Mus musculus

269 known processes

Notch2

Notch gene homolog 2 (Drosophila)

(Aliases: N2,AI853703)

Notch2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of blood vessel endothelial cell migrationGO:004353731.000
somite specificationGO:000175741.000
venous blood vessel morphogenesisGO:004884570.999
Mouse
blood vessel endothelial cell differentiationGO:006083760.999
Mouse
regulation of transcription from rna polymerase ii promoter in response to hypoxiaGO:006141820.998
Mouse
blood vessel lumenizationGO:007255420.996
cardiac vascular smooth muscle cell developmentGO:006094830.996
Mouse
negative regulation of endothelial cell migrationGO:001059640.995
epithelial tube morphogenesisGO:00605623030.993
anagenGO:0042640130.991
Mouse
cardiac right atrium morphogenesisGO:000321330.990
Mouse
gland developmentGO:00487323300.990
Zebrafish Mouse Fly
positive regulation of transcription of notch receptor targetGO:000722140.990
Mouse
lateral inhibitionGO:004633110.989
Fly
myeloid cell differentiationGO:00300992330.988
regulation of endothelial cell chemotaxisGO:200102610.983
cell migration involved in endocardial cushion formationGO:000327330.983
Mouse
embryonic placenta developmentGO:0001892980.980
autophagic vacuole assemblyGO:0000045130.979
metanephric glomerular mesangium developmentGO:007222330.979
endothelial tube morphogenesisGO:006115420.979
negative regulation of cell migrationGO:0030336590.979
vascular smooth muscle cell differentiationGO:0035886110.977
Mouse
cardiac right ventricle formationGO:000321930.977
Mouse
arterial endothelial cell differentiationGO:006084250.975
Mouse
placenta blood vessel developmentGO:0060674310.974
cellular amino acid metabolic processGO:00065201030.974
regulation of cellular ketone metabolic processGO:0010565660.973
hair follicle developmentGO:0001942850.973
Mouse
endoplasmic reticulum calcium ion homeostasisGO:0032469110.972
renal tubule developmentGO:0061326870.971
embryonic heart tube morphogenesisGO:0003143510.968
neural tube developmentGO:00219151600.967
Mouse
regulation of neuron differentiationGO:00456642810.965
Mouse Fly
morphogenesis of an endotheliumGO:000315920.965
pulmonary valve morphogenesisGO:000318450.964
Human
appendage morphogenesisGO:00351071490.959
epithelium migrationGO:0090132630.958
Fly
dorsal aorta morphogenesisGO:003591250.957
striated muscle tissue developmentGO:00147062930.957
Mouse Fly
positive regulation of map kinase activityGO:0043406840.957
ossificationGO:00015032160.955
Mouse
regulation of cell cycleGO:00517262810.955
Human Worm Fly
regulation of cell migration involved in sprouting angiogenesisGO:009004940.954
growth involved in heart morphogenesisGO:000324140.954
Mouse
negative regulation of cell motilityGO:2000146610.953
interleukin 4 secretionGO:007260250.952
positive regulation of keratinocyte differentiationGO:004561830.949
Mouse
cation transportGO:00068123990.948
muscle tissue developmentGO:00605373080.945
Mouse Fly
regulation of somitogenesisGO:001480760.945
Mouse
columnar cuboidal epithelial cell differentiationGO:0002065820.944
Mouse Fly
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.944
respiratory system developmentGO:00605411900.944
Mouse Fly
regulation of blood vessel endothelial cell migrationGO:0043535120.941
artery developmentGO:0060840530.941
Mouse
hair cycleGO:0042633900.940
Mouse
regulation of cellular amino acid metabolic processGO:000652150.940
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.938
determination of heart left right asymmetryGO:0061371480.936
canonical wnt signaling pathway involved in heart developmentGO:006131630.930
positive regulation of cell cycleGO:0045787920.929
Fly
cell adhesionGO:00071553290.926
Fly
regulation of epidermal growth factor activated receptor activityGO:000717670.920
hematopoietic progenitor cell differentiationGO:00022441430.912
Mouse
coronary vein morphogenesisGO:000316920.908
Mouse
axonogenesisGO:00074092740.908
Mouse Fly
leukocyte differentiationGO:00025213420.907
cardiocyte differentiationGO:0035051870.903
Mouse Fly
response to peptideGO:19016521360.901
Mouse
regulation of cardiac cell fate specificationGO:200004310.901
Fly
placenta developmentGO:00018901400.901
stem cell differentiationGO:00488632680.900
Mouse Fly
regulation of cell morphogenesis involved in differentiationGO:00107691510.900
Mouse
pericardium morphogenesisGO:000334450.898
Mouse
organelle fissionGO:00482851700.895
Worm
gonad developmentGO:00084061410.892
Worm
regulation of cell migrationGO:00303342190.887
Mouse
i kappab phosphorylationGO:000725260.887
Fly
macromolecule glycosylationGO:0043413550.886
choline transportGO:001587130.886
mesenchyme developmentGO:00604851520.886
Mouse
negative regulation of epithelial cell migrationGO:001063390.886
formation of radial glial scaffoldsGO:002194340.880
myeloid leukocyte differentiationGO:00025731190.878
neuron migrationGO:00017641220.877
positive regulation of transferase activityGO:00513471670.877
mesenchymal cell differentiationGO:00487621070.876
Mouse
coronary vasculature morphogenesisGO:006097790.876
Mouse
cilium assemblyGO:0042384810.873
negative regulation of protein phosphorylationGO:00019331260.873
regulation of organelle organizationGO:00330432890.872
Worm
regulation of dna templated transcription in response to stressGO:004362090.872
Mouse
response to x rayGO:0010165110.872
epithelial cell proliferationGO:00506731740.865
Mouse Fly
epithelial cell differentiation involved in kidney developmentGO:0035850230.863
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.861
ameboidal type cell migrationGO:00016671280.860
Fly
immune effector processGO:00022523210.860
negative regulation of glial cell proliferationGO:006025340.858
Mouse
cardiac muscle tissue developmentGO:00487381300.856
Mouse
cellular response to growth factor stimulusGO:00713631970.856
positive regulation of cardiac muscle tissue growthGO:0055023150.856
Mouse
ventricular trabecula myocardium morphogenesisGO:0003222110.854
Mouse
biological phaseGO:0044848200.851
Mouse
embryonic skeletal system developmentGO:00487061200.851
transmembrane transportGO:00550854120.850
positive regulation of cell cycle g1 s phase transitionGO:190280890.850
Fly
meiotic cell cycleGO:00513211220.847
Worm
protein glycosylationGO:0006486550.845
positive regulation of protein serine threonine kinase activityGO:00719021060.845
organelle assemblyGO:00709251770.843
regulation of kinase activityGO:00435492490.841
positive regulation of apoptotic process involved in mammary gland involutionGO:006005840.841
sensory organ boundary specificationGO:000805210.838
Fly
odontogenesisGO:0042476780.838
divalent inorganic cation transportGO:00725111780.831
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361880.830
Mouse
copper ion transportGO:0006825100.828
regulation of cell motilityGO:20001452360.824
Mouse
photoreceptor cell differentiationGO:0046530520.822
Mouse Fly
immune response regulating signaling pathwayGO:00027641250.822
cytokine productionGO:00018163190.822
positive regulation of transcription from rna polymerase ii promoter in response to hypoxiaGO:006141910.822
Mouse
activation of mapkk activityGO:0000186150.820
apoptotic process involved in morphogenesisGO:0060561250.820
Mouse
ventricular septum morphogenesisGO:0060412270.819
myeloid dendritic cell differentiationGO:0043011160.816
negative regulation of cellular component organizationGO:00511291940.812
sprouting angiogenesisGO:0002040260.811
Mouse
regulation of cytokine productionGO:00018172660.810
embryonic heart tube developmentGO:0035050650.809
negative regulation of immune system processGO:00026832090.809
Mouse
appendage developmentGO:00487361660.807
epithelial to mesenchymal transition involved in endocardial cushion formationGO:0003198100.801
Mouse
positive regulation of apoptotic processGO:00430652170.801
glomerular visceral epithelial cell developmentGO:007201560.800
regulation of chemotaxisGO:0050920530.799
morphogenesis of a branching epitheliumGO:00611381930.798
Mouse
cell surface receptor signaling pathway involved in heart developmentGO:0061311150.796
Mouse
regulation of pro b cell differentiationGO:200097350.794
Mouse
axon guidanceGO:00074111410.793
Fly
kidney developmentGO:00018222130.789
autophagyGO:0006914450.788
nuclear divisionGO:00002801580.786
Worm
erythrocyte differentiationGO:0030218880.776
regulation of myeloid cell differentiationGO:0045637960.775
renal system vasculature developmentGO:0061437150.774
digestive tract morphogenesisGO:00485461470.774
Mouse Fly
cardiac muscle cell differentiationGO:0055007690.769
positive regulation of mitotic cell cycleGO:0045931410.762
Fly
clara cell differentiationGO:006048640.761
glomerular capillary formationGO:007210460.760
ovulation cycleGO:0042698590.759
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.758
melanocyte differentiationGO:0030318250.756
kidney vasculature morphogenesisGO:006143970.755
negative regulation of epidermal growth factor activated receptor activityGO:000717530.751
segment specificationGO:0007379150.747
development of primary sexual characteristicsGO:00451371430.747
Worm
regulation of epithelial cell proliferationGO:00506781410.744
Mouse
positive regulation of apoptotic signaling pathwayGO:2001235950.740
positive regulation of creb transcription factor activityGO:003279340.735
skin developmentGO:00435882200.734
Mouse
extracellular matrix organizationGO:00301981470.730
Mouse
salivary gland developmentGO:0007431370.730
regulation of heart growthGO:0060420310.729
Mouse
response to hypoxiaGO:0001666580.723
Mouse
gliogenesisGO:00420631410.720
Mouse Fly
cation homeostasisGO:00550802120.719
cell substrate adhesionGO:00315891300.718
humoral immune responseGO:0006959570.718
cardiac muscle tissue morphogenesisGO:0055008440.717
Mouse
negative regulation of cellular amine metabolic processGO:003323910.717
cellular amine metabolic processGO:0044106440.716
negative regulation of protein tyrosine kinase activityGO:006109930.715
membrane protein proteolysisGO:0033619100.715
glomerular mesangial cell developmentGO:007214430.714
Mouse
neuron projection guidanceGO:00974851410.714
Fly
embryonic limb morphogenesisGO:00303261260.714
regulation of proteolysisGO:00301621640.713
negative regulation of anoikisGO:200081120.712
neuron apoptotic processGO:00514021420.709
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.707
labyrinthine layer developmentGO:0060711490.706
labyrinthine layer blood vessel developmentGO:0060716210.705
tissue remodelingGO:00487711020.701
Human
regulation of cardioblast differentiationGO:005189030.699
Fly
beta amyloid formationGO:003420590.697
protein modification by small protein conjugation or removalGO:00706472070.697
homeostasis of number of cellsGO:00488722100.696
Fly
determination of left right symmetryGO:0007368800.696
developmental growth involved in morphogenesisGO:00605601380.693
Mouse
amine metabolic processGO:0009308450.691
regulation of cellular amine metabolic processGO:0033238200.691
proteasomal protein catabolic processGO:0010498980.689
limb developmentGO:00601731660.688
carbohydrate derivative biosynthetic processGO:19011371830.687
cardiac neural crest cell differentiation involved in heart developmentGO:006130780.686
glial cell fate determinationGO:000740330.685
Fly
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.685
immune response activating cell surface receptor signaling pathwayGO:0002429720.685
positive regulation of osteoclast differentiationGO:0045672150.684
positive regulation of cyclin dependent protein serine threonine kinase activityGO:004573760.683
myeloid leukocyte activationGO:0002274830.682
stem cell developmentGO:00488642190.681
Mouse Fly
response to oxygen levelsGO:0070482620.679
Mouse
spermatogenesisGO:00072832840.678
embryonic organ morphogenesisGO:00485622760.677
negative regulation of auditory receptor cell differentiationGO:004560820.673
heart morphogenesisGO:00030071780.673
negative regulation of neuron differentiationGO:00456651010.672
Mouse Fly
negative regulation of cell developmentGO:00107211690.671
Mouse Fly
response to symbiontGO:000960820.671
Fly
embryonic hemopoiesisGO:0035162230.667
Fly
cell type specific apoptotic processGO:00972852680.663
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042110.663
cellular response to external stimulusGO:0071496880.661
dorsal aorta developmentGO:003590760.661
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.657
regulation of neuron projection developmentGO:00109751690.656
urogenital system developmentGO:00016552610.655
lymph vessel morphogenesisGO:0036303110.654
Zebrafish
response to molecule of bacterial originGO:00022371430.652
epithelial cell developmentGO:00020641590.651
coronary vasculature developmentGO:0060976120.649
Mouse
myeloid dendritic cell activationGO:0001773250.648
interleukin 4 productionGO:0032633240.647
multi organism behaviorGO:0051705620.643
Worm
regulation of membrane potentialGO:00423911920.639
stem cell maintenanceGO:00198271300.639
Fly
memoryGO:0007613580.638
Fly
cellular response to radiationGO:0071478280.636
release of cytochrome c from mitochondriaGO:0001836230.633
defense response to other organismGO:00985421970.632
cellular amide metabolic processGO:0043603580.631
regulation of reactive oxygen species metabolic processGO:2000377400.629
actin filament organizationGO:00070151130.629
Fly
cellular ketone metabolic processGO:0042180840.629
positive regulation of epithelial cell proliferationGO:0050679680.628
Mouse
positive regulation of cell cycle processGO:0090068610.627
Fly
positive regulation of bmp signaling pathwayGO:0030513230.624
organic hydroxy compound transportGO:0015850930.618
regulation of bmp signaling pathwayGO:0030510600.617
negative regulation of neuron projection developmentGO:0010977500.617
negative regulation of fat cell differentiationGO:0045599360.615
regulation of cell cycle processGO:00105641600.612
Worm Fly
pigment cell differentiationGO:0050931270.609
atrioventricular node developmentGO:000316230.606
Mouse
synaptic transmissionGO:00072683290.605
tissue migrationGO:0090130680.603
Fly
notch signaling involved in heart developmentGO:006131450.603
Mouse
regulation of epidermal cell differentiationGO:0045604210.597
Mouse
regulation of smooth muscle cell migrationGO:001491060.596
ventricular septum developmentGO:0003281420.595
outflow tract morphogenesisGO:0003151530.594
regulation of resting membrane potentialGO:006007530.591
inner ear receptor cell fate commitmentGO:006012060.591
Mouse
myeloid cell homeostasisGO:00022621140.590
regulation of vesicle mediated transportGO:00606271390.590
Mouse
negative regulation of hematopoietic progenitor cell differentiationGO:190153340.588
Mouse
protein ubiquitinationGO:00165671710.588
positive regulation of mitotic cell cycle embryonicGO:004597720.586
lung developmentGO:00303241640.586
Mouse
cell divisionGO:00513011200.585
Mouse Worm
somitogenesisGO:0001756690.583
Mouse
activation of immune responseGO:00022531380.581
mesonephric epithelium developmentGO:0072163940.580
mitotic cell cycle processGO:19030471590.580
Fly
morphogenesis of an epithelial sheetGO:0002011270.578
skeletal muscle organ developmentGO:00605381630.576
Mouse Fly
protein modification by small protein conjugationGO:00324461870.576
formation of organ boundaryGO:001016010.575
Fly
ciliary body morphogenesisGO:006107330.575
glycosylationGO:0070085620.575
neuroblast fate determinationGO:000740010.572
Fly
molting cycleGO:0042303900.571
Mouse
response to growth factorGO:00708481980.568
embryonic appendage morphogenesisGO:00351131260.568
negative regulation of cell proliferationGO:00082852960.567
Human Mouse
digestive system developmentGO:00551232000.565
Mouse Worm Fly
morphogenesis of embryonic epitheliumGO:00163311590.561
regulation of muscle tissue developmentGO:1901861970.561
Mouse
mesangial cell differentiationGO:007200740.560
Mouse
positive regulation of mitotic cell cycle phase transitionGO:1901992170.555
Fly
mitotic cell cycleGO:00002781950.554
Fly
negative regulation of peptidyl tyrosine phosphorylationGO:0050732170.554
positive regulation of cell fate commitmentGO:001045580.551
development of primary female sexual characteristicsGO:0046545730.550
cell chemotaxisGO:0060326810.549
ion transmembrane transportGO:00342203610.549
somite developmentGO:0061053810.547
Mouse
response to radiationGO:00093141650.546
b cell activationGO:00421131610.545
cell fate determination involved in pattern specificationGO:006058210.543
Fly
regulation of cardiac muscle tissue growthGO:0055021260.542
Mouse
cognitionGO:00508901490.542
Fly
tube formationGO:00351481400.542
positive regulation of protein kinase activityGO:00458601440.538
regulation of cell activationGO:00508652890.538
regulation of protein processingGO:0070613960.537
ovarian follicle developmentGO:0001541400.535
l amino acid transportGO:0015807320.533
regulation of protein kinase activityGO:00458592320.532
glomerular mesangial cell differentiationGO:007200830.532
Mouse
cellular response to x rayGO:007148120.531
inner ear receptor cell differentiationGO:0060113610.530
Mouse
developmental programmed cell deathGO:0010623410.528
Mouse
negative regulation of protein processingGO:0010955790.528
regionalizationGO:00030023370.525
detection of chemical stimulus involved in sensory perception of tasteGO:005091230.525
regulation of mitotic cell cycleGO:00073461260.519
Fly
retinal blood vessel morphogenesisGO:006130430.518
developmental maturationGO:00217001930.517
Mouse
odontogenesis of dentin containing toothGO:0042475660.516
regulation of map kinase activityGO:00434051200.516
response to organic cyclic compoundGO:00140701980.516
regulation of cellular response to growth factor stimulusGO:0090287820.515
extrinsic apoptotic signaling pathwayGO:00971911260.514
cardiac septum morphogenesisGO:0060411460.513
Human Mouse
mesoderm developmentGO:00074981000.513
Fly
dna biosynthetic processGO:0071897220.512
proteolysis involved in cellular protein catabolic processGO:00516031470.512
neural tube formationGO:00018411080.511
dendritic cell differentiationGO:0097028260.510
response to organonitrogen compoundGO:00102432460.510
Mouse
metanephric glomerular endothelium developmentGO:007226410.508
blood vessel morphogenesisGO:00485142850.508
peptidyl serine modificationGO:0018209830.508
morphogenesis of a branching structureGO:00017632030.507
Mouse
cardiac chamber developmentGO:00032051080.506
Human Mouse
regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325660.504
Mouse
neural precursor cell proliferationGO:00613511210.500
venous blood vessel developmentGO:0060841130.498
Mouse
nephron morphogenesisGO:0072028690.496
regulation of myeloid leukocyte differentiationGO:0002761580.496
response to decreased oxygen levelsGO:0036293590.492
Mouse
striated muscle contractionGO:0006941450.491
skeletal system developmentGO:00015013560.490
Zebrafish
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.489
Mouse
positive regulation of kinase activityGO:00336741550.488
left right axis specificationGO:0070986130.488
lymphocyte proliferationGO:00466511640.486
glycerolipid metabolic processGO:00464861220.485
cardiac left ventricle morphogenesisGO:000321490.484
Mouse
photoreceptor cell developmentGO:0042461400.484
Fly
regulation of neuroblast proliferationGO:1902692270.484
regulation of coagulationGO:0050818310.482
regulation of neuron apoptotic processGO:00435231220.481
regulation of protein targetingGO:1903533610.479
inflammatory responseGO:00069542440.479
regulation of establishment of protein localizationGO:00702011810.478
carbohydrate metabolic processGO:00059752300.474
membrane protein ectodomain proteolysisGO:000650970.472
mesenchymal cell developmentGO:0014031930.472
Mouse
kidney vasculature developmentGO:0061440150.471
regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902041220.470
peptidyl amino acid modificationGO:00181933360.470
multi multicellular organism processGO:00447061090.466
Worm
divalent metal ion transportGO:00708381720.466
nephron tubule developmentGO:0072080840.465
reactive oxygen species metabolic processGO:0072593840.464
lipid biosynthetic processGO:00086101790.463
positive regulation of heart growthGO:0060421180.463
Mouse
regulation of anoikisGO:200020920.463
respiratory tube developmentGO:00303231670.462
Mouse
protein catabolic processGO:00301632210.461
keratinocyte differentiationGO:0030216480.460
Mouse
female sex differentiationGO:0046660840.459
endocardial cushion formationGO:0003272130.459
Mouse
regulation of cellular catabolic processGO:00313292420.456
innate immune responseGO:00450871570.455
negative regulation of endothelial cell differentiationGO:004560220.453
Mouse
apoptotic process involved in embryonic digit morphogenesisGO:190226330.453
Mouse
germ cell developmentGO:00072811850.452
Fly
positive regulation of smooth muscle cell migrationGO:001491140.452
extracellular structure organizationGO:00430621480.450
Mouse
metanephric glomerular mesangial cell proliferation involved in metanephros developmentGO:007226230.449
renal system developmentGO:00720012250.448
secondary heart field specificationGO:000313960.446
leukocyte proliferationGO:00706611720.443
coagulationGO:0050817780.438
cardiac muscle contractionGO:0060048320.437
positive regulation of cell deathGO:00109422240.437
blood vessel endothelial cell migrationGO:0043534230.435
retina vasculature development in camera type eyeGO:0061298170.433
cellular protein catabolic processGO:00442571550.432
nephron developmentGO:00720061090.430
positive regulation of astrocyte differentiationGO:004871180.428
Mouse
lipid homeostasisGO:0055088630.428
t cell activationGO:00421102890.427
regulation of phospholipase c activityGO:190027430.425
kidney epithelium developmentGO:00720731210.424
neural crest cell differentiationGO:0014033540.424
photoreceptor cell morphogenesisGO:000859430.424
positive regulation of cell migrationGO:00303351090.424
Mouse
neuropilin signaling pathwayGO:003818920.420
regulation of transferase activityGO:00513382630.420
negative regulation of ligase activityGO:005135230.418
neural tube patterningGO:0021532430.418
positive regulation of protein autophosphorylationGO:003195440.418
regulation of endopeptidase activityGO:0052548890.417
apoptotic process involved in developmentGO:1902742280.415
Mouse
retina vasculature morphogenesis in camera type eyeGO:0061299100.415
primary neural tube formationGO:0014020950.415
negative regulation of epidermal cell differentiationGO:004560570.414
neural crest cell migrationGO:0001755320.414
regulation of protein serine threonine kinase activityGO:00719001570.413
regulation of peptidase activityGO:0052547960.413
glomerular epithelium developmentGO:0072010110.411
cellular macromolecule catabolic processGO:00442652060.410
aortic valve morphogenesisGO:000318040.409
regulation of protein complex assemblyGO:0043254830.409
gamma delta t cell differentiationGO:0042492110.408
neuroblast differentiationGO:001401620.406
Fly
glomerulus vasculature morphogenesisGO:007210360.405
spinal cord developmentGO:0021510810.405
regulation of calcium ion dependent exocytosisGO:0017158160.404
Mouse
apoptotic process involved in mammary gland involutionGO:006005740.403
cardiac neural crest cell development involved in heart developmentGO:006130870.398
regulation of endothelial cell migrationGO:0010594220.398
cellular response to ionizing radiationGO:0071479110.396
negative regulation of protein maturationGO:1903318790.395
positive regulation of protein modification processGO:00314012990.393
mitral valve morphogenesisGO:000318340.392
wnt signaling pathwayGO:00160551880.391
Mouse
aorta developmentGO:0035904230.387
cardiac muscle cell developmentGO:0055013390.386
positive regulation of fibroblast growth factor receptor signaling pathwayGO:004574330.385
nephron epithelium developmentGO:0072009920.385
organ regenerationGO:003110020.385
regulation of apoptotic signaling pathwayGO:20012331970.384
regulation of cardiac muscle tissue developmentGO:0055024310.384
Mouse
endocytosisGO:00068971680.383
Worm
heart field specificationGO:000312860.381
cellular response to starvationGO:0009267570.381
response to steroid hormoneGO:0048545560.379
embryonic epithelial tube formationGO:00018381300.376
morphogenesis of a polarized epitheliumGO:0001738370.371
divalent inorganic cation homeostasisGO:00725071380.371
cilium morphogenesisGO:00602711020.369
neuron deathGO:00709971540.368
positive regulation of myeloid cell differentiationGO:0045639430.368
embryonic digit morphogenesisGO:0042733560.368
Mouse
glomerulus vasculature developmentGO:0072012140.368
retina development in camera type eyeGO:00600411190.367
positive regulation of dna biosynthetic processGO:200057340.366
positive regulation of protein phosphorylationGO:00019342420.366
positive regulation of myeloid leukocyte differentiationGO:0002763260.366
positive regulation of cellular amine metabolic processGO:003324050.365
cardiac conduction system developmentGO:0003161120.365
Mouse
negative regulation of calcium ion dependent exocytosisGO:004595530.364
Mouse
metanephric mesenchymal cell migrationGO:003578920.364
positive regulation of cardiac muscle cell differentiationGO:200072760.364
ras protein signal transductionGO:0007265770.363
Human
cellular response to lipidGO:00713961450.363
cell proliferation involved in outflow tract morphogenesisGO:006132540.361
heart growthGO:0060419450.361
Mouse
regulation of cell adhesionGO:00301551540.359
negative regulation of mechanoreceptor differentiationGO:004563230.359
branching involved in salivary gland morphogenesisGO:0060445260.358
jak stat cascadeGO:0007259420.358
Mouse
cellular lipid metabolic processGO:00442553230.357
cell migration involved in sprouting angiogenesisGO:000204290.355
calcium ion transportGO:00068161590.355
b cell differentiationGO:0030183780.354
positive regulation of neural precursor cell proliferationGO:2000179420.354
lung vasculature developmentGO:006042670.353
regulation of embryonic developmentGO:0045995710.353
Mouse
negative regulation of protein metabolic processGO:00512482820.353
primitive hemopoiesisGO:006021570.353
learning or memoryGO:00076111480.352
Fly
endothelial cell differentiationGO:0045446410.352
Mouse
positive regulation of reactive oxygen species metabolic processGO:2000379110.352
blood coagulationGO:0007596760.351
exocrine system developmentGO:0035272450.350
negative regulation of cell projection organizationGO:0031345560.350
regulation of nuclear divisionGO:0051783560.350
Worm
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.349
male gamete generationGO:00482322850.347
positive regulation of lymphocyte proliferationGO:0050671700.347
regulation of protein maturationGO:1903317960.347

Notch2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
heart diseaseDOID:11400.932
disease of anatomical entityDOID:700.932
Human
cardiovascular system diseaseDOID:128700.932
disease of cellular proliferationDOID:1456600.897
cancerDOID:16200.782
muscular diseaseDOID:008000000.765
musculoskeletal system diseaseDOID:1700.765
muscle tissue diseaseDOID:6600.765
disease of mental healthDOID:15000.684
cognitive disorderDOID:156100.684
myopathyDOID:42300.684
cardiomyopathyDOID:005070000.684
intrinsic cardiomyopathyDOID:006003600.684
dementiaDOID:130700.444
central nervous system diseaseDOID:33100.347
neurodegenerative diseaseDOID:128900.347
nervous system diseaseDOID:86300.347