IMP: Integrative Multi-species Prediction

Mus musculus

40 known processes

Ccdc66

coiled-coil domain containing 66

(Aliases: E230015L20Rik)

Entrez: 320234
Ensembl: ENSMUSG00000046753
UniProtKB: Q6NS45

Process Predictions
Disease Predictions

Ccdc66 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cilium morphogenesis	GO:0060271	102	0.069
dna metabolic process	GO:0006259	303	0.052
cilium assembly	GO:0042384	81	0.052
microtubule based process	GO:0007017	236	0.043
regulation of cellular amino acid metabolic process	GO:0006521	5	0.031
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.027
microtubule cytoskeleton organization	GO:0000226	157	0.027
cellular amine metabolic process	GO:0044106	44	0.027
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.027
cellular amino acid metabolic process	GO:0006520	103	0.026
macromolecule methylation	GO:0043414	120	0.026
regulation of organelle organization	GO:0033043	289	0.026
cellular nitrogen compound catabolic process	GO:0044270	280	0.026
organelle assembly	GO:0070925	177	0.025
muscle tissue development	GO:0060537	308	0.024
sensory organ morphogenesis	GO:0090596	242	0.024
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.023
forebrain development	GO:0030900	302	0.023
negative regulation of cell proliferation	GO:0008285	296	0.023
immune effector process	GO:0002252	321	0.022
regionalization	GO:0003002	337	0.022
stem cell differentiation	GO:0048863	268	0.022
regulation of cellular amine metabolic process	GO:0033238	20	0.022
organophosphate catabolic process	GO:0046434	232	0.021
cellular ketone metabolic process	GO:0042180	84	0.021
regulation of protein localization	GO:0032880	231	0.021
amine metabolic process	GO:0009308	45	0.021
cellular component assembly involved in morphogenesis	GO:0010927	139	0.021
muscle cell differentiation	GO:0042692	261	0.021
cytoskeleton dependent intracellular transport	GO:0030705	50	0.021
methylation	GO:0032259	134	0.021
cellular response to dna damage stimulus	GO:0006974	207	0.021
small gtpase mediated signal transduction	GO:0007264	97	0.020
hematopoietic progenitor cell differentiation	GO:0002244	143	0.019
apoptotic signaling pathway	GO:0097190	306	0.019
camera type eye development	GO:0043010	266	0.019
cation transport	GO:0006812	399	0.019
ribonucleoside catabolic process	GO:0042454	206	0.019
regulation of cellular ketone metabolic process	GO:0010565	66	0.019
regulation of cell cycle	GO:0051726	281	0.019
nucleobase containing small molecule metabolic process	GO:0055086	352	0.019
positive regulation of cellular amine metabolic process	GO:0033240	5	0.019
purine ribonucleoside metabolic process	GO:0046128	241	0.018
nucleotide metabolic process	GO:0009117	332	0.018
nucleoside phosphate metabolic process	GO:0006753	338	0.018
purine nucleotide catabolic process	GO:0006195	211	0.018
transmembrane transport	GO:0055085	412	0.017
protein ubiquitination	GO:0016567	171	0.017
fat cell differentiation	GO:0045444	160	0.017
lymphocyte differentiation	GO:0030098	242	0.017
purine nucleotide metabolic process	GO:0006163	302	0.016
purine containing compound metabolic process	GO:0072521	311	0.016
negative regulation of protein metabolic process	GO:0051248	282	0.016
skeletal system development	GO:0001501	356	0.016
telencephalon development	GO:0021537	186	0.016
nucleoside phosphate catabolic process	GO:1901292	222	0.016
ribonucleotide metabolic process	GO:0009259	291	0.016
cellular homeostasis	GO:0019725	240	0.016
smoothened signaling pathway	GO:0007224	105	0.016
multicellular organism growth	GO:0035264	161	0.016
protein modification by small protein conjugation	GO:0032446	187	0.016
dna alkylation	GO:0006305	43	0.016
purine ribonucleotide catabolic process	GO:0009154	208	0.016
striated muscle tissue development	GO:0014706	293	0.016
protein localization to organelle	GO:0033365	185	0.016
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.016
stem cell maintenance	GO:0019827	130	0.015
macromolecule catabolic process	GO:0009057	281	0.015
purine containing compound catabolic process	GO:0072523	213	0.015
ossification	GO:0001503	216	0.015
purine ribonucleoside catabolic process	GO:0046130	205	0.015
aromatic compound catabolic process	GO:0019439	286	0.015
stem cell development	GO:0048864	219	0.015
organic cyclic compound catabolic process	GO:1901361	295	0.015
heterocycle catabolic process	GO:0046700	280	0.015
cation transmembrane transport	GO:0098655	266	0.015
membrane organization	GO:0061024	245	0.015
posttranscriptional regulation of gene expression	GO:0010608	155	0.015
glycosyl compound metabolic process	GO:1901657	246	0.015
regulation of cell activation	GO:0050865	289	0.015
t cell activation	GO:0042110	289	0.015
regulation of transferase activity	GO:0051338	263	0.014
leukocyte differentiation	GO:0002521	342	0.014
response to organonitrogen compound	GO:0010243	246	0.014
ribonucleoside metabolic process	GO:0009119	245	0.014
negative regulation of immune system process	GO:0002683	209	0.014
positive regulation of protein modification process	GO:0031401	299	0.014
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.014
cytokine production	GO:0001816	319	0.014
intraciliary retrograde transport	GO:0035721	3	0.014
nucleoside triphosphate catabolic process	GO:0009143	205	0.014
organelle localization	GO:0051640	179	0.014
purine nucleoside metabolic process	GO:0042278	241	0.014
anatomical structure homeostasis	GO:0060249	145	0.014
homeostasis of number of cells	GO:0048872	210	0.014
negative regulation of cellular component organization	GO:0051129	194	0.013
negative regulation of cellular protein metabolic process	GO:0032269	247	0.013
glycosyl compound catabolic process	GO:1901658	206	0.013
negative regulation of lymphocyte activation	GO:0051250	91	0.013
skeletal muscle organ development	GO:0060538	163	0.013
dna repair	GO:0006281	107	0.013
neural tube development	GO:0021915	160	0.013
protein polymerization	GO:0051258	57	0.013
organonitrogen compound catabolic process	GO:1901565	264	0.013
cell division	GO:0051301	120	0.013
microtubule based movement	GO:0007018	84	0.013
ribonucleotide catabolic process	GO:0009261	208	0.013
ras protein signal transduction	GO:0007265	77	0.013
protein modification by small protein conjugation or removal	GO:0070647	207	0.013
regulation of establishment of protein localization	GO:0070201	181	0.013
dna modification	GO:0006304	50	0.013
negative regulation of molecular function	GO:0044092	258	0.013
organelle fission	GO:0048285	170	0.013
peptidyl amino acid modification	GO:0018193	336	0.013
regulation of secretion	GO:0051046	274	0.013
rna processing	GO:0006396	105	0.013
microtubule based transport	GO:0010970	50	0.013
carbohydrate derivative catabolic process	GO:1901136	231	0.013
carbohydrate metabolic process	GO:0005975	230	0.012
nitrogen compound transport	GO:0071705	271	0.012
nuclear division	GO:0000280	158	0.012
glucose homeostasis	GO:0042593	128	0.012
chromatin organization	GO:0006325	206	0.012
regulation of cell cycle process	GO:0010564	160	0.012
negative regulation of cell development	GO:0010721	169	0.012
retina development in camera type eye	GO:0060041	119	0.012
response to growth factor	GO:0070848	198	0.012
sensory perception	GO:0007600	245	0.012
positive regulation of cell development	GO:0010720	237	0.012
protein catabolic process	GO:0030163	221	0.012
protein localization to membrane	GO:0072657	108	0.012
muscle cell development	GO:0055001	133	0.012
positive regulation of programmed cell death	GO:0043068	218	0.012
purine nucleoside catabolic process	GO:0006152	205	0.012
regulation of cytoskeleton organization	GO:0051493	122	0.012
cellular response to hormone stimulus	GO:0032870	150	0.012
purine ribonucleotide metabolic process	GO:0009150	290	0.012
protein maturation	GO:0051604	176	0.012
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.012
g protein coupled receptor signaling pathway	GO:0007186	243	0.012
regulation of lymphocyte activation	GO:0051249	240	0.012
inorganic cation transmembrane transport	GO:0098662	207	0.012
regulation of homeostatic process	GO:0032844	182	0.012
nucleoside catabolic process	GO:0009164	206	0.012
cell type specific apoptotic process	GO:0097285	268	0.011
ribose phosphate metabolic process	GO:0019693	291	0.011
ion transmembrane transport	GO:0034220	361	0.011
dna recombination	GO:0006310	92	0.011
ear development	GO:0043583	200	0.011
negative regulation of organelle organization	GO:0010639	90	0.011
cellular response to cytokine stimulus	GO:0071345	189	0.011
regulation of proteolysis	GO:0030162	164	0.011
respiratory system development	GO:0060541	190	0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.011
mitotic cell cycle process	GO:1903047	159	0.011
circulatory system process	GO:0003013	197	0.011
epithelial cell proliferation	GO:0050673	174	0.011
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.011
regulation of cell adhesion	GO:0030155	154	0.011
myeloid cell differentiation	GO:0030099	233	0.011
positive regulation of cellular catabolic process	GO:0031331	148	0.011
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.011
regulation of cellular catabolic process	GO:0031329	242	0.011
renal system development	GO:0072001	225	0.011
positive regulation of hydrolase activity	GO:0051345	148	0.011
nucleoside metabolic process	GO:0009116	246	0.011
nucleotide catabolic process	GO:0009166	217	0.011
negative regulation of protein modification process	GO:0031400	163	0.011
inorganic ion transmembrane transport	GO:0098660	234	0.011
urogenital system development	GO:0001655	261	0.011
muscle fiber development	GO:0048747	76	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.011
spermatid development	GO:0007286	108	0.011
adult behavior	GO:0030534	135	0.011
regulation of secretion by cell	GO:1903530	249	0.011
regulation of cell motility	GO:2000145	236	0.011
response to transforming growth factor beta	GO:0071559	88	0.011
skin development	GO:0043588	220	0.011
b cell activation	GO:0042113	161	0.011
multicellular organismal homeostasis	GO:0048871	164	0.011
regulation of membrane potential	GO:0042391	192	0.010
positive regulation of organelle organization	GO:0010638	128	0.010
heart morphogenesis	GO:0003007	178	0.010
appendage development	GO:0048736	166	0.010
regulation of hormone levels	GO:0010817	211	0.010
mitotic cell cycle	GO:0000278	195	0.010
cellular lipid metabolic process	GO:0044255	323	0.010
maintenance of location	GO:0051235	89	0.010
cytoplasmic transport	GO:0016482	234	0.010
regulation of lymphocyte differentiation	GO:0045619	107	0.010
regulation of chromosome organization	GO:0033044	83	0.010
establishment of organelle localization	GO:0051656	122	0.010
striated muscle cell development	GO:0055002	125	0.010

Ccdc66 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.025
disease of anatomical entity	DOID:7	0.025
cancer	DOID:162	0.019
organ system cancer	DOID:0050686	0.019
disease of cellular proliferation	DOID:14566	0.019
eye and adnexa disease	DOID:1492	0.013
sensory system disease	DOID:0050155	0.013
immune system disease	DOID:2914	0.013
eye disease	DOID:5614	0.012
retinal disease	DOID:5679	0.011

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