| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.960 | |
| regulation of toll like receptor signaling pathway | GO:0034121 | 20 | 0.880 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.830 | |
| innate immune response activating signal transduction | GO:0002758 | 50 | 0.808 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.804 | |
| negative regulation of kinase activity | GO:0033673 | 81 | 0.793 | |
| establishment of spindle localization | GO:0051293 | 19 | 0.782 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.772 | |
| establishment of mitotic spindle localization | GO:0040001 | 12 | 0.750 | |
| b cell activation | GO:0042113 | 161 | 0.744 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.739 | |
| establishment or maintenance of cell polarity | GO:0007163 | 86 | 0.723 | |
| toll like receptor signaling pathway | GO:0002224 | 38 | 0.718 | |
| spindle localization | GO:0051653 | 22 | 0.701 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.694 | |
| negative regulation of toll like receptor signaling pathway | GO:0034122 | 14 | 0.689 | |
| negative regulation of protein serine threonine kinase activity | GO:0071901 | 49 | 0.671 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.661 | |
| positive regulation of b cell receptor signaling pathway | GO:0050861 | 4 | 0.657 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.626 | |
| homotypic cell cell adhesion | GO:0034109 | 28 | 0.622 | |
| b cell receptor signaling pathway | GO:0050853 | 20 | 0.610 | |
| negative regulation of map kinase activity | GO:0043407 | 34 | 0.600 | |
| regulation of toll like receptor 2 signaling pathway | GO:0034135 | 3 | 0.590 | |
| establishment of spindle orientation | GO:0051294 | 15 | 0.586 | |
| regulation of myeloid leukocyte differentiation | GO:0002761 | 58 | 0.585 | |
| positive regulation of podosome assembly | GO:0071803 | 3 | 0.580 | |
| pattern recognition receptor signaling pathway | GO:0002221 | 47 | 0.575 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.567 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.565 | |
| adaptive immune response | GO:0002250 | 155 | 0.564 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.562 | |
| immune response inhibiting cell surface receptor signaling pathway | GO:0002767 | 3 | 0.559 | |
| regulation of actin cytoskeleton organization | GO:0032956 | 84 | 0.548 | |
| b cell proliferation | GO:0042100 | 53 | 0.536 | Mouse |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.526 | |
| regulation of toll like receptor 4 signaling pathway | GO:0034143 | 4 | 0.525 | |
| histamine production involved in inflammatory response | GO:0002349 | 1 | 0.520 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.516 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.482 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.473 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.469 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.459 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.448 | |
| erythrocyte differentiation | GO:0030218 | 88 | 0.429 | |
| negative regulation of transferase activity | GO:0051348 | 85 | 0.404 | |
| regulation of dendritic cell apoptotic process | GO:2000668 | 3 | 0.401 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.398 | |
| olfactory learning | GO:0008355 | 2 | 0.385 | |
| endodermal cell fate specification | GO:0001714 | 4 | 0.379 | |
| single organism cell adhesion | GO:0098602 | 156 | 0.379 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.375 | |
| amine metabolic process | GO:0009308 | 45 | 0.375 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.372 | |
| positive regulation of t cell differentiation | GO:0045582 | 52 | 0.365 | |
| immune response activating signal transduction | GO:0002757 | 116 | 0.364 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.362 | |
| immune response inhibiting signal transduction | GO:0002765 | 4 | 0.362 | |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.356 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.351 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.346 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.345 | |
| regulation of cell activation | GO:0050865 | 289 | 0.345 | |
| regulation of actin filament length | GO:0030832 | 45 | 0.343 | |
| negative regulation of synapse assembly | GO:0051964 | 3 | 0.339 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.338 | |
| regulation of podosome assembly | GO:0071801 | 3 | 0.336 | |
| regulation of neutrophil differentiation | GO:0045658 | 2 | 0.335 | |
| regulation of phospholipase c activity | GO:1900274 | 3 | 0.330 | |
| glycerolipid metabolic process | GO:0046486 | 122 | 0.328 | Human Mouse |
| regulation of calcium ion transport | GO:0051924 | 69 | 0.326 | |
| negative regulation of toll like receptor 2 signaling pathway | GO:0034136 | 3 | 0.321 | |
| axonogenesis | GO:0007409 | 274 | 0.315 | |
| microtubule based process | GO:0007017 | 236 | 0.315 | |
| detection of mechanical stimulus involved in sensory perception of pain | GO:0050966 | 4 | 0.308 | |
| regulation of erythrocyte differentiation | GO:0045646 | 23 | 0.307 | |
| organelle localization | GO:0051640 | 179 | 0.306 | |
| regulation of actin polymerization or depolymerization | GO:0008064 | 45 | 0.300 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.300 | |
| regulation of b cell differentiation | GO:0045577 | 23 | 0.288 | |
| negative regulation of b cell proliferation | GO:0030889 | 13 | 0.276 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.275 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.274 | |
| actin polymerization or depolymerization | GO:0008154 | 54 | 0.272 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.272 | |
| associative learning | GO:0008306 | 61 | 0.267 | |
| response to platelet derived growth factor | GO:0036119 | 6 | 0.265 | |
| positive regulation of lymphocyte differentiation | GO:0045621 | 61 | 0.263 | |
| negative regulation of hydrolase activity | GO:0051346 | 71 | 0.258 | |
| lipopolysaccharide mediated signaling pathway | GO:0031663 | 25 | 0.256 | |
| regulation of cd8 positive alpha beta t cell activation | GO:2001185 | 3 | 0.251 | |
| cation transport | GO:0006812 | 399 | 0.247 | |
| regulation of innate immune response | GO:0045088 | 91 | 0.242 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.241 | |
| regulation of mast cell proliferation | GO:0070666 | 4 | 0.240 | |
| mast cell proliferation | GO:0070662 | 4 | 0.240 | |
| b cell differentiation | GO:0030183 | 78 | 0.239 | |
| erk1 and erk2 cascade | GO:0070371 | 77 | 0.236 | |
| fc receptor mediated inhibitory signaling pathway | GO:0002774 | 1 | 0.235 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.230 | Mouse |
| ras protein signal transduction | GO:0007265 | 77 | 0.229 | |
| regulation of myeloid cell differentiation | GO:0045637 | 96 | 0.229 | |
| b cell homeostasis | GO:0001782 | 34 | 0.224 | |
| actin filament organization | GO:0007015 | 113 | 0.223 | |
| dendritic cell apoptotic process | GO:0097048 | 3 | 0.221 | |
| positive regulation of innate immune response | GO:0045089 | 80 | 0.221 | |
| tyrosine phosphorylation of stat5 protein | GO:0042506 | 9 | 0.220 | |
| jak stat cascade | GO:0007259 | 42 | 0.220 | |
| coagulation | GO:0050817 | 78 | 0.217 | |
| regulation of actin filament based process | GO:0032970 | 99 | 0.216 | |
| positive regulation of gamma delta t cell differentiation | GO:0045588 | 6 | 0.214 | |
| positive regulation of cell projection organization | GO:0031346 | 95 | 0.214 | |
| activation of innate immune response | GO:0002218 | 56 | 0.214 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.214 | |
| lymphocyte apoptotic process | GO:0070227 | 54 | 0.212 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.211 | Mouse |
| regulation of cell shape | GO:0008360 | 39 | 0.208 | |
| toll like receptor 4 signaling pathway | GO:0034142 | 9 | 0.206 | |
| interleukin 4 production | GO:0032633 | 24 | 0.206 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.204 | Human Mouse |
| learning | GO:0007612 | 98 | 0.204 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.200 | |
| exocrine system development | GO:0035272 | 45 | 0.198 | |
| positive regulation of dendritic cell apoptotic process | GO:2000670 | 3 | 0.197 | |
| cellular response to lipid | GO:0071396 | 145 | 0.194 | |
| regulation of b cell apoptotic process | GO:0002902 | 13 | 0.192 | |
| filtration diaphragm assembly | GO:0036058 | 1 | 0.188 | |
| immune response regulating signaling pathway | GO:0002764 | 125 | 0.185 | |
| positive regulation of phospholipase c activity | GO:0010863 | 2 | 0.185 | |
| establishment of mitotic spindle orientation | GO:0000132 | 12 | 0.184 | |
| regulation of organelle assembly | GO:1902115 | 19 | 0.184 | |
| positive regulation of defense response | GO:0031349 | 124 | 0.183 | |
| cell adhesion | GO:0007155 | 329 | 0.182 | |
| myeloid leukocyte activation | GO:0002274 | 83 | 0.182 | |
| positive regulation of leukocyte differentiation | GO:1902107 | 86 | 0.182 | |
| regulation of endocytosis | GO:0030100 | 69 | 0.182 | |
| regulation of t cell differentiation | GO:0045580 | 83 | 0.181 | |
| hemostasis | GO:0007599 | 78 | 0.181 | |
| alpha beta t cell differentiation | GO:0046632 | 69 | 0.180 | |
| b cell apoptotic process | GO:0001783 | 19 | 0.179 | |
| positive regulation of protein localization to nucleus | GO:1900182 | 30 | 0.178 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.176 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.176 | |
| single organismal cell cell adhesion | GO:0016337 | 131 | 0.173 | |
| osteoclast development | GO:0036035 | 9 | 0.172 | |
| gland development | GO:0048732 | 330 | 0.172 | |
| glial cell development | GO:0021782 | 54 | 0.171 | |
| defense response to other organism | GO:0098542 | 197 | 0.169 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.168 | |
| regulation of protein localization | GO:0032880 | 231 | 0.166 | |
| neutrophil differentiation | GO:0030223 | 3 | 0.165 | |
| response to growth factor | GO:0070848 | 198 | 0.164 | |
| negative regulation of myeloid cell differentiation | GO:0045638 | 38 | 0.163 | |
| positive regulation of canonical wnt signaling pathway | GO:0090263 | 29 | 0.160 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.159 | Mouse |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.155 | |
| uterus development | GO:0060065 | 16 | 0.152 | |
| extracellular structure organization | GO:0043062 | 148 | 0.152 | |
| actin filament polymerization | GO:0030041 | 44 | 0.150 | |
| organelle assembly | GO:0070925 | 177 | 0.149 | |
| platelet activation | GO:0030168 | 40 | 0.148 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.146 | Rat |
| protein localization to nucleus | GO:0034504 | 121 | 0.146 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 85 | 0.145 | |
| negative regulation of growth | GO:0045926 | 99 | 0.144 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.144 | |
| detection of mechanical stimulus | GO:0050982 | 27 | 0.143 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.141 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.141 | Mouse |
| response to transforming growth factor beta | GO:0071559 | 88 | 0.141 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.139 | |
| regulation of ion transport | GO:0043269 | 215 | 0.138 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.137 | |
| negative regulation of mast cell proliferation | GO:0070667 | 1 | 0.135 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.134 | |
| regulation of gamma delta t cell differentiation | GO:0045586 | 9 | 0.131 | |
| negative regulation of leukocyte differentiation | GO:1902106 | 51 | 0.129 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.129 | |
| calcium ion transport | GO:0006816 | 159 | 0.128 | |
| cytosolic calcium ion homeostasis | GO:0051480 | 70 | 0.125 | |
| calcium ion transport into cytosol | GO:0060402 | 48 | 0.125 | |
| positive regulation of neuron projection development | GO:0010976 | 79 | 0.123 | |
| lymphocyte homeostasis | GO:0002260 | 64 | 0.123 | |
| regulation of binding | GO:0051098 | 111 | 0.122 | Mouse |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.122 | |
| regulation of homotypic cell cell adhesion | GO:0034110 | 13 | 0.122 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.122 | |
| digestive system development | GO:0055123 | 200 | 0.122 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.120 | |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 145 | 0.119 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.119 | |
| cytokine production | GO:0001816 | 319 | 0.118 | Mouse |
| tissue remodeling | GO:0048771 | 102 | 0.117 | |
| cellular response to platelet derived growth factor stimulus | GO:0036120 | 5 | 0.116 | |
| positive regulation of wnt signaling pathway | GO:0030177 | 45 | 0.116 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.116 | |
| positive regulation of neuron differentiation | GO:0045666 | 141 | 0.114 | |
| membrane organization | GO:0061024 | 245 | 0.113 | |
| osteoclast differentiation | GO:0030316 | 62 | 0.113 | |
| germ cell development | GO:0007281 | 185 | 0.112 | Fly |
| maintenance of location | GO:0051235 | 89 | 0.112 | |
| regulation of calcium ion transport into cytosol | GO:0010522 | 31 | 0.111 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.110 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.110 | |
| regulation of actin nucleation | GO:0051125 | 4 | 0.110 | |
| cell fate commitment | GO:0045165 | 210 | 0.110 | |
| learning or memory | GO:0007611 | 148 | 0.110 | Mouse |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.110 | |
| negative regulation of lymphocyte activation | GO:0051250 | 91 | 0.110 | |
| mapk cascade | GO:0000165 | 281 | 0.109 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.108 | |
| peptidyl tyrosine modification | GO:0018212 | 145 | 0.108 | |
| positive regulation of t cell activation | GO:0050870 | 101 | 0.107 | |
| leukocyte apoptotic process | GO:0071887 | 71 | 0.107 | |
| negative regulation of lymphocyte proliferation | GO:0050672 | 45 | 0.107 | |
| substrate adhesion dependent cell spreading | GO:0034446 | 30 | 0.107 | |
| gliogenesis | GO:0042063 | 141 | 0.106 | |
| platelet aggregation | GO:0070527 | 20 | 0.106 | |
| columnar cuboidal epithelial cell differentiation | GO:0002065 | 82 | 0.106 | Fly |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.106 | |
| wound healing | GO:0042060 | 157 | 0.106 | |
| t cell activation | GO:0042110 | 289 | 0.105 | |
| negative regulation of myeloid leukocyte differentiation | GO:0002762 | 20 | 0.103 | |
| cellular response to molecule of bacterial origin | GO:0071219 | 83 | 0.103 | |
| immunoglobulin mediated immune response | GO:0016064 | 69 | 0.103 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.103 | |
| actin filament bundle assembly | GO:0051017 | 40 | 0.101 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.101 | |
| dendrite development | GO:0016358 | 115 | 0.101 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.099 | Mouse |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.098 | |
| regulation of lymphocyte apoptotic process | GO:0070228 | 41 | 0.097 | |
| antigen receptor mediated signaling pathway | GO:0050851 | 64 | 0.096 | |
| second messenger mediated signaling | GO:0019932 | 73 | 0.095 | |
| positive regulation of leukocyte apoptotic process | GO:2000108 | 21 | 0.095 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.095 | |
| gamma delta t cell differentiation | GO:0042492 | 11 | 0.094 | |
| regulation of antigen receptor mediated signaling pathway | GO:0050854 | 29 | 0.093 | Mouse |
| ion transmembrane transport | GO:0034220 | 361 | 0.093 | |
| granulocyte differentiation | GO:0030851 | 17 | 0.092 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.092 | Mouse |
| chemotaxis | GO:0006935 | 247 | 0.091 | |
| bone resorption | GO:0045453 | 38 | 0.090 | |
| protein ubiquitination | GO:0016567 | 171 | 0.090 | |
| regulation of leukocyte apoptotic process | GO:2000106 | 56 | 0.090 | |
| negative regulation of b cell activation | GO:0050869 | 27 | 0.090 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.089 | |
| regulation of mast cell degranulation | GO:0043304 | 16 | 0.088 | |
| myeloid cell homeostasis | GO:0002262 | 114 | 0.087 | |
| regulation of protein binding | GO:0043393 | 60 | 0.087 | Mouse |
| regulation of gtp catabolic process | GO:0033124 | 113 | 0.087 | |
| gamma delta t cell activation | GO:0046629 | 13 | 0.086 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.086 | |
| podosome assembly | GO:0071800 | 6 | 0.086 | |
| neuron migration | GO:0001764 | 122 | 0.083 | |
| endoderm development | GO:0007492 | 45 | 0.082 | |
| cell junction organization | GO:0034330 | 77 | 0.082 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.082 | |
| positive regulation of cytokine biosynthetic process | GO:0042108 | 40 | 0.082 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.081 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.081 | |
| activation of phospholipase c activity | GO:0007202 | 2 | 0.080 | |
| regulation of protein localization to nucleus | GO:1900180 | 60 | 0.080 | |
| dephosphorylation | GO:0016311 | 129 | 0.080 | |
| cd8 positive alpha beta t cell proliferation | GO:0035740 | 1 | 0.079 | |
| extracellular matrix organization | GO:0030198 | 147 | 0.079 | |
| negative regulation of mapk cascade | GO:0043409 | 65 | 0.079 | |
| cellular response to biotic stimulus | GO:0071216 | 92 | 0.078 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.078 | |
| response to inorganic substance | GO:0010035 | 96 | 0.078 | Rat |
| negative regulation of regulatory t cell differentiation | GO:0045590 | 2 | 0.078 | |
| regionalization | GO:0003002 | 337 | 0.077 | |
| oogenesis | GO:0048477 | 56 | 0.076 | Fly |
| sequestering of calcium ion | GO:0051208 | 18 | 0.076 | |
| platelet degranulation | GO:0002576 | 6 | 0.076 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.076 | |
| forebrain development | GO:0030900 | 302 | 0.076 | Mouse |
| parallel actin filament bundle assembly | GO:0030046 | 2 | 0.076 | |
| actin cytoskeleton reorganization | GO:0031532 | 21 | 0.075 | |
| negative regulation of adaptive immune response | GO:0002820 | 25 | 0.074 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.074 | Mouse |
| regulation of jak stat cascade | GO:0046425 | 34 | 0.074 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.073 | |
| cell cell junction assembly | GO:0007043 | 27 | 0.073 | |
| branching involved in mammary gland duct morphogenesis | GO:0060444 | 27 | 0.073 | |
| cellular response to lipopolysaccharide | GO:0071222 | 77 | 0.073 | |
| regulation of cell adhesion | GO:0030155 | 154 | 0.072 | |
| sensory perception of mechanical stimulus | GO:0050954 | 107 | 0.072 | |
| response to ethanol | GO:0045471 | 18 | 0.072 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.072 | |
| integrin mediated signaling pathway | GO:0007229 | 27 | 0.072 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.071 | Mouse |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.070 | Mouse Fly |
| salivary gland morphogenesis | GO:0007435 | 33 | 0.069 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.069 | |
| positive regulation of secretion by cell | GO:1903532 | 114 | 0.069 | Mouse |
| negative regulation of cell development | GO:0010721 | 169 | 0.068 | |
| regulation of cd8 positive alpha beta t cell proliferation | GO:2000564 | 1 | 0.067 | |
| cell growth | GO:0016049 | 130 | 0.067 | Fly |
| b cell mediated immunity | GO:0019724 | 71 | 0.067 | |
| detection of mechanical stimulus involved in sensory perception | GO:0050974 | 23 | 0.066 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 139 | 0.066 | |
| protein maturation | GO:0051604 | 176 | 0.066 | |
| cell junction assembly | GO:0034329 | 52 | 0.066 | |
| negative regulation of b cell receptor signaling pathway | GO:0050859 | 4 | 0.066 | Mouse |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.065 | |
| protein localization to organelle | GO:0033365 | 185 | 0.065 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.065 | |
| gtp catabolic process | GO:0006184 | 143 | 0.065 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 88 | 0.065 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.065 | |
| chromatin modification | GO:0016568 | 187 | 0.064 | |
| positive regulation of map kinase activity | GO:0043406 | 84 | 0.064 | |
| positive regulation of type i interferon mediated signaling pathway | GO:0060340 | 4 | 0.063 | |
| tolerance induction to self antigen | GO:0002513 | 4 | 0.063 | |
| cell substrate adhesion | GO:0031589 | 130 | 0.063 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.063 | Mouse |
| cognition | GO:0050890 | 149 | 0.063 | Mouse |
| negative regulation of cell activation | GO:0050866 | 111 | 0.063 | |
| germinal center formation | GO:0002467 | 16 | 0.062 | |
| positive regulation of interferon alpha production | GO:0032727 | 4 | 0.062 | |
| production of molecular mediator of immune response | GO:0002440 | 103 | 0.062 | |
| regulation of myd88 independent toll like receptor signaling pathway | GO:0034127 | 1 | 0.062 | |
| female gamete generation | GO:0007292 | 74 | 0.061 | Worm Fly |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.061 | |
| tissue homeostasis | GO:0001894 | 115 | 0.061 | |
| response to alcohol | GO:0097305 | 48 | 0.061 | |
| t cell differentiation | GO:0030217 | 174 | 0.061 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.061 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.061 | |
| mast cell activation | GO:0045576 | 27 | 0.060 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.060 | |
| regulation of rho protein signal transduction | GO:0035023 | 71 | 0.060 | |
| negative regulation of protein catabolic process | GO:0042177 | 36 | 0.060 | |
| protein catabolic process | GO:0030163 | 221 | 0.060 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.060 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.060 | |
| release of sequestered calcium ion into cytosol | GO:0051209 | 42 | 0.059 | |
| positive regulation of phospholipase activity | GO:0010518 | 3 | 0.059 | |
| gastrulation | GO:0007369 | 116 | 0.059 | |
| regulation of g protein coupled receptor protein signaling pathway | GO:0008277 | 37 | 0.059 | Mouse |
| intracellular protein transport | GO:0006886 | 204 | 0.059 | |
| positive regulation of gtp catabolic process | GO:0033126 | 85 | 0.059 | |
| regulation of phosphatidylinositol 3 kinase activity | GO:0043551 | 14 | 0.059 | |
| synapse organization | GO:0050808 | 125 | 0.059 | |
| intracellular receptor signaling pathway | GO:0030522 | 74 | 0.058 | |
| negative regulation of cell adhesion mediated by integrin | GO:0033629 | 2 | 0.058 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.057 | |
| interferon gamma production | GO:0032609 | 67 | 0.057 | |
| negative regulation of cell projection organization | GO:0031345 | 56 | 0.057 | |
| positive regulation of gamma delta t cell activation | GO:0046645 | 6 | 0.056 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 94 | 0.056 | |
| mammary gland epithelium development | GO:0061180 | 65 | 0.056 | |
| endodermal cell fate commitment | GO:0001711 | 12 | 0.055 | |
| innate immune response | GO:0045087 | 157 | 0.055 | |
| retrograde transport endosome to golgi | GO:0042147 | 2 | 0.055 | |
| negative regulation of erk1 and erk2 cascade | GO:0070373 | 21 | 0.055 | |
| negative regulation of cell adhesion | GO:0007162 | 45 | 0.055 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.054 | |
| positive regulation of cell motility | GO:2000147 | 116 | 0.053 | |
| regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002822 | 87 | 0.053 | |
| small molecule biosynthetic process | GO:0044283 | 132 | 0.053 | |
| myd88 independent toll like receptor signaling pathway | GO:0002756 | 3 | 0.052 | |
| positive regulation of actin nucleation | GO:0051127 | 3 | 0.052 | |
| lateral inhibition | GO:0046331 | 1 | 0.052 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.052 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.051 | |
| humoral immune response mediated by circulating immunoglobulin | GO:0002455 | 14 | 0.051 | |
| cellular response to retinoic acid | GO:0071300 | 25 | 0.051 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.051 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.051 | |
| mitotic spindle organization | GO:0007052 | 10 | 0.051 | |
| striated muscle myosin thick filament assembly | GO:0071688 | 1 | 0.051 | |
| positive regulation of peptidyl tyrosine phosphorylation | GO:0050731 | 61 | 0.051 | |
| regulation of intracellular estrogen receptor signaling pathway | GO:0033146 | 8 | 0.050 | |
| cell cell junction organization | GO:0045216 | 72 | 0.050 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.050 | |
| regulation of mast cell activation | GO:0033003 | 21 | 0.050 | |
| developmental programmed cell death | GO:0010623 | 41 | 0.049 | |
| endoderm formation | GO:0001706 | 20 | 0.048 | |
| regulation of interleukin 6 production | GO:0032675 | 55 | 0.048 | |
| response to retinoic acid | GO:0032526 | 56 | 0.048 | |
| mast cell degranulation | GO:0043303 | 19 | 0.048 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.048 | |
| regulation of b cell activation | GO:0050864 | 81 | 0.047 | |
| negative regulation of interleukin 6 production | GO:0032715 | 17 | 0.047 | |
| megakaryocyte differentiation | GO:0030219 | 26 | 0.047 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.047 | Mouse |
| positive regulation of interleukin 12 production | GO:0032735 | 21 | 0.047 | Mouse |
| keratinocyte differentiation | GO:0030216 | 48 | 0.046 | |
| phagocytosis | GO:0006909 | 66 | 0.046 | |
| negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002823 | 23 | 0.046 | |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.046 | |
| circadian rhythm | GO:0007623 | 114 | 0.046 | |
| regulation of blood coagulation | GO:0030193 | 28 | 0.046 | |
| cell cell signaling involved in cell fate commitment | GO:0045168 | 35 | 0.046 | |
| regulation of b cell proliferation | GO:0030888 | 39 | 0.045 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.045 | |
| cd4 positive alpha beta t cell activation | GO:0035710 | 45 | 0.045 | |
| establishment of monopolar cell polarity | GO:0061162 | 8 | 0.045 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.045 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.045 | |
| negative regulation of homeostatic process | GO:0032845 | 71 | 0.045 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.045 | |
| cd4 positive alpha beta t cell differentiation | GO:0043367 | 41 | 0.045 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.045 | |
| cellularization | GO:0007349 | 1 | 0.044 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.044 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.044 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.044 | |
| positive regulation of b cell differentiation | GO:0045579 | 13 | 0.043 | |
| regulation of mast cell activation involved in immune response | GO:0033006 | 17 | 0.043 | |
| regulation of lymphocyte proliferation | GO:0050670 | 117 | 0.043 | |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 0.043 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.043 | |
| urogenital system development | GO:0001655 | 261 | 0.042 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.042 | Mouse |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.042 | |
| dendritic cell differentiation | GO:0097028 | 26 | 0.042 | |
| arp2 3 complex mediated actin nucleation | GO:0034314 | 3 | 0.042 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.042 | |
| regulation of jnk cascade | GO:0046328 | 62 | 0.042 | |
| gonad development | GO:0008406 | 141 | 0.041 | |
| fatty acid metabolic process | GO:0006631 | 121 | 0.041 | |
| regulation of defense response to virus by host | GO:0050691 | 8 | 0.041 | |
| regulation of cytokine secretion | GO:0050707 | 61 | 0.041 | |
| regulation of gamma delta t cell activation | GO:0046643 | 9 | 0.041 | |
| negative regulation of ras protein signal transduction | GO:0046580 | 18 | 0.041 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.041 | |
| negative regulation of leukocyte proliferation | GO:0070664 | 46 | 0.041 | |
| regulation of tyrosine phosphorylation of stat5 protein | GO:0042522 | 8 | 0.040 | |
| regulation of alpha beta t cell differentiation | GO:0046637 | 35 | 0.040 | |
| positive regulation of lipid kinase activity | GO:0090218 | 11 | 0.040 | |
| myeloid dendritic cell differentiation | GO:0043011 | 16 | 0.040 | |
| histamine transport | GO:0051608 | 2 | 0.040 | |
| positive regulation of intracellular transport | GO:0032388 | 70 | 0.040 | |
| canonical wnt signaling pathway | GO:0060070 | 130 | 0.040 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.040 | Mouse |
| toll like receptor 2 signaling pathway | GO:0034134 | 6 | 0.040 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.039 | |
| positive regulation of rho gtpase activity | GO:0032321 | 41 | 0.039 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.039 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.039 | |
| fc receptor mediated stimulatory signaling pathway | GO:0002431 | 4 | 0.039 | |
| nk t cell differentiation | GO:0001865 | 8 | 0.039 | |
| t cell proliferation | GO:0042098 | 120 | 0.039 | |
| morphogenesis of a polarized epithelium | GO:0001738 | 37 | 0.039 | |
| positive regulation of antigen receptor mediated signaling pathway | GO:0050857 | 9 | 0.039 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.038 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.038 | |
| neuron projection extension | GO:1990138 | 64 | 0.038 | |
| segmentation | GO:0035282 | 93 | 0.038 | |
| regulation of synapse assembly | GO:0051963 | 29 | 0.038 | |
| fibroblast growth factor receptor signaling pathway | GO:0008543 | 46 | 0.038 | |
| t cell differentiation in thymus | GO:0033077 | 77 | 0.037 | |
| morphogenesis of a branching structure | GO:0001763 | 203 | 0.037 | |
| positive regulation of exocytosis | GO:0045921 | 20 | 0.037 | Mouse |
| activation of rac gtpase activity | GO:0032863 | 2 | 0.037 | |
| negative regulation of multi organism process | GO:0043901 | 68 | 0.037 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.037 | |
| negative regulation of toll like receptor 4 signaling pathway | GO:0034144 | 3 | 0.037 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 71 | 0.037 | |
| cell maturation | GO:0048469 | 127 | 0.036 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.036 | |
| plasma membrane organization | GO:0007009 | 90 | 0.036 | |
| cytokine secretion | GO:0050663 | 72 | 0.036 | |
| immune response regulating cell surface receptor signaling pathway | GO:0002768 | 80 | 0.036 | |
| positive regulation of lipid metabolic process | GO:0045834 | 40 | 0.036 | |
| response to hypoxia | GO:0001666 | 58 | 0.036 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.036 | |
| cellular response to acid chemical | GO:0071229 | 68 | 0.035 | |
| peptidyl tyrosine dephosphorylation | GO:0035335 | 23 | 0.035 | |
| regulation of lipase activity | GO:0060191 | 15 | 0.035 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.035 | |
| chromatin organization | GO:0006325 | 206 | 0.035 | |
| anatomical structure homeostasis | GO:0060249 | 145 | 0.035 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.035 | |
| digestive tract development | GO:0048565 | 190 | 0.035 | |
| immune response activating cell surface receptor signaling pathway | GO:0002429 | 72 | 0.034 | |
| regulation of metal ion transport | GO:0010959 | 106 | 0.034 | |
| axon guidance | GO:0007411 | 141 | 0.034 | |
| formation of primary germ layer | GO:0001704 | 77 | 0.034 | |
| placenta development | GO:0001890 | 140 | 0.034 | Mouse |
| protein secretion | GO:0009306 | 111 | 0.034 | |
| negative regulation of humoral immune response mediated by circulating immunoglobulin | GO:0002924 | 3 | 0.033 | |
| tumor necrosis factor production | GO:0032640 | 50 | 0.033 | |
| tumor necrosis factor superfamily cytokine production | GO:0071706 | 51 | 0.033 | |
| positive regulation of protein complex assembly | GO:0031334 | 45 | 0.033 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.033 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.033 | |
