Mus musculus

186 known processes

Plcg2

phospholipase C, gamma 2

(Aliases: PLCgamma2,MGC38590,Plcg-2)

Plcg2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of protein metabolic processGO:00512482820.960
regulation of toll like receptor signaling pathwayGO:0034121200.880
negative regulation of phosphorus metabolic processGO:00105631840.830
innate immune response activating signal transductionGO:0002758500.808
regulation of leukocyte differentiationGO:19021051590.804
negative regulation of kinase activityGO:0033673810.793
establishment of spindle localizationGO:0051293190.782
regulation of lymphocyte differentiationGO:00456191070.772
establishment of mitotic spindle localizationGO:0040001120.750
b cell activationGO:00421131610.744
cellular amine metabolic processGO:0044106440.739
establishment or maintenance of cell polarityGO:0007163860.723
toll like receptor signaling pathwayGO:0002224380.718
spindle localizationGO:0051653220.701
regulation of cellular amine metabolic processGO:0033238200.694
negative regulation of toll like receptor signaling pathwayGO:0034122140.689
negative regulation of protein serine threonine kinase activityGO:0071901490.671
microtubule cytoskeleton organizationGO:00002261570.661
positive regulation of b cell receptor signaling pathwayGO:005086140.657
negative regulation of cellular protein metabolic processGO:00322692470.626
homotypic cell cell adhesionGO:0034109280.622
b cell receptor signaling pathwayGO:0050853200.610
negative regulation of map kinase activityGO:0043407340.600
regulation of toll like receptor 2 signaling pathwayGO:003413530.590
establishment of spindle orientationGO:0051294150.586
regulation of myeloid leukocyte differentiationGO:0002761580.585
positive regulation of podosome assemblyGO:007180330.580
pattern recognition receptor signaling pathwayGO:0002221470.575
regulation of cellular amino acid metabolic processGO:000652150.567
leukocyte differentiationGO:00025213420.565
adaptive immune responseGO:00022501550.564
negative regulation of molecular functionGO:00440922580.562
immune response inhibiting cell surface receptor signaling pathwayGO:000276730.559
regulation of actin cytoskeleton organizationGO:0032956840.548
b cell proliferationGO:0042100530.536
Mouse
regulation of protein kinase activityGO:00458592320.526
regulation of toll like receptor 4 signaling pathwayGO:003414340.525
histamine production involved in inflammatory responseGO:000234910.520
negative regulation of cellular amino acid metabolic processGO:004576300.516
regulation of cellular ketone metabolic processGO:0010565660.482
regulation of synaptic growth at neuromuscular junctionGO:000858240.473
establishment of organelle localizationGO:00516561220.469
negative regulation of protein modification processGO:00314001630.459
negative regulation of protein phosphorylationGO:00019331260.448
erythrocyte differentiationGO:0030218880.429
negative regulation of transferase activityGO:0051348850.404
regulation of dendritic cell apoptotic processGO:200066830.401
regulation of hydrolase activityGO:00513362460.398
olfactory learningGO:000835520.385
endodermal cell fate specificationGO:000171440.379
single organism cell adhesionGO:00986021560.379
regulation of t cell activationGO:00508631700.375
amine metabolic processGO:0009308450.375
divalent metal ion transportGO:00708381720.372
positive regulation of t cell differentiationGO:0045582520.365
immune response activating signal transductionGO:00027571160.364
myeloid cell differentiationGO:00300992330.362
immune response inhibiting signal transductionGO:000276540.362
myeloid leukocyte differentiationGO:00025731190.356
regulation of kinase activityGO:00435492490.351
metal ion homeostasisGO:00550651890.346
regulation of neuron projection developmentGO:00109751690.345
regulation of cell activationGO:00508652890.345
regulation of actin filament lengthGO:0030832450.343
negative regulation of synapse assemblyGO:005196430.339
positive regulation of cellular amino acid metabolic processGO:004576430.338
regulation of podosome assemblyGO:007180130.336
regulation of neutrophil differentiationGO:004565820.335
regulation of phospholipase c activityGO:190027430.330
glycerolipid metabolic processGO:00464861220.328
Human Mouse
regulation of calcium ion transportGO:0051924690.326
negative regulation of toll like receptor 2 signaling pathwayGO:003413630.321
axonogenesisGO:00074092740.315
microtubule based processGO:00070172360.315
detection of mechanical stimulus involved in sensory perception of painGO:005096640.308
regulation of erythrocyte differentiationGO:0045646230.307
organelle localizationGO:00516401790.306
regulation of actin polymerization or depolymerizationGO:0008064450.300
regulation of map kinase activityGO:00434051200.300
regulation of b cell differentiationGO:0045577230.288
negative regulation of b cell proliferationGO:0030889130.276
homeostasis of number of cellsGO:00488722100.275
lymphocyte differentiationGO:00300982420.274
actin polymerization or depolymerizationGO:0008154540.272
negative regulation of cellular component organizationGO:00511291940.272
associative learningGO:0008306610.267
response to platelet derived growth factorGO:003611960.265
positive regulation of lymphocyte differentiationGO:0045621610.263
negative regulation of hydrolase activityGO:0051346710.258
lipopolysaccharide mediated signaling pathwayGO:0031663250.256
regulation of cd8 positive alpha beta t cell activationGO:200118530.251
cation transportGO:00068123990.247
regulation of innate immune responseGO:0045088910.242
regulation of protein catabolic processGO:00421761080.241
regulation of mast cell proliferationGO:007066640.240
mast cell proliferationGO:007066240.240
b cell differentiationGO:0030183780.239
erk1 and erk2 cascadeGO:0070371770.236
fc receptor mediated inhibitory signaling pathwayGO:000277410.235
lymphocyte proliferationGO:00466511640.230
Mouse
ras protein signal transductionGO:0007265770.229
regulation of myeloid cell differentiationGO:0045637960.229
b cell homeostasisGO:0001782340.224
actin filament organizationGO:00070151130.223
dendritic cell apoptotic processGO:009704830.221
positive regulation of innate immune responseGO:0045089800.221
tyrosine phosphorylation of stat5 proteinGO:004250690.220
jak stat cascadeGO:0007259420.220
coagulationGO:0050817780.217
regulation of actin filament based processGO:0032970990.216
positive regulation of gamma delta t cell differentiationGO:004558860.214
positive regulation of cell projection organizationGO:0031346950.214
activation of innate immune responseGO:0002218560.214
actin cytoskeleton organizationGO:00300362200.214
lymphocyte apoptotic processGO:0070227540.212
regulation of organelle organizationGO:00330432890.211
Mouse
regulation of cell shapeGO:0008360390.208
toll like receptor 4 signaling pathwayGO:003414290.206
interleukin 4 productionGO:0032633240.206
cellular lipid metabolic processGO:00442553230.204
Human Mouse
learningGO:0007612980.204
negative regulation of phosphorylationGO:00423261660.200
exocrine system developmentGO:0035272450.198
positive regulation of dendritic cell apoptotic processGO:200067030.197
cellular response to lipidGO:00713961450.194
regulation of b cell apoptotic processGO:0002902130.192
filtration diaphragm assemblyGO:003605810.188
immune response regulating signaling pathwayGO:00027641250.185
positive regulation of phospholipase c activityGO:001086320.185
establishment of mitotic spindle orientationGO:0000132120.184
regulation of organelle assemblyGO:1902115190.184
positive regulation of defense responseGO:00313491240.183
cell adhesionGO:00071553290.182
myeloid leukocyte activationGO:0002274830.182
positive regulation of leukocyte differentiationGO:1902107860.182
regulation of endocytosisGO:0030100690.182
regulation of t cell differentiationGO:0045580830.181
hemostasisGO:0007599780.181
alpha beta t cell differentiationGO:0046632690.180
b cell apoptotic processGO:0001783190.179
positive regulation of protein localization to nucleusGO:1900182300.178
cellular response to growth factor stimulusGO:00713631970.176
regulation of transferase activityGO:00513382630.176
single organismal cell cell adhesionGO:00163371310.173
osteoclast developmentGO:003603590.172
gland developmentGO:00487323300.172
glial cell developmentGO:0021782540.171
defense response to other organismGO:00985421970.169
regulation of cell projection organizationGO:00313442060.168
regulation of protein localizationGO:00328802310.166
neutrophil differentiationGO:003022330.165
response to growth factorGO:00708481980.164
negative regulation of myeloid cell differentiationGO:0045638380.163
positive regulation of canonical wnt signaling pathwayGO:0090263290.160
mitotic cell cycle processGO:19030471590.159
Mouse
regulation of anatomical structure sizeGO:00900661780.155
uterus developmentGO:0060065160.152
extracellular structure organizationGO:00430621480.152
actin filament polymerizationGO:0030041440.150
organelle assemblyGO:00709251770.149
platelet activationGO:0030168400.148
response to organic cyclic compoundGO:00140701980.146
Rat
protein localization to nucleusGO:00345041210.146
i kappab kinase nf kappab signalingGO:0007249850.145
negative regulation of growthGO:0045926990.144
regulation of cytoskeleton organizationGO:00514931220.144
detection of mechanical stimulusGO:0050982270.143
regulation of mapk cascadeGO:00434082480.141
positive regulation of organelle organizationGO:00106381280.141
Mouse
response to transforming growth factor betaGO:0071559880.141
positive regulation of kinase activityGO:00336741550.139
regulation of ion transportGO:00432692150.138
cellular ketone metabolic processGO:0042180840.137
negative regulation of mast cell proliferationGO:007066710.135
macromolecule catabolic processGO:00090572810.134
regulation of gamma delta t cell differentiationGO:004558690.131
negative regulation of leukocyte differentiationGO:1902106510.129
wnt signaling pathwayGO:00160551880.129
calcium ion transportGO:00068161590.128
cytosolic calcium ion homeostasisGO:0051480700.125
calcium ion transport into cytosolGO:0060402480.125
positive regulation of neuron projection developmentGO:0010976790.123
lymphocyte homeostasisGO:0002260640.123
regulation of bindingGO:00510981110.122
Mouse
regulation of protein complex assemblyGO:0043254830.122
regulation of homotypic cell cell adhesionGO:0034110130.122
positive regulation of cellular amine metabolic processGO:003324050.122
digestive system developmentGO:00551232000.122
positive regulation of cell developmentGO:00107202370.120
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.119
cellular amino acid metabolic processGO:00065201030.119
cytokine productionGO:00018163190.118
Mouse
tissue remodelingGO:00487711020.117
cellular response to platelet derived growth factor stimulusGO:003612050.116
positive regulation of wnt signaling pathwayGO:0030177450.116
negative regulation of cell proliferationGO:00082852960.116
positive regulation of neuron differentiationGO:00456661410.114
membrane organizationGO:00610242450.113
osteoclast differentiationGO:0030316620.113
germ cell developmentGO:00072811850.112
Fly
maintenance of locationGO:0051235890.112
regulation of calcium ion transport into cytosolGO:0010522310.111
cell type specific apoptotic processGO:00972852680.110
cellular chemical homeostasisGO:00550822150.110
regulation of actin nucleationGO:005112540.110
cell fate commitmentGO:00451652100.110
learning or memoryGO:00076111480.110
Mouse
positive regulation of protein kinase activityGO:00458601440.110
negative regulation of lymphocyte activationGO:0051250910.110
mapk cascadeGO:00001652810.109
negative regulation of phosphate metabolic processGO:00459361840.108
peptidyl tyrosine modificationGO:00182121450.108
positive regulation of t cell activationGO:00508701010.107
leukocyte apoptotic processGO:0071887710.107
negative regulation of lymphocyte proliferationGO:0050672450.107
substrate adhesion dependent cell spreadingGO:0034446300.107
gliogenesisGO:00420631410.106
platelet aggregationGO:0070527200.106
columnar cuboidal epithelial cell differentiationGO:0002065820.106
Fly
leukocyte mediated immunityGO:00024431740.106
wound healingGO:00420601570.106
t cell activationGO:00421102890.105
negative regulation of myeloid leukocyte differentiationGO:0002762200.103
cellular response to molecule of bacterial originGO:0071219830.103
immunoglobulin mediated immune responseGO:0016064690.103
regulation of neuron differentiationGO:00456642810.103
actin filament bundle assemblyGO:0051017400.101
nucleoside catabolic processGO:00091642060.101
dendrite developmentGO:00163581150.101
leukocyte proliferationGO:00706611720.099
Mouse
positive regulation of protein modification processGO:00314012990.098
regulation of lymphocyte apoptotic processGO:0070228410.097
antigen receptor mediated signaling pathwayGO:0050851640.096
second messenger mediated signalingGO:0019932730.095
positive regulation of leukocyte apoptotic processGO:2000108210.095
embryonic organ morphogenesisGO:00485622760.095
gamma delta t cell differentiationGO:0042492110.094
regulation of antigen receptor mediated signaling pathwayGO:0050854290.093
Mouse
ion transmembrane transportGO:00342203610.093
granulocyte differentiationGO:0030851170.092
regulation of vesicle mediated transportGO:00606271390.092
Mouse
chemotaxisGO:00069352470.091
bone resorptionGO:0045453380.090
protein ubiquitinationGO:00165671710.090
regulation of leukocyte apoptotic processGO:2000106560.090
negative regulation of b cell activationGO:0050869270.090
regulation of cellular component biogenesisGO:00440871810.089
regulation of mast cell degranulationGO:0043304160.088
myeloid cell homeostasisGO:00022621140.087
regulation of protein bindingGO:0043393600.087
Mouse
regulation of gtp catabolic processGO:00331241130.087
gamma delta t cell activationGO:0046629130.086
regulation of cytoplasmic transportGO:19036491120.086
podosome assemblyGO:007180060.086
neuron migrationGO:00017641220.083
endoderm developmentGO:0007492450.082
cell junction organizationGO:0034330770.082
regulation of nucleotide catabolic processGO:00308111220.082
positive regulation of cytokine biosynthetic processGO:0042108400.082
cytoplasmic transportGO:00164822340.081
purine nucleotide metabolic processGO:00061633020.081
activation of phospholipase c activityGO:000720220.080
regulation of protein localization to nucleusGO:1900180600.080
dephosphorylationGO:00163111290.080
cd8 positive alpha beta t cell proliferationGO:003574010.079
extracellular matrix organizationGO:00301981470.079
negative regulation of mapk cascadeGO:0043409650.079
cellular response to biotic stimulusGO:0071216920.078
positive regulation of transferase activityGO:00513471670.078
response to inorganic substanceGO:0010035960.078
Rat
negative regulation of regulatory t cell differentiationGO:004559020.078
regionalizationGO:00030023370.077
oogenesisGO:0048477560.076
Fly
sequestering of calcium ionGO:0051208180.076
platelet degranulationGO:000257660.076
epithelial tube morphogenesisGO:00605623030.076
forebrain developmentGO:00309003020.076
Mouse
parallel actin filament bundle assemblyGO:003004620.076
actin cytoskeleton reorganizationGO:0031532210.075
negative regulation of adaptive immune responseGO:0002820250.074
regulation of cytokine productionGO:00018172660.074
Mouse
regulation of jak stat cascadeGO:0046425340.074
negative regulation of cellular amine metabolic processGO:003323910.073
cell cell junction assemblyGO:0007043270.073
branching involved in mammary gland duct morphogenesisGO:0060444270.073
cellular response to lipopolysaccharideGO:0071222770.073
regulation of cell adhesionGO:00301551540.072
sensory perception of mechanical stimulusGO:00509541070.072
response to ethanolGO:0045471180.072
regulation of wnt signaling pathwayGO:00301111230.072
integrin mediated signaling pathwayGO:0007229270.072
negative regulation of immune system processGO:00026832090.071
Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.070
Mouse Fly
salivary gland morphogenesisGO:0007435330.069
regulation of ras protein signal transductionGO:00465781140.069
positive regulation of secretion by cellGO:19035321140.069
Mouse
negative regulation of cell developmentGO:00107211690.068
regulation of cd8 positive alpha beta t cell proliferationGO:200056410.067
cell growthGO:00160491300.067
Fly
b cell mediated immunityGO:0019724710.067
detection of mechanical stimulus involved in sensory perceptionGO:0050974230.066
cellular component assembly involved in morphogenesisGO:00109271390.066
protein maturationGO:00516041760.066
cell junction assemblyGO:0034329520.066
negative regulation of b cell receptor signaling pathwayGO:005085940.066
Mouse
nucleoside triphosphate catabolic processGO:00091432050.065
protein localization to organelleGO:00333651850.065
positive regulation of programmed cell deathGO:00430682180.065
gtp catabolic processGO:00061841430.065
cellular response to transforming growth factor beta stimulusGO:0071560880.065
extrinsic apoptotic signaling pathwayGO:00971911260.065
chromatin modificationGO:00165681870.064
positive regulation of map kinase activityGO:0043406840.064
positive regulation of type i interferon mediated signaling pathwayGO:006034040.063
tolerance induction to self antigenGO:000251340.063
cell substrate adhesionGO:00315891300.063
g protein coupled receptor signaling pathwayGO:00071862430.063
Mouse
cognitionGO:00508901490.063
Mouse
negative regulation of cell activationGO:00508661110.063
germinal center formationGO:0002467160.062
positive regulation of interferon alpha productionGO:003272740.062
production of molecular mediator of immune responseGO:00024401030.062
regulation of myd88 independent toll like receptor signaling pathwayGO:003412710.062
female gamete generationGO:0007292740.061
Worm Fly
regulation of establishment of protein localizationGO:00702011810.061
tissue homeostasisGO:00018941150.061
response to alcoholGO:0097305480.061
t cell differentiationGO:00302171740.061
hematopoietic progenitor cell differentiationGO:00022441430.061
regulation of protein serine threonine kinase activityGO:00719001570.061
mast cell activationGO:0045576270.060
regulation of membrane potentialGO:00423911920.060
regulation of rho protein signal transductionGO:0035023710.060
negative regulation of protein catabolic processGO:0042177360.060
protein catabolic processGO:00301632210.060
regulation of cellular component sizeGO:00325351210.060
regulation of lymphocyte activationGO:00512492400.060
release of sequestered calcium ion into cytosolGO:0051209420.059
positive regulation of phospholipase activityGO:001051830.059
gastrulationGO:00073691160.059
regulation of g protein coupled receptor protein signaling pathwayGO:0008277370.059
Mouse
intracellular protein transportGO:00068862040.059
positive regulation of gtp catabolic processGO:0033126850.059
regulation of phosphatidylinositol 3 kinase activityGO:0043551140.059
synapse organizationGO:00508081250.059
intracellular receptor signaling pathwayGO:0030522740.058
negative regulation of cell adhesion mediated by integrinGO:003362920.058
regulation of cellular catabolic processGO:00313292420.057
interferon gamma productionGO:0032609670.057
negative regulation of cell projection organizationGO:0031345560.057
positive regulation of gamma delta t cell activationGO:004664560.056
positive regulation of cellular component biogenesisGO:0044089940.056
mammary gland epithelium developmentGO:0061180650.056
endodermal cell fate commitmentGO:0001711120.055
innate immune responseGO:00450871570.055
retrograde transport endosome to golgiGO:004214720.055
negative regulation of erk1 and erk2 cascadeGO:0070373210.055
negative regulation of cell adhesionGO:0007162450.055
multicellular organismal homeostasisGO:00488711640.054
positive regulation of cell motilityGO:20001471160.053
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.053
small molecule biosynthetic processGO:00442831320.053
myd88 independent toll like receptor signaling pathwayGO:000275630.052
positive regulation of actin nucleationGO:005112730.052
lateral inhibitionGO:004633110.052
positive regulation of hydrolase activityGO:00513451480.052
digestive tract morphogenesisGO:00485461470.051
humoral immune response mediated by circulating immunoglobulinGO:0002455140.051
cellular response to retinoic acidGO:0071300250.051
positive regulation of cell deathGO:00109422240.051
nitrogen compound transportGO:00717052710.051
mitotic spindle organizationGO:0007052100.051
striated muscle myosin thick filament assemblyGO:007168810.051
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.051
regulation of intracellular estrogen receptor signaling pathwayGO:003314680.050
cell cell junction organizationGO:0045216720.050
ribonucleoside catabolic processGO:00424542060.050
regulation of mast cell activationGO:0033003210.050
developmental programmed cell deathGO:0010623410.049
endoderm formationGO:0001706200.048
regulation of interleukin 6 productionGO:0032675550.048
response to retinoic acidGO:0032526560.048
mast cell degranulationGO:0043303190.048
stress activated mapk cascadeGO:0051403800.048
regulation of b cell activationGO:0050864810.047
negative regulation of interleukin 6 productionGO:0032715170.047
megakaryocyte differentiationGO:0030219260.047
peptidyl amino acid modificationGO:00181933360.047
Mouse
positive regulation of interleukin 12 productionGO:0032735210.047
Mouse
keratinocyte differentiationGO:0030216480.046
phagocytosisGO:0006909660.046
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.046
positive regulation of nervous system developmentGO:00519622210.046
circadian rhythmGO:00076231140.046
regulation of blood coagulationGO:0030193280.046
cell cell signaling involved in cell fate commitmentGO:0045168350.046
regulation of b cell proliferationGO:0030888390.045
negative regulation of intracellular signal transductionGO:19025321670.045
cd4 positive alpha beta t cell activationGO:0035710450.045
establishment of monopolar cell polarityGO:006116280.045
regulation of homeostatic processGO:00328441820.045
regulation of proteolysisGO:00301621640.045
negative regulation of homeostatic processGO:0032845710.045
positive regulation of mapk cascadeGO:00434101700.045
cd4 positive alpha beta t cell differentiationGO:0043367410.045
sensory organ morphogenesisGO:00905962420.045
cellularizationGO:000734910.044
regulation of reactive oxygen species metabolic processGO:2000377400.044
protein modification by small protein conjugation or removalGO:00706472070.044
monocarboxylic acid metabolic processGO:00327871910.044
positive regulation of b cell differentiationGO:0045579130.043
regulation of mast cell activation involved in immune responseGO:0033006170.043
regulation of lymphocyte proliferationGO:00506701170.043
regulation of stress activated mapk cascadeGO:0032872690.043
purine ribonucleotide metabolic processGO:00091502900.043
urogenital system developmentGO:00016552610.042
muscle cell differentiationGO:00426922610.042
Mouse
glycosyl compound catabolic processGO:19016582060.042
dendritic cell differentiationGO:0097028260.042
arp2 3 complex mediated actin nucleationGO:003431430.042
organic hydroxy compound metabolic processGO:19016152030.042
regulation of jnk cascadeGO:0046328620.042
gonad developmentGO:00084061410.041
fatty acid metabolic processGO:00066311210.041
regulation of defense response to virus by hostGO:005069180.041
regulation of cytokine secretionGO:0050707610.041
regulation of gamma delta t cell activationGO:004664390.041
negative regulation of ras protein signal transductionGO:0046580180.041
organonitrogen compound catabolic processGO:19015652640.041
negative regulation of leukocyte proliferationGO:0070664460.041
regulation of tyrosine phosphorylation of stat5 proteinGO:004252280.040
regulation of alpha beta t cell differentiationGO:0046637350.040
positive regulation of lipid kinase activityGO:0090218110.040
myeloid dendritic cell differentiationGO:0043011160.040
histamine transportGO:005160820.040
positive regulation of intracellular transportGO:0032388700.040
canonical wnt signaling pathwayGO:00600701300.040
regulation of multi organism processGO:00439001110.040
Mouse
toll like receptor 2 signaling pathwayGO:003413460.040
divalent inorganic cation homeostasisGO:00725071380.039
positive regulation of rho gtpase activityGO:0032321410.039
regulation of purine nucleotide metabolic processGO:19005421690.039
reactive oxygen species metabolic processGO:0072593840.039
fc receptor mediated stimulatory signaling pathwayGO:000243140.039
nk t cell differentiationGO:000186580.039
t cell proliferationGO:00420981200.039
morphogenesis of a polarized epitheliumGO:0001738370.039
positive regulation of antigen receptor mediated signaling pathwayGO:005085790.039
cellular metal ion homeostasisGO:00068751510.038
purine ribonucleoside triphosphate metabolic processGO:00092052200.038
neuron projection extensionGO:1990138640.038
segmentationGO:0035282930.038
regulation of synapse assemblyGO:0051963290.038
fibroblast growth factor receptor signaling pathwayGO:0008543460.038
t cell differentiation in thymusGO:0033077770.037
morphogenesis of a branching structureGO:00017632030.037
positive regulation of exocytosisGO:0045921200.037
Mouse
activation of rac gtpase activityGO:003286320.037
negative regulation of multi organism processGO:0043901680.037
positive regulation of apoptotic processGO:00430652170.037
negative regulation of toll like receptor 4 signaling pathwayGO:003414430.037
regulation of erk1 and erk2 cascadeGO:0070372710.037
cell maturationGO:00484691270.036
cellular ion homeostasisGO:00068731650.036
plasma membrane organizationGO:0007009900.036
cytokine secretionGO:0050663720.036
immune response regulating cell surface receptor signaling pathwayGO:0002768800.036
positive regulation of lipid metabolic processGO:0045834400.036
response to hypoxiaGO:0001666580.036
peptidyl lysine modificationGO:0018205770.036
cellular response to acid chemicalGO:0071229680.035
peptidyl tyrosine dephosphorylationGO:0035335230.035
regulation of lipase activityGO:0060191150.035
nucleocytoplasmic transportGO:00069131390.035
chromatin organizationGO:00063252060.035
anatomical structure homeostasisGO:00602491450.035
nucleotide catabolic processGO:00091662170.035
digestive tract developmentGO:00485651900.035
immune response activating cell surface receptor signaling pathwayGO:0002429720.034
regulation of metal ion transportGO:00109591060.034
axon guidanceGO:00074111410.034
formation of primary germ layerGO:0001704770.034
placenta developmentGO:00018901400.034
Mouse
protein secretionGO:00093061110.034
negative regulation of humoral immune response mediated by circulating immunoglobulinGO:000292430.033
tumor necrosis factor productionGO:0032640500.033
tumor necrosis factor superfamily cytokine productionGO:0071706510.033
positive regulation of protein complex assemblyGO:0031334450.033
nucleoside phosphate catabolic processGO:19012922220.033
regulation of hormone levelsGO:00108172110.033

Plcg2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.648
immune system diseaseDOID:291400.648
hematopoietic system diseaseDOID:7400.559
primary immunodeficiency diseaseDOID:61200.433
b cell deficiencyDOID:211500.263
agammaglobulinemiaDOID:258300.119
blood protein diseaseDOID:62000.119
common variable immunodeficiencyDOID:1217700.044