Mus musculus

0 known processes

Klk1b8

kallikrein 1-related peptidase b8

(Aliases: Klk8,mGK-8,Nrpn,TADG14,MGC18615)

Klk1b8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
bradykinin biosynthetic processGO:000293610.998
Mouse
tissue kallikrein kinin cascadeGO:000225510.998
Mouse
kinin cascadeGO:000225420.996
Mouse
left ventricular cardiac muscle tissue morphogenesisGO:000322020.995
Mouse
positive regulation of vasoconstrictionGO:004590740.978
Rat
protein activation cascadeGO:0072376190.977
Mouse
positive regulation of lipid kinase activityGO:0090218110.970
Mouse
negative regulation of neuron projection regenerationGO:007057130.962
Mouse
regulation of phosphatidylinositol 3 kinase activityGO:0043551140.944
Mouse
positive regulation of lipid metabolic processGO:0045834400.919
Mouse
binding of sperm to zona pellucidaGO:0007339340.915
Mouse
regulation of blood volume by renin angiotensinGO:000201670.854
Mouse
positive regulation of phosphatidylinositol 3 kinase activityGO:0043552110.819
Mouse
zymogen activationGO:0031638410.778
Mouse
regulation of lipid kinase activityGO:0043550140.763
Mouse
cell cell recognitionGO:0009988440.730
Mouse
cellular lipid metabolic processGO:00442553230.688
Mouse
sperm egg recognitionGO:0035036370.679
Mouse
keratinocyte proliferationGO:0043616210.669
Mouse
neurological system process involved in regulation of systemic arterial blood pressureGO:0001976180.647
Mouse
brain renin angiotensin systemGO:000203550.609
Mouse
inflammatory responseGO:00069542440.600
Mouse
action potentialGO:0001508780.585
cardiac muscle contractionGO:0060048320.573
Mouse
protein processingGO:00164851630.573
Mouse
muscle system processGO:00030121410.518
Mouse
peptide metabolic processGO:0006518460.502
Mouse
regulation of systemic arterial blood pressure by renin angiotensinGO:0003081200.474
Mouse
protein maturationGO:00516041760.473
Mouse
fertilizationGO:00095661270.448
Mouse
single fertilizationGO:0007338820.447
Mouse
cognitionGO:00508901490.437
Mouse
cardiac chamber developmentGO:00032051080.395
Mouse
striated muscle contractionGO:0006941450.378
Mouse
regulation of lipid metabolic processGO:00192161180.377
Mouse
phospholipid metabolic processGO:0006644870.354
Mouse
regulation of systemic arterial blood pressure by hormoneGO:0001990250.350
Mouse
regulation of transferase activityGO:00513382630.332
Mouse
regulation of blood pressureGO:0008217930.331
Mouse
muscle tissue morphogenesisGO:0060415530.318
Mouse
regulation of neuron projection regenerationGO:007057070.317
Mouse
cellular amide metabolic processGO:0043603580.308
Mouse
endocrine processGO:0050886390.293
Mouse
regulation of myelinationGO:0031641200.288
Mouse
axon ensheathmentGO:0008366760.283
Mouse
regulation of neuron differentiationGO:00456642810.280
Mouse
neuronal action potentialGO:0019228540.261
heart morphogenesisGO:00030071780.260
Mouse
learning or memoryGO:00076111480.254
Mouse
extracellular structure organizationGO:00430621480.253
Mouse
positive regulation of transferase activityGO:00513471670.251
Mouse
regulation of membrane potentialGO:00423911920.249
cardiac left ventricle morphogenesisGO:000321490.234
Mouse
regulation of blood circulationGO:1903522930.231
Rat
multicellular organismal signalingGO:0035637910.207
regulation of response to woundingGO:19030341890.200
Mouse
cardiac ventricle morphogenesisGO:0003208500.198
Mouse
cardiac muscle tissue developmentGO:00487381300.198
Mouse
cardiac ventricle developmentGO:0003231830.196
Mouse
negative regulation of nervous system developmentGO:00519611560.195
Mouse
regulation of neuron projection developmentGO:00109751690.193
Mouse
cardiac chamber morphogenesisGO:0003206930.193
Mouse
small gtpase mediated signal transductionGO:0007264970.192
Mouse
cardiac muscle tissue morphogenesisGO:0055008440.185
Mouse
regulation of systemic arterial blood pressureGO:0003073610.185
Mouse
acute inflammatory responseGO:0002526410.183
Mouse
muscle tissue developmentGO:00605373080.181
Mouse
macromolecule catabolic processGO:00090572810.177
Mouse
regulation of tube sizeGO:0035150570.173
Mouse Rat
positive regulation of kinase activityGO:00336741550.171
Mouse
blood circulationGO:00080151950.165
Mouse Rat
oxidation reduction processGO:00551143420.164
regulation of cellular response to stressGO:00801351590.164
Mouse
muscle contractionGO:00069361010.159
Mouse
synapse organizationGO:00508081250.155
Mouse
vasoconstrictionGO:0042310270.151
Rat
positive regulation of blood circulationGO:1903524220.149
Rat
organonitrogen compound biosynthetic processGO:19015661920.146
Mouse
vasodilationGO:0042311280.143
Mouse
ensheathment of neuronsGO:0007272760.138
Mouse
cellular response to insulin stimulusGO:0032869780.136
myelinationGO:0042552740.127
Mouse
regulation of cell projection organizationGO:00313442060.121
Mouse
regulation of neurological system processGO:0031644220.121
Mouse
peptide biosynthetic processGO:0043043110.121
Mouse
negative regulation of cell developmentGO:00107211690.121
Mouse
circulatory system processGO:00030131970.120
Mouse Rat
neuron projection regenerationGO:0031102140.117
Mouse
cell recognitionGO:0008037830.117
Mouse
heart contractionGO:0060047930.116
Mouse
protein catabolic processGO:00301632210.114
Mouse
transmission of nerve impulseGO:0019226760.114
extracellular matrix organizationGO:00301981470.109
Mouse
regulation of vasoconstrictionGO:0019229140.109
Rat
axon regenerationGO:0031103120.105
Mouse
epithelial cell proliferationGO:00506731740.102
Mouse
negative regulation of neurological system processGO:003164570.100
Mouse
negative regulation of neuron differentiationGO:00456651010.093
Mouse
negative regulation of response to woundingGO:1903035770.089
Mouse
regulation of blood vessel sizeGO:0050880560.088
Mouse Rat
negative regulation of cellular component organizationGO:00511291940.082
Mouse
heart processGO:0003015940.080
Mouse
regulation of kinase activityGO:00435492490.079
Mouse
negative regulation of neuron projection developmentGO:0010977500.078
Mouse
amine metabolic processGO:0009308450.075
ventricular cardiac muscle tissue morphogenesisGO:0055010320.073
Mouse
ventricular cardiac muscle tissue developmentGO:0003229380.072
Mouse
vascular process in circulatory systemGO:0003018620.071
Mouse Rat
multicellular organism growthGO:00352641610.071
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044330.068
Mouse
positive regulation of cellular amine metabolic processGO:003324050.068
homeostasis of number of cellsGO:00488722100.066
monosaccharide biosynthetic processGO:0046364440.065
olfactory learningGO:000835520.065
striated muscle tissue developmentGO:00147062930.065
Mouse
regulation of anatomical structure sizeGO:00900661780.064
Mouse Rat
amelogenesisGO:0097186120.063
Mouse
cellular amino acid metabolic processGO:00065201030.060
cellular response to testosterone stimulusGO:007139410.060
regulation of cellular ketone metabolic processGO:0010565660.058
mitochondrion organizationGO:00070051340.058
carbohydrate biosynthetic processGO:0016051740.057
cellular response to peptide hormone stimulusGO:0071375920.056
spermatogenesisGO:00072832840.055
gluconeogenesisGO:0006094390.054
regulation of myeloid cell differentiationGO:0045637960.054
cellular ketone metabolic processGO:0042180840.053
positive regulation of cellular amino acid metabolic processGO:004576430.052
regulation of gluconeogenesisGO:0006111300.052
cellular response to foodGO:007124010.048
lipid biosynthetic processGO:00086101790.048
myeloid cell differentiationGO:00300992330.045
carbohydrate metabolic processGO:00059752300.045
negative regulation of myelinationGO:003164260.044
Mouse
amide biosynthetic processGO:0043604160.044
Mouse
regulation of cellular amino acid metabolic processGO:000652150.044
cellular carbohydrate metabolic processGO:00442621190.044
regulation of cellular amine metabolic processGO:0033238200.042
negative regulation of cell proliferationGO:00082852960.041
alpha amino acid metabolic processGO:1901605590.039
positive regulation of programmed cell deathGO:00430682180.038
cellular amine metabolic processGO:0044106440.038
monocarboxylic acid metabolic processGO:00327871910.038
response to peptideGO:19016521360.037
negative regulation of insulin secretionGO:0046676140.036
retina development in camera type eyeGO:00600411190.036
reactive oxygen species metabolic processGO:0072593840.036
generation of precursor metabolites and energyGO:00060911030.035
skin developmentGO:00435882200.034
hexose biosynthetic processGO:0019319390.033
tissue homeostasisGO:00018941150.033
positive regulation of cell deathGO:00109422240.033
nitrogen compound transportGO:00717052710.033
epidermis developmentGO:00085441870.033
negative regulation of molecular functionGO:00440922580.032
glucose homeostasisGO:00425931280.032
regulation of carbohydrate metabolic processGO:0006109750.032
carboxylic acid biosynthetic processGO:0046394860.031
cellular response to hormone stimulusGO:00328701500.031
cellular response to organonitrogen compoundGO:00714171450.030
regulation of cellular carbohydrate metabolic processGO:0010675750.030
insulin receptor signaling pathwayGO:0008286490.029
negative regulation of protein metabolic processGO:00512482820.029
response to peptide hormoneGO:00434341270.028
digestive tract developmentGO:00485651900.028
metal ion homeostasisGO:00550651890.028
response to organonitrogen compoundGO:00102432460.027
regulation of eosinophil migrationGO:200041620.027
positive regulation of apoptotic processGO:00430652170.027
cation transportGO:00068123990.026
organic acid biosynthetic processGO:0016053860.025
cell maturationGO:00484691270.025
erythrocyte differentiationGO:0030218880.025
regulation of glucose metabolic processGO:0010906600.025
gland developmentGO:00487323300.025
regulation of synaptic growth at neuromuscular junctionGO:000858240.024
lipid localizationGO:00108761260.024
glucose metabolic processGO:0006006920.024
columnar cuboidal epithelial cell differentiationGO:0002065820.024
regenerationGO:0031099380.024
Mouse
male gamete generationGO:00482322850.024
regulation of hormone levelsGO:00108172110.023
myeloid cell homeostasisGO:00022621140.023
anatomical structure homeostasisGO:00602491450.023
single organismal cell cell adhesionGO:00163371310.023
circadian rhythmGO:00076231140.023
positive regulation of thymocyte migrationGO:200041220.023
cofactor metabolic processGO:0051186800.022
amide transportGO:00428861380.022
neutrophil mediated killing of gram positive bacteriumGO:007094620.022
multicellular organismal homeostasisGO:00488711640.022
peptide transportGO:00158331330.021
axonogenesisGO:00074092740.021
hexose metabolic processGO:0019318980.021
nucleotide metabolic processGO:00091173320.021
morphogenesis of a branching structureGO:00017632030.021
response to organic cyclic compoundGO:00140701980.021
isoprenoid metabolic processGO:0006720290.021
negative regulation of insulin secretion involved in cellular response to glucose stimulusGO:006117940.021
cellular response to external stimulusGO:0071496880.020
macromolecule glycosylationGO:0043413550.020
organic cyclic compound catabolic processGO:19013612950.020
regulation of angiotensin levels in bloodGO:000200240.020
vitamin a metabolic processGO:000677620.020
cellular response to monosaccharide stimulusGO:0071326470.020
positive regulation of protein secretionGO:0050714520.019
regulation of cytokine productionGO:00018172660.019
negative regulation of cell projection organizationGO:0031345560.019
Mouse
neural tube developmentGO:00219151600.019
cellular macromolecule catabolic processGO:00442652060.019
protein glycosylationGO:0006486550.019
peptide hormone secretionGO:00300721090.019
reactive nitrogen species metabolic processGO:200105700.019
cellular response to peptideGO:1901653920.019
cellular ion homeostasisGO:00068731650.019
reactive oxygen species biosynthetic processGO:190340980.019
cell type specific apoptotic processGO:00972852680.019
cellular response to organic cyclic compoundGO:0071407870.019
catecholamine uptakeGO:009049340.019
granzyme mediated apoptotic signaling pathwayGO:000862610.018
sensory perceptionGO:00076002450.018
learningGO:0007612980.018
protein modification by small protein conjugation or removalGO:00706472070.018
spermatid differentiationGO:00485151150.018
carboxylic acid catabolic processGO:0046395510.018
dephosphorylationGO:00163111290.018
regulation of phospholipase c activityGO:190027430.018
cellular chemical homeostasisGO:00550822150.018
maintenance of locationGO:0051235890.017
peptidyl amino acid modificationGO:00181933360.017
cellular homeostasisGO:00197252400.017
germ cell developmentGO:00072811850.017
negative regulation of peptide hormone secretionGO:0090278160.017
negative regulation of phosphorylationGO:00423261660.017
glycosylationGO:0070085620.017
positive regulation of organelle organizationGO:00106381280.017
digestive system developmentGO:00551232000.017
purine containing compound metabolic processGO:00725213110.017
regulation of hydrolase activityGO:00513362460.017
positive regulation of phospholipase activityGO:001051830.017
response to decreased oxygen levelsGO:0036293590.016
negative regulation of protein modification processGO:00314001630.016
cellularizationGO:000734910.016
cellular glucose homeostasisGO:0001678520.016
development of primary sexual characteristicsGO:00451371430.016
single organism cell adhesionGO:00986021560.016
defense response to bacteriumGO:00427421190.016
negative regulation of intracellular signal transductionGO:19025321670.015
endothelial cell differentiationGO:0045446410.015
response to insulinGO:00328681000.015
regulation of vitamin metabolic processGO:003065630.015
response to nutrient levelsGO:00316671090.015
response to oxygen levelsGO:0070482620.015
cell adhesionGO:00071553290.015
visual perceptionGO:0007601520.015
epithelial cell developmentGO:00020641590.015
regulation of secretion by cellGO:19035302490.015
negative regulation of cellular protein metabolic processGO:00322692470.015
response to acid chemicalGO:00011011110.015
cellular metal ion homeostasisGO:00068751510.015
regulation of reactive oxygen species metabolic processGO:2000377400.015
protein secretionGO:00093061110.014
regulation of body fluid levelsGO:00508781620.014
response to inorganic substanceGO:0010035960.014
regulation of mapk cascadeGO:00434082480.014
defense response to other organismGO:00985421970.014
inorganic cation transmembrane transportGO:00986622070.014
carbohydrate derivative biosynthetic processGO:19011371830.014
negative regulation of phosphorus metabolic processGO:00105631840.014
positive regulation of eosinophil migrationGO:200041820.014
anion transportGO:00068201770.014
wound healingGO:00420601570.014
immune effector processGO:00022523210.014
activation of phospholipase c activityGO:000720220.014
leukocyte differentiationGO:00025213420.013
regulation of lymphocyte differentiationGO:00456191070.013
regulation of t cell differentiationGO:0045580830.013
defense response to gram positive bacteriumGO:0050830500.013
monosaccharide metabolic processGO:00059961060.013
leukocyte proliferationGO:00706611720.013
odontogenesisGO:0042476780.013
Mouse
regulation of isoprenoid metabolic processGO:001974710.013
purine nucleotide metabolic processGO:00061633020.013
terpenoid metabolic processGO:0006721250.013
retinoid metabolic processGO:0001523240.013
sequestering of calcium ionGO:0051208180.013
regulation of cellular component biogenesisGO:00440871810.013
response to oxidative stressGO:00069791230.013
cation homeostasisGO:00550802120.013
regulation of system processGO:00440572000.013
Mouse Rat
heterocycle catabolic processGO:00467002800.013
organelle fissionGO:00482851700.013
cellular response to carbohydrate stimulusGO:0071322500.013
negative regulation of leukocyte differentiationGO:1902106510.013
cation transmembrane transportGO:00986552660.013
response to monosaccharideGO:0034284670.012
regulation of epithelial cell proliferationGO:00506781410.012
cellular divalent inorganic cation homeostasisGO:00725031270.012
regulation of inward rectifier potassium channel activityGO:190197910.012
cellular response to biotic stimulusGO:0071216920.012
renal system developmentGO:00720012250.012
eosinophil migrationGO:007267730.012
chromatin organizationGO:00063252060.012
response to lipopolysaccharideGO:00324961280.012
t cell differentiationGO:00302171740.012
branching morphogenesis of an epithelial tubeGO:00487541590.012
hormone secretionGO:00468791280.012
leukocyte homeostasisGO:0001776790.012
placenta developmentGO:00018901400.012
organic hydroxy compound metabolic processGO:19016152030.012
cellular respirationGO:0045333380.012
epithalamus developmentGO:002153820.012
regulation of carbohydrate biosynthetic processGO:0043255400.012
positive regulation of thyroid hormone generationGO:200061120.012
apoptotic signaling pathwayGO:00971903060.012
blood vessel morphogenesisGO:00485142850.012
glycoprotein metabolic processGO:00091001160.012
nucleobase containing small molecule metabolic processGO:00550863520.012
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
lymphocyte mediated immunityGO:00024491390.011
peptide secretionGO:00027901140.011
positive regulation of protein modification processGO:00314012990.011
insulin secretionGO:0030073890.011
cellular potassium ion transportGO:0071804430.011
energy reserve metabolic processGO:0006112390.011
dibenzo p dioxin metabolic processGO:001889410.011
negative regulation of immune effector processGO:0002698550.011
thymocyte migrationGO:007267920.011
positive regulation of phospholipase c activityGO:001086320.011
cellular response to lipidGO:00713961450.011
positive regulation of keratinocyte proliferationGO:001083840.011
retinal blood vessel morphogenesisGO:006130430.011
negative regulation of peptide secretionGO:0002792160.011
purine ribonucleoside metabolic processGO:00461282410.011
positive regulation of cell developmentGO:00107202370.011
rho protein signal transductionGO:0007266320.011
stem cell proliferationGO:00720891170.011
drug metabolic processGO:001714440.011
cellular modified amino acid metabolic processGO:0006575630.011
protein modification by small protein conjugationGO:00324461870.011
monocarboxylic acid biosynthetic processGO:0072330610.011
divalent metal ion transportGO:00708381720.011
viral gene expressionGO:001908030.011
protein acylationGO:0043543640.011
wnt signaling pathwayGO:00160551880.011
sperm motilityGO:0030317470.011
mast cell proliferationGO:007066240.011
calcium mediated signalingGO:0019722460.010
ribonucleotide metabolic processGO:00092592910.010
calcium ion homeostasisGO:00550741270.010
regulation of proteolysisGO:00301621640.010
regulation of leukocyte differentiationGO:19021051590.010
energy derivation by oxidation of organic compoundsGO:0015980770.010
activation of mapk activity involved in innate immune responseGO:003541920.010
regulation of organelle organizationGO:00330432890.010
digestionGO:0007586400.010

Klk1b8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.017
disease of anatomical entityDOID:700.017
neurodegenerative diseaseDOID:128900.017
central nervous system diseaseDOID:33100.017
bone diseaseDOID:008000100.011
connective tissue diseaseDOID:6500.011
musculoskeletal system diseaseDOID:1700.011