Mus musculus

101 known processes

E2f1

E2F transcription factor 1

(Aliases: mKIAA4009,E2F-1,KIAA4009)

E2f1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069742070.997
Human
dna metabolic processGO:00062593030.995
Fly
g1 s transition of mitotic cell cycleGO:0000082570.992
Human Mouse
regulation of cell cycleGO:00517262810.992
regulation of cell cycle phase transitionGO:1901987770.978
Human
regulation of mitotic cell cycle phase transitionGO:1901990730.969
Human
negative regulation of cell cycleGO:00457861230.941
negative regulation of cell cycle phase transitionGO:1901988480.934
regulation of mitotic cell cycleGO:00073461260.932
Human
dna repairGO:00062811070.925
dna endoreduplicationGO:004202340.922
Fly
cell cycle g1 s phase transitionGO:0044843570.918
Human Mouse
negative regulation of mitotic cell cycleGO:0045930580.901
mitotic cell cycleGO:00002781950.885
Human Mouse
dna damage checkpointGO:0000077260.863
Human
negative regulation of mitotic cell cycle phase transitionGO:1901991450.850
positive regulation of programmed cell deathGO:00430682180.833
Fly
dna integrity checkpointGO:0031570280.808
Human
apoptotic signaling pathwayGO:00971903060.788
cell cycle checkpointGO:0000075470.784
Human
positive regulation of apoptotic processGO:00430652170.761
Fly
gland developmentGO:00487323300.760
intrinsic apoptotic signaling pathwayGO:00971931320.756
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.737
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.732
regulation of cell cycle processGO:00105641600.710
Human
double strand break repairGO:0006302480.701
signal transduction by p53 class mediatorGO:0072331510.691
response to ionizing radiationGO:0010212420.637
chromatin organizationGO:00063252060.634
mitotic cell cycle checkpointGO:0007093310.634
cell type specific apoptotic processGO:00972852680.628
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.591
carbohydrate metabolic processGO:00059752300.590
response to radiationGO:00093141650.582
negative regulation of cell proliferationGO:00082852960.560
response to light stimulusGO:00094161350.546
dna biosynthetic processGO:0071897220.546
mitotic cell cycle processGO:19030471590.530
Human Mouse
dna recombinationGO:0006310920.525
anoikisGO:004327660.517
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.506
Human
gene silencingGO:0016458380.476
cajal body organizationGO:003057610.476
regulation of transcription involved in g1 s transition of mitotic cell cycleGO:000008330.474
Human Mouse
protein modification by small protein conjugation or removalGO:00706472070.470
regulation of cellular amine metabolic processGO:0033238200.463
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.451
Human
regulation of anatomical structure sizeGO:00900661780.447
Mouse
meiotic cell cycle processGO:1903046770.407
protein ubiquitinationGO:00165671710.406
oogenesisGO:0048477560.403
Fly
response to oxidative stressGO:00069791230.398
dna replicationGO:0006260520.386
Fly
cellular amine metabolic processGO:0044106440.381
chromosome segregationGO:0007059480.380
cellular amino acid metabolic processGO:00065201030.376
negative regulation of phosphorylationGO:00423261660.370
humoral immune responseGO:0006959570.368
Fly
regulation of cellular component sizeGO:00325351210.364
Mouse
regulation of cell sizeGO:0008361720.360
Mouse
negative regulation of dna replicationGO:000815640.356
ubiquitin dependent protein catabolic processGO:00065111290.356
protein maturationGO:00516041760.354
neural precursor cell proliferationGO:00613511210.335
response to organonitrogen compoundGO:00102432460.335
negative regulation of phosphorus metabolic processGO:00105631840.335
negative regulation of molecular functionGO:00440922580.331
mitotic sister chromatid cohesionGO:000706410.325
cellular response to growth factor stimulusGO:00713631970.319
regulation of cell cycle g2 m phase transitionGO:1902749100.315
cell cycle arrestGO:0007050370.314
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.311
positive regulation of defense response to bacteriumGO:190042610.309
negative regulation of cell cycle processGO:0010948690.308
positive regulation of cell deathGO:00109422240.305
Fly
germ cell developmentGO:00072811850.303
Fly
regulation of cell cycle g1 s phase transitionGO:1902806350.295
Human
positive regulation of cysteine type endopeptidase activityGO:2001056390.289
cellular response to oxidative stressGO:0034599760.287
regulation of cellular catabolic processGO:00313292420.285
positive regulation of cell developmentGO:00107202370.279
Fly
response to growth factorGO:00708481980.279
regulation of dna replicationGO:0006275170.278
spermatogenesisGO:00072832840.277
mitotic g2 dna damage checkpointGO:000709580.276
intra s dna damage checkpointGO:003157340.272
regulation of g1 s transition of mitotic cell cycleGO:2000045350.253
Human
male gamete generationGO:00482322850.251
response to transforming growth factor betaGO:0071559880.249
regulation of cohesin localization to chromatinGO:007192210.249
protein processingGO:00164851630.248
muscle cell differentiationGO:00426922610.245
regulation of protein kinase activityGO:00458592320.241
organonitrogen compound biosynthetic processGO:19015661920.239
regulation of cysteine type endopeptidase activityGO:2000116650.234
regulation of neural precursor cell proliferationGO:2000177700.229
modification dependent protein catabolic processGO:00199411330.228
regulation of intracellular transportGO:00323861590.226
cell cycle g2 m phase transitionGO:0044839200.225
cellular homeostasisGO:00197252400.222
Mouse
negative regulation of kinase activityGO:0033673810.221
regulation of cytoplasmic transportGO:19036491120.220
negative regulation of phosphate metabolic processGO:00459361840.219
cellular protein catabolic processGO:00442571550.218
myeloid cell differentiationGO:00300992330.209
response to heatGO:0009408270.206
cellular ketone metabolic processGO:0042180840.204
regulation of protein localizationGO:00328802310.204
meiosis iGO:0007127600.203
nuclear divisionGO:00002801580.202
stem cell proliferationGO:00720891170.201
negative regulation of protein serine threonine kinase activityGO:0071901490.198
chromatin silencingGO:0006342150.198
regulation of neuron apoptotic processGO:00435231220.196
cellular response to external stimulusGO:0071496880.195
nucleosome disassemblyGO:000633710.194
meiotic cell cycleGO:00513211220.194
protein catabolic processGO:00301632210.193
negative regulation of cellular amino acid metabolic processGO:004576300.192
cell fate commitmentGO:00451652100.190
regulation of endopeptidase activityGO:0052548890.190
cohesin localization to chromatinGO:007192110.186
regulation of bindingGO:00510981110.186
regionalizationGO:00030023370.186
cellular response to organonitrogen compoundGO:00714171450.186
response to oxygen levelsGO:0070482620.185
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.185
macromolecule catabolic processGO:00090572810.183
negative regulation of protein phosphorylationGO:00019331260.180
rhythmic processGO:00485111740.179
negative regulation of cell cycle g1 s phase transitionGO:1902807180.176
forebrain developmentGO:00309003020.174
regulation of chromosome organizationGO:0033044830.174
covalent chromatin modificationGO:00165691630.173
erythrocyte differentiationGO:0030218880.172
regulation of neuroblast proliferationGO:1902692270.170
neural tube formationGO:00018411080.167
cell divisionGO:00513011200.166
proteolysis involved in cellular protein catabolic processGO:00516031470.166
positive regulation of organelle organizationGO:00106381280.165
chromatin modificationGO:00165681870.165
regulation of apoptotic signaling pathwayGO:20012331970.163
cellular response to transforming growth factor beta stimulusGO:0071560880.160
negative regulation of g1 s transition of mitotic cell cycleGO:2000134180.159
negative regulation of transferase activityGO:0051348850.159
regulation of intracellular protein transportGO:0033157820.159
regulation of hydrolase activityGO:00513362460.157
cilium morphogenesisGO:00602711020.156
Mouse
cellular response to nutrient levelsGO:0031669640.156
ossificationGO:00015032160.156
carbohydrate derivative biosynthetic processGO:19011371830.153
negative regulation of immune system processGO:00026832090.153
neuron apoptotic processGO:00514021420.152
neural tube developmentGO:00219151600.152
negative regulation of neural precursor cell proliferationGO:2000178180.151
embryonic epithelial tube formationGO:00018381300.150
positive regulation of histone methylationGO:0031062160.148
homeostasis of number of cellsGO:00488722100.148
regulation of cell divisionGO:0051302760.144
dna dependent dna replicationGO:0006261240.140
g2 m transition of mitotic cell cycleGO:0000086200.138
mitotic g1 dna damage checkpointGO:003157140.137
regulation of cellular amino acid metabolic processGO:000652150.137
regulation of peptidase activityGO:0052547960.136
meiotic nuclear divisionGO:00071261150.135
negative regulation of protein metabolic processGO:00512482820.134
neuron deathGO:00709971540.134
regulation of stem cell proliferationGO:0072091780.133
negative regulation of neuron deathGO:1901215980.132
signal transduction involved in dna damage checkpointGO:007242230.131
base excision repairGO:000628490.131
primary neural tube formationGO:0014020950.130
positive regulation of apoptotic signaling pathwayGO:2001235950.130
organelle fissionGO:00482851700.130
regulation of organelle organizationGO:00330432890.130
signal transduction involved in dna integrity checkpointGO:007240130.128
chromatin disassemblyGO:003149810.128
axonogenesisGO:00074092740.127
cellular response to peptide hormone stimulusGO:0071375920.127
regulation of protein targetingGO:1903533610.126
positive regulation of cell cycleGO:0045787920.123
apoptotic process involved in developmentGO:1902742280.122
Fly
carbohydrate homeostasisGO:00335001280.122
response to peptide hormoneGO:00434341270.122
peptidyl amino acid modificationGO:00181933360.122
response to peptideGO:19016521360.121
cytoplasmic transportGO:00164822340.121
organic cyclic compound catabolic processGO:19013612950.120
regulation of transcription regulatory region dna bindingGO:200067790.120
positive regulation of endopeptidase activityGO:0010950430.117
positive regulation of multi organism processGO:0043902260.117
Fly
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.113
mitotic nuclear divisionGO:0007067480.112
positive regulation of proteolysisGO:0045862850.111
response to reactive oxygen speciesGO:0000302560.110
antibacterial peptide biosynthetic processGO:000278020.110
mitotic chromosome condensationGO:000707610.109
regulation of secretionGO:00510462740.109
negative regulation of protein modification processGO:00314001630.107
oocyte differentiationGO:0009994350.107
pallium developmentGO:00215431200.106
b cell activationGO:00421131610.106
recombinational repairGO:0000725210.106
maintenance of locationGO:0051235890.106
cellular response to insulin stimulusGO:0032869780.106
positive regulation of mitotic sister chromatid separationGO:190197020.105
regulation of actin cytoskeleton organizationGO:0032956840.105
regulation of leukocyte apoptotic processGO:2000106560.105
positive regulation of keratinocyte proliferationGO:001083840.105
nuclear transportGO:00511691390.105
dna dependent dna replication maintenance of fidelityGO:004500530.104
intracellular protein transportGO:00068862040.104
negative regulation of growthGO:0045926990.103
cellular macromolecule catabolic processGO:00442652060.103
telencephalon developmentGO:00215371860.103
regulation of cytokine productionGO:00018172660.103
modification dependent macromolecule catabolic processGO:00436321330.102
regulation of defense response to bacteriumGO:190042430.102
regulation of transferase activityGO:00513382630.102
negative regulation of intracellular signal transductionGO:19025321670.101
anatomical structure homeostasisGO:00602491450.101
negative regulation of gene expression epigeneticGO:0045814150.101
response to oxygen radicalGO:0000305160.101
regulation of multi organism processGO:00439001110.100
Fly
striated muscle tissue developmentGO:00147062930.100
single organism nuclear importGO:1902593950.100
cellular protein complex assemblyGO:00436231160.099
antimicrobial peptide productionGO:000277520.099
regulation of protein catabolic processGO:00421761080.099
protein modification by small protein conjugationGO:00324461870.099
glucose homeostasisGO:00425931280.098
negative regulation of cellular amine metabolic processGO:003323910.098
heterocycle catabolic processGO:00467002800.098
response to hypoxiaGO:0001666580.097
regulation of cell motilityGO:20001452360.097
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.096
methylationGO:00322591340.096
purine ribonucleotide metabolic processGO:00091502900.095
positive regulation of chromosome segregationGO:005198440.095
mitochondrion organizationGO:00070051340.095
blood vessel morphogenesisGO:00485142850.095
cell adhesionGO:00071553290.095
embryonic organ morphogenesisGO:00485622760.095
angiogenesisGO:00015252010.095
regulation of exit from mitosisGO:000709610.094
regulation of protein modification by small protein conjugation or removalGO:1903320570.094
positive regulation of chromosome organizationGO:2001252330.094
production of molecular mediator of immune responseGO:00024401030.094
skeletal system developmentGO:00015013560.092
purine containing compound metabolic processGO:00725213110.092
gliogenesisGO:00420631410.092
positive regulation of cellular catabolic processGO:00313311480.092
antimicrobial peptide biosynthetic processGO:000277720.089
positive regulation of peptidase activityGO:0010952490.089
negative regulation of hydrolase activityGO:0051346710.088
dendrite developmentGO:00163581150.088
Fly
organelle assemblyGO:00709251770.087
Mouse
tube formationGO:00351481400.086
response to superoxideGO:0000303160.086
female gamete generationGO:0007292740.086
Fly
myeloid cell homeostasisGO:00022621140.085
macromolecule methylationGO:00434141200.085
oxidation reduction processGO:00551143420.084
transforming growth factor beta receptor signaling pathwayGO:0007179710.084
regulation of mast cell differentiationGO:006037530.083
regulation of kinase activityGO:00435492490.083
glial cell apoptotic processGO:003434930.083
cellular response to extracellular stimulusGO:0031668810.083
regulation of sequence specific dna binding transcription factor activityGO:00510901060.082
double strand break repair via homologous recombinationGO:0000724210.081
cellular response to peptideGO:1901653920.081
apoptotic mitochondrial changesGO:0008637480.080
regulation of synaptic plasticityGO:0048167870.079
multicellular organism growthGO:00352641610.079
regulation of neuron deathGO:19012141340.079
cellular carbohydrate metabolic processGO:00442621190.079
regulation of protein import into nucleusGO:0042306520.078
purine ribonucleoside metabolic processGO:00461282410.078
negative regulation of cellular protein metabolic processGO:00322692470.078
t cell activationGO:00421102890.078
response to inorganic substanceGO:0010035960.078
regulation of protein serine threonine kinase activityGO:00719001570.077
positive regulation of reproductive processGO:2000243190.077
Fly
lymphocyte differentiationGO:00300982420.077
protein localization to organelleGO:00333651850.076
regulation of histone modificationGO:0031056560.076
positive regulation of mitotic cell cycleGO:0045931410.076
protein polyubiquitinationGO:0000209330.076
negative regulation of stem cell proliferationGO:2000647120.076
positive regulation of protein modification processGO:00314012990.076
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.076
regulation of proteolysisGO:00301621640.075
locomotory behaviorGO:00076261950.075
regulation of transcription by chromatin organizationGO:003440100.075
cilium assemblyGO:0042384810.075
Mouse
regulation of reactive oxygen species metabolic processGO:2000377400.075
positive regulation of hydrolase activityGO:00513451480.074
negative regulation of neuroblast proliferationGO:000740670.074
nucleoside phosphate catabolic processGO:19012922220.074
g2 dna damage checkpointGO:003157280.073
regulation of protein transportGO:00512231630.073
response to organic cyclic compoundGO:00140701980.073
negative regulation of nervous system developmentGO:00519611560.072
regulation of cellular component biogenesisGO:00440871810.072
dna damage response signal transduction by p53 class mediatorGO:0030330190.071
mitotic cell cycle arrestGO:007185040.071
ribonucleoside metabolic processGO:00091192450.071
liver developmentGO:0001889660.071
cellular response to oxygen radicalGO:0071450140.070
multicellular organismal homeostasisGO:00488711640.069
response to decreased oxygen levelsGO:0036293590.069
leukocyte differentiationGO:00025213420.069
release of cytochrome c from mitochondriaGO:0001836230.069
activation of cysteine type endopeptidase activityGO:0097202270.069
organophosphate biosynthetic processGO:00904071220.069
regulation of autophagyGO:0010506300.068
histone lysine methylationGO:0034968500.068
cellular component assembly involved in morphogenesisGO:00109271390.068
Mouse
dna conformation changeGO:0071103370.067
cell agingGO:0007569350.067
small gtpase mediated signal transductionGO:0007264970.067
macromolecule glycosylationGO:0043413550.066
regulation of nucleocytoplasmic transportGO:0046822730.066
regulation of protein localization to nucleusGO:1900180600.065
purine ribonucleoside catabolic processGO:00461302050.065
gonad developmentGO:00084061410.065
actin cytoskeleton organizationGO:00300362200.065
positive regulation of antimicrobial peptide productionGO:000222510.065
organonitrogen compound catabolic processGO:19015652640.065
glycosylationGO:0070085620.065
microtubule cytoskeleton organization involved in mitosisGO:190285040.064
regulation of proteasomal protein catabolic processGO:0061136460.064
positive regulation of transcription regulatory region dna bindingGO:200067910.064
nucleocytoplasmic transportGO:00069131390.064
response to temperature stimulusGO:0009266550.063
hepaticobiliary system developmentGO:0061008670.063
regulation of nuclear cell cycle dna replicationGO:003326220.063
carbohydrate derivative catabolic processGO:19011362310.063
developmental cell growthGO:0048588840.062
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.062
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.062
cell maturationGO:00484691270.062
lymphocyte apoptotic processGO:0070227540.062
cardiocyte differentiationGO:0035051870.062
rho protein signal transductionGO:0007266320.061
response to purine containing compoundGO:0014074280.061
actin filament organizationGO:00070151130.060
negative regulation of cell developmentGO:00107211690.059
positive regulation of cellular amine metabolic processGO:003324050.059
nucleotide excision repairGO:0006289130.059
protein import into nucleusGO:0006606950.059
neural tube closureGO:0001843900.058
regulation of chromatin modificationGO:1903308570.058
muscle tissue developmentGO:00605373080.058
Fly
defense response to other organismGO:00985421970.058
monosaccharide metabolic processGO:00059961060.058
organic hydroxy compound metabolic processGO:19016152030.057
male meiosisGO:0007140370.057
signal transduction involved in cell cycle checkpointGO:007239530.057
regulation of establishment of protein localizationGO:00702011810.057
glycosyl compound metabolic processGO:19016572460.057
ribonucleotide catabolic processGO:00092612080.057
protein glycosylationGO:0006486550.057
protein targetingGO:00066051430.057
extrinsic apoptotic signaling pathwayGO:00971911260.056
glucose metabolic processGO:0006006920.056
ribonucleoside catabolic processGO:00424542060.056
response to uvGO:0009411440.056
myeloid leukocyte differentiationGO:00025731190.056
positive regulation of mitotic metaphase anaphase transitionGO:004584220.055
peptidyl tyrosine modificationGO:00182121450.055
developmental growth involved in morphogenesisGO:00605601380.055
purine containing compound catabolic processGO:00725232130.055
negative regulation of cell sizeGO:004579230.055
regulation of dna bindingGO:0051101390.054
positive regulation of exit from mitosisGO:003153610.054
epithelial tube formationGO:00721751300.054
innate immune responseGO:00450871570.054
genetic imprintingGO:0071514270.054
reciprocal dna recombinationGO:0035825160.054
regulation of cellular protein catabolic processGO:1903362610.054
regulation of smad protein import into nucleusGO:006039030.054
hexose metabolic processGO:0019318980.054
purine nucleoside metabolic processGO:00422782410.053
intestinal epithelial structure maintenanceGO:006072940.053
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrestGO:000697730.053
positive regulation of histone modificationGO:0031058280.052
nucleoside catabolic processGO:00091642060.052
nucleoside triphosphate metabolic processGO:00091412300.052
zymogen activationGO:0031638410.052
response to insulinGO:00328681000.051
metaphase plate congressionGO:005131020.051
b cell differentiationGO:0030183780.051
actomyosin structure organizationGO:0031032560.051
sensory organ morphogenesisGO:00905962420.051
antibacterial peptide productionGO:000277820.051
auditory receptor cell fate determinationGO:004266830.050
positive regulation of antibacterial peptide biosynthetic processGO:000696310.050
cellular response to radiationGO:0071478280.050
cytokine productionGO:00018163190.050
ribonucleotide metabolic processGO:00092592910.050
regulation of antibacterial peptide biosynthetic processGO:000280810.050
epithelial tube morphogenesisGO:00605623030.050
ras protein signal transductionGO:0007265770.050
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.049
cellular response to acid chemicalGO:0071229680.049
regulation of cellular ketone metabolic processGO:0010565660.049
positive regulation of antimicrobial humoral responseGO:000276020.048
regulation of response to biotic stimulusGO:0002831380.048
protein polymerizationGO:0051258570.048
trophoblast giant cell differentiationGO:0060707150.048
positive regulation of cell divisionGO:0051781310.048
neuroblast proliferationGO:0007405490.048
positive regulation of mitotic cell cycle phase transitionGO:1901992170.048
regulation of lymphocyte apoptotic processGO:0070228410.047
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.047
purine ribonucleotide catabolic processGO:00091542080.046
signal transduction involved in mitotic dna integrity checkpointGO:190240330.046
signal transduction involved in mitotic dna damage checkpointGO:190240230.046
regulation of protein stabilityGO:0031647520.046
hormone secretionGO:00468791280.045
cleavage furrow formationGO:003608920.045
antimicrobial humoral responseGO:0019730110.045
Fly
aromatic compound catabolic processGO:00194392860.044
peptidyl tyrosine phosphorylationGO:00181081430.044
negative regulation of cell agingGO:009034450.044
signal transduction in absence of ligandGO:0038034550.044
developmental programmed cell deathGO:0010623410.044
Fly
protein localization to chromatinGO:007116830.044
circadian rhythmGO:00076231140.044
epithelial cell developmentGO:00020641590.044
Mouse
regulation of cytoskeleton organizationGO:00514931220.044
nucleoside metabolic processGO:00091162460.044
ovulation cycleGO:0042698590.044
protein localization to chromosome centromeric regionGO:007145910.044
regulation of mitotic sister chromatid segregationGO:0033047120.044
histone modificationGO:00165701590.043
hematopoietic progenitor cell differentiationGO:00022441430.043
positive regulation of protein serine threonine kinase activityGO:00719021060.043
cellular response to superoxideGO:0071451140.043
negative regulation of apoptotic signaling pathwayGO:20012341040.043
megakaryocyte differentiationGO:0030219260.042
regulation of chromatin organizationGO:1902275570.042
regulation of mitosisGO:0007088290.042
positive regulation of protein ubiquitinationGO:0031398270.042
metaphase anaphase transition of mitotic cell cycleGO:000709190.042
negative regulation of cell activationGO:00508661110.042
extracellular structure organizationGO:00430621480.041
cation transportGO:00068123990.041
epithelial cell proliferationGO:00506731740.041
negative regulation of leukocyte proliferationGO:0070664460.041
positive regulation of histone h3 k9 methylationGO:005157440.041
nucleobase containing small molecule metabolic processGO:00550863520.040
nucleotide metabolic processGO:00091173320.040
regulation of cellular response to growth factor stimulusGO:0090287820.040
nucleoside phosphate metabolic processGO:00067533380.040
stem cell differentiationGO:00488632680.040
regulation of antibacterial peptide productionGO:000278610.040
negative regulation of t cell proliferationGO:0042130380.040
purine nucleoside catabolic processGO:00061522050.040
cellularizationGO:000734910.040
mitotic sister chromatid separationGO:005130690.040
dna packagingGO:0006323300.040
amine metabolic processGO:0009308450.040
cellular response to cytokine stimulusGO:00713451890.040
nuclear dna replicationGO:003326030.040
regulation of chromatin silencingGO:003193520.040
cell growthGO:00160491300.039
positive regulation of protein modification by small protein conjugation or removalGO:1903322300.039
regulation of protein ubiquitinationGO:0031396520.038
reactive oxygen species metabolic processGO:0072593840.038
negative regulation of lymphocyte proliferationGO:0050672450.038
regulation of lipid metabolic processGO:00192161180.038
notch signaling pathwayGO:0007219710.038
positive regulation of cellular amino acid metabolic processGO:004576430.037
histone acetylationGO:0016573410.037
regulation of reproductive processGO:2000241660.037
Fly
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.037
regulation of antimicrobial humoral responseGO:000275930.037
camera type eye developmentGO:00430102660.037
cellular response to hormone stimulusGO:00328701500.037
tube closureGO:0060606910.037

E2f1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.419
cancerDOID:16200.130
organ system cancerDOID:005068600.104
thoracic cancerDOID:509300.064
immune system cancerDOID:006008300.060
gastrointestinal system cancerDOID:311900.055
breast cancerDOID:161200.047
large intestine cancerDOID:567200.044
intestinal cancerDOID:1015500.044
disease of metabolismDOID:001466700.037
inherited metabolic disorderDOID:65500.037
urinary system cancerDOID:399600.037