Mus musculus

0 known processes

Top1mt

DNA topoisomerase 1, mitochondrial

(Aliases: 2900052H09Rik)

Top1mt biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201030.088
transmembrane transportGO:00550854120.051
cellular nitrogen compound catabolic processGO:00442702800.048
aromatic compound catabolic processGO:00194392860.047
cellular ketone metabolic processGO:0042180840.046
positive regulation of cellular amine metabolic processGO:003324050.046
regulation of cellular ketone metabolic processGO:0010565660.045
positive regulation of cellular amino acid metabolic processGO:004576430.044
heterocycle catabolic processGO:00467002800.044
organonitrogen compound catabolic processGO:19015652640.044
purine ribonucleoside metabolic processGO:00461282410.043
cellular amine metabolic processGO:0044106440.043
organic cyclic compound catabolic processGO:19013612950.042
regulation of cellular amine metabolic processGO:0033238200.042
amine metabolic processGO:0009308450.041
regulation of cellular amino acid metabolic processGO:000652150.038
nucleobase containing small molecule metabolic processGO:00550863520.037
ribonucleoside metabolic processGO:00091192450.034
purine nucleoside metabolic processGO:00422782410.033
dna metabolic processGO:00062593030.033
glycosyl compound metabolic processGO:19016572460.033
purine nucleotide metabolic processGO:00061633020.032
oxidation reduction processGO:00551143420.032
nucleotide metabolic processGO:00091173320.032
purine containing compound metabolic processGO:00725213110.031
ion transmembrane transportGO:00342203610.031
nucleoside phosphate metabolic processGO:00067533380.031
regulation of membrane potentialGO:00423911920.031
mitochondrion organizationGO:00070051340.029
macromolecule catabolic processGO:00090572810.028
carbohydrate derivative catabolic processGO:19011362310.027
regulation of organelle organizationGO:00330432890.027
nucleoside metabolic processGO:00091162460.027
cytokine productionGO:00018163190.026
ribose phosphate metabolic processGO:00196932910.026
carbohydrate derivative biosynthetic processGO:19011371830.025
purine nucleoside catabolic processGO:00061522050.024
peptidyl amino acid modificationGO:00181933360.024
purine ribonucleoside catabolic processGO:00461302050.024
response to organonitrogen compoundGO:00102432460.024
ribonucleotide metabolic processGO:00092592910.023
cell type specific apoptotic processGO:00972852680.023
nitrogen compound transportGO:00717052710.023
negative regulation of protein metabolic processGO:00512482820.023
organonitrogen compound biosynthetic processGO:19015661920.023
nucleotide catabolic processGO:00091662170.022
nucleoside catabolic processGO:00091642060.022
spermatogenesisGO:00072832840.022
cellular response to dna damage stimulusGO:00069742070.022
cation transportGO:00068123990.022
cation transmembrane transportGO:00986552660.022
organic hydroxy compound metabolic processGO:19016152030.022
regulation of cytokine productionGO:00018172660.022
cytoplasmic transportGO:00164822340.022
regulation of cell activationGO:00508652890.022
purine ribonucleotide metabolic processGO:00091502900.022
ribonucleoside catabolic processGO:00424542060.022
male gamete generationGO:00482322850.022
purine ribonucleoside triphosphate metabolic processGO:00092052200.022
purine nucleotide catabolic processGO:00061952110.021
immune effector processGO:00022523210.021
apoptotic signaling pathwayGO:00971903060.021
cofactor metabolic processGO:0051186800.020
neuronal action potentialGO:0019228540.020
ribonucleoside triphosphate metabolic processGO:00091992200.020
carbohydrate metabolic processGO:00059752300.020
cofactor transportGO:005118140.020
intracellular protein transportGO:00068862040.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
inorganic cation transmembrane transportGO:00986622070.019
cellular homeostasisGO:00197252400.019
nucleoside triphosphate catabolic processGO:00091432050.019
purine containing compound catabolic processGO:00725232130.019
glycosyl compound catabolic processGO:19016582060.019
purine ribonucleotide catabolic processGO:00091542080.019
cell adhesionGO:00071553290.019
regulation of protein localizationGO:00328802310.019
cellular lipid metabolic processGO:00442553230.019
protein maturationGO:00516041760.018
cellular macromolecule catabolic processGO:00442652060.018
regulation of ion transportGO:00432692150.018
positive regulation of cell deathGO:00109422240.018
ribonucleotide catabolic processGO:00092612080.018
regulation of transferase activityGO:00513382630.018
transmission of nerve impulseGO:0019226760.018
regulation of establishment of protein localizationGO:00702011810.018
negative regulation of cellular protein metabolic processGO:00322692470.018
homeostasis of number of cellsGO:00488722100.018
nucleoside phosphate catabolic processGO:19012922220.018
protein localization to organelleGO:00333651850.017
posttranscriptional regulation of gene expressionGO:00106081550.017
gland developmentGO:00487323300.017
action potentialGO:0001508780.017
cellular metal ion homeostasisGO:00068751510.017
organophosphate catabolic processGO:00464342320.017
regulation of lymphocyte activationGO:00512492400.017
positive regulation of protein modification processGO:00314012990.017
metal ion homeostasisGO:00550651890.017
response to inorganic substanceGO:0010035960.017
response to organic cyclic compoundGO:00140701980.017
striated muscle tissue developmentGO:00147062930.017
reactive oxygen species metabolic processGO:0072593840.017
regulation of hormone levelsGO:00108172110.017
ribonucleoside triphosphate catabolic processGO:00092031990.017
small gtpase mediated signal transductionGO:0007264970.017
regulation of secretion by cellGO:19035302490.017
multicellular organismal signalingGO:0035637910.017
inorganic ion transmembrane transportGO:00986602340.016
g protein coupled receptor signaling pathwayGO:00071862430.016
protein processingGO:00164851630.016
anion transportGO:00068201770.016
cellular chemical homeostasisGO:00550822150.016
regulation of hydrolase activityGO:00513362460.016
nucleoside triphosphate metabolic processGO:00091412300.016
muscle tissue developmentGO:00605373080.016
positive regulation of protein phosphorylationGO:00019342420.015
anatomical structure homeostasisGO:00602491450.015
skin developmentGO:00435882200.015
cofactor biosynthetic processGO:0051188410.015
positive regulation of programmed cell deathGO:00430682180.015
muscle system processGO:00030121410.015
sensory perceptionGO:00076002450.015
leukocyte differentiationGO:00025213420.015
alpha amino acid metabolic processGO:1901605590.015
regulation of secretionGO:00510462740.015
nucleocytoplasmic transportGO:00069131390.015
regulation of system processGO:00440572000.015
negative regulation of phosphorus metabolic processGO:00105631840.015
organic acid biosynthetic processGO:0016053860.015
carboxylic acid biosynthetic processGO:0046394860.015
divalent inorganic cation transportGO:00725111780.015
t cell activationGO:00421102890.015
monosaccharide metabolic processGO:00059961060.015
cation homeostasisGO:00550802120.015
neuron apoptotic processGO:00514021420.015
regulation of apoptotic signaling pathwayGO:20012331970.015
membrane organizationGO:00610242450.014
myeloid cell differentiationGO:00300992330.014
synaptic transmissionGO:00072683290.014
cellular response to lipidGO:00713961450.014
intrinsic apoptotic signaling pathwayGO:00971931320.014
sulfur compound metabolic processGO:00067901000.014
positive regulation of apoptotic processGO:00430652170.014
regulation of kinase activityGO:00435492490.014
coenzyme metabolic processGO:0006732520.014
nuclear transportGO:00511691390.014
cellular response to organonitrogen compoundGO:00714171450.014
cellular carbohydrate metabolic processGO:00442621190.014
regulation of anatomical structure sizeGO:00900661780.014
response to radiationGO:00093141650.014
circulatory system processGO:00030131970.014
divalent metal ion transportGO:00708381720.014
alcohol metabolic processGO:00060661160.014
cellular ion homeostasisGO:00068731650.014
organic hydroxy compound transportGO:0015850930.013
regulation of transmembrane transportGO:00347621280.013
locomotory behaviorGO:00076261950.013
positive regulation of cell developmentGO:00107202370.013
regulation of defense responseGO:00313472330.013
inflammatory responseGO:00069542440.013
response to oxidative stressGO:00069791230.013
negative regulation of immune system processGO:00026832090.013
muscle cell differentiationGO:00426922610.013
organic anion transportGO:00157111370.013
positive regulation of cytokine productionGO:00018191740.013
protein targetingGO:00066051430.013
regulation of protein transportGO:00512231630.013
translationGO:0006412930.013
cell substrate adhesionGO:00315891300.013
fat cell differentiationGO:00454441600.013
lateral inhibitionGO:004633110.013
regulation of intracellular transportGO:00323861590.013
cellular protein complex assemblyGO:00436231160.013
neuron deathGO:00709971540.013
renal system developmentGO:00720012250.013
cellular response to hormone stimulusGO:00328701500.013
blood circulationGO:00080151950.013
chromatin organizationGO:00063252060.013
positive regulation of hydrolase activityGO:00513451480.012
epithelial tube morphogenesisGO:00605623030.012
calcium ion transportGO:00068161590.012
activation of immune responseGO:00022531380.012
protein catabolic processGO:00301632210.012
mapk cascadeGO:00001652810.012
macromolecule methylationGO:00434141200.012
regulation of homeostatic processGO:00328441820.012
negative regulation of protein modification processGO:00314001630.012
negative regulation of intracellular signal transductionGO:19025321670.012
organophosphate biosynthetic processGO:00904071220.012
cellular response to cytokine stimulusGO:00713451890.012
hexose metabolic processGO:0019318980.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.012
regulation of cellular catabolic processGO:00313292420.012
compound eye developmentGO:004874910.012
methylationGO:00322591340.012
regulation of response to woundingGO:19030341890.012
purine ribonucleoside triphosphate catabolic processGO:00092071990.012
negative regulation of molecular functionGO:00440922580.012
divalent inorganic cation homeostasisGO:00725071380.012
ras protein signal transductionGO:0007265770.012
negative regulation of phosphate metabolic processGO:00459361840.012
carboxylic acid transportGO:00469421000.012
establishment of protein localization to organelleGO:00725941180.012
regulation of neuron deathGO:19012141340.012
regulation of purine nucleotide metabolic processGO:19005421690.012
negative regulation of cellular component organizationGO:00511291940.012
multicellular organismal homeostasisGO:00488711640.012
hematopoietic progenitor cell differentiationGO:00022441430.012
protein importGO:00170381010.012
regulation of cell adhesionGO:00301551540.012
regulation of interleukin 8 productionGO:003267730.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
positive regulation of lymphocyte activationGO:00512511400.011
lymphocyte proliferationGO:00466511640.011
calcium ion homeostasisGO:00550741270.011
organic acid transportGO:00158491010.011
cellular modified amino acid metabolic processGO:0006575630.011
carbohydrate homeostasisGO:00335001280.011
rho protein signal transductionGO:0007266320.011
regulation of ion transmembrane transportGO:00347651190.011
lymphocyte differentiationGO:00300982420.011
regulation of translationGO:0006417710.011
regulation of cellular response to stressGO:00801351590.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
monocarboxylic acid metabolic processGO:00327871910.011
dephosphorylationGO:00163111290.011
response to lipopolysaccharideGO:00324961280.011
regulation of mapk cascadeGO:00434082480.011
regulation of cell motilityGO:20001452360.011
regulation of t cell activationGO:00508631700.011
response to molecule of bacterial originGO:00022371430.011
reactive nitrogen species metabolic processGO:200105700.011
cognitionGO:00508901490.011
glycoprotein metabolic processGO:00091001160.011
forebrain developmentGO:00309003020.011
regulation of protein kinase activityGO:00458592320.011
cellular calcium ion homeostasisGO:00068741190.011
regulation of neuron differentiationGO:00456642810.011
epithelial cell developmentGO:00020641590.011
response to acid chemicalGO:00011011110.011
purine nucleoside triphosphate catabolic processGO:00091462030.011
glucose homeostasisGO:00425931280.011
regulation of proteolysisGO:00301621640.011
adult behaviorGO:00305341350.011
regulation of inflammatory responseGO:00507271470.011
negative regulation of cell proliferationGO:00082852960.011
negative regulation of protein phosphorylationGO:00019331260.011
b cell activationGO:00421131610.011
negative regulation of phosphorylationGO:00423261660.010
wnt signaling pathwayGO:00160551880.010
carboxylic acid catabolic processGO:0046395510.010
epithelial cell proliferationGO:00506731740.010
innate immune responseGO:00450871570.010
nucleoside monophosphate metabolic processGO:0009123850.010
lipid biosynthetic processGO:00086101790.010
positive regulation of transferase activityGO:00513471670.010
interleukin 8 productionGO:003263740.010
tissue homeostasisGO:00018941150.010
regulation of neuron apoptotic processGO:00435231220.010
ribonucleoside bisphosphate metabolic processGO:003387590.010
negative regulation of cellular amino acid metabolic processGO:004576300.010
endomembrane system organizationGO:00102561470.010
regulation of cytoplasmic transportGO:19036491120.010
heart processGO:0003015940.010
response to oxygen levelsGO:0070482620.010
negative regulation of cellular amine metabolic processGO:003323910.010
sequestering of calcium ionGO:0051208180.010
urogenital system developmentGO:00016552610.010
amide transportGO:00428861380.010

Top1mt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.026
disease of anatomical entityDOID:700.026
disease of metabolismDOID:001466700.023
inherited metabolic disorderDOID:65500.017
central nervous system diseaseDOID:33100.014
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.012
cancerDOID:16200.012
musculoskeletal system diseaseDOID:1700.011
neurodegenerative diseaseDOID:128900.011
sensory system diseaseDOID:005015500.010
eye and adnexa diseaseDOID:149200.010
eye diseaseDOID:561400.010