| mrna metabolic process | GO:0016071 | 84 | 0.487 | |
| rna splicing via transesterification reactions | GO:0000375 | 43 | 0.337 | |
| rna splicing via transesterification reactions with bulged adenosine as nucleophile | GO:0000377 | 43 | 0.308 | |
| mrna splicing via spliceosome | GO:0000398 | 43 | 0.265 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.229 | |
| rna splicing | GO:0008380 | 54 | 0.193 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.174 | |
| mrna processing | GO:0006397 | 63 | 0.153 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.148 | |
| rna processing | GO:0006396 | 105 | 0.145 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.141 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.139 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.128 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.113 | |
| amine metabolic process | GO:0009308 | 45 | 0.104 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.101 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.099 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.099 | |
| endocytosis | GO:0006897 | 168 | 0.093 | |
| ear development | GO:0043583 | 200 | 0.093 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.089 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.086 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.085 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.084 | |
| regulation of mrna metabolic process | GO:1903311 | 43 | 0.082 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.078 | |
| regulation of mrna splicing via spliceosome | GO:0048024 | 32 | 0.077 | |
| response to topologically incorrect protein | GO:0035966 | 25 | 0.075 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.065 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.064 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.064 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.063 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.060 | |
| regulation of mrna processing | GO:0050684 | 41 | 0.058 | |
| germ cell development | GO:0007281 | 185 | 0.058 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.057 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.056 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.055 | |
| organelle assembly | GO:0070925 | 177 | 0.054 | |
| stem cell differentiation | GO:0048863 | 268 | 0.053 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.052 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.048 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.048 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.047 | |
| multicellular organism growth | GO:0035264 | 161 | 0.047 | |
| regulation of binding | GO:0051098 | 111 | 0.046 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 94 | 0.045 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.045 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.045 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.045 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.044 | |
| regulation of rna splicing | GO:0043484 | 37 | 0.044 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.044 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.044 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.043 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.042 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.041 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.041 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.040 | |
| nuclear division | GO:0000280 | 158 | 0.039 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.038 | |
| mapk cascade | GO:0000165 | 281 | 0.038 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.037 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.037 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.037 | |
| chromatin modification | GO:0016568 | 187 | 0.036 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.035 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.034 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.034 | |
| camera type eye development | GO:0043010 | 266 | 0.033 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.033 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.033 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.033 | |
| meiotic cell cycle process | GO:1903046 | 77 | 0.033 | |
| ribonucleoprotein complex subunit organization | GO:0071826 | 28 | 0.032 | |
| alternative mrna splicing via spliceosome | GO:0000380 | 12 | 0.032 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.031 | |
| actin filament organization | GO:0007015 | 113 | 0.031 | |
| cellular response to topologically incorrect protein | GO:0035967 | 25 | 0.031 | |
| response to endoplasmic reticulum stress | GO:0034976 | 53 | 0.030 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.030 | |
| cation transport | GO:0006812 | 399 | 0.029 | |
| poly a mrna export from nucleus | GO:0016973 | 4 | 0.029 | |
| retina development in camera type eye | GO:0060041 | 119 | 0.028 | |
| dna templated transcription termination | GO:0006353 | 4 | 0.028 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.028 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.028 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.028 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.028 | |
| nuclear transcribed mrna catabolic process | GO:0000956 | 16 | 0.028 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.028 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.027 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.027 | |
| response to acid chemical | GO:0001101 | 111 | 0.027 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.027 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.026 | |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.026 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.026 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.026 | |
| cytokine production | GO:0001816 | 319 | 0.026 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.026 | |
| activation of immune response | GO:0002253 | 138 | 0.026 | |
| epidermis development | GO:0008544 | 187 | 0.025 | |
| positive regulation of gtpase activity | GO:0043547 | 85 | 0.025 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.024 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.024 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.024 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.024 | |
| viral life cycle | GO:0019058 | 36 | 0.024 | |
| establishment of rna localization | GO:0051236 | 18 | 0.023 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.023 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.023 | |
| dendrite development | GO:0016358 | 115 | 0.023 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.023 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.023 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.023 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.023 | |
| negative regulation of mrna processing | GO:0050686 | 12 | 0.023 | |
| neuron death | GO:0070997 | 154 | 0.022 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.022 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.022 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.022 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.022 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.022 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.022 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.021 | |
| microtubule based process | GO:0007017 | 236 | 0.021 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 83 | 0.021 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.021 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.021 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.021 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.021 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.021 | |
| t cell differentiation | GO:0030217 | 174 | 0.020 | |
| spermatogenesis | GO:0007283 | 284 | 0.020 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.020 | |
| nucleic acid transport | GO:0050657 | 18 | 0.020 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.020 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.020 | |
| stem cell development | GO:0048864 | 219 | 0.020 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.019 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.019 | |
| protein localization to organelle | GO:0033365 | 185 | 0.019 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.019 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.019 | |
| membrane organization | GO:0061024 | 245 | 0.018 | |
| negative regulation of mrna splicing via spliceosome | GO:0048025 | 12 | 0.018 | |
| negative regulation of rna splicing | GO:0033119 | 12 | 0.018 | |
| positive regulation of apoptotic process involved in mammary gland involution | GO:0060058 | 4 | 0.018 | |
| t cell activation | GO:0042110 | 289 | 0.018 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.018 | |
| cellular homeostasis | GO:0019725 | 240 | 0.018 | |
| skin development | GO:0043588 | 220 | 0.017 | |
| negative regulation of cell cycle process | GO:0010948 | 69 | 0.017 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.017 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.017 | |
| gtp catabolic process | GO:0006184 | 143 | 0.017 | |
| male gamete generation | GO:0048232 | 285 | 0.017 | |
| response to unfolded protein | GO:0006986 | 21 | 0.017 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.017 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.017 | |
| regulation of gtp catabolic process | GO:0033124 | 113 | 0.017 | |
| viral process | GO:0016032 | 41 | 0.017 | |
| central nervous system morphogenesis | GO:0021551 | 2 | 0.017 | |
| organelle fission | GO:0048285 | 170 | 0.016 | |
| leukocyte migration | GO:0050900 | 124 | 0.016 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.016 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.016 | |
| sequestering of calcium ion | GO:0051208 | 18 | 0.016 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.016 | |
| nuclear transport | GO:0051169 | 139 | 0.016 | |
| gland development | GO:0048732 | 330 | 0.016 | |
| mitotic cytokinesis | GO:0000281 | 4 | 0.016 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.016 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.016 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.016 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.016 | |
| nuclear transcribed mrna catabolic process nonsense mediated decay | GO:0000184 | 1 | 0.016 | |
| er nucleus signaling pathway | GO:0006984 | 27 | 0.016 | |
| protein oligomerization | GO:0051259 | 67 | 0.016 | |
| peptidyl serine modification | GO:0018209 | 83 | 0.015 | |
| response to amino acid | GO:0043200 | 37 | 0.015 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.015 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 59 | 0.015 | |
| regulation of cell adhesion | GO:0030155 | 154 | 0.015 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.015 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.015 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.015 | |
| regulation of meiotic cell cycle | GO:0051445 | 34 | 0.015 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.015 | |
| transcription coupled nucleotide excision repair | GO:0006283 | 2 | 0.015 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.015 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.015 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.014 | |
| regulation of cell motility | GO:2000145 | 236 | 0.014 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.014 | |
| mitochondrion organization | GO:0007005 | 134 | 0.014 | |
| membrane fusion | GO:0061025 | 38 | 0.014 | |
| regulation of cell activation | GO:0050865 | 289 | 0.014 | |
| regulation of ion transport | GO:0043269 | 215 | 0.014 | |
| cell adhesion | GO:0007155 | 329 | 0.014 | |
| atp catabolic process | GO:0006200 | 55 | 0.014 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.014 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.014 | |
| regulation of protein heterodimerization activity | GO:0043497 | 2 | 0.014 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.014 | |
| cell cycle checkpoint | GO:0000075 | 47 | 0.014 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.014 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.014 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.013 | |
| transmembrane transport | GO:0055085 | 412 | 0.013 | |
| sensory perception | GO:0007600 | 245 | 0.013 | |
| protein catabolic process | GO:0030163 | 221 | 0.013 | |
| gtp metabolic process | GO:0046039 | 144 | 0.013 | |
| ubiquitin dependent smad protein catabolic process | GO:0030579 | 2 | 0.013 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.013 | |
| regulation of cell migration | GO:0030334 | 219 | 0.013 | |
| mitochondrial outer membrane permeabilization involved in programmed cell death | GO:1902686 | 11 | 0.013 | |
| ameboidal type cell migration | GO:0001667 | 128 | 0.013 | |
| actin polymerization or depolymerization | GO:0008154 | 54 | 0.013 | |
| positive regulation of transcription elongation from rna polymerase ii promoter | GO:0032968 | 2 | 0.013 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.013 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.013 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 88 | 0.013 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.013 | |
| positive regulation of protein complex assembly | GO:0031334 | 45 | 0.013 | |
| immune response regulating cell surface receptor signaling pathway | GO:0002768 | 80 | 0.013 | |
| interspecies interaction between organisms | GO:0044419 | 83 | 0.012 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.012 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.012 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.012 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.012 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.012 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.012 | |
| axonal fasciculation | GO:0007413 | 15 | 0.012 | |
| negative regulation of mrna metabolic process | GO:1903312 | 13 | 0.012 | |
| vesicle organization | GO:0016050 | 60 | 0.012 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.012 | |
| rna interference | GO:0016246 | 2 | 0.012 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.012 | |
| t cell differentiation in thymus | GO:0033077 | 77 | 0.012 | |
| regulation of response to alcohol | GO:1901419 | 2 | 0.012 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.012 | |
| response to oxidative stress | GO:0006979 | 123 | 0.012 | |
| endoplasmic reticulum unfolded protein response | GO:0030968 | 19 | 0.012 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.012 | |
| rna polymerase ii transcriptional preinitiation complex assembly | GO:0051123 | 3 | 0.012 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.012 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.012 | |
| neuroepithelial cell differentiation | GO:0060563 | 37 | 0.012 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.012 | |
| atp metabolic process | GO:0046034 | 75 | 0.012 | |
| dna templated transcription elongation | GO:0006354 | 13 | 0.012 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 71 | 0.012 | |
| nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 49 | 0.012 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.012 | |
| negative regulation of neuron death | GO:1901215 | 98 | 0.011 | |
| regulation of dna templated transcription termination | GO:0031554 | 1 | 0.011 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.011 | |
| positive regulation of developmental pigmentation | GO:0048087 | 6 | 0.011 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 57 | 0.011 | |
| mesenchymal cell differentiation | GO:0048762 | 107 | 0.011 | |
| cell division | GO:0051301 | 120 | 0.011 | |
| chemotaxis | GO:0006935 | 247 | 0.011 | |
| regulation of protein stability | GO:0031647 | 52 | 0.011 | |
| response to light stimulus | GO:0009416 | 135 | 0.011 | |
| gene silencing by rna | GO:0031047 | 19 | 0.011 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.011 | |
| female gamete generation | GO:0007292 | 74 | 0.011 | |
| peptidyl tyrosine modification | GO:0018212 | 145 | 0.011 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 143 | 0.011 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.011 | |
| spermatid differentiation | GO:0048515 | 115 | 0.011 | |
| ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway | GO:0043162 | 3 | 0.011 | |
| protein localization to membrane | GO:0072657 | 108 | 0.011 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.011 | |
| immune response activating signal transduction | GO:0002757 | 116 | 0.011 | |
| regulation of protein complex disassembly | GO:0043244 | 28 | 0.011 | |
| fat cell differentiation | GO:0045444 | 160 | 0.011 | |
| mammary gland epithelium development | GO:0061180 | 65 | 0.011 | |
| cellular response to misfolded protein | GO:0071218 | 5 | 0.011 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.011 | |
| receptor mediated endocytosis | GO:0006898 | 51 | 0.011 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 48 | 0.011 | |
| protein polymerization | GO:0051258 | 57 | 0.011 | |
| apoptotic process involved in mammary gland involution | GO:0060057 | 4 | 0.011 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.011 | |
| negative regulation of translation | GO:0017148 | 22 | 0.010 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.010 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.010 | |
| response to growth factor | GO:0070848 | 198 | 0.010 | |
| negative regulation of neuron apoptotic process | GO:0043524 | 92 | 0.010 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.010 | |
| mitochondrial fragmentation involved in apoptotic process | GO:0043653 | 1 | 0.010 | |
| dephosphorylation | GO:0016311 | 129 | 0.010 | |
| mrna catabolic process | GO:0006402 | 22 | 0.010 | |
| regulation of skeletal muscle fiber development | GO:0048742 | 36 | 0.010 | |
| rhythmic process | GO:0048511 | 174 | 0.010 | |
| regulation of neuron death | GO:1901214 | 134 | 0.010 | |
| inner ear receptor cell differentiation | GO:0060113 | 61 | 0.010 | |
| erk1 and erk2 cascade | GO:0070371 | 77 | 0.010 | |
| mitotic nuclear division | GO:0007067 | 48 | 0.010 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.010 | |
