Mus musculus

19 known processes

U2af2

U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2

(Aliases: MGC118033,65kDa)

U2af2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.324
mrna splicing via spliceosomeGO:0000398430.255
Human Fly
stem cell developmentGO:00488642190.175
establishment or maintenance of cytoskeleton polarityGO:003095220.169
stem cell differentiationGO:00488632680.163
mrna metabolic processGO:0016071840.151
Human Fly
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.104
Human Fly
regulation of mrna metabolic processGO:1903311430.097
Human Fly
nucleoside metabolic processGO:00091162460.096
purine nucleoside catabolic processGO:00061522050.086
rna splicing via transesterification reactionsGO:0000375430.085
Human Fly
regulation of organelle organizationGO:00330432890.076
Worm
small gtpase mediated signal transductionGO:0007264970.068
rna splicingGO:0008380540.068
cytoplasmic transportGO:00164822340.066
Fly
interspecies interaction between organismsGO:0044419830.063
regulation of synaptic growth at neuromuscular junctionGO:000858240.062
regulation of rna splicingGO:0043484370.062
Human Fly
chromatin modificationGO:00165681870.062
dna dealkylationGO:0035510110.062
dna methylationGO:0006306430.061
cellular amino acid metabolic processGO:00065201030.060
dna hypermethylationGO:004402630.059
negative regulation of cellular protein metabolic processGO:00322692470.058
regulation of cell cycleGO:00517262810.058
Worm
glycosyl compound metabolic processGO:19016572460.056
negative regulation of protein metabolic processGO:00512482820.056
posttranscriptional regulation of gene expressionGO:00106081550.055
histone methylationGO:0016571710.055
positive regulation of cellular amine metabolic processGO:003324050.053
protein catabolic processGO:00301632210.051
purine ribonucleoside triphosphate catabolic processGO:00092071990.051
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.050
amine metabolic processGO:0009308450.048
organonitrogen compound catabolic processGO:19015652640.048
positive regulation of cellular amino acid metabolic processGO:004576430.048
dna repairGO:00062811070.048
carbohydrate derivative catabolic processGO:19011362310.046
mrna processingGO:0006397630.046
Human Fly
rna interferenceGO:001624620.046
viral life cycleGO:0019058360.045
regulation of meiotic cell cycleGO:0051445340.045
Worm
proteasomal protein catabolic processGO:0010498980.045
regulation of kinase activityGO:00435492490.044
regulation of purine nucleotide metabolic processGO:19005421690.044
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.043
methylationGO:00322591340.043
stem cell fate specificationGO:004886630.043
nucleobase containing small molecule metabolic processGO:00550863520.043
leukocyte differentiationGO:00025213420.043
symbiosis encompassing mutualism through parasitismGO:0044403830.042
dna modificationGO:0006304500.042
macromolecule methylationGO:00434141200.042
primary mirna processingGO:003105310.041
cellular ketone metabolic processGO:0042180840.041
regulation of mrna processingGO:0050684410.041
Human Fly
chromatin organizationGO:00063252060.041
oocyte constructionGO:000730820.040
positive regulation of dna templated transcription elongationGO:003278620.040
covalent chromatin modificationGO:00165691630.039
cellular macromolecule catabolic processGO:00442652060.039
gene silencing by mirnaGO:0035195100.039
macromolecule catabolic processGO:00090572810.037
organonitrogen compound biosynthetic processGO:19015661920.037
response to organic cyclic compoundGO:00140701980.036
viral processGO:0016032410.036
stem cell maintenanceGO:00198271300.035
regulation of transcription during meiosisGO:005103710.035
purine ribonucleoside metabolic processGO:00461282410.035
nucleoside phosphate metabolic processGO:00067533380.034
negative regulation of viral processGO:0048525230.034
oocyte anterior posterior axis specificationGO:000731420.034
regulation of bindingGO:00510981110.033
positive regulation of organelle organizationGO:00106381280.033
regulation of cellular ketone metabolic processGO:0010565660.032
oocyte axis specificationGO:000730920.032
positive regulation of purine nucleotide metabolic processGO:19005441140.032
rna processingGO:00063961050.031
regulation of cellular catabolic processGO:00313292420.031
negative regulation of molecular functionGO:00440922580.031
multi multicellular organism processGO:00447061090.031
regulation of mrna splicing via spliceosomeGO:0048024320.029
Human Fly
regulation of multi organism processGO:00439001110.029
negative regulation of protein modification processGO:00314001630.028
negative regulation of cell developmentGO:00107211690.027
ribonucleotide catabolic processGO:00092612080.027
cellular amine metabolic processGO:0044106440.027
spermatogenesisGO:00072832840.027
negative regulation of phosphate metabolic processGO:00459361840.027
regulation of cell cycle processGO:00105641600.027
Worm
er nucleus signaling pathwayGO:0006984270.027
regulation of nucleotide metabolic processGO:00061401690.027
negative regulation of nervous system developmentGO:00519611560.026
ribonucleoside metabolic processGO:00091192450.026
organism emergence from protective structureGO:007168440.026
cellular response to cytokine stimulusGO:00713451890.026
fat cell differentiationGO:00454441600.026
regulation of protein kinase activityGO:00458592320.026
regulation of hormone levelsGO:00108172110.026
gonad developmentGO:00084061410.026
Worm
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.025
negative regulation of kinase activityGO:0033673810.025
ribose phosphate metabolic processGO:00196932910.025
nucleotide catabolic processGO:00091662170.025
cell divisionGO:00513011200.024
Worm
regulation of wnt signaling pathwayGO:00301111230.024
purine ribonucleotide metabolic processGO:00091502900.024
ribonucleotide metabolic processGO:00092592910.024
negative regulation of phosphorylationGO:00423261660.024
regulation of nuclear divisionGO:0051783560.024
Worm
purine containing compound metabolic processGO:00725213110.024
regulation of protein localizationGO:00328802310.023
microtubule based processGO:00070172360.023
Fly
regulation of cytoplasmic transportGO:19036491120.023
Fly
positive regulation of nucleotide metabolic processGO:00459811140.023
purine nucleoside metabolic processGO:00422782410.023
multicellular organism growthGO:00352641610.023
developmental growth involved in morphogenesisGO:00605601380.022
histone modificationGO:00165701590.022
regulation of cellular amino acid metabolic processGO:000652150.022
positive regulation of mrna processingGO:0050685160.022
positive regulation of protein modification processGO:00314012990.022
cell growthGO:00160491300.022
aromatic compound catabolic processGO:00194392860.022
positive regulation of mitotic metaphase anaphase transitionGO:004584220.022
negative regulation of phosphorus metabolic processGO:00105631840.022
vitamin d receptor signaling pathwayGO:007056120.022
positive regulation of cell deathGO:00109422240.022
ion transmembrane transportGO:00342203610.022
purine containing compound catabolic processGO:00725232130.022
cation transportGO:00068123990.021
circadian regulation of gene expressionGO:0032922480.021
regulation of protein bindingGO:0043393600.021
positive regulation of apoptotic processGO:00430652170.021
carbohydrate derivative biosynthetic processGO:19011371830.021
regulation of nucleoside metabolic processGO:00091181300.021
genetic imprintingGO:0071514270.021
cellular response to insulin stimulusGO:0032869780.021
histone deubiquitinationGO:001657820.021
nucleotide metabolic processGO:00091173320.021
male gamete generationGO:00482322850.021
cellular nitrogen compound catabolic processGO:00442702800.021
compound eye developmentGO:004874910.020
regulation of cellular response to stressGO:00801351590.020
chemotaxisGO:00069352470.020
connective tissue developmentGO:00614481790.020
cellular response to organic cyclic compoundGO:0071407870.020
response to peptide hormoneGO:00434341270.020
regulation of mitochondrion organizationGO:0010821270.020
positive regulation of cellular catabolic processGO:00313311480.020
olfactory learningGO:000835520.020
negative regulation of cell cycle processGO:0010948690.020
histone h3 k14 acetylationGO:004415430.020
locomotory behaviorGO:00076261950.020
gene silencingGO:0016458380.020
habituationGO:004695930.020
purine ribonucleoside catabolic processGO:00461302050.019
mitotic cell cycle processGO:19030471590.019
Fly
regulation of cell cycle phase transitionGO:1901987770.019
positive regulation of programmed cell deathGO:00430682180.019
regulation of establishment of protein localizationGO:00702011810.019
regulation of protein stabilityGO:0031647520.019
regulation of cellular amine metabolic processGO:0033238200.019
chromatin disassemblyGO:003149810.019
signal transduction in absence of ligandGO:0038034550.019
positive regulation of cell cycleGO:0045787920.019
negative regulation of cell proliferationGO:00082852960.019
regulation of protein transportGO:00512231630.019
development of primary sexual characteristicsGO:00451371430.018
Worm
regulation of secretion by cellGO:19035302490.018
homeostasis of number of cellsGO:00488722100.018
organic cyclic compound catabolic processGO:19013612950.018
regulation of intracellular transportGO:00323861590.018
Fly
nuclear transportGO:00511691390.018
Fly
maternal determination of anterior posterior axis embryoGO:000835820.018
regulation of nucleotide catabolic processGO:00308111220.018
cognitionGO:00508901490.018
ribonucleoside triphosphate metabolic processGO:00091992200.018
positive regulation of gtpase activityGO:0043547850.018
demethylationGO:0070988230.018
heterocycle catabolic processGO:00467002800.018
histone lysine methylationGO:0034968500.018
male meiosis iGO:0007141160.018
canonical wnt signaling pathwayGO:00600701300.018
localization within membraneGO:005166840.018
regulation of secretionGO:00510462740.018
receptor mediated endocytosisGO:0006898510.017
regulation of histone modificationGO:0031056560.017
regulation of ras protein signal transductionGO:00465781140.017
alternative mrna splicing via spliceosomeGO:0000380120.017
Fly
cell maturationGO:00484691270.017
protein ubiquitinationGO:00165671710.017
purine nucleotide metabolic processGO:00061633020.017
guanosine containing compound catabolic processGO:19010691440.017
negative regulation of transferase activityGO:0051348850.017
meiotic nuclear divisionGO:00071261150.017
Worm
oogenesisGO:0048477560.017
transdifferentiationGO:006029010.017
protein methylationGO:0006479810.017
endocytosisGO:00068971680.017
positive regulation of growthGO:00459271040.017
nucleoside catabolic processGO:00091642060.017
regulation of cellular component biogenesisGO:00440871810.017
hatchingGO:003518840.017
mitotic cell cycleGO:00002781950.017
Fly
transcription coupled nucleotide excision repairGO:000628320.016
wnt signaling pathwayGO:00160551880.016
positive regulation of cell cycle processGO:0090068610.016
metal ion homeostasisGO:00550651890.016
positive regulation of protein phosphorylationGO:00019342420.016
segmentationGO:0035282930.016
peptidyl amino acid modificationGO:00181933360.016
dephosphorylationGO:00163111290.016
small molecule biosynthetic processGO:00442831320.016
muscle tissue developmentGO:00605373080.016
positive regulation of dna repairGO:004573930.016
dsrna fragmentationGO:003105060.016
ribonucleoside catabolic processGO:00424542060.016
pole plasm assemblyGO:000731520.016
purine nucleoside triphosphate metabolic processGO:00091442260.016
skeletal system developmentGO:00015013560.016
regulation of muscle tissue developmentGO:1901861970.015
positive regulation of nervous system developmentGO:00519622210.015
transmembrane transportGO:00550854120.015
mesenchyme developmentGO:00604851520.015
regulation of purine nucleotide catabolic processGO:00331211220.015
microtubule cytoskeleton organizationGO:00002261570.015
Fly
intracellular receptor signaling pathwayGO:0030522740.015
male sex differentiationGO:00466611090.015
regulation of transferase activityGO:00513382630.015
regulation of mapk cascadeGO:00434082480.015
nuclear exportGO:0051168340.015
Fly
regulation of protein catabolic processGO:00421761080.015
nucleobase containing compound transportGO:0015931270.015
Fly
germ cell developmentGO:00072811850.015
Worm
regulation of cell divisionGO:0051302760.015
Worm
purine ribonucleoside triphosphate metabolic processGO:00092052200.015
mitochondrion organizationGO:00070051340.015
glucose homeostasisGO:00425931280.014
cellular homeostasisGO:00197252400.014
negative regulation of peroxisome proliferator activated receptor signaling pathwayGO:003535930.014
cellular protein catabolic processGO:00442571550.014
heart contractionGO:0060047930.014
peptide hormone secretionGO:00300721090.014
negative regulation of multi organism processGO:0043901680.014
calcium mediated signalingGO:0019722460.014
chromatin assembly or disassemblyGO:0006333160.014
rhythmic processGO:00485111740.014
carboxylic acid biosynthetic processGO:0046394860.014
modification dependent macromolecule catabolic processGO:00436321330.014
hormone secretionGO:00468791280.014
retrograde transport endosome to golgiGO:004214720.014
negative regulation of gene expression epigeneticGO:0045814150.014
development of primary male sexual characteristicsGO:0046546880.014
developmental maturationGO:00217001930.014
regulation of circadian rhythmGO:0042752580.014
regulation of viral release from host cellGO:190218660.014
negative regulation of mrna processingGO:0050686120.014
Human
neuroblast differentiationGO:001401620.014
production of mirnas involved in gene silencing by mirnaGO:003519660.014
cellular response to vitamin dGO:007130520.013
regulation of adrenergic receptor signaling pathwayGO:007187740.013
positive regulation of hydrolase activityGO:00513451480.013
adult behaviorGO:00305341350.013
regulation of proteasomal protein catabolic processGO:0061136460.013
embryonic organ morphogenesisGO:00485622760.013
cellular response to hormone stimulusGO:00328701500.013
lipid biosynthetic processGO:00086101790.013
protein modification by small protein conjugationGO:00324461870.013
striated muscle tissue developmentGO:00147062930.013
mrna transportGO:0051028130.013
regulation of mitotic cell cycle phase transitionGO:1901990730.013
protein modification by small protein conjugation or removalGO:00706472070.013
mapk cascadeGO:00001652810.013
cation homeostasisGO:00550802120.013
positive regulation of purine nucleotide catabolic processGO:0033123880.013
peptide secretionGO:00027901140.013
negative regulation of synapse assemblyGO:005196430.013
regulation of nucleocytoplasmic transportGO:0046822730.012
Fly
maintenance of locationGO:0051235890.012
negative regulation of cellular component organizationGO:00511291940.012
protein targetingGO:00066051430.012
viral gene expressionGO:001908030.012
organophosphate catabolic processGO:00464342320.012
histone h3 acetylationGO:0043966140.012
carbohydrate metabolic processGO:00059752300.012
engulfment of apoptotic cellGO:004365230.012
translationGO:0006412930.012
ras protein signal transductionGO:0007265770.012
establishment of rna localizationGO:0051236180.012
Fly
positive regulation of cell cycle phase transitionGO:1901989170.012
regulation of hydrolase activityGO:00513362460.012
t cell activationGO:00421102890.012
blastocyst developmentGO:0001824800.012
nucleoside phosphate catabolic processGO:19012922220.012
axonogenesisGO:00074092740.012
response to insulinGO:00328681000.012
adult locomotory behaviorGO:0008344910.012
mesenchymal cell developmentGO:0014031930.012
chromatin assemblyGO:0031497130.012
lymphocyte differentiationGO:00300982420.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.012
regulation of protein complex assemblyGO:0043254830.012
protein secretionGO:00093061110.012
hematopoietic progenitor cell differentiationGO:00022441430.012
regulation of nucleotide biosynthetic processGO:0030808340.012
neuron apoptotic processGO:00514021420.011
organophosphate biosynthetic processGO:00904071220.011
circadian rhythmGO:00076231140.011
cellular response to peptide hormone stimulusGO:0071375920.011
histone h3 k9 dimethylationGO:003612340.011
intracellular protein transportGO:00068862040.011
modification dependent protein catabolic processGO:00199411330.011
histone deacetylationGO:0016575260.011
nucleoside triphosphate metabolic processGO:00091412300.011
mesenchymal cell differentiationGO:00487621070.011
negative regulation of cell growth involved in cardiac muscle cell developmentGO:006105220.011
learningGO:0007612980.011
regulation of cellular protein catabolic processGO:1903362610.011
cellular response to dna damage stimulusGO:00069742070.011
bone developmentGO:00603481200.011
regulation of gtp catabolic processGO:00331241130.011
regulation of translationGO:0006417710.011
multicellular organismal homeostasisGO:00488711640.011
response to drugGO:0042493750.011
regulation of organ morphogenesisGO:20000271440.011
regulation of system processGO:00440572000.011
positive regulation of nucleoside metabolic processGO:0045979910.011
purine nucleoside triphosphate catabolic processGO:00091462030.011
cell recognitionGO:0008037830.011
purine ribonucleotide catabolic processGO:00091542080.011
protein localization to nucleusGO:00345041210.011
negative regulation of organelle organizationGO:0010639900.011
neuron projection guidanceGO:00974851410.011
myeloid leukocyte differentiationGO:00025731190.011
cell cycle checkpointGO:0000075470.011
hypermethylation of cpg islandGO:004402730.010
immunoglobulin secretion involved in immune responseGO:000238020.010
spliceosomal complex assemblyGO:000024560.010
skeletal system morphogenesisGO:00487052030.010
blastocyst growthGO:0001832230.010
regulation of protein serine threonine kinase activityGO:00719001570.010
regulation of ion transmembrane transportGO:00347651190.010
positive regulation of mitotic cell cycleGO:0045931410.010
cartilage development involved in endochondral bone morphogenesisGO:0060351240.010
regulation of transmembrane transportGO:00347621280.010
calcium ion transportGO:00068161590.010
response to peptideGO:19016521360.010
genitalia developmentGO:0048806370.010
Worm
actin cytoskeleton organizationGO:00300362200.010
immune effector processGO:00022523210.010
peptide transportGO:00158331330.010
gtp metabolic processGO:00460391440.010
positive regulation of chromosome organizationGO:2001252330.010

U2af2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.013
nervous system diseaseDOID:86300.013
central nervous system diseaseDOID:33100.013
neurodegenerative diseaseDOID:128900.011
disease of cellular proliferationDOID:1456600.011
organ system cancerDOID:005068600.011
intestinal cancerDOID:1015500.011
gastrointestinal system cancerDOID:311900.011
cancerDOID:16200.011
eye diseaseDOID:561400.011
retinal diseaseDOID:567900.011
retinal degenerationDOID:846600.011
sensory system diseaseDOID:005015500.011
eye and adnexa diseaseDOID:149200.011