Mus musculus

82 known processes

Aifm1

apoptosis-inducing factor, mitochondrion-associated 1

(Aliases: Hq,mAIF,Pdcd8,MGC5706,AIF,AIFsh2)

Aifm1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular hyperosmotic salinity responseGO:007147501.000
oxidation reduction processGO:00551143420.798
cellular response to salt stressGO:007147210.777
mitochondrion organizationGO:00070051340.712
coenzyme metabolic processGO:0006732520.506
mitochondrial respiratory chain complex assemblyGO:003310820.418
mitochondrial translationGO:003254340.350
generation of precursor metabolites and energyGO:00060911030.346
Fly
energy derivation by oxidation of organic compoundsGO:0015980770.326
Fly
cellular respirationGO:0045333380.235
Fly
acetyl coa biosynthetic processGO:000608550.220
hyperosmotic salinity responseGO:004253810.205
cellular hyperosmotic responseGO:007147400.199
mitochondrial transportGO:0006839360.148
glycosyl compound metabolic processGO:19016572460.139
Fly
cofactor biosynthetic processGO:0051188410.136
macromolecule catabolic processGO:00090572810.133
acetyl coa biosynthetic process from pyruvateGO:000608630.132
regulation of membrane potentialGO:00423911920.129
regulation of peptidase activityGO:0052547960.128
negative regulation of cellular response to oxidative stressGO:1900408100.127
transmembrane transportGO:00550854120.112
cellular amino acid metabolic processGO:00065201030.110
purine nucleoside metabolic processGO:00422782410.107
Fly
cellular ketone metabolic processGO:0042180840.105
coenzyme biosynthetic processGO:0009108230.103
translationGO:0006412930.102
organic acid catabolic processGO:0016054510.099
citrate metabolic processGO:000610130.098
monocarboxylic acid metabolic processGO:00327871910.097
purine ribonucleotide metabolic processGO:00091502900.095
Fly
small molecule catabolic processGO:0044282710.094
cofactor metabolic processGO:0051186800.093
response to oxygen radicalGO:0000305160.090
regulation of cellular ketone metabolic processGO:0010565660.089
protein processingGO:00164851630.087
cellular lipid metabolic processGO:00442553230.085
thioester metabolic processGO:0035383190.084
gland developmentGO:00487323300.082
cellular nitrogen compound catabolic processGO:00442702800.081
response to organic cyclic compoundGO:00140701980.078
multicellular organism growthGO:00352641610.078
protein maturationGO:00516041760.078
nucleoside phosphate metabolic processGO:00067533380.075
Fly
nitrogen compound transportGO:00717052710.075
apoptotic signaling pathwayGO:00971903060.074
negative regulation of apoptotic signaling pathwayGO:20012341040.071
neuron apoptotic processGO:00514021420.071
negative regulation of immune system processGO:00026832090.070
acyl coa biosynthetic processGO:007161670.069
endomembrane system organizationGO:00102561470.069
kidney developmentGO:00018222130.067
multicellular organismal homeostasisGO:00488711640.065
response to inorganic substanceGO:0010035960.064
regulation of cellular catabolic processGO:00313292420.063
cristae formationGO:004240730.063
amine metabolic processGO:0009308450.062
protein localization to organelleGO:00333651850.059
myeloid cell differentiationGO:00300992330.058
response to ionizing radiationGO:0010212420.058
cellular response to oxidative stressGO:0034599760.058
hyperosmotic responseGO:000697240.056
response to oxidative stressGO:00069791230.056
purine ribonucleoside metabolic processGO:00461282410.056
Fly
response to steroid hormoneGO:0048545560.056
protein oxidationGO:001815820.056
cellular macromolecule catabolic processGO:00442652060.055
organic cyclic compound catabolic processGO:19013612950.054
regulation of cellular amino acid metabolic processGO:000652150.054
thioester biosynthetic processGO:003538470.053
male gamete generationGO:00482322850.052
fatty acid oxidationGO:0019395280.051
cellular protein complex assemblyGO:00436231160.050
reactive oxygen species metabolic processGO:0072593840.049
organic hydroxy compound metabolic processGO:19016152030.049
nucleobase containing small molecule metabolic processGO:00550863520.048
Fly
spermatid developmentGO:00072861080.048
response to reactive oxygen speciesGO:0000302560.048
homeostasis of number of cellsGO:00488722100.047
cellular response to osmotic stressGO:007147070.046
cellular metal ion homeostasisGO:00068751510.046
regulation of apoptotic signaling pathwayGO:20012331970.045
positive regulation of growthGO:00459271040.044
vasodilationGO:0042311280.043
membrane organizationGO:00610242450.043
negative regulation of molecular functionGO:00440922580.042
aromatic compound catabolic processGO:00194392860.042
ion transmembrane transportGO:00342203610.042
leukocyte differentiationGO:00025213420.042
protein transmembrane transportGO:007180680.042
nucleoside monophosphate metabolic processGO:0009123850.042
Fly
ribonucleotide metabolic processGO:00092592910.041
Fly
inflammatory responseGO:00069542440.041
inner mitochondrial membrane organizationGO:000700750.041
lipid biosynthetic processGO:00086101790.040
liver developmentGO:0001889660.040
purine ribonucleoside triphosphate metabolic processGO:00092052200.039
Fly
cellular homeostasisGO:00197252400.039
lipid oxidationGO:0034440290.036
intrinsic apoptotic signaling pathwayGO:00971931320.036
cellular response to lipidGO:00713961450.035
blood circulationGO:00080151950.035
organonitrogen compound biosynthetic processGO:19015661920.035
negative regulation of response to oxidative stressGO:1902883100.035
ribose phosphate metabolic processGO:00196932910.034
Fly
regulation of secretion by cellGO:19035302490.034
spermatogenesisGO:00072832840.034
heart processGO:0003015940.034
response to organonitrogen compoundGO:00102432460.034
mitochondrial protein processingGO:003498250.034
protein targeting to mitochondrionGO:000662660.034
peptidyl amino acid modificationGO:00181933360.034
dna metabolic processGO:00062593030.034
regulation of hydrolase activityGO:00513362460.034
multicellular organismal agingGO:0010259240.033
renal system developmentGO:00720012250.033
epithelial tube morphogenesisGO:00605623030.033
mitochondrion degradationGO:000042230.033
circulatory system processGO:00030131970.033
small molecule biosynthetic processGO:00442831320.033
cellular amine metabolic processGO:0044106440.032
cation homeostasisGO:00550802120.032
defecationGO:003042110.032
cellular aldehyde metabolic processGO:0006081120.032
carnitine metabolic processGO:000943770.032
iron ion homeostasisGO:0055072360.032
regulation of anatomical structure sizeGO:00900661780.031
epithelial cell developmentGO:00020641590.031
transition metal ion homeostasisGO:0055076540.031
myeloid leukocyte differentiationGO:00025731190.031
heart morphogenesisGO:00030071780.031
nucleotide metabolic processGO:00091173320.030
Fly
muscle system processGO:00030121410.030
hepaticobiliary system developmentGO:0061008670.030
atp metabolic processGO:0046034750.030
Fly
protein oligomerizationGO:0051259670.030
engulfment of apoptotic cellGO:004365230.029
anatomical structure homeostasisGO:00602491450.029
trna aminoacylationGO:004303910.029
carbohydrate metabolic processGO:00059752300.029
regulation of response to oxidative stressGO:1902882190.029
positive regulation of reactive oxygen species metabolic processGO:2000379110.028
response to superoxideGO:0000303160.028
mitochondrial membrane organizationGO:0007006260.028
endocytosisGO:00068971680.028
spermatid differentiationGO:00485151150.027
morphogenesis of embryonic epitheliumGO:00163311590.026
acylglycerol metabolic processGO:0006639550.026
purine containing compound metabolic processGO:00725213110.026
Fly
urogenital system developmentGO:00016552610.026
alcohol metabolic processGO:00060661160.026
metal ion homeostasisGO:00550651890.025
protein homooligomerizationGO:0051260430.025
digestive tract morphogenesisGO:00485461470.024
cellular response to oxygen radicalGO:0071450140.024
purine nucleotide metabolic processGO:00061633020.024
Fly
regulation of cellular amine metabolic processGO:0033238200.024
regulation of reactive oxygen species metabolic processGO:2000377400.023
divalent metal ion transportGO:00708381720.023
cell type specific apoptotic processGO:00972852680.023
tricarboxylic acid metabolic processGO:007235050.022
phagocytosisGO:0006909660.022
striated muscle tissue developmentGO:00147062930.022
regulation of organelle organizationGO:00330432890.022
germ cell developmentGO:00072811850.022
protein targetingGO:00066051430.022
histone modificationGO:00165701590.022
positive regulation of hydrolase activityGO:00513451480.022
amino acid betaine metabolic processGO:000657770.022
cation transportGO:00068123990.022
development of primary male sexual characteristicsGO:0046546880.022
glycerolipid metabolic processGO:00464861220.022
sulfur compound metabolic processGO:00067901000.021
purine nucleoside triphosphate catabolic processGO:00091462030.021
cellular response to dna damage stimulusGO:00069742070.021
cellular response to cytokine stimulusGO:00713451890.021
action potentialGO:0001508780.020
regulation of mitochondrial membrane potentialGO:0051881170.019
intracellular protein transportGO:00068862040.019
cellular response to steroid hormone stimulusGO:0071383330.019
epithelial cell proliferationGO:00506731740.019
regulation of ion transportGO:00432692150.019
acyl coa metabolic processGO:0006637190.019
regulation of cell activationGO:00508652890.019
microtubule based processGO:00070172360.019
sulfur compound biosynthetic processGO:0044272370.018
anion transportGO:00068201770.018
sensory perceptionGO:00076002450.018
fatty acid beta oxidationGO:0006635160.018
regulation of inflammatory responseGO:00507271470.018
chemotaxisGO:00069352470.018
regulation of blood pressureGO:0008217930.018
negative regulation of oxidative stress induced cell deathGO:190320290.018
maintenance of locationGO:0051235890.018
divalent inorganic cation transportGO:00725111780.018
purine nucleoside triphosphate metabolic processGO:00091442260.018
Fly
inorganic cation transmembrane transportGO:00986622070.018
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.018
nuclear transportGO:00511691390.018
purine nucleoside monophosphate metabolic processGO:0009126810.017
Fly
adult behaviorGO:00305341350.017
positive regulation of cellular amino acid metabolic processGO:004576430.017
organophosphate catabolic processGO:00464342320.017
regulation of kinase activityGO:00435492490.017
cellular response to superoxideGO:0071451140.017
cellular response to hormone stimulusGO:00328701500.017
glycerophospholipid metabolic processGO:0006650710.017
cellular response to organonitrogen compoundGO:00714171450.017
pyridine containing compound metabolic processGO:0072524140.017
reactive oxygen species biosynthetic processGO:190340980.017
determination of adult lifespanGO:0008340110.017
cytoplasmic transportGO:00164822340.016
tissue homeostasisGO:00018941150.016
positive regulation of protein modification processGO:00314012990.016
ribonucleoside monophosphate metabolic processGO:0009161800.016
Fly
calcium ion transportGO:00068161590.016
protein catabolic processGO:00301632210.016
dicarboxylic acid metabolic processGO:0043648180.016
ribonucleoside triphosphate metabolic processGO:00091992200.016
Fly
regulation of transmembrane transportGO:00347621280.016
wound healingGO:00420601570.015
cellular carbohydrate metabolic processGO:00442621190.015
fatty acid metabolic processGO:00066311210.015
male sex differentiationGO:00466611090.015
response to radiationGO:00093141650.015
hydrogen peroxide metabolic processGO:0042743160.015
hormone metabolic processGO:0042445860.015
innate immune responseGO:00450871570.015
regulation of leukocyte differentiationGO:19021051590.015
muscle tissue developmentGO:00605373080.015
response to molecule of bacterial originGO:00022371430.015
peptide metabolic processGO:0006518460.015
gonad developmentGO:00084061410.015
nicotinamide nucleotide metabolic processGO:0046496120.015
cellular response to acid chemicalGO:0071229680.015
age dependent response to oxidative stressGO:000130630.015
chromatin modificationGO:00165681870.015
organophosphate biosynthetic processGO:00904071220.015
regulation of blood vessel sizeGO:0050880560.015
regulation of lymphocyte activationGO:00512492400.015
telencephalon developmentGO:00215371860.015
negative regulation of cell proliferationGO:00082852960.015
cellular amide metabolic processGO:0043603580.015
ribonucleoside metabolic processGO:00091192450.015
Fly
divalent inorganic cation homeostasisGO:00725071380.014
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.014
lipid localizationGO:00108761260.014
angiogenesisGO:00015252010.014
cellular response to organic cyclic compoundGO:0071407870.014
posttranscriptional regulation of gene expressionGO:00106081550.014
developmental pigmentationGO:0048066400.014
cellular chemical homeostasisGO:00550822150.014
cellular transition metal ion homeostasisGO:0046916320.014
regulation of multi organism processGO:00439001110.014
digestive tract developmentGO:00485651900.014
neuron migrationGO:00017641220.014
regulation of cysteine type endopeptidase activityGO:2000116650.014
positive regulation of cellular amine metabolic processGO:003324050.014
phospholipid metabolic processGO:0006644870.014
digestive system developmentGO:00551232000.014
regulation of establishment of protein localizationGO:00702011810.014
extrinsic apoptotic signaling pathwayGO:00971911260.014
embryonic epithelial tube formationGO:00018381300.014
regulation of secretionGO:00510462740.014
superoxide metabolic processGO:0006801270.014
response to extracellular stimulusGO:00099911270.014
response to osmotic stressGO:0006970210.013
response to acid chemicalGO:00011011110.013
protein localization to membraneGO:00726571080.013
vascular process in circulatory systemGO:0003018620.013
cellular response to amino acid stimulusGO:0071230290.013
lymphocyte mediated immunityGO:00024491390.013
regulation of hormone levelsGO:00108172110.013
blood vessel morphogenesisGO:00485142850.013
regulation of cytokine productionGO:00018172660.013
nucleoside metabolic processGO:00091162460.013
Fly
muscle cell differentiationGO:00426922610.013
establishment of protein localization to organelleGO:00725941180.013
plasma membrane organizationGO:0007009900.013
negative regulation of cellular amine metabolic processGO:003323910.013
monocarboxylic acid biosynthetic processGO:0072330610.012
molting cycleGO:0042303900.012
cellular ion homeostasisGO:00068731650.012
protein secretionGO:00093061110.012
regulation of lipid metabolic processGO:00192161180.012
production of molecular mediator of immune responseGO:00024401030.012
positive regulation of antimicrobial peptide productionGO:000222510.012
heterocycle catabolic processGO:00467002800.012
amide transportGO:00428861380.012
gastrulationGO:00073691160.012
mitochondrion morphogenesisGO:0070584130.012
neural precursor cell proliferationGO:00613511210.012
nucleoside phosphate biosynthetic processGO:1901293790.012
retinoid metabolic processGO:0001523240.012
regulation of cellular response to stressGO:00801351590.012
muscle fiber developmentGO:0048747760.012
osteoclast differentiationGO:0030316620.012
response to peptideGO:19016521360.012
regulation of neuron apoptotic processGO:00435231220.012
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.012
regulation of defense responseGO:00313472330.012
negative regulation of endopeptidase activityGO:0010951440.012
multi multicellular organism processGO:00447061090.011
camera type eye developmentGO:00430102660.011
regulation of lymphocyte differentiationGO:00456191070.011
cytokine productionGO:00018163190.011
positive regulation of cell developmentGO:00107202370.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
regulation of inflammatory response to antigenic stimulusGO:0002861210.011
organic hydroxy compound transportGO:0015850930.011
regulation of epithelial cell proliferationGO:00506781410.011
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.011
negative regulation of phosphate metabolic processGO:00459361840.011
nadh metabolic processGO:000673410.011
cellular response to estrogen stimulusGO:0071391120.011
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.011
regulation of protein transportGO:00512231630.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
calcium ion homeostasisGO:00550741270.010
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.010
cardiac muscle tissue developmentGO:00487381300.010
oxygen homeostasisGO:003236420.010
regulation of ion transmembrane transportGO:00347651190.010
alpha amino acid biosynthetic processGO:1901607150.010
negative regulation of cellular protein metabolic processGO:00322692470.010
negative regulation of blood pressureGO:0045776220.010
carbohydrate derivative biosynthetic processGO:19011371830.010
regulation of antibacterial peptide productionGO:000278610.010
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.010
immune effector processGO:00022523210.010
carbohydrate homeostasisGO:00335001280.010
homeostasis of number of cells within a tissueGO:0048873250.010
neuron deathGO:00709971540.010
aldehyde catabolic processGO:004618540.010
cell activation involved in immune responseGO:00022631260.010
regulation of mitochondrial translationGO:007012930.010

Aifm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.388
inherited metabolic disorderDOID:65500.075
amino acid metabolic disorderDOID:925200.064
central nervous system diseaseDOID:33100.045
disease of anatomical entityDOID:700.045
nervous system diseaseDOID:86300.045
hematopoietic system diseaseDOID:7400.044
blood coagulation diseaseDOID:124700.044
immune system diseaseDOID:291400.044
hemorrhagic diseaseDOID:221300.044
neurodegenerative diseaseDOID:128900.022
disease of cellular proliferationDOID:1456600.022
carbohydrate metabolic disorderDOID:297800.018
musculoskeletal system diseaseDOID:1700.012
muscular diseaseDOID:008000000.012
blood platelet diseaseDOID:221800.011