Mus musculus

91 known processes

Sfpq

splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)

(Aliases: 5730453G22Rik,AU021830,9030402K04Rik,2810416M14Rik,PSF,REP1,1110004P21Rik,MGC101933,D4Ertd314e)

Sfpq biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna splicing via transesterification reactionsGO:0000375430.992
Human
mrna splicing via spliceosomeGO:0000398430.988
Human
rna splicingGO:0008380540.987
Human
mrna processingGO:0006397630.977
Human
regulation of mrna splicing via spliceosomeGO:0048024320.973
rna processingGO:00063961050.961
Human
mrna metabolic processGO:0016071840.944
Human
oocyte axis specificationGO:000730920.936
regulation of rna splicingGO:0043484370.934
regulation of mrna processingGO:0050684410.916
alternative mrna splicing via spliceosomeGO:0000380120.889
Human
meiotic nuclear divisionGO:00071261150.886
dna templated transcription terminationGO:000635340.816
regulation of alternative mrna splicing via spliceosomeGO:000038180.808
oocyte constructionGO:000730820.801
heterochromatin organizationGO:007082840.752
meiotic cell cycleGO:00513211220.722
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.711
Human
germ cell developmentGO:00072811850.707
regulation of mrna metabolic processGO:1903311430.705
spliceosomal complex assemblyGO:000024560.697
rna interferenceGO:001624620.686
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.672
regulation of circadian rhythmGO:0042752580.655
oogenesisGO:0048477560.638
posttranscriptional gene silencing by rnaGO:0035194100.636
organelle fissionGO:00482851700.604
negative regulation of rna splicingGO:0033119120.603
female gamete generationGO:0007292740.585
oocyte anterior posterior axis specificationGO:000731420.585
nuclear divisionGO:00002801580.579
protein complex disassemblyGO:0043241400.574
macromolecular complex disassemblyGO:0032984430.555
regulation of mrna stabilityGO:0043488230.518
circadian rhythmGO:00076231140.518
posttranscriptional regulation of gene expressionGO:00106081550.509
mitotic cell cycleGO:00002781950.504
development of primary sexual characteristicsGO:00451371430.502
intracellular mrna localizationGO:000829840.499
poly a mrna export from nucleusGO:001697340.498
microtubule cytoskeleton organizationGO:00002261570.481
regulation of organelle organizationGO:00330432890.458
ribonucleoprotein complex subunit organizationGO:0071826280.446
translationGO:0006412930.445
negative regulation of mrna processingGO:0050686120.437
mitotic cell cycle processGO:19030471590.412
regulation of meiotic cell cycleGO:0051445340.377
regionalizationGO:00030023370.371
pole plasm assemblyGO:000731520.369
cell divisionGO:00513011200.347
negative regulation of mrna splicing via spliceosomeGO:0048025120.344
mrna stabilizationGO:004825590.325
gene silencingGO:0016458380.323
negative regulation of dna templated transcription terminationGO:006056710.317
rna stabilizationGO:004348990.292
regulation of transcription by chromatin organizationGO:003440100.289
regulation of protein complex disassemblyGO:0043244280.252
gonad developmentGO:00084061410.250
regulation of cell cycleGO:00517262810.247
oocyte developmentGO:0048599330.245
rhythmic processGO:00485111740.227
cajal body organizationGO:003057610.226
termination of rna polymerase ii transcriptionGO:000636910.223
protein localization to nucleusGO:00345041210.216
positive regulation of mrna splicing via spliceosomeGO:0048026110.204
regulation of cytoskeleton organizationGO:00514931220.202
male gamete generationGO:00482322850.192
snorna metabolic processGO:001607410.190
rna catabolic processGO:0006401290.182
ribonucleoprotein complex disassemblyGO:003298830.181
negative regulation of protein metabolic processGO:00512482820.174
ossificationGO:00015032160.173
stem cell differentiationGO:00488632680.172
chromatin organizationGO:00063252060.169
rna localizationGO:0006403230.167
mitotic nuclear divisionGO:0007067480.161
gene silencing by rnaGO:0031047190.157
oocyte differentiationGO:0009994350.147
regulation of dna templated transcription terminationGO:003155410.146
establishment of organelle localizationGO:00516561220.145
receptor mediated endocytosisGO:0006898510.144
nitrogen compound transportGO:00717052710.139
aromatic compound catabolic processGO:00194392860.138
regulation of chromatin modificationGO:1903308570.137
positive regulation of mrna metabolic processGO:1903313170.135
stem cell developmentGO:00488642190.135
spermatogenesisGO:00072832840.134
myosin filament organizationGO:003103330.134
negative regulation of molecular functionGO:00440922580.134
generation of precursor metabolites and energyGO:00060911030.134
regulation of cell divisionGO:0051302760.133
regulation of synaptic growth at neuromuscular junctionGO:000858240.126
skin developmentGO:00435882200.121
cytoplasmic transportGO:00164822340.119
meiotic cell cycle processGO:1903046770.119
mrna 3 end processingGO:0031124160.119
myosin filament assemblyGO:003103420.117
positive regulation of mrna processingGO:0050685160.117
ras protein signal transductionGO:0007265770.117
regulation of chromosome organizationGO:0033044830.116
regulation of rna stabilityGO:0043487260.116
endocytosisGO:00068971680.112
nucleic acid transportGO:0050657180.111
response to heatGO:0009408270.111
covalent chromatin modificationGO:00165691630.109
maternal determination of anterior posterior axis embryoGO:000835820.104
germ cell proliferationGO:003609370.100
establishment or maintenance of cytoskeleton polarityGO:003095220.099
nuclear mrna surveillanceGO:007102810.099
nucleoside monophosphate metabolic processGO:0009123850.099
genitalia developmentGO:0048806370.098
regulation of nuclear divisionGO:0051783560.097
organic cyclic compound catabolic processGO:19013612950.096
heterochromatin assemblyGO:003150720.094
negative regulation of mrna metabolic processGO:1903312130.090
compound eye developmentGO:004874910.090
nuclear transportGO:00511691390.089
heterocycle catabolic processGO:00467002800.089
axonogenesisGO:00074092740.087
cellular nitrogen compound catabolic processGO:00442702800.085
circadian regulation of gene expressionGO:0032922480.083
multicellular organism growthGO:00352641610.081
nucleoside metabolic processGO:00091162460.080
regulation of cellular component biogenesisGO:00440871810.077
locomotory behaviorGO:00076261950.075
oxidation reduction processGO:00551143420.075
negative regulation of cellular protein metabolic processGO:00322692470.074
response to peptideGO:19016521360.073
dendrite developmentGO:00163581150.073
protein dna complex subunit organizationGO:0071824280.071
mrna splice site selectionGO:000637650.071
positive regulation of organelle organizationGO:00106381280.070
regulation of bindingGO:00510981110.069
stem cell maintenanceGO:00198271300.069
purine ribonucleoside triphosphate catabolic processGO:00092071990.068
muscle cell differentiationGO:00426922610.067
organonitrogen compound catabolic processGO:19015652640.066
anatomical structure homeostasisGO:00602491450.066
nucleoside catabolic processGO:00091642060.065
response to organonitrogen compoundGO:00102432460.065
developmental maturationGO:00217001930.064
cell maturationGO:00484691270.063
mrna transportGO:0051028130.063
mrna catabolic processGO:0006402220.061
regulation of chromatin organizationGO:1902275570.060
negative regulation of translationGO:0017148220.057
regulation of cellular amino acid metabolic processGO:000652150.056
regulation of cell cycle processGO:00105641600.056
regulation of apoptotic signaling pathwayGO:20012331970.054
Human
adult locomotory behaviorGO:0008344910.054
regulation of chromatin bindingGO:003556170.054
spermatid differentiationGO:00485151150.054
apoptotic signaling pathwayGO:00971903060.053
Human
epidermis developmentGO:00085441870.053
nucleocytoplasmic transportGO:00069131390.052
chromatin assemblyGO:0031497130.052
microtubule based processGO:00070172360.052
striated muscle myosin thick filament assemblyGO:007168810.052
cellular ketone metabolic processGO:0042180840.051
purine nucleoside metabolic processGO:00422782410.051
regulation of protein localizationGO:00328802310.050
actin cytoskeleton organizationGO:00300362200.049
energy derivation by oxidation of organic compoundsGO:0015980770.049
purine ribonucleoside monophosphate metabolic processGO:0009167800.048
cellular amino acid metabolic processGO:00065201030.048
purine nucleoside triphosphate metabolic processGO:00091442260.047
regulation of cytoplasmic transportGO:19036491120.046
positive regulation of chromosome organizationGO:2001252330.046
regulation of ras protein signal transductionGO:00465781140.046
nucleus localizationGO:0051647200.045
chromatin modificationGO:00165681870.045
negative regulation of protein complex disassemblyGO:0043242220.044
cellular chemical homeostasisGO:00550822150.044
posttranscriptional gene silencingGO:0016441100.044
rna 3 end processingGO:0031123200.043
chromatin silencing at rdnaGO:000018330.043
fertilizationGO:00095661270.042
adult behaviorGO:00305341350.042
purine nucleotide catabolic processGO:00061952110.041
maintenance of locationGO:0051235890.041
respiratory system developmentGO:00605411900.040
positive regulation of bindingGO:0051099490.040
ribonucleoside catabolic processGO:00424542060.040
organelle assemblyGO:00709251770.039
positive regulation of cell deathGO:00109422240.039
Human
regulation of nucleocytoplasmic transportGO:0046822730.039
purine nucleotide metabolic processGO:00061633020.039
multi multicellular organism processGO:00447061090.038
Fly
ribonucleoside metabolic processGO:00091192450.038
cellular protein complex disassemblyGO:0043624360.038
mrna localization resulting in posttranscriptional regulation of gene expressionGO:001060920.038
ribonucleotide metabolic processGO:00092592910.038
transcription from rna polymerase i promoterGO:0006360130.038
columnar cuboidal epithelial cell differentiationGO:0002065820.037
muscle contractionGO:00069361010.037
histone h3 deacetylationGO:007093280.037
negative regulation of cellular component organizationGO:00511291940.037
Zebrafish
carbohydrate metabolic processGO:00059752300.037
muscle tissue developmentGO:00605373080.037
chromatin assembly or disassemblyGO:0006333160.036
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.035
fatty acid derivative metabolic processGO:1901568330.035
intracellular protein transportGO:00068862040.035
purine ribonucleoside metabolic processGO:00461282410.034
purine nucleoside monophosphate metabolic processGO:0009126810.034
striated muscle tissue developmentGO:00147062930.034
regulation of actin cytoskeleton organizationGO:0032956840.034
dna packagingGO:0006323300.033
positive regulation of rna splicingGO:0033120120.033
response to lipopolysaccharideGO:00324961280.033
ribonucleoside triphosphate catabolic processGO:00092031990.032
purine nucleoside catabolic processGO:00061522050.032
protein import into nucleusGO:0006606950.032
nucleobase containing small molecule metabolic processGO:00550863520.032
nuclear importGO:0051170950.031
carbohydrate derivative catabolic processGO:19011362310.031
keratinocyte differentiationGO:0030216480.031
morphogenesis of embryonic epitheliumGO:00163311590.031
sensory perceptionGO:00076002450.031
Fly
amine metabolic processGO:0009308450.031
cellular response to insulin stimulusGO:0032869780.031
carbohydrate derivative biosynthetic processGO:19011371830.030
purine ribonucleoside monophosphate catabolic processGO:0009169570.030
protein refoldingGO:004202610.030
spermatid developmentGO:00072861080.030
nucleoside phosphate catabolic processGO:19012922220.030
epidermal cell divisionGO:001048130.029
body morphogenesisGO:0010171450.029
regulation of cellular ketone metabolic processGO:0010565660.029
lipid localizationGO:00108761260.029
positive regulation of growthGO:00459271040.028
response to peptide hormoneGO:00434341270.028
positive regulation of cell cycleGO:0045787920.028
negative regulation of gene expression epigeneticGO:0045814150.028
cell type specific apoptotic processGO:00972852680.028
monocarboxylic acid metabolic processGO:00327871910.028
chromatin silencingGO:0006342150.027
striated muscle contractionGO:0006941450.027
regulation of multi organism processGO:00439001110.027
receptor biosynthetic processGO:003280030.027
positive regulation of mapk cascadeGO:00434101700.026
dna metabolic processGO:00062593030.026
chromatin remodelingGO:0006338320.026
neural precursor cell proliferationGO:00613511210.026
protein targetingGO:00066051430.026
glycosyl compound catabolic processGO:19016582060.026
3 utr mediated mrna stabilizationGO:007093520.026
neuron migrationGO:00017641220.025
regulation of mitotic cell cycleGO:00073461260.025
cardiac muscle contractionGO:0060048320.025
regulation of cell cycle phase transitionGO:1901987770.025
nucleotide metabolic processGO:00091173320.025
regulation of homeostatic processGO:00328441820.025
skeletal system morphogenesisGO:00487052030.025
dna conformation changeGO:0071103370.024
regulation of intracellular transportGO:00323861590.024
spindle organizationGO:0007051280.024
positive regulation of apoptotic processGO:00430652170.023
Human
protein localization to organelleGO:00333651850.023
positive regulation of homeostatic processGO:0032846640.023
maternal placenta developmentGO:0001893200.023
nuclear transcribed mrna catabolic processGO:0000956160.023
mrna export from nucleusGO:0006406110.023
regulation of hormone levelsGO:00108172110.023
negative regulation of neuron apoptotic processGO:0043524920.023
purine nucleoside triphosphate catabolic processGO:00091462030.023
myeloid cell differentiationGO:00300992330.023
regulation of myeloid cell differentiationGO:0045637960.022
forebrain developmentGO:00309003020.022
negative regulation of protein modification processGO:00314001630.022
ribonucleoside monophosphate metabolic processGO:0009161800.022
cellular response to cytokine stimulusGO:00713451890.022
positive regulation of programmed cell deathGO:00430682180.022
Human
nucleosome positioningGO:001658440.022
multicellular organismal reproductive behaviorGO:0033057230.021
Fly
cardiac muscle tissue developmentGO:00487381300.021
organic hydroxy compound metabolic processGO:19016152030.021
ear developmentGO:00435832000.021
cellular response to organonitrogen compoundGO:00714171450.020
organelle localizationGO:00516401790.020
termination of rna polymerase i transcriptionGO:000636320.020
negative regulation of nervous system developmentGO:00519611560.020
Zebrafish
mapk cascadeGO:00001652810.020
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.020
Human
cardiac muscle cell differentiationGO:0055007690.020
cell substrate junction assemblyGO:0007044240.020
protein localization to chromosome centromeric regionGO:007145910.020
regulation of neuron deathGO:19012141340.019
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018410.019
developmental cell growthGO:0048588840.019
neuron projection extensionGO:1990138640.019
maintenance of protein location in nucleusGO:005145720.019
embryonic axis specificationGO:0000578300.019
mitotic cytokinesisGO:000028140.019
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.019
negative regulation of cell developmentGO:00107211690.019
Zebrafish
glycosyl compound metabolic processGO:19016572460.019
regulation of translationGO:0006417710.019
nucleotide catabolic processGO:00091662170.019
regulation of neural precursor cell proliferationGO:2000177700.019
positive regulation of cell developmentGO:00107202370.018
cellular response to dna damage stimulusGO:00069742070.018
atp dependent chromatin remodelingGO:004304490.018
mitochondrion organizationGO:00070051340.018
spliceosomal complex disassemblyGO:000039010.018
dna templated transcription elongationGO:0006354130.018
regulation of cellular amine metabolic processGO:0033238200.018
regulation of transferase activityGO:00513382630.018
blood vessel morphogenesisGO:00485142850.018
regulation of kinase activityGO:00435492490.018
nucleus organizationGO:0006997450.018
digestive tract morphogenesisGO:00485461470.018
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.018
nucleoside phosphate metabolic processGO:00067533380.018
cellular amine metabolic processGO:0044106440.017
cell junction assemblyGO:0034329520.017
response to molecule of bacterial originGO:00022371430.017
positive regulation of dna templated transcription elongationGO:003278620.017
organism emergence from protective structureGO:007168440.017
regulation of cellular response to stressGO:00801351590.017
Human Zebrafish
fatty acid metabolic processGO:00066311210.017
regulation of protein stabilityGO:0031647520.017
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.017
purine ribonucleoside triphosphate metabolic processGO:00092052200.017
positive regulation of cellular amine metabolic processGO:003324050.017
regulation of phosphatase activityGO:0010921120.017
positive regulation of intracellular estrogen receptor signaling pathwayGO:003314840.017
actin filament organizationGO:00070151130.017
rna transportGO:0050658180.017
circulatory system processGO:00030131970.017
nucleobase containing compound transportGO:0015931270.016
trabecula formationGO:0060343240.016
blastocyst hatchingGO:000183540.016
positive regulation of myeloid cell differentiationGO:0045639430.016
ribonucleoside triphosphate metabolic processGO:00091992200.016
ribose phosphate metabolic processGO:00196932910.016
carbohydrate homeostasisGO:00335001280.016
myeloid leukocyte differentiationGO:00025731190.016
peptidyl lysine modificationGO:0018205770.016
negative regulation of cell proliferationGO:00082852960.016
multicellular organismal homeostasisGO:00488711640.016
atp catabolic processGO:0006200550.016
organelle disassemblyGO:190300820.016
muscle system processGO:00030121410.016
transcription coupled nucleotide excision repairGO:000628320.016
protein stabilizationGO:0050821250.016
mitotic spindle organizationGO:0007052100.015
camera type eye developmentGO:00430102660.015
single fertilizationGO:0007338820.015
blastocyst developmentGO:0001824800.015
positive regulation of nervous system developmentGO:00519622210.015
regulation of establishment of protein localizationGO:00702011810.015
response to temperature stimulusGO:0009266550.015
purine containing compound metabolic processGO:00725213110.015
ribonucleoside monophosphate catabolic processGO:0009158570.015
histone h3 k14 acetylationGO:004415430.015
response to starvationGO:0042594650.015
pallium developmentGO:00215431200.015
synaptic transmissionGO:00072683290.015
regulation of nucleotide metabolic processGO:00061401690.015
negative regulation of intracellular signal transductionGO:19025321670.015
detection of stimulusGO:0051606840.014
regulation of microtubule cytoskeleton organizationGO:0070507370.014
nuclear exportGO:0051168340.014
response to radiationGO:00093141650.014
regulation of protein serine threonine kinase activityGO:00719001570.014
trabecula morphogenesisGO:0061383400.014
response to insulinGO:00328681000.014
cellular response to lipidGO:00713961450.014
muscle cell developmentGO:00550011330.014
localization within membraneGO:005166840.014
nucleoside triphosphate metabolic processGO:00091412300.014
modification of morphology or physiology of other organism involved in symbiotic interactionGO:0051817160.014
regulation of neuron apoptotic processGO:00435231220.014
phagocytosisGO:0006909660.013
regulation of muscle tissue developmentGO:1901861970.013
negative regulation of phosphate metabolic processGO:00459361840.013
negative regulation of neuron deathGO:1901215980.013
cell junction organizationGO:0034330770.013
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.013
organonitrogen compound biosynthetic processGO:19015661920.013
positive regulation of cell cycle processGO:0090068610.013
purine ribonucleotide metabolic processGO:00091502900.013
regulation of neuron projection developmentGO:00109751690.013
Zebrafish
negative regulation of bindingGO:0051100390.013
regulation of nucleoside metabolic processGO:00091181300.013
lipid biosynthetic processGO:00086101790.013
chemotaxisGO:00069352470.013
cellular component assembly involved in morphogenesisGO:00109271390.013
regulation of protein complex assemblyGO:0043254830.013
cardiocyte differentiationGO:0035051870.013
heart processGO:0003015940.013
epithelial cell developmentGO:00020641590.013
maternal process involved in female pregnancyGO:0060135320.013
actomyosin structure organizationGO:0031032560.013
monocarboxylic acid biosynthetic processGO:0072330610.012
organophosphate catabolic processGO:00464342320.012
positive regulation of purine nucleotide biosynthetic processGO:1900373260.012
microtubule organizing center organizationGO:0031023280.012
regulation of epidermal cell divisionGO:001048230.012
maintenance of chromatin silencingGO:000634420.012
negative regulation of organelle organizationGO:0010639900.012
cellular homeostasisGO:00197252400.012
small molecule biosynthetic processGO:00442831320.012
regulation of protein transportGO:00512231630.012
protein methylationGO:0006479810.012
atp metabolic processGO:0046034750.012
alcohol metabolic processGO:00060661160.012
attachment of spindle microtubules to kinetochoreGO:000860840.012
myotube differentiationGO:00149021050.011
glucose homeostasisGO:00425931280.011
cellular response to interferon gammaGO:0071346250.011
protein acylationGO:0043543640.011
carboxylic acid biosynthetic processGO:0046394860.011
stem cell proliferationGO:00720891170.011
inclusion body assemblyGO:007084130.011
negative regulation of neuron differentiationGO:00456651010.011
Zebrafish
cellular lipid metabolic processGO:00442553230.011
response to extracellular stimulusGO:00099911270.011
actin filament polymerizationGO:0030041440.011
organic acid biosynthetic processGO:0016053860.011
regulation of cell motilityGO:20001452360.011
neuron deathGO:00709971540.011
extracellular structure organizationGO:00430621480.011
inflammatory responseGO:00069542440.011
regulation of transcription initiation from rna polymerase ii promoterGO:006026060.011
multicellular organismal agingGO:0010259240.011
regulation of histone modificationGO:0031056560.011
cognitionGO:00508901490.011
positive regulation of nucleocytoplasmic transportGO:0046824300.010
histone modificationGO:00165701590.010
molting cycleGO:0042303900.010
negative regulation of chromatin silencingGO:003193610.010
purine ribonucleoside catabolic processGO:00461302050.010
positive regulation of translationGO:0045727190.010
positive regulation of mitotic cell cycle phase transitionGO:1901992170.010
nucleoside monophosphate catabolic processGO:0009125590.010
unsaturated fatty acid biosynthetic processGO:0006636150.010
response to oxidative stressGO:00069791230.010
Human
regulation of stem cell proliferationGO:0072091780.010
wnt signaling pathwayGO:00160551880.010
negative regulation of dephosphorylationGO:003530590.010

Sfpq disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:33100.137
neurodegenerative diseaseDOID:128900.137
nervous system diseaseDOID:86300.137
disease of anatomical entityDOID:700.137
amyotrophic lateral sclerosisDOID:33200.081
motor neuron diseaseDOID:23100.081