| regulation of cellular catabolic process | GO:0031329 | 242 | 0.497 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.276 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.219 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.211 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.208 | |
| fibroblast growth factor receptor signaling pathway | GO:0008543 | 46 | 0.173 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.159 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.146 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.140 | |
| intra s dna damage checkpoint | GO:0031573 | 4 | 0.130 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.125 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.122 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.111 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.106 | |
| cellular homeostasis | GO:0019725 | 240 | 0.094 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.091 | |
| axonogenesis | GO:0007409 | 274 | 0.087 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.085 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.083 | |
| positive regulation of sequestering of triglyceride | GO:0010890 | 4 | 0.079 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.075 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.074 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.074 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.073 | |
| synaptic transmission | GO:0007268 | 329 | 0.072 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.070 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.070 | Human Fly |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.067 | |
| transition metal ion homeostasis | GO:0055076 | 54 | 0.067 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.064 | |
| phospholipid metabolic process | GO:0006644 | 87 | 0.061 | |
| cellular transition metal ion homeostasis | GO:0046916 | 32 | 0.060 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.060 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.059 | |
| maintenance of location | GO:0051235 | 89 | 0.059 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.057 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.057 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.055 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.054 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.051 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.050 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.046 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.044 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.044 | |
| neuron projection guidance | GO:0097485 | 141 | 0.043 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.042 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.042 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.041 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.041 | |
| lipid localization | GO:0010876 | 126 | 0.041 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.041 | |
| early endosome to late endosome transport | GO:0045022 | 2 | 0.039 | |
| regulation of protein kinase b signaling | GO:0051896 | 56 | 0.039 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.039 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.038 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.038 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.038 | Human |
| mitotic cell cycle | GO:0000278 | 195 | 0.037 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.037 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.036 | |
| protein ubiquitination | GO:0016567 | 171 | 0.036 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.036 | |
| positive regulation of rho gtpase activity | GO:0032321 | 41 | 0.036 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.034 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.033 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.033 | |
| organelle localization | GO:0051640 | 179 | 0.033 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.032 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.032 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.032 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.031 | |
| regulation of ras gtpase activity | GO:0032318 | 88 | 0.031 | |
| cation homeostasis | GO:0055080 | 212 | 0.031 | |
| phosphatidylinositol metabolic process | GO:0046488 | 45 | 0.031 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.030 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.030 | |
| glycerophospholipid metabolic process | GO:0006650 | 71 | 0.030 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.030 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.029 | |
| microtubule based process | GO:0007017 | 236 | 0.029 | Human |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.028 | |
| regulation of cell size | GO:0008361 | 72 | 0.028 | |
| exocytosis | GO:0006887 | 121 | 0.028 | |
| cell adhesion | GO:0007155 | 329 | 0.027 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 45 | 0.027 | |
| regulation of rho gtpase activity | GO:0032319 | 58 | 0.027 | |
| neuron apoptotic process | GO:0051402 | 142 | 0.027 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.026 | |
| regulation of transforming growth factor beta receptor signaling pathway | GO:0017015 | 43 | 0.025 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.025 | |
| positive regulation of gtp catabolic process | GO:0033126 | 85 | 0.025 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.024 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 85 | 0.024 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.024 | |
| membrane organization | GO:0061024 | 245 | 0.024 | |
| chromatin modification | GO:0016568 | 187 | 0.023 | |
| lipid modification | GO:0030258 | 65 | 0.023 | |
| chromatin organization | GO:0006325 | 206 | 0.023 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.023 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.022 | |
| histone modification | GO:0016570 | 159 | 0.022 | |
| regulation of secretion | GO:0051046 | 274 | 0.022 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.022 | |
| forebrain development | GO:0030900 | 302 | 0.022 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.021 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.021 | |
| positive regulation of growth | GO:0045927 | 104 | 0.021 | |
| transmembrane transport | GO:0055085 | 412 | 0.021 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 112 | 0.021 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.021 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.021 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.021 | |
| multicellular organismal macromolecule catabolic process | GO:0044266 | 1 | 0.021 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.020 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 127 | 0.020 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.020 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.020 | |
| cation transport | GO:0006812 | 399 | 0.019 | |
| response to endoplasmic reticulum stress | GO:0034976 | 53 | 0.019 | |
| response to nutrient levels | GO:0031667 | 109 | 0.019 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.019 | |
| cell growth | GO:0016049 | 130 | 0.019 | |
| response to growth factor | GO:0070848 | 198 | 0.018 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.018 | |
| regulation of epithelial cell migration | GO:0010632 | 35 | 0.018 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.018 | |
| cytoskeleton dependent intracellular transport | GO:0030705 | 50 | 0.018 | |
| regulation of protein transport | GO:0051223 | 163 | 0.018 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 88 | 0.018 | |
| endodermal cell fate specification | GO:0001714 | 4 | 0.018 | |
| protein localization to organelle | GO:0033365 | 185 | 0.018 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.018 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 80 | 0.018 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.017 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.017 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.017 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.017 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.017 | |
| gene silencing | GO:0016458 | 38 | 0.017 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.017 | |
| cellular iron ion homeostasis | GO:0006879 | 16 | 0.016 | |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.016 | |
| regulation of ion transport | GO:0043269 | 215 | 0.016 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.016 | |
| dna integrity checkpoint | GO:0031570 | 28 | 0.016 | |
| cellularization | GO:0007349 | 1 | 0.016 | |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.016 | |
| lipid transport | GO:0006869 | 98 | 0.016 | |
| regulation of cell motility | GO:2000145 | 236 | 0.016 | |
| response to fibroblast growth factor | GO:0071774 | 47 | 0.015 | |
| phospholipid biosynthetic process | GO:0008654 | 36 | 0.015 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.015 | |
| positive regulation of fibroblast growth factor receptor signaling pathway | GO:0045743 | 3 | 0.015 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.015 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.015 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.014 | |
| protein catabolic process | GO:0030163 | 221 | 0.014 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.014 | |
| positive regulation of mitotic sister chromatid separation | GO:1901970 | 2 | 0.014 | |
| mitotic spindle organization | GO:0007052 | 10 | 0.014 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.014 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.014 | |
| positive regulation of gtpase activity | GO:0043547 | 85 | 0.014 | |
| mapk cascade | GO:0000165 | 281 | 0.014 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.014 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 88 | 0.013 | |
| mitotic sister chromatid cohesion | GO:0007064 | 1 | 0.013 | |
| muscle cell proliferation | GO:0033002 | 52 | 0.013 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.013 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.013 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.013 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.013 | |
| positive regulation of transforming growth factor beta2 production | GO:0032915 | 2 | 0.013 | |
| endomembrane system organization | GO:0010256 | 147 | 0.013 | |
| positive regulation of rac protein signal transduction | GO:0035022 | 1 | 0.013 | |
| organelle assembly | GO:0070925 | 177 | 0.013 | |
| nuclear division | GO:0000280 | 158 | 0.012 | |
| negative regulation of synapse assembly | GO:0051964 | 3 | 0.012 | |
| glycoprotein metabolic process | GO:0009100 | 116 | 0.012 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.012 | |
| positive regulation of cell cycle process | GO:0090068 | 61 | 0.012 | |
| negative regulation of cellular catabolic process | GO:0031330 | 47 | 0.012 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.012 | |
| negative regulation of cellular response to growth factor stimulus | GO:0090288 | 46 | 0.012 | |
| macromolecule methylation | GO:0043414 | 120 | 0.012 | |
| negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090101 | 61 | 0.012 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.012 | |
| regulation of cell migration | GO:0030334 | 219 | 0.012 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.012 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.012 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.012 | |
| negative regulation of cell cycle process | GO:0010948 | 69 | 0.011 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.011 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.011 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 48 | 0.011 | |
| actin filament organization | GO:0007015 | 113 | 0.011 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.011 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.011 | |
| receptor biosynthetic process | GO:0032800 | 3 | 0.011 | |
| regulation of rho protein signal transduction | GO:0035023 | 71 | 0.011 | |
| myeloid leukocyte activation | GO:0002274 | 83 | 0.011 | |
| regulation of innate immune response | GO:0045088 | 91 | 0.011 | |
| positive regulation of secretion | GO:0051047 | 130 | 0.011 | |
| regulation of transforming growth factor beta2 production | GO:0032909 | 2 | 0.011 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.011 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.011 | |
| positive regulation of neuron differentiation | GO:0045666 | 141 | 0.011 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.011 | |
| rna polymerase ii transcriptional preinitiation complex assembly | GO:0051123 | 3 | 0.011 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.010 | |
| body morphogenesis | GO:0010171 | 45 | 0.010 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.010 | |
| negative regulation of cell size | GO:0045792 | 3 | 0.010 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.010 | |
| negative regulation of serotonin secretion | GO:0014063 | 2 | 0.010 | |