IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Eftud2

elongation factor Tu GTP binding domain containing 2

(Aliases: 116kDa,Snrp116,U5-116kD)

Ensembl: ENSMUSG00000020929
Entrez: 20624
UniProtKB: A2AH85
UniProtKB: O08810
UniProtKB: Q543F1

Process Predictions
Disease Predictions

Eftud2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
dna metabolic process	GO:0006259	303	0.481
meiotic nuclear division	GO:0007126	115	0.254
regulation of cell cycle	GO:0051726	281	0.254
purine nucleoside catabolic process	GO:0006152	205	0.228
microtubule based process	GO:0007017	236	0.215
nuclear division	GO:0000280	158	0.204
microtubule cytoskeleton organization	GO:0000226	157	0.203
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.197
trna wobble uridine modification	GO:0002098	2	0.183
dna repair	GO:0006281	107	0.176
protein modification by small protein conjugation or removal	GO:0070647	207	0.150
organic cyclic compound catabolic process	GO:1901361	295	0.144
chromatin organization	GO:0006325	206	0.142
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.141
nucleoside triphosphate metabolic process	GO:0009141	230	0.136
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.132
aromatic compound catabolic process	GO:0019439	286	0.127
nucleoside metabolic process	GO:0009116	246	0.123
base excision repair	GO:0006284	9	0.122
trna wobble base modification	GO:0002097	2	0.119
transcription coupled nucleotide excision repair	GO:0006283	2	0.115
nucleoside phosphate metabolic process	GO:0006753	338	0.114
mitotic cell cycle	GO:0000278	195	0.112
ribonucleotide metabolic process	GO:0009259	291	0.106
interspecies interaction between organisms	GO:0044419	83	0.105
receptor mediated endocytosis	GO:0006898	51	0.102
meiotic cell cycle	GO:0051321	122	0.102
endocytosis	GO:0006897	168	0.100
nuclear export	GO:0051168	34	0.098
regulation of purine nucleotide catabolic process	GO:0033121	122	0.095
posttranscriptional regulation of gene expression	GO:0010608	155	0.093
purine containing compound metabolic process	GO:0072521	311	0.092
heterocycle catabolic process	GO:0046700	280	0.092
viral process	GO:0016032	41	0.088
development of primary sexual characteristics	GO:0045137	143	0.084
organelle fission	GO:0048285	170	0.082
nucleoside triphosphate catabolic process	GO:0009143	205	0.082
mrna transport	GO:0051028	13	0.082
regulation of intracellular transport	GO:0032386	159	0.080
cellular nitrogen compound catabolic process	GO:0044270	280	0.077
chemotaxis	GO:0006935	247	0.077
maintenance of location	GO:0051235	89	0.077
protein modification by small protein conjugation	GO:0032446	187	0.077
ribonucleoside metabolic process	GO:0009119	245	0.077
double strand break repair via homologous recombination	GO:0000724	21	0.076
atp catabolic process	GO:0006200	55	0.076
purine ribonucleotide catabolic process	GO:0009154	208	0.075
nucleotide excision repair	GO:0006289	13	0.075
cellular ketone metabolic process	GO:0042180	84	0.074
nucleobase containing small molecule metabolic process	GO:0055086	352	0.074
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.071
ribonucleotide catabolic process	GO:0009261	208	0.070
ribose phosphate metabolic process	GO:0019693	291	0.069
glycosyl compound metabolic process	GO:1901657	246	0.068
molting cycle	GO:0042303	90	0.068
gene silencing	GO:0016458	38	0.066
protein dna complex subunit organization	GO:0071824	28	0.064
recombinational repair	GO:0000725	21	0.064
chromatin modification	GO:0016568	187	0.064
regulation of mitotic cell cycle	GO:0007346	126	0.063
regulation of cell cycle process	GO:0010564	160	0.061
gonad development	GO:0008406	141	0.059
organophosphate catabolic process	GO:0046434	232	0.059
purine nucleotide catabolic process	GO:0006195	211	0.058
mrna metabolic process	GO:0016071	84	0.057
negative regulation of cell cycle	GO:0045786	123	0.056
purine ribonucleotide metabolic process	GO:0009150	290	0.053
trna metabolic process	GO:0006399	11	0.052
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.052
blastocyst development	GO:0001824	80	0.050
translation	GO:0006412	93	0.050
nucleoside catabolic process	GO:0009164	206	0.047
nucleotide catabolic process	GO:0009166	217	0.047
ribonucleoside catabolic process	GO:0042454	206	0.047
carbohydrate derivative catabolic process	GO:1901136	231	0.047
regulation of symbiosis encompassing mutualism through parasitism	GO:0043903	52	0.047
regulation of cytoplasmic transport	GO:1903649	112	0.045
nuclear transport	GO:0051169	139	0.045
purine containing compound catabolic process	GO:0072523	213	0.044
regulation of protein localization	GO:0032880	231	0.044
cellular amine metabolic process	GO:0044106	44	0.044
negative regulation of cellular component organization	GO:0051129	194	0.044
nucleotide metabolic process	GO:0009117	332	0.042
viral life cycle	GO:0019058	36	0.042
regulation of intracellular protein transport	GO:0033157	82	0.041
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.041
purine ribonucleoside metabolic process	GO:0046128	241	0.041
cytoplasmic translational initiation	GO:0002183	3	0.040
purine nucleotide metabolic process	GO:0006163	302	0.040
cellular amino acid metabolic process	GO:0006520	103	0.040
cellular response to dna damage stimulus	GO:0006974	207	0.040
cytoplasmic transport	GO:0016482	234	0.040
positive regulation of protein modification process	GO:0031401	299	0.040
organonitrogen compound catabolic process	GO:1901565	264	0.039
neuron projection guidance	GO:0097485	141	0.039
dna dealkylation	GO:0035510	11	0.037
dendrite development	GO:0016358	115	0.037
blastocyst hatching	GO:0001835	4	0.037
rna interference	GO:0016246	2	0.036
viral gene expression	GO:0019080	3	0.035
dna templated transcriptional preinitiation complex assembly	GO:0070897	4	0.035
regulation of histone modification	GO:0031056	56	0.034
rna splicing	GO:0008380	54	0.034
purine ribonucleoside catabolic process	GO:0046130	205	0.033
regulation of nucleotide metabolic process	GO:0006140	169	0.033
genitalia development	GO:0048806	37	0.032
dna modification	GO:0006304	50	0.032
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	68	0.032
amine metabolic process	GO:0009308	45	0.032
cellular macromolecule catabolic process	GO:0044265	206	0.032
positive regulation of intracellular protein transport	GO:0090316	42	0.032
protein modification by small protein removal	GO:0070646	21	0.031
post embryonic retina morphogenesis in camera type eye	GO:0060060	3	0.031
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.031
protein ubiquitination	GO:0016567	171	0.031
negative regulation of cellular protein metabolic process	GO:0032269	247	0.030
double strand break repair	GO:0006302	48	0.030
metal ion homeostasis	GO:0055065	189	0.030
cellular protein complex assembly	GO:0043623	116	0.029
mitotic cell cycle process	GO:1903047	159	0.029
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045899	2	0.029
nucleoside phosphate catabolic process	GO:1901292	222	0.029
positive regulation of cellular amine metabolic process	GO:0033240	5	0.028
carbohydrate derivative biosynthetic process	GO:1901137	183	0.028
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	3	0.028
purine nucleoside metabolic process	GO:0042278	241	0.028
dna recombination	GO:0006310	92	0.028
dna geometric change	GO:0032392	7	0.028
methylation	GO:0032259	134	0.028
single organism nuclear import	GO:1902593	95	0.028
positive regulation of intracellular transport	GO:0032388	70	0.027
regulation of transcription by chromatin organization	GO:0034401	0	0.027
negative regulation of cell cycle process	GO:0010948	69	0.027
negative regulation of protein metabolic process	GO:0051248	282	0.027
multi multicellular organism process	GO:0044706	109	0.026
multicellular organismal homeostasis	GO:0048871	164	0.026
regulation of cellular ketone metabolic process	GO:0010565	66	0.026
peptidyl amino acid modification	GO:0018193	336	0.026
protein localization to organelle	GO:0033365	185	0.026
nucleocytoplasmic transport	GO:0006913	139	0.026
meiotic cell cycle process	GO:1903046	77	0.026
positive regulation of dna repair	GO:0045739	3	0.026
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.026
protein complex disassembly	GO:0043241	40	0.025
rna phosphodiester bond hydrolysis endonucleolytic	GO:0090502	10	0.025
trna modification	GO:0006400	9	0.025
cellular homeostasis	GO:0019725	240	0.025
rna dependent dna replication	GO:0006278	3	0.025
dna unwinding involved in dna replication	GO:0006268	5	0.024
posttranscriptional gene silencing	GO:0016441	10	0.024
stem cell differentiation	GO:0048863	268	0.024
glycosyl compound catabolic process	GO:1901658	206	0.024
axon guidance	GO:0007411	141	0.024
organism emergence from protective structure	GO:0071684	4	0.024
spindle organization	GO:0007051	28	0.023
divalent inorganic cation homeostasis	GO:0072507	138	0.023
hatching	GO:0035188	4	0.023
embryonic organ morphogenesis	GO:0048562	276	0.023
calcium ion homeostasis	GO:0055074	127	0.022
regulation of establishment of protein localization	GO:0070201	181	0.022
axonogenesis	GO:0007409	274	0.022
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.022
histone monoubiquitination	GO:0010390	3	0.021
skin development	GO:0043588	220	0.021
negative regulation of organelle organization	GO:0010639	90	0.021
cellular response to cytokine stimulus	GO:0071345	189	0.021
mrna splicing via spliceosome	GO:0000398	43	0.020
positive regulation of transcription elongation from rna polymerase ii promoter	GO:0032968	2	0.020
gene silencing by rna	GO:0031047	19	0.020
body morphogenesis	GO:0010171	45	0.020
rhythmic process	GO:0048511	174	0.020
calcium ion transport	GO:0006816	159	0.019
chromatin silencing	GO:0006342	15	0.019
regulation of protein import into nucleus	GO:0042306	52	0.019
positive regulation of dna templated transcription elongation	GO:0032786	2	0.019
negative regulation of cell development	GO:0010721	169	0.019
regulation of nucleotide catabolic process	GO:0030811	122	0.019
chromatin disassembly	GO:0031498	1	0.019
positive regulation of histone modification	GO:0031058	28	0.019
cation homeostasis	GO:0055080	212	0.019
ribonucleoside monophosphate catabolic process	GO:0009158	57	0.019
negative regulation of gene expression epigenetic	GO:0045814	15	0.019
histone modification	GO:0016570	159	0.018
mrna export from nucleus	GO:0006406	11	0.018
viral transcription	GO:0019083	3	0.018
vitamin d receptor signaling pathway	GO:0070561	2	0.018
nucleic acid phosphodiester bond hydrolysis	GO:0090305	49	0.018
positive regulation of nfat protein import into nucleus	GO:0051533	1	0.018
organophosphate biosynthetic process	GO:0090407	122	0.018
establishment of protein localization to organelle	GO:0072594	118	0.017
ncrna processing	GO:0034470	26	0.017
transmembrane transport	GO:0055085	412	0.017
negative regulation of histone h3 k9 methylation	GO:0051573	4	0.017
rna processing	GO:0006396	105	0.017
establishment of rna localization	GO:0051236	18	0.017
cellular chemical homeostasis	GO:0055082	215	0.017
macromolecule catabolic process	GO:0009057	281	0.017
ion transmembrane transport	GO:0034220	361	0.017
regulation of multi organism process	GO:0043900	111	0.017
jak stat cascade	GO:0007259	42	0.016
regulation of hydrolase activity	GO:0051336	246	0.016
stem cell development	GO:0048864	219	0.016
rna phosphodiester bond hydrolysis	GO:0090501	19	0.016
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.016
dephosphorylation	GO:0016311	129	0.016
regulation of cellular amino acid metabolic process	GO:0006521	5	0.016
oxidation reduction process	GO:0055114	342	0.016
negative regulation of cell proliferation	GO:0008285	296	0.016
epidermis development	GO:0008544	187	0.016
regulation of meiotic cell cycle	GO:0051445	34	0.016
regulation of cellular amine metabolic process	GO:0033238	20	0.016
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna	GO:0000463	1	0.016
protein processing	GO:0016485	163	0.015
anatomical structure homeostasis	GO:0060249	145	0.015
regulation of protein transport	GO:0051223	163	0.015
regulation of neuron projection development	GO:0010975	169	0.015
macromolecular complex disassembly	GO:0032984	43	0.015
response to amino acid	GO:0043200	37	0.015
protein targeting	GO:0006605	143	0.014
trna processing	GO:0008033	11	0.014
positive regulation of hydrolase activity	GO:0051345	148	0.014
dna duplex unwinding	GO:0032508	7	0.014
positive regulation of nucleocytoplasmic transport	GO:0046824	30	0.014
positive regulation of cytoplasmic transport	GO:1903651	40	0.014
metaphase plate congression	GO:0051310	2	0.014
purine nucleoside monophosphate catabolic process	GO:0009128	58	0.014
mrna processing	GO:0006397	63	0.014
regulation of organelle organization	GO:0033043	289	0.014
regulation of viral transcription	GO:0046782	3	0.013
negative regulation of protein modification process	GO:0031400	163	0.013
regulation of ion transmembrane transporter activity	GO:0032412	54	0.013
regulation of cellular catabolic process	GO:0031329	242	0.013
positive regulation of multi organism process	GO:0043902	26	0.013
nitrogen compound transport	GO:0071705	271	0.013
dna replication	GO:0006260	52	0.013
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.013
regulation of attachment of spindle microtubules to kinetochore	GO:0051988	3	0.013
intracellular protein transport	GO:0006886	204	0.013
cell growth	GO:0016049	130	0.013
negative regulation of molecular function	GO:0044092	258	0.013
covalent chromatin modification	GO:0016569	163	0.013
divalent metal ion transport	GO:0070838	172	0.012
negative regulation of cell cycle phase transition	GO:1901988	48	0.012
regulation of cell motility	GO:2000145	236	0.012
protein import into nucleus	GO:0006606	95	0.012
positive regulation of protein localization to nucleus	GO:1900182	30	0.012
positive regulation of chromosome organization	GO:2001252	33	0.012
telomere maintenance via telomerase	GO:0007004	1	0.012
purine ribonucleoside monophosphate catabolic process	GO:0009169	57	0.012
ribonucleoprotein complex subunit organization	GO:0071826	28	0.011
dna templated transcription elongation	GO:0006354	13	0.011
gtp catabolic process	GO:0006184	143	0.011
regulation of ion transmembrane transport	GO:0034765	119	0.011
cation transport	GO:0006812	399	0.011
atp metabolic process	GO:0046034	75	0.011
cellular response to organonitrogen compound	GO:0071417	145	0.011
telomere maintenance	GO:0000723	19	0.011
nuclear import	GO:0051170	95	0.011
organelle localization	GO:0051640	179	0.011
positive regulation of protein transport	GO:0051222	93	0.011
regulation of cytoskeleton organization	GO:0051493	122	0.011
organelle assembly	GO:0070925	177	0.011
embryonic heart tube development	GO:0035050	65	0.011
macromolecule methylation	GO:0043414	120	0.011
sensory perception	GO:0007600	245	0.011
nucleobase containing compound transport	GO:0015931	27	0.011
positive regulation of gtpase activity	GO:0043547	85	0.011
positive regulation of chromatin modification	GO:1903310	28	0.011
response to acid chemical	GO:0001101	111	0.011
regulation of cell cycle checkpoint	GO:1901976	9	0.011
mesenchymal cell differentiation	GO:0048762	107	0.011
cajal body organization	GO:0030576	1	0.010
chromatin remodeling	GO:0006338	32	0.010
transcription elongation from rna polymerase ii promoter	GO:0006368	9	0.010
telencephalon development	GO:0021537	186	0.010
regulation of chromatin modification	GO:1903308	57	0.010
regulation of protein targeting	GO:1903533	61	0.010
ossification	GO:0001503	216	0.010
ncrna 3 end processing	GO:0043628	2	0.010
mesenchyme development	GO:0060485	152	0.010

Eftud2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
sensory system disease	DOID:0050155	0.211
eye disease	DOID:5614	0.211
nervous system disease	DOID:863	0.211
eye and adnexa disease	DOID:1492	0.211
retinal disease	DOID:5679	0.211
retinal degeneration	DOID:8466	0.211
disease of anatomical entity	DOID:7	0.211
neuropathy	DOID:870	0.089
retinitis pigmentosa	DOID:10584	0.034
organ system cancer	DOID:0050686	0.022
gastrointestinal system cancer	DOID:3119	0.022
disease of cellular proliferation	DOID:14566	0.022
cancer	DOID:162	0.022
large intestine cancer	DOID:5672	0.022
intestinal cancer	DOID:10155	0.022

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