Mus musculus

0 known processes

Sh3glb2

SH3-domain GRB2-like endophilin B2

(Aliases: SPAS-1,mKIAA1848)

Sh3glb2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
establishment of melanosome localizationGO:0032401110.329
vesicle localizationGO:0051648860.167
Mouse
melanosome localizationGO:0032400120.167
intracellular protein transportGO:00068862040.117
protein localization to organelleGO:00333651850.116
Mouse
nucleoside phosphate metabolic processGO:00067533380.115
regulation of neuron differentiationGO:00456642810.114
endomembrane system organizationGO:00102561470.113
regulation of secretionGO:00510462740.113
establishment of protein localization to membraneGO:0090150540.113
Mouse
macroautophagyGO:0016236210.112
negative regulation of cellular component organizationGO:00511291940.107
nucleobase containing small molecule metabolic processGO:00550863520.107
regulation of proteolysisGO:00301621640.099
synaptic transmissionGO:00072683290.089
Mouse
organophosphate catabolic processGO:00464342320.087
regulation of synaptic growth at neuromuscular junctionGO:000858240.087
regulation of cellular ketone metabolic processGO:0010565660.087
membrane organizationGO:00610242450.084
Mouse Fly
response to organonitrogen compoundGO:00102432460.078
regulation of cellular amino acid metabolic processGO:000652150.076
plasma membrane organizationGO:0007009900.076
regulation of cellular amine metabolic processGO:0033238200.074
cellular lipid metabolic processGO:00442553230.074
Mouse
protein localization to membraneGO:00726571080.073
Mouse
regulation of organelle organizationGO:00330432890.067
Mouse
cellular ketone metabolic processGO:0042180840.066
cellular response to external stimulusGO:0071496880.065
regulation of cellular catabolic processGO:00313292420.065
anatomical structure homeostasisGO:00602491450.065
regulation of cellular component sizeGO:00325351210.065
pigment granule localizationGO:0051875130.062
establishment of organelle localizationGO:00516561220.062
Mouse
regulation of vesicle mediated transportGO:00606271390.058
Mouse Fly
establishment of vesicle localizationGO:0051650810.055
Mouse
regulation of protein localizationGO:00328802310.055
Mouse
regulation of cell projection organizationGO:00313442060.055
cellular response to biotic stimulusGO:0071216920.055
negative regulation of nervous system developmentGO:00519611560.054
chemotaxisGO:00069352470.054
regulation of neuron projection developmentGO:00109751690.053
cation transportGO:00068123990.053
mapk cascadeGO:00001652810.053
purine nucleoside triphosphate catabolic processGO:00091462030.053
positive regulation of kinase activityGO:00336741550.052
cellular nitrogen compound catabolic processGO:00442702800.051
cellular amine metabolic processGO:0044106440.050
cytoplasmic transportGO:00164822340.050
cellular amino acid metabolic processGO:00065201030.050
microtubule based processGO:00070172360.050
pigmentationGO:0043473710.048
proteolysis involved in cellular protein catabolic processGO:00516031470.048
organonitrogen compound catabolic processGO:19015652640.047
skin developmentGO:00435882200.044
regulation of endocytosisGO:0030100690.044
Mouse Fly
melanosome transportGO:0032402110.044
protein localization to nucleusGO:00345041210.044
positive regulation of programmed cell deathGO:00430682180.043
Mouse
protein targetingGO:00066051430.043
nucleoside metabolic processGO:00091162460.043
nucleotide catabolic processGO:00091662170.042
skeletal system developmentGO:00015013560.042
axonogenesisGO:00074092740.042
nucleotide metabolic processGO:00091173320.041
vacuole organizationGO:0007033380.040
monocarboxylic acid metabolic processGO:00327871910.040
regulation of autophagic vacuole assemblyGO:200078540.040
regulation of hydrolase activityGO:00513362460.040
histone modificationGO:00165701590.040
purine ribonucleoside triphosphate catabolic processGO:00092071990.039
regulation of cell sizeGO:0008361720.039
organelle assemblyGO:00709251770.039
purine nucleotide metabolic processGO:00061633020.039
dendrite developmentGO:00163581150.039
protein localization to plasma membraneGO:0072659570.038
amide transportGO:00428861380.038
regulation of anatomical structure sizeGO:00900661780.038
protein maturationGO:00516041760.038
carbohydrate derivative catabolic processGO:19011362310.037
positive regulation of neuron differentiationGO:00456661410.037
actin cytoskeleton organizationGO:00300362200.037
regulation of protein kinase activityGO:00458592320.037
covalent chromatin modificationGO:00165691630.037
tissue homeostasisGO:00018941150.037
amine metabolic processGO:0009308450.037
cell adhesionGO:00071553290.036
glycoprotein biosynthetic processGO:0009101890.036
regulation of autophagyGO:0010506300.036
regulation of transferase activityGO:00513382630.036
fatty acid metabolic processGO:00066311210.035
peptidyl tyrosine modificationGO:00182121450.035
response to extracellular stimulusGO:00099911270.035
protein polyubiquitinationGO:0000209330.035
purine ribonucleotide metabolic processGO:00091502900.035
nitrogen compound transportGO:00717052710.035
regulation of kinase activityGO:00435492490.035
lateral inhibitionGO:004633110.034
sensory organ morphogenesisGO:00905962420.034
purine nucleoside metabolic processGO:00422782410.034
locomotory behaviorGO:00076261950.034
positive regulation of cell developmentGO:00107202370.034
cellular response to molecule of bacterial originGO:0071219830.034
regulation of feeding behaviorGO:006025930.034
ribonucleotide metabolic processGO:00092592910.033
response to peptideGO:19016521360.033
peptide secretionGO:00027901140.033
positive regulation of protein phosphorylationGO:00019342420.033
carbohydrate homeostasisGO:00335001280.033
apoptotic signaling pathwayGO:00971903060.033
Mouse
peptide transportGO:00158331330.033
divalent metal ion transportGO:00708381720.033
response to nutrient levelsGO:00316671090.033
ras protein signal transductionGO:0007265770.033
regulation of purine nucleotide metabolic processGO:19005421690.032
mitochondrion organizationGO:00070051340.032
Mouse
synapse assemblyGO:0007416560.032
response to radiationGO:00093141650.032
response to metal ionGO:0010038470.032
organic hydroxy compound metabolic processGO:19016152030.032
modification dependent protein catabolic processGO:00199411330.032
regulation of synaptic plasticityGO:0048167870.032
response to organic cyclic compoundGO:00140701980.032
pigment granule transportGO:0051904120.031
regulation of cell morphogenesis involved in differentiationGO:00107691510.031
establishment of pigment granule localizationGO:0051905120.031
negative regulation of synapse assemblyGO:005196430.030
virion assemblyGO:001906810.030
heterocycle catabolic processGO:00467002800.030
ribose phosphate metabolic processGO:00196932910.030
regulation of vacuole organizationGO:004408840.030
rho protein signal transductionGO:0007266320.029
cellular response to hormone stimulusGO:00328701500.029
regulation of protein maturationGO:1903317960.029
regulation of mapk cascadeGO:00434082480.029
positive regulation of cellular amino acid metabolic processGO:004576430.029
organelle localizationGO:00516401790.029
Mouse
regulation of body fluid levelsGO:00508781620.028
organic cyclic compound catabolic processGO:19013612950.028
endocytosisGO:00068971680.028
Mouse Fly
sensory perceptionGO:00076002450.028
lipid biosynthetic processGO:00086101790.028
Mouse
glycosyl compound metabolic processGO:19016572460.028
positive regulation of apoptotic processGO:00430652170.028
Mouse
positive regulation of secretionGO:00510471300.028
negative regulation of cellular amino acid metabolic processGO:004576300.028
response to epidermal growth factorGO:007084940.028
positive regulation of cell deathGO:00109422240.027
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.027
telencephalon developmentGO:00215371860.026
negative regulation of cell cycleGO:00457861230.026
phospholipid metabolic processGO:0006644870.026
Mouse
cellular response to extracellular stimulusGO:0031668810.026
glial cell differentiationGO:00100011310.026
organelle fissionGO:00482851700.026
internal protein amino acid acetylationGO:0006475420.026
nucleoside triphosphate metabolic processGO:00091412300.026
peptidyl tyrosine phosphorylationGO:00181081430.026
multicellular organism growthGO:00352641610.026
purine ribonucleoside metabolic processGO:00461282410.026
synaptic vesicle localizationGO:0097479590.026
Mouse
mitotic cell cycleGO:00002781950.025
protein modification by small protein conjugationGO:00324461870.025
purine containing compound metabolic processGO:00725213110.025
cellular response to nutrient levelsGO:0031669640.025
chromatin modificationGO:00165681870.025
regulation of cell motilityGO:20001452360.025
purine ribonucleoside catabolic processGO:00461302050.025
response to lipopolysaccharideGO:00324961280.025
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.025
nucleoside triphosphate catabolic processGO:00091432050.025
regulation of establishment of protein localizationGO:00702011810.025
Mouse
positive regulation of protein modification processGO:00314012990.025
cellular homeostasisGO:00197252400.025
cognitionGO:00508901490.025
negative regulation of molecular functionGO:00440922580.024
negative regulation of phosphorylationGO:00423261660.024
anion transportGO:00068201770.024
compound eye developmentGO:004874910.024
ion transmembrane transportGO:00342203610.024
multicellular organismal homeostasisGO:00488711640.024
germ cell developmentGO:00072811850.023
regulation of system processGO:00440572000.023
glucose transportGO:0015758560.023
purine ribonucleoside triphosphate metabolic processGO:00092052200.023
rap protein signal transductionGO:003248630.023
oocyte axis specificationGO:000730920.023
symbiosis encompassing mutualism through parasitismGO:0044403830.023
meiotic nuclear divisionGO:00071261150.023
regulation of developmental pigmentationGO:0048070140.023
regulation of nucleoside metabolic processGO:00091181300.022
ribonucleoside triphosphate catabolic processGO:00092031990.022
epidermis developmentGO:00085441870.022
small molecule catabolic processGO:0044282710.022
aromatic compound catabolic processGO:00194392860.022
response to inorganic substanceGO:0010035960.022
protein import into nucleusGO:0006606950.022
negative regulation of organelle organizationGO:0010639900.022
single organism nuclear importGO:1902593950.022
response to starvationGO:0042594650.022
lipid transportGO:0006869980.022
regulation of map kinase activityGO:00434051200.022
ubiquitin dependent protein catabolic processGO:00065111290.022
establishment of protein localization to plasma membraneGO:0090002340.022
gtp catabolic processGO:00061841430.022
positive regulation of protein kinase activityGO:00458601440.022
cellular divalent inorganic cation homeostasisGO:00725031270.022
microtubule cytoskeleton organizationGO:00002261570.022
actin filament organizationGO:00070151130.021
synapse organizationGO:00508081250.021
protein modification by small protein conjugation or removalGO:00706472070.021
negative regulation of protein phosphorylationGO:00019331260.021
purine nucleotide catabolic processGO:00061952110.021
negative regulation of cell developmentGO:00107211690.021
chromatin organizationGO:00063252060.021
developmental maturationGO:00217001930.021
positive regulation of apoptotic signaling pathwayGO:2001235950.021
Mouse
cellular response to starvationGO:0009267570.021
regulation of secretion by cellGO:19035302490.021
carbohydrate transportGO:0008643620.021
ribonucleoside triphosphate metabolic processGO:00091992200.021
negative regulation of protein metabolic processGO:00512482820.021
nucleoside phosphate biosynthetic processGO:1901293790.021
response to light stimulusGO:00094161350.021
regulation of gtp catabolic processGO:00331241130.020
wound healingGO:00420601570.020
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.020
lung developmentGO:00303241640.020
purine nucleoside catabolic processGO:00061522050.020
guanosine containing compound catabolic processGO:19010691440.020
nucleocytoplasmic transportGO:00069131390.020
posttranscriptional regulation of gene expressionGO:00106081550.020
positive regulation of hormone secretionGO:0046887380.020
peptidyl amino acid modificationGO:00181933360.020
regulation of sequence specific dna binding transcription factor activityGO:00510901060.020
negative regulation of phosphate metabolic processGO:00459361840.020
regulation of metal ion transportGO:00109591060.020
protein targeting to membraneGO:0006612200.020
negative regulation of cellular amine metabolic processGO:003323910.020
regulation of cellular component biogenesisGO:00440871810.019
regulation of ion transportGO:00432692150.019
positive regulation of nervous system developmentGO:00519622210.019
protein processingGO:00164851630.019
response to molecule of bacterial originGO:00022371430.019
regulation of homeostatic processGO:00328441820.019
response to growth factorGO:00708481980.019
ribonucleoside metabolic processGO:00091192450.019
retrograde transport endosome to golgiGO:004214720.019
regulation of actin filament based processGO:0032970990.019
urogenital system developmentGO:00016552610.019
camera type eye developmentGO:00430102660.018
neuron projection extensionGO:1990138640.018
positive regulation of cellular amine metabolic processGO:003324050.018
nuclear transportGO:00511691390.018
cellular response to lipidGO:00713961450.018
developmental growth involved in morphogenesisGO:00605601380.018
protein secretionGO:00093061110.018
glucose homeostasisGO:00425931280.018
cation homeostasisGO:00550802120.018
cellular response to organonitrogen compoundGO:00714171450.018
regulation of cell cycleGO:00517262810.018
purine nucleoside triphosphate metabolic processGO:00091442260.018
cell substrate adhesionGO:00315891300.018
cell type specific apoptotic processGO:00972852680.018
positive regulation of dendrite developmentGO:1900006210.018
calcium ion homeostasisGO:00550741270.018
adult locomotory behaviorGO:0008344910.018
organic hydroxy compound transportGO:0015850930.018
activation of adenylate cyclase activityGO:000719040.018
cellular carbohydrate metabolic processGO:00442621190.018
glycerolipid metabolic processGO:00464861220.018
Mouse
extrinsic apoptotic signaling pathwayGO:00971911260.018
cholesterol storageGO:001087840.018
fatty acid biosynthetic processGO:0006633410.017
regulation of intracellular transportGO:00323861590.017
Mouse
hormone secretionGO:00468791280.017
developmental cell growthGO:0048588840.017
learning or memoryGO:00076111480.017
respiratory tube developmentGO:00303231670.017
glycosyl compound catabolic processGO:19016582060.017
positive regulation of neuron projection developmentGO:0010976790.017
ribonucleotide catabolic processGO:00092612080.017
purine containing compound catabolic processGO:00725232130.017
divalent inorganic cation homeostasisGO:00725071380.017
gtp metabolic processGO:00460391440.017
microtubule based transportGO:0010970500.017
regulation of cell migrationGO:00303342190.017
guanosine containing compound metabolic processGO:19010681440.017
oxidation reduction processGO:00551143420.017
protein importGO:00170381010.017
cholesterol transportGO:0030301380.017
regulation of sterol transportGO:0032371170.017
autophagyGO:0006914450.017
alcohol metabolic processGO:00060661160.016
organic acid biosynthetic processGO:0016053860.016
negative regulation of mapk cascadeGO:0043409650.016
positive regulation of secretion by cellGO:19035321140.016
regulation of ras gtpase activityGO:0032318880.016
negative regulation of neuron deathGO:1901215980.016
cellular response to dna damage stimulusGO:00069742070.016
adult behaviorGO:00305341350.016
cellular response to lipopolysaccharideGO:0071222770.016
regulation of tor signalingGO:0032006170.016
hexose transportGO:0008645560.016
regulation of myeloid cell differentiationGO:0045637960.016
regulation of actin cytoskeleton organizationGO:0032956840.016
regulation of peptide hormone secretionGO:0090276750.016
regulation of extent of cell growthGO:0061387520.016
cellular response to cytokine stimulusGO:00713451890.016
nuclear divisionGO:00002801580.015
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.015
regulation of protein transportGO:00512231630.015
ribonucleoside monophosphate metabolic processGO:0009161800.015
transmembrane transportGO:00550854120.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.015
nuclear importGO:0051170950.015
sterol transportGO:0015918380.015
single organism cell adhesionGO:00986021560.015
respiratory system developmentGO:00605411900.015
organophosphate biosynthetic processGO:00904071220.015
Mouse
negative regulation of protein processingGO:0010955790.015
cell maturationGO:00484691270.015
axon guidanceGO:00074111410.015
lipid modificationGO:0030258650.015
gliogenesisGO:00420631410.015
negative regulation of dna replicationGO:000815640.015
regulation of peptidyl tyrosine phosphorylationGO:0050730930.015
cell growthGO:00160491300.015
peptidyl lysine modificationGO:0018205770.015
regulation of response to woundingGO:19030341890.015
cellular pigmentationGO:0033059200.015
cellular response to cadmium ionGO:007127630.015
male gamete generationGO:00482322850.014
positive regulation of peptide hormone secretionGO:0090277310.014
cellular metal ion homeostasisGO:00068751510.014
intrinsic apoptotic signaling pathwayGO:00971931320.014
negative regulation of protein modification processGO:00314001630.014
positive regulation of cell cycleGO:0045787920.014
regulation of response to drugGO:200102320.014
muscle cell differentiationGO:00426922610.014
protein ubiquitinationGO:00165671710.014
glycoprotein metabolic processGO:00091001160.014
regulation of peptide secretionGO:0002791770.014
exocytosisGO:00068871210.014
cytoskeleton dependent intracellular transportGO:0030705500.014
regulation of lipid metabolic processGO:00192161180.014
regulation of cell adhesionGO:00301551540.014
negative regulation of homeostatic processGO:0032845710.014
cellular response to abiotic stimulusGO:0071214560.014
positive regulation of cellular component biogenesisGO:0044089940.014
small gtpase mediated signal transductionGO:0007264970.014
cation transmembrane transportGO:00986552660.014
regulation of endopeptidase activityGO:0052548890.014
glycerophospholipid metabolic processGO:0006650710.014
Mouse
cell fate commitmentGO:00451652100.014
insulin secretionGO:0030073890.014
response to alkaloidGO:0043279340.014
homeostasis of number of cellsGO:00488722100.014
nucleoside catabolic processGO:00091642060.013
regulation of hormone levelsGO:00108172110.013
lipid localizationGO:00108761260.013
positive regulation of cell cycle processGO:0090068610.013
positive regulation of gtpase activityGO:0043547850.013
regulation of bindingGO:00510981110.013
regulation of purine nucleotide catabolic processGO:00331211220.013
macromolecule catabolic processGO:00090572810.013
cellular response to peptideGO:1901653920.013
angiogenesisGO:00015252010.013
purine ribonucleotide catabolic processGO:00091542080.013
negative regulation of phosphorus metabolic processGO:00105631840.013
calcium ion transportGO:00068161590.013
forebrain developmentGO:00309003020.013
regulation of intracellular protein transportGO:0033157820.013
central nervous system neuron developmentGO:0021954670.013
feeding behaviorGO:0007631620.013
positive regulation of cysteine type endopeptidase activityGO:2001056390.013
positive regulation of hydrolase activityGO:00513451480.013
leukocyte migrationGO:00509001240.013
embryonic skeletal system developmentGO:00487061200.013
photoreceptor cell differentiationGO:0046530520.013
monosaccharide transportGO:0015749580.013
establishment of protein localization to organelleGO:00725941180.012
Mouse
cell junction maintenanceGO:003433140.012
regulation of membrane potentialGO:00423911920.012
regulation of protein catabolic processGO:00421761080.012
positive regulation of nucleotide catabolic processGO:0030813880.012
regulation of nucleotide catabolic processGO:00308111220.012
steroid metabolic processGO:00082021190.012
carbohydrate derivative biosynthetic processGO:19011371830.012
learningGO:0007612980.012
positive regulation of ras gtpase activityGO:0032320650.012
organophosphate ester transportGO:0015748280.012
generation of precursor metabolites and energyGO:00060911030.012
sequestering of metal ionGO:0051238190.012
gastrulationGO:00073691160.012
cellular response to inorganic substanceGO:0071241370.012
connective tissue developmentGO:00614481790.012
myeloid cell differentiationGO:00300992330.012
positive regulation of transferase activityGO:00513471670.012
development of primary sexual characteristicsGO:00451371430.012
inorganic ion transmembrane transportGO:00986602340.012
positive regulation of intracellular protein transportGO:0090316420.012
regulation of transpositionGO:001052820.012
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.012
cytokine productionGO:00018163190.012
organonitrogen compound biosynthetic processGO:19015661920.012
glial cell developmentGO:0021782540.012
rhythmic processGO:00485111740.012
divalent inorganic cation transportGO:00725111780.012
regulation of defense responseGO:00313472330.012
interspecies interaction between organismsGO:0044419830.012
protein autophosphorylationGO:0046777610.012
circulatory system processGO:00030131970.012
regulation of cytoskeleton organizationGO:00514931220.011
negative regulation of kinase activityGO:0033673810.011
cellular response to growth factor stimulusGO:00713631970.011
sensory system developmentGO:004888030.011
digestive system developmentGO:00551232000.011
dna metabolic processGO:00062593030.011
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.011
regulation of protein serine threonine kinase activityGO:00719001570.011
response to insulinGO:00328681000.011
negative regulation of cell proliferationGO:00082852960.011
heart processGO:0003015940.011
axon cargo transportGO:0008088330.011
multi multicellular organism processGO:00447061090.011
regulation of apoptotic signaling pathwayGO:20012331970.011
Mouse
positive regulation of protein transportGO:0051222930.011
protein oligomerizationGO:0051259670.011
ribonucleoside catabolic processGO:00424542060.011
spermatogenesisGO:00072832840.011
positive regulation of macroautophagyGO:001623930.011
t cell receptor signaling pathwayGO:0050852460.011
peptidyl threonine modificationGO:0018210310.011
positive regulation of mapk cascadeGO:00434101700.011
innate immune responseGO:00450871570.011
blood circulationGO:00080151950.011
jnk cascadeGO:0007254720.011
regulation of nucleotide metabolic processGO:00061401690.011
synaptic vesicle transportGO:0048489570.011
Mouse
negative regulation of endothelial cell migrationGO:001059640.011
neutral lipid metabolic processGO:0006638570.011
digestive tract morphogenesisGO:00485461470.011
macromolecule methylationGO:00434141200.011
negative regulation of cellular catabolic processGO:0031330470.011
insulin receptor signaling pathwayGO:0008286490.011
microtubule based movementGO:0007018840.011
metal ion homeostasisGO:00550651890.010
positive regulation of peptide secretionGO:0002793330.010
retina development in camera type eyeGO:00600411190.010
pallium developmentGO:00215431200.010
positive regulation of ion transportGO:0043270650.010
glucose importGO:0046323320.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
apoptotic mitochondrial changesGO:0008637480.010
Mouse
negative regulation of proteolysisGO:0045861740.010
protein transport into membrane raftGO:003259640.010
golgi vesicle transportGO:0048193300.010
acylglycerol metabolic processGO:0006639550.010
regulation of erk1 and erk2 cascadeGO:0070372710.010
phospholipid transfer to membraneGO:000664920.010
regulation of anterior head developmentGO:200074220.010
inorganic cation transmembrane transportGO:00986622070.010
ionotropic glutamate receptor signaling pathwayGO:0035235290.010

Sh3glb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:128700.049
disease of anatomical entityDOID:700.049
nervous system diseaseDOID:86300.036
immune system diseaseDOID:291400.013
hematopoietic system diseaseDOID:7400.013
heart diseaseDOID:11400.010
central nervous system diseaseDOID:33100.010