Mus musculus

25 known processes

Lass2

LAG1 homolog, ceramide synthase 2

(Aliases: TRH3,AI225939,0610013I17Rik)

Lass2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular lipid metabolic processGO:00442553230.197
organic hydroxy compound metabolic processGO:19016152030.133
oxidation reduction processGO:00551143420.120
metal ion homeostasisGO:00550651890.110
membrane lipid biosynthetic processGO:0046467320.105
organonitrogen compound biosynthetic processGO:19015661920.088
positive regulation of cellular amino acid metabolic processGO:004576430.085
alcohol metabolic processGO:00060661160.072
anion transportGO:00068201770.070
cellular amino acid metabolic processGO:00065201030.069
membrane organizationGO:00610242450.068
regulation of cellular amino acid metabolic processGO:000652150.066
cellular ketone metabolic processGO:0042180840.065
cellular amine metabolic processGO:0044106440.064
cytokine productionGO:00018163190.062
cation homeostasisGO:00550802120.060
leukocyte differentiationGO:00025213420.058
monocarboxylic acid metabolic processGO:00327871910.056
regulation of cytokine productionGO:00018172660.055
endomembrane system organizationGO:00102561470.054
transmembrane transportGO:00550854120.054
lipid modificationGO:0030258650.050
positive regulation of cell deathGO:00109422240.048
ion transmembrane transportGO:00342203610.048
small molecule biosynthetic processGO:00442831320.048
amine metabolic processGO:0009308450.047
cellular divalent inorganic cation homeostasisGO:00725031270.045
cellular response to lipidGO:00713961450.043
cellular homeostasisGO:00197252400.043
cellular ion homeostasisGO:00068731650.043
organic anion transportGO:00157111370.043
modification dependent macromolecule catabolic processGO:00436321330.040
sphingolipid metabolic processGO:0006665450.040
regulation of interleukin 8 productionGO:003267730.038
nitrogen compound transportGO:00717052710.038
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.037
modification dependent protein catabolic processGO:00199411330.037
apoptotic signaling pathwayGO:00971903060.037
proteasomal protein catabolic processGO:0010498980.037
steroid metabolic processGO:00082021190.037
ubiquitin dependent protein catabolic processGO:00065111290.036
regulation of cellular amine metabolic processGO:0033238200.036
organophosphate catabolic processGO:00464342320.036
cellular protein catabolic processGO:00442571550.036
protein localization to organelleGO:00333651850.035
macromolecule catabolic processGO:00090572810.035
response to oxygen radicalGO:0000305160.035
regulation of protein localizationGO:00328802310.035
regulation of sequence specific dna binding transcription factor activityGO:00510901060.035
interleukin 8 productionGO:003263740.034
striated muscle cell developmentGO:00550021250.034
cation transportGO:00068123990.034
cytoplasmic transportGO:00164822340.034
regulation of cellular catabolic processGO:00313292420.034
oocyte anterior posterior axis specificationGO:000731420.033
positive regulation of apoptotic processGO:00430652170.033
ceramide biosynthetic processGO:0046513200.033
sterol metabolic processGO:0016125580.033
positive regulation of cellular amine metabolic processGO:003324050.033
glycerophospholipid metabolic processGO:0006650710.032
cation transmembrane transportGO:00986552660.032
regulation of cellular ketone metabolic processGO:0010565660.031
muscle cell differentiationGO:00426922610.031
organonitrogen compound catabolic processGO:19015652640.031
proteolysis involved in cellular protein catabolic processGO:00516031470.031
response to acid chemicalGO:00011011110.031
lipid biosynthetic processGO:00086101790.030
regulation of cell activationGO:00508652890.030
oocyte constructionGO:000730820.030
intracellular protein transportGO:00068862040.029
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.029
response to unfolded proteinGO:0006986210.029
negative regulation of molecular functionGO:00440922580.029
axonogenesisGO:00074092740.029
cholesterol metabolic processGO:0008203560.029
response to oxidative stressGO:00069791230.028
cellular lipid catabolic processGO:0044242520.028
regulation of apoptotic signaling pathwayGO:20012331970.028
response to reactive oxygen speciesGO:0000302560.028
organic cyclic compound catabolic processGO:19013612950.028
positive regulation of programmed cell deathGO:00430682180.028
divalent inorganic cation transportGO:00725111780.028
homeostasis of number of cellsGO:00488722100.028
maintenance of locationGO:0051235890.028
carbohydrate derivative catabolic processGO:19011362310.027
t cell differentiationGO:00302171740.027
carbohydrate derivative biosynthetic processGO:19011371830.027
glycerolipid metabolic processGO:00464861220.027
positive regulation of interleukin 8 productionGO:003275720.027
protein localization to membraneGO:00726571080.027
glycerolipid biosynthetic processGO:0045017500.027
sphingolipid biosynthetic processGO:0030148260.027
regulation of multi organism processGO:00439001110.026
intrinsic apoptotic signaling pathwayGO:00971931320.026
muscle fiber developmentGO:0048747760.026
cellular metal ion homeostasisGO:00068751510.026
regulation of homeostatic processGO:00328441820.026
response to topologically incorrect proteinGO:0035966250.026
response to organic cyclic compoundGO:00140701980.026
cellular chemical homeostasisGO:00550822150.026
spermatogenesisGO:00072832840.025
t cell activationGO:00421102890.025
nucleobase containing small molecule metabolic processGO:00550863520.025
regulation of cellular response to stressGO:00801351590.025
striated muscle tissue developmentGO:00147062930.025
protein catabolic processGO:00301632210.025
cellular response to topologically incorrect proteinGO:0035967250.024
protein ubiquitinationGO:00165671710.024
divalent inorganic cation homeostasisGO:00725071380.024
response to molecule of bacterial originGO:00022371430.024
peptidyl amino acid modificationGO:00181933360.024
reactive oxygen species metabolic processGO:0072593840.024
lymphocyte differentiationGO:00300982420.024
positive regulation of cytokine productionGO:00018191740.023
immune effector processGO:00022523210.023
pole plasm assemblyGO:000731520.023
activation of immune responseGO:00022531380.023
response to inorganic substanceGO:0010035960.023
regulation of reactive oxygen species metabolic processGO:2000377400.023
cellular response to biotic stimulusGO:0071216920.023
placenta developmentGO:00018901400.023
cellular response to hormone stimulusGO:00328701500.022
regulation of lymphocyte activationGO:00512492400.022
intracellular mrna localizationGO:000829840.022
regulation of response to woundingGO:19030341890.022
negative regulation of protein metabolic processGO:00512482820.022
germ cell developmentGO:00072811850.022
regulation of mapk cascadeGO:00434082480.022
sequestering of metal ionGO:0051238190.022
cell type specific apoptotic processGO:00972852680.022
response to lipopolysaccharideGO:00324961280.022
muscle system processGO:00030121410.022
protein modification by small protein conjugation or removalGO:00706472070.022
response to light stimulusGO:00094161350.022
mapk cascadeGO:00001652810.022
regulation of lipid metabolic processGO:00192161180.021
lipid transportGO:0006869980.021
regulation of system processGO:00440572000.021
nuclear transportGO:00511691390.021
purine containing compound metabolic processGO:00725213110.021
divalent metal ion transportGO:00708381720.021
oocyte axis specificationGO:000730920.021
male gamete generationGO:00482322850.021
cellular response to superoxideGO:0071451140.021
maternal determination of anterior posterior axis embryoGO:000835820.021
cellular nitrogen compound catabolic processGO:00442702800.021
membrane lipid metabolic processGO:0006643530.020
endocytosisGO:00068971680.020
organophosphate biosynthetic processGO:00904071220.020
cellular response to lipopolysaccharideGO:0071222770.020
lateral inhibitionGO:004633110.020
calcium ion homeostasisGO:00550741270.020
regionalizationGO:00030023370.020
cofactor metabolic processGO:0051186800.020
inorganic cation transmembrane transportGO:00986622070.020
negative regulation of intracellular signal transductionGO:19025321670.020
response to endoplasmic reticulum stressGO:0034976530.020
regulation of protein transportGO:00512231630.019
positive regulation of response to woundingGO:1903036660.019
regulation of striated muscle cell differentiationGO:0051153810.019
immune response activating signal transductionGO:00027571160.019
myotube differentiationGO:00149021050.019
regulation of hormone levelsGO:00108172110.019
positive regulation of proteolysisGO:0045862850.019
regulation of endocytosisGO:0030100690.019
interleukin 8 secretionGO:007260630.019
regulation of defense responseGO:00313472330.019
cellular response to oxygen radicalGO:0071450140.019
skin developmentGO:00435882200.019
skeletal muscle organ developmentGO:00605381630.019
small gtpase mediated signal transductionGO:0007264970.019
cellular response to prostaglandin stimulusGO:007137920.019
positive regulation of reactive oxygen species metabolic processGO:2000379110.019
regulation of body fluid levelsGO:00508781620.019
adult locomotory behaviorGO:0008344910.019
sterol transmembrane transportGO:003538220.019
regulation of cellular component biogenesisGO:00440871810.019
inorganic ion transmembrane transportGO:00986602340.018
prevention of polyspermyGO:006046840.018
organophosphate ester transportGO:0015748280.018
lipid homeostasisGO:0055088630.018
alcohol biosynthetic processGO:0046165430.018
regulation of ion transportGO:00432692150.018
response to drugGO:0042493750.018
nucleotide metabolic processGO:00091173320.018
removal of superoxide radicalsGO:0019430120.018
myeloid cell homeostasisGO:00022621140.018
regulation of transferase activityGO:00513382630.018
nuclear membrane organizationGO:007176340.018
ossificationGO:00015032160.018
ceramide metabolic processGO:0006672310.018
carbohydrate metabolic processGO:00059752300.018
protein modification by small protein conjugationGO:00324461870.018
phospholipid metabolic processGO:0006644870.018
regulation of t cell activationGO:00508631700.018
response to superoxideGO:0000303160.017
fatty acid metabolic processGO:00066311210.017
regulation of hydrolase activityGO:00513362460.017
positive regulation of hydrolase activityGO:00513451480.017
ribose phosphate metabolic processGO:00196932910.017
purine ribonucleotide metabolic processGO:00091502900.017
regulation of membrane potentialGO:00423911920.017
myeloid cell differentiationGO:00300992330.017
positive regulation of homeostatic processGO:0032846640.017
regulation of proteolysisGO:00301621640.017
response to nutrient levelsGO:00316671090.017
cellular amino acid biosynthetic processGO:0008652220.017
positive regulation of protein phosphorylationGO:00019342420.017
carboxylic acid biosynthetic processGO:0046394860.017
cellular response to acid chemicalGO:0071229680.017
cytosolic calcium ion homeostasisGO:0051480700.017
sequestering of calcium ionGO:0051208180.016
nuclear importGO:0051170950.016
wound healingGO:00420601570.016
hemostasisGO:0007599780.016
regulation of plasma lipoprotein particle levelsGO:0097006230.016
positive regulation of phagocytosis engulfmentGO:006010030.016
chemotaxisGO:00069352470.016
purine ribonucleoside metabolic processGO:00461282410.016
cognitionGO:00508901490.016
transition metal ion homeostasisGO:0055076540.016
positive regulation of membrane protein ectodomain proteolysisGO:005104430.016
myoblast differentiationGO:0045445520.016
cellular calcium ion homeostasisGO:00068741190.016
defense response to bacteriumGO:00427421190.016
immune response regulating signaling pathwayGO:00027641250.016
protein importGO:00170381010.016
response to radiationGO:00093141650.016
hematopoietic progenitor cell differentiationGO:00022441430.016
negative regulation of protein phosphorylationGO:00019331260.015
neuron apoptotic processGO:00514021420.015
response to organonitrogen compoundGO:00102432460.015
regulation of ossificationGO:00302781120.015
regulation of interleukin 6 productionGO:0032675550.015
cellular response to molecule of bacterial originGO:0071219830.015
ras protein signal transductionGO:0007265770.015
heterocycle catabolic processGO:00467002800.015
l ascorbic acid metabolic processGO:001985240.015
pharynx developmentGO:006046510.015
cellular macromolecule catabolic processGO:00442652060.015
wnt signaling pathwayGO:00160551880.015
positive regulation of cholesterol storageGO:001088630.015
mitotic cell cycleGO:00002781950.015
blood coagulationGO:0007596760.015
regulation of interleukin 8 secretionGO:200048220.015
cellular response to cytokine stimulusGO:00713451890.015
organic hydroxy compound biosynthetic processGO:1901617770.015
ribonucleoside metabolic processGO:00091192450.015
positive regulation of protein modification processGO:00314012990.014
myotube cell developmentGO:0014904600.014
endoplasmic reticulum unfolded protein responseGO:0030968190.014
sphingosine metabolic processGO:000667040.014
coagulationGO:0050817780.014
negative regulation of phosphorylationGO:00423261660.014
glycosyl compound metabolic processGO:19016572460.014
regulation of skeletal muscle fiber developmentGO:0048742360.014
nucleoside metabolic processGO:00091162460.014
aromatic compound catabolic processGO:00194392860.014
cellularizationGO:000734910.014
neuron deathGO:00709971540.014
smoothened signaling pathwayGO:00072241050.014
small molecule catabolic processGO:0044282710.014
anion transmembrane transportGO:0098656710.014
muscle cell developmentGO:00550011330.014
action potentialGO:0001508780.014
embryonic placenta developmentGO:0001892980.014
epithelial cell proliferationGO:00506731740.014
regulation of protein kinase activityGO:00458592320.014
regulation of kinase activityGO:00435492490.014
cell recognitionGO:0008037830.014
negative regulation of phosphorus metabolic processGO:00105631840.014
regulation of voltage gated calcium channel activityGO:190138540.014
gland developmentGO:00487323300.014
membrane tubulationGO:009732040.013
regulation of myotube differentiationGO:0010830620.013
positive regulation of transferase activityGO:00513471670.013
purine nucleoside metabolic processGO:00422782410.013
cellular alcohol biosynthetic processGO:004410830.013
syncytium formation by plasma membrane fusionGO:0000768420.013
regulation of establishment of protein localizationGO:00702011810.013
organic acid transportGO:00158491010.013
developmental maturationGO:00217001930.013
tissue homeostasisGO:00018941150.013
adult behaviorGO:00305341350.013
cellular alcohol metabolic processGO:004410730.013
establishment or maintenance of cytoskeleton polarityGO:003095220.013
glycoprotein metabolic processGO:00091001160.013
purine nucleotide metabolic processGO:00061633020.013
cellular modified amino acid metabolic processGO:0006575630.013
hexose catabolic processGO:001932030.013
leukocyte homeostasisGO:0001776790.013
regulation of intracellular transportGO:00323861590.013
nucleocytoplasmic transportGO:00069131390.013
regulation of ion homeostasisGO:2000021640.013
positive regulation of cellular catabolic processGO:00313311480.013
plasma membrane organizationGO:0007009900.013
regulation of reproductive processGO:2000241660.013
b cell differentiationGO:0030183780.013
establishment of protein localization to organelleGO:00725941180.013
carbohydrate homeostasisGO:00335001280.013
myeloid leukocyte differentiationGO:00025731190.013
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.013
triglyceride biosynthetic processGO:0019432170.012
negative regulation of phosphate metabolic processGO:00459361840.012
extracellular structure organizationGO:00430621480.012
myosin filament assemblyGO:003103420.012
regulation of lymphocyte differentiationGO:00456191070.012
g protein coupled receptor signaling pathwayGO:00071862430.012
protein maturationGO:00516041760.012
locomotory behaviorGO:00076261950.012
positive regulation of cell activationGO:00508671580.012
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.012
anatomical structure homeostasisGO:00602491450.012
ribonucleoside catabolic processGO:00424542060.012
cellular response to oxidative stressGO:0034599760.012
regulation of secretion by cellGO:19035302490.012
positive regulation of sequestering of triglycerideGO:001089040.012
cellular transition metal ion homeostasisGO:0046916320.012
dephosphorylationGO:00163111290.012
glycosylationGO:0070085620.012
regulation of membrane protein ectodomain proteolysisGO:005104330.012
extracellular matrix organizationGO:00301981470.012
skeletal muscle fiber developmentGO:0048741580.012
posttranscriptional regulation of gene expressionGO:00106081550.012
regulation of secretionGO:00510462740.012
protein targetingGO:00066051430.012
cellular biogenic amine metabolic processGO:0006576280.012
sensory perceptionGO:00076002450.012
nadph regenerationGO:000674020.012
sterol homeostasisGO:0055092450.012
nucleoside phosphate metabolic processGO:00067533380.012
positive regulation of immune effector processGO:00026991070.012
multicellular organismal signalingGO:0035637910.012
rho protein signal transductionGO:0007266320.012
regulation of syncytium formation by plasma membrane fusionGO:0060142230.012
muscle contractionGO:00069361010.012
carboxylic acid catabolic processGO:0046395510.012
positive regulation of lymphocyte activationGO:00512511400.012
hormone secretionGO:00468791280.012
positive regulation of growthGO:00459271040.012
interleukin 6 productionGO:0032635580.012
regulation of organelle organizationGO:00330432890.012
single organism nuclear importGO:1902593950.012
cellular component assembly involved in morphogenesisGO:00109271390.012
positive regulation of cytosolic calcium ion concentrationGO:0007204650.012
regulation of peptidase activityGO:0052547960.012
positive regulation of interleukin 6 productionGO:0032755370.012
regulation of wound healingGO:0061041400.012
response to metal ionGO:0010038470.012
segmentationGO:0035282930.012
regulation of vesicle mediated transportGO:00606271390.012
organelle fissionGO:00482851700.012
cell adhesionGO:00071553290.012
regulation of leukocyte differentiationGO:19021051590.011
regulation of map kinase activityGO:00434051200.011
negative regulation of cellular protein metabolic processGO:00322692470.011
nucleoside triphosphate metabolic processGO:00091412300.011
regulation of muscle tissue developmentGO:1901861970.011
peptide transportGO:00158331330.011
nucleoside triphosphate catabolic processGO:00091432050.011
fat soluble vitamin biosynthetic processGO:004236240.011
cellular response to starvationGO:0009267570.011
cofactor transportGO:005118140.011
negative regulation of multi organism processGO:0043901680.011
nuclear divisionGO:00002801580.011
single fertilizationGO:0007338820.011
respiratory system developmentGO:00605411900.011
hair follicle developmentGO:0001942850.011
regulation of response to reactive oxygen speciesGO:190103190.011
protein secretionGO:00093061110.011
engulfment of apoptotic cellGO:004365230.011
er nucleus signaling pathwayGO:0006984270.011
positive regulation of protein transportGO:0051222930.011
negative regulation of transferase activityGO:0051348850.011
cholesterol storageGO:001087840.011
regulation of intracellular protein transportGO:0033157820.011
protein localization to vacuoleGO:007266540.011
regulation of wnt signaling pathwayGO:00301111230.011
regulation of neuron projection developmentGO:00109751690.011
negative regulation of cellular amino acid metabolic processGO:004576300.011
meiotic cell cycleGO:00513211220.011
nucleoside phosphate catabolic processGO:19012922220.011
protein processingGO:00164851630.011
detection of molecule of bacterial originGO:003249020.011
synaptic transmissionGO:00072683290.011
neuronal action potentialGO:0019228540.011
learning or memoryGO:00076111480.011
purine nucleoside triphosphate metabolic processGO:00091442260.011
sulfur compound metabolic processGO:00067901000.011
regulation of neurotransmitter levelsGO:0001505870.011
progesterone metabolic processGO:004244840.011
calcium mediated signaling using intracellular calcium sourceGO:003558430.011
striated muscle myosin thick filament assemblyGO:007168810.011
regulation of hemostasisGO:1900046280.011
lipid localizationGO:00108761260.011
positive regulation of secretionGO:00510471300.011
regulation of anatomical structure sizeGO:00900661780.011
neuromuscular processGO:0050905990.011
alpha amino acid metabolic processGO:1901605590.011
carboxylic acid transportGO:00469421000.011
peptide metabolic processGO:0006518460.011
phagocytosisGO:0006909660.010
organism emergence from protective structureGO:007168440.010
regulation of neuron apoptotic processGO:00435231220.010
protein localization to nucleusGO:00345041210.010
pigment biosynthetic processGO:0046148260.010
cell substrate adhesionGO:00315891300.010
production of molecular mediator of immune responseGO:00024401030.010
response to low density lipoprotein particleGO:005509820.010
organic hydroxy compound catabolic processGO:1901616250.010
positive regulation of cell adhesionGO:0045785800.010
blood circulationGO:00080151950.010
fat cell differentiationGO:00454441600.010
regulation of transmembrane transportGO:00347621280.010
response to tumor necrosis factorGO:0034612260.010
acylglycerol metabolic processGO:0006639550.010
organic acid catabolic processGO:0016054510.010
molting cycleGO:0042303900.010
digestionGO:0007586400.010
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.010
cell activation involved in immune responseGO:00022631260.010
negative regulation of protein modification processGO:00314001630.010
eosinophil migrationGO:007267730.010
negative regulation of apoptotic signaling pathwayGO:20012341040.010
multicellular organismal homeostasisGO:00488711640.010
glucose homeostasisGO:00425931280.010
regulation of coagulationGO:0050818310.010
regulation of protein import into nucleusGO:0042306520.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.010

Lass2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.075
inherited metabolic disorderDOID:65500.075
nervous system diseaseDOID:86300.030
disease of anatomical entityDOID:700.030
eye and adnexa diseaseDOID:149200.025
sensory system diseaseDOID:005015500.025
eye diseaseDOID:561400.025
retinal diseaseDOID:567900.025
carbohydrate metabolic disorderDOID:297800.017
immune system diseaseDOID:291400.016
lysosomal storage diseaseDOID:321100.013
central nervous system diseaseDOID:33100.013
brain diseaseDOID:93600.012
retinal degenerationDOID:846600.010