Mus musculus

0 known processes

Spns1

spinster homolog 1 (Drosophila)

(Aliases: 2210013K02Rik,Spin1,Spinl)

Spns1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular ketone metabolic processGO:0010565660.122
lipid biosynthetic processGO:00086101790.098
purine ribonucleoside catabolic processGO:00461302050.093
vacuole organizationGO:0007033380.089
Fly
skin developmentGO:00435882200.086
macroautophagyGO:0016236210.083
positive regulation of programmed cell deathGO:00430682180.082
protein localization to organelleGO:00333651850.077
cytoplasmic transportGO:00164822340.073
Fly
positive regulation of protein modification processGO:00314012990.073
regulation of protein localizationGO:00328802310.068
mapk cascadeGO:00001652810.067
regulation of hydrolase activityGO:00513362460.066
nucleoside triphosphate metabolic processGO:00091412300.064
cellular ketone metabolic processGO:0042180840.063
regulation of organelle organizationGO:00330432890.062
cellular lipid metabolic processGO:00442553230.060
Mouse
ion transmembrane transportGO:00342203610.060
retrograde transport endosome to golgiGO:004214720.059
germ cell developmentGO:00072811850.057
Worm Fly
cellular amino acid metabolic processGO:00065201030.057
regulation of mapk cascadeGO:00434082480.057
organic cyclic compound catabolic processGO:19013612950.057
response to organonitrogen compoundGO:00102432460.056
epidermis developmentGO:00085441870.056
protein targetingGO:00066051430.055
regulation of cellular amine metabolic processGO:0033238200.055
nitrogen compound transportGO:00717052710.052
proteolysis involved in cellular protein catabolic processGO:00516031470.052
organonitrogen compound catabolic processGO:19015652640.051
locomotory behaviorGO:00076261950.051
regulation of neuron differentiationGO:00456642810.050
purine nucleoside metabolic processGO:00422782410.050
positive regulation of hydrolase activityGO:00513451480.050
intracellular protein transportGO:00068862040.049
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.049
Fly
protein localization to membraneGO:00726571080.049
spermatogenesisGO:00072832840.048
regulation of cellular amino acid metabolic processGO:000652150.048
negative regulation of molecular functionGO:00440922580.047
cellular response to nutrient levelsGO:0031669640.047
Fly
anion transportGO:00068201770.047
urogenital system developmentGO:00016552610.047
multicellular organism growthGO:00352641610.046
aromatic compound catabolic processGO:00194392860.045
nucleoside triphosphate catabolic processGO:00091432050.045
sensory perceptionGO:00076002450.045
glycerolipid metabolic processGO:00464861220.044
establishment of protein localization to organelleGO:00725941180.044
synaptic transmissionGO:00072683290.043
Fly
positive regulation of cell deathGO:00109422240.042
purine ribonucleoside triphosphate catabolic processGO:00092071990.041
glycosyl compound catabolic processGO:19016582060.040
lipid localizationGO:00108761260.040
Mouse
transmembrane transportGO:00550854120.040
membrane organizationGO:00610242450.040
positive regulation of protein phosphorylationGO:00019342420.040
modification dependent macromolecule catabolic processGO:00436321330.039
amine metabolic processGO:0009308450.039
negative regulation of protein metabolic processGO:00512482820.039
positive regulation of cell developmentGO:00107202370.039
purine ribonucleoside triphosphate metabolic processGO:00092052200.039
cognitionGO:00508901490.038
protein maturationGO:00516041760.038
response to light stimulusGO:00094161350.037
regulation of synaptic growth at neuromuscular junctionGO:000858240.037
Fly
ribonucleotide metabolic processGO:00092592910.037
histone modificationGO:00165701590.037
male gamete generationGO:00482322850.037
negative regulation of cellular component organizationGO:00511291940.037
kidney developmentGO:00018222130.037
steroid metabolic processGO:00082021190.036
ribonucleoside triphosphate catabolic processGO:00092031990.036
ribonucleoside triphosphate metabolic processGO:00091992200.036
photoreceptor cell differentiationGO:0046530520.035
negative regulation of phosphorylationGO:00423261660.035
purine containing compound catabolic processGO:00725232130.034
cellular amine metabolic processGO:0044106440.034
positive regulation of apoptotic processGO:00430652170.034
purine ribonucleoside metabolic processGO:00461282410.034
ribonucleoside catabolic processGO:00424542060.033
purine containing compound metabolic processGO:00725213110.033
response to starvationGO:0042594650.033
Fly
negative regulation of cellular protein metabolic processGO:00322692470.033
glycosyl compound metabolic processGO:19016572460.033
regulation of cell adhesionGO:00301551540.033
nucleotide catabolic processGO:00091662170.033
regulation of cellular catabolic processGO:00313292420.033
regulation of cell motilityGO:20001452360.032
ribonucleoside metabolic processGO:00091192450.032
regulation of hormone levelsGO:00108172110.031
ubiquitin dependent protein catabolic processGO:00065111290.031
nucleoside phosphate catabolic processGO:19012922220.031
oxidation reduction processGO:00551143420.031
monocarboxylic acid metabolic processGO:00327871910.031
cellular response to growth factor stimulusGO:00713631970.031
protein importGO:00170381010.031
nucleotide metabolic processGO:00091173320.031
negative regulation of synapse assemblyGO:005196430.031
positive regulation of transferase activityGO:00513471670.030
retina development in camera type eyeGO:00600411190.030
regulation of nucleoside metabolic processGO:00091181300.030
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.029
bmp signaling pathwayGO:0030509930.029
organic hydroxy compound metabolic processGO:19016152030.029
spermatid differentiationGO:00485151150.029
response to radiationGO:00093141650.029
nuclear transportGO:00511691390.029
nucleoside metabolic processGO:00091162460.028
posttranscriptional regulation of gene expressionGO:00106081550.028
regulation of protein maturationGO:1903317960.028
cellular nitrogen compound catabolic processGO:00442702800.028
regulation of anatomical structure sizeGO:00900661780.028
rhythmic processGO:00485111740.028
macromolecule glycosylationGO:0043413550.028
gland developmentGO:00487323300.027
peptidyl amino acid modificationGO:00181933360.027
peptide transportGO:00158331330.027
ribonucleotide catabolic processGO:00092612080.027
cellular homeostasisGO:00197252400.027
tissue homeostasisGO:00018941150.027
purine nucleotide catabolic processGO:00061952110.027
maintenance of locationGO:0051235890.026
blood vessel morphogenesisGO:00485142850.026
purine nucleoside triphosphate metabolic processGO:00091442260.026
protein processingGO:00164851630.026
negative regulation of phosphate metabolic processGO:00459361840.025
anatomical structure homeostasisGO:00602491450.025
negative regulation of neuron differentiationGO:00456651010.025
purine nucleoside catabolic processGO:00061522050.025
apoptotic signaling pathwayGO:00971903060.025
protein catabolic processGO:00301632210.025
ossificationGO:00015032160.025
regulation of lipid metabolic processGO:00192161180.025
positive regulation of cellular catabolic processGO:00313311480.025
cell type specific apoptotic processGO:00972852680.025
Fly
positive regulation of cellular amino acid metabolic processGO:004576430.025
fertilizationGO:00095661270.024
positive regulation of kinase activityGO:00336741550.024
autophagyGO:0006914450.024
nuclear importGO:0051170950.024
positive regulation of protein kinase activityGO:00458601440.024
skeletal system developmentGO:00015013560.024
Mouse
regulation of kinase activityGO:00435492490.023
spermatid developmentGO:00072861080.023
purine nucleotide metabolic processGO:00061633020.023
regulation of cellular component biogenesisGO:00440871810.023
Fly
telencephalon developmentGO:00215371860.023
lateral inhibitionGO:004633110.023
negative regulation of protein phosphorylationGO:00019331260.023
inorganic cation transmembrane transportGO:00986622070.023
renal system developmentGO:00720012250.023
protein localization to nucleusGO:00345041210.022
multicellular organismal response to stressGO:0033555620.022
organophosphate catabolic processGO:00464342320.022
regulation of protein kinase activityGO:00458592320.022
regulation of vacuole organizationGO:004408840.022
learning or memoryGO:00076111480.022
neuron deathGO:00709971540.022
response to organic cyclic compoundGO:00140701980.022
carbohydrate derivative biosynthetic processGO:19011371830.022
positive regulation of cellular amine metabolic processGO:003324050.022
hindbrain developmentGO:00309021280.022
response to extracellular stimulusGO:00099911270.022
Fly
regulation of proteolysisGO:00301621640.022
regulation of transferase activityGO:00513382630.021
nucleobase containing small molecule metabolic processGO:00550863520.021
regulation of bindingGO:00510981110.021
protein import into nucleusGO:0006606950.021
regulation of secretion by cellGO:19035302490.021
protein ubiquitinationGO:00165671710.021
carbohydrate metabolic processGO:00059752300.021
chromatin modificationGO:00165681870.021
negative regulation of growthGO:0045926990.021
sensory organ morphogenesisGO:00905962420.021
ras protein signal transductionGO:0007265770.020
dna metabolic processGO:00062593030.020
purine ribonucleotide metabolic processGO:00091502900.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.020
Fly
nucleoside phosphate metabolic processGO:00067533380.020
regulation of neuron projection developmentGO:00109751690.020
organic anion transportGO:00157111370.020
stem cell developmentGO:00488642190.020
purine nucleoside triphosphate catabolic processGO:00091462030.020
regulation of homeostatic processGO:00328441820.020
guanosine containing compound metabolic processGO:19010681440.020
modification dependent protein catabolic processGO:00199411330.020
negative regulation of nervous system developmentGO:00519611560.020
cation transportGO:00068123990.020
amide transportGO:00428861380.020
peptide secretionGO:00027901140.020
regulation of secretionGO:00510462740.020
negative regulation of mapk cascadeGO:0043409650.020
connective tissue developmentGO:00614481790.019
glycoprotein metabolic processGO:00091001160.019
peptidyl lysine modificationGO:0018205770.019
cellular response to hormone stimulusGO:00328701500.019
alcohol metabolic processGO:00060661160.019
positive regulation of nucleotide catabolic processGO:0030813880.019
regulation of system processGO:00440572000.019
purine ribonucleotide catabolic processGO:00091542080.019
single organism nuclear importGO:1902593950.019
immune response regulating signaling pathwayGO:00027641250.019
carbohydrate derivative catabolic processGO:19011362310.019
cellular response to lipidGO:00713961450.019
covalent chromatin modificationGO:00165691630.019
sterol metabolic processGO:0016125580.019
negative regulation of phosphorus metabolic processGO:00105631840.019
inorganic ion transmembrane transportGO:00986602340.019
cerebral cortex developmentGO:0021987860.019
rab protein signal transductionGO:003248210.019
carbohydrate homeostasisGO:00335001280.019
protein import into peroxisome matrixGO:001655830.019
organ growthGO:00352651170.019
angiogenesisGO:00015252010.019
multi multicellular organism processGO:00447061090.019
Fly
female gamete generationGO:0007292740.019
Worm Fly
regulation of erk1 and erk2 cascadeGO:0070372710.019
response to peptideGO:19016521360.018
nucleoside catabolic processGO:00091642060.018
calcium ion homeostasisGO:00550741270.018
chromatin organizationGO:00063252060.018
cytokine productionGO:00018163190.018
negative regulation of intracellular signal transductionGO:19025321670.018
response to molecule of bacterial originGO:00022371430.018
regulation of cellular component sizeGO:00325351210.018
glucose homeostasisGO:00425931280.018
striated muscle tissue developmentGO:00147062930.018
regulation of cellular response to stressGO:00801351590.018
cellular response to starvationGO:0009267570.018
Fly
response to acid chemicalGO:00011011110.018
glycerolipid biosynthetic processGO:0045017500.018
compound eye developmentGO:004874910.018
microtubule based processGO:00070172360.018
response to growth factorGO:00708481980.017
regulation of sterol transportGO:0032371170.017
positive regulation of mapk cascadeGO:00434101700.017
mitochondrion organizationGO:00070051340.017
reactive oxygen species metabolic processGO:0072593840.017
positive regulation of tor signalingGO:003200830.017
pallium developmentGO:00215431200.017
regulation of nucleocytoplasmic transportGO:0046822730.017
cell maturationGO:00484691270.017
negative regulation of blood vessel morphogenesisGO:2000181250.017
skeletal muscle organ developmentGO:00605381630.017
sterol homeostasisGO:0055092450.017
gtp metabolic processGO:00460391440.017
small gtpase mediated signal transductionGO:0007264970.017
regulation of epithelial cell proliferationGO:00506781410.017
protein oligomerizationGO:0051259670.017
positive regulation of gtpase activityGO:0043547850.016
negative regulation of cellular amine metabolic processGO:003323910.016
peptide hormone secretionGO:00300721090.016
response to sterolGO:003631440.016
cell fate commitmentGO:00451652100.016
heart morphogenesisGO:00030071780.016
regulation of purine nucleotide metabolic processGO:19005421690.016
stem cell differentiationGO:00488632680.016
glycerophospholipid metabolic processGO:0006650710.016
immune effector processGO:00022523210.016
central nervous system neuron differentiationGO:00219531620.016
regulation of peptide transportGO:0090087910.016
lipid homeostasisGO:0055088630.016
intrinsic apoptotic signaling pathwayGO:00971931320.016
leukocyte differentiationGO:00025213420.016
metal ion homeostasisGO:00550651890.016
regulation of protein serine threonine kinase activityGO:00719001570.016
oocyte axis specificationGO:000730920.016
organelle fissionGO:00482851700.016
regulation of cell projection organizationGO:00313442060.016
muscle tissue developmentGO:00605373080.016
response to nutrient levelsGO:00316671090.016
Fly
cellular response to organonitrogen compoundGO:00714171450.016
cellular protein catabolic processGO:00442571550.016
protein modification by small protein conjugationGO:00324461870.016
meiosis iGO:0007127600.015
metencephalon developmentGO:0022037890.015
anion transmembrane transportGO:0098656710.015
guanosine containing compound catabolic processGO:19010691440.015
negative regulation of cellular amino acid metabolic processGO:004576300.015
negative regulation of secretionGO:0051048610.015
lymphocyte differentiationGO:00300982420.015
regulation of lymphocyte proliferationGO:00506701170.015
negative regulation of protein processingGO:0010955790.015
regulation of cell morphogenesis involved in differentiationGO:00107691510.015
meiotic cell cycleGO:00513211220.015
regulation of membrane potentialGO:00423911920.015
regulation of purine nucleotide catabolic processGO:00331211220.015
regulation of vesicle mediated transportGO:00606271390.015
extrinsic apoptotic signaling pathwayGO:00971911260.015
dendrite developmentGO:00163581150.015
glycoprotein biosynthetic processGO:0009101890.015
phosphatidic acid biosynthetic processGO:000665420.015
positive regulation of protein serine threonine kinase activityGO:00719021060.015
reactive nitrogen species metabolic processGO:200105700.015
inorganic anion transportGO:0015698430.015
protein modification by small protein conjugation or removalGO:00706472070.015
cellular response to cytokine stimulusGO:00713451890.015
positive regulation of proteolysisGO:0045862850.014
neutral lipid metabolic processGO:0006638570.014
respiratory system developmentGO:00605411900.014
cellular alcohol biosynthetic processGO:004410830.014
organelle localizationGO:00516401790.014
Fly
epithelial tube morphogenesisGO:00605623030.014
cation homeostasisGO:00550802120.014
reactive oxygen species biosynthetic processGO:190340980.014
regulation of sequence specific dna binding transcription factor activityGO:00510901060.014
regulation of cell cycleGO:00517262810.014
negative regulation of cell proliferationGO:00082852960.014
myeloid cell homeostasisGO:00022621140.014
response to inactivityGO:001485440.014
positive regulation of cell adhesionGO:0045785800.014
negative regulation of blood vessel endothelial cell migrationGO:004353730.014
positive regulation of neuron differentiationGO:00456661410.014
positive regulation of secretionGO:00510471300.014
proteoglycan metabolic processGO:0006029380.014
positive regulation of cytokine productionGO:00018191740.014
regulation of t cell activationGO:00508631700.014
nuclear divisionGO:00002801580.014
neuron apoptotic processGO:00514021420.014
camera type eye developmentGO:00430102660.014
proteasomal protein catabolic processGO:0010498980.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.014
oocyte constructionGO:000730820.014
negative regulation of neuron projection developmentGO:0010977500.013
negative regulation of proteolysisGO:0045861740.013
blood circulationGO:00080151950.013
hormone secretionGO:00468791280.013
cellular ion homeostasisGO:00068731650.013
t cell activationGO:00421102890.013
regulation of autophagyGO:0010506300.013
response to reactive oxygen speciesGO:0000302560.013
regulation of endocytosisGO:0030100690.013
positive regulation of cysteine type endopeptidase activityGO:2001056390.013
positive regulation of purine nucleotide catabolic processGO:0033123880.013
sensory system developmentGO:004888030.013
cellular response to transforming growth factor beta stimulusGO:0071560880.013
regulation of lipid transportGO:0032368360.013
response to denervation involved in regulation of muscle adaptationGO:001489440.013
cellular metal ion homeostasisGO:00068751510.013
regulation of neuron deathGO:19012141340.013
regulation of establishment of protein localizationGO:00702011810.013
positive regulation of nucleotide metabolic processGO:00459811140.013
microtubule cytoskeleton organizationGO:00002261570.013
regulation of cell migration involved in sprouting angiogenesisGO:009004940.013
endocytosisGO:00068971680.013
Fly
epithelial cell proliferationGO:00506731740.013
cation transmembrane transportGO:00986552660.013
regulation of ossificationGO:00302781120.013
gastrulationGO:00073691160.013
synapsisGO:0007129340.013
cellular response to dna damage stimulusGO:00069742070.012
response to inorganic substanceGO:0010035960.012
cellular chemical homeostasisGO:00550822150.012
hematopoietic progenitor cell differentiationGO:00022441430.012
glycerophospholipid biosynthetic processGO:0046474320.012
cellular response to oxidative stressGO:0034599760.012
osteoclast differentiationGO:0030316620.012
regulation of blood pressureGO:0008217930.012
response to oxidative stressGO:00069791230.012
cardiac chamber morphogenesisGO:0003206930.012
establishment of protein localization to membraneGO:0090150540.012
positive regulation of apoptotic signaling pathwayGO:2001235950.012
inflammatory responseGO:00069542440.012
small molecule biosynthetic processGO:00442831320.012
learningGO:0007612980.012
negative regulation of protein modification processGO:00314001630.012
cardiac muscle tissue developmentGO:00487381300.012
negative regulation of cell developmentGO:00107211690.012
positive regulation of intracellular transportGO:0032388700.012
heterocycle catabolic processGO:00467002800.012
multicellular organismal homeostasisGO:00488711640.012
regulation of neuron apoptotic processGO:00435231220.012
divalent inorganic cation transportGO:00725111780.012
sensory perception of touchGO:005097520.012
negative regulation of kinase activityGO:0033673810.012
positive regulation of growthGO:00459271040.012
response to ammonium ionGO:0060359210.012
negative regulation of angiogenesisGO:0016525250.011
regulation of lymphocyte activationGO:00512492400.011
cellular response to lipopolysaccharideGO:0071222770.011
developmental maturationGO:00217001930.011
regulation of cell sizeGO:0008361720.011
response to monosaccharideGO:0034284670.011
regulation of cysteine type endopeptidase activityGO:2000116650.011
regulation of nucleotide metabolic processGO:00061401690.011
negative regulation of ossificationGO:0030279490.011
regulation of vasculature developmentGO:1901342880.011
vesicle localizationGO:0051648860.011
Fly
memoryGO:0007613580.011
meiotic nuclear divisionGO:00071261150.011
organic hydroxy compound transportGO:0015850930.011
positive regulation of organelle organizationGO:00106381280.011
reproductive behaviorGO:0019098320.011
Fly
positive regulation of protein transportGO:0051222930.011
protein kinase b signalingGO:0043491740.011
steroid biosynthetic processGO:0006694470.011
response to temperature stimulusGO:0009266550.011
t cell proliferationGO:00420981200.011
response to oxygen levelsGO:0070482620.011
protein heterooligomerizationGO:0051291140.011
hair cell differentiationGO:0035315400.011
regulation of apoptotic signaling pathwayGO:20012331970.011
cellular response to peptideGO:1901653920.011
carboxylic acid transportGO:00469421000.011
positive regulation of steroid biosynthetic processGO:001089340.011
proteoglycan biosynthetic processGO:0030166200.011
sodium ion transportGO:0006814730.011
transforming growth factor beta receptor signaling pathwayGO:0007179710.011
transmission of nerve impulseGO:0019226760.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.011
insulin receptor signaling pathwayGO:0008286490.011
cellular macromolecule catabolic processGO:00442652060.011
multicellular organismal agingGO:0010259240.010
ribose phosphate metabolic processGO:00196932910.010
chemotaxisGO:00069352470.010
retina morphogenesis in camera type eyeGO:0060042450.010
negative regulation of protein maturationGO:1903318790.010
neural tube developmentGO:00219151600.010
circulatory system processGO:00030131970.010
response to alkaloidGO:0043279340.010
regulation of lipid biosynthetic processGO:0046890540.010
peptidyl proline hydroxylationGO:001951130.010
regulation of cell growthGO:0001558910.010
regulation of response to woundingGO:19030341890.010
gtp catabolic processGO:00061841430.010
negative regulation of neuron deathGO:1901215980.010
erk1 and erk2 cascadeGO:0070371770.010
organic hydroxy compound biosynthetic processGO:1901617770.010
macromolecule methylationGO:00434141200.010
lipid transportGO:0006869980.010
Mouse
dephosphorylationGO:00163111290.010
meiotic cell cycle processGO:1903046770.010
cell divisionGO:00513011200.010
eye photoreceptor cell differentiationGO:0001754410.010
protein localization to peroxisomeGO:007266240.010
regulation of hormone secretionGO:0046883880.010
regulation of bmp signaling pathwayGO:0030510600.010
negative regulation of organelle organizationGO:0010639900.010
regulation of body fluid levelsGO:00508781620.010
lipoprotein metabolic processGO:0042157430.010
ear developmentGO:00435832000.010
positive regulation of macroautophagyGO:001623930.010
cell adhesionGO:00071553290.010

Spns1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:33100.033
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.033
neurodegenerative diseaseDOID:128900.021
heart diseaseDOID:11400.016
cardiovascular system diseaseDOID:128700.016
disease of cellular proliferationDOID:1456600.012
immune system diseaseDOID:291400.010