Mus musculus

0 known processes

Arhgef4

Rho guanine nucleotide exchange factor (GEF) 4

(Aliases: ENSMUSG00000070955,9330140K16Rik,Asef)

Arhgef4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amine metabolic processGO:0044106440.064
cellular ketone metabolic processGO:0042180840.054
regulation of cellular amine metabolic processGO:0033238200.054
nucleobase containing small molecule metabolic processGO:00550863520.053
Human
ras protein signal transductionGO:0007265770.052
purine nucleotide metabolic processGO:00061633020.052
Human
regulation of cellular amino acid metabolic processGO:000652150.051
amine metabolic processGO:0009308450.051
regulation of cellular ketone metabolic processGO:0010565660.049
male gamete generationGO:00482322850.048
cellular amino acid metabolic processGO:00065201030.046
nucleoside phosphate metabolic processGO:00067533380.045
Human
cellular lipid metabolic processGO:00442553230.041
nucleotide metabolic processGO:00091173320.040
Human
small gtpase mediated signal transductionGO:0007264970.037
regulation of membrane potentialGO:00423911920.037
positive regulation of cellular amino acid metabolic processGO:004576430.036
regulation of organelle organizationGO:00330432890.036
peptidyl amino acid modificationGO:00181933360.036
regulation of kinase activityGO:00435492490.035
cellular nitrogen compound catabolic processGO:00442702800.035
Human
organonitrogen compound biosynthetic processGO:19015661920.034
organic cyclic compound catabolic processGO:19013612950.034
Human
transmembrane transportGO:00550854120.033
ribonucleotide metabolic processGO:00092592910.033
Human
purine containing compound metabolic processGO:00725213110.033
Human
gtp catabolic processGO:00061841430.031
Human
cation transportGO:00068123990.031
negative regulation of protein metabolic processGO:00512482820.030
ribose phosphate metabolic processGO:00196932910.030
Human
protein modification by small protein conjugation or removalGO:00706472070.030
purine ribonucleotide metabolic processGO:00091502900.030
Human
spermatogenesisGO:00072832840.030
negative regulation of cellular protein metabolic processGO:00322692470.030
regulation of protein kinase activityGO:00458592320.029
regulation of hydrolase activityGO:00513362460.029
Human
ion transmembrane transportGO:00342203610.029
glycosyl compound catabolic processGO:19016582060.028
Human
positive regulation of protein modification processGO:00314012990.028
nucleoside triphosphate metabolic processGO:00091412300.028
Human
positive regulation of cellular amine metabolic processGO:003324050.028
heterocycle catabolic processGO:00467002800.028
Human
carbohydrate derivative catabolic processGO:19011362310.028
Human
rho protein signal transductionGO:0007266320.028
macromolecule catabolic processGO:00090572810.028
regulation of cellular catabolic processGO:00313292420.028
Human
purine ribonucleoside triphosphate metabolic processGO:00092052200.028
Human
regulation of secretionGO:00510462740.028
regulation of transferase activityGO:00513382630.028
response to organonitrogen compoundGO:00102432460.027
apoptotic signaling pathwayGO:00971903060.027
t cell activationGO:00421102890.027
regulation of secretion by cellGO:19035302490.027
protein modification by small protein conjugationGO:00324461870.027
oxidation reduction processGO:00551143420.027
membrane organizationGO:00610242450.027
regulation of neuron differentiationGO:00456642810.027
axonogenesisGO:00074092740.027
dna metabolic processGO:00062593030.026
ribonucleoside triphosphate catabolic processGO:00092031990.026
Human
regulation of lymphocyte activationGO:00512492400.026
mapk cascadeGO:00001652810.026
purine nucleoside metabolic processGO:00422782410.026
Human
glycosyl compound metabolic processGO:19016572460.026
Human
purine nucleoside catabolic processGO:00061522050.026
Human
ribonucleotide catabolic processGO:00092612080.025
Human
purine nucleoside triphosphate metabolic processGO:00091442260.025
Human
regulation of cell activationGO:00508652890.025
purine ribonucleoside metabolic processGO:00461282410.025
Human
negative regulation of molecular functionGO:00440922580.025
ribonucleoside catabolic processGO:00424542060.025
Human
nucleoside phosphate catabolic processGO:19012922220.025
Human
leukocyte differentiationGO:00025213420.025
regulation of cell projection organizationGO:00313442060.024
protein catabolic processGO:00301632210.024
nucleoside metabolic processGO:00091162460.024
Human
positive regulation of cell developmentGO:00107202370.024
ribonucleoside triphosphate metabolic processGO:00091992200.024
Human
aromatic compound catabolic processGO:00194392860.024
Human
synaptic transmissionGO:00072683290.024
purine nucleoside triphosphate catabolic processGO:00091462030.023
Human
purine ribonucleoside catabolic processGO:00461302050.023
Human
carbohydrate derivative biosynthetic processGO:19011371830.023
negative regulation of cell proliferationGO:00082852960.023
muscle tissue developmentGO:00605373080.023
nucleoside catabolic processGO:00091642060.023
Human
regulation of cell cycleGO:00517262810.023
organophosphate catabolic processGO:00464342320.022
Human
regulation of apoptotic signaling pathwayGO:20012331970.022
positive regulation of protein phosphorylationGO:00019342420.022
cation transmembrane transportGO:00986552660.022
muscle cell differentiationGO:00426922610.022
sensory perceptionGO:00076002450.022
carbohydrate metabolic processGO:00059752300.022
negative regulation of cellular component organizationGO:00511291940.022
cellular macromolecule catabolic processGO:00442652060.022
purine ribonucleoside triphosphate catabolic processGO:00092071990.022
Human
protein ubiquitinationGO:00165671710.022
regulation of nucleotide metabolic processGO:00061401690.022
Human
regulation of hormone levelsGO:00108172110.021
regulation of neuron projection developmentGO:00109751690.021
dephosphorylationGO:00163111290.021
regulation of purine nucleotide catabolic processGO:00331211220.021
Human
cell adhesionGO:00071553290.021
negative regulation of phosphorylationGO:00423261660.021
nitrogen compound transportGO:00717052710.020
chemotaxisGO:00069352470.020
epidermis developmentGO:00085441870.020
organonitrogen compound catabolic processGO:19015652640.020
Human
cellular homeostasisGO:00197252400.020
ribonucleoside metabolic processGO:00091192450.020
Human
gland developmentGO:00487323300.020
fertilizationGO:00095661270.020
regulation of cell migrationGO:00303342190.020
organophosphate biosynthetic processGO:00904071220.020
skin developmentGO:00435882200.020
monocarboxylic acid metabolic processGO:00327871910.019
positive regulation of cellular catabolic processGO:00313311480.019
Human
cellular response to lipidGO:00713961450.019
organic hydroxy compound metabolic processGO:19016152030.019
positive regulation of hydrolase activityGO:00513451480.019
Human
purine nucleotide catabolic processGO:00061952110.019
Human
nucleoside triphosphate catabolic processGO:00091432050.019
Human
regulation of cell motilityGO:20001452360.019
immune effector processGO:00022523210.019
nucleotide catabolic processGO:00091662170.019
Human
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.019
purine containing compound catabolic processGO:00725232130.019
Human
negative regulation of cell developmentGO:00107211690.019
embryonic organ morphogenesisGO:00485622760.019
lymphocyte differentiationGO:00300982420.019
positive regulation of kinase activityGO:00336741550.019
cellular chemical homeostasisGO:00550822150.019
endomembrane system organizationGO:00102561470.019
germ cell developmentGO:00072811850.018
response to organic cyclic compoundGO:00140701980.018
regulation of purine nucleotide metabolic processGO:19005421690.018
Human
myeloid cell differentiationGO:00300992330.018
striated muscle tissue developmentGO:00147062930.018
cognitionGO:00508901490.018
skeletal system developmentGO:00015013560.018
protein maturationGO:00516041760.018
positive regulation of organelle organizationGO:00106381280.018
forebrain developmentGO:00309003020.018
multicellular organismal signalingGO:0035637910.018
g protein coupled receptor signaling pathwayGO:00071862430.018
positive regulation of cell deathGO:00109422240.018
positive regulation of nervous system developmentGO:00519622210.018
purine ribonucleotide catabolic processGO:00091542080.018
Human
cytoplasmic transportGO:00164822340.018
microtubule based processGO:00070172360.018
wound healingGO:00420601570.018
regulation of proteolysisGO:00301621640.018
negative regulation of protein modification processGO:00314001630.018
positive regulation of nucleotide metabolic processGO:00459811140.018
Human
organelle localizationGO:00516401790.017
positive regulation of purine nucleotide metabolic processGO:19005441140.017
Human
regulation of ion transportGO:00432692150.017
regulation of mapk cascadeGO:00434082480.017
organelle fissionGO:00482851700.017
negative regulation of protein phosphorylationGO:00019331260.017
regulation of vesicle mediated transportGO:00606271390.017
divalent inorganic cation transportGO:00725111780.017
small molecule biosynthetic processGO:00442831320.017
regulation of cell morphogenesis involved in differentiationGO:00107691510.017
cellular response to dna damage stimulusGO:00069742070.017
developmental maturationGO:00217001930.017
lipid biosynthetic processGO:00086101790.017
blood circulationGO:00080151950.017
cellular response to organonitrogen compoundGO:00714171450.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.017
maintenance of locationGO:0051235890.017
guanosine containing compound catabolic processGO:19010691440.017
Human
cytokine productionGO:00018163190.016
camera type eye developmentGO:00430102660.016
endocytosisGO:00068971680.016
fat cell differentiationGO:00454441600.016
homeostasis of number of cellsGO:00488722100.016
gtp metabolic processGO:00460391440.016
Human
phospholipid metabolic processGO:0006644870.016
regulation of body fluid levelsGO:00508781620.016
regulation of nucleotide catabolic processGO:00308111220.016
Human
cation homeostasisGO:00550802120.016
response to radiationGO:00093141650.016
guanosine containing compound metabolic processGO:19010681440.016
Human
inorganic cation transmembrane transportGO:00986622070.016
regulation of anatomical structure sizeGO:00900661780.016
regulation of cellular component biogenesisGO:00440871810.016
compound eye developmentGO:004874910.015
chromatin organizationGO:00063252060.015
multicellular organismal homeostasisGO:00488711640.015
response to peptideGO:19016521360.015
carbohydrate homeostasisGO:00335001280.015
cell type specific apoptotic processGO:00972852680.015
regulation of t cell activationGO:00508631700.015
learning or memoryGO:00076111480.015
glycoprotein metabolic processGO:00091001160.015
amide transportGO:00428861380.015
cell substrate adhesionGO:00315891300.015
regulation of cellular response to stressGO:00801351590.015
glucose homeostasisGO:00425931280.015
actin filament organizationGO:00070151130.015
positive regulation of secretionGO:00510471300.015
intracellular protein transportGO:00068862040.015
protein processingGO:00164851630.015
positive regulation of transferase activityGO:00513471670.015
plasma membrane organizationGO:0007009900.015
leukocyte proliferationGO:00706611720.015
histone modificationGO:00165701590.015
wnt signaling pathwayGO:00160551880.015
regulation of ras protein signal transductionGO:00465781140.015
Human
cell growthGO:00160491300.015
single organism cell adhesionGO:00986021560.015
regulation of lipid metabolic processGO:00192161180.015
muscle system processGO:00030121410.015
inorganic ion transmembrane transportGO:00986602340.015
regulation of cell cycle processGO:00105641600.015
sequestering of calcium ionGO:0051208180.014
regulation of cytoskeleton organizationGO:00514931220.014
mitotic cell cycleGO:00002781950.014
regulation of nucleoside metabolic processGO:00091181300.014
Human
rhythmic processGO:00485111740.014
regulation of cellular component sizeGO:00325351210.014
negative regulation of cellular amino acid metabolic processGO:004576300.014
anion transportGO:00068201770.014
hematopoietic progenitor cell differentiationGO:00022441430.014
single organismal cell cell adhesionGO:00163371310.014
skeletal muscle organ developmentGO:00605381630.014
covalent chromatin modificationGO:00165691630.014
sulfur compound metabolic processGO:00067901000.014
posttranscriptional regulation of gene expressionGO:00106081550.014
actin cytoskeleton organizationGO:00300362200.014
positive regulation of mapk cascadeGO:00434101700.014
regulation of protein localizationGO:00328802310.014
respiratory system developmentGO:00605411900.014
positive regulation of cellular component biogenesisGO:0044089940.014
reactive oxygen species metabolic processGO:0072593840.014
positive regulation of protein kinase activityGO:00458601440.014
nuclear divisionGO:00002801580.014
ubiquitin dependent protein catabolic processGO:00065111290.014
ossificationGO:00015032160.014
peptide transportGO:00158331330.014
sequestering of metal ionGO:0051238190.014
response to acid chemicalGO:00011011110.014
regulation of feeding behaviorGO:006025930.014
peptidyl tyrosine phosphorylationGO:00181081430.014
protein localization to organelleGO:00333651850.014
response to extracellular stimulusGO:00099911270.013
response to light stimulusGO:00094161350.013
lymphocyte proliferationGO:00466511640.013
divalent inorganic cation homeostasisGO:00725071380.013
response to inorganic substanceGO:0010035960.013
negative regulation of intracellular signal transductionGO:19025321670.013
calcium ion transportGO:00068161590.013
negative regulation of phosphorus metabolic processGO:00105631840.013
cellular protein catabolic processGO:00442571550.013
positive regulation of nucleoside metabolic processGO:0045979910.013
Human
regulation of intracellular transportGO:00323861590.013
cellular response to hormone stimulusGO:00328701500.013
regulation of synaptic growth at neuromuscular junctionGO:000858240.013
positive regulation of secretion by cellGO:19035321140.013
protein palmitoylationGO:0018345140.013
anatomical structure homeostasisGO:00602491450.013
positive regulation of gtpase activityGO:0043547850.013
Human
negative regulation of phosphate metabolic processGO:00459361840.013
transmission of nerve impulseGO:0019226760.013
engulfment of apoptotic cellGO:004365230.013
negative regulation of cellular amine metabolic processGO:003323910.013
response to growth factorGO:00708481980.013
rap protein signal transductionGO:003248630.013
fatty acid metabolic processGO:00066311210.013
modification dependent protein catabolic processGO:00199411330.013
regulation of cell adhesionGO:00301551540.013
chromatin modificationGO:00165681870.013
t cell differentiationGO:00302171740.013
stem cell differentiationGO:00488632680.013
exocytosisGO:00068871210.013
cell divisionGO:00513011200.013
hexose metabolic processGO:0019318980.013
peptide secretionGO:00027901140.013
regulation of protein serine threonine kinase activityGO:00719001570.012
urogenital system developmentGO:00016552610.012
epithelial cell developmentGO:00020641590.012
positive regulation of apoptotic processGO:00430652170.012
gonad developmentGO:00084061410.012
metal ion homeostasisGO:00550651890.012
epithelial tube morphogenesisGO:00605623030.012
regulation of metal ion transportGO:00109591060.012
cellular metal ion homeostasisGO:00068751510.012
lateral inhibitionGO:004633110.012
regulation of homeostatic processGO:00328441820.012
regulation of gtp catabolic processGO:00331241130.012
Human
calcium ion homeostasisGO:00550741270.012
inflammatory responseGO:00069542440.012
regulation of cytokine productionGO:00018172660.012
response to molecule of bacterial originGO:00022371430.012
regulation of ion transmembrane transportGO:00347651190.012
angiogenesisGO:00015252010.012
protein localization to membraneGO:00726571080.012
neuronal action potentialGO:0019228540.012
heart morphogenesisGO:00030071780.012
negative regulation of cell activationGO:00508661110.012
glial cell differentiationGO:00100011310.012
divalent metal ion transportGO:00708381720.012
positive regulation of purine nucleotide catabolic processGO:0033123880.012
Human
response to peptide hormoneGO:00434341270.012
regulation of establishment of protein localizationGO:00702011810.012
circulatory system processGO:00030131970.012
nucleocytoplasmic transportGO:00069131390.012
modification dependent macromolecule catabolic processGO:00436321330.012
dna repairGO:00062811070.012
regulation of protein catabolic processGO:00421761080.012
canonical wnt signaling pathwayGO:00600701300.012
spermatid differentiationGO:00485151150.012
cellular ion homeostasisGO:00068731650.012
proteolysis involved in cellular protein catabolic processGO:00516031470.012
cellular response to cytokine stimulusGO:00713451890.012
regulation of transmembrane transportGO:00347621280.011
myeloid leukocyte differentiationGO:00025731190.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
regulation of cell growthGO:0001558910.011
spermatid developmentGO:00072861080.011
establishment of organelle localizationGO:00516561220.011
regulation of response to woundingGO:19030341890.011
mitotic cell cycle processGO:19030471590.011
multicellular organism growthGO:00352641610.011
negative regulation of transferase activityGO:0051348850.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
renal system developmentGO:00720012250.011
positive regulation of neuron differentiationGO:00456661410.011
response to lipopolysaccharideGO:00324961280.011
cellular protein complex assemblyGO:00436231160.011
glucose metabolic processGO:0006006920.011
regulation of protein transportGO:00512231630.011
b cell activationGO:00421131610.011
regulation of cell sizeGO:0008361720.011
regulation of system processGO:00440572000.011
negative regulation of nervous system developmentGO:00519611560.011
positive regulation of programmed cell deathGO:00430682180.011
response to insulinGO:00328681000.011
regulation of leukocyte differentiationGO:19021051590.011
alcohol metabolic processGO:00060661160.011
action potentialGO:0001508780.011
inter male aggressive behaviorGO:000212130.011
regulation of ras gtpase activityGO:0032318880.011
Human
regulation of endopeptidase activityGO:0052548890.011
monosaccharide metabolic processGO:00059961060.011
organelle assemblyGO:00709251770.011
axon guidanceGO:00074111410.011
regulation of epithelial cell proliferationGO:00506781410.011
single fertilizationGO:0007338820.011
regulation of protein maturationGO:1903317960.011
regulation of cytoplasmic transportGO:19036491120.011
mitochondrion organizationGO:00070051340.011
positive regulation of gtp catabolic processGO:0033126850.011
Human
positive regulation of ras gtpase activityGO:0032320650.011
Human
glycerophospholipid metabolic processGO:0006650710.011
negative regulation of protein processingGO:0010955790.011
developmental cell growthGO:0048588840.010
response to oxygen levelsGO:0070482620.010
regulation of mitotic cell cycleGO:00073461260.010
regulation of actin filament based processGO:0032970990.010
meiotic nuclear divisionGO:00071261150.010
response to nutrient levelsGO:00316671090.010
negative regulation of synapse assemblyGO:005196430.010
regulation of peptidase activityGO:0052547960.010
development of primary sexual characteristicsGO:00451371430.010
carboxylic acid biosynthetic processGO:0046394860.010
negative regulation of immune system processGO:00026832090.010
methylationGO:00322591340.010
organic anion transportGO:00157111370.010
organic acid biosynthetic processGO:0016053860.010
epithelial cell proliferationGO:00506731740.010
oocyte axis specificationGO:000730920.010
intrinsic apoptotic signaling pathwayGO:00971931320.010
dendrite developmentGO:00163581150.010
nucleoside phosphate biosynthetic processGO:1901293790.010
ear developmentGO:00435832000.010
multi multicellular organism processGO:00447061090.010
positive regulation of cell projection organizationGO:0031346950.010
tissue homeostasisGO:00018941150.010
cellular divalent inorganic cation homeostasisGO:00725031270.010
striated muscle cell developmentGO:00550021250.010
positive regulation of nucleotide catabolic processGO:0030813880.010
Human
neuron deathGO:00709971540.010
proteasomal protein catabolic processGO:0010498980.010
calcium ion transmembrane transportGO:0070588850.010
cellular component assembly involved in morphogenesisGO:00109271390.010
cell maturationGO:00484691270.010
positive regulation of cell activationGO:00508671580.010

Arhgef4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.037
disease of anatomical entityDOID:700.037
disease of cellular proliferationDOID:1456600.013
central nervous system diseaseDOID:33100.013
cancerDOID:16200.013
organ system cancerDOID:005068600.013
disease of metabolismDOID:001466700.012
inherited metabolic disorderDOID:65500.012