Mus musculus

94 known processes

Aplf

aprataxin and PNKP like factor

(Aliases: 2010301N04Rik,AI452191)

Aplf biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.112
cellular amine metabolic processGO:0044106440.071
cellular ketone metabolic processGO:0042180840.066
regulation of cellular amino acid metabolic processGO:000652150.063
regulation of cellular ketone metabolic processGO:0010565660.056
cellular amino acid metabolic processGO:00065201030.053
positive regulation of cellular amino acid metabolic processGO:004576430.043
microtubule based processGO:00070172360.040
cellular response to dna damage stimulusGO:00069742070.040
regulation of organelle organizationGO:00330432890.039
amine metabolic processGO:0009308450.039
regulation of cellular amine metabolic processGO:0033238200.038
male gamete generationGO:00482322850.037
gland developmentGO:00487323300.036
regulation of cell activationGO:00508652890.036
transmembrane transportGO:00550854120.034
microtubule cytoskeleton organizationGO:00002261570.033
cation transportGO:00068123990.033
purine containing compound metabolic processGO:00725213110.032
dna recombinationGO:0006310920.032
nucleotide metabolic processGO:00091173320.032
muscle tissue developmentGO:00605373080.031
mitotic cell cycleGO:00002781950.031
ribose phosphate metabolic processGO:00196932910.031
striated muscle tissue developmentGO:00147062930.030
positive regulation of cellular amine metabolic processGO:003324050.029
nuclear divisionGO:00002801580.028
apoptotic signaling pathwayGO:00971903060.028
cellular nitrogen compound catabolic processGO:00442702800.028
nucleoside metabolic processGO:00091162460.028
peptidyl amino acid modificationGO:00181933360.027
chromatin modificationGO:00165681870.027
nucleobase containing small molecule metabolic processGO:00550863520.027
ribonucleotide metabolic processGO:00092592910.027
heterocycle catabolic processGO:00467002800.026
cell type specific apoptotic processGO:00972852680.026
leukocyte differentiationGO:00025213420.026
regulation of cell cycleGO:00517262810.026
t cell activationGO:00421102890.026
regulation of hydrolase activityGO:00513362460.026
purine nucleotide metabolic processGO:00061633020.026
glycosyl compound catabolic processGO:19016582060.025
regulation of lymphocyte activationGO:00512492400.024
nucleoside triphosphate catabolic processGO:00091432050.024
aromatic compound catabolic processGO:00194392860.024
purine ribonucleoside metabolic processGO:00461282410.024
glycosyl compound metabolic processGO:19016572460.023
spermatogenesisGO:00072832840.023
negative regulation of immune system processGO:00026832090.023
organonitrogen compound catabolic processGO:19015652640.022
respiratory system developmentGO:00605411900.022
homeostasis of number of cellsGO:00488722100.022
carbohydrate derivative catabolic processGO:19011362310.022
ribonucleoside metabolic processGO:00091192450.022
germ cell developmentGO:00072811850.022
ribonucleoside catabolic processGO:00424542060.022
regulation of t cell activationGO:00508631700.022
compound eye developmentGO:004874910.022
cell adhesionGO:00071553290.022
sequestering of metal ionGO:0051238190.022
cytoplasmic transportGO:00164822340.021
organophosphate catabolic processGO:00464342320.021
nucleoside phosphate catabolic processGO:19012922220.021
nucleoside phosphate metabolic processGO:00067533380.021
regionalizationGO:00030023370.021
purine ribonucleotide catabolic processGO:00091542080.021
positive regulation of protein modification processGO:00314012990.021
organic cyclic compound catabolic processGO:19013612950.021
organelle fissionGO:00482851700.021
maintenance of locationGO:0051235890.021
negative regulation of cellular component organizationGO:00511291940.020
purine nucleoside metabolic processGO:00422782410.020
inorganic cation transmembrane transportGO:00986622070.020
cytokine productionGO:00018163190.020
inorganic ion transmembrane transportGO:00986602340.020
cellular homeostasisGO:00197252400.020
camera type eye developmentGO:00430102660.020
myeloid cell differentiationGO:00300992330.020
nucleoside triphosphate metabolic processGO:00091412300.020
cation transmembrane transportGO:00986552660.020
cell divisionGO:00513011200.020
lymphocyte mediated immunityGO:00024491390.019
posttranscriptional regulation of gene expressionGO:00106081550.019
regulation of cell cycle processGO:00105641600.019
regulation of secretion by cellGO:19035302490.019
histone modificationGO:00165701590.019
chemotaxisGO:00069352470.019
purine ribonucleoside triphosphate metabolic processGO:00092052200.019
divalent inorganic cation transportGO:00725111780.019
purine ribonucleoside catabolic processGO:00461302050.019
covalent chromatin modificationGO:00165691630.018
ribonucleoside triphosphate metabolic processGO:00091992200.018
purine nucleoside catabolic processGO:00061522050.018
divalent metal ion transportGO:00708381720.018
skeletal muscle organ developmentGO:00605381630.018
ion transmembrane transportGO:00342203610.018
purine ribonucleotide metabolic processGO:00091502900.018
chromatin organizationGO:00063252060.018
nucleoside catabolic processGO:00091642060.018
regulation of homeostatic processGO:00328441820.018
cell activation involved in immune responseGO:00022631260.018
immune effector processGO:00022523210.018
organelle localizationGO:00516401790.018
purine nucleotide catabolic processGO:00061952110.017
sequestering of calcium ionGO:0051208180.017
regulation of cellular component biogenesisGO:00440871810.017
wnt signaling pathwayGO:00160551880.017
embryonic organ morphogenesisGO:00485622760.017
regulation of chromosome organizationGO:0033044830.017
positive regulation of protein phosphorylationGO:00019342420.017
meiotic nuclear divisionGO:00071261150.017
regulation of synaptic growth at neuromuscular junctionGO:000858240.017
lymphocyte differentiationGO:00300982420.017
adaptive immune responseGO:00022501550.017
positive regulation of programmed cell deathGO:00430682180.017
purine nucleoside triphosphate catabolic processGO:00091462030.017
small gtpase mediated signal transductionGO:0007264970.017
sensory perceptionGO:00076002450.017
leukocyte activation involved in immune responseGO:00023661260.017
macromolecule catabolic processGO:00090572810.017
skeletal system developmentGO:00015013560.017
negative regulation of protein metabolic processGO:00512482820.017
epithelial cell proliferationGO:00506731740.017
regulation of system processGO:00440572000.017
protein modification by small protein conjugation or removalGO:00706472070.016
regulation of membrane potentialGO:00423911920.016
positive regulation of nervous system developmentGO:00519622210.016
cellular macromolecule catabolic processGO:00442652060.016
regulation of muscle tissue developmentGO:1901861970.016
meiosis iGO:0007127600.016
positive regulation of cell developmentGO:00107202370.016
anatomical structure homeostasisGO:00602491450.016
regulation of protein kinase activityGO:00458592320.016
axonogenesisGO:00074092740.016
nitrogen compound transportGO:00717052710.016
sensory organ morphogenesisGO:00905962420.016
purine nucleoside triphosphate metabolic processGO:00091442260.016
regulation of neuron differentiationGO:00456642810.016
muscle cell differentiationGO:00426922610.016
intrinsic apoptotic signaling pathwayGO:00971931320.016
organonitrogen compound biosynthetic processGO:19015661920.016
alpha beta t cell activationGO:0046631910.016
regulation of establishment of protein localizationGO:00702011810.016
epithelial tube morphogenesisGO:00605623030.016
regulation of mitotic cell cycleGO:00073461260.016
negative regulation of cellular protein metabolic processGO:00322692470.016
nucleotide catabolic processGO:00091662170.015
negative regulation of intracellular signal transductionGO:19025321670.015
dna repairGO:00062811070.015
kidney developmentGO:00018222130.015
regulation of ion transportGO:00432692150.015
regulation of mapk cascadeGO:00434082480.015
cellular response to cytokine stimulusGO:00713451890.015
protein ubiquitinationGO:00165671710.015
branching morphogenesis of an epithelial tubeGO:00487541590.015
developmental maturationGO:00217001930.015
rna processingGO:00063961050.015
b cell activationGO:00421131610.015
cell maturationGO:00484691270.015
fat cell differentiationGO:00454441600.015
regulation of cell morphogenesis involved in differentiationGO:00107691510.015
positive regulation of organelle organizationGO:00106381280.015
placenta developmentGO:00018901400.015
ribonucleoside triphosphate catabolic processGO:00092031990.015
negative regulation of cellular amino acid metabolic processGO:004576300.015
regulation of protein localizationGO:00328802310.015
regulation of cell cycle phase transitionGO:1901987770.014
ribonucleotide catabolic processGO:00092612080.014
nuclear transportGO:00511691390.014
digestive tract developmentGO:00485651900.014
rho protein signal transductionGO:0007266320.014
organic hydroxy compound metabolic processGO:19016152030.014
forebrain developmentGO:00309003020.014
regulation of cell projection organizationGO:00313442060.014
mapk cascadeGO:00001652810.014
morphogenesis of a branching epitheliumGO:00611381930.014
positive regulation of cell deathGO:00109422240.014
mitotic cell cycle processGO:19030471590.014
limb morphogenesisGO:00351081490.014
negative regulation of cellular amine metabolic processGO:003323910.014
purine containing compound catabolic processGO:00725232130.014
cellular lipid metabolic processGO:00442553230.014
morphogenesis of a branching structureGO:00017632030.014
protein modification by small protein conjugationGO:00324461870.014
carbohydrate derivative biosynthetic processGO:19011371830.014
negative regulation of nervous system developmentGO:00519611560.014
limb developmentGO:00601731660.014
regulation of anatomical structure sizeGO:00900661780.014
regulation of purine nucleotide metabolic processGO:19005421690.014
skin developmentGO:00435882200.014
epithelial cell developmentGO:00020641590.014
cellular chemical homeostasisGO:00550822150.014
calcium ion transportGO:00068161590.014
lung developmentGO:00303241640.014
cellular component assembly involved in morphogenesisGO:00109271390.014
t cell differentiationGO:00302171740.014
regulation of hormone levelsGO:00108172110.014
lipid biosynthetic processGO:00086101790.014
endomembrane system organizationGO:00102561470.014
cellular response to lipidGO:00713961450.013
spermatid developmentGO:00072861080.013
spermatid differentiationGO:00485151150.013
regulation of apoptotic signaling pathwayGO:20012331970.013
organelle assemblyGO:00709251770.013
asymmetric stem cell divisionGO:009872230.013
sensory perception of soundGO:0007605970.013
oxidation reduction processGO:00551143420.013
negative regulation of cell cycleGO:00457861230.013
regulation of cellular catabolic processGO:00313292420.013
respiratory tube developmentGO:00303231670.013
peptidyl lysine modificationGO:0018205770.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.013
ras protein signal transductionGO:0007265770.013
negative regulation of molecular functionGO:00440922580.013
reactive oxygen species metabolic processGO:0072593840.013
myeloid leukocyte differentiationGO:00025731190.013
oocyte axis specificationGO:000730920.013
guanosine containing compound catabolic processGO:19010691440.013
actin cytoskeleton organizationGO:00300362200.013
positive regulation of cell activationGO:00508671580.013
regulation of cytokine productionGO:00018172660.013
developmental growth involved in morphogenesisGO:00605601380.013
purine ribonucleoside triphosphate catabolic processGO:00092071990.013
positive regulation of cytokine productionGO:00018191740.013
response to organonitrogen compoundGO:00102432460.013
lymphocyte activation involved in immune responseGO:0002285930.013
negative regulation of phosphate metabolic processGO:00459361840.013
negative regulation of synapse assemblyGO:005196430.013
regulation of secretionGO:00510462740.013
response to organic cyclic compoundGO:00140701980.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.012
negative regulation of apoptotic signaling pathwayGO:20012341040.012
epidermis developmentGO:00085441870.012
establishment of organelle localizationGO:00516561220.012
male genitalia morphogenesisGO:004880840.012
stem cell proliferationGO:00720891170.012
regulation of defense responseGO:00313472330.012
lateral inhibitionGO:004633110.012
blood circulationGO:00080151950.012
ear developmentGO:00435832000.012
synaptic transmissionGO:00072683290.012
protein localization to organelleGO:00333651850.012
negative regulation of organelle organizationGO:0010639900.012
intracellular protein transportGO:00068862040.012
regulation of lymphocyte proliferationGO:00506701170.012
response to radiationGO:00093141650.012
hematopoietic progenitor cell differentiationGO:00022441430.012
nucleocytoplasmic transportGO:00069131390.012
male sex differentiationGO:00466611090.012
regulation of epithelial cell proliferationGO:00506781410.012
positive regulation of apoptotic processGO:00430652170.012
negative regulation of cell cycle processGO:0010948690.012
regulation of ion transmembrane transportGO:00347651190.012
regulation of mitotic cell cycle phase transitionGO:1901990730.012
mitotic cytokinesisGO:000028140.012
asymmetric neuroblast divisionGO:005505910.012
urogenital system developmentGO:00016552610.012
meiotic cell cycleGO:00513211220.012
neural precursor cell proliferationGO:00613511210.012
regulation of intracellular transportGO:00323861590.012
transmission of nerve impulseGO:0019226760.012
response to lipopolysaccharideGO:00324961280.012
anion transportGO:00068201770.012
protein maturationGO:00516041760.012
gtp metabolic processGO:00460391440.012
oocyte constructionGO:000730820.012
regulation of nucleotide metabolic processGO:00061401690.012
negative regulation of cell proliferationGO:00082852960.012
digestive tract morphogenesisGO:00485461470.012
nucleic acid phosphodiester bond hydrolysisGO:0090305490.012
blood vessel morphogenesisGO:00485142850.012
ossificationGO:00015032160.012
leukocyte mediated immunityGO:00024431740.011
regulation of body fluid levelsGO:00508781620.011
connective tissue developmentGO:00614481790.011
protein polymerizationGO:0051258570.011
positive regulation of cellular component biogenesisGO:0044089940.011
multicellular organism growthGO:00352641610.011
chromosome segregationGO:0007059480.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
leukocyte proliferationGO:00706611720.011
embryonic limb morphogenesisGO:00303261260.011
membrane organizationGO:00610242450.011
somatic diversification of immune receptorsGO:0002200530.011
synapse organizationGO:00508081250.011
locomotory behaviorGO:00076261950.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
appendage morphogenesisGO:00351071490.011
stem cell maintenanceGO:00198271300.011
positive regulation of hydrolase activityGO:00513451480.011
cellular response to organonitrogen compoundGO:00714171450.011
carbohydrate homeostasisGO:00335001280.011
pharynx developmentGO:006046510.011
protein autophosphorylationGO:0046777610.011
protein localization to nucleusGO:00345041210.011
negative regulation of protein modification processGO:00314001630.011
adult behaviorGO:00305341350.011
guanosine containing compound metabolic processGO:19010681440.011
response to growth factorGO:00708481980.011
blastocyst developmentGO:0001824800.011
regulation of lymphocyte differentiationGO:00456191070.011
extracellular matrix organizationGO:00301981470.011
multicellular organismal homeostasisGO:00488711640.011
neural tube developmentGO:00219151600.011
lymphocyte proliferationGO:00466511640.011
cellular response to acid chemicalGO:0071229680.011
positive regulation of cell cycleGO:0045787920.011
regulation of chromatin organizationGO:1902275570.011
gtp catabolic processGO:00061841430.011
skeletal system morphogenesisGO:00487052030.011
digestive system developmentGO:00551232000.011
tube formationGO:00351481400.011
epithelial tube formationGO:00721751300.011
embryonic placenta developmentGO:0001892980.011
positive regulation of secretionGO:00510471300.011
intracellular mrna localizationGO:000829840.010
stem cell developmentGO:00488642190.010
cellular protein catabolic processGO:00442571550.010
metal ion homeostasisGO:00550651890.010
response to acid chemicalGO:00011011110.010
regulation of cellular component sizeGO:00325351210.010
regulation of protein transportGO:00512231630.010
male anatomical structure morphogenesisGO:009059840.010
endocytosisGO:00068971680.010
fertilizationGO:00095661270.010
cellular response to growth factor stimulusGO:00713631970.010
methylationGO:00322591340.010
glycerolipid metabolic processGO:00464861220.010
multicellular organismal signalingGO:0035637910.010
negative regulation of phosphorus metabolic processGO:00105631840.010
regulation of leukocyte differentiationGO:19021051590.010
muscle cell developmentGO:00550011330.010
innate immune responseGO:00450871570.010
mitotic nuclear divisionGO:0007067480.010
negative regulation of cell developmentGO:00107211690.010
regulation of leukocyte proliferationGO:00706631210.010
negative regulation of phosphorylationGO:00423261660.010
response to inorganic substanceGO:0010035960.010
heart morphogenesisGO:00030071780.010
myeloid cell homeostasisGO:00022621140.010
positive regulation of neuron differentiationGO:00456661410.010
regulation of alpha beta t cell activationGO:0046634530.010

Aplf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.032
immune system diseaseDOID:291400.032
nervous system diseaseDOID:86300.023
musculoskeletal system diseaseDOID:1700.019
cancerDOID:16200.015
organ system cancerDOID:005068600.015
disease of cellular proliferationDOID:1456600.015
muscular diseaseDOID:008000000.015
hematopoietic system diseaseDOID:7400.014
disease of metabolismDOID:001466700.014
central nervous system diseaseDOID:33100.013
connective tissue diseaseDOID:6500.010