Mus musculus

0 known processes

Arhgef11

Rho guanine nucleotide exchange factor (GEF) 11

(Aliases: KIAA0380,RhoGEF,B930073M02,E130307F09,mKIAA0380,MGC90827)

Arhgef11 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cerebellar granule cell precursor tangential migrationGO:002193511.000
facial nerve structural organizationGO:0021612100.999
postganglionic parasympathetic nervous system developmentGO:002178420.998
anterior commissure morphogenesisGO:002196060.997
facial nerve developmentGO:0021561110.997
semaphorin plexin signaling pathway involved in bone trabecula morphogenesisGO:190022020.996
glossopharyngeal nerve morphogenesisGO:002161540.995
dichotomous subdivision of terminal units involved in salivary gland branchingGO:006066650.994
trigeminal nerve morphogenesisGO:002163660.992
facial nerve morphogenesisGO:0021610110.989
negative regulation of axon guidanceGO:190266880.985
chemorepulsion of branchiomotor axonGO:002179310.982
branchiomotor neuron axon guidanceGO:002178570.980
vagus nerve developmentGO:002156430.978
semaphorin plexin signaling pathwayGO:0071526210.975
negative regulation of axon extensionGO:0030517190.974
central nervous system projection neuron axonogenesisGO:0021952210.973
negative regulation of osteoblast proliferationGO:003368940.971
semaphorin plexin signaling pathway involved in neuron projection guidanceGO:190228560.969
ossification involved in bone maturationGO:0043931120.967
branching involved in salivary gland morphogenesisGO:0060445260.964
negative chemotaxisGO:0050919140.960
trigeminal nerve structural organizationGO:002163760.955
semaphorin plexin signaling pathway involved in axon guidanceGO:190228760.954
positive regulation of rho gtpase activityGO:0032321410.952
anatomical structure arrangementGO:0048532200.945
hindbrain tangential cell migrationGO:002193420.939
regulation of rho gtpase activityGO:0032319580.936
trigeminal nerve developmentGO:0021559100.900
centrosome localizationGO:0051642130.896
ras protein signal transductionGO:0007265770.889
Human
rho protein signal transductionGO:0007266320.885
Human
central nervous system neuron axonogenesisGO:0021955280.884
limb bud formationGO:0060174100.882
negative regulation of cell projection organizationGO:0031345560.881
gtp catabolic processGO:00061841430.865
smooth muscle cell migrationGO:0014909100.863
regulation of ras gtpase activityGO:0032318880.851
cranial nerve structural organizationGO:0021604130.842
guanosine containing compound metabolic processGO:19010681440.837
regulation of negative chemotaxisGO:005092310.828
vagus nerve morphogenesisGO:002164420.822
regulation of gtp catabolic processGO:00331241130.818
positive regulation of gtp catabolic processGO:0033126850.814
guanosine containing compound catabolic processGO:19010691440.807
gtp metabolic processGO:00460391440.806
positive regulation of gtpase activityGO:0043547850.804
positive regulation of ras gtpase activityGO:0032320650.802
dichotomous subdivision of an epithelial terminal unitGO:0060600110.792
stem cell proliferationGO:00720891170.785
tube closureGO:0060606910.776
salivary gland developmentGO:0007431370.776
skeletal system developmentGO:00015013560.775
regulation of smooth muscle cell migrationGO:001491060.764
negative regulation of chemotaxisGO:0050922110.761
regulation of axon extensionGO:0030516430.752
motor neuron axon guidanceGO:0008045260.752
muscle cell migrationGO:0014812190.746
nucleoside triphosphate metabolic processGO:00091412300.746
anatomical structure maturationGO:0071695490.743
regulation of rho protein signal transductionGO:0035023710.733
negative regulation of cell morphogenesis involved in differentiationGO:0010771480.718
pyramidal neuron developmentGO:002186080.716
small gtpase mediated signal transductionGO:0007264970.715
Human
ribose phosphate metabolic processGO:00196932910.711
bone maturationGO:0070977130.709
appendage morphogenesisGO:00351071490.708
neural tube developmentGO:00219151600.708
morphogenesis of embryonic epitheliumGO:00163311590.707
regulation of neuron migrationGO:2001222220.706
negative regulation of behaviorGO:0048521140.704
organ maturationGO:0048799170.704
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.703
ribonucleoside triphosphate catabolic processGO:00092031990.698
parasympathetic nervous system developmentGO:0048486190.679
positive regulation of cytoskeleton organizationGO:0051495490.675
regulation of osteoblast proliferationGO:0033688150.670
forebrain neuron developmentGO:0021884300.668
phosphatidylinositol 3 kinase signalingGO:0014065360.665
negative regulation of neuron projection developmentGO:0010977500.662
regulation of cellular catabolic processGO:00313292420.661
neuron projection extensionGO:1990138640.660
purine ribonucleoside triphosphate catabolic processGO:00092071990.658
sympathetic nervous system developmentGO:0048485220.657
embryonic epithelial tube formationGO:00018381300.655
regulation of ras protein signal transductionGO:00465781140.650
organophosphate catabolic processGO:00464342320.648
bone trabecula morphogenesisGO:0061430120.645
purine nucleotide metabolic processGO:00061633020.645
regulation of nucleoside metabolic processGO:00091181300.642
tube formationGO:00351481400.642
neural tube closureGO:0001843900.641
limb developmentGO:00601731660.639
neural precursor cell proliferationGO:00613511210.631
positive regulation of nucleotide catabolic processGO:0030813880.629
purine ribonucleoside metabolic processGO:00461282410.629
purine nucleoside triphosphate catabolic processGO:00091462030.626
purine nucleotide catabolic processGO:00061952110.625
hindbrain developmentGO:00309021280.625
purine ribonucleoside catabolic processGO:00461302050.624
regulation of extent of cell growthGO:0061387520.623
tissue migrationGO:0090130680.621
positive regulation of cellular catabolic processGO:00313311480.618
regulation of purine nucleotide catabolic processGO:00331211220.615
purine containing compound catabolic processGO:00725232130.613
pharyngeal system developmentGO:0060037170.613
regulation of bindingGO:00510981110.612
telencephalon developmentGO:00215371860.611
regulation of nucleotide catabolic processGO:00308111220.611
developmental growth involved in morphogenesisGO:00605601380.607
glycosyl compound metabolic processGO:19016572460.603
primary neural tube formationGO:0014020950.603
regulation of purine nucleotide metabolic processGO:19005421690.602
regulation of nucleotide metabolic processGO:00061401690.601
nucleotide catabolic processGO:00091662170.600
purine nucleoside triphosphate metabolic processGO:00091442260.600
neuron projection extension involved in neuron projection guidanceGO:1902284140.598
purine ribonucleoside triphosphate metabolic processGO:00092052200.588
forebrain neuron differentiationGO:0021879520.585
negative regulation of cell developmentGO:00107211690.585
appendage developmentGO:00487361660.584
central nervous system neuron developmentGO:0021954670.584
purine ribonucleotide metabolic processGO:00091502900.582
heterocycle catabolic processGO:00467002800.577
glycosyl compound catabolic processGO:19016582060.574
cranial nerve developmentGO:0021545410.573
positive regulation of bindingGO:0051099490.572
somite developmentGO:0061053810.570
negative regulation of cell growthGO:0030308440.569
nucleoside triphosphate catabolic processGO:00091432050.565
positive regulation of neuron projection developmentGO:0010976790.563
osteoblast proliferationGO:0033687180.563
positive regulation of nucleoside metabolic processGO:0045979910.561
regulation of cell sizeGO:0008361720.560
organic cyclic compound catabolic processGO:19013612950.554
epithelial tube morphogenesisGO:00605623030.550
ribonucleoside triphosphate metabolic processGO:00091992200.546
cell migration in hindbrainGO:0021535160.543
purine ribonucleotide catabolic processGO:00091542080.542
positive regulation of nucleotide metabolic processGO:00459811140.529
nucleoside metabolic processGO:00091162460.528
purine nucleoside catabolic processGO:00061522050.527
ribonucleoside metabolic processGO:00091192450.525
regulation of cell morphogenesis involved in differentiationGO:00107691510.524
cellular nitrogen compound catabolic processGO:00442702800.515
regulation of protein bindingGO:0043393600.514
nucleoside catabolic processGO:00091642060.513
negative regulation of neuron differentiationGO:00456651010.511
cranial nerve morphogenesisGO:0021602260.510
ribonucleotide catabolic processGO:00092612080.509
positive regulation of purine nucleotide catabolic processGO:0033123880.504
phosphatidylinositol mediated signalingGO:0048015410.503
hippocampus developmentGO:0021766520.503
organonitrogen compound catabolic processGO:19015652640.499
purine nucleoside metabolic processGO:00422782410.496
nucleobase containing small molecule metabolic processGO:00550863520.493
regulation of axon guidanceGO:1902667130.490
epithelial tube formationGO:00721751300.487
regionalizationGO:00030023370.485
regulation of cellular component sizeGO:00325351210.485
blood vessel morphogenesisGO:00485142850.484
outflow tract morphogenesisGO:0003151530.482
regulation of chemotaxisGO:0050920530.481
purine containing compound metabolic processGO:00725213110.479
axon guidanceGO:00074111410.469
autonomic nervous system developmentGO:0048483430.465
regulation of neuron projection developmentGO:00109751690.464
somitogenesisGO:0001756690.463
regulation of vasculature developmentGO:1901342880.461
ribonucleoside catabolic processGO:00424542060.458
carbohydrate derivative catabolic processGO:19011362310.457
positive regulation of neuron differentiationGO:00456661410.457
positive regulation of hydrolase activityGO:00513451480.454
negative regulation of cellular component organizationGO:00511291940.452
epithelial cell migrationGO:0010631630.452
morphogenesis of a branching epitheliumGO:00611381930.451
nucleotide metabolic processGO:00091173320.448
ribonucleotide metabolic processGO:00092592910.448
negative regulation of growthGO:0045926990.445
limbic system developmentGO:0021761720.442
nucleoside phosphate metabolic processGO:00067533380.441
positive regulation of organelle organizationGO:00106381280.436
negative regulation of nervous system developmentGO:00519611560.436
central nervous system neuron differentiationGO:00219531620.431
axon extension involved in axon guidanceGO:0048846140.420
organelle localizationGO:00516401790.419
epithelium migrationGO:0090132630.419
positive regulation of phosphatidylinositol 3 kinase signalingGO:0014068200.418
aromatic compound catabolic processGO:00194392860.412
inositol lipid mediated signalingGO:0048017410.412
regulation of phosphatidylinositol 3 kinase signalingGO:0014066300.411
regulation of cell projection organizationGO:00313442060.411
regulation of neuron differentiationGO:00456642810.408
ossificationGO:00015032160.407
pyramidal neuron differentiationGO:002185990.406
forebrain developmentGO:00309003020.405
pallium developmentGO:00215431200.404
regulation of cell motilityGO:20001452360.403
nucleoside phosphate catabolic processGO:19012922220.403
neuron migrationGO:00017641220.399
gland developmentGO:00487323300.392
axonogenesisGO:00074092740.386
regulation of cytoskeleton organizationGO:00514931220.383
positive regulation of nervous system developmentGO:00519622210.377
peripheral nervous system developmentGO:0007422530.373
heart morphogenesisGO:00030071780.367
positive regulation of cell projection organizationGO:0031346950.366
regulation of hydrolase activityGO:00513362460.363
positive regulation of cell developmentGO:00107202370.363
endothelial cell migrationGO:0043542440.361
trabecula morphogenesisGO:0061383400.359
neuroblast proliferationGO:0007405490.353
nerve developmentGO:0021675670.353
positive regulation of purine nucleotide metabolic processGO:19005441140.346
branching morphogenesis of an epithelial tubeGO:00487541590.343
forebrain generation of neuronsGO:0021872630.332
segmentationGO:0035282930.325
positive regulation of protein bindingGO:0032092290.320
cell growthGO:00160491300.313
synapse assemblyGO:0007416560.307
morphogenesis of a branching structureGO:00017632030.305
salivary gland morphogenesisGO:0007435330.297
preganglionic parasympathetic nervous system developmentGO:0021783170.294
developmental maturationGO:00217001930.293
regulation of cell growthGO:0001558910.291
glossopharyngeal nerve developmentGO:002156350.286
limb morphogenesisGO:00351081490.268
ameboidal type cell migrationGO:00016671280.260
negative regulation of cell proliferationGO:00082852960.258
neuron projection guidanceGO:00974851410.246
developmental cell growthGO:0048588840.246
chemotaxisGO:00069352470.240
regulation of cell shapeGO:0008360390.234
regulation of cell migrationGO:00303342190.219
regulation of organelle organizationGO:00330432890.201
angiogenesisGO:00015252010.148
negative regulation of cell adhesionGO:0007162450.132
regulation of angiogenesisGO:0045765810.132
cell adhesionGO:00071553290.128
regulation of cell adhesionGO:00301551540.118
regulation of anatomical structure sizeGO:00900661780.087
synapse organizationGO:00508081250.082
exocrine system developmentGO:0035272450.066
neural tube formationGO:00018411080.059
negative regulation of molecular functionGO:00440922580.046
g protein coupled receptor signaling pathwayGO:00071862430.042
Human
bone developmentGO:00603481200.039
positive regulation of cellular amino acid metabolic processGO:004576430.037
negative regulation of phosphate metabolic processGO:00459361840.037
actin cytoskeleton organizationGO:00300362200.035
regulation of cellular amino acid metabolic processGO:000652150.034
negative regulation of phosphorus metabolic processGO:00105631840.033
cellular amino acid metabolic processGO:00065201030.031
amine metabolic processGO:0009308450.030
epithelial cell proliferationGO:00506731740.029
multicellular organismal signalingGO:0035637910.028
sensory perceptionGO:00076002450.027
macromolecule catabolic processGO:00090572810.027
regulation of cellular amine metabolic processGO:0033238200.025
positive regulation of cellular amine metabolic processGO:003324050.024
inorganic cation transmembrane transportGO:00986622070.024
negative regulation of nucleotide catabolic processGO:003081290.024
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.022
protein modification by small protein conjugation or removalGO:00706472070.022
protein targetingGO:00066051430.021
cell chemotaxisGO:0060326810.020
regulation of secretionGO:00510462740.020
positive regulation of cell deathGO:00109422240.020
posttranscriptional regulation of gene expressionGO:00106081550.019
regulation of cell cycleGO:00517262810.019
response to growth factorGO:00708481980.018
cellular ketone metabolic processGO:0042180840.018
regulation of epithelial cell proliferationGO:00506781410.018
protein modification by small protein conjugationGO:00324461870.018
negative regulation of purine nucleotide catabolic processGO:003312290.018
cation transmembrane transportGO:00986552660.018
cellular response to dna damage stimulusGO:00069742070.018
intracellular protein transportGO:00068862040.017
protein localization to organelleGO:00333651850.017
methylationGO:00322591340.017
leukocyte differentiationGO:00025213420.017
immune effector processGO:00022523210.016
regulation of cellular ketone metabolic processGO:0010565660.016
cellular response to organonitrogen compoundGO:00714171450.016
inorganic ion transmembrane transportGO:00986602340.016
regulation of cell activationGO:00508652890.016
chromatin organizationGO:00063252060.016
cellular macromolecule catabolic processGO:00442652060.016
inflammatory responseGO:00069542440.016
transmembrane transportGO:00550854120.015
germ cell developmentGO:00072811850.015
neuronal action potentialGO:0019228540.015
reactive oxygen species metabolic processGO:0072593840.015
apoptotic signaling pathwayGO:00971903060.015
actin filament organizationGO:00070151130.015
negative regulation of purine nucleotide metabolic processGO:1900543160.015
positive regulation of protein modification processGO:00314012990.015
regulation of secretion by cellGO:19035302490.014
actin filament based movementGO:0030048230.014
stem cell differentiationGO:00488632680.014
response to organonitrogen compoundGO:00102432460.014
negative regulation of cell motilityGO:2000146610.014
retrograde transport endosome to golgiGO:004214720.014
respiratory system developmentGO:00605411900.014
negative regulation of immune system processGO:00026832090.014
positive regulation of mapk cascadeGO:00434101700.014
carbohydrate derivative biosynthetic processGO:19011371830.014
cellular response to hormone stimulusGO:00328701500.014
positive regulation of protein phosphorylationGO:00019342420.014
oxidation reduction processGO:00551143420.014
endothelial cell proliferationGO:0001935270.014
dna metabolic processGO:00062593030.013
microtubule cytoskeleton organizationGO:00002261570.013
regulation of mitotic cell cycleGO:00073461260.013
negative regulation of cell activationGO:00508661110.013
compound eye developmentGO:004874910.013
regulation of cellular component biogenesisGO:00440871810.013
mitotic cell cycleGO:00002781950.013
cellular amine metabolic processGO:0044106440.013
cellular chemical homeostasisGO:00550822150.013
chromatin modificationGO:00165681870.013
organelle fissionGO:00482851700.013
negative regulation of synapse assemblyGO:005196430.013
action potentialGO:0001508780.013
negative regulation of gtpase activityGO:003426060.013
locomotory behaviorGO:00076261950.013
organonitrogen compound biosynthetic processGO:19015661920.013
dna repairGO:00062811070.013
cognitionGO:00508901490.013
sensory perception of mechanical stimulusGO:00509541070.013
cellular lipid metabolic processGO:00442553230.012
positive regulation of programmed cell deathGO:00430682180.012
negative regulation of protein metabolic processGO:00512482820.012
negative regulation of nucleotide metabolic processGO:0045980160.012
mitotic cell cycle processGO:19030471590.012
regulation of cytokine productionGO:00018172660.012
wnt signaling pathwayGO:00160551880.012
spermatogenesisGO:00072832840.012
regulation of intracellular transportGO:00323861590.012
carbohydrate metabolic processGO:00059752300.012
multicellular organismal homeostasisGO:00488711640.012
actin mediated cell contractionGO:0070252150.012
modification dependent protein catabolic processGO:00199411330.012
rab protein signal transductionGO:003248210.012
negative regulation of cellular amine metabolic processGO:003323910.012
negative regulation of hydrolase activityGO:0051346710.012
cellular response to cytokine stimulusGO:00713451890.012
endomembrane system organizationGO:00102561470.012
modification dependent macromolecule catabolic processGO:00436321330.012
myeloid cell differentiationGO:00300992330.012
single organism cell adhesionGO:00986021560.012
nucleocytoplasmic transportGO:00069131390.011
regulation of embryonic developmentGO:0045995710.011
positive regulation of epithelial cell proliferationGO:0050679680.011
dephosphorylationGO:00163111290.011
sprouting angiogenesisGO:0002040260.011
rhythmic processGO:00485111740.011
protein maturationGO:00516041760.011
regulation of protein kinase activityGO:00458592320.011
histone modificationGO:00165701590.011
organophosphate biosynthetic processGO:00904071220.011
protein catabolic processGO:00301632210.011
microtubule based processGO:00070172360.011
mitochondrion organizationGO:00070051340.011
response to insulinGO:00328681000.011
protein processingGO:00164851630.011
male gamete generationGO:00482322850.011
cellular homeostasisGO:00197252400.011
regulation of wnt signaling pathwayGO:00301111230.011
digestive system developmentGO:00551232000.011
ubiquitin dependent protein catabolic processGO:00065111290.011
cytokine productionGO:00018163190.011
tissue homeostasisGO:00018941150.011
regulation of kinase activityGO:00435492490.011
cell substrate adhesionGO:00315891300.011
regulation of apoptotic signaling pathwayGO:20012331970.010
spermatid differentiationGO:00485151150.010
positive chemotaxisGO:0050918180.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.010
urogenital system developmentGO:00016552610.010
regulation of proteolysisGO:00301621640.010
canonical wnt signaling pathwayGO:00600701300.010
gliogenesisGO:00420631410.010
organelle assemblyGO:00709251770.010
negative regulation of cellular protein metabolic processGO:00322692470.010
ion transmembrane transportGO:00342203610.010
ear developmentGO:00435832000.010
engulfment of apoptotic cellGO:004365230.010
regulation of synaptic growth at neuromuscular junctionGO:000858240.010
regulation of feeding behaviorGO:006025930.010
establishment of protein localization to organelleGO:00725941180.010

Arhgef11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.039
cancerDOID:16200.034
organ system cancerDOID:005068600.033
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.021
central nervous system diseaseDOID:33100.014
immune system cancerDOID:006008300.013