Mus musculus

7 known processes

Aph1b

anterior pharynx defective 1b homolog (C. elegans)

(Aliases: Aph1c,2310057K14Rik)

Aph1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
purine nucleotide metabolic processGO:00061633020.141
nucleoside phosphate metabolic processGO:00067533380.133
nucleotide catabolic processGO:00091662170.105
organic cyclic compound catabolic processGO:19013612950.101
ribonucleoside metabolic processGO:00091192450.099
purine ribonucleotide metabolic processGO:00091502900.098
purine containing compound metabolic processGO:00725213110.092
nucleotide metabolic processGO:00091173320.092
ribonucleotide catabolic processGO:00092612080.089
purine nucleoside triphosphate metabolic processGO:00091442260.089
nucleoside phosphate catabolic processGO:19012922220.086
ribonucleoside triphosphate catabolic processGO:00092031990.084
heterocycle catabolic processGO:00467002800.079
carbohydrate derivative catabolic processGO:19011362310.078
purine ribonucleotide catabolic processGO:00091542080.072
glycosyl compound catabolic processGO:19016582060.072
organonitrogen compound catabolic processGO:19015652640.072
ribose phosphate metabolic processGO:00196932910.071
nucleobase containing small molecule metabolic processGO:00550863520.070
aromatic compound catabolic processGO:00194392860.069
nucleoside triphosphate metabolic processGO:00091412300.068
ribonucleotide metabolic processGO:00092592910.068
purine ribonucleoside triphosphate catabolic processGO:00092071990.062
purine ribonucleoside metabolic processGO:00461282410.061
purine ribonucleoside triphosphate metabolic processGO:00092052200.061
cellular nitrogen compound catabolic processGO:00442702800.061
ribonucleoside catabolic processGO:00424542060.060
purine containing compound catabolic processGO:00725232130.057
organophosphate catabolic processGO:00464342320.056
organelle localizationGO:00516401790.055
ribonucleoside triphosphate metabolic processGO:00091992200.055
regulation of membrane potentialGO:00423911920.054
purine nucleoside triphosphate catabolic processGO:00091462030.053
purine nucleoside metabolic processGO:00422782410.051
nucleoside metabolic processGO:00091162460.051
membrane organizationGO:00610242450.051
purine nucleotide catabolic processGO:00061952110.049
amine metabolic processGO:0009308450.047
purine nucleoside catabolic processGO:00061522050.047
regulation of cellular catabolic processGO:00313292420.046
cellular amino acid metabolic processGO:00065201030.046
regulation of cellular amine metabolic processGO:0033238200.045
nitrogen compound transportGO:00717052710.044
regulation of cellular amino acid metabolic processGO:000652150.044
response to organonitrogen compoundGO:00102432460.044
cellular homeostasisGO:00197252400.043
regulation of secretion by cellGO:19035302490.042
establishment of vesicle localizationGO:0051650810.042
cation transportGO:00068123990.041
establishment of organelle localizationGO:00516561220.041
transmembrane transportGO:00550854120.041
ras protein signal transductionGO:0007265770.041
nucleoside triphosphate catabolic processGO:00091432050.041
purine ribonucleoside catabolic processGO:00461302050.040
cation transmembrane transportGO:00986552660.040
regulation of nucleotide metabolic processGO:00061401690.040
nucleoside catabolic processGO:00091642060.039
small gtpase mediated signal transductionGO:0007264970.037
g protein coupled receptor signaling pathwayGO:00071862430.037
regulation of ion transportGO:00432692150.037
camera type eye developmentGO:00430102660.036
cellular amine metabolic processGO:0044106440.036
synaptic vesicle localizationGO:0097479590.035
action potentialGO:0001508780.034
inorganic cation transmembrane transportGO:00986622070.034
establishment of synaptic vesicle localizationGO:0097480570.034
cellular chemical homeostasisGO:00550822150.034
positive regulation of cellular amino acid metabolic processGO:004576430.034
positive regulation of cellular amine metabolic processGO:003324050.033
negative regulation of protein metabolic processGO:00512482820.033
forebrain developmentGO:00309003020.033
lipid biosynthetic processGO:00086101790.033
inorganic ion transmembrane transportGO:00986602340.033
cellular ketone metabolic processGO:0042180840.033
neurotransmitter transportGO:0006836760.033
response to light stimulusGO:00094161350.032
organic acid transportGO:00158491010.032
negative regulation of cellular protein metabolic processGO:00322692470.032
positive regulation of secretionGO:00510471300.032
multicellular organismal signalingGO:0035637910.032
sensory perceptionGO:00076002450.031
response to radiationGO:00093141650.031
cellular response to hormone stimulusGO:00328701500.031
regulation of cellular ketone metabolic processGO:0010565660.030
synaptic vesicle transportGO:0048489570.030
neuronal action potentialGO:0019228540.030
cellular response to lipidGO:00713961450.030
amino acid transportGO:0006865610.029
guanosine containing compound catabolic processGO:19010691440.029
negative regulation of cellular amino acid metabolic processGO:004576300.029
regulation of secretionGO:00510462740.029
negative regulation of nervous system developmentGO:00519611560.028
endomembrane system organizationGO:00102561470.028
response to peptideGO:19016521360.028
anion transportGO:00068201770.027
positive regulation of hydrolase activityGO:00513451480.027
macromolecule catabolic processGO:00090572810.027
fertilizationGO:00095661270.027
ion transmembrane transportGO:00342203610.027
glycosyl compound metabolic processGO:19016572460.026
negative regulation of cell developmentGO:00107211690.026
carbohydrate derivative biosynthetic processGO:19011371830.026
vesicle localizationGO:0051648860.026
negative regulation of molecular functionGO:00440922580.026
retina development in camera type eyeGO:00600411190.026
regulation of purine nucleotide metabolic processGO:19005421690.026
gtp catabolic processGO:00061841430.026
cellular ion homeostasisGO:00068731650.026
spermatogenesisGO:00072832840.026
oxidation reduction processGO:00551143420.025
cation homeostasisGO:00550802120.025
male gamete generationGO:00482322850.025
regionalizationGO:00030023370.025
positive regulation of cellular catabolic processGO:00313311480.025
neural tube developmentGO:00219151600.024
carboxylic acid transportGO:00469421000.024
positive regulation of secretion by cellGO:19035321140.024
posttranscriptional regulation of gene expressionGO:00106081550.024
cellular lipid metabolic processGO:00442553230.024
regulation of neurotransmitter levelsGO:0001505870.024
positive regulation of purine nucleotide metabolic processGO:19005441140.023
carbohydrate metabolic processGO:00059752300.023
lateral inhibitionGO:004633110.023
organophosphate biosynthetic processGO:00904071220.023
response to glycosideGO:190341620.023
organonitrogen compound biosynthetic processGO:19015661920.023
t cell activationGO:00421102890.023
potassium ion homeostasisGO:005507540.023
regulation of cell cycleGO:00517262810.023
gtp metabolic processGO:00460391440.023
cognitionGO:00508901490.023
telencephalon developmentGO:00215371860.023
regulation of gtp catabolic processGO:00331241130.022
apoptotic signaling pathwayGO:00971903060.022
regulation of hormone levelsGO:00108172110.022
guanosine containing compound metabolic processGO:19010681440.022
atp metabolic processGO:0046034750.022
organic acid biosynthetic processGO:0016053860.022
muscle system processGO:00030121410.022
cell type specific apoptotic processGO:00972852680.022
response to peptide hormoneGO:00434341270.022
synaptic transmissionGO:00072683290.021
sensory organ morphogenesisGO:00905962420.021
divalent metal ion transportGO:00708381720.021
limb morphogenesisGO:00351081490.021
muscle cell differentiationGO:00426922610.021
skeletal system developmentGO:00015013560.021
microtubule based processGO:00070172360.021
regulation of hydrolase activityGO:00513362460.021
regulation of kinase activityGO:00435492490.021
regulation of purine nucleotide catabolic processGO:00331211220.021
smoothened signaling pathwayGO:00072241050.021
developmental maturationGO:00217001930.021
protein catabolic processGO:00301632210.021
positive regulation of programmed cell deathGO:00430682180.021
dephosphorylationGO:00163111290.021
limb developmentGO:00601731660.021
negative regulation of phosphorus metabolic processGO:00105631840.020
regulation of system processGO:00440572000.020
regulation of protein kinase activityGO:00458592320.020
protein modification by small protein conjugation or removalGO:00706472070.020
regulation of nucleoside metabolic processGO:00091181300.020
positive regulation of nucleotide metabolic processGO:00459811140.020
respiratory system developmentGO:00605411900.020
organelle assemblyGO:00709251770.020
organic hydroxy compound metabolic processGO:19016152030.020
regulation of multi organism processGO:00439001110.020
nucleoside monophosphate metabolic processGO:0009123850.020
divalent inorganic cation homeostasisGO:00725071380.020
locomotory behaviorGO:00076261950.020
embryonic organ morphogenesisGO:00485622760.020
small molecule biosynthetic processGO:00442831320.020
negative regulation of cellular amine metabolic processGO:003323910.020
retrograde transport endosome to golgiGO:004214720.020
embryonic epithelial tube formationGO:00018381300.020
epithelial tube morphogenesisGO:00605623030.020
heart processGO:0003015940.020
blood circulationGO:00080151950.019
actin cytoskeleton organizationGO:00300362200.019
rho protein signal transductionGO:0007266320.019
endocytosisGO:00068971680.019
protein maturationGO:00516041760.019
Mouse
response to insulinGO:00328681000.019
positive regulation of ion transportGO:0043270650.019
fat cell differentiationGO:00454441600.019
exocytosisGO:00068871210.019
regulation of cell motilityGO:20001452360.018
regulation of cell migrationGO:00303342190.018
ribonucleoside monophosphate catabolic processGO:0009158570.018
inflammatory responseGO:00069542440.018
leukocyte differentiationGO:00025213420.018
organic hydroxy compound transportGO:0015850930.018
positive regulation of protein modification processGO:00314012990.018
positive regulation of purine nucleotide catabolic processGO:0033123880.018
carboxylic acid biosynthetic processGO:0046394860.018
regulation of transferase activityGO:00513382630.018
carbohydrate homeostasisGO:00335001280.018
digestive tract developmentGO:00485651900.018
Worm
asymmetric stem cell divisionGO:009872230.018
response to organic cyclic compoundGO:00140701980.018
monocarboxylic acid metabolic processGO:00327871910.017
heart morphogenesisGO:00030071780.017
cytoplasmic transportGO:00164822340.017
regulation of neuron differentiationGO:00456642810.017
multicellular organismal homeostasisGO:00488711640.017
purine nucleoside monophosphate catabolic processGO:0009128580.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.017
neural tube formationGO:00018411080.017
organic anion transportGO:00157111370.017
negative regulation of phosphate metabolic processGO:00459361840.017
ensheathment of neuronsGO:0007272760.017
cellular divalent inorganic cation homeostasisGO:00725031270.017
learning or memoryGO:00076111480.017
gland developmentGO:00487323300.017
ribonucleoside monophosphate metabolic processGO:0009161800.017
cell adhesionGO:00071553290.017
divalent inorganic cation transportGO:00725111780.017
axonogenesisGO:00074092740.017
heart contractionGO:0060047930.017
protein localization to plasma membraneGO:0072659570.017
negative regulation of cell proliferationGO:00082852960.017
plasma membrane organizationGO:0007009900.017
protein processingGO:00164851630.017
Mouse
positive regulation of nucleotide catabolic processGO:0030813880.017
muscle tissue developmentGO:00605373080.017
metal ion homeostasisGO:00550651890.017
calcium ion transportGO:00068161590.016
maintenance of locationGO:0051235890.016
cellular response to organonitrogen compoundGO:00714171450.016
modification dependent macromolecule catabolic processGO:00436321330.016
cellular metal ion homeostasisGO:00068751510.016
intracellular protein transportGO:00068862040.016
regulation of transmembrane transportGO:00347621280.016
positive regulation of cell developmentGO:00107202370.016
photoreceptor cell developmentGO:0042461400.016
substantia nigra developmentGO:002176220.016
photoreceptor cell differentiationGO:0046530520.016
purine ribonucleoside monophosphate metabolic processGO:0009167800.016
extrinsic apoptotic signaling pathwayGO:00971911260.016
negative regulation of protein modification processGO:00314001630.016
transmission of nerve impulseGO:0019226760.016
reactive oxygen species metabolic processGO:0072593840.015
alcohol metabolic processGO:00060661160.015
embryonic limb morphogenesisGO:00303261260.015
multi multicellular organism processGO:00447061090.015
positive regulation of nucleoside metabolic processGO:0045979910.015
protein localization to membraneGO:00726571080.015
circulatory system processGO:00030131970.015
regulation of anatomical structure sizeGO:00900661780.015
nucleoside phosphate biosynthetic processGO:1901293790.015
sodium ion transmembrane transportGO:0035725490.015
renal system developmentGO:00720012250.015
Mouse
mapk cascadeGO:00001652810.015
regulation of lymphocyte activationGO:00512492400.015
regulation of protein serine threonine kinase activityGO:00719001570.015
midgut developmentGO:000749440.015
vesicle organizationGO:0016050600.015
atp catabolic processGO:0006200550.015
myeloid leukocyte differentiationGO:00025731190.015
purine nucleoside monophosphate metabolic processGO:0009126810.015
compound eye developmentGO:004874910.015
cellular macromolecule catabolic processGO:00442652060.015
neuron deathGO:00709971540.015
regulation of apoptotic signaling pathwayGO:20012331970.015
regulation of vesicle mediated transportGO:00606271390.015
appendage morphogenesisGO:00351071490.015
peptide hormone secretionGO:00300721090.015
morphogenesis of a branching structureGO:00017632030.015
negative regulation of phosphorylationGO:00423261660.015
calcium ion homeostasisGO:00550741270.015
peptidyl amino acid modificationGO:00181933360.014
regulation of mapk cascadeGO:00434082480.014
regulation of cell activationGO:00508652890.014
negative regulation of protein phosphorylationGO:00019331260.014
regulation of nucleotide catabolic processGO:00308111220.014
regulation of ras protein signal transductionGO:00465781140.014
homeostasis of number of cellsGO:00488722100.014
response to lipopolysaccharideGO:00324961280.014
neurotransmitter secretionGO:0007269620.014
chromatin organizationGO:00063252060.014
positive regulation of apoptotic processGO:00430652170.014
hormone secretionGO:00468791280.014
negative regulation of cell cycleGO:00457861230.014
embryonic appendage morphogenesisGO:00351131260.014
regulation of cell morphogenesis involved in differentiationGO:00107691510.014
purine ribonucleoside monophosphate catabolic processGO:0009169570.014
striated muscle tissue developmentGO:00147062930.014
steroid metabolic processGO:00082021190.014
g protein coupled acetylcholine receptor signaling pathwayGO:000721340.014
carbohydrate transportGO:0008643620.014
tube formationGO:00351481400.014
adult locomotory behaviorGO:0008344910.014
protein targetingGO:00066051430.014
myelinationGO:0042552740.014
regulation of bindingGO:00510981110.014
oocyte constructionGO:000730820.014
negative regulation of hormone metabolic processGO:003235140.014
mitotic cell cycleGO:00002781950.014
positive regulation of nervous system developmentGO:00519622210.014
muscle contractionGO:00069361010.014
ossificationGO:00015032160.014
macromolecule glycosylationGO:0043413550.014
regulation of muscle system processGO:0090257800.014
peptide secretionGO:00027901140.014
cellular response to growth factor stimulusGO:00713631970.014
epithelial cell proliferationGO:00506731740.014
positive regulation of gtpase activityGO:0043547850.013
regulation of neuron deathGO:19012141340.013
hematopoietic progenitor cell differentiationGO:00022441430.013
dna metabolic processGO:00062593030.013
hexose transportGO:0008645560.013
calcium ion transmembrane transportGO:0070588850.013
protein modification by small protein conjugationGO:00324461870.013
adult behaviorGO:00305341350.013
neural precursor cell proliferationGO:00613511210.013
regulation of metal ion transportGO:00109591060.013
appendage developmentGO:00487361660.013
axon ensheathmentGO:0008366760.013
regulation of organelle organizationGO:00330432890.013
chemotaxisGO:00069352470.013
digestive system developmentGO:00551232000.013
Worm
axon target recognitionGO:000741240.013
positive regulation of gtp catabolic processGO:0033126850.013
mitotic cell cycle processGO:19030471590.013
vacuole organizationGO:0007033380.013
proteolysis involved in cellular protein catabolic processGO:00516031470.013
fatty acid metabolic processGO:00066311210.013
sodium ion transportGO:0006814730.013
cellular calcium ion homeostasisGO:00068741190.013
cilium morphogenesisGO:00602711020.013
amide transportGO:00428861380.013
regulation of blood circulationGO:1903522930.013
striated muscle contractionGO:0006941450.013
glucose homeostasisGO:00425931280.013
glucose transportGO:0015758560.013
positive regulation of apoptotic signaling pathwayGO:2001235950.013
protein ubiquitinationGO:00165671710.013
positive regulation of cell deathGO:00109422240.013
regulation of neuron projection developmentGO:00109751690.013
regulation of reproductive processGO:2000241660.013
phospholipid metabolic processGO:0006644870.013
myosin filament assemblyGO:003103420.013
regulation of glutamate secretionGO:001404830.013
negative regulation of hormone biosynthetic processGO:003235340.013
protein localization to organelleGO:00333651850.013
regulation of cellular response to stressGO:00801351590.013
nuclear divisionGO:00002801580.013
regulation of map kinase activityGO:00434051200.013
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.013
positive regulation of protein phosphorylationGO:00019342420.012
cellular response to lipopolysaccharideGO:0071222770.012
response to molecule of bacterial originGO:00022371430.012
second messenger mediated signalingGO:0019932730.012
regulation of feeding behaviorGO:006025930.012
regulation of protein stabilityGO:0031647520.012
regulation of mitotic cell cycleGO:00073461260.012
monosaccharide transportGO:0015749580.012
nucleotide biosynthetic processGO:0009165780.012
cellular response to extracellular stimulusGO:0031668810.012
cellular response to abiotic stimulusGO:0071214560.012
potassium ion transmembrane transportGO:0071805430.012
insulin secretionGO:0030073890.012
lymphocyte differentiationGO:00300982420.012
pallium developmentGO:00215431200.012
morphogenesis of embryonic epitheliumGO:00163311590.012
cellular protein complex assemblyGO:00436231160.012
regulation of synaptic plasticityGO:0048167870.012
cardiac muscle contractionGO:0060048320.012
glycoprotein metabolic processGO:00091001160.012
cellular protein catabolic processGO:00442571550.012
potassium ion transportGO:0006813520.012
pole plasm assemblyGO:000731520.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
regulation of protein catabolic processGO:00421761080.012
ear morphogenesisGO:00424711180.012
negative regulation of immune system processGO:00026832090.012
cellular response to external stimulusGO:0071496880.012
regulation of ion transmembrane transporter activityGO:0032412540.012
golgi to endosome transportGO:000689530.012
neuron apoptotic processGO:00514021420.012
dicarboxylic acid transportGO:0006835290.012
primary neural tube formationGO:0014020950.012
mitochondrion organizationGO:00070051340.012
purine containing compound biosynthetic processGO:0072522700.012
regulation of ion transmembrane transportGO:00347651190.012
response to growth factorGO:00708481980.012
lateral line system developmentGO:004892510.012
mitotic cytokinesisGO:000028140.012
cellular carbohydrate metabolic processGO:00442621190.012
lung developmentGO:00303241640.012
sensory system developmentGO:004888030.012
negative regulation of neuron differentiationGO:00456651010.012
regulation of homeostatic processGO:00328441820.012
sequestering of metal ionGO:0051238190.012
nucleoside monophosphate catabolic processGO:0009125590.012
negative regulation of cellular component organizationGO:00511291940.012
kidney developmentGO:00018222130.012
Mouse
regulation of protein localizationGO:00328802310.012
relaxation of muscleGO:0090075180.012
glycerophospholipid metabolic processGO:0006650710.011
glycoprotein biosynthetic processGO:0009101890.011
sensory perception of mechanical stimulusGO:00509541070.011
myeloid cell differentiationGO:00300992330.011
intracellular mrna localizationGO:000829840.011
developmental growth involved in morphogenesisGO:00605601380.011
response to nutrient levelsGO:00316671090.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.011
regulation of proteolysisGO:00301621640.011
wound healingGO:00420601570.011
cellular response to biotic stimulusGO:0071216920.011
regulation of defense responseGO:00313472330.011
leukocyte proliferationGO:00706611720.011
cellular response to organic cyclic compoundGO:0071407870.011
respiratory tube developmentGO:00303231670.011
rap protein signal transductionGO:003248630.011
rhodopsin mediated signaling pathwayGO:001605640.011
response to extracellular stimulusGO:00099911270.011
regulation of transporter activityGO:0032409570.011
acetylcholine transportGO:001587020.011
lipid transportGO:0006869980.011
cellular response to dna damage stimulusGO:00069742070.011
cellular response to molecule of bacterial originGO:0071219830.011
peptide transportGO:00158331330.011
morphogenesis of a branching epitheliumGO:00611381930.011
cellular component assembly involved in morphogenesisGO:00109271390.011
regulation of cellular component biogenesisGO:00440871810.011
maternal determination of anterior posterior axis embryoGO:000835820.011
sequestering of calcium ionGO:0051208180.011
purine nucleotide biosynthetic processGO:0006164650.011
nucleocytoplasmic transportGO:00069131390.011
memoryGO:0007613580.011
protein localization to nucleusGO:00345041210.011
cellular potassium ion transportGO:0071804430.011
glycosylationGO:0070085620.011
microtubule cytoskeleton organizationGO:00002261570.011
oocyte axis specificationGO:000730920.011
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.011
angiogenesisGO:00015252010.011
hormone metabolic processGO:0042445860.011
muscle cell developmentGO:00550011330.011
skeletal system morphogenesisGO:00487052030.011
regulation of neurotransmitter transportGO:0051588350.011
germ cell developmentGO:00072811850.011
Worm
blood vessel morphogenesisGO:00485142850.010
synapse organizationGO:00508081250.010
regulation of lipid metabolic processGO:00192161180.010
epidermis developmentGO:00085441870.010
modification dependent protein catabolic processGO:00199411330.010
positive regulation of neuron differentiationGO:00456661410.010
glycerolipid metabolic processGO:00464861220.010
cell maturationGO:00484691270.010
negative regulation of intracellular signal transductionGO:19025321670.010
spermatid developmentGO:00072861080.010
positive regulation of protein kinase activityGO:00458601440.010
regulation of protein processingGO:0070613960.010
regulation of synaptic growth at neuromuscular junctionGO:000858240.010
epithelial tube formationGO:00721751300.010
regulation of protein bindingGO:0043393600.010
connective tissue developmentGO:00614481790.010
cytokine productionGO:00018163190.010
sodium ion export from cellGO:003637610.010
regulation of neuron apoptotic processGO:00435231220.010
cell divisionGO:00513011200.010
bone developmentGO:00603481200.010
cerebellum developmentGO:0021549770.010
response to acid chemicalGO:00011011110.010
organelle fissionGO:00482851700.010
regulation of protein transportGO:00512231630.010
chromatin modificationGO:00165681870.010
regulation of actin filament based processGO:0032970990.010
ubiquitin dependent protein catabolic processGO:00065111290.010
spermatid differentiationGO:00485151150.010
inter male aggressive behaviorGO:000212130.010
positive regulation of protein export from nucleusGO:004682740.010
anatomical structure homeostasisGO:00602491450.010
regulation of cell cycle processGO:00105641600.010

Aph1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.075
nervous system diseaseDOID:86300.075
central nervous system diseaseDOID:33100.044
brain diseaseDOID:93600.020
disease of metabolismDOID:001466700.017
inherited metabolic disorderDOID:65500.015
immune system diseaseDOID:291400.014
sensory system diseaseDOID:005015500.014
neurodegenerative diseaseDOID:128900.012
eye and adnexa diseaseDOID:149200.012
disease of mental healthDOID:15000.011