| proteasomal ubiquitin independent protein catabolic process | GO:0010499 | 1 | 0.845 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.772 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.750 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.625 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.609 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.563 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.465 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.451 | |
| protein catabolic process | GO:0030163 | 221 | 0.428 | |
| proteasome assembly | GO:0043248 | 1 | 0.403 | Human |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.388 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.366 | |
| amine metabolic process | GO:0009308 | 45 | 0.284 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.259 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.166 | |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.155 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.146 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.145 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.144 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.137 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.126 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.112 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.101 | |
| positive regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045899 | 2 | 0.097 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.083 | |
| regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045898 | 2 | 0.081 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.077 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.077 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.070 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.063 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.063 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.061 | |
| t cell proliferation | GO:0042098 | 120 | 0.061 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.053 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.051 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.050 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.048 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.048 | |
| cellular homeostasis | GO:0019725 | 240 | 0.048 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.047 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.047 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.047 | |
| mapk cascade | GO:0000165 | 281 | 0.047 | |
| sphingolipid metabolic process | GO:0006665 | 45 | 0.047 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.047 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.046 | |
| membrane organization | GO:0061024 | 245 | 0.046 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.046 | |
| regulation of endopeptidase activity | GO:0052548 | 89 | 0.043 | |
| apoptotic mitochondrial changes | GO:0008637 | 48 | 0.043 | |
| protein import | GO:0017038 | 101 | 0.042 | |
| blastocyst development | GO:0001824 | 80 | 0.042 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.041 | |
| rna splicing | GO:0008380 | 54 | 0.041 | |
| glucose homeostasis | GO:0042593 | 128 | 0.040 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.039 | |
| rna splicing via transesterification reactions with bulged adenosine as nucleophile | GO:0000377 | 43 | 0.039 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.039 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.038 | |
| protein import into nucleus | GO:0006606 | 95 | 0.037 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.037 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.037 | |
| dna templated transcriptional preinitiation complex assembly | GO:0070897 | 4 | 0.036 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.034 | |
| organelle fission | GO:0048285 | 170 | 0.033 | |
| synaptic transmission | GO:0007268 | 329 | 0.033 | |
| extracellular structure organization | GO:0043062 | 148 | 0.033 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.033 | |
| recombinational repair | GO:0000725 | 21 | 0.033 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.032 | |
| protein ubiquitination | GO:0016567 | 171 | 0.031 | |
| gonad development | GO:0008406 | 141 | 0.031 | |
| regulation of engulfment of apoptotic cell | GO:1901074 | 2 | 0.030 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.030 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.030 | |
| t cell activation | GO:0042110 | 289 | 0.029 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.029 | |
| extracellular matrix organization | GO:0030198 | 147 | 0.029 | |
| regulation of phospholipid biosynthetic process | GO:0071071 | 3 | 0.028 | |
| dna metabolic process | GO:0006259 | 303 | 0.028 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.028 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.027 | |
| neural tube formation | GO:0001841 | 108 | 0.027 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.027 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.027 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.027 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.026 | |
| intracellular protein transport | GO:0006886 | 204 | 0.026 | |
| forebrain development | GO:0030900 | 302 | 0.026 | |
| cellular response to glucose stimulus | GO:0071333 | 45 | 0.025 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.025 | |
| fertilization | GO:0009566 | 127 | 0.025 | |
| rna polymerase ii transcriptional preinitiation complex assembly | GO:0051123 | 3 | 0.025 | |
| glycerophospholipid metabolic process | GO:0006650 | 71 | 0.025 | |
| negative regulation of leukocyte differentiation | GO:1902106 | 51 | 0.025 | |
| regulation of protein localization to nucleus | GO:1900180 | 60 | 0.024 | |
| protein localization to organelle | GO:0033365 | 185 | 0.024 | |
| positive regulation of proteolysis involved in cellular protein catabolic process | GO:1903052 | 31 | 0.024 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 80 | 0.024 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.023 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.023 | |
| purine deoxyribonucleoside triphosphate metabolic process | GO:0009215 | 7 | 0.023 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.023 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.023 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.023 | |
| nuclear import | GO:0051170 | 95 | 0.023 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.023 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.023 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.022 | |
| regulation of protein targeting | GO:1903533 | 61 | 0.022 | |
| microtubule based process | GO:0007017 | 236 | 0.022 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.022 | |
| regulation of release of cytochrome c from mitochondria | GO:0090199 | 11 | 0.022 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.022 | |
| regulation of peptidase activity | GO:0052547 | 96 | 0.021 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 65 | 0.021 | |
| cation transport | GO:0006812 | 399 | 0.021 | |
| response to drug | GO:0042493 | 75 | 0.021 | |
| positive regulation of protein catabolic process | GO:0045732 | 60 | 0.021 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.021 | |
| positive regulation of cellular protein catabolic process | GO:1903364 | 34 | 0.021 | |
| regulation of protein transport | GO:0051223 | 163 | 0.020 | |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 106 | 0.020 | |
| positive regulation of protein complex assembly | GO:0031334 | 45 | 0.020 | |
| protein polymerization | GO:0051258 | 57 | 0.020 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.020 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.020 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.020 | |
| regulation of defense response | GO:0031347 | 233 | 0.020 | |
| signal transduction by p53 class mediator | GO:0072331 | 51 | 0.020 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.019 | |
| protein localization to membrane | GO:0072657 | 108 | 0.019 | |
| cation homeostasis | GO:0055080 | 212 | 0.019 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.019 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.019 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 46 | 0.019 | |
| protein neddylation | GO:0045116 | 1 | 0.019 | |
| organelle assembly | GO:0070925 | 177 | 0.019 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.019 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.019 | |
| peptidyl serine phosphorylation | GO:0018105 | 74 | 0.019 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.019 | |
| glycerolipid metabolic process | GO:0046486 | 122 | 0.019 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.018 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.018 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.018 | |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.018 | |
| regulation of protein localization | GO:0032880 | 231 | 0.018 | |
| response to acid chemical | GO:0001101 | 111 | 0.018 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.018 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 57 | 0.018 | |
| protein modification by small protein removal | GO:0070646 | 21 | 0.018 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.017 | |
| microtubule cytoskeleton organization involved in mitosis | GO:1902850 | 4 | 0.017 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.017 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.017 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 56 | 0.017 | |
| protein targeting | GO:0006605 | 143 | 0.017 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.017 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.017 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 0.017 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.017 | |
| positive regulation of peptidase activity | GO:0010952 | 49 | 0.017 | |
| maintenance of location | GO:0051235 | 89 | 0.017 | |
| neural tube development | GO:0021915 | 160 | 0.017 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.017 | |
| negative regulation of release of cytochrome c from mitochondria | GO:0090201 | 6 | 0.017 | |
| peptide transport | GO:0015833 | 133 | 0.017 | |
| exocytosis | GO:0006887 | 121 | 0.016 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 57 | 0.016 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.016 | |
| calcium ion transport | GO:0006816 | 159 | 0.016 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.016 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.016 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 40 | 0.016 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.016 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.016 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.016 | |
| epithelial tube formation | GO:0072175 | 130 | 0.016 | |
| telencephalon development | GO:0021537 | 186 | 0.016 | |
| gland development | GO:0048732 | 330 | 0.016 | |
| regulation of secretion | GO:0051046 | 274 | 0.016 | |
| cell division | GO:0051301 | 120 | 0.016 | |
| cellular response to hexose stimulus | GO:0071331 | 47 | 0.016 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.015 | |
| adult behavior | GO:0030534 | 135 | 0.015 | |
| regulation of myeloid cell differentiation | GO:0045637 | 96 | 0.015 | |
| dna recombination | GO:0006310 | 92 | 0.015 | |
| transcription initiation from rna polymerase ii promoter | GO:0006367 | 8 | 0.015 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 73 | 0.015 | |
| negative regulation of cytoplasmic transport | GO:1903650 | 29 | 0.015 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 127 | 0.015 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.015 | |
| embryonic epithelial tube formation | GO:0001838 | 130 | 0.015 | |
| spermatogenesis | GO:0007283 | 284 | 0.015 | |
| nuclear transport | GO:0051169 | 139 | 0.015 | |
| regulation of cell migration | GO:0030334 | 219 | 0.015 | |
| single fertilization | GO:0007338 | 82 | 0.015 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.015 | |
| negative regulation of intracellular transport | GO:0032387 | 38 | 0.014 | |
| organic hydroxy compound biosynthetic process | GO:1901617 | 77 | 0.014 | |
| single organism nuclear import | GO:1902593 | 95 | 0.014 | |
| regulation of cell activation | GO:0050865 | 289 | 0.014 | |
| cellular glucose homeostasis | GO:0001678 | 52 | 0.014 | |
| protein acylation | GO:0043543 | 64 | 0.014 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.014 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.014 | |
| regulation of inflammatory response | GO:0050727 | 147 | 0.014 | |
| double strand break repair via homologous recombination | GO:0000724 | 21 | 0.014 | |
| positive regulation of peptidyl serine phosphorylation | GO:0033138 | 25 | 0.014 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.014 | Human |
| amide transport | GO:0042886 | 138 | 0.013 | |
| protein processing | GO:0016485 | 163 | 0.013 | |
| positive regulation of transmembrane transport | GO:0034764 | 29 | 0.013 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.013 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.013 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.013 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.013 | |
| positive regulation of transcription initiation from rna polymerase ii promoter | GO:0060261 | 5 | 0.013 | |
| positive regulation of neuron differentiation | GO:0045666 | 141 | 0.013 | |
| positive regulation of cell cycle | GO:0045787 | 92 | 0.013 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.013 | |
| positive regulation of growth | GO:0045927 | 104 | 0.013 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.013 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.013 | |
| ribonucleotide biosynthetic process | GO:0009260 | 59 | 0.012 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.012 | |
| cytokinetic process | GO:0032506 | 2 | 0.012 | |
| protein maturation | GO:0051604 | 176 | 0.012 | |
| tube formation | GO:0035148 | 140 | 0.012 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.012 | |
| regulation of cell motility | GO:2000145 | 236 | 0.012 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.012 | |
| neuron death | GO:0070997 | 154 | 0.012 | |
| regulation of actin cytoskeleton organization | GO:0032956 | 84 | 0.012 | |
| cellular response to acid chemical | GO:0071229 | 68 | 0.012 | |
| regulation of phosphatidylcholine biosynthetic process | GO:2001245 | 2 | 0.012 | |
| cellular response to carbohydrate stimulus | GO:0071322 | 50 | 0.012 | |
| peptidyl serine modification | GO:0018209 | 83 | 0.012 | |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.012 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.012 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 79 | 0.012 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.012 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.012 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.012 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.011 | |
| transmembrane transport | GO:0055085 | 412 | 0.011 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.011 | |
| regulation of lipid metabolic process | GO:0019216 | 118 | 0.011 | |
| phenol containing compound metabolic process | GO:0018958 | 60 | 0.011 | |
| regulation of ion transport | GO:0043269 | 215 | 0.011 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.011 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 62 | 0.011 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.011 | |
| pyridine containing compound catabolic process | GO:0072526 | 4 | 0.011 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.011 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.011 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.011 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.011 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.011 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 58 | 0.011 | |
| positive regulation of endopeptidase activity | GO:0010950 | 43 | 0.011 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.011 | |
| age dependent response to oxidative stress | GO:0001306 | 3 | 0.011 | |
| atp catabolic process | GO:0006200 | 55 | 0.010 | |
| positive regulation of secretion | GO:0051047 | 130 | 0.010 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.010 | |
| regulation of endocytosis | GO:0030100 | 69 | 0.010 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.010 | |
