muscle tissue developmentGO:00147062930.065
purine ribonucleoside triphosphate catabolic processGO:00092071990.065
regulation of ras gtpase activityGO:0032318880.064
striated muscle cell developmentGO:00550021250.064
substrate dependent cell migrationGO:0006929180.063
regulation of bindingGO:00510981110.063
progesterone metabolic processGO:004244840.063
glycerolipid metabolic processGO:00464861220.063
Mouse
regulation of podosome assemblyGO:007180130.063
osteoclast differentiationGO:0030316620.063
positive regulation of neuron differentiationGO:00456661410.063
organophosphate catabolic processGO:00464342320.062
establishment or maintenance of cell polarityGO:0007163860.062
Fly
regulation of purine nucleotide catabolic processGO:00331211220.062
positive regulation of leukocyte differentiationGO:1902107860.061
fc receptor mediated inhibitory signaling pathwayGO:000277410.061
purine nucleoside catabolic processGO:00061522050.061
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.061
purine nucleotide metabolic processGO:00061633020.061
ameboidal type cell migrationGO:00016671280.061
Fly
substrate adhesion dependent cell spreadingGO:0034446300.061
peptidyl serine modificationGO:0018209830.060
intrinsic apoptotic signaling pathwayGO:00971931320.060
notch signaling pathwayGO:0007219710.060
cellular response to cytokine stimulusGO:00713451890.059
t cell receptor signaling pathwayGO:0050852460.059
regulation of dendritic cell apoptotic processGO:200066830.059
positive regulation of cell motilityGO:20001471160.059
female gamete generationGO:0007292740.059
Fly
leukocyte mediated immunityGO:00024431740.058
myeloid cell homeostasisGO:00022621140.058
b 1 b cell differentiationGO:000192330.058
negative regulation of myeloid cell differentiationGO:0045638380.057
mature b cell differentiation involved in immune responseGO:000231390.057
cellular protein complex assemblyGO:00436231160.056
purine ribonucleoside metabolic processGO:00461282410.056
negative regulation of cell developmentGO:00107211690.055
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.055
regulation of cysteine type endopeptidase activityGO:2000116650.055
alpha beta t cell activationGO:0046631910.054
organelle localizationGO:00516401790.054
negative regulation of apoptotic signaling pathwayGO:20012341040.054
peptidyl serine phosphorylationGO:0018105740.054
negative regulation of kinase activityGO:0033673810.054
regulation of homeostatic processGO:00328441820.053
positive regulation of endopeptidase activityGO:0010950430.053
dephosphorylationGO:00163111290.053
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic processGO:004542520.053
positive regulation of cell migrationGO:00303351090.053
leukocyte homeostasisGO:0001776790.052
myosin filament assemblyGO:003103420.052
regulation of cellular component biogenesisGO:00440871810.052
germ cell developmentGO:00072811850.052
Fly
regulation of transporter activityGO:0032409570.052
positive regulation of interleukin 2 productionGO:0032743190.051
regulation of b cell proliferationGO:0030888390.051
immune response inhibiting signal transductionGO:000276540.051
mitotic cell cycle processGO:19030471590.051
Human
negative regulation of cellular protein metabolic processGO:00322692470.051
stem cell maintenanceGO:00198271300.050
regulation of response to woundingGO:19030341890.050
transmembrane transportGO:00550854120.050
regulation of reactive oxygen species biosynthetic processGO:190342620.050
alpha beta t cell lineage commitmentGO:000236370.050
rna dependent dna replicationGO:000627830.050
organonitrogen compound biosynthetic processGO:19015661920.050
skeletal system developmentGO:00015013560.049
cytoplasmic transportGO:00164822340.049
glial cell differentiationGO:00100011310.049
negative regulation of phosphorylationGO:00423261660.049
regulation of protein kinase activityGO:00458592320.049
platelet aggregationGO:0070527200.049
somatic diversification of immunoglobulinsGO:0016445430.049
embryonic appendage morphogenesisGO:00351131260.049
negative regulation of monocyte extravasationGO:200043810.048
cellular chemical homeostasisGO:00550822150.048
blood vessel morphogenesisGO:00485142850.048
regulation of b cell receptor signaling pathwayGO:005085590.048
negative regulation of nik nf kappab signalingGO:190122320.048
organic acid transportGO:00158491010.048
cd4 positive alpha beta t cell activationGO:0035710450.048
response to granulocyte macrophage colony stimulating factorGO:009701230.047
appendage developmentGO:00487361660.047
response to drugGO:0042493750.047
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.047
regulation of protein serine threonine kinase activityGO:00719001570.047
regulation of notch signaling pathwayGO:0008593350.047
metal ion homeostasisGO:00550651890.046
membrane fusionGO:0061025380.046
positive regulation of nucleoside metabolic processGO:0045979910.046
positive regulation of antigen receptor mediated signaling pathwayGO:005085790.046
neutrophil degranulationGO:004331260.046
pigment metabolic processGO:0042440320.046
sulfur compound metabolic processGO:00067901000.045
regulation of lipid kinase activityGO:0043550140.045
leukocyte migrationGO:00509001240.045
chromatin organizationGO:00063252060.045
embryonic epithelial tube formationGO:00018381300.045
gonad developmentGO:00084061410.045
regulation of inflammatory responseGO:00507271470.045
protein localization to organelleGO:00333651850.044
regulation of rho protein signal transductionGO:0035023710.044
positive regulation of b cell activationGO:0050871490.044
cellular component assembly involved in morphogenesisGO:00109271390.044
actin filament bundle assemblyGO:0051017400.044
neuron recognitionGO:0008038250.044
positive regulation of cytokine productionGO:00018191740.044
neural precursor cell proliferationGO:00613511210.044
cellular response to external stimulusGO:0071496880.044
peptidyl lysine modificationGO:0018205770.044
positive regulation of actin filament polymerizationGO:0030838260.044
lymphocyte apoptotic processGO:0070227540.043
monocarboxylic acid metabolic processGO:00327871910.043
regulation of endocytosisGO:0030100690.043
rac protein signal transductionGO:0016601130.043
positive regulation of t cell proliferationGO:0042102520.043
divalent metal ion transportGO:00708381720.043
astrocyte differentiationGO:0048708430.043
epithelial tube formationGO:00721751300.042
regulation of reactive oxygen species metabolic processGO:2000377400.042
nucleocytoplasmic transportGO:00069131390.042
Mouse
glial cell apoptotic processGO:003434930.042
b 1a b cell differentiationGO:000233720.042
b cell apoptotic processGO:0001783190.041
blood coagulationGO:0007596760.041
regulation of lymphocyte apoptotic processGO:0070228410.041
positive regulation of cell activationGO:00508671580.041
regulation of defense responseGO:00313472330.041
negative regulation of myeloid dendritic cell activationGO:003088630.041
tissue homeostasisGO:00018941150.041
myeloid cell differentiationGO:00300992330.040
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.040
regulation of cell projection organizationGO:00313442060.040
positive regulation of lymphocyte activationGO:00512511400.040
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.040
Mouse Fly
interleukin 4 productionGO:0032633240.040

Ptpn6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.267
disease of anatomical entityDOID:700.267
hematopoietic system diseaseDOID:7400.125
primary immunodeficiency diseaseDOID:61200.063
b cell deficiencyDOID:211500.063