Mus musculus

0 known processes

Tab3

TGF-beta activated kinase 1/MAP3K7 binding protein 3

(Aliases: 4921526G09Rik,mKIAA4135,Map3k7ip3,KIAA4135)

Tab3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein catabolic processGO:00301632210.664
proteolysis involved in cellular protein catabolic processGO:00516031470.569
modification dependent protein catabolic processGO:00199411330.553
cellular protein catabolic processGO:00442571550.482
ubiquitin dependent protein catabolic processGO:00065111290.474
modification dependent macromolecule catabolic processGO:00436321330.447
macromolecule catabolic processGO:00090572810.424
protein ubiquitinationGO:00165671710.343
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.315
protein modification by small protein conjugation or removalGO:00706472070.244
positive regulation of cellular catabolic processGO:00313311480.224
protein modification by small protein conjugationGO:00324461870.170
cellular macromolecule catabolic processGO:00442652060.145
regulation of cellular catabolic processGO:00313292420.116
myeloid cell differentiationGO:00300992330.103
protein polyubiquitinationGO:0000209330.103
purine ribonucleoside catabolic processGO:00461302050.101
small gtpase mediated signal transductionGO:0007264970.098
purine ribonucleoside triphosphate catabolic processGO:00092071990.095
meiosis iGO:0007127600.091
purine nucleoside metabolic processGO:00422782410.079
spermatogenesisGO:00072832840.076
posttranscriptional regulation of gene expressionGO:00106081550.074
wnt signaling pathwayGO:00160551880.073
organelle localizationGO:00516401790.073
regulation of cellular amine metabolic processGO:0033238200.065
purine nucleoside triphosphate catabolic processGO:00091462030.065
covalent chromatin modificationGO:00165691630.063
histone modificationGO:00165701590.063
proteasomal protein catabolic processGO:0010498980.063
nucleobase containing small molecule metabolic processGO:00550863520.062
chromatin organizationGO:00063252060.058
male gamete generationGO:00482322850.054
glycosyl compound metabolic processGO:19016572460.053
nucleoside metabolic processGO:00091162460.052
negative regulation of cellular component organizationGO:00511291940.049
i kappab kinase nf kappab signalingGO:0007249850.047
cellular homeostasisGO:00197252400.045
purine ribonucleotide metabolic processGO:00091502900.044
purine ribonucleoside metabolic processGO:00461282410.044
negative regulation of cellular protein metabolic processGO:00322692470.043
rho protein signal transductionGO:0007266320.043
positive regulation of macroautophagyGO:001623930.042
t cell activationGO:00421102890.042
response to growth factorGO:00708481980.041
establishment of organelle localizationGO:00516561220.041
ribose phosphate metabolic processGO:00196932910.041
heterocycle catabolic processGO:00467002800.039
ribonucleoside triphosphate catabolic processGO:00092031990.038
regulation of chromatin silencingGO:003193520.038
apoptotic signaling pathwayGO:00971903060.038
carbohydrate derivative catabolic processGO:19011362310.037
purine ribonucleoside triphosphate metabolic processGO:00092052200.036
ribonucleoside triphosphate metabolic processGO:00091992200.036
histone h3 k9 dimethylationGO:003612340.036
organonitrogen compound catabolic processGO:19015652640.035
purine containing compound catabolic processGO:00725232130.035
ribonucleotide catabolic processGO:00092612080.035
cellular response to nutrient levelsGO:0031669640.035
nucleoside phosphate catabolic processGO:19012922220.035
embryonic epithelial tube formationGO:00018381300.033
positive regulation of organelle organizationGO:00106381280.033
regulation of hydrolase activityGO:00513362460.033
cellular response to external stimulusGO:0071496880.033
purine nucleotide metabolic processGO:00061633020.032
respiratory system developmentGO:00605411900.032
organophosphate catabolic processGO:00464342320.032
glycosyl compound catabolic processGO:19016582060.032
regulation of cellular component biogenesisGO:00440871810.031
positive regulation of protein kinase activityGO:00458601440.031
compound eye developmentGO:004874910.031
metal ion homeostasisGO:00550651890.031
nucleoside triphosphate catabolic processGO:00091432050.031
regulation of cellular protein catabolic processGO:1903362610.031
organelle fissionGO:00482851700.031
gtp catabolic processGO:00061841430.031
positive regulation of cellular amino acid metabolic processGO:004576430.030
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.030
guanosine containing compound metabolic processGO:19010681440.030
male meiosis iGO:0007141160.029
regulation of organelle organizationGO:00330432890.029
cellular response to growth factor stimulusGO:00713631970.029
microtubule based processGO:00070172360.028
positive regulation of apoptotic signaling pathwayGO:2001235950.028
regulation of cellular amino acid metabolic processGO:000652150.028
organic cyclic compound catabolic processGO:19013612950.028
positive regulation of proteolysisGO:0045862850.028
nucleotide catabolic processGO:00091662170.027
positive regulation of cellular amine metabolic processGO:003324050.027
spermatid developmentGO:00072861080.027
amine metabolic processGO:0009308450.027
exocytosisGO:00068871210.027
germ cell developmentGO:00072811850.027
erythrocyte differentiationGO:0030218880.027
ras protein signal transductionGO:0007265770.027
regulation of synaptic growth at neuromuscular junctionGO:000858240.027
positive regulation of kinase activityGO:00336741550.026
spermatid nucleus elongationGO:000729040.026
regulation of kinase activityGO:00435492490.026
negative regulation of protein metabolic processGO:00512482820.026
dna metabolic processGO:00062593030.026
purine ribonucleotide catabolic processGO:00091542080.026
cation homeostasisGO:00550802120.026
microtubule cytoskeleton organizationGO:00002261570.026
cellular amine metabolic processGO:0044106440.026
vesicle localizationGO:0051648860.026
regulation of histone modificationGO:0031056560.026
guanosine containing compound catabolic processGO:19010691440.026
aromatic compound catabolic processGO:00194392860.026
regulation of transferase activityGO:00513382630.026
gtp metabolic processGO:00460391440.026
negative regulation of intracellular signal transductionGO:19025321670.025
cytoplasmic transportGO:00164822340.025
regulation of apoptotic signaling pathwayGO:20012331970.025
methylationGO:00322591340.025
defense response to other organismGO:00985421970.025
ribonucleoside catabolic processGO:00424542060.025
negative regulation of molecular functionGO:00440922580.025
regulation of wnt signaling pathwayGO:00301111230.024
regulation of protein catabolic processGO:00421761080.024
development of primary sexual characteristicsGO:00451371430.024
cell adhesionGO:00071553290.024
purine nucleoside catabolic processGO:00061522050.024
myeloid cell homeostasisGO:00022621140.024
cellular chemical homeostasisGO:00550822150.024
regulation of ras gtpase activityGO:0032318880.023
regulation of nucleotide metabolic processGO:00061401690.023
actin cytoskeleton organizationGO:00300362200.023
cellular nitrogen compound catabolic processGO:00442702800.023
cellular response to dna damage stimulusGO:00069742070.023
intermediate filament based processGO:0045103270.023
purine nucleotide catabolic processGO:00061952110.022
immune effector processGO:00022523210.022
regulation of defense responseGO:00313472330.022
axonogenesisGO:00074092740.022
osteoclast differentiationGO:0030316620.022
purine containing compound metabolic processGO:00725213110.022
cation transportGO:00068123990.022
establishment of protein localization to organelleGO:00725941180.022
histone h2a ubiquitinationGO:003352230.021
nucleotide metabolic processGO:00091173320.021
protein polymerizationGO:0051258570.021
synaptic transmissionGO:00072683290.021
regulation of cellular response to growth factor stimulusGO:0090287820.021
gonad developmentGO:00084061410.021
regulation of chromosome organizationGO:0033044830.021
regulation of response to woundingGO:19030341890.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.021
ribonucleoside metabolic processGO:00091192450.020
transforming growth factor beta receptor signaling pathwayGO:0007179710.020
negative regulation of hydrolase activityGO:0051346710.020
positive regulation of hydrolase activityGO:00513451480.020
mitotic cell cycle processGO:19030471590.020
localization within membraneGO:005166840.020
regulation of peptidase activityGO:0052547960.020
positive regulation of apoptotic processGO:00430652170.020
regulation of cell projection organizationGO:00313442060.020
nuclear divisionGO:00002801580.020
meiotic cell cycleGO:00513211220.020
regionalizationGO:00030023370.019
peptidyl amino acid modificationGO:00181933360.019
phagocytosisGO:0006909660.019
chromatin modificationGO:00165681870.019
mitotic cell cycleGO:00002781950.019
protein maturationGO:00516041760.019
cellular response to transforming growth factor beta stimulusGO:0071560880.019
negative regulation of immune system processGO:00026832090.019
protein autophosphorylationGO:0046777610.019
negative regulation of cell proliferationGO:00082852960.019
macromolecular complex disassemblyGO:0032984430.019
endomembrane system organizationGO:00102561470.018
gland developmentGO:00487323300.018
membrane organizationGO:00610242450.018
macroautophagyGO:0016236210.018
response to extracellular stimulusGO:00099911270.018
establishment or maintenance of cell polarityGO:0007163860.018
digestive system developmentGO:00551232000.018
ion transmembrane transportGO:00342203610.018
regulation of cellular component sizeGO:00325351210.018
respiratory tube developmentGO:00303231670.018
extrinsic apoptotic signaling pathwayGO:00971911260.018
regulation of cell migrationGO:00303342190.018
muscle cell fate specificationGO:004269410.018
regulation of proteolysisGO:00301621640.017
negative regulation of protein phosphorylationGO:00019331260.017
copii coated vesicle buddingGO:009011420.017
purine nucleoside triphosphate metabolic processGO:00091442260.017
single organism cell adhesionGO:00986021560.017
lipid localizationGO:00108761260.017
regulation of cellular response to stressGO:00801351590.017
canonical wnt signaling pathwayGO:00600701300.017
rna 3 end processingGO:0031123200.017
macromolecule methylationGO:00434141200.017
fat cell differentiationGO:00454441600.017
negative regulation of protein modification processGO:00314001630.017
cell matrix adhesionGO:0007160680.017
positive regulation of programmed cell deathGO:00430682180.017
interleukin 6 productionGO:0032635580.017
cellular amino acid metabolic processGO:00065201030.017
regulation of protein kinase activityGO:00458592320.017
negative regulation of apoptotic signaling pathwayGO:20012341040.017
positive regulation of protein modification processGO:00314012990.017
developmental growth involved in morphogenesisGO:00605601380.016
regulation of autophagyGO:0010506300.016
establishment or maintenance of cytoskeleton polarityGO:003095220.016
regulation of response to dna damage stimulusGO:2001020340.016
placenta developmentGO:00018901400.016
response to nutrient levelsGO:00316671090.016
regulation of chromatin modificationGO:1903308570.016
protein deubiquitinationGO:0016579190.016
cellular response to lipidGO:00713961450.016
regulation of innate immune responseGO:0045088910.016
nucleoside phosphate metabolic processGO:00067533380.016
transition metal ion homeostasisGO:0055076540.016
response to organic cyclic compoundGO:00140701980.016
asymmetric stem cell divisionGO:009872230.016
vesicle coatingGO:000690120.016
regulation of body fluid levelsGO:00508781620.016
cellular response to extracellular stimulusGO:0031668810.016
cell type specific apoptotic processGO:00972852680.015
activation of innate immune responseGO:0002218560.015
bmp signaling pathwayGO:0030509930.015
positive regulation of transferase activityGO:00513471670.015
positive regulation of homeostatic processGO:0032846640.015
small molecule biosynthetic processGO:00442831320.015
gpi anchor biosynthetic processGO:000650660.015
transmembrane transportGO:00550854120.015
regulation of anatomical structure sizeGO:00900661780.015
positive regulation of purine nucleotide metabolic processGO:19005441140.015
regulation of ion transmembrane transportGO:00347651190.015
regulation of protein complex assemblyGO:0043254830.015
protein modification by small protein removalGO:0070646210.015
response to lipopolysaccharideGO:00324961280.015
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.015
regulation of lymphocyte proliferationGO:00506701170.015
cellular response to biotic stimulusGO:0071216920.015
protein localization to organelleGO:00333651850.015
regulation of translationGO:0006417710.015
cellular ion homeostasisGO:00068731650.015
intrinsic apoptotic signaling pathwayGO:00971931320.015
positive regulation of protein serine threonine kinase activityGO:00719021060.015
regulation of transmembrane transportGO:00347621280.014
snrna metabolic processGO:001607310.014
protein localization to vacuoleGO:007266540.014
protein targetingGO:00066051430.014
negative regulation of ripoptosome assembly involved in necroptotic processGO:190244330.014
positive regulation of mitotic sister chromatid separationGO:190197020.014
meiotic cell cycle processGO:1903046770.014
positive regulation of ras gtpase activityGO:0032320650.014
asymmetric neuroblast divisionGO:005505910.014
cellular protein complex assemblyGO:00436231160.014
synapse organizationGO:00508081250.014
inorganic ion transmembrane transportGO:00986602340.014
activation of nf kappab inducing kinase activityGO:000725040.014
oocyte axis specificationGO:000730920.014
homeostasis of number of cellsGO:00488722100.014
nucleoside monophosphate catabolic processGO:0009125590.014
regulation of proteasomal protein catabolic processGO:0061136460.013
organic hydroxy compound metabolic processGO:19016152030.013
regulation of interleukin 6 productionGO:0032675550.013
regulation of feeding behaviorGO:006025930.013
reactive oxygen species metabolic processGO:0072593840.013
negative regulation of phosphate metabolic processGO:00459361840.013
cellular response to cytokine stimulusGO:00713451890.013
regulation of vesicle mediated transportGO:00606271390.013
regulation of rho protein signal transductionGO:0035023710.013
appendage developmentGO:00487361660.013
regulation of t cell activationGO:00508631700.013
gpi anchor metabolic processGO:000650570.013
actin filament organizationGO:00070151130.013
divalent inorganic cation homeostasisGO:00725071380.013
nucleoside catabolic processGO:00091642060.013
regulation of actin filament polymerizationGO:0030833380.013
cellular ketone metabolic processGO:0042180840.013
morphogenesis of embryonic epitheliumGO:00163311590.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.013
protein localization to chromosome centromeric regionGO:007145910.013
rab protein signal transductionGO:003248210.013
stress activated mapk cascadeGO:0051403800.013
cellular response to hormone stimulusGO:00328701500.013
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.013
regulation of purine nucleotide metabolic processGO:19005421690.013
negative regulation of growthGO:0045926990.013
regulation of defense response to bacteriumGO:190042430.012
positive regulation of protein phosphorylationGO:00019342420.012
mitochondrial transportGO:0006839360.012
multicellular organism growthGO:00352641610.012
regulation of endopeptidase activityGO:0052548890.012
divalent inorganic cation transportGO:00725111780.012
regulation of androgen receptor signaling pathwayGO:006076530.012
cellular response to starvationGO:0009267570.012
demethylationGO:0070988230.012
histone lysine demethylationGO:0070076130.012
anion transportGO:00068201770.012
actin filament based movementGO:0030048230.012
rna processingGO:00063961050.012
fertilizationGO:00095661270.012
endocytosisGO:00068971680.012
response to transforming growth factor betaGO:0071559880.012
regulation of nucleoside metabolic processGO:00091181300.012
regulation of lymphocyte activationGO:00512492400.012
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.012
maintenance of locationGO:0051235890.011
glucose homeostasisGO:00425931280.011
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787250.011
blastocyst developmentGO:0001824800.011
protein acylationGO:0043543640.011
nitrogen compound transportGO:00717052710.011
carbon catabolite regulation of transcriptionGO:004599040.011
golgi to endosome transportGO:000689530.011
sensory perceptionGO:00076002450.011
protein targeting to vacuoleGO:000662330.011
vesicle organizationGO:0016050600.011
leukocyte activation involved in immune responseGO:00023661260.011
regulation of cellular ketone metabolic processGO:0010565660.011
negative regulation of kinase activityGO:0033673810.011
sequestering of calcium ionGO:0051208180.011
intermediate filament cytoskeleton organizationGO:0045104260.011
nucleoside triphosphate metabolic processGO:00091412300.011
negative regulation of lymphocyte activationGO:0051250910.011
ribonucleotide metabolic processGO:00092592910.011
dna repairGO:00062811070.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.011
lung developmentGO:00303241640.011
convergent extensionGO:0060026140.011
cellular transition metal ion homeostasisGO:0046916320.011
regulation of secretionGO:00510462740.011
iron ion homeostasisGO:0055072360.011
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.011
positive regulation of nucleotide metabolic processGO:00459811140.011
calcium ion homeostasisGO:00550741270.011
inorganic cation transmembrane transportGO:00986622070.011
cell divisionGO:00513011200.011
microtubule based movementGO:0007018840.011
cellularizationGO:000734910.011
cellular metal ion homeostasisGO:00068751510.011
positive regulation of insulin receptor signaling pathwayGO:004662840.011
negative regulation of cell growthGO:0030308440.011
multi multicellular organism processGO:00447061090.011
regulation of histone h3 k9 methylationGO:005157080.011
negative regulation of neuron deathGO:1901215980.011
lymphocyte differentiationGO:00300982420.010
positive regulation of protein catabolic processGO:0045732600.010
negative regulation of synapse assemblyGO:005196430.010
cellular response to organic cyclic compoundGO:0071407870.010
negative regulation of phosphorus metabolic processGO:00105631840.010
synapsisGO:0007129340.010
negative regulation of chromatin silencingGO:003193610.010
divalent metal ion transportGO:00708381720.010
regulation of bmp signaling pathwayGO:0030510600.010
positive regulation of intracellular transportGO:0032388700.010
positive regulation of wnt signaling pathwayGO:0030177450.010
regulation of axon extensionGO:0030516430.010

Tab3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.071
disease of cellular proliferationDOID:1456600.071
organ system cancerDOID:005068600.071
nervous system diseaseDOID:86300.023
disease of anatomical entityDOID:700.023
thoracic cancerDOID:509300.014
musculoskeletal system diseaseDOID:1700.013