Mus musculus

89 known processes

Sharpin

SHANK-associated RH domain interacting protein

(Aliases: SIPL1,cpdm,AW121341,RBCKL1,0610041B22Rik)

Sharpin biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of necroptotic processGO:006054690.956
Mouse
negative regulation of necrotic cell deathGO:0060547110.947
Mouse
protein modification by small protein conjugationGO:00324461870.904
Human
protein modification by small protein conjugation or removalGO:00706472070.855
Human
extrinsic apoptotic signaling pathwayGO:00971911260.825
Mouse
apoptotic signaling pathwayGO:00971903060.762
Mouse
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.728
Mouse
positive regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902110110.617
programmed necrotic cell deathGO:0097300280.610
Mouse
mitochondrion organizationGO:00070051340.540
gland developmentGO:00487323300.506
macromolecule catabolic processGO:00090572810.473
innate immune responseGO:00450871570.421
signal transduction in absence of ligandGO:0038034550.399
regulation of defense responseGO:00313472330.392
necroptotic processGO:0070266210.392
Mouse
cellular response to cytokine stimulusGO:00713451890.356
regulation of protein localizationGO:00328802310.337
Mouse
epidermis developmentGO:00085441870.327
i kappab kinase nf kappab signalingGO:0007249850.326
positive regulation of apoptotic signaling pathwayGO:2001235950.319
Mouse
protein catabolic processGO:00301632210.305
chromatin organizationGO:00063252060.304
mitochondrial outer membrane permeabilization involved in programmed cell deathGO:1902686110.296
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.294
pigmentationGO:0043473710.278
respiratory tube developmentGO:00303231670.261
regulation of response to woundingGO:19030341890.260
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.259
cytokine biosynthetic processGO:0042089680.239
regulation of cytokine productionGO:00018172660.234
epithelial tube morphogenesisGO:00605623030.226
skin developmentGO:00435882200.223
mitochondrial membrane organizationGO:0007006260.219
regulation of necroptotic processGO:0060544100.209
Mouse
regulation of interleukin 6 productionGO:0032675550.200
regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902108140.199
skeletal system developmentGO:00015013560.196
embryonic skeletal system developmentGO:00487061200.195
cellular ketone metabolic processGO:0042180840.194
compound eye developmentGO:004874910.193
ear developmentGO:00435832000.191
negative regulation of molecular functionGO:00440922580.188
digestive system developmentGO:00551232000.180
regulation of cytokine biosynthetic processGO:0042035590.179
embryonic organ morphogenesisGO:00485622760.179
negative regulation of apoptotic signaling pathwayGO:20012341040.178
sensory perceptionGO:00076002450.176
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.173
amine metabolic processGO:0009308450.171
respiratory system developmentGO:00605411900.170
regulation of mitochondrial membrane permeabilityGO:0046902170.162
protein polyubiquitinationGO:0000209330.160
Human
positive regulation of innate immune responseGO:0045089800.159
negative regulation of defense responseGO:0031348770.158
t cell proliferationGO:00420981200.157
protein localization to organelleGO:00333651850.152
Mouse
mitotic cell cycle processGO:19030471590.146
chromatin modificationGO:00165681870.146
cytokine metabolic processGO:0042107710.141
myeloid leukocyte differentiationGO:00025731190.141
cell fate commitmentGO:00451652100.141
lung developmentGO:00303241640.140
post embryonic organ developmentGO:0048569170.140
covalent chromatin modificationGO:00165691630.138
positive regulation of mitochondrial membrane permeabilityGO:0035794120.137
regulation of cellular amine metabolic processGO:0033238200.137
dephosphorylationGO:00163111290.137
activation of immune responseGO:00022531380.136
regulation of sequence specific dna binding transcription factor activityGO:00510901060.136
regulation of cellular component biogenesisGO:00440871810.135
regulation of apoptotic signaling pathwayGO:20012331970.133
Mouse
cellular macromolecule catabolic processGO:00442652060.133
positive regulation of secondary heart field cardioblast proliferationGO:007251340.129
response to light stimulusGO:00094161350.128
negative regulation of cell fate specificationGO:000999640.123
digestive tract morphogenesisGO:00485461470.122
apoptotic mitochondrial changesGO:0008637480.120
protein localization to nucleusGO:00345041210.119
Mouse
immune response activating signal transductionGO:00027571160.119
regulation of necrotic cell deathGO:0010939130.118
Mouse
regulation of cytoplasmic transportGO:19036491120.118
Mouse
embryonic skeletal system morphogenesisGO:0048704910.118
activation of innate immune responseGO:0002218560.115
inner ear morphogenesisGO:00424721010.115
positive regulation of notch signaling pathwayGO:0045747180.113
regulation of intracellular protein transportGO:0033157820.112
Mouse
kidney developmentGO:00018222130.111
pigment cell differentiationGO:0050931270.111
regulation of organ morphogenesisGO:20000271440.108
gastrulationGO:00073691160.107
epithelial cell proliferationGO:00506731740.107
cellular response to lipopolysaccharideGO:0071222770.107
developmental pigmentationGO:0048066400.106
cellular response to tumor necrosis factorGO:0071356210.105
cellular protein catabolic processGO:00442571550.104
mapk cascadeGO:00001652810.104
cytokine productionGO:00018163190.104
response to tumor necrosis factorGO:0034612260.099
negative regulation of cytokine productionGO:0001818840.099
renal system developmentGO:00720012250.099
positive regulation of production of molecular mediator of immune responseGO:0002702450.098
negative regulation of response to woundingGO:1903035770.097
positive regulation of defense responseGO:00313491240.094
proteolysis involved in cellular protein catabolic processGO:00516031470.092
regulation of protein import into nucleusGO:0042306520.092
Mouse
cellular amine metabolic processGO:0044106440.092
intracellular protein transportGO:00068862040.091
Mouse
male sex differentiationGO:00466611090.091
sensory perception of mechanical stimulusGO:00509541070.090
regulation of epithelial cell proliferationGO:00506781410.090
male gamete generationGO:00482322850.089
organelle localizationGO:00516401790.087
hepaticobiliary system developmentGO:0061008670.087
urogenital system developmentGO:00016552610.086
nucleocytoplasmic transportGO:00069131390.086
Mouse
immune response regulating signaling pathwayGO:00027641250.085
regulation of kinase activityGO:00435492490.084
ear morphogenesisGO:00424711180.082
middle ear morphogenesisGO:0042474230.080
regulation of cellular amino acid metabolic processGO:000652150.079
skeletal system morphogenesisGO:00487052030.078
membrane organizationGO:00610242450.077
morphogenesis of a branching epitheliumGO:00611381930.076
muscle tissue developmentGO:00605373080.076
single organism nuclear importGO:1902593950.075
Mouse
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.075
striated muscle tissue developmentGO:00147062930.074
spermatogenesisGO:00072832840.074
establishment of organelle localizationGO:00516561220.074
regulation of establishment of protein localizationGO:00702011810.074
Mouse
leukocyte proliferationGO:00706611720.073
mitochondrial transportGO:0006839360.072
negative regulation of intracellular signal transductionGO:19025321670.072
regulation of membrane permeabilityGO:0090559180.072
positive regulation of cell deathGO:00109422240.071
Mouse
nuclear importGO:0051170950.071
Mouse
cytokine mediated signaling pathwayGO:00192211150.071
sensory organ morphogenesisGO:00905962420.070
positive regulation of lymphocyte activationGO:00512511400.069
necrotic cell deathGO:0070265300.068
Mouse
male gonad developmentGO:0008584880.068
microtubule based processGO:00070172360.067
heart morphogenesisGO:00030071780.067
regulation of cellular ketone metabolic processGO:0010565660.066
cellular component disassembly involved in execution phase of apoptosisGO:000692190.064
response to radiationGO:00093141650.063
regulation of map kinase activityGO:00434051200.062
cellular response to lipidGO:00713961450.062
positive regulation of protein localization to nucleusGO:1900182300.062
Mouse
digestive tract developmentGO:00485651900.061
regulation of production of molecular mediator of immune responseGO:0002700650.061
regulation of multi organism processGO:00439001110.061
metanephros developmentGO:0001656790.060
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.059
protein sumoylationGO:0016925140.059
peptide transportGO:00158331330.057
Mouse
immune effector processGO:00022523210.056
cellular amino acid metabolic processGO:00065201030.055
negative regulation of cellular amino acid metabolic processGO:004576300.055
positive regulation of cytokine biosynthetic processGO:0042108400.054
cellular response to molecule of bacterial originGO:0071219830.054
immunoglobulin mediated immune responseGO:0016064690.054
liver developmentGO:0001889660.054
leukocyte differentiationGO:00025213420.054
response to acid chemicalGO:00011011110.054
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.054
regulation of t cell activationGO:00508631700.053
regulation of proteolysisGO:00301621640.053
lymphocyte differentiationGO:00300982420.053
interleukin 6 productionGO:0032635580.053
regulation of lymphocyte proliferationGO:00506701170.053
sensory perception of soundGO:0007605970.052
regulation of transcription factor import into nucleusGO:0042990240.052
Mouse
protein import into nucleusGO:0006606950.051
Mouse
positive regulation of apoptotic processGO:00430652170.051
Mouse
t cell activationGO:00421102890.051
neuron projection guidanceGO:00974851410.051
lung epithelial cell differentiationGO:0060487290.050
reactive oxygen species metabolic processGO:0072593840.050
regulation of nucleocytoplasmic transportGO:0046822730.050
Mouse
regulation of secretionGO:00510462740.050
regulation of secretion by cellGO:19035302490.050
lung cell differentiationGO:0060479300.050
amide transportGO:00428861380.048
Mouse
g protein coupled receptor signaling pathwayGO:00071862430.048
regulation of protein targetingGO:1903533610.048
Mouse
lymphocyte mediated immunityGO:00024491390.048
organonitrogen compound biosynthetic processGO:19015661920.048
positive regulation of cytokine productionGO:00018191740.048
regionalizationGO:00030023370.047
positive regulation of immune effector processGO:00026991070.047
histone modificationGO:00165701590.047
regulation of innate immune responseGO:0045088910.047
nephron epithelium morphogenesisGO:0072088680.047
regulation of neuron differentiationGO:00456642810.046
execution phase of apoptosisGO:0097194190.046
mitochondrial outer membrane permeabilizationGO:0097345100.046
germinal center formationGO:0002467160.046
lymphocyte activation involved in immune responseGO:0002285930.046
regulation of reactive oxygen species biosynthetic processGO:190342620.046
myeloid cell differentiationGO:00300992330.046
regulation of cellular response to stressGO:00801351590.045
positive regulation of interleukin 12 productionGO:0032735210.045
regulation of notch signaling pathwayGO:0008593350.045
ras protein signal transductionGO:0007265770.044
negative regulation of immune system processGO:00026832090.044
production of molecular mediator of immune responseGO:00024401030.044
positive regulation of cell activationGO:00508671580.043
regulation of reactive oxygen species metabolic processGO:2000377400.043
heart formationGO:0060914160.043
regulation of protein transportGO:00512231630.043
Mouse
positive regulation of programmed cell deathGO:00430682180.042
Mouse
regulation of response to cytokine stimulusGO:0060759230.042
negative regulation of nf kappab transcription factor activityGO:0032088150.042
negative regulation of blood vessel endothelial cell migrationGO:004353730.042
antimicrobial peptide productionGO:000277520.042
response to oxidative stressGO:00069791230.041
regulation of inflammatory responseGO:00507271470.041
regulation of intracellular transportGO:00323861590.041
Mouse
regulation of organelle organizationGO:00330432890.041
nephron developmentGO:00720061090.041
iron sulfur cluster assemblyGO:001622630.040
negative regulation of protein metabolic processGO:00512482820.040
pattern recognition receptor signaling pathwayGO:0002221470.040
negative regulation of cellular amine metabolic processGO:003323910.040
maintenance of locationGO:0051235890.040
activation of nf kappab inducing kinase activityGO:000725040.040
adaptive immune responseGO:00022501550.039
axon guidanceGO:00074111410.039
mitotic cell cycleGO:00002781950.039
gonad developmentGO:00084061410.039
purine containing compound metabolic processGO:00725213110.039
hair follicle developmentGO:0001942850.039
cell type specific apoptotic processGO:00972852680.039
positive regulation of macroautophagyGO:001623930.038
ubiquitin dependent protein catabolic processGO:00065111290.038
nephron epithelium developmentGO:0072009920.038
b cell differentiationGO:0030183780.038
inflammatory responseGO:00069542440.037
axonogenesisGO:00074092740.037
peptidyl tyrosine dephosphorylationGO:0035335230.037
blood vessel morphogenesisGO:00485142850.037
regulation of cysteine type endopeptidase activityGO:2000116650.037
b cell activationGO:00421131610.037
positive regulation of t cell proliferationGO:0042102520.037
regulation of transferase activityGO:00513382630.037
negative regulation of signal transduction in absence of ligandGO:1901099160.036
cytoplasmic transportGO:00164822340.036
Mouse
innate immune response activating signal transductionGO:0002758500.035
transmembrane transportGO:00550854120.035
neuron deathGO:00709971540.035
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.035
positive regulation of protein modification processGO:00314012990.035
regulation of neuron projection developmentGO:00109751690.035
response to lipopolysaccharideGO:00324961280.034
cellular response to dna damage stimulusGO:00069742070.034
regulation of cell motilityGO:20001452360.034
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.034
pharyngeal system developmentGO:0060037170.034
antigen receptor mediated signaling pathwayGO:0050851640.034
positive regulation of cellular amino acid metabolic processGO:004576430.034
peptidyl amino acid modificationGO:00181933360.033
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.033
Mouse
regulation of interleukin 8 productionGO:003267730.033
camera type eye developmentGO:00430102660.033
salivary gland developmentGO:0007431370.033
lymphocyte proliferationGO:00466511640.033
protein processingGO:00164851630.032
regulation of engulfment of apoptotic cellGO:190107420.032
positive regulation of epithelial cell proliferationGO:0050679680.032
regulation of protein kinase activityGO:00458592320.032
positive regulation of protein phosphorylationGO:00019342420.032
positive regulation of protein transportGO:0051222930.032
Mouse
regulation of cell cycleGO:00517262810.032
proteasomal protein catabolic processGO:0010498980.032
regulation of lymphocyte mediated immunityGO:0002706840.032
establishment or maintenance of apical basal cell polarityGO:0035088210.031
kidney epithelium developmentGO:00720731210.031
modification dependent protein catabolic processGO:00199411330.031
lipid localizationGO:00108761260.031
response to molecule of bacterial originGO:00022371430.031
positive regulation of reactive oxygen species biosynthetic processGO:190342820.031
morphogenesis of a branching structureGO:00017632030.031
apoptotic nuclear changesGO:003026290.031
chemotaxisGO:00069352470.031
myeloid leukocyte activationGO:0002274830.031
immune response regulating cell surface receptor signaling pathwayGO:0002768800.030
positive regulation of cellular amine metabolic processGO:003324050.030
t cell differentiationGO:00302171740.030
regulation of leukocyte proliferationGO:00706631210.030
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.030
negative regulation of inflammatory responseGO:0050728610.030
negative regulation of protein modification processGO:00314001630.030
positive regulation of nf kappab transcription factor activityGO:0051092300.030
negative regulation of mapk cascadeGO:0043409650.030
steroid metabolic processGO:00082021190.030
skin morphogenesisGO:0043589380.029
lung epithelium developmentGO:0060428370.029
cochlea developmentGO:0090102350.029
cochlea morphogenesisGO:0090103220.029
dna metabolic processGO:00062593030.029
regulation of leukocyte mediated immunityGO:00027031040.029
myeloid dendritic cell activationGO:0001773250.029
protein targetingGO:00066051430.029
Mouse
cellular response to nitric oxideGO:007173240.029
intra golgi vesicle mediated transportGO:000689110.028
organelle fissionGO:00482851700.028
molting cycleGO:0042303900.028
epidermis morphogenesisGO:0048730330.028
cytokine production involved in immune responseGO:0002367340.028
dendrite developmentGO:00163581150.028
negative regulation of phosphorylationGO:00423261660.028
cellular response to transforming growth factor beta stimulusGO:0071560880.028
negative regulation of endothelial cell migrationGO:001059640.027
antimicrobial peptide biosynthetic processGO:000277720.027
glycosyl compound metabolic processGO:19016572460.027
cell fate specificationGO:0001708720.027
reactive nitrogen species metabolic processGO:200105700.027
cd4 positive alpha beta t cell activationGO:0035710450.027
spleen developmentGO:0048536390.027
alcohol metabolic processGO:00060661160.026
cognitionGO:00508901490.026
regulation of interleukin 2 productionGO:0032663280.026
tissue homeostasisGO:00018941150.026
regulation of ion transportGO:00432692150.026
cellular ion homeostasisGO:00068731650.026
positive regulation of leukocyte proliferationGO:0070665730.026
mesoderm formationGO:0001707620.026
carbohydrate derivative biosynthetic processGO:19011371830.026
leukocyte activation involved in immune responseGO:00023661260.025
positive regulation of protein import into nucleusGO:0042307260.025
Mouse
golgi to endosome transportGO:000689530.025
negative regulation of protein transportGO:0051224460.025
regulation of t cell proliferationGO:0042129920.025
protein importGO:00170381010.025
Mouse
keratinocyte proliferationGO:0043616210.025
epithelial tube formationGO:00721751300.025
regulation of homeostatic processGO:00328441820.025
establishment of protein localization to organelleGO:00725941180.025
Mouse
establishment or maintenance of bipolar cell polarityGO:0061245210.025
cellular divalent inorganic cation homeostasisGO:00725031270.025
regulation of lymphocyte activationGO:00512492400.025
positive regulation of cell developmentGO:00107202370.024
cellular response to biotic stimulusGO:0071216920.024
aorta developmentGO:0035904230.024
microtubule cytoskeleton organizationGO:00002261570.024
outflow tract morphogenesisGO:0003151530.024
engulfment of apoptotic cellGO:004365230.024
development of primary male sexual characteristicsGO:0046546880.024
negative regulation of cytokine biosynthetic processGO:0042036130.024
hair cycleGO:0042633900.024
response to growth factorGO:00708481980.023
protein deacetylationGO:0006476320.023
embryonic epithelial tube formationGO:00018381300.023
purine ribonucleotide metabolic processGO:00091502900.023
t helper 1 type immune responseGO:0042088250.023
tube formationGO:00351481400.023
negative regulation of cellular protein metabolic processGO:00322692470.023
somatic diversification of immunoglobulinsGO:0016445430.023
negative regulation of protein processingGO:0010955790.023
hematopoietic progenitor cell differentiationGO:00022441430.023
response to retinoic acidGO:0032526560.023
nucleotide metabolic processGO:00091173320.023
regulation of adaptive immune responseGO:0002819900.022
cation transportGO:00068123990.022
aromatic compound catabolic processGO:00194392860.022
positive regulation of protein serine threonine kinase activityGO:00719021060.022
positive regulation of lymphocyte mediated immunityGO:0002708620.022
placenta developmentGO:00018901400.022
positive regulation of lymphocyte proliferationGO:0050671700.022
nucleobase containing small molecule metabolic processGO:00550863520.022
osteoclast differentiationGO:0030316620.022
nuclear transportGO:00511691390.022
Mouse
protein maturationGO:00516041760.022
ureteric bud morphogenesisGO:0060675620.022
cell activation involved in immune responseGO:00022631260.021
cellular response to external stimulusGO:0071496880.021
regulation of protein serine threonine kinase activityGO:00719001570.021
negative regulation of interleukin 6 productionGO:0032715170.021
neuron apoptotic processGO:00514021420.021
regulation of synaptic growth at neuromuscular junctionGO:000858240.021
endocrine system developmentGO:0035270980.021
cardioblast proliferationGO:000326380.021
cellular response to oxidative stressGO:0034599760.021
cellular response to acid chemicalGO:0071229680.021
b cell activation involved in immune responseGO:0002312500.021
carbohydrate metabolic processGO:00059752300.021
regulation of cell morphogenesis involved in differentiationGO:00107691510.020
t cell receptor signaling pathwayGO:0050852460.020
leukocyte mediated immunityGO:00024431740.020
nuclear divisionGO:00002801580.020
regulation of neuron apoptotic processGO:00435231220.020
establishment or maintenance of cell polarityGO:0007163860.020
interleukin 8 productionGO:003263740.020
positive regulation of cellular catabolic processGO:00313311480.020
glycoprotein metabolic processGO:00091001160.020
regulation of mapk cascadeGO:00434082480.020
cellular protein complex assemblyGO:00436231160.020
regulation of antibacterial peptide biosynthetic processGO:000280810.020
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.020
dendritic cell differentiationGO:0097028260.020
regulation of actin filament based processGO:0032970990.020
regulation of interleukin 12 productionGO:0032655300.020
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.020
development of primary sexual characteristicsGO:00451371430.020
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.019
t helper cell differentiationGO:0042093280.019
mechanoreceptor differentiationGO:0042490670.019
macromolecule deacylationGO:0098732370.019
aorta morphogenesisGO:0035909220.019
antibacterial peptide productionGO:000277820.019
regulation of cell activationGO:00508652890.019
regulation of feeding behaviorGO:006025930.019
protein autoprocessingGO:001654020.019
regulation of tumor necrosis factor mediated signaling pathwayGO:001080330.019
negative regulation of cell proliferationGO:00082852960.019
regulation of b cell proliferationGO:0030888390.019
regulation of protein catabolic processGO:00421761080.019
positive regulation of mapk cascadeGO:00434101700.019
defense response to other organismGO:00985421970.019
ion transmembrane transportGO:00342203610.019
divalent metal ion transportGO:00708381720.019
learning or memoryGO:00076111480.019
odontogenesis of dentin containing toothGO:0042475660.018
regulation of leukocyte differentiationGO:19021051590.018
immunoglobulin productionGO:0002377730.018
regulation of protein localization to nucleusGO:1900180600.018
Mouse
positive regulation of intracellular transportGO:0032388700.018
Mouse
lymphocyte homeostasisGO:0002260640.018
endomembrane system organizationGO:00102561470.018
organic hydroxy compound metabolic processGO:19016152030.018
germ cell developmentGO:00072811850.018
cell substrate adhesionGO:00315891300.018
ribonucleotide metabolic processGO:00092592910.018
salivary gland morphogenesisGO:0007435330.018
negative regulation of cell fate commitmentGO:001045480.018
positive regulation of t cell activationGO:00508701010.018
neuron fate specificationGO:0048665300.018
cellular chemical homeostasisGO:00550822150.018
female gamete generationGO:0007292740.018
regulation of defense response to bacteriumGO:190042430.018
response to organonitrogen compoundGO:00102432460.018
regulation of vesicle mediated transportGO:00606271390.018
kidney morphogenesisGO:0060993830.018
cellular calcium ion homeostasisGO:00068741190.018
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.017
muscle cell differentiationGO:00426922610.017
positive regulation of antibacterial peptide biosynthetic processGO:000696310.017
regulation of cell projection organizationGO:00313442060.017
cellular homeostasisGO:00197252400.017
regulation of protein secretionGO:0050708820.017
regulation of system processGO:00440572000.017
regulation of cytoskeleton organizationGO:00514931220.017
interferon beta biosynthetic processGO:004535040.017
neuromuscular processGO:0050905990.017
establishment of mitotic spindle localizationGO:0040001120.017
positive regulation of reactive oxygen species metabolic processGO:2000379110.017
multicellular organism growthGO:00352641610.017
positive regulation of bindingGO:0051099490.017
regulation of organ formationGO:0003156340.017
positive regulation of map kinase activityGO:0043406840.017
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.017
negative regulation of cell developmentGO:00107211690.017
nucleoside phosphate metabolic processGO:00067533380.017
cell fate commitment involved in formation of primary germ layerGO:0060795260.017
regulation of peptidase activityGO:0052547960.017
positive regulation of inflammatory responseGO:0050729470.017
regulation of protein maturationGO:1903317960.017
regulation of protein bindingGO:0043393600.017
tissue remodelingGO:00487711020.017
regulation of embryonic developmentGO:0045995710.017
sequestering of calcium ionGO:0051208180.016
mesodermal cell differentiationGO:0048333220.016
epithelial cell developmentGO:00020641590.016
organic cyclic compound catabolic processGO:19013612950.016
lipopolysaccharide mediated signaling pathwayGO:0031663250.016
water homeostasisGO:0030104270.016
purine nucleotide catabolic processGO:00061952110.016
morphogenesis of embryonic epitheliumGO:00163311590.016
negative regulation of cell activationGO:00508661110.016
response to reactive oxygen speciesGO:0000302560.016
regulation of cellular catabolic processGO:00313292420.016
humoral immune responseGO:0006959570.016
establishment of spindle localizationGO:0051293190.016
glandular epithelial cell differentiationGO:0002067380.016
pallium developmentGO:00215431200.016
muscle system processGO:00030121410.016
carbohydrate transportGO:0008643620.016
negative regulation of chemokine productionGO:003268240.016

Sharpin disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.031
central nervous system diseaseDOID:33100.031
disease of anatomical entityDOID:700.031
disease of metabolismDOID:001466700.024