IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Scara3

scavenger receptor class A, member 3

(Aliases: CSR1,MSRL1,MSLR1,C130058N24Rik,APC7,CSR)

Ensembl: ENSMUSG00000034463
Entrez: 219151
UniProtKB: Q8C850

Process Predictions
Disease Predictions

Scara3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.397
transforming growth factor beta receptor signaling pathway	GO:0007179	71	0.364
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.303
skeletal system development	GO:0001501	356	0.300
ossification	GO:0001503	216	0.261
extracellular structure organization	GO:0043062	148	0.254
response to transforming growth factor beta	GO:0071559	88	0.205
cellular response to amino acid stimulus	GO:0071230	29	0.197
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.169
extracellular matrix organization	GO:0030198	147	0.158
cartilage development	GO:0051216	140	0.123
cell adhesion	GO:0007155	329	0.104
heart morphogenesis	GO:0003007	178	0.102
response to growth factor	GO:0070848	198	0.094
organ growth	GO:0035265	117	0.092
mesonephros development	GO:0001823	97	0.088
response to amino acid	GO:0043200	37	0.086
biomineral tissue development	GO:0031214	64	0.085
bone development	GO:0060348	120	0.083
proteoglycan metabolic process	GO:0006029	38	0.080
cellular response to organonitrogen compound	GO:0071417	145	0.077
response to oxidative stress	GO:0006979	123	0.074
connective tissue development	GO:0061448	179	0.073
renal system development	GO:0072001	225	0.066
developmental growth involved in morphogenesis	GO:0060560	138	0.066
head morphogenesis	GO:0060323	34	0.065
chondrocyte differentiation	GO:0002062	72	0.064
response to organonitrogen compound	GO:0010243	246	0.063
glycoprotein metabolic process	GO:0009100	116	0.062
muscle tissue development	GO:0060537	308	0.060
mesonephric tubule development	GO:0072164	94	0.056
negative regulation of transforming growth factor beta receptor signaling pathway	GO:0030512	26	0.056
protein maturation	GO:0051604	176	0.055
protein processing	GO:0016485	163	0.055
regulation of hydrolase activity	GO:0051336	246	0.054
regulation of system process	GO:0044057	200	0.053
urogenital system development	GO:0001655	261	0.052
respiratory tube development	GO:0030323	167	0.052
rho protein signal transduction	GO:0007266	32	0.052
bone morphogenesis	GO:0060349	78	0.051
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	61	0.051
cellular response to growth factor stimulus	GO:0071363	197	0.051
regulation of removal of superoxide radicals	GO:2000121	4	0.051
digestive system development	GO:0055123	200	0.050
cardiac muscle tissue development	GO:0048738	130	0.049
lung development	GO:0030324	164	0.048
cytokine production	GO:0001816	319	0.048
cartilage development involved in endochondral bone morphogenesis	GO:0060351	24	0.047
cardiac chamber morphogenesis	GO:0003206	93	0.047
positive regulation of cell development	GO:0010720	237	0.047
bmp signaling pathway	GO:0030509	93	0.044
negative regulation of cellular response to growth factor stimulus	GO:0090288	46	0.044
monocarboxylic acid metabolic process	GO:0032787	191	0.044
kidney epithelium development	GO:0072073	121	0.043
cellular response to hormone stimulus	GO:0032870	150	0.043
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	43	0.042
lateral line system development	GO:0048925	1	0.040
skeletal system morphogenesis	GO:0048705	203	0.040
respiratory system development	GO:0060541	190	0.040
regulation of ossification	GO:0030278	112	0.040
muscle system process	GO:0003012	141	0.039
mesonephric epithelium development	GO:0072163	94	0.039
positive regulation of hydrolase activity	GO:0051345	148	0.039
cellular response to acid chemical	GO:0071229	68	0.038
anatomical structure homeostasis	GO:0060249	145	0.038
positive regulation of cell projection organization	GO:0031346	95	0.037
response to acid chemical	GO:0001101	111	0.035
mucopolysaccharide metabolic process	GO:1903510	25	0.035
regulation of hormone levels	GO:0010817	211	0.035
reactive oxygen species metabolic process	GO:0072593	84	0.035
spermatogenesis	GO:0007283	284	0.035
regulation of biomineral tissue development	GO:0070167	33	0.035
oxidation reduction process	GO:0055114	342	0.033
small gtpase mediated signal transduction	GO:0007264	97	0.033
regulation of cytokine production	GO:0001817	266	0.033
ureteric bud development	GO:0001657	94	0.032
negative regulation of immune system process	GO:0002683	209	0.032
female sex differentiation	GO:0046660	84	0.032
skin development	GO:0043588	220	0.032
positive regulation of neuron differentiation	GO:0045666	141	0.032
removal of superoxide radicals	GO:0019430	12	0.032
regionalization	GO:0003002	337	0.031
growth plate cartilage development	GO:0003417	14	0.031
regulation of cellular component biogenesis	GO:0044087	181	0.030
sulfur compound metabolic process	GO:0006790	100	0.030
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.030
telencephalon development	GO:0021537	186	0.030
muscle cell differentiation	GO:0042692	261	0.030
response to superoxide	GO:0000303	16	0.030
transmission of nerve impulse	GO:0019226	76	0.029
sensory system development	GO:0048880	3	0.029
response to organic cyclic compound	GO:0014070	198	0.029
hematopoietic progenitor cell differentiation	GO:0002244	143	0.029
limb morphogenesis	GO:0035108	149	0.029
midgut development	GO:0007494	4	0.029
rhythmic process	GO:0048511	174	0.029
cellular response to superoxide	GO:0071451	14	0.029
embryonic skeletal system development	GO:0048706	120	0.028
nitrogen compound transport	GO:0071705	271	0.028
multicellular organismal homeostasis	GO:0048871	164	0.028
positive regulation of cell adhesion	GO:0045785	80	0.028
physiological cardiac muscle hypertrophy	GO:0003301	3	0.028
response to catecholamine	GO:0071869	4	0.027
cell substrate adhesion	GO:0031589	130	0.027
response to oxygen levels	GO:0070482	62	0.027
positive regulation of nervous system development	GO:0051962	221	0.027
single organismal cell cell adhesion	GO:0016337	131	0.026
negative regulation of cell development	GO:0010721	169	0.026
developmental maturation	GO:0021700	193	0.026
morphogenesis of embryonic epithelium	GO:0016331	159	0.025
kidney development	GO:0001822	213	0.025
cardiocyte differentiation	GO:0035051	87	0.025
axonogenesis	GO:0007409	274	0.024
response to oxygen radical	GO:0000305	16	0.024
endochondral bone morphogenesis	GO:0060350	50	0.024
chemotaxis	GO:0006935	247	0.024
regulation of cell projection organization	GO:0031344	206	0.024
negative regulation of ossification	GO:0030279	49	0.024
elastic fiber assembly	GO:0048251	4	0.023
wnt signaling pathway	GO:0016055	188	0.023
muscle tissue morphogenesis	GO:0060415	53	0.023
sensory organ morphogenesis	GO:0090596	242	0.023
pallium development	GO:0021543	120	0.023
superoxide metabolic process	GO:0006801	27	0.023
digestive tract development	GO:0048565	190	0.023
antimicrobial peptide secretion	GO:0002776	1	0.022
regulation of cell substrate adhesion	GO:0010810	73	0.022
limb development	GO:0060173	166	0.022
cellular response to oxygen radical	GO:0071450	14	0.022
regulation of proteolysis	GO:0030162	164	0.022
tissue homeostasis	GO:0001894	115	0.022
regulation of cartilage development	GO:0061035	44	0.022
trabecula formation	GO:0060343	24	0.021
odontogenesis	GO:0042476	78	0.021
cellular ketone metabolic process	GO:0042180	84	0.021
regulation of organ morphogenesis	GO:2000027	144	0.021
leukocyte migration	GO:0050900	124	0.021
carbohydrate metabolic process	GO:0005975	230	0.021
cation transport	GO:0006812	399	0.021
regulation of defense response	GO:0031347	233	0.020
regulation of cell motility	GO:2000145	236	0.020
protein oligomerization	GO:0051259	67	0.020
regulation of bmp signaling pathway	GO:0030510	60	0.020
regulation of rho protein signal transduction	GO:0035023	71	0.020
regulation of cellular ketone metabolic process	GO:0010565	66	0.020
oocyte axis specification	GO:0007309	2	0.020
response to peptide	GO:1901652	136	0.020
smoothened signaling pathway	GO:0007224	105	0.020
aminoglycan metabolic process	GO:0006022	34	0.020
female gonad development	GO:0008585	71	0.020
cellular component assembly involved in morphogenesis	GO:0010927	139	0.020
action potential	GO:0001508	78	0.020
heparin metabolic process	GO:0030202	3	0.020
compound eye development	GO:0048749	1	0.019
negative regulation of molecular function	GO:0044092	258	0.019
response to reactive oxygen species	GO:0000302	56	0.019
stem cell differentiation	GO:0048863	268	0.019
transmembrane transport	GO:0055085	412	0.019
regulation of homeostatic process	GO:0032844	182	0.019
smooth muscle contraction	GO:0006939	44	0.019
ensheathment of neurons	GO:0007272	76	0.019
tissue remodeling	GO:0048771	102	0.019
insulin processing	GO:0030070	2	0.019
regulation of epithelial cell proliferation	GO:0050678	141	0.018
regulation of cell adhesion	GO:0030155	154	0.018
regulation of peptidase activity	GO:0052547	96	0.018
negative regulation of protein maturation	GO:1903318	79	0.018
neuron projection guidance	GO:0097485	141	0.018
embryonic skeletal system morphogenesis	GO:0048704	91	0.018
endochondral bone growth	GO:0003416	19	0.018
regulation of mapk cascade	GO:0043408	248	0.018
positive regulation of cellular amine metabolic process	GO:0033240	5	0.018
male gamete generation	GO:0048232	285	0.018
sensory perception of mechanical stimulus	GO:0050954	107	0.018
kidney morphogenesis	GO:0060993	83	0.018
single organism cell adhesion	GO:0098602	156	0.018
epithelial tube morphogenesis	GO:0060562	303	0.018
positive regulation of cell substrate adhesion	GO:0010811	47	0.017
positive regulation of protein transport	GO:0051222	93	0.017
development of primary sexual characteristics	GO:0045137	143	0.017
regulation of bone mineralization	GO:0030500	31	0.017
striated muscle tissue development	GO:0014706	293	0.017
placenta development	GO:0001890	140	0.017
face morphogenesis	GO:0060325	29	0.017
regulation of muscle tissue development	GO:1901861	97	0.017
regulation of protein transport	GO:0051223	163	0.017
palate development	GO:0060021	76	0.017
regulation of cell migration	GO:0030334	219	0.017
heparan sulfate proteoglycan metabolic process	GO:0030201	10	0.017
blood vessel morphogenesis	GO:0048514	285	0.017
regulation of neuron differentiation	GO:0045664	281	0.016
oocyte construction	GO:0007308	2	0.016
myeloid leukocyte migration	GO:0097529	57	0.016
negative regulation of cell proliferation	GO:0008285	296	0.016
regulation of chondrocyte differentiation	GO:0032330	33	0.016
glucose metabolic process	GO:0006006	92	0.016
ras protein signal transduction	GO:0007265	77	0.016
nephron tubule morphogenesis	GO:0072078	68	0.016
development of primary female sexual characteristics	GO:0046545	73	0.016
fat cell differentiation	GO:0045444	160	0.016
response to peptide hormone	GO:0043434	127	0.016
regulation of kinase activity	GO:0043549	249	0.016
positive regulation of cytokine production	GO:0001819	174	0.016
tendon formation	GO:0035992	4	0.016
amine metabolic process	GO:0009308	45	0.016
regulation of tooth mineralization	GO:0070170	2	0.016
cellular response to peptide hormone stimulus	GO:0071375	92	0.016
angiogenesis	GO:0001525	201	0.016
regulation of membrane potential	GO:0042391	192	0.016
cardiac muscle cell proliferation	GO:0060038	31	0.015
positive regulation of kinase activity	GO:0033674	155	0.015
hormone secretion	GO:0046879	128	0.015
positive regulation of homeostatic process	GO:0032846	64	0.015
hormone metabolic process	GO:0042445	86	0.015
anatomical structure maturation	GO:0071695	49	0.015
gliogenesis	GO:0042063	141	0.015
protein localization to organelle	GO:0033365	185	0.015
blood circulation	GO:0008015	195	0.015
multicellular organismal signaling	GO:0035637	91	0.015
mesonephric tubule morphogenesis	GO:0072171	63	0.015
nephron development	GO:0072006	109	0.015
antibacterial peptide secretion	GO:0002779	1	0.015
bone mineralization	GO:0030282	54	0.015
cellular amino acid metabolic process	GO:0006520	103	0.015
regulation of organelle organization	GO:0033043	289	0.015
cardiac muscle tissue growth	GO:0055017	37	0.015
positive regulation of cellular component biogenesis	GO:0044089	94	0.014
gland development	GO:0048732	330	0.014
antibacterial peptide production	GO:0002778	2	0.014
central nervous system neuron differentiation	GO:0021953	162	0.014
regulation of blood pressure	GO:0008217	93	0.014
negative regulation of intracellular signal transduction	GO:1902532	167	0.014
regulation of establishment of protein localization	GO:0070201	181	0.014
negative regulation of bmp signaling pathway	GO:0030514	35	0.014
carbohydrate biosynthetic process	GO:0016051	74	0.014
positive regulation of bmp signaling pathway	GO:0030513	23	0.014
cardiac right ventricle formation	GO:0003219	3	0.014
face development	GO:0060324	38	0.014
organelle assembly	GO:0070925	177	0.014
positive regulation of phospholipase activity	GO:0010518	3	0.014
ear morphogenesis	GO:0042471	118	0.014
camera type eye development	GO:0043010	266	0.014
positive regulation of neuron projection development	GO:0010976	79	0.014
multicellular organismal metabolic process	GO:0044236	28	0.014
regulation of monocyte chemotaxis	GO:0090025	3	0.014
replacement ossification	GO:0036075	26	0.014
gonad development	GO:0008406	141	0.013
cellular lipid metabolic process	GO:0044255	323	0.013
negative regulation of cellular component organization	GO:0051129	194	0.013
peptide secretion	GO:0002790	114	0.013
regulation of cellular response to oxidative stress	GO:1900407	19	0.013
antimicrobial peptide biosynthetic process	GO:0002777	2	0.013
cell recognition	GO:0008037	83	0.013
positive regulation of programmed cell death	GO:0043068	218	0.013
cellular response to organic cyclic compound	GO:0071407	87	0.013
lateral inhibition	GO:0046331	1	0.013
cellular response to oxidative stress	GO:0034599	76	0.013
heart growth	GO:0060419	45	0.013
negative regulation of prostatic bud formation	GO:0060686	4	0.013
regulation of wnt signaling pathway	GO:0030111	123	0.013
skin morphogenesis	GO:0043589	38	0.013
amide transport	GO:0042886	138	0.013
response to decreased oxygen levels	GO:0036293	59	0.013
hexose metabolic process	GO:0019318	98	0.013
histone modification	GO:0016570	159	0.013
epithelial cell proliferation	GO:0050673	174	0.013
organelle fission	GO:0048285	170	0.013
renal tubule morphogenesis	GO:0061333	72	0.013
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090100	43	0.013
production of molecular mediator of immune response	GO:0002440	103	0.013
negative regulation of macrophage chemotaxis	GO:0010760	1	0.013
metanephros development	GO:0001656	79	0.013
neuronal action potential	GO:0019228	54	0.013
cytoplasmic transport	GO:0016482	234	0.013
cardiac ventricle morphogenesis	GO:0003208	50	0.013
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.013
metal ion homeostasis	GO:0055065	189	0.012
microtubule based process	GO:0007017	236	0.012
collagen fibril organization	GO:0030199	32	0.012
fatty acid metabolic process	GO:0006631	121	0.012
regulation of fat cell differentiation	GO:0045598	81	0.012
carbohydrate homeostasis	GO:0033500	128	0.012
sequestering of calcium ion	GO:0051208	18	0.012
forebrain development	GO:0030900	302	0.012
glycosaminoglycan metabolic process	GO:0030203	34	0.012
negative regulation of tooth mineralization	GO:0070171	1	0.012
regulation of tissue remodeling	GO:0034103	38	0.012
cellular response to inorganic substance	GO:0071241	37	0.012
maintenance of location	GO:0051235	89	0.012
nucleoside catabolic process	GO:0009164	206	0.012
cardiac ventricle development	GO:0003231	83	0.012
regulation of protein localization	GO:0032880	231	0.012
nephron epithelium morphogenesis	GO:0072088	68	0.012
cellular response to thyroid hormone stimulus	GO:0097067	1	0.012
positive regulation of transferase activity	GO:0051347	167	0.012
response to radiation	GO:0009314	165	0.012
negative regulation of protein processing	GO:0010955	79	0.012
leukocyte chemotaxis	GO:0030595	69	0.012
cellular response to cytokine stimulus	GO:0071345	189	0.012
actin cytoskeleton organization	GO:0030036	220	0.012
nucleosome positioning	GO:0016584	4	0.012
protein homooligomerization	GO:0051260	43	0.012
cellular response to bmp stimulus	GO:0071773	14	0.012
cell growth	GO:0016049	130	0.011
negative regulation of nervous system development	GO:0051961	156	0.011
interleukin 8 secretion	GO:0072606	3	0.011
regulation of cellular amino acid metabolic process	GO:0006521	5	0.011
bone resorption	GO:0045453	38	0.011
sensory perception of sound	GO:0007605	97	0.011
nephron tubule development	GO:0072080	84	0.011
cellular lipid catabolic process	GO:0044242	52	0.011
wound healing	GO:0042060	157	0.011
chondroitin sulfate metabolic process	GO:0030204	17	0.011
eosinophil migration	GO:0072677	3	0.011
organonitrogen compound biosynthetic process	GO:1901566	192	0.011
regulation of apoptotic signaling pathway	GO:2001233	197	0.011
cardiac chamber development	GO:0003205	108	0.011
circulatory system process	GO:0003013	197	0.011
signal transduction in absence of ligand	GO:0038034	55	0.011
fertilization	GO:0009566	127	0.011
negative regulation of proteolysis	GO:0045861	74	0.011
chromatin organization	GO:0006325	206	0.011
nuclear division	GO:0000280	158	0.011
positive regulation of lymphocyte activation	GO:0051251	140	0.011
ventricular cardiac muscle tissue morphogenesis	GO:0055010	32	0.011
response to thyroid hormone	GO:0097066	2	0.011
macromolecule catabolic process	GO:0009057	281	0.011
regulation of angiogenesis	GO:0045765	81	0.011
cellular amine metabolic process	GO:0044106	44	0.011
regulation of response to wounding	GO:1903034	189	0.011
response to extracellular stimulus	GO:0009991	127	0.011
nucleoside phosphate metabolic process	GO:0006753	338	0.011
response to retinoic acid	GO:0032526	56	0.011
cell fate commitment	GO:0045165	210	0.011
positive regulation of cell death	GO:0010942	224	0.011
trabecula morphogenesis	GO:0061383	40	0.011
cardiac septum morphogenesis	GO:0060411	46	0.011
bone trabecula formation	GO:0060346	9	0.010
reactive oxygen species biosynthetic process	GO:1903409	8	0.010
regulation of map kinase activity	GO:0043405	120	0.010
regulation of leukocyte differentiation	GO:1902105	159	0.010
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.010
sensory perception	GO:0007600	245	0.010
regulation of neuron migration	GO:2001222	22	0.010
positive regulation of protein modification process	GO:0031401	299	0.010
response to hypoxia	GO:0001666	58	0.010
cell chemotaxis	GO:0060326	81	0.010
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.010
protein import into nucleus	GO:0006606	95	0.010
response to inorganic substance	GO:0010035	96	0.010
regulation of actin filament based process	GO:0032970	99	0.010

Scara3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
musculoskeletal system disease	DOID:17	0.117
disease of anatomical entity	DOID:7	0.117
myopathy	DOID:423	0.041
muscle tissue disease	DOID:66	0.041
muscular disease	DOID:0080000	0.041
nervous system disease	DOID:863	0.041
eye and adnexa disease	DOID:1492	0.041
sensory system disease	DOID:0050155	0.041
eye disease	DOID:5614	0.037
retinal degeneration	DOID:8466	0.035
retinal disease	DOID:5679	0.035
bone development disease	DOID:0080006	0.028
bone disease	DOID:0080001	0.028
connective tissue disease	DOID:65	0.028
muscular dystrophy	DOID:9884	0.011
bone remodeling disease	DOID:0080005	0.010

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