Mus musculus

140 known processes

Socs3

suppressor of cytokine signaling 3

(Aliases: Cish3,Ef10,EF-10,Cis3,Ssi3,SSI-3)

Socs3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
t cell differentiationGO:00302171740.954
Mouse
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.953
Mouse
regulation of t cell differentiationGO:0045580830.951
Mouse
immune effector processGO:00022523210.941
Mouse
alpha beta t cell differentiation involved in immune responseGO:0002293300.934
Mouse
leukocyte differentiationGO:00025213420.931
Mouse
regulation of t helper 1 cell differentiationGO:004562570.928
Mouse
regulation of cellular amino acid metabolic processGO:000652150.896
cellular response to cytokine stimulusGO:00713451890.863
Mouse
amine metabolic processGO:0009308450.823
cellular amino acid metabolic processGO:00065201030.818
activation of janus kinase activityGO:004297620.813
Mouse
negative regulation of immune system processGO:00026832090.808
Mouse
regulation of cytokine productionGO:00018172660.796
Mouse
alpha beta t cell differentiationGO:0046632690.741
Mouse
regulation of cellular ketone metabolic processGO:0010565660.730
regulation of lymphocyte differentiationGO:00456191070.728
Mouse
adaptive immune responseGO:00022501550.721
Mouse
cellular response to biotic stimulusGO:0071216920.703
negative regulation of t cell differentiationGO:0045581230.695
Mouse
t helper 1 type immune responseGO:0042088250.693
Mouse
t cell activation involved in immune responseGO:0002286430.691
Mouse
negative regulation of protein metabolic processGO:00512482820.682
Mouse
regulation of cellular amine metabolic processGO:0033238200.680
positive regulation of cell deathGO:00109422240.678
positive regulation of t cell differentiationGO:0045582520.664
Mouse
myeloid cell differentiationGO:00300992330.664
positive regulation of cytokine productionGO:00018191740.663
cellular response to molecule of bacterial originGO:0071219830.663
regulation of inflammatory responseGO:00507271470.660
b cell mediated immunityGO:0019724710.639
response to molecule of bacterial originGO:00022371430.633
Rat
regulation of protein kinase activityGO:00458592320.633
Mouse
response to organonitrogen compoundGO:00102432460.630
response to lipopolysaccharideGO:00324961280.629
Rat
peptidyl tyrosine phosphorylationGO:00181081430.621
Mouse
peptidyl amino acid modificationGO:00181933360.599
Mouse
cd4 positive alpha beta t cell activationGO:0035710450.590
Mouse
alpha beta t cell activation involved in immune responseGO:0002287310.576
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.563
Mouse
regulation of defense responseGO:00313472330.560
regulation of hydrolase activityGO:00513362460.529
negative regulation of molecular functionGO:00440922580.526
Mouse
lymphocyte activation involved in immune responseGO:0002285930.526
Mouse
t helper cell differentiationGO:0042093280.511
Mouse
regulation of response to woundingGO:19030341890.503
negative regulation of leukocyte differentiationGO:1902106510.499
Mouse
cytokine productionGO:00018163190.498
Mouse
regulation of tyrosine phosphorylation of stat1 proteinGO:004251020.496
Mouse
positive regulation of t helper 1 cell differentiationGO:004562740.486
Mouse
cellular ketone metabolic processGO:0042180840.483
immune response activating signal transductionGO:00027571160.478
cellular response to organonitrogen compoundGO:00714171450.476
regulation of t helper 1 type immune responseGO:0002825170.469
Mouse
cytokine mediated signaling pathwayGO:00192211150.461
Mouse
regulation of antimicrobial humoral responseGO:000275930.444
positive regulation of programmed cell deathGO:00430682180.443
cellular amine metabolic processGO:0044106440.441
cellular response to amino acid stimulusGO:0071230290.430
Mouse
cd4 positive alpha beta t cell differentiationGO:0043367410.424
Mouse
interleukin 11 mediated signaling pathwayGO:003815420.413
negative regulation of intracellular signal transductionGO:19025321670.406
Mouse
cellular response to peptideGO:1901653920.398
immunoglobulin mediated immune responseGO:0016064690.395
leukocyte apoptotic processGO:0071887710.394
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.392
regulation of leukocyte differentiationGO:19021051590.391
Mouse
regulation of insulin receptor signaling pathwayGO:0046626210.378
nitrogen compound transportGO:00717052710.375
regulation of sequence specific dna binding transcription factor activityGO:00510901060.373
positive regulation of apoptotic processGO:00430652170.371
cell activation involved in immune responseGO:00022631260.360
Mouse
peptidyl tyrosine modificationGO:00182121450.357
Mouse
regulation of lymphocyte activationGO:00512492400.353
Mouse
lymphocyte differentiationGO:00300982420.353
Mouse
negative regulation of multi organism processGO:0043901680.351
positive regulation of cellular amine metabolic processGO:003324050.350
negative regulation of peptidyl tyrosine phosphorylationGO:0050732170.349
Mouse
phagocytosisGO:0006909660.338
activation of mapk activity involved in innate immune responseGO:003541920.338
carbohydrate metabolic processGO:00059752300.336
tyrosine phosphorylation of stat1 proteinGO:004250830.335
Mouse
positive regulation of peptidase activityGO:0010952490.333
defense response to virusGO:0051607680.326
regulation of t cell activationGO:00508631700.325
Mouse
peptide transportGO:00158331330.313
cellular response to interleukin 6GO:007135490.311
b cell activationGO:00421131610.308
regulation of kinase activityGO:00435492490.307
Mouse
regulation of adaptive immune responseGO:0002819900.306
Mouse
axon regenerationGO:0031103120.304
Zebrafish
interleukin 6 mediated signaling pathwayGO:007010260.303
segmentationGO:0035282930.302
t cell activationGO:00421102890.299
Mouse
cell type specific apoptotic processGO:00972852680.298
response to organic cyclic compoundGO:00140701980.292
Rat
t cell differentiation involved in immune responseGO:0002292300.288
Mouse
regulation of mapk cascadeGO:00434082480.287
type i interferon signaling pathwayGO:0060337100.287
inflammatory responseGO:00069542440.287
response to peptideGO:19016521360.284
leukocyte mediated immunityGO:00024431740.279
negative regulation of myeloid cell differentiationGO:0045638380.276
positive regulation of production of molecular mediator of immune responseGO:0002702450.276
regulation of cellular response to stressGO:00801351590.275
Zebrafish
neuron projection regenerationGO:0031102140.274
Zebrafish
regulation of transferase activityGO:00513382630.267
Mouse
regulation of tyrosine phosphorylation of stat proteinGO:0042509200.266
Mouse
positive regulation of apoptotic signaling pathwayGO:2001235950.265
cellular chemical homeostasisGO:00550822150.263
cellular calcium ion homeostasisGO:00068741190.262
regulation of peptidyl tyrosine phosphorylationGO:0050730930.257
Mouse
positive regulation of mapk cascadeGO:00434101700.257
response to radiationGO:00093141650.249
Rat
cellular response to lipidGO:00713961450.249
cellular response to type i interferonGO:0071357100.244
organonitrogen compound biosynthetic processGO:19015661920.243
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.243
regulation of leukocyte apoptotic processGO:2000106560.241
positive regulation of protein kinase activityGO:00458601440.240
Mouse
production of molecular mediator of immune responseGO:00024401030.238
regulation of jak stat cascadeGO:0046425340.234
Mouse
interleukin 8 productionGO:003263740.233
negative regulation of interleukin 8 productionGO:003271710.232
tyrosine phosphorylation of stat3 proteinGO:0042503120.225
Mouse
regulation of cell motilityGO:20001452360.224
t cell differentiation in thymusGO:0033077770.223
regulation of cd4 positive alpha beta t cell activationGO:2000514240.222
Mouse
immune response regulating signaling pathwayGO:00027641250.221
positive regulation of reactive oxygen species metabolic processGO:2000379110.218
negative regulation of t helper 2 cell differentiationGO:004562940.213
Mouse
notch signaling pathwayGO:0007219710.213
positive regulation of nucleotide metabolic processGO:00459811140.212
regulation of endopeptidase activityGO:0052548890.210
nucleocytoplasmic transportGO:00069131390.209
response to interleukin 6GO:0070741100.209
negative regulation of cellular amino acid metabolic processGO:004576300.209
leukocyte activation involved in immune responseGO:00023661260.208
Mouse
i kappab kinase nf kappab signalingGO:0007249850.207
regulation of ossificationGO:00302781120.207
positive regulation of defense responseGO:00313491240.205
negative regulation of lymphocyte differentiationGO:0045620320.205
Mouse
regulation of leukocyte mediated immunityGO:00027031040.204
regulation of osteoblast differentiationGO:0045667670.203
regulation of cd4 positive alpha beta t cell differentiationGO:0043370210.200
Mouse
regulation of type 2 immune responseGO:0002828180.198
Mouse
hindbrain developmentGO:00309021280.197
Mouse
positive regulation of growth hormone receptor signaling pathwayGO:006039930.196
negative regulation of cell proliferationGO:00082852960.196
negative regulation of cell activationGO:00508661110.194
Mouse
cellular response to lipopolysaccharideGO:0071222770.194
ossificationGO:00015032160.194
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.192
regulation of cellular catabolic processGO:00313292420.192
response to ionizing radiationGO:0010212420.191
Rat
tumor necrosis factor superfamily cytokine productionGO:0071706510.190
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.190
mapk cascadeGO:00001652810.189
cation homeostasisGO:00550802120.186
nucleotide binding oligomerization domain containing signaling pathwayGO:007042360.183
positive regulation of protein modification processGO:00314012990.183
Mouse
regulation of multi organism processGO:00439001110.180
negative regulation of alpha beta t cell activationGO:0046636180.179
Mouse
negative regulation of cytokine productionGO:0001818840.178
establishment of protein localization to organelleGO:00725941180.177
t cell apoptotic processGO:0070231390.177
lymphocyte mediated immunityGO:00024491390.176
positive regulation of antimicrobial peptide productionGO:000222510.175
immunoglobulin productionGO:0002377730.173
positive regulation of cellular amino acid metabolic processGO:004576430.171
negative regulation of lymphocyte apoptotic processGO:0070229240.169
response to interleukin 4GO:0070670230.168
regulation of peptide transportGO:0090087910.164
regionalizationGO:00030023370.163
stem cell developmentGO:00488642190.163
positive regulation of hydrolase activityGO:00513451480.163
cellular carbohydrate metabolic processGO:00442621190.162
negative regulation of cd4 positive alpha beta t cell activationGO:2000515100.162
Mouse
positive regulation of leukocyte differentiationGO:1902107860.162
Mouse
regulation of b cell mediated immunityGO:0002712370.161
positive regulation of epithelial cell proliferationGO:0050679680.161
regulation of interleukin 8 productionGO:003267730.160
gland developmentGO:00487323300.160
Mouse
positive regulation of protein phosphorylationGO:00019342420.160
Mouse
positive regulation of lymphocyte activationGO:00512511400.158
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.157
positive regulation of cell activationGO:00508671580.155
Mouse
regulation of production of molecular mediator of immune responseGO:0002700650.155
response to interleukin 12GO:007067120.153
embryonic placenta developmentGO:0001892980.153
myeloid leukocyte differentiationGO:00025731190.151
regulation of peptidase activityGO:0052547960.150
carbohydrate homeostasisGO:00335001280.149
regulation of purine nucleotide metabolic processGO:19005421690.149
negative regulation of cellular amine metabolic processGO:003323910.148
positive regulation of neuron projection regenerationGO:007057220.147
fertilizationGO:00095661270.147
cellular response to insulin stimulusGO:0032869780.147
nuclear transportGO:00511691390.146
regulation of transforming growth factor beta2 productionGO:003290920.143
cellular response to growth factor stimulusGO:00713631970.142
regulation of secretionGO:00510462740.142
Mouse
lymphocyte apoptotic processGO:0070227540.142
interferon gamma mediated signaling pathwayGO:006033350.142
fat cell differentiationGO:00454441600.141
Mouse
generation of precursor metabolites and energyGO:00060911030.140
cellular response to hormone stimulusGO:00328701500.140
cellular homeostasisGO:00197252400.138
positive regulation of kinase activityGO:00336741550.137
Mouse
toll like receptor signaling pathwayGO:0002224380.135
regulation of alpha beta t cell activationGO:0046634530.135
Mouse
lymphocyte homeostasisGO:0002260640.134
response to tumor necrosis factorGO:0034612260.133
purine containing compound metabolic processGO:00725213110.131
positive regulation of osteoblast differentiationGO:0045669340.131
regulation of erk1 and erk2 cascadeGO:0070372710.131
negative regulation of t cell activationGO:0050868650.130
Mouse
regulation of cell migrationGO:00303342190.129
interleukin 10 biosynthetic processGO:004209110.128
defense response to other organismGO:00985421970.128
response to interleukin 15GO:007067230.126
marginal zone b cell differentiationGO:000231520.125
humoral immune responseGO:0006959570.123
t cell proliferationGO:00420981200.123
regulation of protein serine threonine kinase activityGO:00719001570.122
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.122
cellular response to peptide hormone stimulusGO:0071375920.122
regulation of cysteine type endopeptidase activityGO:2000116650.121
compound eye developmentGO:004874910.121
stem cell differentiationGO:00488632680.121
endocytosisGO:00068971680.121
regulation of t helper cell differentiationGO:0045622140.120
Mouse
epithelial cell developmentGO:00020641590.119
intrinsic apoptotic signaling pathwayGO:00971931320.119
cellular response to interleukin 4GO:0071353210.118
protein modification by small protein conjugation or removalGO:00706472070.118
Mouse
type 2 immune responseGO:0042092230.117
Mouse
positive regulation of inflammatory responseGO:0050729470.116
reactive oxygen species metabolic processGO:0072593840.116
regulation of response to biotic stimulusGO:0002831380.114
regulation of myeloid cell differentiationGO:0045637960.114
positive regulation of t cell activationGO:00508701010.113
Mouse
insulin secretionGO:0030073890.112
striated muscle tissue developmentGO:00147062930.112
skin developmentGO:00435882200.111
Zebrafish
cellular glucan metabolic processGO:0006073320.111
nucleotide metabolic processGO:00091173320.110
positive regulation of cell developmentGO:00107202370.110
Mouse
purine nucleoside triphosphate metabolic processGO:00091442260.109
regulation of epithelial cell proliferationGO:00506781410.109
response to protozoanGO:0001562280.109
positive regulation of cellular catabolic processGO:00313311480.108
purine ribonucleotide metabolic processGO:00091502900.108
homeostasis of number of cellsGO:00488722100.107
protein maturationGO:00516041760.107
regulation of response to cytokine stimulusGO:0060759230.107
interleukin 27 mediated signaling pathwayGO:007010610.106
glucose homeostasisGO:00425931280.106
cytokine biosynthetic processGO:0042089680.105
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.105
negative regulation of response to cytokine stimulusGO:006076190.104
metal ion homeostasisGO:00550651890.104
regulation of apoptotic signaling pathwayGO:20012331970.103
jnk cascadeGO:0007254720.103
extracellular matrix organizationGO:00301981470.103
nucleoside phosphate metabolic processGO:00067533380.102
myeloid cell homeostasisGO:00022621140.102
chemotaxisGO:00069352470.102
negative regulation of t helper 1 cell differentiationGO:004562630.101
regulation of immunoglobulin mediated immune responseGO:0002889370.101
regulation of reactive oxygen species biosynthetic processGO:190342620.101
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:009729620.101
negative regulation of phosphorylationGO:00423261660.100
Mouse
positive regulation of cell adhesionGO:0045785800.099
negative regulation of t helper 1 type immune responseGO:000282650.099
germ cell developmentGO:00072811850.099
peptide secretionGO:00027901140.099
fasl biosynthetic processGO:004521020.098
negative regulation of nik nf kappab signalingGO:190122320.098
response to peptide hormoneGO:00434341270.098
alpha beta t cell lineage commitmentGO:000236370.097
positive regulation of nucleoside metabolic processGO:0045979910.097
peptide hormone secretionGO:00300721090.096
response to amino acidGO:0043200370.095
Mouse
regulation of antimicrobial peptide biosynthetic processGO:000280510.094
positive regulation of leukocyte apoptotic processGO:2000108210.094
ciliary neurotrophic factor mediated signaling pathwayGO:007012010.093
positive regulation of antimicrobial humoral responseGO:000276020.093
carbohydrate derivative biosynthetic processGO:19011371830.093
protein import into nucleusGO:0006606950.092
cellular metal ion homeostasisGO:00068751510.092
wound healing involved in inflammatory responseGO:000224640.091
erk1 and erk2 cascadeGO:0070371770.090
leukocyte migrationGO:00509001240.089
intracellular receptor signaling pathwayGO:0030522740.088
jak stat cascadeGO:0007259420.088
Mouse Rat
apoptotic signaling pathwayGO:00971903060.087
placenta developmentGO:00018901400.087
rhombomere formationGO:002159410.087
cd4 positive alpha beta t cell lineage commitmentGO:004337360.085
platelet derived growth factor receptor signaling pathwayGO:0048008320.085
negative regulation of cellular component organizationGO:00511291940.084
Zebrafish
positive regulation of reactive oxygen species biosynthetic processGO:190342820.084
positive regulation of transferase activityGO:00513471670.084
Mouse
chromatin modificationGO:00165681870.083
nucleoside triphosphate metabolic processGO:00091412300.083
regulation of eosinophil migrationGO:200041620.083
activation of immune responseGO:00022531380.082
leukocyte homeostasisGO:0001776790.082
regulation of t cell differentiation in thymusGO:0033081240.082
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.081
oxidation reduction processGO:00551143420.080
innate immune responseGO:00450871570.080
t helper 17 cell lineage commitmentGO:007254040.079
positive regulation of innate immune responseGO:0045089800.079
response to interferon gammaGO:0034341340.078
positive regulation of nuclear transcribed mrna poly a tail shorteningGO:006021340.078
stress activated mapk cascadeGO:0051403800.078
ribonucleoside metabolic processGO:00091192450.078
divalent inorganic cation homeostasisGO:00725071380.077
cellular response to interferon gammaGO:0071346250.077
ribonucleoside triphosphate metabolic processGO:00091992200.077
leukocyte proliferationGO:00706611720.077
negative regulation of response to woundingGO:1903035770.076
posttranscriptional regulation of gene expressionGO:00106081550.075
negative regulation of interferon gamma mediated signaling pathwayGO:006033610.075
regulation of protein targetingGO:1903533610.075
negative regulation of immune effector processGO:0002698550.075
Mouse
positive regulation of purine nucleotide metabolic processGO:19005441140.075
blood vessel morphogenesisGO:00485142850.074
negative regulation of homeostatic processGO:0032845710.073
small gtpase mediated signal transductionGO:0007264970.073
protein ubiquitinationGO:00165671710.073
Mouse
locomotory behaviorGO:00076261950.073
negative regulation of inflammatory responseGO:0050728610.073
tumor necrosis factor productionGO:0032640500.073
negative regulation of neuron apoptotic processGO:0043524920.072
energy derivation by oxidation of organic compoundsGO:0015980770.072
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126740.072
regulation of myeloid leukocyte differentiationGO:0002761580.072
syncytium formationGO:0006949430.072
gliogenesisGO:00420631410.071
t cell lineage commitmentGO:0002360130.070
polysaccharide metabolic processGO:0005976390.070
interleukin 2 mediated signaling pathwayGO:003811020.070
regulation of tyrosine phosphorylation of stat3 proteinGO:0042516100.070
Mouse
response to growth factorGO:00708481980.070
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.069
protein processingGO:00164851630.069
positive regulation of cell motilityGO:20001471160.069
ribose phosphate metabolic processGO:00196932910.069
neuron deathGO:00709971540.069
cytokine metabolic processGO:0042107710.068
positive regulation of ossificationGO:0045778470.067
chromatin organizationGO:00063252060.067
glial cell differentiationGO:00100011310.067
cellular divalent inorganic cation homeostasisGO:00725031270.067
response to nutrient levelsGO:00316671090.067
Rat
alpha beta t cell activationGO:0046631910.067
Mouse
regulation of tumor necrosis factor productionGO:0032680490.067
calcium ion homeostasisGO:00550741270.066
regulation of map kinase activityGO:00434051200.066
digestive system developmentGO:00551232000.066
hexose biosynthetic processGO:0019319390.065
monosaccharide metabolic processGO:00059961060.064
b cell differentiationGO:0030183780.064
mammary gland epithelium developmentGO:0061180650.064
myotube differentiationGO:00149021050.064
regulation of ovulationGO:006027830.063
heterocycle catabolic processGO:00467002800.063
cellular response to dna damage stimulusGO:00069742070.063
negative regulation of adaptive immune responseGO:0002820250.063
defense response to protozoanGO:0042832250.063
regulation of cell activationGO:00508652890.063
Mouse
wound healingGO:00420601570.062
lipopolysaccharide mediated signaling pathwayGO:0031663250.062
mesonephric tubule developmentGO:0072164940.062
reactive nitrogen species metabolic processGO:200105700.062
nucleobase containing small molecule metabolic processGO:00550863520.062
cognitionGO:00508901490.061
regulation of nucleotide metabolic processGO:00061401690.061
regulation of lymphocyte mediated immunityGO:0002706840.060
b cell activation involved in immune responseGO:0002312500.060
regulation of b cell activationGO:0050864810.059
innate immune response activating signal transductionGO:0002758500.059
ribonucleotide metabolic processGO:00092592910.058
negative regulation of nf kappab transcription factor activityGO:0032088150.058
purine ribonucleoside metabolic processGO:00461282410.058
regulation of activation of jak2 kinase activityGO:001053410.058
Mouse
negative regulation of glycoprotein metabolic processGO:190301930.058
regulation of notch signaling pathwayGO:0008593350.058
epithelial cell proliferationGO:00506731740.058
regulation of vesicle mediated transportGO:00606271390.058
positive regulation of eosinophil migrationGO:200041820.057
positive regulation of nervous system developmentGO:00519622210.057
Mouse
carbohydrate biosynthetic processGO:0016051740.057
isotype switchingGO:0045190360.057
regulation of bindingGO:00510981110.057
acute inflammatory responseGO:0002526410.057
positive regulation of adaptive immune responseGO:0002821610.057
Mouse
eosinophil migrationGO:007267730.057
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.057
connective tissue developmentGO:00614481790.056
reactive oxygen species biosynthetic processGO:190340980.056
regenerationGO:0031099380.056
Zebrafish Rat
regulation of glucose metabolic processGO:0010906600.056
amide transportGO:00428861380.056
chemokine productionGO:0032602340.056
protein localization to organelleGO:00333651850.055
regulation of dendritic cell cytokine productionGO:000273020.055
regulation of nucleoside metabolic processGO:00091181300.055
cellular response to organic cyclic compoundGO:0071407870.055
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126930.055
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.055
regulation of protein import into nucleusGO:0042306520.055
glycoprotein biosynthetic processGO:0009101890.055
neural tube developmentGO:00219151600.055
defense response to gram positive bacteriumGO:0050830500.054
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.054
Mouse
regulation of establishment of protein localizationGO:00702011810.054
Mouse
negative regulation of t helper cell differentiationGO:004562390.054
Mouse
t helper 1 cell differentiationGO:0045063130.054
Mouse
regulation of neuron differentiationGO:00456642810.054
Zebrafish Mouse
regulation of proteolysisGO:00301621640.054
syncytium formation by plasma membrane fusionGO:0000768420.054
symbiosis encompassing mutualism through parasitismGO:0044403830.053
regulation of innate immune responseGO:0045088910.053
protein secretionGO:00093061110.053
Mouse
jak stat cascade involved in growth hormone signaling pathwayGO:006039740.052
cation transportGO:00068123990.052
regulation of antimicrobial peptide productionGO:000278410.052
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.052
negative regulation of type 2 immune responseGO:000282980.052
Mouse
positive regulation of tumor necrosis factor productionGO:0032760300.052
regulation of homeostatic processGO:00328441820.052
regulation of lymphocyte apoptotic processGO:0070228410.051
neuron apoptotic processGO:00514021420.051
regulation of thymocyte migrationGO:200041020.051
response to extracellular stimulusGO:00099911270.051
Rat
regulation of leukocyte proliferationGO:00706631210.051
glycoprotein metabolic processGO:00091001160.051
hormone secretionGO:00468791280.051
response to insulinGO:00328681000.051
muscle cell differentiationGO:00426922610.050
regulation of neuron deathGO:19012141340.050
regulation of embryonic developmentGO:0045995710.050
male sex differentiationGO:00466611090.050
response to type i interferonGO:0034340120.050
regulation of cytokine biosynthetic processGO:0042035590.050
positive regulation of erk1 and erk2 cascadeGO:0070374470.050
negative regulation of cell adhesion mediated by integrinGO:003362920.050
glycogen metabolic processGO:0005977320.050
positive regulation of dna templated transcription elongationGO:003278620.049
cerebral cortex radially oriented cell migrationGO:0021799310.049
Mouse
cellular response to carbohydrate stimulusGO:0071322500.049
ovulation cycleGO:0042698590.049
regulation of defense response to bacteriumGO:190042430.049
digestive tract developmentGO:00485651900.049
negative regulation of ovulationGO:006028010.048
cellular response to gamma radiationGO:007148040.048
single organism nuclear importGO:1902593950.048
acylglycerol metabolic processGO:0006639550.048
cellular response to interleukin 15GO:007135020.047
nucleoside metabolic processGO:00091162460.047
antimicrobial peptide biosynthetic processGO:000277720.047
response to corticosteroidGO:0031960200.047
Rat
radial glia guided migration of purkinje cellGO:002194260.046
Mouse
regulation of protein processingGO:0070613960.046
digestive tract morphogenesisGO:00485461470.046
negative regulation of cellular protein metabolic processGO:00322692470.046
Mouse
negative regulation of lymphocyte activationGO:0051250910.046
Mouse
response to interleukin 1GO:0070555110.046
glucan metabolic processGO:0044042320.045
protein localization to nucleusGO:00345041210.045
cytoplasmic transportGO:00164822340.045
positive regulation of jnk cascadeGO:0046330460.045
gastrulationGO:00073691160.045
positive regulation of neuron apoptotic processGO:0043525250.045
skeletal muscle cell differentiationGO:0035914660.045
positive regulation of secretion by cellGO:19035321140.044
regulation of cell adhesionGO:00301551540.044

Socs3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.187
disease of cellular proliferationDOID:1456600.187
organ system cancerDOID:005068600.187
immune system cancerDOID:006008300.141
hematologic cancerDOID:253100.141
diabetes mellitusDOID:935100.084
type 2 diabetes mellitusDOID:935200.084
disease of metabolismDOID:001466700.084
carbohydrate metabolism diseaseDOID:005001300.084
glucose metabolism diseaseDOID:419400.084
acquired metabolic diseaseDOID:006015800.084
disease of anatomical entityDOID:700.076
nervous system diseaseDOID:86300.076
neuropathyDOID:87000.076
neuromuscular diseaseDOID:44000.075
charcot marie tooth diseaseDOID:1059500.075
immune system diseaseDOID:291400.062
hematopoietic system diseaseDOID:7400.062