Mus musculus

143 known processes

Als2

amyotrophic lateral sclerosis 2 (juvenile) homolog (human)

(Aliases: mKIAA1563,Alsin,9430073A21Rik,3222402C23Rik,Als2cr6,MGC27807)

Als2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201030.096
regulation of cellular amine metabolic processGO:0033238200.062
nucleotide metabolic processGO:00091173320.059
regulation of cellular amino acid metabolic processGO:000652150.057
nucleobase containing small molecule metabolic processGO:00550863520.056
amine metabolic processGO:0009308450.056
regulation of cellular ketone metabolic processGO:0010565660.054
purine containing compound metabolic processGO:00725213110.053
cellular amine metabolic processGO:0044106440.050
embryonic organ morphogenesisGO:00485622760.049
synaptic transmissionGO:00072683290.048
positive regulation of protein phosphorylationGO:00019342420.048
Human
multicellular organismal signalingGO:0035637910.047
cellular ketone metabolic processGO:0042180840.046
regulation of transferase activityGO:00513382630.046
Human
sensory perceptionGO:00076002450.045
regulation of membrane potentialGO:00423911920.045
nucleoside phosphate metabolic processGO:00067533380.044
cellular homeostasisGO:00197252400.044
oxidation reduction processGO:00551143420.043
positive regulation of cellular amino acid metabolic processGO:004576430.043
ribonucleoside triphosphate catabolic processGO:00092031990.043
organic cyclic compound catabolic processGO:19013612950.041
purine nucleotide metabolic processGO:00061633020.040
cation homeostasisGO:00550802120.040
spermatogenesisGO:00072832840.040
ribose phosphate metabolic processGO:00196932910.039
rho protein signal transductionGO:0007266320.039
ribonucleotide metabolic processGO:00092592910.039
transmission of nerve impulseGO:0019226760.038
purine ribonucleotide metabolic processGO:00091502900.038
regulation of organelle organizationGO:00330432890.038
male gamete generationGO:00482322850.037
organonitrogen compound catabolic processGO:19015652640.037
cellular nitrogen compound catabolic processGO:00442702800.037
cellular chemical homeostasisGO:00550822150.036
neuronal action potentialGO:0019228540.036
regulation of protein kinase activityGO:00458592320.036
Human
aromatic compound catabolic processGO:00194392860.035
ribonucleoside metabolic processGO:00091192450.035
regulation of cellular catabolic processGO:00313292420.035
response to organonitrogen compoundGO:00102432460.034
ras protein signal transductionGO:0007265770.034
Rat
endomembrane system organizationGO:00102561470.033
Human
purine ribonucleoside triphosphate catabolic processGO:00092071990.033
heterocycle catabolic processGO:00467002800.033
skin developmentGO:00435882200.033
glycosyl compound metabolic processGO:19016572460.033
metal ion homeostasisGO:00550651890.033
positive regulation of cellular amine metabolic processGO:003324050.033
positive regulation of protein kinase activityGO:00458601440.033
Human
cellular ion homeostasisGO:00068731650.032
locomotory behaviorGO:00076261950.032
purine ribonucleoside metabolic processGO:00461282410.032
small gtpase mediated signal transductionGO:0007264970.032
Rat
cell type specific apoptotic processGO:00972852680.032
divalent inorganic cation homeostasisGO:00725071380.031
nucleotide catabolic processGO:00091662170.031
regulation of anatomical structure sizeGO:00900661780.031
Human
reactive oxygen species metabolic processGO:0072593840.030
skeletal system morphogenesisGO:00487052030.030
transmembrane transportGO:00550854120.030
purine ribonucleoside triphosphate metabolic processGO:00092052200.029
ribonucleotide catabolic processGO:00092612080.029
purine nucleoside metabolic processGO:00422782410.029
cellular lipid metabolic processGO:00442553230.029
purine nucleoside catabolic processGO:00061522050.029
cellular metal ion homeostasisGO:00068751510.028
positive regulation of protein modification processGO:00314012990.028
Human
cellular divalent inorganic cation homeostasisGO:00725031270.028
positive regulation of transferase activityGO:00513471670.028
Human
purine containing compound catabolic processGO:00725232130.027
multicellular organismal homeostasisGO:00488711640.027
nucleoside phosphate catabolic processGO:19012922220.026
macromolecule catabolic processGO:00090572810.026
skeletal system developmentGO:00015013560.026
purine ribonucleoside catabolic processGO:00461302050.026
nitrogen compound transportGO:00717052710.026
purine nucleoside triphosphate metabolic processGO:00091442260.026
guanosine containing compound catabolic processGO:19010691440.025
carbohydrate metabolic processGO:00059752300.025
ion transmembrane transportGO:00342203610.025
inorganic cation transmembrane transportGO:00986622070.025
organophosphate catabolic processGO:00464342320.025
purine nucleotide catabolic processGO:00061952110.025
axonogenesisGO:00074092740.025
Rat
nucleoside triphosphate metabolic processGO:00091412300.025
energy derivation by oxidation of organic compoundsGO:0015980770.024
intracellular protein transportGO:00068862040.024
cytoplasmic transportGO:00164822340.024
ribonucleoside triphosphate metabolic processGO:00091992200.024
positive regulation of mapk cascadeGO:00434101700.024
epidermis developmentGO:00085441870.024
gtp metabolic processGO:00460391440.024
guanosine containing compound metabolic processGO:19010681440.024
nucleoside metabolic processGO:00091162460.024
negative regulation of cell developmentGO:00107211690.024
peptidyl amino acid modificationGO:00181933360.024
microtubule based processGO:00070172360.024
cation transportGO:00068123990.024
response to organic cyclic compoundGO:00140701980.024
carbohydrate derivative catabolic processGO:19011362310.023
immune effector processGO:00022523210.023
purine ribonucleotide catabolic processGO:00091542080.023
female sex differentiationGO:0046660840.023
positive regulation of cellular catabolic processGO:00313311480.023
Human
regulation of cellular component biogenesisGO:00440871810.023
nucleoside triphosphate catabolic processGO:00091432050.023
synapse organizationGO:00508081250.023
regulation of kinase activityGO:00435492490.022
Human
regulation of neuron differentiationGO:00456642810.022
protein modification by small protein conjugationGO:00324461870.022
positive regulation of kinase activityGO:00336741550.022
Human
homeostasis of number of cellsGO:00488722100.022
sensory organ morphogenesisGO:00905962420.022
negative regulation of protein metabolic processGO:00512482820.022
muscle tissue developmentGO:00605373080.022
nucleocytoplasmic transportGO:00069131390.022
glycosyl compound catabolic processGO:19016582060.022
regulation of hydrolase activityGO:00513362460.022
membrane organizationGO:00610242450.022
regulation of map kinase activityGO:00434051200.022
nucleoside catabolic processGO:00091642060.021
regulation of neuron projection developmentGO:00109751690.021
action potentialGO:0001508780.021
negative regulation of cellular component organizationGO:00511291940.021
regulation of cell projection organizationGO:00313442060.021
neuron deathGO:00709971540.021
regulation of gtp catabolic processGO:00331241130.021
protein ubiquitinationGO:00165671710.021
anatomical structure homeostasisGO:00602491450.021
reactive oxygen species biosynthetic processGO:190340980.021
mapk cascadeGO:00001652810.021
regulation of nucleotide metabolic processGO:00061401690.021
organic hydroxy compound metabolic processGO:19016152030.020
endocytosisGO:00068971680.020
regulation of vesicle mediated transportGO:00606271390.020
forebrain developmentGO:00309003020.020
epithelial tube morphogenesisGO:00605623030.020
positive regulation of nucleotide metabolic processGO:00459811140.020
Human
cation transmembrane transportGO:00986552660.020
chemotaxisGO:00069352470.019
negative regulation of cellular amine metabolic processGO:003323910.019
macromolecule methylationGO:00434141200.019
stem cell differentiationGO:00488632680.019
protein modification by small protein conjugation or removalGO:00706472070.019
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.019
positive regulation of hydrolase activityGO:00513451480.019
Human
cellular macromolecule catabolic processGO:00442652060.019
regulation of mapk cascadeGO:00434082480.019
cytokine productionGO:00018163190.019
response to inorganic substanceGO:0010035960.019
leukocyte differentiationGO:00025213420.019
multicellular organism growthGO:00352641610.019
positive regulation of protein serine threonine kinase activityGO:00719021060.019
Human
positive regulation of gtpase activityGO:0043547850.019
Human
posttranscriptional regulation of gene expressionGO:00106081550.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.019
protein localization to organelleGO:00333651850.019
dna metabolic processGO:00062593030.018
sulfur compound metabolic processGO:00067901000.018
positive regulation of purine nucleotide metabolic processGO:19005441140.018
Human
learning or memoryGO:00076111480.018
regulation of neuron apoptotic processGO:00435231220.018
carbohydrate derivative biosynthetic processGO:19011371830.018
regulation of nucleoside metabolic processGO:00091181300.018
neuron apoptotic processGO:00514021420.018
inorganic ion transmembrane transportGO:00986602340.018
muscle system processGO:00030121410.018
negative regulation of neuron deathGO:1901215980.018
regulation of cell activationGO:00508652890.018
negative regulation of cellular amino acid metabolic processGO:004576300.018
striated muscle tissue developmentGO:00147062930.018
lymphocyte differentiationGO:00300982420.018
ear developmentGO:00435832000.017
regulation of secretion by cellGO:19035302490.017
gonad developmentGO:00084061410.017
cellular response to organonitrogen compoundGO:00714171450.017
germ cell developmentGO:00072811850.017
nuclear transportGO:00511691390.017
methylationGO:00322591340.017
cognitionGO:00508901490.017
regulation of nucleotide catabolic processGO:00308111220.017
tissue homeostasisGO:00018941150.017
cellular response to hormone stimulusGO:00328701500.017
regulation of purine nucleotide metabolic processGO:19005421690.017
microtubule based movementGO:0007018840.017
cell adhesionGO:00071553290.017
organelle localizationGO:00516401790.017
protein targetingGO:00066051430.017
chromatin modificationGO:00165681870.016
organonitrogen compound biosynthetic processGO:19015661920.016
regulation of protein localizationGO:00328802310.016
protein maturationGO:00516041760.016
regulation of cytokine productionGO:00018172660.016
response to oxidative stressGO:00069791230.016
regulation of hormone levelsGO:00108172110.016
muscle contractionGO:00069361010.016
positive regulation of nucleotide catabolic processGO:0030813880.016
Human
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
organelle fissionGO:00482851700.016
cellular protein complex assemblyGO:00436231160.016
negative regulation of molecular functionGO:00440922580.016
purine nucleoside triphosphate catabolic processGO:00091462030.016
mitochondrion degradationGO:000042230.016
positive regulation of organelle organizationGO:00106381280.016
epithelial cell developmentGO:00020641590.016
protein oligomerizationGO:0051259670.016
spermatid differentiationGO:00485151150.015
modification dependent macromolecule catabolic processGO:00436321330.015
cellular response to lipidGO:00713961450.015
regulation of secretionGO:00510462740.015
protein catabolic processGO:00301632210.015
axon ensheathmentGO:0008366760.015
skeletal muscle organ developmentGO:00605381630.015
regulation of system processGO:00440572000.015
response to light stimulusGO:00094161350.015
respiratory system developmentGO:00605411900.015
regulation of sequence specific dna binding transcription factor activityGO:00510901060.015
urogenital system developmentGO:00016552610.015
generation of precursor metabolites and energyGO:00060911030.015
positive regulation of nucleoside metabolic processGO:0045979910.015
Human
response to lipopolysaccharideGO:00324961280.015
positive regulation of cell deathGO:00109422240.015
ribonucleoside catabolic processGO:00424542060.015
regulation of protein serine threonine kinase activityGO:00719001570.015
Human
regulation of cell motilityGO:20001452360.015
divalent inorganic cation transportGO:00725111780.015
glycoprotein metabolic processGO:00091001160.015
cellular response to organic cyclic compoundGO:0071407870.014
hindbrain developmentGO:00309021280.014
cellular calcium ion homeostasisGO:00068741190.014
regulation of cytoskeleton organizationGO:00514931220.014
positive regulation of purine nucleotide catabolic processGO:0033123880.014
Human
negative regulation of cellular protein metabolic processGO:00322692470.014
organelle assemblyGO:00709251770.014
development of primary sexual characteristicsGO:00451371430.014
blood circulationGO:00080151950.014
peptidyl tyrosine modificationGO:00182121450.014
myeloid cell homeostasisGO:00022621140.014
covalent chromatin modificationGO:00165691630.014
myelinationGO:0042552740.014
developmental growth involved in morphogenesisGO:00605601380.014
negative regulation of phosphorus metabolic processGO:00105631840.014
small molecule biosynthetic processGO:00442831320.014
adult behaviorGO:00305341350.014
cellular response to cadmium ionGO:007127630.014
ensheathment of neuronsGO:0007272760.014
wnt signaling pathwayGO:00160551880.014
regulation of lymphocyte activationGO:00512492400.014
regulation of ras gtpase activityGO:0032318880.014
activation of mapk activityGO:0000187590.014
gland developmentGO:00487323300.014
cellular response to molecule of bacterial originGO:0071219830.014
spermatid developmentGO:00072861080.014
negative regulation of synapse assemblyGO:005196430.014
cellular response to biotic stimulusGO:0071216920.014
mitochondrion organizationGO:00070051340.014
glucose homeostasisGO:00425931280.014
neuron migrationGO:00017641220.013
developmental maturationGO:00217001930.013
establishment of protein localization to organelleGO:00725941180.013
gtp catabolic processGO:00061841430.013
renal system developmentGO:00720012250.013
regulation of reactive oxygen species metabolic processGO:2000377400.013
regulation of rho gtpase activityGO:0032319580.013
Human
negative regulation of nervous system developmentGO:00519611560.013
regulation of cell cycleGO:00517262810.013
glial cell differentiationGO:00100011310.013
hematopoietic progenitor cell differentiationGO:00022441430.013
negative regulation of phosphorylationGO:00423261660.013
regulation of feeding behaviorGO:006025930.013
positive regulation of cell developmentGO:00107202370.013
t cell activationGO:00421102890.013
inflammatory responseGO:00069542440.013
ear morphogenesisGO:00424711180.013
actin cytoskeleton organizationGO:00300362200.013
respiratory tube developmentGO:00303231670.013
peptidyl tyrosine phosphorylationGO:00181081430.013
positive regulation of nervous system developmentGO:00519622210.013
telencephalon developmentGO:00215371860.013
protein localization to nucleusGO:00345041210.013
regulation of apoptotic signaling pathwayGO:20012331970.013
positive regulation of ras gtpase activityGO:0032320650.013
Human
ossificationGO:00015032160.013
camera type eye developmentGO:00430102660.013
lateral inhibitionGO:004633110.013
metencephalon developmentGO:0022037890.013
transition metal ion homeostasisGO:0055076540.013
calcium ion homeostasisGO:00550741270.013
response to nutrient levelsGO:00316671090.013
central nervous system neuron differentiationGO:00219531620.013
response to peptideGO:19016521360.012
cell activation involved in immune responseGO:00022631260.012
lung developmentGO:00303241640.012
sequestering of metal ionGO:0051238190.012
divalent metal ion transportGO:00708381720.012
protein localization to membraneGO:00726571080.012
t cell differentiationGO:00302171740.012
regulation of actin filament based processGO:0032970990.012
leukocyte mediated immunityGO:00024431740.012
leukocyte proliferationGO:00706611720.012
limb developmentGO:00601731660.012
response to extracellular stimulusGO:00099911270.012
development of primary female sexual characteristicsGO:0046545730.012
negative regulation of neuron apoptotic processGO:0043524920.012
heart morphogenesisGO:00030071780.012
glycerolipid metabolic processGO:00464861220.012
response to acid chemicalGO:00011011110.012
dephosphorylationGO:00163111290.012
b cell activationGO:00421131610.012
regulation of purine nucleotide catabolic processGO:00331211220.012
regulation of intracellular transportGO:00323861590.012
leukocyte activation involved in immune responseGO:00023661260.012
cellular protein catabolic processGO:00442571550.012
rhythmic processGO:00485111740.012
regulation of proteolysisGO:00301621640.012
regulation of defense responseGO:00313472330.012
mitotic cell cycleGO:00002781950.012
rna processingGO:00063961050.012
regulation of actin cytoskeleton organizationGO:0032956840.012
nuclear divisionGO:00002801580.012
maintenance of locationGO:0051235890.012
anion transportGO:00068201770.012
positive regulation of cytokine productionGO:00018191740.012
response to radiationGO:00093141650.012
response to growth factorGO:00708481980.012
regulation of response to woundingGO:19030341890.012
negative regulation of intracellular signal transductionGO:19025321670.012
neural tube developmentGO:00219151600.012
negative regulation of protein modification processGO:00314001630.012
stem cell developmentGO:00488642190.012
regulation of reactive oxygen species biosynthetic processGO:190342620.012
regulation of cellular component sizeGO:00325351210.012
Human
negative regulation of growthGO:0045926990.012
lipid biosynthetic processGO:00086101790.012
apoptotic signaling pathwayGO:00971903060.012
positive regulation of lymphocyte activationGO:00512511400.012
positive regulation of neuron differentiationGO:00456661410.012
positive regulation of gtp catabolic processGO:0033126850.012
Human
organic anion transportGO:00157111370.012
regulation of endocytosisGO:0030100690.012
regulation of neuron deathGO:19012141340.012
kidney developmentGO:00018222130.012
regulation of cell migrationGO:00303342190.011
muscle cell differentiationGO:00426922610.011
g protein coupled receptor signaling pathwayGO:00071862430.011
cytoskeleton dependent intracellular transportGO:0030705500.011
carbohydrate homeostasisGO:00335001280.011
single organism cell adhesionGO:00986021560.011
myeloid cell differentiationGO:00300992330.011
sequestering of calcium ionGO:0051208180.011
innate immune responseGO:00450871570.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
cellular response to cytokine stimulusGO:00713451890.011
glycoprotein biosynthetic processGO:0009101890.011
regulation of bindingGO:00510981110.011
negative regulation of cell proliferationGO:00082852960.011
positive regulation of programmed cell deathGO:00430682180.011
protein processingGO:00164851630.011
protein importGO:00170381010.011
circulatory system processGO:00030131970.011
positive regulation of apoptotic processGO:00430652170.011
response to peptide hormoneGO:00434341270.011
dendrite developmentGO:00163581150.011
cell substrate adhesionGO:00315891300.011
canonical wnt signaling pathwayGO:00600701300.011
protein polymerizationGO:0051258570.011
engulfment of apoptotic cellGO:004365230.011
appendage morphogenesisGO:00351071490.011
negative regulation of phosphate metabolic processGO:00459361840.011
regulation of cell adhesionGO:00301551540.011
positive regulation of cell activationGO:00508671580.011
regulation of establishment of protein localizationGO:00702011810.011
multi multicellular organism processGO:00447061090.011
regulation of ion transportGO:00432692150.011
regulation of lipid metabolic processGO:00192161180.011
localization within membraneGO:005166840.011
cellular response to lipopolysaccharideGO:0071222770.011
actin filament organizationGO:00070151130.011
peripheral nervous system developmentGO:0007422530.011
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.011
compound eye developmentGO:004874910.011
adult locomotory behaviorGO:0008344910.011
peptide secretionGO:00027901140.011
iron ion homeostasisGO:0055072360.011
embryonic skeletal system developmentGO:00487061200.011
morphogenesis of embryonic epitheliumGO:00163311590.011
regulation of body fluid levelsGO:00508781620.011
mesenchymal cell developmentGO:0014031930.011
morphogenesis of a branching epitheliumGO:00611381930.011
carboxylic acid biosynthetic processGO:0046394860.011
histone modificationGO:00165701590.011
regulation of muscle system processGO:0090257800.011
regulation of ion transmembrane transportGO:00347651190.011
ubiquitin dependent protein catabolic processGO:00065111290.011
regulation of t cell activationGO:00508631700.011
chromatin organizationGO:00063252060.011
hormone secretionGO:00468791280.011
cell fate commitmentGO:00451652100.011
limb morphogenesisGO:00351081490.010
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.010
regulation of protein catabolic processGO:00421761080.010
mesenchyme developmentGO:00604851520.010
bone developmentGO:00603481200.010
heart processGO:0003015940.010
regulation of leukocyte differentiationGO:19021051590.010
cell growthGO:00160491300.010
positive regulation of cellular component biogenesisGO:0044089940.010
regulation of transmembrane transportGO:00347621280.010
reactive nitrogen species metabolic processGO:200105700.010
olfactory learningGO:000835520.010
amide transportGO:00428861380.010
establishment of vesicle localizationGO:0051650810.010
response to molecule of bacterial originGO:00022371430.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.010
sensory system developmentGO:004888030.010
negative regulation of protein phosphorylationGO:00019331260.010

Als2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.015
Human
nervous system diseaseDOID:86300.015
Human
musculoskeletal system diseaseDOID:1700.014
sensory system diseaseDOID:005015500.014
immune system diseaseDOID:291400.013
disease of metabolismDOID:001466700.012
central nervous system diseaseDOID:33100.012
Human
disease of cellular proliferationDOID:1456600.011
organ system cancerDOID:005068600.011
cancerDOID:16200.011
inherited metabolic disorderDOID:65500.011