IMP: Integrative Multi-species Prediction

Mus musculus

83 known processes

Ptcd2

pentatricopeptide repeat domain 2

(Aliases: 1190005P08Rik)

Entrez: 68927
Ensembl: ENSMUSG00000021650
UniProtKB: Q8R3K3

Process Predictions
Disease Predictions

Ptcd2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
iron sulfur cluster assembly	GO:0016226	3	0.383
mitochondrion organization	GO:0007005	134	0.102
regulation of cellular amino acid metabolic process	GO:0006521	5	0.080
dephosphorylation	GO:0016311	129	0.060
cellular amino acid metabolic process	GO:0006520	103	0.059
cellular amine metabolic process	GO:0044106	44	0.045
amine metabolic process	GO:0009308	45	0.045
regulation of cellular amine metabolic process	GO:0033238	20	0.045
regulation of membrane potential	GO:0042391	192	0.041
regulation of cellular ketone metabolic process	GO:0010565	66	0.040
negative regulation of cellular component organization	GO:0051129	194	0.037
metallo sulfur cluster assembly	GO:0031163	3	0.036
regulation of feeding behavior	GO:0060259	3	0.035
regulation of organelle organization	GO:0033043	289	0.033
protein localization to membrane	GO:0072657	108	0.031
defecation	GO:0030421	1	0.029
regulation of lymphocyte activation	GO:0051249	240	0.029
cellular ketone metabolic process	GO:0042180	84	0.028
cytokine production	GO:0001816	319	0.028
response to oxidative stress	GO:0006979	123	0.028
peptidyl amino acid modification	GO:0018193	336	0.027
t cell activation	GO:0042110	289	0.027
positive regulation of cellular amine metabolic process	GO:0033240	5	0.026
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.026
membrane organization	GO:0061024	245	0.025
purine containing compound metabolic process	GO:0072521	311	0.024
trna wobble uridine modification	GO:0002098	2	0.023
regulation of cell activation	GO:0050865	289	0.023
purine ribonucleotide metabolic process	GO:0009150	290	0.023
negative regulation of intracellular signal transduction	GO:1902532	167	0.023
small gtpase mediated signal transduction	GO:0007264	97	0.023
nucleoside phosphate metabolic process	GO:0006753	338	0.022
positive regulation of cell activation	GO:0050867	158	0.022
intracellular protein transport	GO:0006886	204	0.022
ribose phosphate metabolic process	GO:0019693	291	0.022
dna metabolic process	GO:0006259	303	0.021
negative regulation of phosphorylation	GO:0042326	166	0.020
negative regulation of phosphate metabolic process	GO:0045936	184	0.020
mitochondrial translation	GO:0032543	4	0.020
regulation of t cell activation	GO:0050863	170	0.020
spermatogenesis	GO:0007283	284	0.019
intrinsic apoptotic signaling pathway	GO:0097193	132	0.019
positive regulation of protein modification process	GO:0031401	299	0.019
nucleotide metabolic process	GO:0009117	332	0.019
regulation of protein localization	GO:0032880	231	0.018
establishment of protein localization to organelle	GO:0072594	118	0.018
negative regulation of cellular amine metabolic process	GO:0033239	1	0.018
response to organic cyclic compound	GO:0014070	198	0.018
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.018
lymphocyte differentiation	GO:0030098	242	0.018
purine nucleotide metabolic process	GO:0006163	302	0.017
mitochondrial dna replication	GO:0006264	7	0.017
positive regulation of t cell activation	GO:0050870	101	0.017
transmembrane transport	GO:0055085	412	0.017
neuronal action potential	GO:0019228	54	0.017
nucleoside metabolic process	GO:0009116	246	0.017
regulation of protein transport	GO:0051223	163	0.016
germ cell development	GO:0007281	185	0.016
multicellular organismal signaling	GO:0035637	91	0.016
immune effector process	GO:0002252	321	0.016
regulation of establishment of protein localization	GO:0070201	181	0.016
purine ribonucleoside metabolic process	GO:0046128	241	0.016
positive regulation of lymphocyte activation	GO:0051251	140	0.016
leukocyte differentiation	GO:0002521	342	0.016
translation	GO:0006412	93	0.015
regulation of leukocyte proliferation	GO:0070663	121	0.015
regulation of ion transport	GO:0043269	215	0.015
leukocyte apoptotic process	GO:0071887	71	0.015
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.015
negative regulation of phosphorus metabolic process	GO:0010563	184	0.015
action potential	GO:0001508	78	0.015
regulation of secretion by cell	GO:1903530	249	0.014
generation of precursor metabolites and energy	GO:0006091	103	0.014
ras protein signal transduction	GO:0007265	77	0.014
regulation of t cell proliferation	GO:0042129	92	0.014
cellular protein complex assembly	GO:0043623	116	0.014
myelination	GO:0042552	74	0.014
nucleobase containing small molecule metabolic process	GO:0055086	352	0.014
t cell proliferation	GO:0042098	120	0.014
homeostasis of number of cells	GO:0048872	210	0.014
negative regulation of wnt signaling pathway	GO:0030178	73	0.013
transmission of nerve impulse	GO:0019226	76	0.013
protein localization to organelle	GO:0033365	185	0.013
response to decreased oxygen levels	GO:0036293	59	0.013
ribonucleoside metabolic process	GO:0009119	245	0.013
cellular nitrogen compound catabolic process	GO:0044270	280	0.013
trna wobble base modification	GO:0002097	2	0.013
oxidation reduction process	GO:0055114	342	0.013
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.013
synapse organization	GO:0050808	125	0.013
cellular homeostasis	GO:0019725	240	0.013
regulation of cytokine production	GO:0001817	266	0.013
response to oxygen levels	GO:0070482	62	0.013
regulation of cytoplasmic transport	GO:1903649	112	0.013
regulation of secretion	GO:0051046	274	0.013
nucleoside triphosphate metabolic process	GO:0009141	230	0.013
leukocyte homeostasis	GO:0001776	79	0.013
lymphocyte apoptotic process	GO:0070227	54	0.012
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.012
regulation of generation of precursor metabolites and energy	GO:0043467	38	0.012
positive regulation of protein phosphorylation	GO:0001934	242	0.012
negative regulation of organelle organization	GO:0010639	90	0.012
cellular response to oxidative stress	GO:0034599	76	0.012
canonical wnt signaling pathway	GO:0060070	130	0.012
cell adhesion	GO:0007155	329	0.012
inorganic cation transmembrane transport	GO:0098662	207	0.012
nitrogen compound transport	GO:0071705	271	0.012
respiratory system development	GO:0060541	190	0.012
lymphocyte homeostasis	GO:0002260	64	0.011
skeletal system development	GO:0001501	356	0.011
cation transmembrane transport	GO:0098655	266	0.011
peptide transport	GO:0015833	133	0.011
male gamete generation	GO:0048232	285	0.011
t cell homeostasis	GO:0043029	35	0.011
leukocyte proliferation	GO:0070661	172	0.011
regulation of purine nucleotide metabolic process	GO:1900542	169	0.011
cofactor metabolic process	GO:0051186	80	0.011
chromatin organization	GO:0006325	206	0.011
regulation of mapk cascade	GO:0043408	248	0.011
cell type specific apoptotic process	GO:0097285	268	0.011
maintenance of location	GO:0051235	89	0.011
t cell differentiation	GO:0030217	174	0.011
myeloid cell differentiation	GO:0030099	233	0.010
negative regulation of molecular function	GO:0044092	258	0.010
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway	GO:1902176	4	0.010
regulation of transferase activity	GO:0051338	263	0.010
ribonucleotide metabolic process	GO:0009259	291	0.010
regulation of oxidative phosphorylation	GO:0002082	6	0.010
positive regulation of protein kinase activity	GO:0045860	144	0.010
gtp catabolic process	GO:0006184	143	0.010
regulation of homeostatic process	GO:0032844	182	0.010
sensory perception	GO:0007600	245	0.010

Ptcd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
cancer	DOID:162	0.020
disease of cellular proliferation	DOID:14566	0.020
organ system cancer	DOID:0050686	0.020
nervous system disease	DOID:863	0.012
sensory system disease	DOID:0050155	0.012
eye disease	DOID:5614	0.012
disease of anatomical entity	DOID:7	0.012
eye and adnexa disease	DOID:1492	0.012

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