Mus musculus

0 known processes

Mcoln1

mucolipin 1

(Aliases: 2210015I05Rik,TRPML1,mucolipidin,MGC7172)

Mcoln1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane transportGO:00550854120.201
Fly
cation transportGO:00068123990.109
Fly
glycosyl compound catabolic processGO:19016582060.105
organonitrogen compound catabolic processGO:19015652640.103
ion transmembrane transportGO:00342203610.097
Fly
nucleoside phosphate metabolic processGO:00067533380.096
vacuole organizationGO:0007033380.094
Worm
cellular nitrogen compound catabolic processGO:00442702800.092
nucleoside triphosphate catabolic processGO:00091432050.091
nucleoside triphosphate metabolic processGO:00091412300.090
purine nucleoside catabolic processGO:00061522050.087
ribonucleotide catabolic processGO:00092612080.085
nucleotide catabolic processGO:00091662170.084
aromatic compound catabolic processGO:00194392860.084
nucleoside metabolic processGO:00091162460.083
organic cyclic compound catabolic processGO:19013612950.081
purine nucleotide metabolic processGO:00061633020.077
ribonucleotide metabolic processGO:00092592910.075
ribonucleoside metabolic processGO:00091192450.075
purine nucleotide catabolic processGO:00061952110.074
purine ribonucleoside catabolic processGO:00461302050.073
purine ribonucleoside triphosphate catabolic processGO:00092071990.072
purine ribonucleoside triphosphate metabolic processGO:00092052200.070
cation transmembrane transportGO:00986552660.070
Fly
lysosome organizationGO:0007040210.068
Worm
ribonucleoside triphosphate catabolic processGO:00092031990.067
organophosphate catabolic processGO:00464342320.067
ribonucleoside triphosphate metabolic processGO:00091992200.066
inorganic ion transmembrane transportGO:00986602340.066
purine nucleoside metabolic processGO:00422782410.065
inorganic cation transmembrane transportGO:00986622070.064
nucleobase containing small molecule metabolic processGO:00550863520.063
purine ribonucleotide metabolic processGO:00091502900.063
amine metabolic processGO:0009308450.062
carbohydrate derivative catabolic processGO:19011362310.060
nucleoside catabolic processGO:00091642060.059
glycosyl compound metabolic processGO:19016572460.058
purine ribonucleotide catabolic processGO:00091542080.057
regulation of cellular amino acid metabolic processGO:000652150.057
heterocycle catabolic processGO:00467002800.057
purine containing compound catabolic processGO:00725232130.056
muscle system processGO:00030121410.056
lytic vacuole organizationGO:0080171210.056
Worm
nucleotide metabolic processGO:00091173320.055
nucleoside phosphate catabolic processGO:19012922220.055
cellular amino acid metabolic processGO:00065201030.055
cellular homeostasisGO:00197252400.054
Fly
cellular amine metabolic processGO:0044106440.054
lipid biosynthetic processGO:00086101790.053
purine nucleoside triphosphate catabolic processGO:00091462030.052
regulation of cellular amine metabolic processGO:0033238200.052
ras protein signal transductionGO:0007265770.051
ribose phosphate metabolic processGO:00196932910.051
protein localization to organelleGO:00333651850.050
striated muscle contractionGO:0006941450.050
regulation of membrane potentialGO:00423911920.049
regulation of vesicle mediated transportGO:00606271390.048
Worm
membrane organizationGO:00610242450.046
Fly
ribonucleoside catabolic processGO:00424542060.045
nitrogen compound transportGO:00717052710.045
endocytosisGO:00068971680.043
Worm
learning or memoryGO:00076111480.042
protein ubiquitinationGO:00165671710.040
cytoplasmic transportGO:00164822340.040
response to glycosideGO:190341620.040
purine nucleoside triphosphate metabolic processGO:00091442260.040
regulation of ion transportGO:00432692150.039
regulation of organelle organizationGO:00330432890.039
response to light stimulusGO:00094161350.039
multicellular organismal homeostasisGO:00488711640.038
cardiac muscle cell contractionGO:008600370.038
muscle contractionGO:00069361010.038
synaptic transmissionGO:00072683290.038
protein modification by small protein conjugationGO:00324461870.037
protein modification by small protein conjugation or removalGO:00706472070.037
locomotory behaviorGO:00076261950.037
Mouse
cellular ketone metabolic processGO:0042180840.037
regulation of system processGO:00440572000.037
regulation of cellular ketone metabolic processGO:0010565660.036
anatomical structure homeostasisGO:00602491450.036
cation homeostasisGO:00550802120.036
Fly
purine containing compound metabolic processGO:00725213110.035
regulation of neuron differentiationGO:00456642810.035
establishment of vesicle localizationGO:0051650810.035
nucleoside monophosphate metabolic processGO:0009123850.034
intracellular protein transportGO:00068862040.034
macromolecule catabolic processGO:00090572810.034
regulation of anatomical structure sizeGO:00900661780.033
ventricular cardiac muscle cell action potentialGO:008600540.033
sensory perceptionGO:00076002450.033
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.033
anion transportGO:00068201770.032
negative regulation of cellular component organizationGO:00511291940.032
negative regulation of molecular functionGO:00440922580.032
regulation of synaptic growth at neuromuscular junctionGO:000858240.031
positive regulation of protein modification processGO:00314012990.031
guanosine containing compound metabolic processGO:19010681440.031
positive regulation of cellular amino acid metabolic processGO:004576430.031
ribonucleoside monophosphate metabolic processGO:0009161800.031
purine ribonucleoside metabolic processGO:00461282410.031
regulation of secretion by cellGO:19035302490.030
action potentialGO:0001508780.030
cell type specific apoptotic processGO:00972852680.029
g protein coupled receptor signaling pathwayGO:00071862430.029
negative regulation of protein metabolic processGO:00512482820.029
regulation of nucleoside metabolic processGO:00091181300.029
vesicle organizationGO:0016050600.029
heart morphogenesisGO:00030071780.029
actin cytoskeleton organizationGO:00300362200.028
visual behaviorGO:0007632450.028
regulation of secretionGO:00510462740.028
cellular divalent inorganic cation homeostasisGO:00725031270.027
Fly
microtubule based processGO:00070172360.027
organic hydroxy compound metabolic processGO:19016152030.027
cardiac muscle contractionGO:0060048320.026
oxidation reduction processGO:00551143420.026
metal ion homeostasisGO:00550651890.026
Fly
positive regulation of organelle organizationGO:00106381280.026
positive regulation of hydrolase activityGO:00513451480.026
regulation of protein localizationGO:00328802310.025
regulation of cytokine productionGO:00018172660.025
neuron apoptotic processGO:00514021420.025
sphingolipid metabolic processGO:0006665450.025
steroid metabolic processGO:00082021190.025
positive regulation of cellular amine metabolic processGO:003324050.025
cellular lipid metabolic processGO:00442553230.025
tissue homeostasisGO:00018941150.025
establishment of organelle localizationGO:00516561220.025
apoptotic signaling pathwayGO:00971903060.024
calcium ion homeostasisGO:00550741270.024
Fly
response to radiationGO:00093141650.024
hydrogen ion transmembrane transportGO:1902600250.024
cellular metal ion homeostasisGO:00068751510.024
Fly
posttranscriptional regulation of gene expressionGO:00106081550.024
regulation of transferase activityGO:00513382630.024
establishment of synaptic vesicle localizationGO:0097480570.024
potassium ion transmembrane transportGO:0071805430.024
regulation of cellular catabolic processGO:00313292420.023
positive regulation of programmed cell deathGO:00430682180.023
positive regulation of protein phosphorylationGO:00019342420.023
endomembrane system organizationGO:00102561470.023
negative regulation of cellular amino acid metabolic processGO:004576300.023
regulation of purine nucleotide metabolic processGO:19005421690.023
organelle localizationGO:00516401790.023
heart processGO:0003015940.023
regulation of hydrolase activityGO:00513362460.023
vesicle localizationGO:0051648860.023
cognitionGO:00508901490.023
synapse organizationGO:00508081250.022
skeletal system developmentGO:00015013560.022
glycerolipid metabolic processGO:00464861220.022
protein localization to membraneGO:00726571080.022
cellular potassium ion transportGO:0071804430.022
organonitrogen compound biosynthetic processGO:19015661920.022
regulation of blood circulationGO:1903522930.022
negative regulation of cellular amine metabolic processGO:003323910.021
protein catabolic processGO:00301632210.021
nucleoside monophosphate catabolic processGO:0009125590.021
carbohydrate metabolic processGO:00059752300.021
retrograde transport endosome to golgiGO:004214720.021
cellular response to growth factor stimulusGO:00713631970.021
regulation of kinase activityGO:00435492490.021
regulation of neuron apoptotic processGO:00435231220.021
regulation of neuron projection developmentGO:00109751690.021
positive regulation of cell developmentGO:00107202370.021
sodium ion transportGO:0006814730.021
cellular ion homeostasisGO:00068731650.021
Fly
negative regulation of nervous system developmentGO:00519611560.020
potassium ion transportGO:0006813520.020
microtubule based transportGO:0010970500.020
cellular chemical homeostasisGO:00550822150.020
Fly
retina development in camera type eyeGO:00600411190.020
regulation of hormone levelsGO:00108172110.020
regulation of cell cycleGO:00517262810.020
dephosphorylationGO:00163111290.020
chromatin modificationGO:00165681870.020
neuron deathGO:00709971540.020
phospholipid transfer to membraneGO:000664920.019
regulation of nucleotide metabolic processGO:00061401690.019
reactive oxygen species metabolic processGO:0072593840.019
regulation of neuron deathGO:19012141340.019
regulation of gtp catabolic processGO:00331241130.019
regulation of intracellular transportGO:00323861590.019
regulation of protein kinase activityGO:00458592320.019
cellular response to lipidGO:00713961450.019
organelle fusionGO:0048284280.019
Fly
response to organic cyclic compoundGO:00140701980.019
regulation of establishment of protein localizationGO:00702011810.019
regulation of cardiac muscle contractionGO:0055117210.019
atp metabolic processGO:0046034750.019
regulation of heart contractionGO:0008016770.019
regulation of cellular component biogenesisGO:00440871810.019
membrane lipid biosynthetic processGO:0046467320.019
multicellular organism growthGO:00352641610.019
positive regulation of secretionGO:00510471300.019
muscle cell differentiationGO:00426922610.019
divalent inorganic cation transportGO:00725111780.019
regulation of cell motilityGO:20001452360.018
rab protein signal transductionGO:003248210.018
positive regulation of nucleotide metabolic processGO:00459811140.018
cellular response to cytokine stimulusGO:00713451890.018
alcohol metabolic processGO:00060661160.018
synaptic vesicle localizationGO:0097479590.018
visual learningGO:0008542440.018
cellular response to hormone stimulusGO:00328701500.018
regulation of homeostatic processGO:00328441820.018
organic anion transportGO:00157111370.018
negative regulation of phosphate metabolic processGO:00459361840.017
divalent inorganic cation homeostasisGO:00725071380.017
Fly
sequestering of metal ionGO:0051238190.017
nuclear transportGO:00511691390.017
positive regulation of gtp catabolic processGO:0033126850.017
organic hydroxy compound transportGO:0015850930.017
peptide transportGO:00158331330.017
regulation of mapk cascadeGO:00434082480.017
blood circulationGO:00080151950.017
macroautophagyGO:0016236210.017
Fly
mapk cascadeGO:00001652810.017
hydrogen transportGO:0006818350.017
carbohydrate derivative biosynthetic processGO:19011371830.017
response to organonitrogen compoundGO:00102432460.017
transmission of nerve impulseGO:0019226760.017
synaptic vesicle transportGO:0048489570.017
negative regulation of cell proliferationGO:00082852960.016
positive regulation of transferase activityGO:00513471670.016
telencephalon developmentGO:00215371860.016
positive regulation of nucleotide catabolic processGO:0030813880.016
positive regulation of nucleoside metabolic processGO:0045979910.016
cytokine productionGO:00018163190.016
lipid transportGO:0006869980.016
Worm
positive regulation of apoptotic processGO:00430652170.016
organelle fissionGO:00482851700.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.016
cellular component assembly involved in morphogenesisGO:00109271390.016
organic acid transportGO:00158491010.016
regulation of metal ion transportGO:00109591060.016
regulation of lymphocyte activationGO:00512492400.016
germ cell developmentGO:00072811850.016
neuronal action potentialGO:0019228540.015
pigmentationGO:0043473710.015
neuron migrationGO:00017641220.015
ossificationGO:00015032160.015
protein targetingGO:00066051430.015
histone modificationGO:00165701590.015
regulation of purine nucleotide catabolic processGO:00331211220.015
embryonic organ morphogenesisGO:00485622760.015
ribonucleoside monophosphate catabolic processGO:0009158570.015
amide transportGO:00428861380.015
camera type eye developmentGO:00430102660.015
intrinsic apoptotic signaling pathwayGO:00971931320.015
plasma membrane organizationGO:0007009900.015
forebrain developmentGO:00309003020.015
small gtpase mediated signal transductionGO:0007264970.015
carboxylic acid transportGO:00469421000.015
response to extracellular stimulusGO:00099911270.015
Fly
organophosphate biosynthetic processGO:00904071220.015
glycerophospholipid metabolic processGO:0006650710.015
purine ribonucleoside monophosphate metabolic processGO:0009167800.015
respiratory system developmentGO:00605411900.014
regulation of ras gtpase activityGO:0032318880.014
associative learningGO:0008306610.014
peptidyl amino acid modificationGO:00181933360.014
sensory system developmentGO:004888030.014
regulation of nucleotide catabolic processGO:00308111220.014
monocarboxylic acid metabolic processGO:00327871910.014
membrane lipid metabolic processGO:0006643530.014
small molecule biosynthetic processGO:00442831320.014
proton transportGO:0015992350.014
negative regulation of cell developmentGO:00107211690.014
neurotransmitter transportGO:0006836760.014
response to molecule of bacterial originGO:00022371430.014
heart contractionGO:0060047930.014
synapse assemblyGO:0007416560.014
engulfment of apoptotic cellGO:004365230.014
negative regulation of organelle organizationGO:0010639900.014
response to nutrient levelsGO:00316671090.014
Fly
erk1 and erk2 cascadeGO:0070371770.014
divalent metal ion transportGO:00708381720.014
regulation of cytoskeleton organizationGO:00514931220.014
gtp catabolic processGO:00061841430.014
neural tube developmentGO:00219151600.014
lipoprotein metabolic processGO:0042157430.014
peptide hormone secretionGO:00300721090.014
dna metabolic processGO:00062593030.014
nuclear importGO:0051170950.014
embryonic epithelial tube formationGO:00018381300.014
homeostasis of number of cellsGO:00488722100.014
neuron neuron synaptic transmissionGO:0007270690.014
protein maturationGO:00516041760.014
sensory organ morphogenesisGO:00905962420.014
regulation of muscle contractionGO:0006937490.014
sphingosine 1 phosphate signaling pathwayGO:000337630.014
establishment of protein localization to organelleGO:00725941180.014
purine nucleoside monophosphate metabolic processGO:0009126810.013
regulation of actin filament based processGO:0032970990.013
skin developmentGO:00435882200.013
Mouse
peptide secretionGO:00027901140.013
skeletal muscle organ developmentGO:00605381630.013
gtp metabolic processGO:00460391440.013
striated muscle tissue developmentGO:00147062930.013
regulation of vacuole organizationGO:004408840.013
learningGO:0007612980.013
purine nucleoside monophosphate catabolic processGO:0009128580.013
positive regulation of striated muscle contractionGO:004598930.013
respiratory gaseous exchangeGO:0007585430.013
chromatin organizationGO:00063252060.013
gliogenesisGO:00420631410.013
amino acid transportGO:0006865610.013
regulation of cell growthGO:0001558910.013
gland developmentGO:00487323300.013
organelle assemblyGO:00709251770.013
positive regulation of gtpase activityGO:0043547850.013
negative regulation of synapse assemblyGO:005196430.013
regulation of cell activationGO:00508652890.013
hematopoietic progenitor cell differentiationGO:00022441430.013
negative regulation of phosphorus metabolic processGO:00105631840.013
circulatory system processGO:00030131970.013
actin filament based movementGO:0030048230.013
chemotaxisGO:00069352470.013
negative regulation of protein modification processGO:00314001630.013
regulation of reactive oxygen species metabolic processGO:2000377400.013
reactive nitrogen species metabolic processGO:200105700.013
positive regulation of protein kinase activityGO:00458601440.013
central nervous system neuron differentiationGO:00219531620.012
sequestering of calcium ionGO:0051208180.012
memoryGO:0007613580.012
lateral inhibitionGO:004633110.012
Fly
purine ribonucleoside monophosphate catabolic processGO:0009169570.012
negative regulation of neuron deathGO:1901215980.012
cerebral cortex developmentGO:0021987860.012
neuromuscular processGO:0050905990.012
cytosolic calcium ion homeostasisGO:0051480700.012
cell growthGO:00160491300.012
positive regulation of secretion by cellGO:19035321140.012
negative regulation of cell cycleGO:00457861230.012
negative regulation of neuron differentiationGO:00456651010.012
positive regulation of potassium ion transportGO:004326830.012
metencephalon developmentGO:0022037890.012
mitotic cell cycleGO:00002781950.012
response to acid chemicalGO:00011011110.012
negative regulation of proteolysisGO:0045861740.012
establishment of protein localization to membraneGO:0090150540.012
response to peptideGO:19016521360.012
atp catabolic processGO:0006200550.012
blood vessel morphogenesisGO:00485142850.012
urogenital system developmentGO:00016552610.012
anion transmembrane transportGO:0098656710.012
regulation of membrane repolarizationGO:006030670.012
regulation of transmembrane transportGO:00347621280.012
compound eye developmentGO:004874910.012
rho protein signal transductionGO:0007266320.012
regulation of cell morphogenesis involved in differentiationGO:00107691510.012
hindbrain developmentGO:00309021280.012
t cell activationGO:00421102890.012
habituationGO:004695930.012
cellular macromolecule catabolic processGO:00442652060.012
carbohydrate homeostasisGO:00335001280.012
reactive oxygen species biosynthetic processGO:190340980.011
regulation of translationGO:0006417710.011
spermatogenesisGO:00072832840.011
regulation of endocytosisGO:0030100690.011
Worm
response to drugGO:0042493750.011
negative regulation of neuron apoptotic processGO:0043524920.011
immune effector processGO:00022523210.011
regulation of cell projection organizationGO:00313442060.011
regulation of body fluid levelsGO:00508781620.011
covalent chromatin modificationGO:00165691630.011
dendrite developmentGO:00163581150.011
maintenance of locationGO:0051235890.011
Worm
regulation of cellular component sizeGO:00325351210.011
regulation of neurotransmitter levelsGO:0001505870.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
mitotic cell cycle processGO:19030471590.011
calcium ion transportGO:00068161590.011
regulation of peptide transportGO:0090087910.011
cell maturationGO:00484691270.011
cellular protein complex assemblyGO:00436231160.011
male gamete generationGO:00482322850.011
multicellular organismal signalingGO:0035637910.011
regulation of hormone secretionGO:0046883880.011
cellular response to organic cyclic compoundGO:0071407870.011
nuclear divisionGO:00002801580.011
protein importGO:00170381010.011
regulation of leukocyte differentiationGO:19021051590.011
regulation of synaptic plasticityGO:0048167870.011
positive regulation of cell deathGO:00109422240.011
cellular carbohydrate metabolic processGO:00442621190.011
protein localization to nucleusGO:00345041210.011
regulation of engulfment of apoptotic cellGO:190107420.011
positive regulation of cell activationGO:00508671580.011
potassium ion homeostasisGO:005507540.011
regulation of peptidyl tyrosine phosphorylationGO:0050730930.011
regulation of beta amyloid clearanceGO:190022110.011
organic hydroxy compound biosynthetic processGO:1901617770.011
lymphocyte homeostasisGO:0002260640.011
positive regulation of lymphocyte activationGO:00512511400.011
membrane fusionGO:0061025380.011
Fly
positive regulation of nervous system developmentGO:00519622210.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.010
translationGO:0006412930.010
innate immune responseGO:00450871570.010
protein lipidationGO:0006497280.010
respiratory system processGO:0003016250.010
regulation of muscle system processGO:0090257800.010
positive regulation of protein transportGO:0051222930.010
glycerolipid biosynthetic processGO:0045017500.010
negative regulation of intracellular signal transductionGO:19025321670.010
ceramide biosynthetic processGO:0046513200.010
protein localization to plasma membraneGO:0072659570.010
response to lipopolysaccharideGO:00324961280.010
regulation of protein maturationGO:1903317960.010
proteolysis involved in cellular protein catabolic processGO:00516031470.010
protein processingGO:00164851630.010
lipid localizationGO:00108761260.010
Worm
epidermis developmentGO:00085441870.010
Mouse
oocyte axis specificationGO:000730920.010
negative regulation of protein phosphorylationGO:00019331260.010
development of primary sexual characteristicsGO:00451371430.010
negative regulation of cell morphogenesis involved in differentiationGO:0010771480.010

Mcoln1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.091
central nervous system diseaseDOID:33100.091
disease of anatomical entityDOID:700.091
disease of metabolismDOID:001466700.070
inherited metabolic disorderDOID:65500.049
immune system diseaseDOID:291400.021
neurodegenerative diseaseDOID:128900.013
hematopoietic system diseaseDOID:7400.013
cardiovascular system diseaseDOID:128700.011
neuropathyDOID:87000.010
neuromuscular diseaseDOID:44000.010