IMP: Integrative Multi-species Prediction

Mus musculus

13 known processes

Traf4

TNF receptor associated factor 4

(Aliases: CART1,msp2,A530032M13Rik)

Ensembl: ENSMUSG00000017386
Entrez: 22032
UniProtKB: Q61382

Process Predictions
Disease Predictions

Traf4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cellular amine metabolic process	GO:0044106	44	0.235
cellular amino acid metabolic process	GO:0006520	103	0.231
regulation of cellular ketone metabolic process	GO:0010565	66	0.213
leukocyte differentiation	GO:0002521	342	0.209	Mouse
cellular ketone metabolic process	GO:0042180	84	0.172
amine metabolic process	GO:0009308	45	0.158
regulation of cellular amine metabolic process	GO:0033238	20	0.142
peptidyl amino acid modification	GO:0018193	336	0.135
regulation of cellular amino acid metabolic process	GO:0006521	5	0.120
regulation of defense response	GO:0031347	233	0.109	Mouse
regulation of kinase activity	GO:0043549	249	0.107	Human
leukocyte proliferation	GO:0070661	172	0.105	Mouse
regulation of protein kinase activity	GO:0045859	232	0.102	Human
t cell activation	GO:0042110	289	0.099	Mouse
neural tube closure	GO:0001843	90	0.098	Mouse
regulation of apoptotic signaling pathway	GO:2001233	197	0.093
ras protein signal transduction	GO:0007265	77	0.092
camera type eye development	GO:0043010	266	0.091
positive regulation of cell death	GO:0010942	224	0.091	Fly
neural tube development	GO:0021915	160	0.090	Mouse
immune effector process	GO:0002252	321	0.090	Mouse
forebrain development	GO:0030900	302	0.089
positive regulation of cellular amine metabolic process	GO:0033240	5	0.086
actin cytoskeleton organization	GO:0030036	220	0.085
regulation of mapk cascade	GO:0043408	248	0.084	Human Mouse Fly
skeletal system development	GO:0001501	356	0.083
apoptotic signaling pathway	GO:0097190	306	0.082
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.082
positive regulation of programmed cell death	GO:0043068	218	0.080	Fly
negative regulation of cell development	GO:0010721	169	0.079
positive regulation of protein phosphorylation	GO:0001934	242	0.076	Human
urogenital system development	GO:0001655	261	0.072
spermatogenesis	GO:0007283	284	0.070
regulation of transferase activity	GO:0051338	263	0.070	Human
embryonic organ morphogenesis	GO:0048562	276	0.069
insulin secretion	GO:0030073	89	0.068
limb development	GO:0060173	166	0.066
regulation of cellular response to stress	GO:0080135	159	0.065	Human Mouse Fly
negative regulation of cellular protein metabolic process	GO:0032269	247	0.065
dna metabolic process	GO:0006259	303	0.064
morphogenesis of a branching epithelium	GO:0061138	193	0.064
developmental maturation	GO:0021700	193	0.064
cell adhesion	GO:0007155	329	0.064
regulation of homeostatic process	GO:0032844	182	0.064
epithelial tube morphogenesis	GO:0060562	303	0.063	Mouse
muscle tissue development	GO:0060537	308	0.063
nitrogen compound transport	GO:0071705	271	0.063
carbohydrate homeostasis	GO:0033500	128	0.062
skeletal system morphogenesis	GO:0048705	203	0.061
ossification	GO:0001503	216	0.061	Mouse
negative regulation of protein metabolic process	GO:0051248	282	0.061
transmembrane transport	GO:0055085	412	0.060
cellular homeostasis	GO:0019725	240	0.059
cytoplasmic transport	GO:0016482	234	0.058
regulation of membrane potential	GO:0042391	192	0.058
rho protein signal transduction	GO:0007266	32	0.058
muscle cell differentiation	GO:0042692	261	0.057
epithelial cell proliferation	GO:0050673	174	0.057
protein modification by small protein conjugation or removal	GO:0070647	207	0.056	Mouse
lipid biosynthetic process	GO:0008610	179	0.054
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.054
morphogenesis of a branching structure	GO:0001763	203	0.054
regulation of organelle organization	GO:0033043	289	0.053
regulation of hormone levels	GO:0010817	211	0.053
amide transport	GO:0042886	138	0.053
peptide transport	GO:0015833	133	0.052
protein ubiquitination	GO:0016567	171	0.052	Mouse
sensory perception	GO:0007600	245	0.051
nucleoside triphosphate catabolic process	GO:0009143	205	0.051
negative regulation of phosphate metabolic process	GO:0045936	184	0.051
oxidation reduction process	GO:0055114	342	0.050
rhythmic process	GO:0048511	174	0.050
stem cell differentiation	GO:0048863	268	0.049
regulation of cell activation	GO:0050865	289	0.048	Mouse
appendage development	GO:0048736	166	0.047
regionalization	GO:0003002	337	0.047
stem cell proliferation	GO:0072089	117	0.046
stem cell development	GO:0048864	219	0.046
gland development	GO:0048732	330	0.046	Fly
negative regulation of phosphorylation	GO:0042326	166	0.046
regulation of protein serine threonine kinase activity	GO:0071900	157	0.045
cellular lipid metabolic process	GO:0044255	323	0.044
peptide hormone secretion	GO:0030072	109	0.044
positive regulation of apoptotic process	GO:0043065	217	0.044	Fly
myeloid cell differentiation	GO:0030099	233	0.044	Mouse
macromolecule catabolic process	GO:0009057	281	0.044	Mouse
regulation of cellular component biogenesis	GO:0044087	181	0.044
organic cyclic compound catabolic process	GO:1901361	295	0.043
nucleobase containing small molecule metabolic process	GO:0055086	352	0.043
embryonic epithelial tube formation	GO:0001838	130	0.043	Mouse
cation transport	GO:0006812	399	0.043
morphogenesis of embryonic epithelium	GO:0016331	159	0.043	Mouse
cellular chemical homeostasis	GO:0055082	215	0.042
peptide secretion	GO:0002790	114	0.042
regulation of cytoskeleton organization	GO:0051493	122	0.042
regulation of neuron differentiation	GO:0045664	281	0.042
cellular response to hexose stimulus	GO:0071331	47	0.042
neuron projection guidance	GO:0097485	141	0.041
striated muscle tissue development	GO:0014706	293	0.041
digestive system development	GO:0055123	200	0.040	Fly
male gamete generation	GO:0048232	285	0.040
hormone secretion	GO:0046879	128	0.040
purine ribonucleoside catabolic process	GO:0046130	205	0.040
response to monosaccharide	GO:0034284	67	0.040
lymphocyte differentiation	GO:0030098	242	0.039
regulation of secretion by cell	GO:1903530	249	0.039	Mouse
regulation of secretion	GO:0051046	274	0.039	Mouse
regulation of cell migration	GO:0030334	219	0.039
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.039
cation homeostasis	GO:0055080	212	0.039
negative regulation of protein modification process	GO:0031400	163	0.039
t cell differentiation	GO:0030217	174	0.039
negative regulation of protein phosphorylation	GO:0001933	126	0.038
alpha beta t cell differentiation	GO:0046632	69	0.038
regulation of organ morphogenesis	GO:2000027	144	0.038
positive regulation of protein modification process	GO:0031401	299	0.038	Human
lymphocyte proliferation	GO:0046651	164	0.038	Mouse
regulation of multi organism process	GO:0043900	111	0.038	Mouse
heterocycle catabolic process	GO:0046700	280	0.037
labyrinthine layer development	GO:0060711	49	0.037
neural tube formation	GO:0001841	108	0.037	Mouse
negative regulation of nervous system development	GO:0051961	156	0.037
small gtpase mediated signal transduction	GO:0007264	97	0.037
sensory organ morphogenesis	GO:0090596	242	0.037
regulation of intracellular transport	GO:0032386	159	0.037
homeostasis of number of cells	GO:0048872	210	0.037
heart morphogenesis	GO:0003007	178	0.037
regulation of translation	GO:0006417	71	0.037
carbohydrate metabolic process	GO:0005975	230	0.036
intrinsic apoptotic signaling pathway	GO:0097193	132	0.036
appendage morphogenesis	GO:0035107	149	0.036
axon ensheathment	GO:0008366	76	0.036
glucose homeostasis	GO:0042593	128	0.036
regulation of peptide secretion	GO:0002791	77	0.036
regulation of cellular catabolic process	GO:0031329	242	0.036
membrane organization	GO:0061024	245	0.036
posttranscriptional regulation of gene expression	GO:0010608	155	0.035
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.035
regulation of hydrolase activity	GO:0051336	246	0.035
myeloid cell homeostasis	GO:0002262	114	0.035
guanosine containing compound catabolic process	GO:1901069	144	0.035
cholesterol homeostasis	GO:0042632	44	0.035
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.035
purine nucleoside metabolic process	GO:0042278	241	0.035
primary neural tube formation	GO:0014020	95	0.035	Mouse
regulation of translational initiation	GO:0006446	15	0.035
gtp catabolic process	GO:0006184	143	0.034
positive regulation of kinase activity	GO:0033674	155	0.034	Human
hindbrain development	GO:0030902	128	0.034
negative regulation of neuron differentiation	GO:0045665	101	0.034
purine nucleotide catabolic process	GO:0006195	211	0.033
sterol homeostasis	GO:0055092	45	0.033
regulation of peptide hormone secretion	GO:0090276	75	0.033
oocyte construction	GO:0007308	2	0.033
chromatin modification	GO:0016568	187	0.033
tube formation	GO:0035148	140	0.033	Mouse
regulation of cell cycle	GO:0051726	281	0.033
positive regulation of cellular catabolic process	GO:0031331	148	0.032
regulation of lipid metabolic process	GO:0019216	118	0.032
cell type specific apoptotic process	GO:0097285	268	0.032
negative regulation of cell proliferation	GO:0008285	296	0.032
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.032
adaptive immune response	GO:0002250	155	0.031	Mouse
placenta development	GO:0001890	140	0.031
multicellular organismal homeostasis	GO:0048871	164	0.031	Mouse
organonitrogen compound catabolic process	GO:1901565	264	0.031
cartilage development	GO:0051216	140	0.031
pallium development	GO:0021543	120	0.031
regulation of peptide transport	GO:0090087	91	0.031
embryonic placenta development	GO:0001892	98	0.031
regulation of response to wounding	GO:1903034	189	0.031
digestive tract development	GO:0048565	190	0.030	Fly
translational initiation	GO:0006413	24	0.030
regulation of cell cycle process	GO:0010564	160	0.030
regulation of epithelial cell proliferation	GO:0050678	141	0.030
wnt signaling pathway	GO:0016055	188	0.030
lipid homeostasis	GO:0055088	63	0.030
negative regulation of molecular function	GO:0044092	258	0.030	Mouse
regulation of transmembrane transport	GO:0034762	128	0.030
positive regulation of protein kinase activity	GO:0045860	144	0.030	Human
microtubule based process	GO:0007017	236	0.030
extrinsic apoptotic signaling pathway	GO:0097191	126	0.030
regulation of embryonic development	GO:0045995	71	0.029
locomotory behavior	GO:0007626	195	0.029
axonogenesis	GO:0007409	274	0.029
skeletal muscle organ development	GO:0060538	163	0.029
blood vessel morphogenesis	GO:0048514	285	0.029
positive regulation of transferase activity	GO:0051347	167	0.029	Human
circadian rhythm	GO:0007623	114	0.029
purine containing compound metabolic process	GO:0072521	311	0.029
microtubule cytoskeleton organization	GO:0000226	157	0.029
protein localization to organelle	GO:0033365	185	0.029
cellular nitrogen compound catabolic process	GO:0044270	280	0.029
cellular response to carbohydrate stimulus	GO:0071322	50	0.028
covalent chromatin modification	GO:0016569	163	0.028
neuronal action potential	GO:0019228	54	0.028
glycerolipid metabolic process	GO:0046486	122	0.028
protein modification by small protein conjugation	GO:0032446	187	0.028	Mouse
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.028
purine ribonucleoside metabolic process	GO:0046128	241	0.028
response to peptide hormone	GO:0043434	127	0.028
ion transmembrane transport	GO:0034220	361	0.028
retina development in camera type eye	GO:0060041	119	0.028
gliogenesis	GO:0042063	141	0.028
protein catabolic process	GO:0030163	221	0.028	Mouse
glycosyl compound metabolic process	GO:1901657	246	0.028
regulation of lymphocyte proliferation	GO:0050670	117	0.028	Mouse
regulation of system process	GO:0044057	200	0.028
translation	GO:0006412	93	0.028
digestive tract morphogenesis	GO:0048546	147	0.028	Fly
epidermis development	GO:0008544	187	0.027
ear morphogenesis	GO:0042471	118	0.027
inner ear morphogenesis	GO:0042472	101	0.027
negative regulation of cell morphogenesis involved in differentiation	GO:0010771	48	0.027
negative regulation of cell cycle	GO:0045786	123	0.027
monocarboxylic acid metabolic process	GO:0032787	191	0.027
regulation of nucleoside metabolic process	GO:0009118	130	0.027
canonical wnt signaling pathway	GO:0060070	130	0.027
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.027
cellular response to hormone stimulus	GO:0032870	150	0.027
oocyte axis specification	GO:0007309	2	0.027
positive regulation of hydrolase activity	GO:0051345	148	0.026
steroid metabolic process	GO:0008202	119	0.026
ribonucleoside metabolic process	GO:0009119	245	0.026
protein targeting	GO:0006605	143	0.026
peptidyl tyrosine phosphorylation	GO:0018108	143	0.026
meiotic nuclear division	GO:0007126	115	0.026
chemotaxis	GO:0006935	247	0.026
cellular response to cytokine stimulus	GO:0071345	189	0.026	Mouse
regulation of cell motility	GO:2000145	236	0.026
myeloid leukocyte differentiation	GO:0002573	119	0.026	Mouse
single organism cell adhesion	GO:0098602	156	0.026
purine ribonucleotide catabolic process	GO:0009154	208	0.026
aromatic compound catabolic process	GO:0019439	286	0.026
glial cell differentiation	GO:0010001	131	0.026
response to organonitrogen compound	GO:0010243	246	0.026
transmission of nerve impulse	GO:0019226	76	0.026
negative regulation of cellular component organization	GO:0051129	194	0.025
germ cell development	GO:0007281	185	0.025
carbohydrate derivative catabolic process	GO:1901136	231	0.025
negative regulation of translational initiation	GO:0045947	4	0.025
cation transmembrane transport	GO:0098655	266	0.025
purine nucleotide metabolic process	GO:0006163	302	0.025
negative regulation of phosphorus metabolic process	GO:0010563	184	0.025
angiogenesis	GO:0001525	201	0.025
regulation of establishment of protein localization	GO:0070201	181	0.025	Mouse
negative regulation of immune system process	GO:0002683	209	0.025
multicellular organismal signaling	GO:0035637	91	0.025
purine containing compound catabolic process	GO:0072523	213	0.025
regulation of muscle tissue development	GO:1901861	97	0.025
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.025
positive regulation of cell development	GO:0010720	237	0.025
ribose phosphate metabolic process	GO:0019693	291	0.025
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.025
response to acid chemical	GO:0001101	111	0.025
regulation of stem cell proliferation	GO:0072091	78	0.025
regulation of t cell proliferation	GO:0042129	92	0.025	Mouse
response to peptide	GO:1901652	136	0.025
cellular response to organonitrogen compound	GO:0071417	145	0.025
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.025	Mouse
innate immune response	GO:0045087	157	0.025	Mouse
jnk cascade	GO:0007254	72	0.025	Human Mouse Fly
regulation of nucleotide metabolic process	GO:0006140	169	0.025
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.024
cellular response to lipid	GO:0071396	145	0.024	Mouse
cellular response to abiotic stimulus	GO:0071214	56	0.024
response to light stimulus	GO:0009416	135	0.024
central nervous system neuron differentiation	GO:0021953	162	0.024
cellular response to glucose stimulus	GO:0071333	45	0.024
bone development	GO:0060348	120	0.024
connective tissue development	GO:0061448	179	0.024
cell maturation	GO:0048469	127	0.024
regulation of protein localization	GO:0032880	231	0.024	Mouse
nucleotide metabolic process	GO:0009117	332	0.024
epithelial cell development	GO:0002064	159	0.024	Fly
stress activated mapk cascade	GO:0051403	80	0.024	Human Mouse Fly
inorganic ion transmembrane transport	GO:0098660	234	0.024
regulation of proteolysis	GO:0030162	164	0.024	Mouse
fat cell differentiation	GO:0045444	160	0.024
metencephalon development	GO:0022037	89	0.024
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.024
protein maturation	GO:0051604	176	0.024
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.024
negative regulation of kinase activity	GO:0033673	81	0.024
guanosine containing compound metabolic process	GO:1901068	144	0.024
stem cell maintenance	GO:0019827	130	0.023
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.023
kidney development	GO:0001822	213	0.023
gastrulation	GO:0007369	116	0.023	Fly
cellular response to dna damage stimulus	GO:0006974	207	0.023
generation of precursor metabolites and energy	GO:0006091	103	0.023
positive regulation of gtpase activity	GO:0043547	85	0.023
cytokine production	GO:0001816	319	0.023	Mouse
limb morphogenesis	GO:0035108	149	0.023
regulation of circadian rhythm	GO:0042752	58	0.023
respiratory tube development	GO:0030323	167	0.023
regulation of cellular component size	GO:0032535	121	0.023
compound eye development	GO:0048749	1	0.022
regulation of neuron projection development	GO:0010975	169	0.022
regulation of map kinase activity	GO:0043405	120	0.022
production of molecular mediator of immune response	GO:0002440	103	0.022	Mouse
lateral inhibition	GO:0046331	1	0.022
cellular glucose homeostasis	GO:0001678	52	0.022
cellular macromolecule catabolic process	GO:0044265	206	0.022
chondrocyte differentiation	GO:0002062	72	0.022
single organism nuclear import	GO:1902593	95	0.022
nucleoside metabolic process	GO:0009116	246	0.022
regulation of cholesterol homeostasis	GO:2000188	9	0.022
maintenance of location	GO:0051235	89	0.022
regulation of nucleotide catabolic process	GO:0030811	122	0.022
carboxylic acid biosynthetic process	GO:0046394	86	0.022
mesenchyme development	GO:0060485	152	0.022
positive regulation of stress activated mapk cascade	GO:0032874	48	0.022	Human Fly
inflammatory response	GO:0006954	244	0.022
negative regulation of cellular amine metabolic process	GO:0033239	1	0.022
cerebral cortex development	GO:0021987	86	0.022
single organismal cell cell adhesion	GO:0016337	131	0.022
positive regulation of nervous system development	GO:0051962	221	0.022
positive regulation of organelle organization	GO:0010638	128	0.022
histone modification	GO:0016570	159	0.021
cognition	GO:0050890	149	0.021
regulation of inflammatory response	GO:0050727	147	0.021
establishment or maintenance of cytoskeleton polarity	GO:0030952	2	0.021
odontogenesis of dentin containing tooth	GO:0042475	66	0.021	Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.021	Mouse
positive regulation of epithelial cell proliferation involved in lung morphogenesis	GO:0060501	3	0.021
small molecule biosynthetic process	GO:0044283	132	0.021
organophosphate catabolic process	GO:0046434	232	0.021
neuron migration	GO:0001764	122	0.021
motor neuron axon guidance	GO:0008045	26	0.021
positive regulation of cell activation	GO:0050867	158	0.021	Mouse
cellular response to acid chemical	GO:0071229	68	0.021
embryonic skeletal system morphogenesis	GO:0048704	91	0.021
telencephalon development	GO:0021537	186	0.021
regulation of ion transport	GO:0043269	215	0.021
cell division	GO:0051301	120	0.021
branching morphogenesis of an epithelial tube	GO:0048754	159	0.021
metal ion homeostasis	GO:0055065	189	0.021
regulation of actin cytoskeleton organization	GO:0032956	84	0.021
regulation of wnt signaling pathway	GO:0030111	123	0.021
organic hydroxy compound metabolic process	GO:1901615	203	0.021
protein localization to membrane	GO:0072657	108	0.021
negative regulation of growth	GO:0045926	99	0.021
negative regulation of synapse assembly	GO:0051964	3	0.021
regulation of cysteine type endopeptidase activity	GO:2000116	65	0.020
response to radiation	GO:0009314	165	0.020
reactive oxygen species metabolic process	GO:0072593	84	0.020
nucleoside phosphate catabolic process	GO:1901292	222	0.020
cellular response to peptide hormone stimulus	GO:0071375	92	0.020
mammary gland epithelium development	GO:0061180	65	0.020
t cell proliferation	GO:0042098	120	0.020	Mouse
positive regulation of t cell activation	GO:0050870	101	0.020	Mouse
intracellular protein transport	GO:0006886	204	0.020
anion transmembrane transport	GO:0098656	71	0.020
regulation of t cell activation	GO:0050863	170	0.020	Mouse
epithelial tube formation	GO:0072175	130	0.020	Mouse
cellular ion homeostasis	GO:0006873	165	0.020
mapk cascade	GO:0000165	281	0.020	Human Mouse Fly
positive regulation of homeostatic process	GO:0032846	64	0.020
regulation of mitotic cell cycle	GO:0007346	126	0.020
tube closure	GO:0060606	91	0.020	Mouse
organic anion transport	GO:0015711	137	0.020
organelle assembly	GO:0070925	177	0.020
cellular response to arsenic containing substance	GO:0071243	4	0.020
regulation of lymphocyte activation	GO:0051249	240	0.020	Mouse
neural precursor cell proliferation	GO:0061351	121	0.020
positive regulation of cytokine production	GO:0001819	174	0.020	Mouse
nucleoside triphosphate metabolic process	GO:0009141	230	0.019
cell cell junction organization	GO:0045216	72	0.019	Fly
anion transport	GO:0006820	177	0.019
ameboidal type cell migration	GO:0001667	128	0.019
ensheathment of neurons	GO:0007272	76	0.019
monocarboxylic acid biosynthetic process	GO:0072330	61	0.019
cellular component assembly involved in morphogenesis	GO:0010927	139	0.019
erythrocyte differentiation	GO:0030218	88	0.019
learning or memory	GO:0007611	148	0.019
asymmetric stem cell division	GO:0098722	3	0.019
regulation of stem cell differentiation	GO:2000736	50	0.019
purine nucleoside catabolic process	GO:0006152	205	0.019
positive regulation of gtp catabolic process	GO:0033126	85	0.019
regulation of gtp catabolic process	GO:0033124	113	0.019
intrinsic apoptotic signaling pathway in response to dna damage	GO:0008630	57	0.019
cell substrate adhesion	GO:0031589	130	0.019
positive regulation of stem cell proliferation	GO:2000648	59	0.019
glucose transport	GO:0015758	56	0.019
limbic system development	GO:0021761	72	0.019
action potential	GO:0001508	78	0.019
spermatid differentiation	GO:0048515	115	0.019
interspecies interaction between organisms	GO:0044419	83	0.019
fatty acid metabolic process	GO:0006631	121	0.019
regulation of actin filament based process	GO:0032970	99	0.019
negative regulation of bmp signaling pathway	GO:0030514	35	0.019
kidney morphogenesis	GO:0060993	83	0.019
protein localization to nucleus	GO:0034504	121	0.019
sensory system development	GO:0048880	3	0.019
positive regulation of leukocyte proliferation	GO:0070665	73	0.019	Mouse
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.019
phospholipid metabolic process	GO:0006644	87	0.018
purine ribonucleotide metabolic process	GO:0009150	290	0.018
meiotic cell cycle	GO:0051321	122	0.018
gtp metabolic process	GO:0046039	144	0.018
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.018
nucleoside phosphate metabolic process	GO:0006753	338	0.018
cellular response to peptide	GO:1901653	92	0.018
regulation of ras protein signal transduction	GO:0046578	114	0.018
cellular response to monosaccharide stimulus	GO:0071326	47	0.018
respiratory system development	GO:0060541	190	0.018
calcium ion transport	GO:0006816	159	0.018
organic hydroxy compound biosynthetic process	GO:1901617	77	0.018
hair follicle development	GO:0001942	85	0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.018
mammary gland morphogenesis	GO:0060443	54	0.018
skin development	GO:0043588	220	0.018
alpha beta t cell activation	GO:0046631	91	0.018
organ growth	GO:0035265	117	0.018
cardiac chamber development	GO:0003205	108	0.018
regulation of epithelial to mesenchymal transition	GO:0010717	22	0.018
organelle localization	GO:0051640	179	0.017
monosaccharide metabolic process	GO:0005996	106	0.017
response to insulin	GO:0032868	100	0.017
regulation of peptidase activity	GO:0052547	96	0.017
segmentation	GO:0035282	93	0.017
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.017
cardiac chamber morphogenesis	GO:0003206	93	0.017
organic acid biosynthetic process	GO:0016053	86	0.017
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.017
oocyte anterior posterior axis specification	GO:0007314	2	0.017
regulation of purine nucleotide metabolic process	GO:1900542	169	0.017
regulation of cytokine production	GO:0001817	266	0.017	Mouse
negative regulation of neuron projection regeneration	GO:0070571	3	0.017
regulation of leukocyte proliferation	GO:0070663	121	0.017	Mouse
regulation of cytoplasmic transport	GO:1903649	112	0.017
glycerolipid biosynthetic process	GO:0045017	50	0.017
hexose metabolic process	GO:0019318	98	0.017
intrahepatic bile duct development	GO:0035622	2	0.017
multicellular organism growth	GO:0035264	161	0.017
ribonucleotide metabolic process	GO:0009259	291	0.017
establishment of protein localization to organelle	GO:0072594	118	0.017
spermatid development	GO:0007286	108	0.017
endomembrane system organization	GO:0010256	147	0.017
cellular protein catabolic process	GO:0044257	155	0.016
ribonucleotide catabolic process	GO:0009261	208	0.016
glycerophospholipid metabolic process	GO:0006650	71	0.016
mammary gland duct morphogenesis	GO:0060603	38	0.016
regulation of cell adhesion	GO:0030155	154	0.016
regulation of canonical wnt signaling pathway	GO:0060828	82	0.016
regulation of myeloid cell differentiation	GO:0045637	96	0.016
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.016
lung development	GO:0030324	164	0.016
positive regulation of jun kinase activity	GO:0043507	30	0.016
blastocyst development	GO:0001824	80	0.016
positive regulation of t cell proliferation	GO:0042102	52	0.016	Mouse
proteasomal protein catabolic process	GO:0010498	98	0.016
positive regulation of nucleoside metabolic process	GO:0045979	91	0.016
ureteric bud development	GO:0001657	94	0.016
ribonucleoside catabolic process	GO:0042454	206	0.016
chromatin organization	GO:0006325	206	0.016
sequestering of metal ion	GO:0051238	19	0.016
engulfment of apoptotic cell	GO:0043652	3	0.016
detection of stimulus	GO:0051606	84	0.016
neuron death	GO:0070997	154	0.016
regulation of adaptive immune response	GO:0002819	90	0.016
positive regulation of nucleotide metabolic process	GO:0045981	114	0.016
positive regulation of growth	GO:0045927	104	0.016
regulation of anatomical structure size	GO:0090066	178	0.016
blood circulation	GO:0008015	195	0.016
divalent inorganic cation transport	GO:0072511	178	0.016
response to oxidative stress	GO:0006979	123	0.015	Mouse
mesenchymal cell development	GO:0014031	93	0.015
positive regulation of lipid metabolic process	GO:0045834	40	0.015
cardiac muscle tissue development	GO:0048738	130	0.015
sensory perception of mechanical stimulus	GO:0050954	107	0.015
regulation of endopeptidase activity	GO:0052548	89	0.015
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	GO:0061350	2	0.015
organelle fission	GO:0048285	170	0.015
regulation of purine nucleotide catabolic process	GO:0033121	122	0.015
somatic stem cell maintenance	GO:0035019	47	0.015
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	GO:0060528	4	0.015
axial mesoderm formation	GO:0048320	3	0.015
negative regulation of transferase activity	GO:0051348	85	0.015
response to temperature stimulus	GO:0009266	55	0.015
cellular response to insulin stimulus	GO:0032869	78	0.015
cell junction organization	GO:0034330	77	0.015	Fly
carbohydrate derivative biosynthetic process	GO:1901137	183	0.015
negative regulation of osteoblast differentiation	GO:0045668	30	0.015
nucleocytoplasmic transport	GO:0006913	139	0.015
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.015
cellular protein complex assembly	GO:0043623	116	0.015	Mouse
insulin secretion involved in cellular response to glucose stimulus	GO:0035773	36	0.015
actin filament organization	GO:0007015	113	0.015
positive regulation of proteolysis	GO:0045862	85	0.015
regulation of t cell differentiation	GO:0045580	83	0.015
cellular response to molecule of bacterial origin	GO:0071219	83	0.015	Mouse

Traf4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.020
nervous system disease	DOID:863	0.019
disease of anatomical entity	DOID:7	0.019

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