| coenzyme metabolic process | GO:0006732 | 52 | 0.521 | |
| organic acid catabolic process | GO:0016054 | 51 | 0.512 | Rat |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.501 | Rat |
| branched chain amino acid catabolic process | GO:0009083 | 2 | 0.336 | Rat |
| cellular amino acid catabolic process | GO:0009063 | 25 | 0.328 | Rat |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.230 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.225 | |
| alpha amino acid metabolic process | GO:1901605 | 59 | 0.224 | Rat |
| carboxylic acid catabolic process | GO:0046395 | 51 | 0.200 | Rat |
| acetate metabolic process | GO:0006083 | 1 | 0.190 | |
| sulfur compound metabolic process | GO:0006790 | 100 | 0.186 | |
| cellular modified amino acid metabolic process | GO:0006575 | 63 | 0.182 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.170 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.159 | Rat |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.153 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.139 | |
| oxidation reduction process | GO:0055114 | 342 | 0.127 | Human Rat |
| alpha amino acid catabolic process | GO:1901606 | 18 | 0.125 | Rat |
| cofactor metabolic process | GO:0051186 | 80 | 0.123 | |
| ribonucleoside bisphosphate metabolic process | GO:0033875 | 9 | 0.117 | |
| small molecule catabolic process | GO:0044282 | 71 | 0.100 | Rat |
| amine metabolic process | GO:0009308 | 45 | 0.098 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.089 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.083 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.080 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.073 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.070 | |
| thioester metabolic process | GO:0035383 | 19 | 0.068 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.067 | |
| coenzyme a metabolic process | GO:0015936 | 8 | 0.067 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.065 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.065 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.061 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.060 | |
| pyrimidine containing compound catabolic process | GO:0072529 | 3 | 0.060 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.059 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.057 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.055 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.054 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.054 | |
| coenzyme biosynthetic process | GO:0009108 | 23 | 0.052 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.051 | |
| acyl coa metabolic process | GO:0006637 | 19 | 0.049 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.049 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.047 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.045 | |
| fatty acid oxidation | GO:0019395 | 28 | 0.045 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.043 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.040 | |
| hormone metabolic process | GO:0042445 | 86 | 0.038 | |
| generation of precursor metabolites and energy | GO:0006091 | 103 | 0.038 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.038 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.037 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.037 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.034 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.034 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.034 | |
| lipid biosynthetic process | GO:0008610 | 179 | 0.033 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.032 | |
| nucleoside bisphosphate metabolic process | GO:0033865 | 9 | 0.032 | |
| camera type eye development | GO:0043010 | 266 | 0.031 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.031 | |
| cellular carbohydrate metabolic process | GO:0044262 | 119 | 0.029 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.028 | |
| cellular amino acid biosynthetic process | GO:0008652 | 22 | 0.028 | |
| polyamine catabolic process | GO:0006598 | 2 | 0.028 | |
| transmembrane transport | GO:0055085 | 412 | 0.028 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.027 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.026 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.026 | |
| transmission of nerve impulse | GO:0019226 | 76 | 0.025 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.025 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.025 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.024 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.024 | |
| heart morphogenesis | GO:0003007 | 178 | 0.024 | |
| muscle tissue development | GO:0060537 | 308 | 0.024 | |
| fatty acid metabolic process | GO:0006631 | 121 | 0.024 | |
| organic acid biosynthetic process | GO:0016053 | 86 | 0.024 | |
| cellular lipid catabolic process | GO:0044242 | 52 | 0.024 | |
| appendage development | GO:0048736 | 166 | 0.023 | |
| cation transport | GO:0006812 | 399 | 0.023 | |
| hepaticobiliary system development | GO:0061008 | 67 | 0.023 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.023 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.023 | |
| glycerolipid metabolic process | GO:0046486 | 122 | 0.023 | |
| action potential | GO:0001508 | 78 | 0.022 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.022 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.022 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.022 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.022 | |
| organelle fission | GO:0048285 | 170 | 0.022 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.022 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.021 | |
| lung development | GO:0030324 | 164 | 0.021 | |
| coenzyme catabolic process | GO:0009109 | 5 | 0.021 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.021 | |
| carboxylic acid biosynthetic process | GO:0046394 | 86 | 0.021 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.021 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.020 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.020 | |
| response to nutrient levels | GO:0031667 | 109 | 0.020 | |
| response to increased oxygen levels | GO:0036296 | 2 | 0.020 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.020 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.020 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.019 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.019 | |
| steroid metabolic process | GO:0008202 | 119 | 0.019 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.019 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.019 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.019 | |
| urogenital system development | GO:0001655 | 261 | 0.019 | |
| glycerol ether metabolic process | GO:0006662 | 2 | 0.018 | |
| multicellular organism growth | GO:0035264 | 161 | 0.018 | |
| ensheathment of neurons | GO:0007272 | 76 | 0.018 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.018 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.018 | |
| maintenance of location | GO:0051235 | 89 | 0.018 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.018 | |
| protein catabolic process | GO:0030163 | 221 | 0.018 | |
| sulfur amino acid metabolic process | GO:0000096 | 9 | 0.018 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.018 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.018 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.018 | |
| mapk cascade | GO:0000165 | 281 | 0.017 | |
| gland development | GO:0048732 | 330 | 0.017 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.017 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.017 | |
| neuronal action potential | GO:0019228 | 54 | 0.017 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.017 | |
| establishment of protein localization to peroxisome | GO:0072663 | 4 | 0.017 | |
| glycoprotein biosynthetic process | GO:0009101 | 89 | 0.016 | |
| myelination | GO:0042552 | 74 | 0.016 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.016 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.016 | |
| response to acid chemical | GO:0001101 | 111 | 0.016 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.016 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.016 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.016 | |
| neutral lipid metabolic process | GO:0006638 | 57 | 0.016 | |
| response to peptide hormone | GO:0043434 | 127 | 0.016 | |
| developmental maturation | GO:0021700 | 193 | 0.016 | |
| liver development | GO:0001889 | 66 | 0.016 | |
| ribose phosphate biosynthetic process | GO:0046390 | 59 | 0.015 | |
| telencephalon development | GO:0021537 | 186 | 0.015 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.015 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.015 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.015 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.015 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.015 | |
| pyrimidine containing compound metabolic process | GO:0072527 | 11 | 0.015 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.015 | |
| sulfur compound biosynthetic process | GO:0044272 | 37 | 0.015 | |
| digestive tract development | GO:0048565 | 190 | 0.015 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.015 | |
| glutamine family amino acid biosynthetic process | GO:0009084 | 2 | 0.015 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.015 | |
| fat cell differentiation | GO:0045444 | 160 | 0.015 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.015 | |
| nuclear division | GO:0000280 | 158 | 0.015 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.015 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.015 | |
| anatomical structure homeostasis | GO:0060249 | 145 | 0.015 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.015 | |
| small molecule biosynthetic process | GO:0044283 | 132 | 0.015 | |
| tissue homeostasis | GO:0001894 | 115 | 0.015 | |
| renal system development | GO:0072001 | 225 | 0.015 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.014 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 80 | 0.014 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.014 | |
| nadph regeneration | GO:0006740 | 2 | 0.014 | |
| positive regulation of secretion by cell | GO:1903532 | 114 | 0.014 | |
| macromolecule deacylation | GO:0098732 | 37 | 0.014 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.014 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.014 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.014 | |
| monocarboxylic acid catabolic process | GO:0072329 | 27 | 0.014 | |
| pyridine containing compound metabolic process | GO:0072524 | 14 | 0.014 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.014 | |
| regulation of defense response to bacterium | GO:1900424 | 3 | 0.014 | |
| chromatin modification | GO:0016568 | 187 | 0.014 | |
| dephosphorylation | GO:0016311 | 129 | 0.013 | |
| hexose metabolic process | GO:0019318 | 98 | 0.013 | |
| connective tissue development | GO:0061448 | 179 | 0.013 | |
| digestive system development | GO:0055123 | 200 | 0.013 | |
| endocytosis | GO:0006897 | 168 | 0.013 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.013 | |
| histone modification | GO:0016570 | 159 | 0.013 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.013 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.013 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.013 | |
| epithelial cell development | GO:0002064 | 159 | 0.013 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.013 | |
| atp catabolic process | GO:0006200 | 55 | 0.013 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.013 | |
| protein glycosylation | GO:0006486 | 55 | 0.013 | |
| sensory perception | GO:0007600 | 245 | 0.013 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.013 | |
| innate immune response | GO:0045087 | 157 | 0.013 | |
| cofactor biosynthetic process | GO:0051188 | 41 | 0.013 | |
| cell maturation | GO:0048469 | 127 | 0.013 | |
| immune effector process | GO:0002252 | 321 | 0.013 | |
| response to glucagon | GO:0033762 | 3 | 0.013 | |
| stem cell development | GO:0048864 | 219 | 0.013 | |
| response to hyperoxia | GO:0055093 | 2 | 0.013 | |
| regulation of secretion | GO:0051046 | 274 | 0.013 | |
| energy derivation by oxidation of organic compounds | GO:0015980 | 77 | 0.013 | |
| t cell activation | GO:0042110 | 289 | 0.012 | |
| regulation of cell activation | GO:0050865 | 289 | 0.012 | |
| myeloid cell homeostasis | GO:0002262 | 114 | 0.012 | |
| response to oxygen levels | GO:0070482 | 62 | 0.012 | |
| regulation of response to drug | GO:2001023 | 2 | 0.012 | |
| stem cell differentiation | GO:0048863 | 268 | 0.012 | |
| erythrocyte differentiation | GO:0030218 | 88 | 0.012 | |
| locomotory behavior | GO:0007626 | 195 | 0.012 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.012 | |
| circulatory system process | GO:0003013 | 197 | 0.012 | |
| lipid modification | GO:0030258 | 65 | 0.012 | |
| dicarboxylic acid metabolic process | GO:0043648 | 18 | 0.012 | |
| cellular response to lipid | GO:0071396 | 145 | 0.012 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.012 | |
| metencephalon development | GO:0022037 | 89 | 0.012 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.012 | |
| respiratory system development | GO:0060541 | 190 | 0.012 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.012 | |
| protein import into peroxisome matrix | GO:0016558 | 3 | 0.012 | |
| very long chain fatty acid catabolic process | GO:0042760 | 2 | 0.012 | |
| substantia nigra development | GO:0021762 | 2 | 0.012 | |
| limb development | GO:0060173 | 166 | 0.012 | |
| skin development | GO:0043588 | 220 | 0.012 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.012 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.012 | |
| cardiac muscle tissue development | GO:0048738 | 130 | 0.012 | |
| amp metabolic process | GO:0046033 | 4 | 0.011 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.011 | |
| cellular glucan metabolic process | GO:0006073 | 32 | 0.011 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.011 | |
| defense response to other organism | GO:0098542 | 197 | 0.011 | |
| germ cell development | GO:0007281 | 185 | 0.011 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.011 | |
| ear morphogenesis | GO:0042471 | 118 | 0.011 | |
| lateral inhibition | GO:0046331 | 1 | 0.011 | |
| muscle system process | GO:0003012 | 141 | 0.011 | |
| kidney development | GO:0001822 | 213 | 0.011 | |
| cellular homeostasis | GO:0019725 | 240 | 0.011 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.011 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.011 | |
| synaptic transmission | GO:0007268 | 329 | 0.011 | |
| protein localization to organelle | GO:0033365 | 185 | 0.011 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.011 | |
| cellular response to acid chemical | GO:0071229 | 68 | 0.011 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.011 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.011 | |
| response to monosaccharide | GO:0034284 | 67 | 0.011 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 79 | 0.011 | |
| neuron death | GO:0070997 | 154 | 0.011 | |
| chromatin organization | GO:0006325 | 206 | 0.011 | |
| acetyl coa biosynthetic process | GO:0006085 | 5 | 0.011 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.011 | |
| response to drug | GO:0042493 | 75 | 0.011 | |
| regulation of protein localization | GO:0032880 | 231 | 0.011 | |
| glucose homeostasis | GO:0042593 | 128 | 0.011 | |
| pyridine containing compound catabolic process | GO:0072526 | 4 | 0.011 | |
| protein import | GO:0017038 | 101 | 0.011 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.011 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.011 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.011 | |
| nad metabolic process | GO:0019674 | 7 | 0.011 | |
| male gamete generation | GO:0048232 | 285 | 0.011 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.011 | |
| response to catecholamine | GO:0071869 | 4 | 0.011 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.010 | |
| acylglycerol biosynthetic process | GO:0046463 | 18 | 0.010 | |
| positive regulation of lymphocyte activation | GO:0051251 | 140 | 0.010 | |
| response to inorganic substance | GO:0010035 | 96 | 0.010 | |
| purine containing compound biosynthetic process | GO:0072522 | 70 | 0.010 | |
| cytokine production | GO:0001816 | 319 | 0.010 | |
| peptide hormone secretion | GO:0030072 | 109 | 0.010 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.010 | |
| lipid homeostasis | GO:0055088 | 63 | 0.010 | |
| protein tetramerization | GO:0051262 | 23 | 0.010 | |
| chemotaxis | GO:0006935 | 247 | 0.010 | |
| limb morphogenesis | GO:0035108 | 149 | 0.010 | |
| erk1 and erk2 cascade | GO:0070371 | 77 | 0.010 | |
| dna metabolic process | GO:0006259 | 303 | 0.010 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.010 | |
| rhythmic process | GO:0048511 | 174 | 0.010 | |
| response to insulin | GO:0032868 | 100 | 0.010 | |
| cell junction assembly | GO:0034329 | 52 | 0.010 | |
| aldehyde catabolic process | GO:0046185 | 4 | 0.010 | |
| blood circulation | GO:0008015 | 195 | 0.010 | |
