IMP: Integrative Multi-species Prediction

Mus musculus

138 known processes

Pard3

par-3 (partitioning defective 3) homolog (C. elegans)

(Aliases: D8Ertd580e,AA960621,Par3,Pard3a,AI256638,PAR-3,ASIP)

Entrez: 93742
Ensembl: ENSMUSG00000025812
UniProtKB: B2RUK1
UniProtKB: A5D6P2
UniProtKB: E9PYJ2
UniProtKB: G3XA13
UniProtKB: Q99NH2
UniProtKB: B7ZNY3

Process Predictions
Disease Predictions

Pard3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cell adhesion	GO:0007155	329	0.942	Worm Fly
single organismal cell cell adhesion	GO:0016337	131	0.850	Fly
amine metabolic process	GO:0009308	45	0.823
establishment of mitochondrion localization	GO:0051654	4	0.801
regulation of endothelial cell migration	GO:0010594	22	0.754
retina morphogenesis in camera type eye	GO:0060042	45	0.747
regulation of ras gtpase activity	GO:0032318	88	0.689
germ cell development	GO:0007281	185	0.670	Fly
regulation of actin filament length	GO:0030832	45	0.668
t cell proliferation	GO:0042098	120	0.665
regulation of actin cytoskeleton organization	GO:0032956	84	0.652
sensory organ morphogenesis	GO:0090596	242	0.644
regulation of cellular amino acid metabolic process	GO:0006521	5	0.626
regulation of t cell proliferation	GO:0042129	92	0.626
actin polymerization or depolymerization	GO:0008154	54	0.624
single organism cell adhesion	GO:0098602	156	0.618	Fly
cellular amine metabolic process	GO:0044106	44	0.616
camera type eye development	GO:0043010	266	0.611
regulation of actin polymerization or depolymerization	GO:0008064	45	0.605
retina development in camera type eye	GO:0060041	119	0.605
glial cell differentiation	GO:0010001	131	0.596
actin cytoskeleton organization	GO:0030036	220	0.582
leukocyte proliferation	GO:0070661	172	0.576
regulation of actin filament based process	GO:0032970	99	0.569
regulation of nucleotide catabolic process	GO:0030811	122	0.516
cellular ketone metabolic process	GO:0042180	84	0.510
positive regulation of phospholipase activity	GO:0010518	3	0.508
regulation of interleukin 10 secretion	GO:2001179	4	0.507
vesicle organization	GO:0016050	60	0.476
regulation of cell migration	GO:0030334	219	0.475
ameboidal type cell migration	GO:0001667	128	0.465	Fly
developmental maturation	GO:0021700	193	0.461	Fly
regulation of protein kinase activity	GO:0045859	232	0.448
t helper 2 cell cytokine production	GO:0035745	4	0.446
regulation of kinase activity	GO:0043549	249	0.445
organelle localization	GO:0051640	179	0.436
schwann cell development	GO:0014044	22	0.433
cell cell junction organization	GO:0045216	72	0.427	Rat Fly
regulation of blood vessel endothelial cell migration	GO:0043535	12	0.426
positive regulation of mapk cascade	GO:0043410	170	0.418
organelle assembly	GO:0070925	177	0.416
nucleoside triphosphate metabolic process	GO:0009141	230	0.416
homophilic cell adhesion via plasma membrane adhesion molecules	GO:0007156	18	0.405
vesicle transport along microtubule	GO:0047496	9	0.405
regulation of lymphocyte proliferation	GO:0050670	117	0.397
actin filament polymerization	GO:0030041	44	0.392
secretory granule organization	GO:0033363	20	0.390
neuron projection guidance	GO:0097485	141	0.387
endomembrane system organization	GO:0010256	147	0.374
cellular amino acid metabolic process	GO:0006520	103	0.373
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.373
regulation of cysteine type endopeptidase activity	GO:2000116	65	0.368
ensheathment of neurons	GO:0007272	76	0.362
cell cell adhesion	GO:0098609	41	0.362
glial cell development	GO:0021782	54	0.362
skin development	GO:0043588	220	0.361
establishment of monopolar cell polarity	GO:0061162	8	0.355	Fly
photoreceptor cell differentiation	GO:0046530	52	0.351	Fly
axonogenesis	GO:0007409	274	0.350
heterocycle catabolic process	GO:0046700	280	0.345
organonitrogen compound catabolic process	GO:1901565	264	0.343
mitochondrion organization	GO:0007005	134	0.337
establishment or maintenance of bipolar cell polarity	GO:0061245	21	0.333	Fly
cellular response to cytokine stimulus	GO:0071345	189	0.326
regulation of leukocyte proliferation	GO:0070663	121	0.324
epithelium migration	GO:0090132	63	0.323	Fly
regulation of cytoskeleton organization	GO:0051493	122	0.320
guanosine containing compound metabolic process	GO:1901068	144	0.319
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules	GO:0007157	20	0.318
negative regulation of cellular amine metabolic process	GO:0033239	1	0.315
actin filament organization	GO:0007015	113	0.311
epithelial cell migration	GO:0010631	63	0.309	Fly
epidermis development	GO:0008544	187	0.307
mapk cascade	GO:0000165	281	0.306
positive regulation of insulin receptor signaling pathway	GO:0046628	4	0.302
regulation of transferase activity	GO:0051338	263	0.300
regulation of actin filament polymerization	GO:0030833	38	0.300
regulation of cd4 positive alpha beta t cell activation	GO:2000514	24	0.299
regulation of mapk cascade	GO:0043408	248	0.298
organophosphate catabolic process	GO:0046434	232	0.295
cellular component assembly involved in morphogenesis	GO:0010927	139	0.293
nucleoside triphosphate catabolic process	GO:0009143	205	0.287
vesicle localization	GO:0051648	86	0.284
negative regulation of cellular protein metabolic process	GO:0032269	247	0.284
cellular protein catabolic process	GO:0044257	155	0.283
negative regulation of insulin receptor signaling pathway	GO:0046627	14	0.282
multi multicellular organism process	GO:0044706	109	0.277
gliogenesis	GO:0042063	141	0.275
ras protein signal transduction	GO:0007265	77	0.263
positive regulation of t cell activation	GO:0050870	101	0.263
protein localization to membrane	GO:0072657	108	0.262	Rat
regulation of membrane potential	GO:0042391	192	0.261
regulation of lymphocyte activation	GO:0051249	240	0.257
b cell activation	GO:0042113	161	0.257
endothelial cell migration	GO:0043542	44	0.256
muscle tissue development	GO:0060537	308	0.254
ubiquitin dependent protein catabolic process	GO:0006511	129	0.248
gtp metabolic process	GO:0046039	144	0.246
cell cell adhesion via plasma membrane adhesion molecules	GO:0098742	40	0.246
myelination in peripheral nervous system	GO:0022011	19	0.246
filopodium assembly	GO:0046847	19	0.244	Fly
regulation of t cell activation	GO:0050863	170	0.243
mrna 3 end processing	GO:0031124	16	0.240
interleukin 5 secretion	GO:0072603	2	0.239
regulation of cellular amine metabolic process	GO:0033238	20	0.238
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.235
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.235
muscle cell differentiation	GO:0042692	261	0.235
purine ribonucleoside catabolic process	GO:0046130	205	0.232
regulation of apoptotic signaling pathway	GO:2001233	197	0.229
interleukin 10 secretion	GO:0072608	4	0.225
eye photoreceptor cell development	GO:0042462	31	0.224
regulation of ral gtpase activity	GO:0032315	4	0.224
energy reserve metabolic process	GO:0006112	39	0.224
positive regulation of t cell proliferation	GO:0042102	52	0.223
odontogenesis of dentin containing tooth	GO:0042475	66	0.222
central nervous system neuron differentiation	GO:0021953	162	0.222
negative regulation of cell proliferation	GO:0008285	296	0.221
positive regulation of leukocyte proliferation	GO:0070665	73	0.220
positive regulation of protein kinase activity	GO:0045860	144	0.219
peptidyl amino acid modification	GO:0018193	336	0.218
angiogenesis	GO:0001525	201	0.216
action potential	GO:0001508	78	0.214
protein modification by small protein conjugation	GO:0032446	187	0.214
nerve development	GO:0021675	67	0.214
regulation of gtp catabolic process	GO:0033124	113	0.212
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.212
modification dependent protein catabolic process	GO:0019941	133	0.212
positive regulation of gtpase activity	GO:0043547	85	0.207
regulation of cell projection assembly	GO:0060491	38	0.199	Fly
regulation of ras protein signal transduction	GO:0046578	114	0.198
positive regulation of nucleoside metabolic process	GO:0045979	91	0.198
multicellular organismal signaling	GO:0035637	91	0.197
negative regulation of molecular function	GO:0044092	258	0.194
cytoskeleton dependent intracellular transport	GO:0030705	50	0.193
positive regulation of lymphocyte proliferation	GO:0050671	70	0.191
primary neural tube formation	GO:0014020	95	0.191
tissue migration	GO:0090130	68	0.190	Fly
t cell activation	GO:0042110	289	0.189
striated muscle tissue development	GO:0014706	293	0.187
regulation of protein transport	GO:0051223	163	0.187
regulation of protein serine threonine kinase activity	GO:0071900	157	0.186
regulation of epithelial cell migration	GO:0010632	35	0.185
negative regulation of cell activation	GO:0050866	111	0.183
regulation of cell motility	GO:2000145	236	0.182
establishment or maintenance of cell polarity	GO:0007163	86	0.181	Rat Worm Fly
modification dependent macromolecule catabolic process	GO:0043632	133	0.181
negative regulation of filopodium assembly	GO:0051490	2	0.179	Fly
establishment or maintenance of apical basal cell polarity	GO:0035088	21	0.179	Fly
cellular response to growth factor stimulus	GO:0071363	197	0.177
nucleoside catabolic process	GO:0009164	206	0.172
regulation of endopeptidase activity	GO:0052548	89	0.171
regulation of t cell differentiation	GO:0045580	83	0.171
axon guidance	GO:0007411	141	0.170
purine ribonucleotide catabolic process	GO:0009154	208	0.169
negative regulation of phosphate metabolic process	GO:0045936	184	0.169
regulation of organelle organization	GO:0033043	289	0.169
retinal blood vessel morphogenesis	GO:0061304	3	0.168
gtp catabolic process	GO:0006184	143	0.168
central nervous system projection neuron axonogenesis	GO:0021952	21	0.167
positive regulation of lymphocyte activation	GO:0051251	140	0.167
positive regulation of apoptotic process	GO:0043065	217	0.166
carbohydrate homeostasis	GO:0033500	128	0.165
spermatogenesis	GO:0007283	284	0.165
cellular response to peptide	GO:1901653	92	0.163
organelle transport along microtubule	GO:0072384	14	0.162
regulation of cell adhesion	GO:0030155	154	0.162	Fly
regulation of cellular catabolic process	GO:0031329	242	0.162
synaptic transmission	GO:0007268	329	0.162
regulation of cell migration involved in sprouting angiogenesis	GO:0090049	4	0.159
regulation of cellular ketone metabolic process	GO:0010565	66	0.158
neuronal action potential	GO:0019228	54	0.158
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.158
nucleotide catabolic process	GO:0009166	217	0.158
macromolecule catabolic process	GO:0009057	281	0.157
ribonucleotide metabolic process	GO:0009259	291	0.156
ribonucleoside catabolic process	GO:0042454	206	0.156
apoptotic signaling pathway	GO:0097190	306	0.156
negative regulation of cellular component organization	GO:0051129	194	0.156	Fly
rac protein signal transduction	GO:0016601	13	0.155
negative regulation of cell projection organization	GO:0031345	56	0.155	Fly
guanosine containing compound catabolic process	GO:1901069	144	0.154
mitochondrion localization	GO:0051646	9	0.153
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.150
t cell differentiation	GO:0030217	174	0.150
microtubule based movement	GO:0007018	84	0.150
lymphocyte differentiation	GO:0030098	242	0.149
peptidyl tyrosine phosphorylation	GO:0018108	143	0.148
regulation of ral protein signal transduction	GO:0032485	4	0.148
lens morphogenesis in camera type eye	GO:0002089	24	0.148
cell matrix adhesion	GO:0007160	68	0.148
regulation of hydrolase activity	GO:0051336	246	0.146
regulation of nucleoside metabolic process	GO:0009118	130	0.145
regulation of cell activation	GO:0050865	289	0.145
carbohydrate derivative catabolic process	GO:1901136	231	0.144
regulation of interleukin 2 biosynthetic process	GO:0045076	13	0.143
neuron projection extension	GO:1990138	64	0.141
negative regulation of phosphorus metabolic process	GO:0010563	184	0.141
regulation of vasculature development	GO:1901342	88	0.140
adaptive immune response	GO:0002250	155	0.139
epithelial cell proliferation	GO:0050673	174	0.139
establishment of vesicle localization	GO:0051650	81	0.138
immune effector process	GO:0002252	321	0.138
desmosome organization	GO:0002934	5	0.137
establishment of organelle localization	GO:0051656	122	0.137	Worm
regulation of cellular component size	GO:0032535	121	0.137
regulation of glucose transport	GO:0010827	32	0.136
placenta development	GO:0001890	140	0.135
positive regulation of protein modification process	GO:0031401	299	0.133
digestive tract development	GO:0048565	190	0.133	Worm Fly
positive regulation of t helper 2 cell cytokine production	GO:2000553	3	0.132
regulation of epithelial cell proliferation	GO:0050678	141	0.131
purine containing compound catabolic process	GO:0072523	213	0.131
interleukin 13 secretion	GO:0072611	2	0.130
monosaccharide metabolic process	GO:0005996	106	0.130
regulation of angiogenesis	GO:0045765	81	0.130
positive regulation of cellular catabolic process	GO:0031331	148	0.127
lens development in camera type eye	GO:0002088	62	0.126
positive regulation of cell activation	GO:0050867	158	0.126
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.125
neural tube formation	GO:0001841	108	0.123
protein ubiquitination	GO:0016567	171	0.123
cognition	GO:0050890	149	0.123
microtubule cytoskeleton organization	GO:0000226	157	0.122
oxidation reduction process	GO:0055114	342	0.122
regulation of alpha beta t cell activation	GO:0046634	53	0.121
cytokine production	GO:0001816	319	0.121
regulation of secretion by cell	GO:1903530	249	0.121
positive regulation of alpha beta t cell differentiation	GO:0046638	28	0.121
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.120
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	62	0.119
glucose import in response to insulin stimulus	GO:0044381	8	0.119
endocardial cushion to mesenchymal transition involved in heart valve formation	GO:0003199	4	0.118
blood vessel morphogenesis	GO:0048514	285	0.118
purine nucleoside catabolic process	GO:0006152	205	0.117
keratinocyte proliferation	GO:0043616	21	0.117
fertilization	GO:0009566	127	0.115
regulation of nucleotide metabolic process	GO:0006140	169	0.115
organic cyclic compound catabolic process	GO:1901361	295	0.115
regulation of anatomical structure size	GO:0090066	178	0.114
anatomical structure maturation	GO:0071695	49	0.114
protein heterooligomerization	GO:0051291	14	0.114
neural tube development	GO:0021915	160	0.113
wound healing	GO:0042060	157	0.112
epithelial tube morphogenesis	GO:0060562	303	0.112	Fly
gland development	GO:0048732	330	0.111
spermatid development	GO:0007286	108	0.111
cellular response to insulin stimulus	GO:0032869	78	0.111
regulation of interleukin 5 secretion	GO:2000662	2	0.111
regulation of keratinocyte proliferation	GO:0010837	15	0.110
response to epidermal growth factor	GO:0070849	4	0.109
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.109
purine nucleotide metabolic process	GO:0006163	302	0.109
ribose phosphate metabolic process	GO:0019693	291	0.107
cell substrate adhesion	GO:0031589	130	0.107
regulation of cell projection organization	GO:0031344	206	0.106	Fly
regulation of establishment of protein localization	GO:0070201	181	0.106
purine nucleotide catabolic process	GO:0006195	211	0.105
regulation of protein localization	GO:0032880	231	0.105
protein targeting	GO:0006605	143	0.105	Rat
positive regulation of organelle organization	GO:0010638	128	0.105
regulation of purine nucleotide catabolic process	GO:0033121	122	0.104
nucleus localization	GO:0051647	20	0.104
nuclear transcribed mrna catabolic process deadenylation dependent decay	GO:0000288	12	0.104
nephron development	GO:0072006	109	0.103
renal system development	GO:0072001	225	0.103	Fly
peptidyl tyrosine modification	GO:0018212	145	0.103
membrane fusion	GO:0061025	38	0.101
regulation of cellular component biogenesis	GO:0044087	181	0.101	Fly
axon ensheathment	GO:0008366	76	0.100
regulation of intracellular transport	GO:0032386	159	0.100
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.100
response to insulin	GO:0032868	100	0.099
response to peptide hormone	GO:0043434	127	0.099
urogenital system development	GO:0001655	261	0.098	Fly
regulation of nuclear transcribed mrna poly a tail shortening	GO:0060211	4	0.098
male gamete generation	GO:0048232	285	0.098
cellular macromolecule catabolic process	GO:0044265	206	0.098
negative regulation of hydrolase activity	GO:0051346	71	0.097
leukocyte differentiation	GO:0002521	342	0.097
purine nucleoside metabolic process	GO:0042278	241	0.097
protein polymerization	GO:0051258	57	0.096
positive regulation of protein phosphorylation	GO:0001934	242	0.095
digestive tract morphogenesis	GO:0048546	147	0.095	Worm Fly
stem cell differentiation	GO:0048863	268	0.095
microtubule based transport	GO:0010970	50	0.095
cell junction organization	GO:0034330	77	0.094	Rat Fly
interleukin 4 production	GO:0032633	24	0.094
skeletal system development	GO:0001501	356	0.094
negative regulation of dendritic spine morphogenesis	GO:0061002	3	0.094
glycosyl compound catabolic process	GO:1901658	206	0.094
insulin receptor signaling pathway	GO:0008286	49	0.094
negative regulation of transferase activity	GO:0051348	85	0.094
kidney development	GO:0001822	213	0.092
myeloid cell differentiation	GO:0030099	233	0.092
ribonucleoside metabolic process	GO:0009119	245	0.092
positive regulation of intracellular transport	GO:0032388	70	0.090
morphogenesis of a branching structure	GO:0001763	203	0.090	Fly
ribonucleotide catabolic process	GO:0009261	208	0.090
cytokine biosynthetic process	GO:0042089	68	0.090
cell migration involved in sprouting angiogenesis	GO:0002042	9	0.089
positive regulation of kinase activity	GO:0033674	155	0.089
alpha beta t cell differentiation	GO:0046632	69	0.089
regulation of interleukin 4 production	GO:0032673	18	0.088
negative regulation of cellular response to insulin stimulus	GO:1900077	16	0.088
regulation of interleukin 13 secretion	GO:2000665	2	0.088
regulation of peptidase activity	GO:0052547	96	0.087
glucose metabolic process	GO:0006006	92	0.086
release of cytochrome c from mitochondria	GO:0001836	23	0.085
innervation	GO:0060384	22	0.085
glucose homeostasis	GO:0042593	128	0.084
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.084
protein catabolic process	GO:0030163	221	0.084
negative regulation of proteolysis	GO:0045861	74	0.084
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.083
embryonic organ morphogenesis	GO:0048562	276	0.083
positive regulation of production of molecular mediator of immune response	GO:0002702	45	0.082
negative regulation of dendritic spine development	GO:0061000	3	0.082
cellular response to peptide hormone stimulus	GO:0071375	92	0.082
regulation of protein targeting	GO:1903533	61	0.081
regulation of bmp signaling pathway	GO:0030510	60	0.081
nucleotide metabolic process	GO:0009117	332	0.081
sprouting angiogenesis	GO:0002040	26	0.081
positive regulation of intracellular protein transport	GO:0090316	42	0.081
oocyte construction	GO:0007308	2	0.080	Fly
eye photoreceptor cell differentiation	GO:0001754	41	0.080
labyrinthine layer development	GO:0060711	49	0.080
hair cycle phase	GO:0044851	16	0.079
cd4 positive alpha beta t cell activation	GO:0035710	45	0.079
nitrogen compound transport	GO:0071705	271	0.079
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.079
positive regulation of interleukin 5 secretion	GO:2000664	1	0.078
small gtpase mediated signal transduction	GO:0007264	97	0.078
aromatic compound catabolic process	GO:0019439	286	0.078
t helper cell differentiation	GO:0042093	28	0.077
ossification	GO:0001503	216	0.076
membrane organization	GO:0061024	245	0.076	Rat
chemotaxis	GO:0006935	247	0.076
response to peptide	GO:1901652	136	0.076
cell activation involved in immune response	GO:0002263	126	0.076
acrosome assembly	GO:0001675	11	0.075
cellular nitrogen compound catabolic process	GO:0044270	280	0.075
motor neuron axon guidance	GO:0008045	26	0.075
digestive system development	GO:0055123	200	0.075	Worm Fly
protein modification by small protein conjugation or removal	GO:0070647	207	0.074
immunoglobulin mediated immune response	GO:0016064	69	0.074
protein oligomerization	GO:0051259	67	0.074
positive regulation of ras gtpase activity	GO:0032320	65	0.073
alpha beta t cell activation	GO:0046631	91	0.073
positive regulation of leukocyte differentiation	GO:1902107	86	0.073
plasma membrane organization	GO:0007009	90	0.073
cardiocyte differentiation	GO:0035051	87	0.073
rho protein signal transduction	GO:0007266	32	0.072
cytokine production involved in immune response	GO:0002367	34	0.072
actin filament based movement	GO:0030048	23	0.072
regulation of cell substrate adhesion	GO:0010810	73	0.072
b cell proliferation	GO:0042100	53	0.072
autophagy	GO:0006914	45	0.071
negative regulation of kinase activity	GO:0033673	81	0.071
negative regulation of phosphorylation	GO:0042326	166	0.071
regulation of lymphocyte differentiation	GO:0045619	107	0.071
negative regulation of organelle organization	GO:0010639	90	0.071
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.070
positive regulation of cell death	GO:0010942	224	0.070
positive regulation of cell adhesion	GO:0045785	80	0.070
regulation of hippo signaling	GO:0035330	1	0.070
dephosphorylation	GO:0016311	129	0.069
ephrin receptor signaling pathway	GO:0048013	20	0.069
compound eye development	GO:0048749	1	0.069
response to growth factor	GO:0070848	198	0.069
regulation of hormone levels	GO:0010817	211	0.069
cellular response to epidermal growth factor stimulus	GO:0071364	4	0.068
nucleoside phosphate catabolic process	GO:1901292	222	0.068
mitral valve morphogenesis	GO:0003183	4	0.068
positive regulation of t cell differentiation	GO:0045582	52	0.067
regulation of homotypic cell cell adhesion	GO:0034110	13	0.067
central nervous system neuron development	GO:0021954	67	0.067
regulation of proteolysis	GO:0030162	164	0.067
anagen	GO:0042640	13	0.067
negative regulation of epithelial cell proliferation	GO:0050680	64	0.067
regulation of neuron projection development	GO:0010975	169	0.066
interleukin 2 biosynthetic process	GO:0042094	15	0.066
t helper 2 cell differentiation	GO:0045064	12	0.066
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.066
positive regulation of cellular amine metabolic process	GO:0033240	5	0.066
lymphocyte activation involved in immune response	GO:0002285	93	0.065
transition metal ion transport	GO:0000041	38	0.065
neural crest cell development	GO:0014032	48	0.065
retinal ganglion cell axon guidance	GO:0031290	18	0.065
negative regulation of cysteine type endopeptidase activity	GO:2000117	22	0.065
memory	GO:0007613	58	0.065
hair cycle	GO:0042633	90	0.065
tooth mineralization	GO:0034505	9	0.064
regulation of t helper 2 cell cytokine production	GO:2000551	3	0.064
cellular response to hormone stimulus	GO:0032870	150	0.063
regulation of protein complex assembly	GO:0043254	83	0.063
positive regulation of cytokine production involved in immune response	GO:0002720	19	0.063
positive regulation of gtp catabolic process	GO:0033126	85	0.063
neural tube closure	GO:0001843	90	0.063
regulation of intracellular protein transport	GO:0033157	82	0.062
cellular glucan metabolic process	GO:0006073	32	0.062
regulation of lipase activity	GO:0060191	15	0.062
regulation of stem cell differentiation	GO:2000736	50	0.062
cellular carbohydrate metabolic process	GO:0044262	119	0.062
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.061
defense response to other organism	GO:0098542	197	0.061
cytoplasmic transport	GO:0016482	234	0.061
glucose transport	GO:0015758	56	0.060
t cell mediated immunity	GO:0002456	50	0.060
hexose transport	GO:0008645	56	0.060
t cell differentiation involved in immune response	GO:0002292	30	0.060
metencephalon development	GO:0022037	89	0.059
labyrinthine layer blood vessel development	GO:0060716	21	0.059
cd4 positive alpha beta t cell cytokine production	GO:0035743	4	0.059
t helper 2 cell activation	GO:0035712	2	0.059
regulation of gliogenesis	GO:0014013	50	0.059
negative regulation of stem cell differentiation	GO:2000737	14	0.058
negative regulation of cytoskeleton organization	GO:0051494	36	0.058
glucan metabolic process	GO:0044042	32	0.058
regulation of synaptic plasticity	GO:0048167	87	0.058
positive regulation of cell substrate adhesion	GO:0010811	47	0.058
cardiac muscle cell differentiation	GO:0055007	69	0.058
regulation of cd4 positive alpha beta t cell differentiation	GO:0043370	21	0.057
cardiac cell fate specification	GO:0060912	2	0.057
protein maturation	GO:0051604	176	0.057
negative regulation of protein metabolic process	GO:0051248	282	0.057
female gamete generation	GO:0007292	74	0.057	Worm Fly
establishment of protein localization to membrane	GO:0090150	54	0.057	Rat
positive regulation of interleukin 4 production	GO:0032753	15	0.057
central nervous system neuron axonogenesis	GO:0021955	28	0.057
regulation of mitochondrion organization	GO:0010821	27	0.057
stem cell development	GO:0048864	219	0.056
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.056
positive regulation of programmed cell death	GO:0043068	218	0.056
t cell activation involved in immune response	GO:0002286	43	0.056
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.056
nucleoside metabolic process	GO:0009116	246	0.055
positive regulation of glucose import	GO:0046326	14	0.055
negative regulation of immune system process	GO:0002683	209	0.055
synapse organization	GO:0050808	125	0.055	Fly
cd4 positive alpha beta t cell differentiation	GO:0043367	41	0.054
positive regulation of t helper 2 cell activation	GO:2000570	2	0.054
intracellular protein transport	GO:0006886	204	0.054	Rat
leukocyte mediated immunity	GO:0002443	174	0.054
organic hydroxy compound metabolic process	GO:1901615	203	0.054
defense response to bacterium	GO:0042742	119	0.054
carbohydrate metabolic process	GO:0005975	230	0.054
regulation of protein maturation	GO:1903317	96	0.054
lymphocyte mediated immunity	GO:0002449	139	0.053
glycogen metabolic process	GO:0005977	32	0.052
epithelial cell development	GO:0002064	159	0.052
inner ear receptor cell differentiation	GO:0060113	61	0.052
positive regulation of map kinase activity	GO:0043406	84	0.052
establishment of apical basal cell polarity	GO:0035089	7	0.052	Fly
regulation of wnt signaling pathway	GO:0030111	123	0.051	Fly
proteasomal protein catabolic process	GO:0010498	98	0.051
response to organonitrogen compound	GO:0010243	246	0.051
purine ribonucleotide metabolic process	GO:0009150	290	0.051
epithelial tube formation	GO:0072175	130	0.051
regulation of protein processing	GO:0070613	96	0.051
nucleoside phosphate metabolic process	GO:0006753	338	0.051
regulation of interleukin 2 production	GO:0032663	28	0.051
positive regulation of transferase activity	GO:0051347	167	0.051
lymphocyte proliferation	GO:0046651	164	0.051
salivary gland development	GO:0007431	37	0.051
maternal placenta development	GO:0001893	20	0.051
hair follicle development	GO:0001942	85	0.051
positive regulation of erk1 and erk2 cascade	GO:0070374	47	0.050
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.050
energy derivation by oxidation of organic compounds	GO:0015980	77	0.050
regulation of organ growth	GO:0046620	61	0.050
dendrite development	GO:0016358	115	0.050
positive regulation of protein targeting to membrane	GO:0090314	7	0.049
negative regulation of neuron projection development	GO:0010977	50	0.049
protein kinase b signaling	GO:0043491	74	0.049
canonical wnt signaling pathway	GO:0060070	130	0.049
regulation of leukocyte mediated immunity	GO:0002703	104	0.049
posttranscriptional regulation of gene expression	GO:0010608	155	0.049
regulation of purine nucleotide metabolic process	GO:1900542	169	0.048
spinal cord development	GO:0021510	81	0.048
regulation of feeding behavior	GO:0060259	3	0.048
regulation of neuron differentiation	GO:0045664	281	0.048
negative regulation of protein processing	GO:0010955	79	0.048
rna 3 end processing	GO:0031123	20	0.048
lung development	GO:0030324	164	0.048
cation transport	GO:0006812	399	0.048
multicellular organism growth	GO:0035264	161	0.048
response to pain	GO:0048265	26	0.047
negative regulation of peptidyl tyrosine phosphorylation	GO:0050732	17	0.047
establishment of protein localization to plasma membrane	GO:0090002	34	0.047
interleukin 2 production	GO:0032623	33	0.047
homotypic cell cell adhesion	GO:0034109	28	0.047
alpha beta t cell activation involved in immune response	GO:0002287	31	0.046
negative regulation of protein modification process	GO:0031400	163	0.046
myeloid leukocyte differentiation	GO:0002573	119	0.046
membrane hyperpolarization	GO:0060081	21	0.046
purine ribonucleoside metabolic process	GO:0046128	241	0.046
protein processing	GO:0016485	163	0.046
regulation of protein catabolic process	GO:0042176	108	0.046
embryonic placenta development	GO:0001892	98	0.046

Pard3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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