Mus musculus

158 known processes

Traf2

TNF receptor-associated factor 2

(Aliases: AI325259)

Traf2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ripoptosome assembly involved in necroptotic processGO:190102660.997
programmed necrotic cell deathGO:0097300280.991
regulation of necroptotic processGO:0060544100.978
negative regulation of necroptotic processGO:006054690.976
regulation of interleukin 10 secretionGO:200117940.967
interleukin 10 secretionGO:007260840.951
negative regulation of necrotic cell deathGO:0060547110.933
necroptotic processGO:0070266210.928
interleukin 5 secretionGO:007260320.928
germinal center formationGO:0002467160.917
negative regulation of ripoptosome assembly involved in necroptotic processGO:190244330.882
extrinsic apoptotic signaling pathwayGO:00971911260.867
Human
immune response activating signal transductionGO:00027571160.853
Mouse
necrotic cell deathGO:0070265300.851
adaptive immune responseGO:00022501550.816
Human Mouse
negative regulation of interleukin 10 secretionGO:200118020.760
immunoglobulin productionGO:0002377730.752
regulation of interleukin 13 secretionGO:200066520.746
regulation of interleukin 5 secretionGO:200066220.742
positive regulation of jnk cascadeGO:0046330460.737
Human
lymphocyte proliferationGO:00466511640.690
Mouse
regulation of defense responseGO:00313472330.678
Mouse
i kappab kinase nf kappab signalingGO:0007249850.649
Mouse
defense response to other organismGO:00985421970.631
Mouse
regulation of necrotic cell deathGO:0010939130.617
response to molecule of bacterial originGO:00022371430.594
Mouse
lymphocyte apoptotic processGO:0070227540.548
regulation of stress activated mapk cascadeGO:0032872690.543
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.543
Human
stress activated protein kinase signaling cascadeGO:0031098810.531
positive regulation of lymphocyte activationGO:00512511400.507
Mouse
regulation of t cell proliferationGO:0042129920.504
Mouse
activation of immune responseGO:00022531380.502
Mouse
myeloid cell differentiationGO:00300992330.501
Mouse
positive regulation of protein modification processGO:00314012990.501
Human
positive regulation of programmed cell deathGO:00430682180.500
Human
jnk cascadeGO:0007254720.498
regulation of cellular response to stressGO:00801351590.493
positive regulation of defense responseGO:00313491240.493
Mouse
positive regulation of fever generation by positive regulation of prostaglandin secretionGO:007181220.484
positive regulation of leukocyte proliferationGO:0070665730.473
Mouse
apoptotic signaling pathwayGO:00971903060.468
Human
negative regulation of interleukin 5 secretionGO:200066310.468
regulation of leukocyte proliferationGO:00706631210.466
Mouse
somatic recombination of immunoglobulin gene segmentsGO:0016447420.461
activation of innate immune responseGO:0002218560.459
Mouse
dna metabolic processGO:00062593030.454
negative regulation of interleukin 13 productionGO:003269620.441
defense response to bacteriumGO:00427421190.439
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.435
Human Mouse
negative regulation of interleukin 13 secretionGO:200066610.433
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753100.428
negative regulation of lymphocyte activationGO:0051250910.427
toll like receptor signaling pathwayGO:0002224380.422
Mouse
protein polyubiquitinationGO:0000209330.411
Human Mouse
cell type specific apoptotic processGO:00972852680.401
myd88 independent toll like receptor signaling pathwayGO:000275630.388
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.383
response to tumor necrosis factorGO:0034612260.356
Human Mouse
regulation of cd8 positive alpha beta cytotoxic t cell extravasationGO:200045220.349
regulation of cytokine secretion involved in immune responseGO:000273940.346
cellular response to lipopolysaccharideGO:0071222770.335
Mouse
myeloid dendritic cell differentiationGO:0043011160.334
Mouse
peptidyl amino acid modificationGO:00181933360.331
lymphocyte differentiationGO:00300982420.314
regulation of mapk cascadeGO:00434082480.308
neuron apoptotic processGO:00514021420.306
nucleotide binding oligomerization domain containing signaling pathwayGO:007042360.305
mapk cascadeGO:00001652810.300
circadian temperature homeostasisGO:006008620.299
b cell activationGO:00421131610.298
intrinsic apoptotic signaling pathwayGO:00971931320.293
protein modification by small protein conjugationGO:00324461870.292
Human Mouse
glial cell apoptotic processGO:003434930.290
leukocyte proliferationGO:00706611720.289
Mouse
regulation of apoptotic signaling pathwayGO:20012331970.288
Human
negative regulation of inflammatory responseGO:0050728610.277
regulation of anion transportGO:0044070270.277
cellular response to biotic stimulusGO:0071216920.277
Mouse
regulation of response to biotic stimulusGO:0002831380.273
Mouse
regulation of immunoglobulin secretionGO:0051023120.273
regulation of b cell activationGO:0050864810.270
regulation of transferase activityGO:00513382630.266
Human
cellular response to molecule of bacterial originGO:0071219830.261
Mouse
homeostasis of number of cellsGO:00488722100.260
interleukin 13 secretionGO:007261120.253
regulation of hepatocyte proliferationGO:200034560.252
regulation of cell activationGO:00508652890.251
Mouse
neuron deathGO:00709971540.249
regulation of t cell activationGO:00508631700.248
Mouse
leukocyte differentiationGO:00025213420.247
Mouse
nik nf kappab signalingGO:0038061140.246
Human
negative regulation of apoptotic signaling pathwayGO:20012341040.241
regulation of interleukin 2 productionGO:0032663280.238
Human
establishment of protein localization to organelleGO:00725941180.235
innate immune response activating signal transductionGO:0002758500.232
Mouse
negative regulation of defense responseGO:0031348770.229
positive regulation of cytokine biosynthetic processGO:0042108400.229
Mouse
b cell apoptotic processGO:0001783190.227
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.226
Mouse
regulation of lymphocyte mediated immunityGO:0002706840.225
Human
positive regulation of lymphocyte proliferationGO:0050671700.223
Mouse
t cell proliferationGO:00420981200.220
Mouse
regulation of lymphocyte proliferationGO:00506701170.217
Mouse
immunoglobulin secretionGO:0048305170.214
protein modification by small protein conjugation or removalGO:00706472070.210
Human Mouse
nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042750.207
lymphocyte mediated immunityGO:00024491390.206
Human
tumor necrosis factor mediated signaling pathwayGO:0033209130.204
Human Mouse
immune effector processGO:00022523210.204
regulation of reactive oxygen species metabolic processGO:2000377400.195
protein secretionGO:00093061110.195
pattern recognition receptor signaling pathwayGO:0002221470.186
Mouse
cd4 positive alpha beta t cell differentiationGO:0043367410.183
positive regulation of lymphocyte mediated immunityGO:0002708620.183
Human
regulation of cysteine type endopeptidase activityGO:2000116650.181
positive regulation of cell activationGO:00508671580.181
Mouse
positive regulation of cell deathGO:00109422240.181
Human
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.180
cellular response to tumor necrosis factorGO:0071356210.180
Human Mouse
positive regulation of interleukin 12 productionGO:0032735210.175
Mouse
negative regulation of odontogenesis of dentin containing toothGO:004248910.172
ripoptosome assemblyGO:009734360.172
leukocyte apoptotic processGO:0071887710.166
regulation of cellular amino acid metabolic processGO:000652150.165
positive regulation of apoptotic signaling pathwayGO:2001235950.165
Human
negative regulation of odontogenesisGO:004248330.163
cytokine mediated signaling pathwayGO:00192211150.162
Human Mouse
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.161
negative regulation of interleukin 5 productionGO:003271440.157
antigen receptor mediated signaling pathwayGO:0050851640.157
positive regulation of production of molecular mediator of immune responseGO:0002702450.157
Human
immune response regulating signaling pathwayGO:00027641250.156
Mouse
macromolecule catabolic processGO:00090572810.155
regulation of innate immune responseGO:0045088910.150
Mouse
negative regulation of phosphorus metabolic processGO:00105631840.149
cellular response to lipidGO:00713961450.149
Mouse
regulation of cytokine productionGO:00018172660.147
Human Mouse
regulation of b cell proliferationGO:0030888390.146
chromatin organizationGO:00063252060.145
regulation of protein maturationGO:1903317960.144
stress activated mapk cascadeGO:0051403800.144
anion transportGO:00068201770.144
regulation of protein complex assemblyGO:0043254830.143
t helper cell differentiationGO:0042093280.141
myeloid dendritic cell activationGO:0001773250.136
Mouse
regulation of leukocyte mediated immunityGO:00027031040.136
Human
positive regulation of b cell activationGO:0050871490.135
regulation of endothelial cell apoptotic processGO:200035190.134
cytokine productionGO:00018163190.134
Human Mouse
positive regulation of apoptotic processGO:00430652170.133
Human
negative regulation of protein processingGO:0010955790.131
myeloid leukocyte differentiationGO:00025731190.130
Mouse
peptidyl serine modificationGO:0018209830.129
positive regulation of response to cytokine stimulusGO:0060760110.122
defense response to gram positive bacteriumGO:0050830500.122
regulation of inflammatory responseGO:00507271470.121
regulation of germinal center formationGO:0002634100.120
positive regulation of immature t cell proliferationGO:003309140.120
regulation of alpha beta t cell activationGO:0046634530.118
protein ubiquitinationGO:00165671710.118
Human Mouse
protein targetingGO:00066051430.117
regulation of organelle organizationGO:00330432890.117
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.116
positive regulation of cellular protein catabolic processGO:1903364340.115
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.115
spleen developmentGO:0048536390.115
positive regulation of cytokine secretion involved in immune responseGO:000274120.115
cellular protein catabolic processGO:00442571550.114
b cell activation involved in immune responseGO:0002312500.113
protein processingGO:00164851630.113
regulation of alpha beta t cell proliferationGO:0046640180.109
immune response regulating cell surface receptor signaling pathwayGO:0002768800.108
interleukin 6 productionGO:0032635580.107
Mouse
nucleocytoplasmic transportGO:00069131390.106
negative regulation of intracellular signal transductionGO:19025321670.106
regulation of organ morphogenesisGO:20000271440.106
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.106
Human
positive regulation of t helper 1 cell differentiationGO:004562740.105
negative regulation of t cell activationGO:0050868650.105
negative regulation of hydrolase activityGO:0051346710.104
necroptotic signaling pathwayGO:009752730.104
negative regulation of b cell activationGO:0050869270.102
negative regulation of lipopolysaccharide mediated signaling pathwayGO:003166530.102
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043160.102
alpha beta t cell differentiation involved in immune responseGO:0002293300.102
cellular amino acid metabolic processGO:00065201030.101
negative regulation of cell proliferationGO:00082852960.101
regulation of interleukin 6 productionGO:0032675550.100
Mouse
negative regulation of molecular functionGO:00440922580.098
Mouse
positive regulation of kinase activityGO:00336741550.098
Human
response to interleukin 12GO:007067120.097
regulation of alpha beta t cell differentiationGO:0046637350.095
regulation of ion transportGO:00432692150.094
positive regulation of b cell proliferationGO:0030890240.092
somatic cell dna recombinationGO:0016444510.091
lymph node developmentGO:0048535180.091
regulation of protein localizationGO:00328802310.091
positive regulation of innate immune responseGO:0045089800.091
Mouse
cellular ketone metabolic processGO:0042180840.091
leukocyte homeostasisGO:0001776790.091
negative regulation of proteolysisGO:0045861740.090
cellular response to dna damage stimulusGO:00069742070.089
alpha beta t cell activationGO:0046631910.089
interleukin 8 productionGO:003263740.087
immunoglobulin mediated immune responseGO:0016064690.087
type i interferon productionGO:0032606290.086
Mouse
cytokine secretion involved in immune responseGO:000237460.085
regulation of ripoptosome assembly involved in necroptotic processGO:190244230.084
protein maturationGO:00516041760.084
regulation of cytokine biosynthetic processGO:0042035590.084
Mouse
b cell proliferationGO:0042100530.084
inflammatory responseGO:00069542440.083
positive regulation of transferase activityGO:00513471670.082
Human
dna recombinationGO:0006310920.082
circadian rhythmGO:00076231140.080
somatic diversification of immunoglobulinsGO:0016445430.079
regulation of defense response to virusGO:0050688180.079
Mouse
cellular response to nitric oxideGO:007173240.079
regulation of response to woundingGO:19030341890.079
protein import into nucleusGO:0006606950.078
chromatin modificationGO:00165681870.078
response to nitric oxideGO:007173140.077
response to reactive oxygen speciesGO:0000302560.076
negative regulation of multi organism processGO:0043901680.075
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.075
dendritic cell differentiationGO:0097028260.073
Mouse
positive regulation of cytokine productionGO:00018191740.073
Human Mouse
histone modificationGO:00165701590.071
regulation of proteolysisGO:00301621640.071
Mouse
negative regulation of cell activationGO:00508661110.069
intracellular protein transportGO:00068862040.069
negative regulation of immune system processGO:00026832090.068
regulation of establishment of protein localizationGO:00702011810.067
regulation of multi organism processGO:00439001110.066
Mouse
positive regulation of cellular amine metabolic processGO:003324050.065
positive regulation of immune effector processGO:00026991070.064
Human
positive regulation of cellular amino acid metabolic processGO:004576430.064
regulation of interleukin 8 productionGO:003267730.063
endothelial cell apoptotic processGO:007257790.063
t cell apoptotic processGO:0070231390.062
alpha beta t cell proliferationGO:0046633210.062
cellular protein complex assemblyGO:00436231160.061
regulation of peptidase activityGO:0052547960.061
production of molecular mediator of immune responseGO:00024401030.061
positive regulation of inflammatory responseGO:0050729470.061
negative regulation of protein transportGO:0051224460.060
positive regulation of type i interferon mediated signaling pathwayGO:006034040.060
cellular response to estrogen stimulusGO:0071391120.060
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.059
b 1 b cell homeostasisGO:000192240.059
innate immune responseGO:00450871570.059
Mouse
regulation of protein targetingGO:1903533610.057
positive regulation of mapk cascadeGO:00434101700.057
Human
protein localization to organelleGO:00333651850.057
covalent chromatin modificationGO:00165691630.057
negative regulation of cellular protein metabolic processGO:00322692470.057
negative regulation of alpha beta t cell proliferationGO:004664250.056
regulation of lymphocyte apoptotic processGO:0070228410.056
regulation of kinase activityGO:00435492490.056
Human
posttranscriptional regulation of gene expressionGO:00106081550.056
positive regulation of interleukin 8 productionGO:003275720.055
t cell receptor signaling pathwayGO:0050852460.055
negative regulation of cysteine type endopeptidase activityGO:2000117220.055
negative regulation of cytokine productionGO:0001818840.055
regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042830.055
positive regulation of protein kinase activityGO:00458601440.055
Human
lymphocyte activation involved in immune responseGO:0002285930.054
amine metabolic processGO:0009308450.053
protein methylationGO:0006479810.053
isotype switchingGO:0045190360.053
regulation of cytoplasmic transportGO:19036491120.053
response to lipopolysaccharideGO:00324961280.052
Mouse
regulation of jnk cascadeGO:0046328620.052
regulation of hydrolase activityGO:00513362460.052
organic anion transportGO:00157111370.052
rhythmic processGO:00485111740.051
proteolysis involved in cellular protein catabolic processGO:00516031470.051
regulation of adaptive immune responseGO:0002819900.050
Human
regulation of protein processingGO:0070613960.049
cellular response to growth factor stimulusGO:00713631970.049
interleukin 10 productionGO:0032613230.048
cellular response to cytokine stimulusGO:00713451890.048
Human Mouse
fatty acid derivative transportGO:1901571140.048
regulation of secretionGO:00510462740.048
cellular response to oxidative stressGO:0034599760.048
cd8 positive alpha beta cytotoxic t cell extravasationGO:003569820.047
regulation of protein ubiquitinationGO:0031396520.047
positive regulation of antimicrobial peptide productionGO:000222510.047
regulation of cytokine production involved in immune responseGO:0002718260.047
Human
t cell differentiationGO:00302171740.046
symbiosis encompassing mutualism through parasitismGO:0044403830.046
regulation of intracellular transportGO:00323861590.045
t cell activationGO:00421102890.045
Mouse
leukocyte activation involved in immune responseGO:00023661260.045
ossificationGO:00015032160.045
Mouse
regulation of protein modification by small protein conjugation or removalGO:1903320570.045
negative regulation of protein maturationGO:1903318790.044
toll like receptor 3 signaling pathwayGO:003413840.044
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.044
Human
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.044
negative regulation of alpha beta t cell activationGO:0046636180.044
cd4 positive alpha beta t cell lineage commitmentGO:004337360.044
regulation of purine nucleotide catabolic processGO:00331211220.043
positive regulation of stress activated mapk cascadeGO:0032874480.043
Human
negative regulation of response to woundingGO:1903035770.043
lymphocyte homeostasisGO:0002260640.043
negative regulation of endopeptidase activityGO:0010951440.043
response to oxidative stressGO:00069791230.042
nitrogen compound transportGO:00717052710.042
regulation of protein serine threonine kinase activityGO:00719001570.041
Human
negative regulation of protein metabolic processGO:00512482820.040
modification dependent protein catabolic processGO:00199411330.040
negative regulation of lymphocyte proliferationGO:0050672450.040
tissue remodelingGO:00487711020.039
Mouse
peptidyl serine autophosphorylationGO:003628910.039
protein catabolic processGO:00301632210.039
extracellular structure organizationGO:00430621480.039
negative regulation of protein modification processGO:00314001630.039
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.039
cell activation involved in immune responseGO:00022631260.039
defense response to virusGO:0051607680.039
Mouse
negative regulation of reactive oxygen species metabolic processGO:2000378100.038
positive regulation of protein catabolic processGO:0045732600.038
positive regulation of protein serine threonine kinase activityGO:00719021060.038
Human
nucleic acid phosphodiester bond hydrolysisGO:0090305490.038
regulation of cellular component biogenesisGO:00440871810.038
regulation of t cell apoptotic processGO:0070232280.037
detection of bacteriumGO:001604570.037
protein homooligomerizationGO:0051260430.037
Human
gland developmentGO:00487323300.037
activation of nf kappab inducing kinase activityGO:000725040.037
Human
regulation of b cell mediated immunityGO:0002712370.037
cellular macromolecule catabolic processGO:00442652060.037
aromatic compound catabolic processGO:00194392860.036
regulation of lymphocyte activationGO:00512492400.036
Mouse
cellular amine metabolic processGO:0044106440.035
positive regulation of homeostatic processGO:0032846640.035
epithelial cell proliferationGO:00506731740.035
regulation of sequence specific dna binding transcription factor activityGO:00510901060.035
regulation of rna stabilityGO:0043487260.035
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.035
negative regulation of b cell proliferationGO:0030889130.034
regulation of cell cycleGO:00517262810.034
mitochondrion organizationGO:00070051340.034
hepaticobiliary system developmentGO:0061008670.034
regulation of nucleotide binding oligomerization domain containing signaling pathwayGO:007042430.034
negative regulation of toll like receptor signaling pathwayGO:0034122140.033
cellular response to abiotic stimulusGO:0071214560.033
regulation of myd88 independent toll like receptor signaling pathwayGO:003412710.033
leukocyte mediated immunityGO:00024431740.033
Human
negative regulation of nf kappab transcription factor activityGO:0032088150.033
Mouse
oligodendrocyte apoptotic processGO:009725210.033
negative regulation of phosphate metabolic processGO:00459361840.033
placenta developmentGO:00018901400.033
nuclear transportGO:00511691390.033
regulation of mitotic cell cycleGO:00073461260.032
cdc42 protein signal transductionGO:003248800.032
carboxylic acid transportGO:00469421000.032
response to organic cyclic compoundGO:00140701980.032
regulation of protein catabolic processGO:00421761080.032
regulation of cd8 positive alpha beta t cell proliferationGO:200056410.031
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.031
negative regulation of phosphorylationGO:00423261660.031
somatic diversification of immune receptorsGO:0002200530.031
cytoplasmic transportGO:00164822340.031
b cell mediated immunityGO:0019724710.031
regulation of dna recombinationGO:0000018340.031
activation induced cell death of t cellsGO:0006924100.030
response to transforming growth factor betaGO:0071559880.030
liver developmentGO:0001889660.030
immune response activating cell surface receptor signaling pathwayGO:0002429720.030
lipid transportGO:0006869980.029
multicellular organismal homeostasisGO:00488711640.029
Mouse
regulation of isotype switchingGO:0045191220.029
t cell lineage commitmentGO:0002360130.029
regulation of cellular catabolic processGO:00313292420.029
regulation of endopeptidase activityGO:0052548890.029
negative regulation of protein secretionGO:0050709200.029
carbohydrate derivative catabolic processGO:19011362310.029
establishment of protein localization to vacuoleGO:007266640.029
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.028
regulation of lipid transportGO:0032368360.028
antimicrobial peptide productionGO:000277520.028
regulation of nucleocytoplasmic transportGO:0046822730.028
detection of external biotic stimulusGO:009858190.028
positive regulation of erk1 and erk2 cascadeGO:0070374470.028
tyrosine phosphorylation of stat1 proteinGO:004250830.028
lipopolysaccharide mediated signaling pathwayGO:0031663250.028
Mouse
regulation of cellular protein catabolic processGO:1903362610.027
metal ion homeostasisGO:00550651890.027
positive regulation of leukocyte mediated immunityGO:0002705700.027
Human
purine ribonucleoside metabolic processGO:00461282410.027
thymus developmentGO:0048538410.027
regulation of protein deacetylationGO:0090311170.027
interleukin 12 biosynthetic processGO:004209080.027
Mouse
cellular homeostasisGO:00197252400.027
positive regulation of protein secretionGO:0050714520.027
modification dependent macromolecule catabolic processGO:00436321330.027
response to peptideGO:19016521360.027
mammary gland lobule developmentGO:0061377220.027
b cell homeostasisGO:0001782340.027
fatty acid transportGO:0015908280.027
regulation of intracellular protein transportGO:0033157820.027
nucleobase containing small molecule metabolic processGO:00550863520.027
purine nucleoside triphosphate catabolic processGO:00091462030.027
icosanoid transportGO:0071715140.026
liver morphogenesisGO:007257680.026
regulation of chromosome organizationGO:0033044830.026
regulation of bindingGO:00510981110.026
Human
inhibition of cysteine type endopeptidase activity involved in apoptotic processGO:199000110.026
reactive oxygen species metabolic processGO:0072593840.026
positive regulation of myeloid cell differentiationGO:0045639430.026
regulation of antibacterial peptide biosynthetic processGO:000280810.026
positive regulation of organelle organizationGO:00106381280.026
regulation of cellular ketone metabolic processGO:0010565660.026
osteoclast differentiationGO:0030316620.026
Mouse
regulation of toll like receptor signaling pathwayGO:0034121200.025
regulation of icosanoid secretionGO:003230380.025
regulation of growth of symbiont in hostGO:0044126190.025
regulation of heat generationGO:003165080.025
positive regulation of lipid transportGO:0032370220.025
response to inorganic substanceGO:0010035960.025
extracellular matrix organizationGO:00301981470.025
purine nucleotide catabolic processGO:00061952110.024
cellular nitrogen compound catabolic processGO:00442702800.024
positive regulation of fatty acid transportGO:200019380.024
positive regulation of isotype switchingGO:0045830150.024
cd8 positive alpha beta t cell proliferationGO:003574010.024
response to muramyl dipeptideGO:003249590.024
ras protein signal transductionGO:0007265770.024
ubiquitin dependent protein catabolic processGO:00065111290.024
t cell selectionGO:0045058340.024
prostaglandin transportGO:001573270.023
acid secretionGO:0046717330.023
camera type eye developmentGO:00430102660.023
dna repairGO:00062811070.023
hematopoietic progenitor cell differentiationGO:00022441430.023
regulation of type i interferon productionGO:0032479220.023
Mouse
negative regulation of endothelial cell apoptotic processGO:200035270.023
negative regulation of interferon beta productionGO:003268830.023
regulation of map kinase activityGO:00434051200.023
Human
tube formationGO:00351481400.022
Mouse
peptidyl serine phosphorylationGO:0018105740.022
heat generationGO:0031649130.022
sensory organ morphogenesisGO:00905962420.022
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.022
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.022
Human
interspecies interaction between organismsGO:0044419830.022
regulation of immunoglobulin productionGO:0002637420.022
negative regulation of cellular component organizationGO:00511291940.022
positive regulation of icosanoid secretionGO:003230570.022
growth of symbiont in hostGO:0044117230.022
regulation of defense response to virus by hostGO:005069180.022
t helper 17 cell lineage commitmentGO:007254040.022
positive regulation of transcription factor import into nucleusGO:004299380.022
epithelial tube formationGO:00721751300.022
Mouse
regulation of nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043230.022
positive regulation of interleukin 12 biosynthetic processGO:004508460.022
Mouse
response to interleukin 1GO:0070555110.021
Mouse
regulation of odontogenesis of dentin containing toothGO:0042487110.021
t cell mediated immunityGO:0002456500.021
Human
alpha beta t cell lineage commitmentGO:000236370.021
icosanoid secretionGO:0032309120.021
lymphocyte migrationGO:0072676260.021
regulation of odontogenesisGO:0042481180.021
nucleobase containing compound transportGO:0015931270.021
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.021
lipid localizationGO:00108761260.020
chemokine productionGO:0032602340.020
monocarboxylic acid transportGO:0015718440.020
response to dsrnaGO:0043331300.020
negative regulation of cytokine secretionGO:0050710150.020
regulation of fever generation by regulation of prostaglandin secretionGO:007181020.020
humoral immune responseGO:0006959570.020
ion transmembrane transportGO:00342203610.020
positive regulation of b cell mediated immunityGO:0002714260.020
regulation of ligase activityGO:0051340100.020
glucose homeostasisGO:00425931280.020
negative regulation of kinase activityGO:0033673810.020
fever generationGO:000166070.020
positive regulation of intracellular transportGO:0032388700.019
t helper 2 cell cytokine productionGO:003574540.019
positive regulation of antimicrobial humoral responseGO:000276020.019
negative regulation of transferase activityGO:0051348850.019
positive regulation of t cell cytokine productionGO:000272650.019
Human
positive regulation of organic acid transportGO:0032892110.019
positive regulation of protein localization to nucleusGO:1900182300.019
negative regulation of protein phosphorylationGO:00019331260.019

Traf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.025
disease of anatomical entityDOID:700.025
hematopoietic system diseaseDOID:7400.025
disease of cellular proliferationDOID:1456600.024
osteosclerosisDOID:425400.021
bone remodeling diseaseDOID:008000500.021
bone diseaseDOID:008000100.021
osteopetrosisDOID:1353300.021
musculoskeletal system diseaseDOID:1700.021
connective tissue diseaseDOID:6500.021